8/4/86 MJ Barbara Bachmann Yale 8/2/86 Dear Barbara. E. coli genome size (I haven't followed this lately). Your 1983 map review allows 50 kb/min equals 5 x 10 to the 6th power base pairs. I thought DNA association kinetics had given a smaller number,? approximately 2 x 10 to the 6th power. Do I misrecollect? Do you know where this is most recently, critically discussed? Ditto for B. subtilis? Yours, Joshua.