A United States Army Medical Department, continuing Education program, technical problems, vascular with John D Welchel, Lieutenant Colonel US Air Force Medical Corps Chief Transplant unit, Wilford Hall US Air Force Medical Center, Lackland Air Force Base. As experience in renal transplantation has increased over the years. The instance of primary vascular complication appears to be decreasing as reflected in the transplant registry. The time honored use of the hypogastric artery and the iliac vein of the recipient to revascularize a graft still appears to be the preferred technique in the majority of transplant centers. The increasing utilization of donor graphs with multiple renal arteries, pediatric transplants and occlusive vascular disease and transplant recipients and donors have tested the ingenuity of the of the transplant surgeon and has resulted in the development of various techniques for the successful re vascularization of renal graphs. The development of preservation methods that enable the maintenance of kidneys outside of the donor has enabled the surgeon to repair damaged vessels or to modify the vascular anatomy to facilitate revascularization in the recipient. Thrombosis of the arterial and venous anastomosis are complications that have been seen in most if not all major transplant programs. First, slide. The suggested claw causes of these problems include poor suture, technique, excessive vessel linked with acute kinking, obstruction of the renal vessels by poor location or positioning of the graft. Incomplete endarectomy of the donor recipient arteries, infection and rejection, partial thrombosis of an arterial or a Venus anastomosis may be relatively asymptomatic or it may be associated with deterioration of renal function. Complete obstruction of the renal artery results in sudden oligo and rapid death of the graft. If a graph fails to produce or ceases to produce urine following transplant, the possibility of a vascular inclusion must be different. Differentiated from acute tub of necrosis, renal obstruction or hyper acute rejection. We have found that the use of magnesium scans to quickly rule out the arterial collusion in such situations can frequently help you avoid the use of arteriography or invasive techniques. Partial venous inclusion is frequently difficult to diagnose as the symptoms may vary from none to deterioration of renal function, hematuria and massive Proia depending depending upon the degree of obstruction. The recommended treatment for partial venus seclusion is he? While immediate surgical intervention is required for complete obstruction of the arterial of venus anastomosis if success in our graph survival is expected. Although the problems encountered with graphs that have multiple vessels are not truly vascular complications. The increasing use of such graphs especially from living related donors makes this subject worthy of further discussion. First, slide when small polar vessels such as one scene in this slide are present. Past reports indicated that they could be safely located if they appeared to supply only approximately 10% of the renal graft. In the past, there was also a reluctance to utilize kidneys from living related donors with several renal vessels due to the multiple sometimes difficult anastomoses and the prolonged ischemia time encountered to complete these animes. The University of Minnesota recently reviewed their experience with the use of living related donors that had multiple vessels. They concluded that living related donors did slightly better than those with multiple vessels. But those donor grass with multiple vessels did significantly better than cadaver grass with single vessels. They also concluded that ligation of small polar vessels resulted in a greater instance of complications and a more serious and more serious rejection episodes. It was their conclusion and recommendation that vascularization of all arteries should be performed if at all possible. A number of interesting techniques have been devised for this purpose. The first, I think I'm sure you, most of you are familiar with is use of a corral patch and cadaver transplants which has been done for several years or for a prolonged time. Dr Belser has recently described the obstructive effect of suturing a small thin wall vessel to a larger thick wall vessel. He has devised a technique to avoid this constricting effect by constructing a type of corral patch, utilizing a vein wall has demonstrated on this slide. This has been successfully used by myself and by other surgeons. Other methods include suturing small accessory arteries to the large renal artery. If one is present or this could be done in the case of three suturing both to the main renal artery. I have done this on one occasion and found it very satisfactory when a short renal vessel exists a vein patch or a vein graft or even a small artery from the donor can be used to extend the length for either swinging it up for the Anestis shown in the upper portion of the slide for inclusion of a double Anestis to an iliac vessel, whichever seems to, whichever is the most easiest is easiest at the time. Or another technique when you have two vessels of a similar size is to suit the two vessels together, forming one and thus one and assis frequently this is a nice technique to utilize when you have a large hypogastric artery and two small or two equal size vessels. When multiple renal veins are present, small veins can usually be safely ligated. If there is one large renal vein. And due to the rich in renal venus and asses, if there are two renal veins of approximately the same size, then it's probably best to revascularize both as the ligation of one of such veins can sometimes result in massive protein area as seen in one patient reported from the Medical College of Georgia. If there is damage to the renal vein during the framing resulting in an excessively short length of vein. The following technique has been successfully used to revascularize the graft with minimal difficulty. Ring artery stenosis is being reported with increasing frequency. Clinically. This lesion is usually associated with a brewing over the renal artery, uncontrollable hypertension and deterioration of renal function. Thrombosis has also been a complication of renal artery stenosis. The value of R levels and diagnosing this lesion in the face of hypertension is a is remains a controversy and the exact role of this test at the present time is undetermined. Doll recently described two types of renal large stenosis angulation and segmental angulation, stenosis. He attributed to excessive vessel length and binding adhesions. He described three patients in his series with this lesion whose hypertension was relieved by release of the adhesions. Segmental stenosis is the type most frequently seen and it's characterized by stenotic area occurring distal to the patent anastomotic area, vessel damage due to either flow dist services or immunological reaction have been considered as a possible ideology of this tono lesion. The methods of repair include vein patch, angioplasty vein vein, uh bypass graft are a primary excision of the sona area and this is a slide of one of our three patients who have developed surgically correctable lesions and this lesion is a very tight stenotic area which is distal to the anastomosis. All three of our patients have been successfully treated by primary excision of the stenotic area and re Anestis of the vessel. All three had sustained hypertension refractory to anti hypertensive medication and breweries that developed late in their transplant course. We've had two other patients who have developed renal artery problems both related to hypertension. This particular patient had a correctable lesion, although it would have been correct with great difficulty as it was in one of the branches of the renal artery. The next patient had a lesion that was not correctable and it was intrarenal. But I don't think we could have surgically corrected either of these lesions without a significant risk to the kidney. Fortunately, both of these kidneys, both of these patients hypertension could be controlled with medical therapy and further treatment or further surgical intervention was not necessary slides off, please. Disruption of the vascular estos occurs and has been reported. But this complication is almost always associated with infection of the su line, except in unusual circumstances, the graphs should be removed. In summary, the vascular problems encountered in renal transplantation are varied and require thorough knowledge of the techniques and principles of vascular surgery on the part of the transplant surgeon and sometimes a rather creative imagination. I must confess in my experience, there have been multiple occasions when I wondered if the creative imagination was not the most important technical problems vascular with John D Welchol. Lieutenant Colonel US Air Force Medical Corps Chief Transplant Unit, Wilford Hall, us Air Force Medical Center Lackland Air Force Base was produced through the mobile facilities of the television division, Academy of Health Sciences. United States Army, Fort Sam Houston, Texas.