CASE OF NiEYUS ; OR HYPERTROPHY, CORRUGATION AND DISCO. LOR ATI ON OF THE SKIN. [Read before the Norfolk District Medical Society, May 9th, 1866, by G. J. Arnold, M.D., of Roxbury.] Maey 8., aged 25 years, a poor, semi-demented creature, was con- fined with an illegitimate female child, at full time, after a normal labor. Upon the left arm of the child, involving nearly the whole limb, was a peculiar deformity, which had for the most part the ap- pearance of an immense mole. Beginning just above the wrist, it covered the entire arm and shoulder, spreading out upon the chest in front nearly to the nipple; upon the back to the median line, and descending as far as the angle of the scapula. Its color was an in- tense brown, or quite black, for the most part; much lighter on the fore-arm, but there also with black spots upon the brown. Most of that on the body was shaded off with a lighter brown, varying from half an inch to two or three lines in width. Upon the top of the shoulder, the upper portion of the arm, and about the region of the spine of the scapula, the surface was deeply corrugated and fissured. The flesh was raised into ridges and prominences, and was largely nodu- lated. These nodules were to the feel quite firm, as if arising from thickening and obesity of the skin and the tissues just beneath it. The region of the biceps seemed almost entirely occupied by these thickened masses, which were much blacker there than on the sur- rounding parts. An abundant growth of hair also covered this part,, quite long, silky, and perfectly white. There was another large spot upon the back and upper part of pel- vis of left side, measuring from two to two and a half inches in diame- ter, somewhat oval in form, not intensely dark, but with some promi- nence and density of tissue. Upon this spot also the hair was abun- dant. Still another spot, of about half an inch in diameter, occupied the right hip. There were also numerous scattered brown spots like common moles, measuring from two to three lines in diameter, here and there over the body and extremities; but hardly a trace upon the head. There was no appearance of ecchymosis in any part. As the child died twenty-four hours after birth, photographs were taken, from which the above wood-cuts have been prepared, which will give a better idea of the case than a more lengthened description. In Saint-Hilaire’s “ Anomalies de I’Organization,” vol. i., p. 331, we have the following, which more nearly approaches the case above reported than any other we have been able to find. We give a trans- lation. “ The lower part of the back, loins and thighs were covered with a blackish, thickened, rugous, and deeply furrowed skin—with an appearance of cicatrices in many places, and covered with short, coarse and pretty closely set hair. In these cases the skin present- ed a striking resemblance to that of a hog. Besides this large blackened surface, the limbs, the whole body, the face, and even the scalp, were thickly spattered with spots of a reddish-brown color— some round or oval, others elongated and irregularly quadrangular, and others triangular. The skin otherwise was very white.” In a note, Saint-Hilaire says, “ the color affected the whole thick- ness of the skin itself”—as it apparently did in the case we report.