*This machine-generated transcript may have errors. If remediation or a manually-generated transcript is needed, please contact NLM Support at https://support.nlm.nih.gov.* we're gonna talk today about double contrast examinations of the gastrointestinal tract for the non radiologic people here in the audience. Some of this will probably be review, some will be new material and I hope hopefully it's timely as virtually everybody at one time or another does order gastrointestinal studies on their patients for a variety of reasons. Obviously this is basically a radiologic talk, but I will orient as much as possible to it, to the clinicians uh when appropriate times make themselves available. I have really two themes that go out through this entire presentation and that is um double contrast techniques may be performed by any interested radiology department. They are not difficult to do. The reason I tell that to you clinically is that if you're ever working at other institutions and perhaps the radiology department is not perform these techniques, you know, that they can be performed with these. There there may be reasons why they don't perform them or differences in philosophy, but they can technically be performed readily. And the second theme is that uh at least in my opinion, in many instances, the diagnostic capabilities of G. I tract radiology are extended with these techniques. So, if we could have the first slide and the lights down, like double contrast examinations of the gastrointestinal tract can be performed virtually the entire gastrointestinal tract, the esophagus, the stomach, the duodenum and colon colon air contrast work has been known about for some time now, primarily popularized in uh europe. However, I think in this country it's been generally somewhat under utilized, but now there are techniques available to study these various sites with these techniques. Next line first, we'll talk about the esophagus and we'll follow the gastrointestinal track ab orally. There are various techniques that may be utilized in the technique that we have utilized here with considerable success is using the patient upright and having the patient hold barium in one hand and a cup and water in the other hand, patient has a mouthful of barium and then swallows the barium and quickly thereafter one mouthful of water so that you see we do not produce an heir contrast effect but rather a double contrast effect. That is the water washes through the barium that has previously been swallowed. Leaves a coating of barium on the esophagus and produces the double contrast effect we use for the variant preparation preparation that is formulated for air contrast colon work. It's a preparation that's a moderate moderately viscous and has excellent coding properties and spot films are obtained at the appropriate time. Next slide. This is a subject holding the barium in one hand and the water in the other hand taking a mouthful of barium. Next slide patient has the berry um in her mouth, water is ready and she's going to swallow the barium and follow that with a swallow of water as quickly as possible so that the water as we said, can wash the barium through next line. This is an example then of a normal double contrast to Sasha graham. A good one obtained with this technique. Next line. These are the clinical and radiologic uses uh for double contrast to soften biography. I should point out to you when when you're ordering this in your patients, we don't do this routinely. We do it if there are so fragile symptoms and or if there is a suspicious finding on a conventional esophageal examination. So it is not a routine examination in our department. As several other of these techniques are. It's obviously helpful for the detection of small esophageal tumors. I don't know that these small tumors are always early tumors, but one can detect smaller salvageable lesions with reliability. With this technique, it's helpful to delineate the morphological features of lesions in the esophagus. That is the surface characteristics. Is it smooth? Is it irregular? Is it also rated? And finally, to distinguish between mucosal and sub mucosal lesions? And I'll show you some examples of these things. And another use for this is to assess the total vertical extent of disease that is you have a neo plasm. The total vertical extent of this new plasm can be readily assessed with double contrast to soften geography. And this is obviously going to be helpful in treatment planning. Next line, this is an example of a lot dilated esophageal carcinoma that we had some time ago and this lesion would not be missed and was not missed on a conventional, say photography, but one can see it uh very readily with a double contrast technique and can tell the gross vertical limits of disease very readily here, much more readily than on the conventional technique. Next line. And this la belated mass in these various projections as an example of a carcinoma sarcoma. Now these several lesions no one is going to miss with conventional techniques, they're obvious. I think there may be more elegantly displayed here and one can see a little bit more about them. I'm gonna show you some cases now where the double contrast technique was of definite value in comparison to conventional techniques. Next slide, This is a man that was being followed here for a gastric ulcer. He was referred here because it was felt that the gastric ulcer might be malignant and he did have a gastric ulcer, had a symptomatic patient in terms of his esophagus and on his esophagus, RAM had this obvious uh filling defect here. It's difficult to characterize it, but a definite filling defect there on multiple swallows. As you can see next slide and here with a double contrast techniques, we can see this lesion in profile and then interestingly we can see it on Fox here. It's a little unusual to see in esophageal lesion on fox, but this is analogous to how we see Palepoi defects in the colon. And this is a squamous carcinoma in this patient. I think that we can see this uh lesion considerably better with this technique than with a single contrast next live here's a very interesting patient and we'll use it to make another point to clinicians. This is a patient who had had a previous head neck tumor several years before he had a carcinoma of the tonsils and he was having difficulty swallowing and he indeed was having difficulty swallowing. You can see here that he's aspirated a fair amount of contrast material. We could not obtain very many films of his thoracic esophagus. But in this region once he's a little mucosal nodule and this proved to be a squamous carcinoma of the esophagus and a patient with a previous head and neck legion next slide and another more recent patient, another patient with a head and neck lesion a few years before. Again asymptomatic just being studied routinely for his head neck problem. We see this plaque like irregularity along this wall and this has been proven now to be a squamous carcinoma of the esophagus. I want to just stop here and make this point to any of the clinicians that are here who do see patients for head and neck problems, not necessarily head neck surgeons or E. N. T. People but anybody who comes in contact with these patients at the time they are initially diagnosed and thereafter when they're followed up one of the routine things that should be done with them at some regular periodicity. Maybe like every six months after the baseline examination is to do in a sofa graham because there is a definite increased incidents of esophageal carcinoma in patients with any sort of squamous head and neck tumors. And we have found a large number of them in a several year period of time where we've been looking maybe maybe about as many as a dozen. Some of them quite small and others unfortunately, very large, bulky tumors. So this is an association, I think that it hasn't been entirely recognized here and then we need to look for it and maybe just as common as these people later developing squamous carcinomas of the lung. Next slide, another patient, this patient on multiple barium swallows had this vague area of narrowing in the esophagus. It was definite but not hard to characterize it. Next slide, mucosal pattern through this area was entirely normal. Next slide, but on a double contrast study, we can see some additional findings on the left here, we can see some shouldering effect that wasn't appreciated on the barren field study. And we see some irregularities on the contour of the esophagus on the opposite side. And this is another squamous carcinoma of the esophagus. Next live, here's an interesting patient. This is a brother of a physician here in this hospital who had this vision was examined at another hospital and had this filling defect in the esophagus. This filling defect identified. He was referred here and had some studies done here. Next line on this double contrast study, we see this nice smooth interim euro lesion. If you look very carefully here and I hope it projects There's another thing staring at us on foss. Next live turning the patient into the opposite of liquidy. We see the other lesion. Yes, sir. Are to lie on my mama's in this patient's esophagus, only the second one being recognized with double contrast study. Next slide, here's another interesting patient that has this obvious fungal irregular carcinoma with some extension seems to be going up into the esophagus as they commonly do. Next slide films of the esophagus do show some minor marginally regularities. And one would be suspicious that there is disease there. But it's a little hard to define next line. But again, with double contrast study, we can readily outline the total vertical extent. This is not a good study because this patient had relative obstruction here. One can always obtain a beautiful study. But even in a study here that somewhat compromised by an obstruction, one can still see this Neil players from crawling up the esophagus. This piece of tumor is up here. So we can see that virtually the distal half the esophagus is involved by this gastric nia plasm that's readily identified with double contrast examination next lot. And finally, just in terms of inflammatory disease. This is a patient with candid diocese and we see a nice cobblestone pattern throughout the assad because in this patient next line. So in summary relating to the esophagus double contrast of so photography is simple to perform. We do the technique of barium and water with successive swallows and we find that it is a useful adjunct to the morphological examination of the esophagus for the detection of small esophageal tumors. Hopefully early in some cases defining the morphological features of the tumors and finally the vertical extent of disease in the esophagus. Next slide, we'll go on to the stomach now and talk about air contrast or double contrast exams of the stomach. In this case, the way the technique is performed on your patients. We use 2-3 ounces of a high density berry. Um that has certain coding properties for the stomach to the barium is added an anti foaming agent that we'll discuss in a moment and we use a gas preparation effervescent powders to produce the gas in the stomach patient ingested the gas preparation the effervescent powders and follows this with a barium patients turned several times to make sure the stomach is coded and to dissipate the bubbles and then double contrast views are obtained. We routinely do four double contrast views in our examination and it's readily incorporated into the initial part of the examination. Blue dragon and other anti spasmodic agents may or may not be added uh to decrease gastric peristalsis uh and decrease gastric emptying if that's necessary. And we use a low killer voltage on these radiographs to obtain optimal contrast next line these are some of the preparations that have been available primarily manufactured in japan effervescent preparations and many of these had anti foam substances in them. However, they are generally not available in the United States. Uh at this time. Next slide, this is one of the preparations call unique Zorro. We see here that when the cap is opened, there are some japanese script here. A lot of people think that this is the instructions as to how to do the examination, but others feel that this perhaps represents new plans for an attack on Pearl Harbor. Next line we find that just plain old citric carbonate that one can obtain from any pharmacy is just as good as the other preparations of course here where there is no anti foam agent and one has to add the anti foam agent. We use about a teaspoonful of the gas powder next line and we add Millikan drops. In other words, this is signed with a cone to the berry, um maybe a CC or CC. And a half of these malecon drops are added to the 2 to 3 ounces of barium. Next line, yes. So the patient begins the examination with citric carbonate powders and bury him in hand. Next line she ingests the powders and drinks down the uh the barium patients place in a recumbent position and turn from the supine to the prone position and back three or four times again to achieve as good at coding as possible and to uh make the bubbles disperse that are formed by the citric carbonate. Next line and then three films in the supine and soup. I know black positions are obtained in rapid succession. One wants to do this fairly rapidly so that not much gastric emptying of either barium or uh air takes place. Next live. This would be an example of a nice double contrast gastro gram in the supine position with just a small amount of barium and not much gastric emptying. Haven't taking place. Next line. one Old Black View. Next live the other old black view. Those are three routine views we obtain. Next lied at this point we stand the patient up and obtain an upright view of the fungus. And at this point then the rest of the examination is resumed as in a conventional way. And most people would at this point do pressure, mucosal views on the on the rest of the stomach and there's just a small amount of barium in the stomach at this time. And one can readily obtain these views. Next line, I'm just gonna digress here for a moment and talk about one aspect of the stomach anatomy that we've been able to appreciate with double contrast studies of the stomach. Should say that dr Dodd stimulated this work in our department. He has been interested in this for some time. And for any of you who are further interested in this and other aspects of stomach anatomy. He's going to be talking at jesse jones library building on the first floor to the Houston Gi Forum this afternoon at three o'clock. The surface of the gastric mucosa, my gastric mucosa and yours. Everybody's is subdivided in addition to the Rue Guy that everybody knows about into small ovoid or political islands by a complex intersecting series of shallow grooves. The islands that will show you in a moment or turned the area gas tricky and the surrounding grooves are turned the salsa gastric next lot this is a stomach that's been opened up. And if you look carefully, you know, there are obvious ruby. I hear that everybody knows about in the stomach of course, and that we use to make diagnoses with. But there are other little islands here. In other words, a fine mucosal relief pattern in and amongst the Rue Guy and where the rug I are not in the stomach. Next line, this is the same stomach painted with barium and one can appreciate this network pattern uh in the stomach amongst the Rue Guy and in between them and on them, et cetera. Next line here is a close up of one aspect or one portion of the body of that stomach. So like here's a gastric crew guy. And there's one and then one can see on the Rue Guy and in between them these little political islands of tissue, the fine mucosal relief, the area gastric and then surrounding and actually making up these little islands are these intersecting grooves called the salsa gastric E. Those salty gastric. Those little tunnels is where the barium goes to make that network pattern. Next line. And this is a close up in vitro painted view of that portion of the stomach showing that appearance. Next line. Dr James Anderson in uh the laboratory associated with the diagnostic radiology department. Uh did some scanning electron microscopy of some stomachs. And this is an interesting appearance of this pattern with a scanning electron microscopy. One of these is an area gastric E. These are one of these islands blown up. And here are these tunnels. These intersecting grooves the salsa gastric E. And we can notice. Then each area gastric itself has a convoluted patterns like each area gastric has an area gastric pattern of itself. But we see a convoluted pattern on each area. Gastric Next line here's a close up of one of those. This is one area gas tricky. Here are these tunnels alongside the salsa gas tricky these grooves. Okay. And then we see this convoluted pattern. If you notice amongst the convoluted pattern, our little pits, little depressions. Those are the gastric pits. Those are the openings on the gastric mucosal surface into which gastric glands drain so that if you can see here each area gastric E. Each little island maybe has a dozen Of these gastric pits into which gastric Glands one or more drain next slide. So this schematic drawing summarizes what we've just said. Then one of these islands is the area gas tricky. And then one can see these little black dots representing the cell site. Excuse me representing the gastric pits. And then we can notice here in the cross section. One or more gastric glands drains into each one of these gastric pits. Thanks line Radio graphically we can identify this pattern if we do double contrast techniques and have good coding variant preparations that are not too viscous so that the the barry um can enter the shallow sell side gastric. And we have identified three arbitrary patterns. We've talked about a fine pattern, a course pattern in a nodule or pattern. And you will see this in your report sometime where we talk about a course fine mucosal relief pattern or a coarse or fine area gas tricky pattern. Next lot here are some examples. This fine little network pattern in the distal stomach here is an example of a of an average fine gastric find relief pattern. This would be uh not very spectacular. And we see this I guess in about 50% of our cases uh using double contrast techniques. Next live this would be a coarser pattern where the islands themselves are larger and the grooves themselves are denser appear more coarsened. Next line. Another example of a course area gastric pattern. Next line and finally a not very frequent appearance, the nodule er appearance of the fine mucosal relief pattern of the stomach. Now, uh anatomically this is interesting and I think certainly one thing it helps us with is that if we see this with regularity, we know, then we have an objective criterion to say that we are achieving excellent double contrast examinations of the stomach. If one can see this pattern, one knows he's achieving ah good double contrast work of the stomach what their functional significance is and if they can be used in diagnosis is a little more questionable at this time, we have had some cases where the pattern's been course or Nigel er that has been diagnosis gastritis. We've had one or two cases where it's been helpful in malignant disease, but at this time it would be hard to make a definitive statement about its real diagnosable value. Well, sometimes in our reports say this to the clinicians, you'll see a report that discusses this pattern the fund because of relief pattern of the area gastric pattern. And there will be a statement made that it could suggest diagnose of gastritis and you have to correlate that clinically with your clinical findings. But at this time there is no definitive statement that can be made regarding its its functional significance as diagnostic significance. Next line, okay, now, back to double contrast gastro graffiti and some quick examples of diagnoses that are made very readily with double contrast uh studies here on the post year. While the stomach is the evidence of a healed ulcer with multiple radiating folds right into a little gastric pit. Next slide here's another lesion on the posterior wall of the stomach, a central ulcer crater with radiating folds. This surprises. Incidentally, one can see this network pattern the area gas tricky and the more distal stomach. We thought that this, you know, in this projection at least had the appearance of a benign ulcer with radiating foals dr nelson and his group endoscope this patient and took some biopsies and I understand that on this one or two of the folds up super early there was lymphoma patient did have known lymphoma in his liver and this turned out to be a lymphoma. This involvement of the stomach and this unusual presentation of a ulcer with radiating folds. Next line, here's a very interesting case. It's not something that's going to be seen very much probably at this hospital but will be seen at other hospitals where this technique is performed. This is a standard right Ontario black view of the stomach that's perfectly normal in a patient. Next line. This patient, if you notice on the double contrast study has multiple punk Tate and linear collections of barium. Next slide, I think there's a close up in a different projection. Multiple punkt eight and linear collections of barium and many of the punk take collections are surrounded by nuisances. Can we go back to the other slide out and it seems from here. It projects a little better. Many of these little collections are surrounded by licenses and this is a pretty classic radiologic example of erosive gastritis with multiple fine linear and and dot like superficial ulceration surrounded by small halos of oedema. And this is a diagnosis that can be made only with this technique and with some frequency according to the literature. Again, we don't see that kind of patient here. Very often, I should comment at this point that these techniques were originally evolved in Japan primarily. Certainly they were popularized from Japan for the earlier diagnosis of focal, non invasive carcinomas in that country. And judging from the literature and from our own experience here, although it may be a little skewed by the type of institution that this is, we don't find many early malignancies, certainly not add no carcinomas with this technique that may relate to the fact that we don't see early patients or that gastric carcinoma is not as common a disease here as it is in japan or perhaps to some extent the fact that we are not surveying patients in this country for this problem as is done in many parts of Japan. So I think that the yield in gastric malignant diseases not nearly going to be as high as it is in the orient. However, there are diagnoses that are made in this country? Uh that are coming here that can be made really only with this technique and that's why I stopped here. This is such a diagnosis. The case of a gi bleeder bleeding from erosive gastritis. Uh This is going to be a high yield diagnosis with this technique uh in the United States and north America in general. Next line and the next a gastric polyp. Next line and another gastric pile up and we can see her again the network pattern the area gastric pattern that you'll see discussing the reports periodically. Next line here's a pretty obvious case. Uh I don't think one is going to miss this with any technique large sub mucosal mass and other nodule. A rude guy representing lymphoma in this patient but a very elegant example of the entire extent of disease in this patient's stomach. Next line, another large ulcerated mass. On the lesser curvature. This was an adenocarcinoma. Next slide now we were talking about primary malignancies. We have had a yield in about three or four patients of one form of malignant disease in the stomach. Not diagnosable with conventional techniques. And here is such a case. This is a single isolated metastatic melanoma deposit on the greater curvature of the stomach that was only diagnosed on this film with double contrast techniques. Next slide and another more recent case. In this upright view of the fund is there is a small sub mucosal mass in this patient with melanoma, isolated lesion. So we have had yield in this form of malignant disease although not primary malignant disease. Next line okay that finishes discussion of the stomach and I have a few brief words now on the duodenum. Hi platonic doing ethnography. That is the use of a pharmacologic agent to paralyze the duodenum and obtain better films of the duodenal pancreatic interface has been uh pretty popular in this country for about 10 years or so now. And uh air contrast portion of that exam is is a routine portion of double contrast of high platonic doing ethnography. And here is an example of a paralyzed duodenum with a nice perry ambulatory or perry vegetarian duodenal diverticular one can appreciate the very nice mucosal pattern here is the longitudinal fold extending down from the area of the ambulance. Uh So this is certainly a very helpful technique not only for the diagnosis of disease and the head of the pancreas, but for primary duodenal disease as well, it's gonna be helpful in ulcer disease and occasional duodenal tumors as well. Next line indications for this exam or if a conventional upper G. I. Series is suspicious for primary duty or pancreatic disease. And if there is a strong clinical suspicion of pancreatic disease despite an apparently normal upper gastrointestinal uh series technique can be done with a tube or without a tube and uh we have done them both ways in the department. So this is a technique that you can order on patients where you fit these indications. And very often we will just incorporate it into our examination when uh when that is necessary to come to a more accurate diagnosis. Next line, there's an interesting patient we had not long ago. This is a patient who had a lot of nice spot films of duodenum and had an apparent pad effect or mass along the medial contour of that duodenum do deny graham was performed next slide, which is perfectly normal and shows us that this pseudo mass appearance was formed by this longitudinal fold extending down from this somewhat prominent and pula. So sometimes normal anatomical variants in the duodenum can be mistaken for masses and can be resolved with HIPPA tonic doing ethnography. Next line and this is an example of a carcinoma of the excuse me of the duodenum with traction changes. I hope you can see that. I can't see it too well from here, traction changes on the duodenum in this portion. So air contrast work is a, let's say, a routine part of hip a tonic doing ethnography and not infrequently the air contrast films uh are the highest yield among in the examination performed with a high platonic agent of the duodenum. Excellent. Yeah. Next line. Well all that's been good. And we've talked about the upper gastrointestinal tract. But now we really come to the money and that's the colon at least the money for neo plastic disease. This is really where I think we can most help our patients here is a place where when we say a small tumor, we almost talks anonymously with an early tumor. Unlike other anatomical parts in the gastrointestinal track in other areas of the body here. A small tumor is means early tumor. And we want to be able to make the diagnosis of small uh colonic tumors. And let's talk about the colon preparation. And let me say to you, although you know this, you know, this is the most important part of the examination. This is the whole thing. In fact, the exam is not very difficult and it doesn't require particularly sophisticated equipment, but you do have to have the colon prepared in some ways, colonoscopy, which we'll talk about in a few minutes, which has come in some centers to rival uh, barium studies of the colon really has done us a little bit of help there because clinicians now at least people are doing colonoscopy realized that when we were talking about all the filling defects in the colon really can be a problem making a diagnosis. So they colonize space, appreciate, appreciate now the value of a clean colon, the entire colon. Um, please please please please please encourage your patients to take the preparation. Don't tell him our it's okay if you skip something, you know, encourage them to take the preparation and we'll discuss what we use here. You know, the preparation is I'm not saying it's the most pleasant thing to get up in the morning and go and have a very minimal, but you know, it has to be done, you know, it has to be done and we want to do it well and help the patient. So please encourage your patients to take the preparation. Okay, that's number one. Number two. Um four patients who are in patients in this hospital, we are unable to write for routine, very minimal preparation. The orders have to be written out. Well, there is in every nurse's station at this hospital, we've checked any number of times, at least one copy. If not more of our routine barium enema preparation, follow it, sit down with it and write it into the chart. I don't say it's a pleasant task, but it has to be done. So follow it on your impatience. If there's any question as to why a patient can't take a preparation, You can call us, you know, you can call us the department and we can discuss it and we'll modify it if necessary, but please write for our entire preparation. So we don't have a compromised exam. Let me tell you that. We will not hesitate in the radiology department to cancel the patient's examination. Uh If he has not taken a preparation or it hasn't been ordered for him as an inpatient. We do our best to, you know, to accomplish the examination. We will will go so far, we'll give multiple enemies in our own department. But you know, we need cooperation. We don't feel we're going to do the patients a favor or you a favor if we do an inadequate examination and MS a potentially curable colon lesion. And another point I want to make before we look at some cases is that many times you may order a barium enema and we'll do an air contrast or occasionally vice versa. Please give us adequate history on the requisition so that we can make a reliable judgment as to what kind of examination the patient needs. There are certain indications that we follow that I'm going to show you in a few moments. And uh if we don't have reliable history written down there or we can't communicate with the patient, it's difficult for us to make a good decision about what examination is best for that patient. So uh please give us adequate history so that we can make the judgment. But you will find times when a conventional enemy is ordered or just it's written barium enema and we do in air contrast and occasionally vice versa. But we do what we think is most indicated to make an accurate diagnosis in that patient after we've talked to them and seeing the history requisition. So this is the colon preparation that's used in this hospital. We do our upper jeez first and we have done that for the last several years. And here is the rationale, I've had a lot of phone calls on this if a patient is going to have both exams that is an upper gastrointestinal series and a barium enema. We do the upper gi first, our scheduling people know to do that. And the reason we do that examination first is so that we use the berry um that they've ingested as a marker to tell us if the colon is clean. That is to say if a patient has an upper gastrointestinal series on monday of a given week and on Tuesday they begin their colon preparation on Wednesday morning. If there is any significant amount of barium retaining their colon, we have an opaque barium marker to tell us that the colon is not clean. That is the rationale for us doing a upper gastrointestinal series first in most routine patents obviously if there is a suspicion of colon obstruction, we don't, but in the routine patient that's being worked up for bleeding or whatever. Upper gastrointestinal series is done first. It's basically an 18 hour preparation that begins at noon the previous day and it consists of hydration. You got to drink a lot of water juice, a minimal low residue diet at eight p.m. The patient takes magnesium citrate at 10 PM. Doug relax pills and the morning of the examination, a dull colak suppository. Probably not the best thing to have to do in life but you know, it's an important preparation and with this preparation we can get most Coghlan's clean. Occasionally it takes a second day in patients who are particularly not ambulatory. We do have uh facility and we'll have further facility I guess in the new department dr Dodd as uh designed for a uh enema to be given to the patient uh if possible and we'll give those in our department, I must say relating to air contrast work. I personally don't like to do animals prior to air contrast work because most patients don't evacuate of the water and can affect the coating of the burial. But others do do this routinely. But we rely primarily on this preparation. So please make sure as much as you can that the Coghlan's of your patients are prepared so that we don't do them injustice and make an inaccurate diagnosis. Excellent patients done prone, we run bury him into part of the colon, shake the berry um into the rest of the colon, drained the rectum and put the area. It's a very simple technique that can be be done can be done in any radiology department and then a number of radiographs are obtained both spot films taken that Flora's copy and what we call overhead radiographs taken by the uh technical people. Again, this idea of low killer voltage, which means higher contrast on the pictures. Next line, these are commercial burying preparations that we are now using for a time. We were mixing several commercial bearing preparations. But now there are good commercial products available for all of these techniques to use. This comes as a liquid and we just poured into the bag and put that into the patient's colon. Next this is the enema tip. It's a soft plastic enema tip and piggybacked into the enema tip is a fairly large bore needle, like a 16 gauge needle that's tips just right in through the enema tip into the aluminum, aluminum, the enemy tip and stigma nanometer bulb introduces the air when we're ready for that. So the barium goes through here and the air through here. Very easy setup. Next line, so this is about ready to begin the bag of barium with large bore tubing so that this moderately viscous barium will flow through and patients began prone. Next line we said that barium does have to be squeezed in next line and the Baron's run so that the colon is approximately halfway field. Next line and the patients turned on the right side and shaking a little bit and usually this will advance the barium into the right colon and we'll go ahead and drain the rectum. Next slide after the rectums drain will instill the air we put as much air in as the patient can reasonably and comfortably tolerate or until reflux into the small bowel occurs and then we begin to take spot films at that point we'll take spot films of the rectum. Next line. Let's take spot films of the fletchers. These are done in the upright position, many of them. Next live spot films of the Sikh. Um There are certain anatomical areas in the colon that we spot in various positions. Next line and then large overhead films are obtained by the technician. Supine films. Next line, upright films. Again, these are particularly helpful these upright films and to cuBA to films that I'm gonna show you particularly helpful because if there is a small amount of fecal residue remaining in the colon, if it's free, freely moving and not attach the wall with these upright films that fecal material will fall into the Bering land. We can resolve whether an area is normal or abnormal. With these techniques. Next line and this to cuBA's position that is the patient laying on his side and the x ray beam directed horizontally at the abdomen patient in this case was laying on her patients right side. Next line. Just a word about colonoscopy. Uh There's been, I think in the medical and surgical literature in the last few years, a fair amount of competition between radiographic examinations of the colon and colonoscopy. Most of these have been written by uh gastro neurologists and surgeons, particularly one group in new york and they have kind of condemned the barium enema examination. Well, I think that dr nelson agrees here I think and probably this is the appropriate, the appropriate ah point to make on it is that they are complementary exams. That's kind of almost a trite statement about so many things. But I think in this case is true. There are some things that we can do that colonoscopy can do. For example, colonoscopies can't get to the seek them every time. And we always can if there's an obstructing lesion of colonoscopies can't get by it. And we usually can to see if there are other lesions in the colon. And there are things that colonoscopy can do or detect that we can't detect not to mention the therapeutic applications of uh colonoscopy. So I think they are complementary techniques and uh should be considered. So, certainly from a on a screening basis. Uh you know, the time and money involved in doing screening, colonoscopy is, you know, be virtually impossible when in comparison to uh barium study. So, the barium barium enema examination, as has been said by a number of people. It's not a bad example, a very fine examination. It's just not always done well. And part of that is our own fault perhaps is the worst radiologic examination performed in the United States, but we take responsibility for that. And uh but you need to take some responsibility too and ensuring as much as you can that your patients do take the colon preparation and that their Coghlan's are clean next line. So some examples of uh of the colon here is a classic podunk related polyp in this patient's descending colon next line. Yeah. And here, seeing this on fox is a cecil polyp. Next line along the right colon here, I hope you can see them are a number of small polyps. We will routinely find little polyps or Palepoi expressions is 123 millimeters in size when we have a good clean colon. And are studying patients very often, they're not symptomatic in regard to bleeding or what one would expect from polyps. And sometimes we don't really know what to do or say about little polyps like this, but we will document them and put them into the patients record. So that's certainly at a later time. If the patient is re examined or become symptomatic, one can direct his attention to that area. But fairly routinely one will follow. One will discover small 1 to 3 millimeter polyps in the colon. Next line, typical annular apple core carcinoma of the distal sigmoid or rectal sigmoid colon. Next line here are the indications that we use in this department and are generally used by people who advocate um Double contrast examination of the colon. Certainly rectal bleeding is an indication of the classic indication for air contrast colon examinations. Also other symptoms, ontology or findings, constipation, anemia, weight loss. Those things that might suggest a colonic malignancy pilots having been discovered on a practice ka pik examination or any other kind of an examination. Any previous history of polyps or cancer of the colon. Any kind of history like that leads us to do an air contrast examination. Any family history of polyps or cancer. And I'm not even talking about Paula poses of the colon. Just a family history of polyps or cancer. And then certainly previous colon surgery For polyps uh cancer. We all know about the increased incidents, maybe 5% associated frequency of synchronous and asynchronous carcinomas of the colon. So we're looking for the second lesion, the second smaller leading to make sure that the operation is complete. These are the indications we use them for many years patients that you send to us for with pelvic mass. Uh Those don't normally get air contrast in the department unless there are other symptoms patients who've had radiation uh probably having symptoms from radiation practice practice. Sigmoid itis don't usually get uh air contrast examinations. And also if the patient has an unknown primary where there is already known malignant disease to deliver to the bone to the notes. Very common patient in this hospital. Those patients don't get air contrast. We feel that we'll find the tumor if the tumor is the unknown primary, we'll find it on a conventional examination. Next line, here's an example of a carcinoma of the recto sigmoid colon. We have a nice feature of it in denting the wall from which it arises or pulling in the wall from which it arises. A small carcinoma. Next line a plaque like carcinoma along the posterior wall with the rectum. Next line, here's a lobular mass in the ascending colon that represented a lie poma. Next line, here's a case that was lent to us by dr horrible from Hermann Hospital that illustrates this. This was a barium study done on a patient and the sigmoid colon in this region does look abnormal, looks very peculiar, but it's a little hard to define. There is kind of a scallop defect here, but hard to define what's going on there. And appropriately, air contrast study was performed the next day or several days later. Next slide and the question is resolved. There is a carcinoma of the colon, a cecil carcinoma of the colon here and then in addition, there is a large sentinel polyps in this region that arises from the colon wall adjacent to the carcinoma. It's said that as many as 5% we said, 5% of patients have multiple invasive carcinomas of the colon. Another 12% of patients who have won carcinoma will have associated polyps or carcinomas insight to and as maybe as many as 40% of patients that have a carcinoma will have at least one other polyps in the colon may not always be adjacent to it in some other place in the colon. So it's very important to do a complete examination prior to surgery. Next line. Now here makes a point that we're kind of talking about here was a patient that was referred in for this obvious annular apple core carcinoma of the sigmoid colon. But as we looked around this colon, there's all kinds of filling defects in another carcinoma. Up here and here's a place where colonoscopy will be very valuable but wouldn't be able to get past this obstructed area. So, you know, this is an example of where a radiology is important and where colonoscopy uh can't be of much use past this area. And there are examples to the contrary, of course. Next slide, this same patient also had a third carcinoma in the Seattle area, descending colon, cervical area. So this was a patient with three carcinomas and multiple other polyps and only one identified on an outside study the major annular carcinoma. Obvious one next line, here's another interesting patient we had not long ago with this large villas tumor right here that has an obstruction. But if we look over here in the ascending colon, there's another lesion. Next live, here's a close up of this beautiful villas adenocarcinoma of the colon with these. This is has a network pattern to caused by the very um being trapped and interspersed among the fronds of the villas tumor and this angular component of the tumor indicating it's malignant nature. Next slide and then a close up of this lesion in the ascending Siegel region. Another example of double primary is not uncommon and needs to be examined. For next slide example of Paula poses of the colon. This happened to be a patient with Gardner syndrome. Next live cone down to you to see them. This is kind of the classic examination. Everybody knows about air contrast colon examinations for but it has obviously many other uses. Next line, another case of paul opposes the colon with a somewhat different appearance, more of a carpeting appearance. Next lie, here's a gross specimen on that patient. Next line, the first patient had no malignant tumors. This particular patient, this last one had three areas of Dominant mass or carcinomas in his colon. This was one of them in the rectum. There were two others. Next line. I hope this project again. I can't see it from up here but this is an entity seen in Children with some frequency called lymphoid hyperplasia. It's common in the terminal ilium and it's also very common in the colon. And these little filling defects can look like pops but should not be mistaken for polyps. These patients are usually asymptomatic and one doesn't want to perform a collecting me on these patients for benign lymphoid hyperplasia. Next line and here's a most unusual case given to us from texas Children's hospital recently of a long juvenile pilot just showed it because of its unusual nature usual appearance. Next line now we do uh air contrast work occasionally for benign disease. Uh but not not always. Here's a patient. An interesting problem that was resolved. Benign diseases. Patient had this filling defect in the cycle tip on several outside uh conventional studies. Next slide and with double contrast, we can see this smooth filling defect and this turned out to be an intercepted appendix patient had not had his appendix out. It's just that his appendix was intercepted and causing this smooth sub mucosal defect in the single tip next line. And here's an example of diverticulitis with multiple diverticular here and a sigmoid vaginal officially diagnosed by double contrast, this patient had rectal bleeding and was not suspected of having diverticulitis and that's why the patient had an air contrast. So one can use this technique to diagnose diseases such as diverticulitis, but this would not normally be an indication for uh double contrast work next line and inflammatory bowel disease. Again, we don't see too much of that at this particular institution, but some people have advocated for the more accurate and earlier diagnosis of inflammatory policies. Here is one such case. This is a spot film taken in the distal transverse colon and one sees this cobblestone pattern. Next slide and in the ascending colon there were four areas in this patient's colon. You are seeing two of them of this. Finally, Nigel er cobblestone appearance in this patient with Crohn's disease. Of the colon. Next line finally, we're gonna spend a few moments talking about the post operative colon. We said that one of the indications was in the postoperative patient to find the asynchronous arm attack Cronus carcinoma and one can do this in any type of post op patient. This is a patient that had a primary anastomosis and one can visualize the nest emotions very readily with double contrast techniques. Next live and here is a patient who had a right hemi collected me and one can see the elio transverse colon anastomosis. Not to mention looking at the rest of the colon. So we do this in all post op patients where we can next line and we've also been able to evolve a technique here of examining colostomy Coghlan's with air contrast techniques. We do that by asking the patient to insert a soft rubber catheter in through their colostomy. Similar to their irrigation practices. We tamponade the colostomy stoma with an infant feeding nipple. And do the conventional examination as I showed you with running the barium in part of the way and then introducing air. Next slide. These are usually these tubes are about 26-30 French and they're about the exact same size as um as the colostomy irrigating tubing is given to patients in this hospital. Next line and this is an in vitro picture the patient's introduce this and they always are the one to introduce them because they are familiar with the feel of the irrigating tube entering their colon, introduced this into the descending colon patients holding the nipple against the stomach to tamponade the stomach to prevent leakage and then the barium and air will subsequently be introduced. Next slide. So this is an upright air contrast colostomy enema. Next live and a cubit is view. All the same views are obtained as much as possible. Next line an upright spot film in the splendid lecture tubes in a little farther next line and this is the most dramatic case. We've had to illustrate the value of this technique. This was a patient who had a carcinoma, the rectum and a colostomy performed about four years before and then for the past two years the patient had anemia and this patient had four uh colon examinations in our department for conventional animals. I personally did one of them and called it normal. Uh in retrospective one looks at the system. There does appear to be a vague filling defect, but this was a difficult seek them to palpate many times after colostomy, to seek them will occupy the pelvis and they're difficult to palpate and put pressure on in that region. Next line, the fifth time we examine this patient with their contrast and found this obvious lesion in the second. Um This is the best case. I have to illustrate the value of this technique to this point. Next slide. So in summary double contrast, gastrointestinal examinations are simple to perform. Commercial tools and products are available and any department therefore is capable of performing them. The esophagus stomach duodenum and colon, Both the intact and postoperative colon can be examined with these techniques and I hope I've tried to show you and convince you that these techniques enable diagnostic accuracy not possible with conventional barium studies. I have two more slides. I wish there were more clinicians here to see these slides. But this is a message from our department at least from most of the members of our department to the clinical people. Next line, these are past concepts of radiologists and clinicians have had ugly do bizarre things in the dark, not too bright, couldn't really make it in clinical medicine. That's why they're in radiology. Need a lot of help from clinicians never can make up his mind passive and rich. Next line these are what present concepts and appropriate concept. We are all good looking, highly intelligent. This is the leading medical specialty. We are indispensable to clinicians. Many of us have never even seen a pair of red goggles, let alone warn them were decisive, aggressive but we are struggling financially. Thank you. Yeah. Okay. Yeah.