oO , ; 3/ Rockefeller THE ROCKEFELLER UNIVERSITY a University Ke 1230 YORK AVENUE - NEW YORK. NEW YORK 10021 Oy 1gol Lv C 55r O OFFICE OF THE PRESIDENT 21 February 1979 Professor Vincent Dole | The Rockefeller University Dear Vince: t Thanks for your note about Extein's paper regarding the distinctions he believes should be made between "state" and "trait" disorders. Quite . frankly, I have never been a fan of psychiatry of this sort. So, as a well-informed amateur, I had come to the same conclusion you did and I was delighted to have your professional confirmation. As you know, Josh Lederberg is extremely interested in considering the possibility of starting a new research program here in what might be called biochemical psychiatry--with emphasis, as you suggest, on the biochemical basis of disease. If you have any specific suggestions about research directions or, even more important, gifted younger investigators in this area, both Josh and I would like to chat with you about them. Best personal regards. Sincerely, Lost Rodney W. Nichols Executive Vice President ce: hocstaent Joshua Lederberg