j^j^Ct^ A NEW PHILOSOPHY OF MEDICAL SCIENCE, BASED UPON ANALYTICAL PRINCIPLES; .',& . THE CAUSE, SYMPTOMS AND TREATMENT OF THE MOST PREVALENT DISEASES. TO WHICH ARE APPENDED TESTS OF THEIR C By J. CLAW30N KEXiXiEir, Analytical Physician. « In Nature herself alone we mast expect to find the laws of Nature; and we pinnge into diffi. roltv and distress, only it proportion as we deviate from these Uws. To study Natnxe, therefor* f. to met tha part of a good subject, and of a friend to humauity."-^e Stunt Piert e. Neto=¥orft, J. A. FRA.ETAS & Co., PRINTERS—No. 7 SPRUCE-STREET. 1847. TO THE CITIZENS OF THE UNITED STATES. Fellow Citizens:—In the dedication of a work, professedly Medical, to our fellow-citizens of all classes, whether professional or non-pro- fessional, may be considered by some as supererogative and uncalled for—especially a subject which is pretty generally considered by per- sons out of the pale of the profession, as dark and mysterious—ab- struse and unintelligible—" stale and unprofitable." Many of our prudent Fellow-Citizens, who are contented with the old fabulous doctrine of medicine, founded on the grossest ignorance of the laws governing all animated nature—who settle down into the lethargy of contentment, at the suggestion that the "moon is made of the whole or part of a Yankee Cheese,u or the correctness that "man's origin was from a race of monkeys," will be perfectly satisfied to drag on at a snail's pace, well girdled in the harness of a fashionable superstition. To such in commiseration of their subservient views we have chosen to dedicate this Treatise. The more wise—the enquirers after truth—who adopt the maxim of reason before judgment—who are not 'so bound in fetters of the mind'— who are foremost in the support, encouragement and advancement IV TO THE CITIZENS OF THE UNITED STATES. of all that is useful in tending to the amelioration of suffering human- ity, promoting the spread of intelligence—overthrowing old and rotten edifices, (whose foundations are errors, and whose superstructures are prejudices) as so much useless lumber impeding the march of sci- ence—erecting and establishing upon a more firm and durable founda- tion, the TEMPLE OF TRUTH, around which her votaries may gather the many Chaplets of Fame, she so profusely spreads before them. To such, our dedication will meet with cordial welcome and respect. It has been the wish and endeavor of the Writer to simplify " hid' den mysteries^ in one of the grandest sciences—the brightest orb that ever studded the canopy of "Power and Knowledge"—to elevate from the level of a mere trade—to what it is justly entitled a humane and philanthropic science. He does not believe, that the technical jargon of the schools of medicine, enhances or elevates its scientific princi- ples, but on the contrary, retards all improvement and begets a detest- ed veneration for false and musty hypothesis, which will take years, if ever, of patient toil to blot from the Student's mind this mental hal- lucination. It needs no " spirit called from the vasty deep" to inform us, that a thorough and radical reformation in the now wm-called medical science, is most devoutly and ardently to be wished for—every one of our fel- low citizens who have passed through the ordeal of medical experiment, become pretty well convinced of the truth of this axiom. THE AUTHOR. » PRELIMINARY REMARKS. Medical Science is a department of Natural Philosophy. The ex- planation of the phenomena of life, of health, of diseases, of death, is only to be found in a knowledge of the operation of those general, uniform, immutable, physical laws, which govern and control univer- sal nature, in all its organic and its inorganic forms—in all its animate and its inanimate conditions. The true Theory of medical science is a knowledge of the opera- tions of those laws in the formation, support and changes of the hu- man system ; which pre-supposes a familiarity with the anatomical structure and functions of its various organs. The practice of medicine is the administration of such remedial agent, or the application of such remedial processes, as will remove whatever obstructions may retard the operation of the organic laws, or interfere with the necessirry actions, motions or changes of the animal frame. The human body is composed of various proximate principles or constituents, and these proximate principles are in their turn composed of two or more simple ingredients or ultimate elementary principles. Hence the human body is a chemical compound, and all the changes of its various solids and fluids, their decomposition and recomposition are affected by the operation of chemical laws. This view of'the subject has been objected to—that we cannot manufacture blood out of aliment in the chemical laboratory, and hence the argument in favor of a peculiar vital power is brought forward —But the objection fails—art may fail in imitating nature in her perfec- tions, although operating upon the same principles—and again, in rela- tion to the case in question, we have no such alembic as the human stomach in which to experiment, which sufficiently shows the futility of that objection. It is not the business of the student of nature to • 6 PRELIMINARY REMARKS. create the thing he professes to understand, his province is to ascertain those laws, or the modes of animal and vegetable existence ; their growth and decay. The undeniable truth that the human body is constituted of mate- rial substances, shows at once, that in seeking the true explanation of the modus operandi of medicine, they are to be found in the chemi- cal changes that matter produces upon matter, not in the " impres- sions," "sympathies," "vitalities," "energies," " excitabilities," "living principles," and such like metaphysical abstractions—which for ages have afforded the many votaries of medical science an ample field for imaginary theories, destitute of philosophy in which to build, rebuild, demolish, and redemolish system after system. Medical theorists in all ages seem to have taken it for granted that there was—that there necessarily must be something very pecu- liar—some incomprehensible principle, thing or being—separate and indistinct from either soul, body or spirit—that constituted the real and essential difference betwixt living and dead matter—betwixt ani- mate and inamimate—betwixt organic and inorganic substances.— They have also seemed to think that this peculiar principle must be a little better understood and its operations a little more cognizable to men's reason, before any fixed foundation could be laid for an endura- ble system of Medical Science—and thus while their time, talents and acquirements have been devoted to the vain pursuit of a phantom of their own imaginations, the whole legitimate field of science, left uncultivated, has run up to weeds, briers, thorns and thistles. To extirpate root and branch these " cumberers of the ground" and again to exhibit the*» fair field of science, inviting in its primitive beauty—rich in its innate treasures—and to direct thereto the ener- gies of the scientific'philanthropist, philosopher and physician, is per- haps no ordinary task. To direct general attention, research and in- vestigation to a new channel—to eradicate errors which have for ages been deeply rooted in the pride, prejudices or interests, of the learned the master spirits of an established philosophy—even the great oracles of science, requires time, perseverance and energy—nevertheless, as a world may accumulate around an atom, self-balanced in space—so may i PRELIMINARY REMARKS. 7 a little ball once set in motion eventually enlarge into an orb of sci- ence, which may ere long be seen revolving around the Sun of Truth. That some improvements ought to be made in medicine as well as all other arts and sciences,—that Medical Science is lamentably behind the intelligence of the age, is the well known conviction of all intelligent persons, professional or other. To be satisfied that the first principles of the Science of Medicine are not understood, a person has but to look around—see the various conflicting theories and practices in vogue—views—the various kinds of doctors every where prevalent, with the thousands, yea, tens of thousands of unintelligent doctors of the irregular trade, who are successful competitors with the Regular physician in the confidence of the people—in the procuring of patients, and even in (we say it with deep humility) the result of their prescriptions. New and useful improvements in other sciences—new applications of mechanical power, successful in their practical application to the pro- ductions of desirable and certain results in the necessary or useful pur- poses of human life, are daily springing up, giving a more energetic impulse to the general " onward march" towards final perfection.— The collateral departments of Medical Science, CherrVistry, Botany, Anatomy, Physiology, &c, are, too, cultivated and improved with a rapidity exceeding the most sanguine expectation, which their most confident votaries entertained but a few years since ; but that particu- lar department of philosophy, Medicine, is decidedly in the back ground. As a science, too, it is too uncertain in its results, too experi- mental in its practice, and too unintelligible in its theory. There is no general agreement between the authors of the various standard works upon the theory and practice of medicine, except in a general assent to what are called fundamental principles, and these are really fundamental errors. There is no general consistency or agreement between the theory advanced and the practice recommended by the same authors. Medical authors have too generally, in treating of the applicability of a given article of the materia medica for the treatment of a particular disease, adduced a host of reasons and authorities, both for and against the use of the article in question, which argument pro and con, too generally happen to be too nearly balanced for the practi- 8 PRELIMINARY REMARKS. tioner or student to draw any rational inferences, in relation to what is best to be done. The whole principles upon which the practice of Medicine depends, should be known by all—as familiarly understood by the man of gene- ral education, as the man of Medical education. It does not necessa- rily follow from this that all should be practitioners of medicine, or that the number of these should be either increased or diminished. There is no Science that is not as intelligible in its general prin- ciples to the non-professional as the professional man. If medicine is not an exception to all other Sciences in this respect, then it only follows that it is intelligible to nobody. Such is the eager spirit for the acquisition of knowledge upon all subjects, at the present day—and from the flood of light that has re- cently burst upon the world, from various departments of philosephy, that the spirit of enquiry must yet extend deeper and broader—that until men's understandings are fairly met and satisfied by medical philosophers—community will not—cannot place but a meagre measure of confidence in "legitimate medical science," and hence, until that is done, the'scientific practitioner must be content to " contend manfully for the faith ;" with the illiterate charlatan and the regular graduates of the " Institutes of Medicine" must come ifi almost daily competition with the self constituted M. D. of a patent nostrum. It is true, too true, that there is generally a repugnance in the pub- lic mind, to devoting any considerable attention to a subject, considered so abstruse as the theories of life, disease and health. This results in some degree from an ignorance of its momentous importance—yet in a much greater degree from the erroneous opinion that the whole know- edge pertaining to these subjects, which it is possible to possess must come through the routine of a professional education. If the rudiments of those sciences which are so intimately blended with the every day affairs of life—to wit: Anatomy, Physiology, Chemistry, Botany and Therapeutics, were made an essential part of a common school education, we should soon have, among all classes of community a multitude, (who now upon all medical subjects are mere automatons,) capable of making correct observations, of discrimi- nating betwixt science itself and scientific pretensions,—capable even PRELIMINARY REMARKS. 9 of making useful discoveries, in the amelioration of " the physical ills, that flesh is heir to," and the consequence of which would be, that, the present tendency to degeneration in human constitutions would be checked, and physical regeneration established. Another benefit that would necessarily accrue, and one of much importance, by submitting our scientific principles and pretensions to the judgment of the public mind, before we required the return of " faith in believing" would be the sure extinction of that innumerable race of medical advertisers, who now occupy so conspicuous a position in most of our otherwise readable papers and periodicals. % i-.,\*U. CHAPTER I. MEDICINE—ITS ORIG " In our researches," says Dr. Paris, " to discover and fix the period when remedies were first employed for the al- leviation of bodily suffering, we are soon lost in conjecture, or involved in fable —we are unable to reach the period in any country, where the inhabitants were destitute of medical resources, and we find among the most uncultivated, that medicine is cherished as a blessing, and practiced as an art by the inhabitants of New Holland and New Zealand, by those of Lapland and Greenland, North America and the interior of Africa.— Charms and amulets were the expedients of the Barbarians, ever more inclined to indulge in the delusive hope of super- stition than to listen to the voice of sober reason. Traces of 'amujets may be discovered in very early history; for Galen informs us that the Egyptian King, Nechetsus, who lived 630 years before the Christian era, had written that a green jasper, cut into the form of a dragon, surrounded by rays, if ap- plied externally, would strengthen the stomach and organs of digestion. We have moreover the authority of the scriptures in support of this opinion— for what were the ear-rings which Jacob buried beneath the Oak of Sachem, as related in Genesis, but amulets. Theo- Ehrastus pronounced Pericles insane, ecause he discovered that he wore an amulet about his neck." Medicine originated as a science by Hippocrates about 2000 years ago.— Previous to which time the people ap- pear to have been their own doctors, or advised with their priests. The arti- cles which they used were exclusively vegetable, and articles discovered by ac- cident They fortunately discovered, by pulverizing a certain root and taking a portion of it, it would act as a cathartic —by taking a tea made of a particular herb, it would produce perspiration, &c, The advantages derived from tbeir effects M AND SUPERSTITION. in disease, was not. only sufficient in- ducement for them to continue their use, but to acquire the effects of other plants. The cause by which they produced the effects they are known to do, they were unable to discover. They used them because they produced such effects, and the effects gave them relief. The Practice of Medicine by Hippo- crates, consisted in the collection of all those accidental discoveries which had then been accumulating for ages, and establishing a new branch of business by the erection of a " Doctor Shop" to sell and prescribe medicine. Hippocrates was equally ignorant of the cause, why cathartics, sudorifics or emetics produced the effec's which they are known to do —as much so as the most ignorant indi- vidual that preceded him—he only used them because they produced their par- ticular effects. The cause by which they produced their effects were as dark to him as the age in which he lived.— Hippocrates had acuteness enough to perceive his deficiency in this respect— he, was possessed of sufficient in- genuity to imagine or invent an expe- dient for this mystery—which should be as he fancied, and which has ever since been deemed a sufficient explanation of the mystery by every physician, theo- retical and physiological writer upon the science, since tbat day. The existing superstition of the people in the age ia which he flourished, were such as to favor an invention of this kind. It is a matter of some regret and surprise that scientific medical men of modern times are not less superstitious than the an- cients were in this respect. Hippocrates lived at a period which we now denominate the " dark ages."— The people at that time had no ideas of a Deity like those entertained at present. They believed in a plurality of Gods.— They believed that a specific deity was necessary and did preside over every 12 Medical Science. matter, circumstance and thing. Thus they had their God of strength—their God of wine—their Goddess of wisdom —their Goddess of spring, &c. When Hippocrates introduced the Practice of Medicine, if he had not even the dispo- sition, he could do no other than com- ply with the general and prevalent su- perstitious opinions; hence they insti- tuted a "God of Physic," deified him, and erected temples to him under the name of Esculapius. This Deity they contended governed the action of all medicine, by blessing or cursing it—ap- proving or disapproving of it. The only mode by which they could deter- mine whether it was pleased with an article administered as a medicine, was to try it on a patient; if it appeared to produce a good effect, it was received as evidence the deity was pleased with it —if an evident bad effect, the deity was displeased with it. In many cases they supposed the deity to bless a medicine given to one individual, and the same article administered to another, he would curse. But a short period however elapsed before other important offices were attributed to this specific deity — It was alleged, that it performed all the offices requisite to life; by first commu- nicating the living principle to every thing capable of life, either animal or vegetable; and afterwards sustaining it by its direct power and influence. Nor was this all; other important offices were again conferred upon it, that of performing all the offices of secretion and excretion. It was the direct cause of every involuntary action—through its agency the Mood was formed, the bile eecreted, the emunctories acted, the lungs inflated, the heart propelled the blood, &c. We here perceive Medical Science originating in the grossest and most ignorant superstition, and one most admirably calculated to not only obscure the science in the darkest mystery, but to place insurmountable obstructions to its improvements or advancement. Strange as it may appear to our rea- ders, that Medical Science should be founded in such gross superstition; yet is it not still far more remarkably strange, that the same chaiacterislic superstition yet governs every system of medicine now advocated, or yet offered to the world ?—the same principles yet do, and ever have governed the science! We admit that as the chamelion changes its color, so has this deity changed its name, to suit the character of the times ; yet the principles remain unaltered. Von Helmout called it archins; Cullen, vis medicatrix natura ; Darwin, sensoreal energy ; Rush, occult cause; Hooper, vital principle, &c. What it is, all agree it is impossible to tell! but they alledge, that it is neither material, nor immaterial; that it is neither matter nor spirit! All admit it to be an indefinable, incompre- \ hensible something! yet its existence and office, all alledge is not the least equivocal. Of its particular location in the system, there appears considerable disagreement. Some contend it is located in the stomach—some in the heart— some in the brain—some in the blood, and others that it is diffused throughout the fluids and solids. It will readily be perceived that whilst opinions of this character exist, the practice of medicine cannot possibly be other than experimental. All agents for the treatment of disease introduced into practice, must necessarily be the result of experiment. Hence in a case of dis- ease, we find regular, and those con- sidered well educated physicians, try this, then that, then something else; and at last are foiled in all their attempts at cure. Even if in their experimental practice, they administer an article which is attended with the most injurious results to a patient they have always a sufficient excuse—an ark of safety to flee to—a convenient scape goat in their vital principle or vis medicatrix natura ; and so will continue to have as long as they can render the belief prevalent, that an indefinable, incomprehensible something, separate and apart from the Laws of Nature, governs and superintends all the involuntary actions and motions of the Human Body. If this doctrine be true, why is not one physician as good as another ? And where is the use of any physician at all ? If all that we are to know is, that certain visible effects, Metallic Medicines. 13 as the cathartic effect of Jalap—the emet.c effect of Ipicacuanah,&c, with- out understanding how and why such effects are produced, where is the differ- ence between the most scientific doctor, and the most illiterate quack ? Does not the quack know by experiment that his pills will act as a cathartic, as well as the doctor knows about Jalap ? May not an article administered as an emetic or cathartic, have other actions than that which is visible, and that action be of the most injurious character ? Is it not so with Tartar Emetic and Mercury? It is lamentable that the whole Practice of Medicine of every sect and order, 1s based upon experiment alone, and that only. To entertain opinions like those ad- vocated and supported by the Medical Fraternity, we cannot! Because in the first place it pre-supposes that the great Jehovah, (who had power to form all worlds,) was so deficient in wisdom and power, as to be incapable of organizing and constituting laws, which would pro- duce organization and life ; and after- wards sustain it, without placing in the Human Body, a little indefinable some- thing to manage it! Again, we can never recognise the doctrine of an inferior deity usurping the Throne of a superior deity. Such principles can lead to no certain results in practice, it renders the practice empirical, experimental, guess, try, &c. In fact it is not worthy the appellation of a Science! CHAPTER II. METALLIC MEDICINES. 'Minerals excite a pernicious and baneful influence on the system; they seldom or never cure, bit often destroy the patient. Their operation is altogether uncertain, depending entirely on the state of the stomach, whether they act at all or are injurious."—Cooper'* Lexicon. Metallic Medicines were fir6t intro- duced into the treatment of disease in the 16th century by a sect called Alchemists, previous to which diseases were treated Principally with vegetable medicines. 'he Alchemists contended, that the ele- mentary principles of all matter, that is, the jirst principles of matter, whether in the' vegetable, animal or mineral king- doms, was salt, sulphur and mercury, and that in the animal kingdom, in these " three first substances," as they called them health and disease consist—that the mercury, in proportion to its vola- tility, produces tremors, mortification in the ligaments, madness, phrensy and delirium, and that fevers, phlegns and the jaundice are the offspring of the sul- phureous principle, while they supposed that the cholic, stone, gravel, gout and rheumatism, derive their origin from salt. The boasted champion of this system, was an individual styling himself "Theo- phrastus Bombastus Paracelsus " a native of Switzerland. He was the first that introduced mercury as an internal remedy for the cure of disease—he was a most daring and illiterate quack, as well as a most notorious drunkard and de- bauchee. Owing to its deleterious effects, it produced among the medical world considerable excitement, and for 200 years, there was a great struggle between the followers of the vegetable practice, the then prevailing treatment, which finally, through the intrigue and sophis- try of the Alchemists, the vegetable sys- tem was overthrown, and the mineral system established.—The term QUACK was applied by the advocates of the vegetable treatment, to all who used quacksalber or mercury, and certainly they still deserve that title. Mercury has become so universal a remedy for disease, that the amount of the many years spent by the student, in poring over books, anil lectures, is but mercury and bleeding. On every trifling occasion, mercury or blue pill is given, 14 Metallic Medicines. and thankful should that individual be, who hapily escapes its destructive effects. Even among the mineral physicians, we find some, who speak in strong lan- guage against it; Dr. James Hamilton, professor in the University of Edinburg, observes, " that there are but few poi- sons more active, or more dangerous, and so deleterious is it, that even the smallest dose of it, may speedily destroy life." Dr. Reese, of London, makes the follow- ing confession—" we know not," says he, " whether we have most reason to bail the discovery of mercury as a bless- ing, or regard it as a curse, since the diseases it entails, are as numerous as those which it cures." An American Physician, states, that in using mercury in fevers, it has removed the fever, and the patient to all appearance is in a state of convalescence, when suddenly, he is attacked with another fever, the mercu- rial fever, by which the patient loses his life, often before the physician can reach the house. Dr. Falconer, mentions, that it produces tremors, paralysis, and often incurable mania. Scrofula and cancer are aggravated by it, and it produces diseases, particularly among sailors, and inhabitants of south- ern climates, of which, the most respec- table practitioners, are ignorant, together with the means of affording relief. Wit- ness the pains and diseases to which southern people are subject, or visit the hospitals for seamen, and observe the poor sailors, crippled or injured in some manner for life by i«s use. The use of it produces impaired or capricious appetite for food, indigestion, flatulency, disturbed sleep, frightful dreams, impaired or depraved vision, frequent aches and pains in different parts of the body—as the kidneys, liver breasts, limbs, sides, &c.; sometimes a Budden failure of strength, as if just dy- ing—violent palpitations of the heart, difficulty of breathing, emaciation, debi- lity, eruptions of the skin, sore throat, piles, ulcers, palsy, fatuity, epilepsy, dropsy, nervous affections, decay of the bones, rheumatism, and the mercurial disease—salivation is produced, the breath becomes foetid, teeth rot and fall out, and often the whole jaw, the hairs fall off or turn prematurely gray, the countenance is sallow, and the individu- al suffers numerous pains. " It is true," 6ays a distinguished wri- ter, " all patients are not killed who take it; but it so retards the efforts of nature to remove this poison, and the disease together, from the system, that she often struggles " like a cart beneath the sheaves" to effect it, and very fre- quently if the constitution is not suffi- ciently strong, it kills the patient almost immediately or at some subsequent pe- riod ; or if it does not have this effect, it renders him a cripple, or miserable for life, and perhaps it would be much bet- ter for hiin, if the physician had imme- diately put an end to his life by a dose of Arsenic or Prussic Acid; for in this case, the constant state of torture, misery and wretchedness, which attends the exhibi- tion of this mineral, would be avoided. It penetrates into every avenue of 1he system, destroying the flesh, bones, fluids and mental powers. The person who takes it is liable to have his teeth drop out, his tongue inflamed or ulcera- ted, and perhaps protruding from his mouth,his flesh wasted away, saliva and blood flowing copiously from bis mouth and gums', or perhaps the whole jaw-bone in a state of rottenness or exfoliation; the patient is unable to chew or swallow; such a stench arises from his breath, that his friends or attendants can scarcely ap- proach his bed-side; he is scarcely able to articulate a word; his stomach and bowels deranged; flesh and strength gone ; he is'racked and tossed with ex- crutiating pains, unable to sleep or deli- rious ; and the poor patient is now doomed to sink to an unlimely grave, a victim of quackery, empiricism or charla- tanism; and should the unfortunate be- ing recover from the immediate effects of 6uch worse than barbarous treatment, he is doomed to drag out a miserable exis- tence ; and all from the use of the dead- ly poison administered under the garb of medicine. A preparation or agent, which I never could learn, was ever capable of curing a disease, any further than arises from its action as a purga- tive." Metallic Medicines. 15 A medical writer observes, "it is a matter of profound astonishment to me, that any article productive of such dele- terious effects, should be so highly ex- tolled by the faculty, and be so univer- sally used." Dr. Henstis, an American physician states, '«1 have known and seen many cases of salivation in bilious fever, but never have I known an instance where- in I had not every reason to believe that the recovery was thereby retarded. It is certain that patients often recover, who have been salivated in this disease ; and this, strange as it may appear, has afforded an argument for the advocates of this medicine, to say and to boast, that the cure was effected by mercury, where- as, the probability is, that had the pa- tient never tasted the article, or experi- enced its effects, his recovery would have been much more rapid. The unfortu- nate instances of the failure of a sali- vation in the cure of fever, are too nu- merous to leave any doubts as to Its pernicious and destructive effects. The horrid spectacles frequently to be seen, as the consequences of the mercurial treatment, are shocking to humanity, and disgraceful to the profession. Even were mercury the only alternative, that life is dearly purchased, which is bought at the sacrifice of every thing that ren- ders life desirable ; the constitution bro- ken and destroyed ; the person maimed and disfigured, so that it is scarcely re- cognized by the unfortunate sufferer himself ; an object of pity and horror to his friends. Deprived of their teeth, and perhaps their jaws ;"we sometimes see these pitiable objects, with distorted features, the jaws, cheeks and palate having been partially destroyed by mor- tification, and the remaining portion cic- atrized, (healed) into an unsightly knot with the mouth distorted from its natu- ral position, and drawn obliquely to- wards the ear, and the lips and cheeks consolidated with the gums. It may be said in reply, that such effects seldom occur from a salivation, yet they sometimes happen, and rarely does it fail that the constitution escapes from the salivation without sustaining a last- ing injury. Were it always in the power of the practitioner to coatrol the opera- tion of mercury, less danger would be sustained or apprehended from it; but unfortunately this is not the case. Calo- omel is often given to a great extent during the continuance of fever without producing'any sensible effects, and it is only after the solution of the disease, when convalescence isabout taking place that this latent poison breaks forth with ten-fold violence. The patient, who about a day or two previously, flattered himself with a speedy recovery, now finds himself sadly disappointed, and is doomed to undergo a factitious disease, more tedious and painful than the first." It is a lamentable fact, that physicians have been, as is justly observed by the author of Lacon, " tinkering the consti- tution for upwards of 2000 years to cure disease, and the result of all their discoveries is, that Brimstone and Mer- cury are their only specifics, and diseases remain what they ever were." And yet they have been unable to discover the mode of operation of any one prepara- tion of Mercury; in their works upon the subject they say, " it is in vain to enquire," " it has a peculiar action upon the vital functions." " Of the modus operandi of Mercury we know nothing.* Knowing its destructive effects, we cannot too strongly warn the public against its use, and that class of practi- tioners who are in the habit of prescrib- ing it; if they value their health, or that of their offspring; if there is a spark of that benevolent, human, merciful feeling towards their fellow citizens, a desire to see the sufferings of mankind lessened, let them cherish it as they would a gem of inappreciable value, and beware of that bane to man, mercury. And that individual who knowing its deleterious effects, still persists in using it, deserves no pity, no sorrow for his miserable sit- uation, and his physician no censure for what he has done. Mercury is called the Sampson of the Materia Medica, and so it appears to be; for if Sampson slayed his Thousands, this mineral has slain its Tens of Thousands. ARSENIC, (from the Arabic term Arsanek, from its strong and deadly * For a full explanation of its mode of action, See our'late work en titled " Key to Medical Sci- ence." —page 187. 16 Metallic Medicines. powers.) The first account we have of this metal is to be found in the writings of Dioscorides,and of some other authors who wrote about the beginning of the christian era. It is the same substance which Aristotle had called " Sandara- cha," which was used by the ancients in the arts. The White Oxide of Arsenic, or what is generally understood as Arsenic, is spoken of in the writings of Avicenna in the 11th century. At what period the metal called Arsenic was first extracted from the Oxide is unknown. Paracel- sus knew it, and the manner of obtain- ing it is described by Schroeder in his pharmaccepia published in 1647. It was not until 1733 that this metal was ex- amined with any degree of Chemical pre- cision. This metal is capable of combining with two doses of oxygen, and of form- ing two compounds which possess acid properties, and which have been denom- inated Arsenic and Arsenious acid. Arsenious Acid, White Arsenic, Ox- ide of Arsenic and Rafs-bane, are one and the same article—and is that which is generally used for remedial purposes. The particular period in which it was first introduced is not known, but it has been supposed to have originaed with the Alchemists. It is prescribed by physicians of mod- ern times for the following diseases, Can- cer, Ulcers, Intermittent Fever, Chronic Rheumatism, Diseases of the Bones, Neuralgia, &c. Arsenic is one of the most deadly me- tallic preparations to both animal and vegetable life—Dr. Hooper in his Medi- cal Dictionary pronounces it one of the most sudden and violent poisons with which we are acquainted ; and even when the quantity given, is so small as not to prove fatal, it produces tremors, paralysis and lingering hectics. On the combined testimony and experience of many practitioners, we unhesitatingly condemn the use of it as a medicine. The revolting spectacles of its noxious qualities are witnessed in the unfortu- nates who have been subjected to its powerful influence in the western parts of our country, where it is dealt out by the practitioner with a liberal hand as a nostrum in Ague and Fever. Mr. Bran- de states that he " considers that its in- troduction into the pharmaccepias as a great evil; as more harm than benefit has resulted from its administration."— " The Oxide of Arsenic," says Dr. Eberle, " acts with great violence when taken internally,and commonly destroys life in a very short time"—and continues he, in a dose of " one fourth of a grain, it excites nausea and slight chills. By continuing it in such doses, it destroys the appetite, excites vomiting, pains in the stomach and bowels, painful diarr- hoea, great anxiety and oppression in the breast, debility and emaciation, numb- ness of the hands and feet, dropsical swellings, tremor and paralysis. From the statement of Dr. Paris, it is both de- structive to animal and vegetable life, that the influence of the Arsenical vapours near the copper smelting works of Cornwall and Wales " is very appar- ent in the condition both of the animals and vegetables in the vicinity." From the observations of M. Jaeger, it ap- pears that " the death of vegetables is induced by Arsenic from the gradual ab- sorption and distribution of the poison by the vessels and cellular membrane, so that the plants die in succession as the particles of the Arsenic reach them." The following terrible effects attend- ing the administration of Arsenic is de- scribed by Orfila—" An austere taste in the mouth ; frequent ptyalism ;* contin- ual spitting; constriction of the pha- rynxf and acesophagus ;% teeth set on edge; hiccups; nausea; vomiting of brown or bloody matter ; anxiety ; fre- quent fainting fits ; burning heat at the precordial inflammation of the lips, tongue, palate, throat and stomach ; acute pain of stomach, rendering the mildest drinks intolerable; black stools of indescribable fcetor, pulse frequent, oppressed and irregular, sometimes slow and unequal; palpitation of heart; syn- " Salivation, t The muscular bag at the back part of the month. t The tube that carries the food into the sto- mach. i The foropart of the region of the chest. Metallic Medicines. 17 cope ;* undistinguishable thirst; burning sensation over the whole body resem- bling a consuming fire; at times an icy coldness; scanty urine, of a red or bloody appearance—altered expression of coun- tenance ; a livid circle around the eye- lids ; swelling and itching of the whole body, which becomes covered with livid spots, or with a miliary eruption, pros- tration of strength, loss of feeling, espe- cially in the feet and hands; delirium convulsions, sometimes accompanied with an insupportable priapism ; loss of the hair; separation of the epidermis ;f horrible convulsions and death. ANTIMONY", and its different prepara- tions, as Oxide of Antimony, Tartar Emetic, Tartar Emetic Ointment, James' Powder &c. Theancients were acquainted with this metal. Pliny informs us that it was found in silver ore. It generally contains a portion of Arsenic. Basil Valentine, a German Monk is the first who describes the process of extracting it from the ore. He by the internal administration of it, (although unintentionally it appears,) poisoned his brother Monks; hence its present name, Antimony, or Anti-Monk. No metal, not even Mercury, has at- tracted so much the attention of physi- cians—one party extolling it as an infalli- ble specific in every disease; while anoth- er derided it as a most virulent poison which ought to be expunged from the list of medicine. It appears that Paracelsus, who it seems had an itching for dabbling in nearly all the metallic medicines, was one of its warmest advocates, and recommended it as a sovereign remedy in the Plague that raged with considerable violence at Bohe- mia, in 1562. Instead, however, of its proving itself a valuable specific in this disease, its administration was on the contrary productive of the most danger- ous consequences, and was denounced by the Medical Faculty of Paris as a fatal poison; the consequence of which, the French Parliament issued a severe decree against its internal employment in 1566. All the oxides of Antimony are some- * Fainting or swooning. t The skin. what soluble in water; in this respect it resembles the oxide of Arsenic in ap- proaching an acid state. Antimony iscapable of combining with Oxygen, and forming an acid called anti- monious acid. By the addition of Cream of Tartar to Antimony, in boiling water tartarized Antimony or tartar emetic is formed. Cream of Tartar is composed of Potas and tartaric acid, and hence the true character of Tartar Emetic is tartrate of Antimony and Potas. The taste of Tartar emetic is nauseous and caustic. In this form it is made use of in medicine, sometimes by uniting it with some nausea- ting plant, at other times dissolving it in water and giving the patient small qunti- ties at a time, as in table spoonful doses, until the emetic effect is produced. Tar- tar emetic when rubbed with lard forms tartar emetic Ointmeut—used for rubbing over the chest for the purpose of produc- ing pustules and eruptions on the skin. It is also used combined with Mercury, Sulphur, and with Lime in the nostrum called James' Fever Powder. Antimony, when taken internally, pro- duces sickness of the stomach, vertigo, anxiety, insensibility and delirium. The experiments of Brodie on living animals, with this metal, produces paralysis, insen- sibility and loss of the power of motion. On opening them he found the pulsation of the heart exceedingly weak, and al- though artificial respiration was kept up, it soon ceased to act. Tartarized Antimony or the oxyde of Antimony, both being soluble are as ca- pable of being absorbed in the system as Mercury, and extending its destructive, irritating and poisonous influence to every organ, which is plainly evinced by its ac- tion on the system, in cases where its ef- fects become obvious, which are an aus- tere metallic taste in the mouth, nausea, copious vomiting, hiccough, burning pain in the stomach, cholic, frequent evacua- tions from the bowels of a slimy and blue appearance often tinged with blood, faint- ing, small, contracted and accelerated pulse, surface of the body cold with clammy sweats, burning inward fever, intense thirst, difficult respiration, loss of sense, convulsive movements, very painful cramps, prostration and death. 18 Metallic Medicines. Where these dreadful effects do not fol- low its use, it is capable of being decom- posed by the various fluids, constituents of the human body and they in becoming acrM, poison the .solids, at the same lime depriving them of the requisite degree of material to supply their important changes and growth. The most serious and de- plorable consequences follow this course of treatment. The most important fluids of the human body become decomposed, changing their composition from that of healthy to the most fatal or deleterious venom, to wit, the bile, the nervous and glandular fluids, and even the blood itself. Look at the blue livid appearance of the skin and its dead and inactive state where this metallic poison has been used as in fevers, pulmonary and bronchial affections —That many dyspeptic complaints are produced by its use there is little doubt; as it even decomposes the gastric juice, producing gastritis, attended with hic- cough, a burning and gnawing sensation is felt in the stomach, belching of acrid and caustic liquor and frequent ineffectual attempts at vomiting. Orhla, on poisons, makes the following remarks on the effects of antimonial pre- parations, " It is to be remarked that these preparations, more particularly oc- casion copious and obstinate vomiting, large evacuations by stool, great difficulty of breathing, and such a constriction of the throat, that the patient is unable to swallow any thing, finally very painful cramps, a sort of intoxication, and amore or less considerable prostration of the vital forces." Consumption, all diseases of the lungs, are aggravated by antimonial preparations yea, in many cases it produces consump- tion M. Gerard, an European Physician, states, that " its internal use, sometimes roduces pustules, occupying considera- le portion of the intestinal canal, simi- lar to those produced on the skin by its application." Another Medical writer ob- serves, that when given even in doses of' a few grains, he has known it to produce sudden, dangerous, and fatal collapses, and a persisting and uncontrolable cath- arsis, in consequence of the enythema and irritation excited in the mucous sur- face of the stomach an.I intestines. Dr. Heustie. says, " perhaps there is no medicine in the catalogue of the Materia Medica that has been productive of such opposite effects as this; at one lime when exhibited under iavorable circumstances, putting a stop to the progress of the dis- ease at the very threshold; and at another, precipitating the patient hastily into the arms of death. As far as my observation extends, I think I am warranted in say- ing, that tartar emetic can never be pru- dently exhibited in the hiszh and malig- nant grades of bilious fever. I am con- firmed in this opinion from having seen and known so many instances of alarm- ing, and sometimes fatal prostration, pro- duced by its exhibition; I have known persons in a high fever, with a strong and fall pulse, and generally increased tem- perature of the body, in less than two- hours after taking this poisonous medi- cine, to be affected with a death-like cold- ness ; the pulse at the wrist no longer per- ceptible, the eye inanimate, the lips, cheeks and extremities, exhibiting the !iv- idity of death, a cold and copious sweat exuding from the general surface of the body and every symptom of approaching dissolution." SILVER—Nitrate of Silver, or Lunar Caustic, Filings of Silver, Nitrate of Silver Pills, &c. At what period this metal was discov- ered and who recommended it as an in- ternal or external remedial agent in dis- ease is not known—it is probable that it was known as early as Gold, which has been supposed to have been the first metal employed by man. The first authentic account we have of its being prescribed and recommended as a medicine, is to be found in the writings of Bombastus Para- celsus and " Vitalisl" Stahl who speak of it as a specific in epilepsy. Nitrate of Silver is highly extolled by the mineralists as one of the most valua- ble Metallic tonics in the whole of their Materia Medica. None of the metallic preparations has received so high eulo- giums as this, from Paracelsus, Stahl, Simms, Cappe, Nord, Roget, Powell, Metallic Medicinei. 19 Brurse, Thacher, Eberle and other lumi- naries of the mineral practice in diseases of Epilepsy, Mania, Tumors and " sym- pathetic" palpitations of the heart; St. Vitus' Dance, Dropsy, Fluor Albus, Scro- fula, Mercurial disease ; Diseases produ- ced by the adminstration of Lead; In- flammation of the mucous membrane of the stomach, bowels, &c. &c. Nitrate of Silver is composed of Nitric Acid and Silver, and is one of the most irritating and corrosive metallic poisons. It is more generally known under the name of Lunar Caustic, an outward ap- plication to warts, fungus flesh, &c. as an eating and burning substance. It is alsoJYequently administered internally in the form of Pills, combined with some powerful narcotic in order in a measure to destroy sensibility of the nervous power, that the sceptic effects of the metal may not be so sensibly felt. " Nitrate of Silver" says the U. S. Dis- pensatory, " produces the effects of the corrosive poisons." " Caution must be exercised not to continue it too long, as it is apt to weaken the stomach." '* In epilepsy it has gained some celebrity as a remedy ; but, though sometimes benefi- cial, it often fails. Its effects have been found to be most favorable in this disease when it acts upon ihe bowels." (!) Sementini, an Italian physician, says, " that a cutaneous eruption of a pustular kind, frequently appears in those who are taking this remedy; and that when this takes place, we may be assured of the beneficial influence of the medi- cine."^) " In my own practice," adds Dr. Eberle, " It has but very seldom proJuced any decided advantages, although I have giv- en it largely and persevering I y in several instances. He also adds, that it is now ascertained beyond a doubt, that the long continued use of Nitrate of Silver is ca- pable of giving a permanent black color to the skin." GOLD—and its preparations, as Muriate of Gold, Oxide of Gold, &c. Gold seems to have been known from the earliest period, and valued highly by all races of men, owing perhaps in a great measure to its scarcity and beauty. During the tirade of the alchemists against the vegetable treatment, this me- tal which they ridiculously contended they could manufacture out of the baser metals, as lead, copper, &c, was held by them as sovereign in its effects as a medicine ; but owing to its deleterious nature as a remedial agent, it soon fell into disrepute. It was not until 1810, that it was again brought forward by Dr. Chrestien of Montellier, who published a treatise upon it extolling it as a remedy in Scrofulous and Syphilitic diseases. Gold in any of its preparations when administered, produces inflammation of the whole system which is rapidly fol- lowed by ulceration of the stomach and bowels terminating in death. Orfila ranks the Muriate of Gold among the most poi- sonous substances. Chrestien asserts that it is incomparably stronger than Corrosive Sublimate. He administered it in doses, at first no larger than one fifteenth of a grain, and if pushed beyond one tenth of a grain, it never failed to excite fever and inflammatory symptoms. " Pontin and several Swedish physicians, who have tried this remedy, state that they never obtained any real advantage from its use." The U. S. Dispensatory says. •« The pre- parations of Gold are decidedly poison- ous, though indifferent degrees." A work entitled " Quacks and Quackery," writ- ten in support of the mineral system, has the honesty to say that it is one of the most corrosive and irritating poisons and soon causes death. COPPER—and its preparations, as Blue Vitriol, amonialed Copper, acetate of Copper, (Verdigris) " If we except Gold and Silver, Copper seems to have been more early known than any other metal. In the "first ages of the world, before the method of work- ing iron was discovered, Copper was the principal ingredient in all domestic uten- sils and instruments of war. Even dur- ing the Trojan war as we learn from Ho- mer, the combatants had no other armor but what was made of bronze; which is a mixture of Copper and Tin. The word Copper is derived from the island of Cy- prus, where it was fir3t discovered, or so Metallic Medicines. least wrought to any extent by the Greeks." When any of the preparations of Cop- per are taken internally they produce a copperish taste in the mouth ; nausea and vomiting : violent pain in the stomach and bowels; frequent black and bloody stools; small irregular, sharp, and frequent pulse; fainting; burning thirst: difficulty of breathing; cold clammy sweats ; small quantity of urine; violent head-ache; cramps, convulsions and death. Who first introduced it as a medicine is not known. ZINC—Oxide of Zinc, &c. The preparation called Oxide of Zinc was introduced by Gaubius, who obtain- ed his knowledge of its " remediate powers from a celebrated quack." Its action upon the system is violent, producing vomiting, spasms of the sto- mach, constipation or diarrhoea, inflam- mation of the bowels, convulsions and paralysis. It is given in Epilepsy, Worms, Chronic Histeria, Cutaneous Eruptions, Spasmodic Asthma and Small Pox. BISMUTH—Oxide of Bismuth. This metallic Oxide was introduced into practice by Dr. Odier of Geneva. Its ac- tion upon the system is similartotheOxide of Zinc; as alarming distress in the sto- mach, nausea, vomiting, diarrhoea or con- stipation, colic, heat in the breast, vertigo, drowsiness and death. It is recommend- ed in epilepsy, palpitations of the heart, and spasmodic diseases. LEAD—Sugar of Lead. Carbonate of Lead, Red Oxide of Lead, &c The U. S. Dispensatory states—" when introduced into the system byimpercepti- ble degrees, it acts injuriously on the nervous system, producing a peculiar colic, called lead colic and palsy, which is at most, always partial and incomplete. Dr. A. J. Thompson, of London, states, " that of all the ordinary preparations of lead, the carbonate is the most virulent— and that those Salts which are easily convertible into the carbonate are also highly poisonous." Sugai of Lead is an irritant poison—its use produce--* violent pains in the bowels and obstinate consti- pation called lead colic, affecting the mus- cles, depriving them of their support, as witnessed in those who work in lead or have been subjected to its influence. Carbonate of Lead is most generally used as an external application to ulcers and to inflamed surfaces and is capable of being absorbed into the circulation produ- cing the above poisonous effects. Acetate, or Sugar of Lead is the form in which the mineral physicians usually prescribe internally in bleeding of the lungs intestines and uterus; Dysentery, Cholera of children, in checking vomiting, &c. notwithstanding these mineralists, who recommend it so highly in disease, speak in the strongest terms of its prison- ous and deleterious effects upon the hu- man system—Sage consistency this, tru- ly ! They say, to use the language of the U. S. Dispensatory, "it acts as an irritant poison, producing inflammation of the ali- mentary canal, if the patient survives for some time !" IRON—The preparations of Iron are numerous, amounting to upwards of 20 different kinds; they are prescribed in general debility and " relaxation of fibre" and languid circulation—in diseases of hysteria, fluor albus, gleet, scrofula, rick- ets, St. Vitus' dance, Palsy, Dyspepsia, Neuralgia, &c. Its use produces heat, thirst, headache, difficulty of breathing, and other distres- sing effects. Professor Liebeg of the University of Giessen, in his work on Organic Chemis- try, says, " The true Organic poisons are those articles which possess the power to form fixed permanent compounds with the muscular fibres and membranes, salts of lead, Bismuth, Copper, Mercury and Iron are of this class." For remedial purposes, the preparations are usually conjoined with other tonic or alterative articles, as Myrrh, Gentian, Al- kalies or Acids which are really benefi- cial without any deleterious consequences and all the permanent benefit accruing, we are disposed to impute to these adjuvants, we freely admit that a transient stimulus with increased digestive power and ner- vous energy results from iron alone. But those who notice closely the effects of a long continued use of the preparations of Vegetables and their poisonous properties. 21 iron, will discover eventually that the florid flush of the face, the increased heat ofthe6urface, the mental energy &c, will gradually decline under their continued use, an increased irritability of the various organs, with general debility .will super- vene, so much so, that often the patient cannot bear any article of a bracing nature at all—the florid cheeks will become pal- lid or an excessive unhealthy crimson or hecticflush, and the surface preternatural- ly sensitive to alterations of heat and cold —the secretions again either deficient in quantity or impeifect in quality—while all attempts to lessen these conditions by a farther use of any preparations of iron will be fruitless. The many virtues of Mineral Water, which contain a small portion ot iron can very well be explained without con- ceding any remediate agency to any min- eral whatever. The Muriate of Soda and Carbonate of Soda, as well as several other non-mineral ingredients, which they contain are useful medicinal articles, which connected with " scenery" and sal- utary exercise, often prove serviceable to the invalid. For a more extended analy- sis of the action of the preparations of iron we refer to our work entitled " Philo- sophical Medical Journal." We here close our Chapter on " Metallic Medi- cines." Fellow Countrymen, we know the above statements to be facts, glaring be- fore you, will you rest contented to suf- fer, or will you arouse to a man, as free- men, and tell the monopolizing faculty that you will be trifled with no longer that you are done with poisonous and ar. tiiicial remedies and will use only those which will act in harmony with the laws of your existence—and we promise in re- turn, that your wives, your children, even your countrymen will suffer less sickness, less debility, live to a more advanced age, and enjoy a state of mind and body, calculated to render the sweets and plea- sures of a freeman's life worth the liv- ing for. CHAPTER III. VEGETABLES AND THEIR POISONOUS PROPERTIES. Though we are of that class of prac- titioners of medicine who repudiate the use of metallics, either in their simple or combined state as remedial agents in the treatment of diseases, and contend that the true medicinal substances are only to be found in the vegetable kingdom. Yet, we are free to admit that there are many vegetablesjwhich contain substances poi- sonous, even in their minutes' doses, »o the animal economy ; and which we con- tend do not contain any remedial proper- ties whatever. That vegetable agents are the only proper remedies for the treatment of dis- eases, no one who understands the phi- losophy of vegetable and animal matter will attempt to deny. What is animal matter but a concentration of the proper- ties of vegetable matter ? Yet this may be met by the graduates of the Metallic In- stitutes of Medicine, with the assertion, we say " assertion," for we defy them to prove the truth of it, that vegetable and animal matter contain metallic substances. To such we would say, name to us the vegetable that contains Mercury, Arsenic, Antimony, Lead, Copper, Iron, Silver, Bismuth, or any metal whatever ? Can vegetation exist and be supported in a me- tallic bed? Such stupidity of reasoning on the part of the infatuated physician, shows a want of information of the laws and grades of matter. Prussic Acid stands at the head of ve- getable poisons—one drop of this acid, placed upon the eye of a dog will prove instantaneously fatal—the act'on of this acid is strictly confined to the nervous system, neutralizing the fluid by which their power of action becomes perfectly paralised and death results. Hufeland relates, that a man about to be taken up as a thief, took Prussic acid, 22 Vegetables and their poisonous properties. staggered a few steps and fell. The pulse could not be felt, and there was no trace of breathing. In a few minutes there was a single violent expiration. Orfila states, that a servant girl swal- lowed a small glassful of Alcohol satura- ted with Prussic acid. In two minutes she fell dead. Beck states, that a Chemist in Paris ap- plied a bottie of the acid to his nose, afarming symptoms immediately com- menced and continued throughout the day. IODINE,—This vegetable salt was first discovered in 1812, by Courtois, a soda manufacturer of Paris. It is a constituent of many marine plants ; as the common sea weeds, &c, of sponge, oysters; in sea water, salt springs ; in many springs at Saratoga, &c. Iodine was first used and recommend- ed as a medicine, by Dr. Coindet, of Ge- neva, who employed it in bronchocelle'.* This article is used both internally and externally, in the form of Ointment, So- lution, Tincture, &c. Recommended for enlargement of the glands of the breast; of the Liver and Spleen ; Cancer, Vene- real Complaints, Ulcers; Ovarian Dropsy, Leprosy, Pulmonary Consumption, Scro- fula, Gout, White Swelling, Deafness, Fistula.Distortionsof the Spine, Piles, &c. It is observed by Breza, " that like mercury, iodine maintains a permanent action on the system, for a considerable time after its administration has been sus- pended." Coindet gives the following description of the action of iodine. " Highly accel- erated pulse, palpitation, frequent dry cough, great loss of strength and emacia- tion, swelling and tremors of the lower extremities, wasting of the mama* and a continued and annoying increase or ap- petite." Dr. Eberle states, " certain individuals can never take it in doses sufficient to af- fect the constitution without very unplea- sant consequences; such as dimness of vision, indistinct hearing, fallacious touch and various other nervous symptoms." In some individuals iodine produces a * A tumour on the fere part of the neck, and seat- ed between the wind-pipe and skin. * The breast. peculiar itching or tingling sensation oyer the whole surface of the body; and its external application in the form of oint- ment, is said sometimes to cause a total loss of sensation in that part of the integ- uments on which it is rubbed, extending itself occasionally to those parts which are supplied by the same nerve3 of sen- sation." SULPHATE of QUINIA. This salt is obtained from Peruvian Bark, by means of sulphuric acid. It is recommen- ded and lavishly prescribed in intermitting fevers. Experience has shown its ad- ministration in many cases to have proved deleterious and dangerous to the system ; to prove which we only have to cast our eyes over the pages of those who have written on the subject of Quinia, when we find the author highly extolling its virtues in one paragraph to be condemned in the next. Thus it is with Dr. Eberle upon the virtues of this article. " Experience" says he, " has indeed established its excellent powers as a rem- edy in intermitting levers and other anala- ogous periodical affections, usually treated by tonics." Again, "Occasionally, this preparation acts strongly upon the ali- mentary canal, producing violent purging or vomiting," And again, the same au- thor observes. " A full dose is usually followed by a manifest increase of the temperature of the surface, and a feeling of tension and fullness in the head. Its tendency to determine the blood to the brain, is indeed very considerable. When full and frequent doses are taken, the countenance generally becomes flushed, and the vessels of the head turgid, attend- ed with a sense of confusion, heaviness of the head, and often ringing in «he ears. In three instances under my obser- vation, the cerebral congestion produced by this article, was so violent as to give rise to a singular form of delirium, re- sembling the mental derangement which is excited by an over dose of Strammo- nium." To this catalogue of morbid symptoms produced by the use of this drug, we might add, without over-stepping the bounds of truth, which many can bear witness who have been subjected to " full Bleeding. 23 and frequent doses" of Qninia in fever got or spurred Rye, Extract of Hemlock, and ague; swelling or enlarging of the Opium, Morphine, and all the prepara- liver and spleen—the bile becomes acrid tions of Opium, &c &c, and depraved—nervous system deranged The vegetables which are devoid of all —watery state of the blood, terminating useful medicinal qualities and which are in dropsy and death. highly destructive to animal life, are There are many other poisonous pre- deadly Nightshade, Henbane or Hyosy- parations and extracts that are obtained amus; Hemlock, or sometimes called poi- from the vegetable kingdom, which son Hemlock ; Nux Vomica; Thorn Ap- should never be prescribed as medicine, pie or James Town Weed, Digitalis, or as Croton Oil, Oil of Tansey, Hydriodate Fox Glove ; Bitter Almonds, &c. &c. of Potassa, Oxalic Acid, Oil of Savin, Er- CHAPTER IV. MEANS RESORTED TO IN THE TREATMENT OF DISEASES WHICH ARE MECHANICAL IN THEIR APPLICATION. BLEEDING—Has long been practi- brane: is there no other mode of relief sed : even so early as the time of Hippo- but blood-leiting ? Can no course be crates. He bled his patients to excess, adopted to equalize the circulation ? Are sometimes opening two veins at once, there no attenuants—no refrigerants—no and frequently suffering the blood to flow rubefacients ? Cannotthe blood be induced to such an extent as to produce fainting, to leave the part? The practice of modern physicians is not The manner in which disease is over- so frequently carried to such an extent as come by bleeding, is by debilitating the to produce fainting; but the operation is system so far as to deprive it of its pow- oftener repeated. In inflammation of the er of action. Yet the disease is not there- lungs, liver, kidneys, &c. recourse is im- by cured; it is only changed from an mediately had to bleeding. For what acute to a chronic, fixing itself upon some purpose ? To lessen the inflammatory ac- internal organ, as the liver or lungs; and tion of the affected part—to relieve the should the patient eventually recover, he pain, or difficulty of breathing, as the owes it to the kindness of some good case may be. Does it relieve? Certainly : dame, nurse, and his constitution alone. In many cases it does. How ? By lessen- The assertion that bleeding is requisite ing the quantity of blood, by which in consequence of a surplus quantity of means the force of the circulation is re- blood, termed " plethoric state of the sys- duced ; the vessels become less distended, tern," " a fullness of habit of body,"&c, and the pain thereby mitigated. How is untenable and cannot be maintained or long ere the same operation is required supported. to be repeated ? But a few hours and it Blood can only be produced in propor- requires repetition. What must be the tion to the food we use, and if in a heal- effect, if every few hours blood be drawn thy state must constantly make its depo- from a healthy, robust person, would not sites throughout the system, and the re- the system become exhausted ? Must not suit that must follow, will be an increase the strength of the constitution sink under of flesh, and a more robust athletic and it? Is not the whole system, which is vigorous constitution. It may be asked, nourished and supported by the blood, would you bleed in congestion of the thus deprived of the requisite material for brain, or apoplexy? Not at all! These its growth and strength ? In pleurisy there affections are produced in consequence of is a determination of blood to the pleura, the blood becoming thick, viscid or gluti- a congestion of blood in that mem- nous; which consequently impedes its cir- 24 Bleeding. culation and does not return from the Dr. Maywood, in his remarks on blood- head by the veins as fast as it is thrown letting, says, " The doctrine of blood- through the arteries by the heart; hence letting, so much insisted on by medical the accumulation or congestion. men, is fraught with most serious conse- Can no course be adopted other than quences to mankind ; and therefore, the to separate, mutilate and destroy the conscientious physician is, in duty bound beautiful and unique arrangement of to examine its merits accurately." those delicate vessels that serve as con- A medical writer observes of Dr. Rush, duits in conducting the purple stream of the great advocate of venesection «'A ve- life, through a thousand winding lanes ry worthy physician of our acquaintance, and avenues of the human body for its a few years since, put out a pamphlet to sustenance and growth: Are the stick- establish the value of bleeding in fevers; lers for the antiphlogistic treatment justi- and the only rule we could gather from it, liable, with all their wisdom of science, was to bleed ; if the bleeding did nogood, in disarranging that which they are inca- bleed again that it might do good ;if it pable of re-arranging ! Has nature in her did good, bleed again that it might do wisdom so over-stepped the bounds of more good. At length he fell sick him- perfection in not placing in every arm a self, (for physicians, as well as others, faucet that we might draw off at our lei- alas! are mortal,) not with fever,"but sure the " surplus" amount of blood ? with some chronic affection. He bled or has man, speculative man, been invest- himself, and he bled again and again, ed with the right to manufacture an in- (for no one else could be found to bleed strument by which it could be accom- him sufficiently,) and he died at last, Ia- plished ? menting that if he only could have bled The fatal effects of blood-letting are himself once more he should have recov- strongly pourtrayed by judicious writers, ered ; but in his last attempt, a mist came The late learned and experienced Dr. J. F. over his eyes, and his hand could not Lobstein, of the medical faculty of Paris, command his lancet; and he must die for late physician of the Military Hospital the want of bleeding !" and Army of France, and member of An eminent English surgeon, states, nearly all the medical societies in the civ- that, " Though the ill effects of the loss ilized world, as also of several literary of blood, unless excessive, are seldom and benevolent associations, makes the perceivable in youth, yet they rarely fail following remarks : of being felt before the age of forty-five. " Were bleeding and mercury totally People who have been often bled when prohibited, a great many physicians young, about this period of life begin to would find themselves in the inextricable be afflicted with chronic pains. They re- mazes of a sad dilemma; their time easily cover very slowly from fits of illness, disposed of. It is astonishing to find that and are very liable to febrile paroxysms so many persons, and still more astonish- and a variety of other disorders." ing that so many physicians have fallen Dr. Macintosh remarks that, " No into this extravagance. Blood, the most physician, however wise and experienced, precious matter for life, is lavishly squan- can tell what quantity of blood ought to dered where there is no necessity ; yes, betaken in any given time." often without knowledge, for what pur- Dr. Thatcher, in his Practice of Medi- porse. My remarks shall therefore con- cine, page 208, observes, that, " We vince my fellow citizens, that so far from have no infallible index to direct us."— blood-letting being beneficial, it is produc- " a precipitate decision is fraught with five of the most serious and fatal effects, danger, and a mistake may be certain Should I contribute by these remarks, to death." save more lives in future, and avert this Dr. Reed says. " If the employment of cruel practice, I would feel that gratifica- the lancet was abolished altogether, it tion which arises from a consciousness of would perhaps, save annually a greater having performed a good aft. How much number of lives, than in one year, the it is to be regretted that such an awful sword has ever destroyed." scourge of humanity should exist." To which we may add, in the language Issues aud Setons—Blisters. 25 of Dr. Henry. " Abominable is the mur- dering quack, who forever impatient to unsheath his blood-thirsty lancet, draws from a fever patient the irreparable bal- sam of life." Bleeding produces convulsions, palsy, impotence, epilepsy, apoplexy, hysteric fits, consumption and dropsy ; and those individuals who have been in the habit of getting bled, especially females, are certain to lead a wretched existence : be- ing attacked with weakness, nervousness, &c. Gen. Washington was killed by blood-letting, mercury and antimony. Eighty or ninety ounces of blood were taken from him in the course of twelve hours, besides two " moderate" doses of calomel, accompanied with an injection ; then five grains of calomel, and five or six grains of tartar emetic, &c. and in this manner was the beloved Father of his country tortured to death. Lord Byron called bleeding the «' destruct.ve art of healing"---it proved so in his case. ISSUES AND SETONS.—This prac- tice has been instituted in order to divert the diseased fluid from an affected part to an artificial channel; thereby to relieve the system from the oppression and diffi- culty under which it labored. The practice is quite common, especially in af- fection of the lungs. Yet it is impossible to suppose, that any permanent benefit can arise where the morbid matter produ: cingthis result is continually generating and acquiring strength. It mayin some in- stances, prolong the life of the patient for a short time ; but even that is doubtful, as the facilities granted for the disen- gagement of this morbid matter might produce an increased tendency in the sys- tem to its generation. Their action is al- ways unpleasant and disagreeable, and frequently produces considerable debility. In fact it is but another drain through which life must continue to ebb. BLISTERS—The precise time, and by whom, blisters were first introduced into practice, we are not able to deter- mine Previous to the discovery of the vescicating power of Spanish flies, vari- ous powerful stimulants or escharotics were employed for that purpose. Since the introduction of this article they have been, and are yet very extensively em- ployed, and their use is strongly recom- mended in almost every derangement of the abdominal organs, as well as inflam- mation of the lungs and pleura. Like- wise, in fevers and a vast variety of other complaints. Yet there are numerous in- stances of the evils produced by them.— On some constitutions a poisonous im- pression is made, attended with quickened pulse, dryness of the mouth and fauces, heat of the skin, nervousness and stran- guary, and even convulsions; and some physicians have been so much alarmed, by the occasional occurrence of these symptoms, as to induce them to apply the remedy with great hesitation. That these affections result from the absorption of the active and irritative principles of can- tharides into the circulation, there can be no question. But the above admitted evils, are not to be compared with the mischievous consequences, too frequently resulting from their use. The human system is at all times more or less impreg- nated with that morbid matter, which is constantly carried through the system by the circulation, which is capable of en- gendering disease : therefore, by placing a blister over any organ; that organ be- comes weakened or so far debilitated as to render it incapable to resist the influ- ence of this motbid matter. Such organ is thereby in a condition not to resist, but to become the convenient receptacle for whatever train of mortiid humor may be forming in the system. How frequently is it the case, where an individual has had a blister placed over the region of the Liver; that, upon the occurrence of any slight change of the atmosphere, or, hav- ing taken a slight cold, the first sensation of° pain will be experienced in that part. In Pulmonary-Consumption, what agent can be more conducive to the permanent establishment of that disease, than a blis- ter over the thorax ? How long ere an affection of the Lungs would accrue, in that individual most free from it, by placing a blister over the chest. Like bleeding, urgent symptoms may some- times be relieved by it; yet it predisposes to permanent injury, by the determination which it creates of the fluids to the blis- tered part. A little reflection will con- vince us of their utter uselessness in Con- 26 Steaming. sumption, when we consider the little in- fluence they can possibly have directly up- on (heltings. Thelungshangin the chest, they have no connection with it, and are only attached to the chest by the pulmona- ry vessels; and to the neck by the wind- pipe. Of the evils of blistering, the cases are numerous. Of all the afflictions to which mankind are liable, none are so ap- palling to the humane and sensitive physi- cian as that produced by burns. Few out of the pale of the profession are aware how frequently burns, apparently trivial and insignificant, are followed by fatal re- sults, preceded in some cases by symptoms of a decidedly typhoid character, in others disturbance of the mental functions amounting even to madness, and again not unfrequentlyare the symptoms so fal- lacious as to deceive any but the most ex- perienced in prognosis, in regard to the fatal event. Now, if there be so much danger from the inflammation of the ca- pillary nerves, by fire; how can the same effect be free from danger, whenjsroduced by blisters? Does not pathology daily prove to us that the cutaneous system is more acutely sensitive than any other or- gan. To lollow nature, to produce a natural determination k) the surface of the body is consistent and proper, such is the course nature pursues in afcstate of health. But who will asseit, that an ul- cerated and suppurative surface is a healthy action ? Will the advo- cates of blistering contend that nature frequently produces ulceis on the suiface of the body, and so relieves internal affec- tions ? We ask, if the various out- lets of the body are not destined to carry off excretions of the body peculiar to their offices, why has nature ordained more than one emunctory? Would they de- fend the doctrine by asserting, that so long as it be evacuated, it matters not by what emunctory it be done ? Is nature's course always beneficial ? This is, when unperverted by unfavorable circum- stances, true; but when peiverted, does it not pursue a course leading to death ? They would be unwilling to deny this, as it leaves the treatment pursued entirely and only chargeable with the fatal result. So numerous and so well founded are the objections against blisters, that it is a matter of wonder that they have not been long since exploded. That the action of cantharides produces inflammation of the bladder by symptoms of stranguary, is universally conceded. Is there any proof of its morbid influence being confined to the bladder? How does it produce these deleterious effects I Is it not by absorption ? Why may they not by these means be carried to any other organ ? The deleterious effects complained of, are such as reasoning a priori, might be expected from such a medicine passing quickly through the system. But when carried to other parts, the effect? would be more gradually developed, so as to ob- scure the fact. We can see no fair rea- son for doubting the liability of its pro- ducing ulceration in any other organ; especially if that organ be susceptible from previous irritation, to greater excita- bility. STEAMING, as practiced by some, at least, experience has shown, is not with- out its evils; and these sometimes have proved to be of the most serious charac- ter, even in the destruction of life. It may be said that where such was the case, the operation was performed by those unacquainted with the process.— We admit them to have been unacquaint- ed with the result, or the effects likely to be produced : had they been so, no*ex- cuse could be satisfactory thus to jeopar- dize life—a patient can be almost as easily steamed or sweated to death, as bled to death—the process and result is not vastly different. Steaming to a mode- rate extent, in many cases of acute dis- ease, is doubtless very beneficial, particu- larly vapour baths; but the repeated in- ordinate extent to which it is often carried, from the very nature of the case.must pro- duce serious mischief; and even more permanent than that of blood-letting — When bleeding is had recouise to, the thick or glutinous portion ol the blood is discharged from the orifice, as well as the more fluid parts; but in steaming, the mo6t fluid parts of the blood are disen- gaged, whilst the thick, viscid or glutin- ous principle is left behind, or retained in the system; this effect becomes very soon obvious, by an almost entire pros- Emetics. 27 tration of the nervous energy. The nerves, like all the other solids of the body, derive their support from the blood, and when the blood becomes thick and viscid, it cannot impart, or rather the nerves themselves, cannot receive that supply necessary for their support and nouri.shment. The idea likewise of steam- ing in every affection, appears utterly fal- lacious ; some complaints can only be ag- gravated and promoted by it; and particu- larly where there is great debility or prostration of strength, which so fre- quently characterize affections of the lungs, or other chronic disorde s. It would appear that there have been in- stances where patients have expired under the operation ; and although it is alleged that it occurred through misman- agement or ignorance, and that regular practitioners are subjected to the same mishaps by their mode of treatment, it neither justifies the one nor excuses the other. He who practices medicine, ought at least to know how much his patient can withstand, panicularly when it is in his power, every moment of the opera- tion, to increase or decrease its action ; the truth is, the who'.e practice is ob- jectionable, and cannot be tolerated by the scientific practical physician. EMETICS are deemed a valuable class of medicines, by both mineral and Botanic Physicians. The treatment has long been sanctioned by much high au- thority, and any attempt on my part to disparage their use, will doubtless be met with strong argument in support of their utility. As useful as they may appear to be, defended by argument ever so strong, 1 am satisfied, and much experience will afford ample testimony, of serious evils resulting from their use; especially where employed to the almost unlimited extent so frequently practised by its particular votaries. I cannot consider that na- ture ever designed the contents of the stomach should be discharged by the mouth; yet it is said does not nature in- dicate this, when she is about to disgorge the stomach of its contents ? The contents of the stomach being offensive to her, does she not repel it ? Is this action of the stomach not sufficient to deter- mine us in our prognosis? If the peristaltic motion governed the stomach, as well as the bowels, it would be ; but the case is vast:_> different, one is the reg- ular action conducive to health ; the oth- er, the irregular action indicative of dis- ease. One is the healthy action of the in- testines—the other, the irritability of the stomach, dependant upon disease. But we are again asked shall we not give an emetic to disengage the offending matter from the stomach ? What ?—increase the irriiability ? Would it not be better to al- lay it ? But, it is again said—the emetic acts by relaxation ! Relax the stomach — deprive it of its energy—subdue its abil- ity, to compel it to evacuate its contents! This is incomprehensible—but were this even probable, and were I to admit it to be so, by such relaxation, might not per- manent injury accrue to the stomach ? The safest step is to avoid the danger al- together. I think every judicious practitiouer will agree with me in this particular. The proper and only course of the alimentary canal is downward. It is the course clear- ly pointed out in the anatomy of all ani- mated beings. To institute emetics is to reverse nature's known and obvious laws. Who that will reflect for one moment, but must peiceive the injurious action of emetics, particularly in bilious affections, where they are so frequently prescribed. A physician is called to a patient, labor- ing under a bilious affection, which is in- variably produced from a disease of the liver: he at once prescribes an emetic, and the patient throws up a quantity of bile. " See what a quantity of bile he has thrown up," says the physician—" It is well that I gave him the emetic," Is it known that the stomach cannot tolerate bile, but immediately ejects it the instant it is induced into it ? Is the physician not aware that the very emetic urged the bile, (of which he speaks,) into the stomach ? If this is the effect, and that it is so, is in- disputable ; 1iow improper is an emetic— especially their frequent repetition as in bilious affections. I do not mean to be understood, that emetics are invariably useless, there may be cases where they may prove beneficial; it is their too fre- quent use that I object to. 28 Cathartics Stimulating. An emetic would be useful, where it were tender to the touch, and watery flocculent necessary to evacuate immediately the stools; in such, cases, nothing can be contents of the stomach, as in cases of more injurious than the administration of swallowing some powerful eschorotic, cathartics. Since which several mdivid- or narcotic—especially where we have uals it appears have seized upon his ideas not the neutralizing agents at hand, yet and appropriated them to their own use, their use is seldom required. The use of not only in the treatment of fever, but in emetics has led many physicians into er- eveiy case of disease, and so industrious ror. They generally have a sudorific have they been in advocating their theory effect, in consequence of the excitement of draining the system, purging the body, produced by their operation ; and the ben- purifying the blood &c. that those not efits arising therefrom, are attributed to sufficiently conversant with the manner in the evacuation of the stomach. Where which medicines to produce beneficial ef- emetics are employed, we are decidedly fects ought to operate, have been led in opposed to tartarized antimony, as this some instances into very serious errors, article, it is well known, is capable, in even in some cases we fear, to the de- the form of ointment, ol producing pus- struction of human life. Cathartics act tules upon the skin, when externally ap- by irritation, and lubrication, such as act plied. It cannot, therefore, be difficult for by irritation, produce a thin and watery us to imagine, what must be their action discharge from the bowels. The irrita- upon the tender coats of the stomach. If tion which they produce upon the mucus used at all, vegetable emetics, are far the membrane, the skin or coat which lines least objectionable. the intestines, produce a secretion or de- termination of the fluids to the bowels, CATHARTICS (Stimulating,) when and this accumulation of fluids in the judiciously administered, with regard to bowels is followed by their disengage- the promotion of the secretions, are a val- ment, and may be regarded as artificial uable class of remedies provided the arti- diarrhoea. Hence must, be seen at one cles, of which they are composed are not glance by the attentive observer, that the too acrid, or irritative a quality. Cathar- frequent use of cathartics, as advocated tics may be combined with valuable al- by some, are not so beneficial, (to say the teratives, and should the cathartic proper- least of them) as they would appear to ties be slow in their action, the alterative induce the public to believe. The Con- or purifying properties, will become as- stant use of them frequently induces Btmilated with the blood, and hence very much debility, and impairs the regular important and beneficial results may arise, action of the intestines. It is astonishing in very many cases of disease. If cathar- that this fact is not more reflected upon, tics are very active and quick in their op- when the patient is desired to commence eration, they pass off, producing no oth- with four pills as a cathartic, and to take er beneficial results, than that of evacua- them every day, daily increasing their ting the contents of the alimentary canal; number, until fifty may be taken per day, in some instances, this becomes necessa- with no more sensible effect upon the ry, particularly when there appears con- bowels than in the commencement. Who siderable constipation of the bowels. A does not perceive that the action of the doctrine was some time since advanced by bowels is thus paralized ? Besides, what Dr. Hamilton, advocating in the strongest is the benefit to be derived from such a terms the use of cathartics; he applied course? Why it purifies the blood! say them in cases of fevers, which is certain- its advocates. How ? Do the pills enter ly in most cases very judicious treatment; the blood vessels? No! That won't do. yet, in those cases where there exists in- Hew then ? W hy by draining the sys- flammation of the intestines, characteriz- tern from morbid matter. Why not ef- ed by the tongue being red at the tip and feet it then by sweating, bleeding, puking the edges, and brown in the middle ; the &c. Oh ! say they, that won't do ! Why? abdomen tumid, tense, and exceedingly Wei! I can't exactly say. Physiology. 29 CHAPTER V. PHYSIOLOGY. The existence of animal and vegetable principle. The Bile is one of the most life is confined to a certain temperature, important fluids; the office of which is The temperature which supports the one, to separate that portion of the general is as necessnry to the existence of the mass of chyle or the nutritious particles of other—both are composed of solids and the digested mass necessary for the fluids. And both derive their solid por- growth and sustenance of every partof the tions from the fluids which circulate in body. The Bile having separated the nu- their vessels. All animal matter is sup- tritious part, which is termed chyle, which ported and maintained by vegetable and is of white and milky consistency, this gaseous matter absorbed from Ine atmos- chyle is taken up by a set of extremely pherc—animated beings cannot exist in- small absorbent vessels, called lacteals.— dependent of vegetation. Nature in her These have their origin in the inner coat wisdom has constituted us with a sto- of the intestines, and passing thence dis- mach ; it is the first great enlargement of charge themselves into a tube termed the the alimentary canal. In appearance, it Thoracic Duct, which terminates near the bears considerable resemblance to a retort, neck, at the junction of the left subclavian The food on its arrival here is acted upon and jugular veins. It here unites with by the gastric juice, (secreted from the the venous blood, or dark blood, and is lining membrane or the stomach,) sep- carried to the right auricle or muscular arating it into minute particles. The bag of the heart. The heart propels it principal constituent of gastric juice to the lungs. being muriatic acid, it is not difficult to The Heart is a powerful muscular or- account for the dissolution of the food, gan, having four apartments or cavities; The experiment is easily made by placing its right and left auricle or muscular bag, a piece of meat in muriatic acid for and right and left ventricle or cavity. It 24 hours, keeping it at the natural tem- is considered the centre of circulation.— perature of the body. After this change Of its muscular power we may have is produced it is carried to the duodenum, some conception when we consider that or commencemeut of the small intestines, in man, the whole quantity of blood is through the pylorus or pit of the stomach, estimated at about 28 pounds ; and that in which it meets with another fluid at every pulsation (which if regular is called the pancreatic juice, produced by about 70 per minute) an ounce of blood an organ situated behind the stomach ; passes through it. Upon this calculation, surrounded by the curve of the duode- the whole blood in the body must pass num, termed the Pancreas; it is about through the heart every six or eight min- six inches in length, and one and a half utes This assertion is, however, made in breadth. This fluid is alkaline, with on mere conjecture; it is certain that the a small proportion of acid. By this pro- blood passes through the heart not less cess the office of digestion is completed, than 100 times in 24 hours, making due It is now presented with another liquid ; allowance for that portion which may most important; which is likewise intio- have been expended or generated Ihe duced into the duodenum from the liver, instant this venous blood, which is al- by a small duct or tube, extending from ways of a dark color, owing to its being an oblong membraneous bag, situated un- charged with carbon resembling char. der the liver, to which it is attached in coal, generated from the decomposition the right side termed the Gall Bladder, of animal and vegetable matter in the which is the reservoir of this fluid when system. The veins being absorbents, secreted by the liver. The constituents take up a large quantity of the decora- of bile are principally alkali and a bitter posed matter, consequently their dark 30 Physiology. color. As soon as this blood is present- ed in the lungs its dark property is lost; it becomes of a lively red owing to the neutralization of the carbon. The cause of this is plainly understood ; at every exhalation, carbonic acid gas is thrown off, while at every inhalation, oxygen and electricity are absorbed. An affinity ex- isting by the power of electricity between the oxygen and carbon, carbonic acid gas is produced and expelled. Oxygen and electricity are the vivifying principles of life; while carbonic acid gas is destructive to life. If, in illustra- tion, a person be sleeping in a tight room where there is burning charcoal, the mo- tions of life soon cease. The reason is plain ; the oxygen contained in the room becomes overpowered by the carbonic, acid gas produced by the consumption of the charcoal. But if before the functions of life cease to perform their offices, wa- ter be thrown upon him, he recovers— water being principly composed of oxygen. The blood now sent to the lungs, having become decarbonized or divested of the inert part, is fitted for the purpose of sustaining and promoting every part ol the body. After being thus manufac- tured in the laboratory of man in the mannerstated.it is returned to the heart by the pulmonary veins; thence it is forced through the arteries, the " aorta or parent tube subdivided into thousands of tor- tuous shoots, on the sides of which my- riads of vessels like the down of a peach conduct a circulation: a tissue of arte- ries ; they extend to every part, becoming to diminutive that the naked eye in vain endeavors to detect them" In this cur- rent is embraced every constituent neces- sary ; the nerves attract by the power of tiectricity the materials requisite for the nervous fluid. Every bone, muscle, liga- ment, &c, are made and supported from it. Unerring, they convey just the sort of material necessary to mend a bone, heal a cut, lubricate a joint and to supply the waste that is continually taking place in the system. We cannot refrain from alluding to one of these branches, of arteries, per- taining to the organ called the spleen, which pursues a serpentine course over the pancreas, behind the stomach, in which it gives off branches to neighboring parts, then enters the concave surface of the spleen, where it ramifies into innu- merable smaller arteries, from which the blood is taken up by minute veins, which uniting with each other form the splenic vein. We shall now proceed to illustrate in as concise a manner as possible, the situ- ation and uses of the other organs, not previously named in the course of the di- gestive processes and circulation. The Spleen, (usually called the milt in animals,) is situated on the left side between the eleventh and twelfth false ribs; it is of an oval figure, and is con- nected with the stomach, the omentum or cawl, the left kidney, the pancreas and the colon or large intestine by seve- ral Jigamentsand vessels. In anatomical structure the Spleen resembles the brain more nearly than any other organ of the body; being located in the upper left side ol the abdominal cavity, some have con- ceived its use to be to balance the liver on the right side ; perhaps, ori the prin- ciple of the Dutchmfjii in days of yore, who placed a bushel of wheat in one end of a bag, and an equal weight of stones in the other to balance the bag while " going to mill." The substance of the Spleen, though firmer than that of the brain is yet softer and more pliable than any organ ex- cept the brain. The capillaries of the skin transmit colored blood. Ali the nerves going into the Spleen grow larger, softer, pulpy, and at length mingle apparently in its substance like those of the brain.— Those animals devoid of a brain, are also destitute of a Spleen. Both the brain and Spleen are glandular, yet neither has any excretory duct: both are more largely supplied by blood than any other organ, the blood in the splenic vein has nearly or quite lost its coagulating property.— These facts sufficiently establish the an- alogy of function between the brain and Spleen. The assertions made by some medical authors, that the Spleen has been removed in animals and man with little or no injury, I shall take the liberty of denying. Anatomy does not discover any blood vessel communicating between the Spleen and stomach or portal vessels; Physiology* 31 hence the idea that its function is auxili- ary to digestion cannot be sustained. Its office is to separate from the arterial blood those elements, or principles, as, oxygen, electricity, perhaps phosphoric acid, which constitute the influence, fluid or power of the nerves of involuntary motion, or primitive system of nerves, These nerves are the instruments of se- cretion, assimilation, excretion, circula- tion, absorption, digestion and respiration in part. This system of nerves is formed long ere the brain or spinal mar- row. The Spleen does not, however, furnish aH the elements for the supply of this class of nerves. They are every where to be found intimately connected with arteries, following them in their course and convolutions, often pene- trating their coats and expanding upon their inner surface; thus much of their support is derived directly from the blood, which fully explains the phenomena that animals have lived and maintained a feeble existence for a while after the Spleen has been extirpated. These nerves are no where to be found in com- munication with the veins They are the origin or primary structures of all animals, and the class of animals below fishes have this nervous structure with- out either brain or Spleen. The BRAIN is a large round organ, situated in the cranium or skull, sur- rounded by a thick and somewhat opaque or dark and insensible membrane, the dura-mater formed by two layers, which defends the Brain and adheres strongly to the internal surface of the skull. This membrane is supplied with blood from the internal masciUary artery, or artery of the jaw, which is a branch of the exter- nal carotid artery—named so on account when tied or its circulation being ob- structed, produces sleep - when it reaches this membrane, the dura mater, it di- vides into three or four ramifications, and spreads itself throughout this coat to the anterior, middle and posterior lobes of the Brain The Brain is thus largely supplied with arterial blood. In the Brain the nerves of sensation derive their power, and they are the second formation of nature. They are the source by which we derive all our sensations of sight, hearing, feeling, tasting, &c.— They,acting in concert with the organic nerves, deriving their power from the Spleen, are the cause of the growth and de- cay of the human boly. But how do the nerves know what peculiar property is necessary for the sustenance and growth of the bone, cartilages, &c, and by what power do they supply all the wants of the human structure? They are electric conductors; and by the power of electricity, (attraction,) they absorb and deposit every constituent necessary for that purpose. LIVER—The largest gland in the human body is that of the liver, situated in the abdomen, of a deep dark color, divided into two principal lobes, which are subdivided intosmaller ones; the right extending far down the right side, thence across the middle of the body towards the left side, which it however does not reach, as the large end of the 6tomach, as has been stated before, comes between the left lobe of the liver and the side ; it is attached firmly to the diaphragm or midriff, separating it from the chest; much the largest part of this viscus lies on the right side; the liver receives a large proportion of the venous blood from the lower extremities and ab- domen by a large vein called the vena portar or portal vein which upon entering the liver branches off in every direction, suffusing the whote substance of the or- gan. From the venous or dark blood the bile is produced. Under the liver is situated the Gall Bladder, the use of which is to receive and retain the bile, which is carried from thence as previous- ly stated. The KIDNEYS are situated on each side of the spine, a little above the bips. The right is somewhat lower than the left, and nearly in contact with the liver; the right lobe of which overlaps the Kidney. The external portion of the Kidneys are full of small blood vessels. The Kidneys are constantly largely sup- plied with blood. The artery supplying the Kidneys is a branch of the aorta. 32 The Cause and Symptoms of the most Prevalent Diseases. CHAPTER VI. THE CAUSE AND SYMPTOMS OF THE MOST PREVALENT DISEASES. Man is one of the plants of Nature's of diseased action, rendering the fluids of garden ; like them, he is nourished and a depraved character. The fluids being fed—ihat is, he partakes of the food the primitive effect of the causes of dis- which she produces—inhales her atmos- ease, the solids become secondaiily affect. phere—grows to his stature—is subjected ed in consequence of, and by the morbid like the stately pine, to all the tempestu- constituents or state of the fluids. ous winds of life, and, like all animated In our organization we are furnished beings or vegetable substances, loses his with an organic structure, which is well powers of animation, becomes disorgan- calculated to render us to a certain degree ized, dies, and returns to the elementary independent of disease, provided attention principles from which he was formed, be paid to it on our part which the im- All na'ure, animate or inanimate, is but portance of it requires. That disease of one continual routine of organization and every description results Irom the accu- disorganization, decomposition and re- mulation of morbid matter in the system, composition! Yea, one eternal change, cannot be the subject of doubt. In some If it were not so, we could not be ani- instances, years may transpire before the mate or intelligent beings. To escape effects of this morbid matter may so fully disease is impossible : we are exposed to develope itself as to be characterized by those causes by which it is generated any disease. Yet the fact is incontro- every moment of our lives; the gasses of vertible, that it was gradually and con- the atmosphere are capable of producing stantly accumulating, and at length man- it, especially when in situations where ifesting itself by an attack upon 6ome we may be exposed to the effluvia arising organ, the structure of which is not so from the decomposition of vegetable or perfect and vigorous as another ; 01 the animal substances; the water we drink system being more or less charged with may be impregnated with deleterious it. is subjected to some excitement, as a substances which it has acquired through sudden transition of temperature and ex- the different stratas of earth. If we use posure, a violent attack of fever, acute animal food of any description, we may inflammation has followed. These ac- likewise become affected, as all animals cumulations of morbid matter in the are subjected to disease. fluids, may with propriety be termed the When we take a pathological view of "seeds of disease;" which, constantly diseases, we find that they all have their accumulating, must corrode and disorder origin in a morbid condition or quality of the solid structure of the human body. the circulating fluids of the human body, This morbid matter can be no other than which may be acquired hereditarily—by the product resulting from the decompo- the inhalation of poisonous effluvia—by sition of the food taken into the stomach sudden transitions of temperature—or by to resupply the waste which is continu- the inoculation of virus, or other foreign ally taking place in the whole animal substances into the circulation. Like- economy. Food taken in the system wise a diseased state of the fluids may be having performed the offices of supplying produced by the undue, obstructed, or it with such materials requisite for its increased action of any one of the excre- support, the useless particles are diseh- tory organs; in which case, they would gaged therefrom, as unfit for any further become weakened, and thereby incapable purpose in the animal machine. This of performing their offices; or, in other unserviceable matter must, necessarily, words, discharging from the system such he of a putrescent character, which is morbid accumulations as are formed by constantly increasing, and which, if not constant decomposition, and which would neutralized (rendered harmless) and ex- by retention in the system, be the cause pelied from the system, must produce The Cause and Symptoms of the most Prevalent Diseases. 33 disease. To what extent this putres- cency must accumulate to produce death, is impossible to say; but it is certain that it must be to such a degree as to render an organ essential to the support of life incapable of performing its functions. The principal excretory organs by which the constant decomposed matter is carrieij from the system are the skin, intestines, the kidneys and the lungs in decarboni- zation; hence the importance of their duly performing their offices. There are other exhalents, as the eyes, ears, nostrils, &c., but the healthy action of the first is by far the most important. The veins, as stated under Physiology, are " absorbing vessels ;" hence they readily absorb or take up this effete matter charging the exhaling organs, which should have been thrown from the system ; this matter, charging the blood, tends to accumulate rather than diminish. From the venous blood the bile is pro- duced. There is no organ of the body so sus- ceptible of disease as that of the Liver; and that in its healthy action depends in a great measure the health of our whole organization, is true. The office of the Liver being to secrete or elaborate the bile; the duty of which fluid is, to sepa- rate that part of the food calculated for nutrition, termed chyle, from the general mass. If the functions of the Liver become obstructed or weakened, serious mischief must ensue. The alimentary matter, though perfectly digested in the stomach, and then passed into the first intestine (duodenum) is not there duly separated into two distinct portions— chyle and chyme—or, in other words, the chyle or nutritive portion is not suf- ficiently separated from the general mass for the lacteal absorbents to take up and supply the natural wants, required by the continual waste of the system. Many persons are laboring under a derangement of the Liver for years, who have not the least conception of its exist- ence. Any transient symptoms of indis- position which they may experience is attributed to a different or mistaken cause, and are thus incapable of guarding against this insidious enemy of their repose. A disease of the Liver itself is some- times characterized by pain in the right side, extending more or less into the shoulder, between the shoulder, or under the shoulder blade. It sometimes be- comes torpid and inactive; appears to enlarge or swell, pressing against the dia- phragm, which separates the chest from the abdomen, thereby lessening the ca- pacity of the thorax, or cavity of the chest, giving rise to shortness of breath, difficulty of breathing, phthisic, asthma, &c. A diseased state of the Liver, in connection with an impurity of blood, necessarily produces an unhealthy state of the bile, which may become thick, insufficient, thin, superabundant or acrid. Where the bile is thick or viscid, it arises from the inactivity of the Liver, and be- comes hard and impacted in the gall duct, and even in the Liver and gall sac, pro- ducing what are termed gall stones, and hard hiliary concretions, the passage of which through the gall duct, gives much pain and distress. This thick state of the bile, in most instances, is equivalent to a deficiency; and the consequence is a sour state of the stomach or bowels. The bile is an alkaline substance, showing conclusively its formation by the decom- position of animal matter; and when sufficiently alkaline, and flowing into the duodenum in sufficient quantities, neu- tralizes the acidity which may be there generated. The thin, superabundant, and acrid state of the bile, may be considered under one head, for they are frequently attend- ant on each other. When superabundant, it is usually thin ; yet some time may elapse before it becomes acrid ; according to the state of the Liver. If superabund- ant, the individual will frequently com- plain of sickness at the stomach or nau- sea, have a capricious appetite for food, and not 'infrequently throw it up. It may be known by its extreme bitter taste. Under such circumstances the bowels are generally very costive. Whenever the alkaline properties of the bile are overcome by acidity, diarrhoea follows, as witnessed by the free use of vinegar and water, or the eating of sour or unripe fruits, so frequently practiced by children in the summer season. When the bile becomes acrid, it irritates and in- 34 The Cause and Symptoms oj flames the mucous membrane of the small intestines, and in some instances produces ulcerations of the pylorus, or commencement of the intestines. They complain of a burning, painful, sinking sensation, or great weakness just below the pit of the stomach; are subject to con- siderable flatulence, and sour, burning eructations, or belching and indigestion; so much so as to often be compelled to abstain from animal food. At this day it is considered a complaint of the stomach, and is fashionably termed Dyspepsia. This thin and acrid state of the bile pro- duces other derangements, by being ab- sorbed into the blood-veseels. The evi- dence of which is clearly manifest in the skin, the eyes, and countenance, subject- ing the individual to attacks of bil- ious fevers, &c.; even the yellow fever is produced by this cause. The absorption of this bile into the blood, renders that fluid thick and viscid, in consequence of which, much greater labor of the heart is required to propel it through the arteries to the surface of the body; which labor weakens the heart, and palpitations follow, and even a dis- ease of that organ itself often ensues. From the debility of the heart thus in- duced, it is unable to throw the blood to the extremities, hence the patient is sub- jected to cold feet and hands, and at the same time with vertigo, dizziness, pain in the head, ringing in the ears,&c. The arteries leading to the head are large, and owing to its proximity there is but little difficulty in throwing the blood to the head by the heart; that blood has to re- turn through the veins; but as there is no heart to propel the blood from the head through the veins, the motion is slow, and itc thick or viscid character renders it still more sluggish ; hence, ac- cumulations of blood take place in the head—press upon the brain—producing the difficulties above stated; even apo- plexy is caused in this way. At times obstructions for a moment arise, which are termed " a rush of blood to the head." Numbness of the limbs, shooting pains through the breast and other parts of the body, nightmare—even palsy and par- alysis are produced by this state of the blood. In consequence of this morbid the most Prevalent Diseases. accumulation of bile in the blood, charg- ing the capillaries, small and hair-like blood-vessels, which are immensely nu- merous, the pores of the skin become obstructed, charged, and filled with an oily, hard, saline substance, so there is but little perspiration; thus the disease is thrown more forcibly upon the internal organs, especially the kidneys ; and at the same time if the concave surface of the Liver be affected, a disease of the kidneys is almost invariably produced; evinced by pain and weakness across the small of the back, and-extending down the limbs, with many other very distress- ing symptoms. Dropsy is produced in this way. Nervousness, debility, and weakness, to a greater or less extent, are the attend- ants of a diseased Liver. The thickened glutinous and viscid state of the blood, renders it difficult for the nerves, liga- ments, cartilages, &c, to^ absorb from the blood that fluid necessary for their sup- port; and, like a spear of grass in a drought, these organs are io_.a measure deprived of their energy and support. Some individuals suffer excessively from nervousness. When this viscidity is so great as to produce obstrucjtrpns or depri- vation in a part of the power^of action, the nerves of sensation baeo'me affected, producing insanity. This*acrimonious bile so charging the blood and acting upon the muscular flesh, produces humours, eruptions," canker," &c, even scrofula frequently originates from its acrimony extending to the glands. When the up- per or convex surface of the Liver be- comes diseased, it extends its influence to the lungs, from which it is only sepa- rated by a thin membrane called the dia- phragm, which the lungs in the chest, and liver in the abdomen, are nearly in contact. Cases have occurred where the Liver and Diaphragm have ulcerated to- gether, and portions of the Liver and Lungs have been expectorated through the cavity of the Lungs. Having traced the disease of the Liver through its various mutations, and shown a portion of the symptoms arising there- from, yet the illustratior.s might be greatly extended. It is very doubtful whether any disease of a chronic character Pulmonary Consumption. 35 exists, in which the Liver does not per- form a prominent part, or is not more or less concerned; and I venture to affirm that health can in no instance be main- tained where the transactions of the Liver are in any way imperfect. The freat prevalence of Consumption of the ,ungs in this climate, generally speak- ing, originate from a morbid derangement of the functions of the Liver—particular- ly that form of disease which physicians have called " Dyspeptic Pthisis." I do not wish to be understood as saying that all diseases of the lungs ori- ginate from a previous disease of the Liver. Other causes may exist favora- ble to such a result, as hereditary dispo- sition, narrow chest, imperfect structure and the result of acute diseases, as fevers, pleurisy, inflammation of the lungs, in- juries of the breast, &c. PULMONARY CONSUMPTION. Pulmonary Consumption has long been considered as a most fatal malady; thousands yearly sink under its devasta- ting power; all ages and sexes become its victims. It is a Hydra which has destroyed its millions, and has baffled the skill of thousands. In fact, so firm are the convictions of its incurability, that an individual, in most cases, is consigned to death the instant the disease becomes manifest. The belief of its incurability could only have arisen from the little suc- cess which has attended the course of treatment hitherto pursued, respecting it. Its principles, its action its nature, have never been developed. It is an error of the most serious consequence, that prac- titioners of medicine direct their efforts to allay symptoms, instead of a scrupulous inquiry into the original or proximate cause : applications to relieve present or urgent symptoms, may have the most un- happy effect, by aggravating the primary cause, as is evident by the administration of expectorants. The whole course pur- sued by physicians, for this disease for *the last century, with but little exception, is wrong : one more calculated to aggra- vate and increase the disease, than to allay it; and I have little doubt, that in many instances, the disease by such treatment, has been permanently established in many individuals, who, had it been otherwise, might yet have enjoyed a rea- sonable degree of health. Of the cura- bility of Pulmonary Consumption, if properly understood, there can be no reasonable doubt; but it is the want of a true understanding of the disease which has rendered it so fatal. Dr. Carswell, a celebrated European writer, observes—" Pathological anato- my has, perhaps, never afforded more conclusive evidence in proof of the cura- bility of a disease, than it has in that of Tuberculous Phthisis." Dr. Clark, of London, says—"That Pulmonary Consumption admits of a cure, is no longer a matter of doubt; it has been clearly demonstrated by the re- searches of Lsennec, and other modem Pathologists." In the Military Hospital at Capua, where the greatest number of Consump- tive patients of the army are sent, the most recent and extensive experiments were made by Dr. Giovanni de Vitis, chief Physician to the Military Hospitals of the Neapolitan Army; and from the 1st of May 1828, to the 8th of January 1832, there were sent out of the Hospital per- fectly cured; Forty cases of Chronic Ca- tarrh, Forty-seven of Consumption in the first stage, One Hundred and Two in the second, and twenty-seven in the third, making a total of Two Hundred and Six- teen cases; One Hundred and Seventy- six of which were cases of Consumption. Dr. Beddoes reports to have cured three cases out of five.of Tubercular Consump- tion, in his practice. Dr. Magennis, of the Royal Naval Hos- pital at Plymouth, in England, reports that of seventy-two cases of Consump- 36 Pulmonary Consumption. tion, 25 with ulcerated lungs recovered, and fifteen from the stage previous to ul- ceration. Thirteen, in an early stage of ulceration, were discharged greatly reliev- ed, nine in the previous stage ; and but ten cases entirely lost. The above statements are such that no one can deny, or that no intelligent medi- cal man would dare to deny. The direct action of the disease upon the lungs, in ordinary cases, is first produced by debili- ty. The blood, as previously shown is thrown from the heart to the lungs at every pulsation, and is again returned from the lungs to the heart; yet if the lungs in their original structure are weak, or have subsequently become so from any cause, they are unable to return the blood from them to the heart, as fast as the heart throws it to them ; this results in accu- mulations of blood in the lungs — Their arteries, veins, and capillary ves- sels become filled, charged, and gorged with blood; the consequence of which is swelling or enlargement of the lungs, partially filling the cavity of the thorax, that there is not sufficient room for their expansion, and a full inhalation is almost impossible ; hence the shortness of breath or difficulty of breathing:—When the lungs are thus charged and distended with blood, upon some slight exertion, as coughing, or any violent action, some of their small blood vessels become ruptured, and blood is discharged at the mouth, called, " bleeding at the lungs." This ac- cumulation of blood in the lungs, is the cause of irritation, which produces ulcers or tubercles upon them, as well as the deposition of tuberculous matter from the blood in the air cells of the lungs Having given a synoptical view of the most prominent chronic diseases, with the symptoms by which they may be distin- guished ; and also shown by what means morbid matter is introduced into the sys- tem; our next enquiry should be what action it is capable of producing. Dis- eases are considered as acute and ehronic. Acute is a term made use of to signify a disease of short duration, and generally of a somewhat violent character.— Chronic is used in opposition to acute, to signify diseases of a long and protracted character. My views are somewhat dif- ferent, I consider the term ambiguous, and not calculated to convey the true na- ture of the case. The body is composed of solids and fluids, and the disease term- ed acute disease, I contend is confined to the fluids; the idea maybe much more easily comprehended by considering an acute disease as fever, an inflammatory action of the fluids; an acute disease may be general, as in fever; or local, as the liver, lunge, &c. Chronic diseases, I would consider a disease of the solids, in which there is little if any acute inflam- mation ; yet a disease of the solids must be preceded by a diseased or inflammatory action of the fluids; and so long as it exists, supported by them. The only actions that can take place, in either animal or vegetable matter, are three in number; and three only! What! but three amidst the thousands of diseases to which mankind are subjected ? are there but three actions ? but three.— there may be numerous symptoms—a variety of symptoms characterize every disease, but the direct actions are but three —These actions on vegetable mat- ter are known by- vinous fermentations, succeeded by the acetic, which is again succeeded by the putrefactive. The ac- tion on animal matter is—first, irritation, succeeded by inflammation, terminating in putrefaction or decomposition, forming matter or pus. When this morbid or de- composed matter, which should have been thrown off* by the 6kin, bowels and kidneys is retained in the system, and a sufficient quantity of it has accumulated in the system, disease is produced; the first action of which is irritation, and that irritation manifests itself upon the weakest organ, 't having the strongest predisposition, simply that from its de- bility, it is least able to resist it. If the internal organs are sufficiently strong to resist it, it is thrown to the surface, and makes its appearance upon the skin in the form of ulcers, boils, eruptions, &c. Under such circumstances, as is frequent- ly the case from some sudden excitement in the system, as the sudden disgorgement of bile from the liver, as sudden change of the atmosphere, &c, its action becomes violent, and results in fever. I would not say that all fevers are produced in Concise Synopsis of the Analytical Practice of Medizine. 37 this way; accidental causes, arising from external circumstances, as well as some cases of nervous excitement, may contri- bute much to the result; but when fever is induced, its nature and action are the same. Among all the fluids of the body, there is none of more importance than the blood. It is this fluid which produces all the other fluids of the body; and they, the solids; hence the importance of its being constantly in a healthy condition. It is not so when charged with this mor- bid matter—it is not so when too thick or too thin. The blood consists of two parts; the one the watery, serous, or thin part,—the other the thick part, or clot; when the thick part ahounds, it requires to be attenuated; and when the thin part abounds.it requires consistency. A free use of animal food charges it with hu- mours, and an entire vegetable diet ren- ders it weak and watery. CONCISE SYNOPSIS ANALYTICAL PRACTICE OF MEDICINE. 1 st. There does not exist in every ani- mated being, an indefinable principle, which superintends and controls all the secretions and excretions upon which life and health depends, called archeus, vis medicatrix natura, vital principle, effort of nature, &c, as contended for by med- ical men. 2nd. The human body is composed of fluids and solids compounded accordingto the laws of chemical affinity, from the world of inert matter surrounding us.— These laws are in action and are mani- fested by every change in matter, wheth- er animate or inanimate. Matter is gov- erned by no other laws: they are laws regulating and governing change of mat- ter and are called the laws of nature. 3rd. Animal matter cannot be formed from mineral; but on the contrary, is ex- clusively the product of vegetable ; con- sequently the only corrector of animal matter is necessarily vegetdble.—Vegeta- ble remedies. 4th. Life and Death, Health and Dis- ease are certain states in which animal and vegetable matter may exist: all of which states are governed by and depen- dent upon no other than clearly definable natural laws. 5th. Animal Matter (unlike vegetable) during life, is constantly subjected to change—composition and decomposition —constantly wasting and constantly forming. 6th. The changes which the laws of nature produce in living matter (under ordinary process) by which it is again re- solved into its original elements, are but three. In vegetable they are denomina- ted vinous, ascetic and putrefactive fer- mentation ; in animal, irritation, inflama- tion and putrefaction. When these chan- ges take place in a very slow and protrac- ted manner, the casual observer may doubt their existence, but when they pro- ceed with rapidity they become so obvi- ous that none will ask proof of the real- ity. These changes are necessarily taking place every moment of its existence and the putrescent matter formed by this de- composition, is (when in health) carried from the system by the various excretory organs as fast as generated. (It is other- wise in disease.) 7th. Disease is produced by the debili- ty or inefficient action of some one or more of the excretory organs, as the skin, bowels, kidneys, &c, by which the pu- trescent matter formed by constant decom- 38 Concise Synopsis of the Analytical Practice of Medicine. position cannot be carried from the sys- tem, but is there retained, producing thick and viscid blood : and consequently im- peding circulation, congestion stagnation, &c. The natural heat of the body being about 95 degrees, this product of decom- position soon produces inflammatory ac- tion in a weakened and debilitated organ or in that part of the system where the blood most accumulates; followed by ul- ceration, or by the irritating effects of this morbid matter being disseminated through the circulation, fevers of one character or another arise as bilious, intermittent, lung fever, &c. Disease may also be produced by the inoculation of some virus by which the blood becomes contaminated, by food of an unhealthy nature ; water and other substances, containing properties capable of counteracting the laws conducive to health or by the inhalation of gasses which may charge the atmosphere we breathe. 8th. We contend that there are two to- tally distinct nervous systems, emanating from two separate sources and performing two distinct different offices; one of which is the source by which we derive every sensation—the other, that by which the growth and decay, the secretions and ex- cretions of the entire human body is reg- ulated and governed. 9th. We recognize the periodicity of disease—that the symptoms of all disea- ses are more violent at some periods than at- others, as in ague and fever. 10th. We reject the use of all harsh and debilitating agents as Mercury, An- timony, arsenic, and all metallic oxides, either internally or externally. Bleeding, Blistering, Emetics, Steaming, Issues, Setons, drastic Cathartics, and all agents capable of producing debility—making a patient sick to make him well, or tearing down the system for the purpose oi building it up again ! or the use of any agents as stimulants by which the ner- vous system is excited to action, beyond its natural powers of strength which is invariably followed by greater prostra- tion after the effects of the stimulant is expended. The nervous power being the capital upon which the physician must depend for a restoration to health requires the strictest care and attention in its pres- ervation. If the nervous system becomes so exhausted as to render it incapable of performing the functions requisite for the sustenance of the whole human body, res- toration to health is impossible. 11. The qualifications necessary for a physfcian are, First, A knowledge of all the laws of nature by which animal mat- ter is governed—a knowledge of the chemical constituents of every fluid and solid of the human body, the office they are destined to perform in the animal economy and the changes they are capa- ble of undergoing, by which unhealthy or diseased action can take place. Sec- ondly, A knowledge of the chemical con- stituents of every agent employed in me- dicine. The knowledge is imperatively necessary to understand the modus ope- randi of medicine—to enable the physi- cian to prescribe that article capable of neutralizing, dissolving and rendering harmless any character of morbid matter generating or accruing in the system—to understand what the invisible action of medicines are which produces each par- ticular visible effect. INSTRUCTIONS By which individuals require to be governed when prescribing our medicines. The Vegetdble Rob is required where the tongue shows a whitish coat and the body of it inclined to a pale color, rather thick and broader than usual, showing the blood to be slimy or charged with mucous, it is a powerful solvent and dissolves thick and viscid obstructions throughout the entire system, as biliary calculi or gall stones, which frequently form in the Liver and bile duct—thick viscid bile, &c. It dissolves urinary calculi which form in the bladder, causing gravel—the thick mu- cous and slime with which the blood is often charged, tumors of the abdomen and other parts. It is required in all cases where the above description of tongue exists; in numbness of the limbs, palsy, heavy dead pains, called rheumatism, pain and diz- ziness of the head inclining to apoplexy, costiveness, scanty or pale urine, blood becoming watery terminating in Dropsy, cold extremities, tuberculous deposits in the Lungs, Asthma, Phthisic, &c. The Antiseptic Detergent removes inflammation by neutralizing that aerid matter in the blood, producing and supporting it. The Detergent should be used where the tongue or edges look red or inflamed—the bowels inclined to be relaxed—sore mouth or throat sometimes called canker—■eruptions upon the skin called humors of one description or another, as erysipelas, &c.—ulcers—where there is much pain in either of the sides or bowels—thin and acrid bile producing bilious diarhoea, difficulty of breathing in consequence of inflammation of the Liver—weakness at the pit of the stomach, pain across the small of the back, high colored urine sometimes voided in small quantities or attended with heat in passing it where there is much weakness or debility—palpitations of the heart, or throbbing sensations in various parts of the system. The Percuro is required when the tongue is thick and not very broad, and the body of it of a dark appearance, showing the blood to be highly charged with carbon, the pulse generally hard but not unusually quick, the bowels more or less costive, the urine somewhat thick, and depositing at times a brick like sediment, little per- spiration or at least a deficiency, the skin somewhat rough or hard, sharp pains in the limbs, chest and other parts of the body, particularly the head and face, called tic douloureux, neuralgia, fyc, at times attended with numbness, dizziness, difficulty of breathing, fullness of the chest, phthisic, asthma, #c. It frequently occurs that it is necessary to use two medicines at a time. If there exists a thick and bad state of the blood and inflammation, it is necessary to deter- mine whether it be produced by the blood being charged with carbon or mucous; the above described appearanee of the tongue will enable the individual generally to determine. If it be produced by carbon, it will be necessary to use the Percuro and Antiseptic Detergent at the same time. If the inflammation be high, the Deter- gent should be taken twice a day and the Percuro once. If the inflammation be not great, the Percuro twice and Detergent once. If the vicidity of the blood be occa- sioned by mucous, the Rob must be used either once or twice a day in conjunction with the Antiseptic, according to the state of existing inflammation. Sometimes by using either the Rob or Percuro alone, inflammation may arise in consequence of the acrimony which developes itself by dissolving the viscid matter charging the blood: in such cases, it will generally be sufficient to use the Antiseptic once a day and the other medicine twice. Where a patient is weak and nervous, and there is not too much i nflammation the Nervine Cordial should be used two or three times a day in addition to the 40 Instructions when Prescribing our Medicines. other medicines, taking It at the intervening times between using the others. The Nervine Cordial is not prepared from those articles that act as stimulants, but from such as support and increase the healthy character of the nervous fluid. It will be found of much benefit in Ague and Fever if taken only during the intermission of the paroxysms. Medicated Wrapper.—This article is directed in diseases of the Lungs, and is worn by the patient around the body next the skin. The object Of using it, is to induce the blood to circulate upon the surface of the body—to charge the capillary vessels of the skin, and theieby counteract the tendency of blood to the Lungs, which is invariably the case where the lungs have become weak, as at every pulsation of the heart the blood is thrown to the luDgs, where it undergoes the change from venous to arterial blood. By the blood accumulating in the lungs, it becomes stagnated and consequently hepatization takes place. Loading- and distending the blood ves- sels of the lungs, irritates them and produces cough, which in its turn is followed by inflammation and ulceration, and not unfrequently the rupture of some bloodves- sel of the lungs. If this blood be induced to quit the lungs, or the lungs be protec- ted from this accumulation and engorgement of blood,