A CONCISE 
RELATION 
OF THE 
EFFECTS 
OF AN EXTRAORDINARY 
STYPTIC, 
LATELY DISCOVERED: 
IN A 
SERIES of LETTERS 
FROM 
Several Gentlemen of the Faculty, 
And from the Patients, 
TO
BARTH RUSPINI, 
SURGEON-DENTIST, 
TO HIS ROYAL HIGHNESS 
THE PRINCE OF WALES, 
Ne quid falsi dicere audeat; 
Ne quid veri non audeat. 
LONDON: 
PRINTED FOR J. JOHNSON, ST. PAUL'S CHURCH-YARD. 
M.DCC.LXXXIX.




TO THE 
KING. 
SIRE, 
WHEN the Good of Society is the 
Aim of an Individual, and 
when his Exertions to avert some of 
the Evils to which it is subject, meet 
with the Success his Hopes aspired 
to; may he be permitted the Honor 
of laying his Labors at the Feet of 
Majesty? 
A2 The

[iv]
The Arts and Sciences, ever look- 
ing up to the Good, and Great, have 
found the most indulgent Favor from 
your Majesty’s august Protection.— 
The Discovery which I now lay 
before your Majesty, has for its Ten- 
dency, (as I trust the following Pages 
will evince) not only the Mitigation 
of Pain, but even the Preservation 
of Life, 
Your Majesty, ever solicitous for 
the Welfare of those whose Good 
Fortune it is to live under your 
Majesty’s paternal Government, will, 
I humbly hope, be pleased to accept
these

[v]
these Endeavors, to be useful to 
them. 
I am, 
Your Majesty’s 
most faithful, 
and most obliged, 
Subject and Servant, 
BARTHOLOMEW RUSPINI.


INTRODUCTION. 
ACCIDENT, some time since, in 
the pursuit of a very different 
object, put me in possession of a Me- 
dicine, the extraordinary power of 
which is the subject of the following 
letters. 
I have for a short time past, made 
use of it myself, in cases where the 
small blood-vessels in the human 
body have been accidently opened, 
the pain of which it not only imme- 
diately mitigated, but stopped the 
effusion of blood in the most speedy 
and effectual manner. 
A Gentleman who is not more dis- 
tinguished by his exalted station, than 
by

[vii]
by his profound knowledge in philo- 
sophy and medicine, to whom I pre- 
sented a few ounces of the solution, 
found similar proofs of its efficacy in 
two cases. The one, when a servant 
had separated the blood-vessels, at the 
wrist, by a fall, in which he received 
a large wound from the bottom of a 
broken bottle; and the other, from a 
wound made with a razor through 
the external jugular, by a person who 
was insane. 
In this case, which happened some 
distance from London, the effusion 
sprang out with the greatest rapidity, 
but was immediately stopped by a 
pledget dipped in the liquid, and, no 
medical gentlemen arriving ’till seve- 
ral hours after, the wound was then 
found closed, and needed no other 
application. 
Struck

[viii]
Struck with the singular benefit 
such a Styptic would prove to the 
Public, in case it could be brought 
into general use; I applied to a num- 
ber of gentlemen of experience in the 
profession of physic and surgery, to 
make a trial of the medicine, and 
favor me with a fair, and impartial 
account of its effects.—This gave rise 
to a series of experiments on the 
animal world, which I published in 
the first edition of this book, but 
which I shall here, on the score of 
humanity, omit. These experiments 
ended, in proving that I was not de- 
ceived in my hopes of it—they were 
ALL successful. The history of these, 
with the opinions of the operators 
and gentlemen present, may at any 
time be seen at my house. 
The present edition contains the 
Cures performed by it, on the Human 
Body,


[ix]
Body, related either by the patients, 
or the medical gentlemen under whose 
care they were; and should their 
authenticity be doubted, the original 
letters, of which the subsequent are 
true copies, remain in custody for the 
inspection of those, who shall please 
to be incredulous or desirous of seeing 
them. A gentleman, whose universal 
philanthrophy, is as universally es- 
teemed, and whose ability as a Chi- 
rurgeon as much allowed; had the 
misfortune to break his leg, and it 
became necessary to take it off above 
the knee. He assures me, the most 
painful part of the operation was the 
taking up the blood-vessels, of which 
seven required the ligature: That 
the solution here recommended, would 
have precluded the use of the needle, 
and its dire attendant, exquisite pain, 
in five, or six, of them. 
B Repeated


[x]
Repeated observations, in similar 
cases, justify me in affirming, that 
the tourniquet ought to be kept on, 
half an hour or more, as I think 
it always should, and then, very 
gradually loosened, I firmly believe 
in all.
In diseases incident to the sex, this 
Styptic Liquor has proved of infinite 
service; in that Opprobium Medi- 
corum, the Fluor Albus, this injec- 
ted, I have known to cure in a very 
short time. 
That there is nothing noxious in 
its composition, the following cases 
fully exemplify; indeed its use and 
safety as an internal medicine, has 
been productive of the happiest effects 
in hæmorrhages, both of the lungs 
and of the stomach.
A

A 
Concise Relation of the Effects 
OF AN 
EXTRAORDINARY STYPTIC. 
A Letter from J. O. Justamond,
F. R. S. Surgeon to the Westmin- 
ster-Hospital, and Reader of Chi-
rurgical Lectures in London.
Dear Sir, 
IN addition to the account I have already
sent you, of the several experiments I have 
made with your Styptic on the large arteries 
of quadrupeds, I now communicate what I 
have observed of its effects upon the human 
body. The opportunities that have occurred 
of trying it, have been only two: the first 
was in the temporal artery, just above the 
ear, which I was obliged to divide, in re- 
moving a portion of the scalp, previous to the 
B2 application


(12)
application of the trefine for a fracture of the 
scull. The artery in this patient was very 
large, and the stream of blood issuing from it 
very rapid, and of considerable diameter, 
insomuch that I thought it a fair opportunity 
of trying the effect of the Styptic, some of 
which I had in the hospital. I dipped a small 
portion of lint in it, and applying it to the 
divided artery, directed the house-surgeon to 
hold it on slightly with his finger, while I 
proceeded with the operation. In a very few 
minutes he removed his finger, and the 
hæmorrhage was completely stopped; nor 
did it return during the rest of the operation, 
which lasted some time, on account of the 
necessity there was of making perforations 
in the cranium. 
It may, perhaps, be observed, that the 
arteries of the scalp usually stop of them- 
selves, or upon the application of dry lint, 
with a slight pressure. This is true in gene- 
ral; but still every one knows, that, in re- 
moving the scalp previous to the perforation 
of the scull, the size of the artery is so various 
in different persons, that we are sometimes 
obliged to secure them with the needle before 
we can proceed in our operation. As far as 
I can judge, the artery, in this instance, ap- 
peared

(13)
peared to be one of that size which it would 
have been necessary to tie, if your Styptic 
had not been used. Besides, the effect was so 
speedy, in this instance, in stopping a consi- 
derable stream of blood, that I could not but 
attribute it to the power of the liquid; for it 
appeared to me, that no such effect could 
have been brought about in so short a space, 
either by the natural contraction of the artery,
or by pressure, unless it had been continued 
for a longer time. 
The next instance I tried it in was, in an  
amputation below the knee, of the leg of a 
strong muscular man, at the Westminster 
hospital, in the presence of a great number 
of persons. After the removal of the leg, I 
applied dossils of lint, dipped in the liquid, to 
the large arteries, which bled very freely. I 
held them on for the space of five or six 
minutes, after which I began gradually and 
carefully to soften the tourniquet. The 
hæmorrhage appeared evidently to be restrain- 
ed, though not entirely stopped; for the 
blood, which seemed to collect from various 
small vessels of the stump, only fell down in 
drops, and those not very frequent, from the 
most depending part. When the tourniquet 
was quite loose, these drops, for a time, did 
not

(14)
not fall faster or thicker, but seemed, indeed, 
to be less frequent; so that we had some ex- 
pectation of being able to trust entirely to the 
application. But, after waiting some time, as 
this dropping still remained, and the man had 
had a previous mortification in the limb, and 
was therefore unable to bear even a small 
accidental loss of blood so well as a patient 
under other circumstances might have done. 
I thought it prudent not to risque the matter, 
but removed the dossils, and so tied up the 
vessels. Upon taking away the dossils, it was 
a circumstance proper to be remarked, that 
one of the large branches, the anterior tibial 
artery, appeared perfectly closed; and, though 
excited to bleed, by moving the end of it to 
and fro with the finger, yet it did not yield 
any blood. 
I am, dear sir. 
Your very humble servant,
J. Justamond.  
April 5, 1785. 
B. Ruspini, Esq. 
Pall-Mall.

[15]
To B. Ruspini, Esq. Pall-Mall. 
Sir, 
THE Styptic which you sent me is a most
valuable addition to the Materia Medica.
Mr. Glover and I tried it, in an hœmoptoe,
on Mr. Park, of Garlick-Hill, who received 
immediate relief from it. Had the blood, 
which he continually brought up from his 
lungs, proceeded merely from a ruptured ves- 
sel, I firmly believe your Styptic would have 
proved sufficient; but, as there were symp- 
toms of an abcess, attended with a trouble-
some cough, it became necessary to apply 
other means to remove those symptoms, 
which occasioned frequent returns of the 
bleeding. 
From the observation I have made on the 
effects of the Styptic, in various cases, I ap- 
prehend that, where it may be brought into
contact with a wounded or ruptured vessel, 
it will stop the bleeding instantaneously. In 
cases where it can be conveyed by absorption
to the affected part, it will also have an almost 
immediate effect. 
I was desired to visit a patient of Messieurs 
Savage and Taylor, a few weeks ago, seized 
with

[16]
with a most obstinate hæmorrhage of the nose; 
The unfortunate man had lost near four 
quarts of blood, and continued bleeding at 
such a rate, that a few hours must have put 
an end to his existence. Every method had 
been tried in vain. I directed Mr. Taylor to 
apply your Styptic and make the patient 
snuff some of it up his nostrils. It stopt 
the bleeding in an instant, without any re- 
turn since. 
A few days ago it was tried in a case, 
where the mass of the blood was so dissolved 
and broken, that the whole body was covered 
with large purple spots. 
The blood which streamed out of one of 
the patient’s nostrils, was of a blackish red 
colour like the washings of putrid flesh, too 
thin to form a coagulum. 
The man who was the happy object of the 
trial, snuffed some of the Styptic up the affect- 
ed nostril; it stopt the hæmorrhage, pro- 
longed his life for a short time, and, if the 
blood had not been in such a dreadful state, 
might have saved a very valuable life. 
Give me leave to conclude this letter with 
my sincere thanks for the phial you were so
kind 


(17)
kind as to give me for my own use, and with 
observing that no family ought to be without 
so valuable a medicine, in order to have it 
ready at hand against various accidents, 
which might prove fatal for want of imme- 
diate assistance. 
It is perfectly safe as an internal medicine, 
and therefore, in all cases, where, from any 
fall, bruises, contusion, or any unknown 
cause, blood is brought up by spitting or 
vomiting, a few tea-spoonfuls, taken every 
two, three, or four hours, will certainly 
prove effectual. Bloody stools might be re- 
lieved by mixing it with clysters.
All these applications should be made 
under the direction of medical practitioners,
for fear of imprudently stopping some critical 
evacuations. 
I am, Sir, 
Your most obedient 
Humble Servant, 
Francis De Valangin.
Fore-Street, 
July 13, 1785. 
C



(18)
Southgate, Aug. 11, 1785. 
Dear Sir, 
I have seen repeatedly the effects of your 
Styptic upon the division of different arteries 
in quadrupeds, and all experiments have thus 
far succeeded; and I am of opinion, from 
accurate observations, the contractive power 
seems nearly equal in the animal and human 
species; therefore have tried it in the fol- 
lowing cases, which are the only ones out 
of many, worthy your attention. The first
is a poor man at an alehouse having given 
some provocation to a girl who drew beer 
there, and having an empty porter-pot in 
her hand, instantly struck him on the side of 
the head, which divided the temporal artery 
just above the ear. The man who came for 
me said he was bleeding violently, of course
took some of the liquid styptic, which, after 
removing such applications the people of the 
house had procured, all which seemed to have 
no effect, I cleared every thing away, and 
spunged the wound clean; then applied the 
Styptic, embrued with dossils of lint, and in 
four minutes the bleeding ceased. I applied 
some dressings, and confined the whole in 
with a bandage, and it never bled afterwards. 
It


(19)
It may be necessary to mention, the quantity 
of blood lost previous to my attendance was 
at least a quart. The wound seemed to heal 
perfectly sound, as with any other vulnerary. 
Another case that occurred, which I will 
give you a recital of, is of an uterine hæmor- 
rhage, which had continued upon a poor wo- 
man for five months, who had tried a num- 
ber of remedies without effect. The charge 
at times, was so great, that she fainted seve- 
ral times a day: having tried bark and other 
medicines of the styptic, and cold bath, &c. 
ventured upon twenty drops of your Styptic 
internally. Not knowing at that time it had 
been thus taken, she seemed to say she found 
no inconvenience from it, therefore she took 
the above quantity, every four hours, in red 
rose tea; the hæmorrhage ceased, and in six 
or seven days she recovered. If any more of 
these cases occur, I shall think it my duty to 
inform you of the event, let it prove for or 
against, as no medicine has yet been found 
infallible. This has thus far claimed some 
merit, and hope, by pursuing it with atten- 
tion, it may be worthy of greater praise 
amongst the students of Surgery. I remain 
Your most obliged 
Humble Servant,
Wm. Hammond. 
To B. Ruspini, Esq.  
Pall-Mall. 

(20)
Upper Seymour-Street, Aug. 13, 1785. 
To Mr. Ruspini, Pall-Mall. 
Sir, 
I had an opportunity of trying the efficacy 
of your Styptic, last Friday was se’nnight, on 
a maid servant, who had the misfortune to 
cut a piece of the end of her finger quite off, 
which bled very much before I could admi- 
nister the Styptic upon some lint well mois- 
tened with it, in conformity to your direc- 
tions; which, as soon as applied, directly 
stopped the bleeding, and the patient did not 
feel much pain, and that only for a short 
time. As there were no particular directions 
about its being opened, and what should be 
after it was opened to be dressed, as the 
patient was easy, and said she felt no pain, 
I determined to let it remain as it was, till I 
could consult with you about it; and last
Wednesday, which was the fifth day after it 
happened; she held her finger in warm wa- 
ter, till the lint, that was put on with the 
Styptic, came off very easy; and the Styptic 
had not only stopped the bleeding, but ope- 
rated as a healing balsam; and had in a great 
measure healed the wound, which has had 
nothing


(21)
nothing put to it since but some dry lint as 
you directed; and, by looking at it this 
morning, I find it is not at all sore, and is 
almost skinned over; and, although a piece 
of her finger was absolutely cut off, I have 
just reason to think, according to the little 
judgment I have, that she will be able to 
use it, as well as any of her other fingers, 
in a very few days, and that it will quite 
skin over. As this Styptic may be of in- 
finite use to the army and navy, as well 
as the whole community in general; I, who 
as a true lover of my king and country, 
and I flatter myself have the true feelings 
of humanity for all sorts of distresses that 
may affect the human species, should be 
very much wanting, if I did not give you 
all the encouragement I possibly could, 
and particularly as you do not wish for 
a patent, and scorn to ask for a premium, 
and so liberal as to declare you will admini- 
ster it to the poor gratis at all times: You 
therefore will ever find me one that will 
be happy, whenever I have it in my power 
to countenance you, or to be of any ser- 
vice to you, or any one that merits from 
the public the esteem I think you do; and 
shall be glad to find you meet with every 
encourage-


(22)
encouragement equal to your deserts, which 
is the sincere wish of 
Your friend and humble servant,
Ferrers. 
Edmonton, Aug. 17, 1785.
Dear Sir, 
I should esteem myself unworthy of your 
future friendship, were I to omit any oppor- 
tunity of informing you of the singular effi- 
cacy of your Styptic, in a case which I have 
the honour of communicating. 
I was sent for, to attend a poor man, who 
had met with an accident as he was reaping 
of corn. Having cut his hand with a fickle, 
the wound, passing through part of the 
Abductor Pollicis, had divided a branch of 
the radial artery. The loss of blood had 
made him very faint, so that I immediately 
soaked some dossils of lint in the Styptic 
Solution, and applied them to the orifice of 
the divided vessels. I then secured the dres- 
sings by compress and bandage. The wound
was

(23)
was thus left till the third day, when I 
found it in a healing state with a good sup- 
puration; and in a fortnight it was perfectly 
well. 
Whatever opportunity may hereafter occur 
of trying this valuable Styptic, you may be 
assured shall not be neglected; you will re- 
ceive the earliest and most faithful account 
of it from, 
Dear Sir, 
Your most obedient,
and most humble Servant, 
Thos. Hammond. 
To B. Ruspini, Esq. 
Pall-Mall. 
A

(24)
A Second Letter to Mr. Ruspini, on the 
Use and Advantages of his Styptic, from 
J. O. Justamond, F. R. S. Surgeon to 
the Westminster-Hospital, and Reader of 
Chirurgical Lectures in London. 
Monday, September 5, 1785.
Dear Sir, 
On Saturday last I had another opportu- 
nity of trying your Styptic at the Westminster 
Hospital. Having performed an amputation 
below knee, and secured the great vessels by 
ligature, there were two or three branches, 
which, as it often happens, bled so freely,
that, unless I had found some means to stop 
them, I should have been obliged also to tie. 
I dipped some dossils of lint in your Styptic, 
and, applying them to the bleeding vessels, 
held them on for the space of a minute only, 
when the hæmorrhage was completely 
stopped, and did not return. 
I am, dear Sir, 
Your’s sincerely,
J. O. JUSTAMOND. 

(25)
A Third Letter to Mr. Ruspini, on the 
Use and Advantages of His Styptic, from 
J. O. Justamond, F. R. S. Surgeon to 
the Westminster-Hospital, and Reader of
Chirurgical Lectures in London. 
Queen Ann Street, September 8, 1785. 
Dear Sir, 
IN the conversations we have had toge- 
ther, on the subject of your Styptic, you 
have often mentioned that many persons have 
objected to it on the ground of its doing no- 
thing more than many other styptics which 
the faculty are in possession of, and conse- 
quently there was no reason for giving it any 
preference. At the same time you have fre- 
quently urged me to give you my opinion of 
this in writing, which I do with great readi- 
ness from the observations, which the fre- 
quent trials I have made with it myself, and 
those which I have seen made by others, have 
suggested to me. 
In order to draw a comparison between 
your Styptic and others, it will be necessary to 
institute a short inquiry into the nature and 
effects of the styptics that are known and in 
common use. 
D Most


(26)
Most of the liquors, or tinctures, employed
for the purpose of stopping hæmorrhages, are 
either absolutely caustic, or possess a greater 
or less degree of pungency, which occasions 
considerable pain in the application. The 
oil of turpentine, one of the most effectual, 
and, at the same, not the most severe, is not 
exempt from this defect, of which I have 
lately seen a remarkable instance. Having 
performed the operation for a natural phy- 
mosis, the patient, about two hours after I 
left him, was suddenly seized with a most
violent hæmorrhage, of which there was no 
sign at the time of the operation. Being gone 
about my business, and at some distance from 
home, I could not get information of this 
accident till three or four hours after it hap- 
pened. In the mean while, the hæmorrhage 
continued with great violence, so as to alarm 
the patient, and make him very faint, he 
was under the necessity of sending for assist- 
ance in the neighbourhood. A gentleman, 
who had been pupil to me, being called in, 
readily stopped the bleeding, by dressing the 
wound with lint dipped in oil of turpentine. 
When I called about three o’clock, my pa- 
tient (a young man, who bore pain very well) 
complained of his having been in the most
extreme

(27)
extreme agony and torture for three hours 
after the application; saying, that he had 
sufFered infinitely more than from the opera- 
tion. This pain had only begun to subside 
about half an hour before I came; and when 
I dressed him, I was not in the least surprised 
at it, for the skin of the prepuce wherever 
this essential oil had touched it, was much 
inflamed and full of blisters. The inference 
is clear; had your Styptic been used, I am 
convinced it would have restrained the bleed- 
ing as effectually; and the natural anguish of 
the wound, far from being increased, would 
rather have been relieved by it, as I have 
often happily experienced. 
The chief solid substances, recommended 
for stopping hæmorrhages, are, the agaric of 
the oak, dried sponge, Faynard’s powder, as 
it is called, and the Lycoperdon, or puff-ball. 
The two former are of the same nature, 
and though more effectual than any of the 
known styptics, except the caustic or actual 
cautery, yet I have found a very material 
inconvenience attending the use of them: 
this is, that they stick so firmly to the ves- 
sels, and for so long a time, that they can- 
not be removed without much pain, or 
D2 without

(28)
without endangering a fresh hæmorrhage.
In one instance of an amputation at the meta- 
tarsus, where I had used the sponge, I re- 
member, that all the rest of the wound was 
healed, except the spot where the sponge lay: 
this alone obstructed the healing for some 
time; and I was at length obliged to cut it 
off, little by little, with the utmost caution. 
Faynard’s powder, and the Lycoperdon, I 
have tried frequently, and am satisfied, al- 
though they have some astringent power, that 
their efficacy is not equal to that of your 
Styptic. 
Another objection, you tell me, made to 
your Styptic, is, that it cannot be trusted to, 
in the larger arteries, after amputation. But, 
the persons, who raise this objection, should 
recollect, that we do not want it for this pur- 
pose. Let a styptic be ever so effectual, I 
should scarce think a man justified in trusting 
to it in these instances, unless he staid himself 
with the patient, night and day, for three
days after. So, when I tried it in an ampu- 
tation, it was merely to observe and to give 
an account of its effects; for I declared pre-
viously, whatever the result might be, that I 
had determined not to trust it. Besides, the 
present

(29)
present improved mode of amputating, pre-
cludes us from using any application to the 
stump, if it can possibly be avoided. Farther, 
the large trunks of arteries in any amputation 
are never more than three; notwithstanding 
which, it frequently happens, either from the 
state of the patient's health, or of his blood, 
or from some other circumstance, that we are 
under the necessity of repeating the ligature 
upon several of the collateral branches; as 
would have been the case, in the instance I 
sent you an account of lately, had I not used 
your Styptic. Now, a styptic, which, after 
the large arteries are secured, prevents the 
painful repetition of the ligature upon the 
smaller branches, and stops the bleeding from 
them, without causing the least pain, and 
without any subsequent inconvenience, is cer- 
tainly a very valuable acquisition to mankind, 
as well as to our art. Such I take your 
Styptic to be. 
Moreover, there are cases of hæmorrhage, 
where the ligature cannot be applied. Such 
was a violent bleeding I once saw from the 
corpus cavernosum penis, in consequence of 
its being corroded by a chancre. Neither oil 
of turpentine, nor any thing would do here,
except 

(30)
except the lunar caustic, which was not ap- 
plied without much pain. From what I have 
seen of your Styptic, I am fully of opinion, 
that it would have answered the purpose in 
this case. 
In the operation of Lithotomy, and in that 
for the sistula in ano, there are frequently large 
vessels divided, which are not within reach 
of the ligature, and where the hæmorrhage 
sometimes proved fatal. A styptic which 
will stop this hæmorrhage, without giving 
pain, or irritating the parts, which in these 
operations must be particularly avoided, is 
therefore a desideratum in Surgery. 
In nasal hæmorrhages, and in violent, and 
sometimes unrestrainable bleedings, after the 
extraction of the polypus, a powerful liquid 
Styptic, that shall act without giving pain, or 
causing irritation, is also a very valuable ac-
quisition. 
It appears likewise from some accounts 
sent to you from good authority, that your 
liquid has been applied with safety and suc- 
cess, as an inward remedy, in some internal 
hæmorrhages of a very alarming nature.—
There is no occasion to dwell on its pre-emi-
nence


(31)
nence to other styptics in this respect. It is 
scarce possible to determine how extensive its 
utility may prove in this view.—It will be 
proper to try it in uterine hæmorrhages, 
hæmoptoes, dysenteries, and internal bleed- 
ings of any part from contusions. How it 
produces its effect in these cases, is not easily 
ascertained; but facts admit of no dispute. 
Upon the whole then it may fairly be con- 
cluded, even admitting, that your Styptic 
cannot be trusted to in the larger trunks of 
arteries, that it is still very extensively useful, 
and preferable to any styptic previously em- 
ployed; because it gives no pain; because it 
is free from the inconveniences attending upon 
other styptics; because it appears to be more 
powerful than most of them; and because it 
is so innocent, that it may be administered with 
safety as an internal medicine. 
I hope farther testimonies will confirm its 
numerous advantages; and am, 
Dear Sir, 
Your faithful humble servant, 
J. O. Justamond.
B. Ruspini, Esq. 
Pall-Mall. 

(32)
Fore Street, Sept. 13, 1785. 
DEAR SIR, 
SINCE I had the pleasure of communi- 
cating to you the several cases in which your 
valuable Styptic was of service, a most re- 
markable instance of its power has almost 
impressed its character as an infallible Styptic 
in my mind. 
* Mr. Samuel Gorst, Chief Mate of the 
Goddart, East-Indiaman, in consequence of a 
strain, having burst a large blood-vessel in
the stomach, was taken with an incessant 
vomiting of blood: the quantity, in less than 
half an hour exceeded a gallon. As no time 
was to be lost, having half a phial of your 
Styptic left, I ordered one table spoonful to 
be taken immediately, after which he brought 
up one pint of coagulated blood; the Styptic 
was repeated, and the bleeding stopped; and, 
in order to prevent a return, and to restore 
* His brother yesterday (May 13, 1787) told Mr. Ruspini, 
that recent letters from India, inform him, that he has had no 
return of his hæmorrhage, and that he continues in the most 
perfect health, and is soon expected home. 
the

(33)
the crasis of the blood, which appeared to be 
in a dissolved state, I prescribed a milk diet, 
and other proper medicines. 
I am, 
Dear Sir,
Your most obedient humble servant, 
Francis De Valangin. 
B. Ruspini, Esq. 
Pall-Mall. 
Southgate, December 3, 1785. 
Dear Sir, 
THE following case occurred to me about 
two months ago: nothing but the hurry of 
business should have prevented me from 
communicating it to you much sooner. 
A poor woman living at Winchmore- 
Hill, at the distance of about two miles, 
being advised to shew me a very deep ulcer 
which she had on the interior part of her 
left leg, came to Southgate for that pur-  
pose in a cart; and, in stepping out of 
E it


(34)
it, she ruptured, in the centre of the ulcer, 
a branch of the interior tibial artery, if not the 
trunk itself, for the stream of blood was as large 
as any I had ever seen in amputation. When 
I was called down to the woman, I found her 
fainting and bleeding very fast. I then com- 
pressed the bleeding orifice with my finger, 
while I desired twenty drops of your Liquid 
Styptic to be dropped on a piece of lint, 
which I applied, holding it on with my 
finger. In two minutes the bleeding was 
entirely stopped; and, in about half an hour, 
the woman having recovered from her faint- 
ing, returned home with the same dossil of 
lint secured by bandages. The motion of 
the cart had no effect in renewing the 
hæmorrhage, which never returned. The 
quantity of blood she lost in my house 
amounted to five pints, beside what was lost 
at the gate, and in bringing her from the 
cart, which stood at the distance of fifteen 
yards. The ulcer healed in about three 
weeks after. I am, 
With the greatest respect and esteem, 
Dear Sir, Yours, &c. 
Wm. Hammond.
To B. Ruspini, Esq.
Pall-Mall. 
A

(35)
A Copy of a Letter from Mr. Brice, Sur- 
geon, to B. Ruspini, Esq. 
Sir, 
AT different periods for years past, I have 
been troubled with a bleeding at the nose; 
a hæmorrhage from that part, always distres- 
sing, was the more so to me, as it generally 
came on when I sat at table. I have used 
various applications, but to little, or no 
effect. 
A few weeks since, in company with Mr. 
Boys, a medical gentleman of reputation in 
Berners-Street, I related to him my case; 
he desired, when the hæmorrhage returned, I 
would have immediate recourse to Mr. 
Ruspini's Styptic Water. 
The very same evening, as I was at supper 
with the above gentleman, the part bled 
again with its accustomed violence. I im- 
mediately introduced into the nostril, a small 
dossil of lint imbrued in the Styptic, and, to 
my great surprise, the blood from that time 
instantly ceased to flow. 
Some time after, at breakfast in the hos- 
pital where I reside, the vessels bled a second 
E2 time,

(36)
time, the blood gushed out with amazing 
rapidity; retiring to my room, I laid myself 
back on the bed, continually applying wet 
cloths to the external parts, till at last I 
thought I had fully accomplished my design,
and stopt the bleeding; but, on getting up, 
I found all my attempts frustrated, as the 
blood flowed with additional velocity. I im- 
mediately sent for my friend Mr. Boys, whose 
avocations not permitting his personal atten- 
dance, he returned me by the servant, a bot- 
tle of your Styptic, with proper directions. 
I applied it as ordered, and it had the same
sudden, and good effect as before. Near 
three months are elapsed since that time, 
and I have had no return. 
In justice then to you, for the great be- 
nefit I have experienced from its use, I 
send you this letter, which, if you please, 
may be communicated to the public for 
their good. 
I am, Sir, 
Your very obliged Servant, 
Henry Smith Brice. 
Store-street, Bedford-Square, 
December 7, 1785.
Mr. Brice has had no return of the Bleeding since. 


(37) 
Dear Sir, 
I KNOW not if any case similar to the 
one I am about to relate, has occured to you 
or your friends, where your Styptic Water 
proved a remedy; indeed, whatever your 
private opinion may be, I do not know that 
you have once hinted to the public its posses- 
sing a property, which as far as one instance 
can go, it apparently does. 
I was induced to apply the Styptic in this 
case, from a consideration, that, if it had 
the power to stop the blood in vessels of a 
large diameter, it must evidently produce the 
same effect in smaller; and, though the pre- 
sent case is not so similar, that a postula- 
tum can be drawn, yet the bloody pus in the 
pimples, and the many small ramificatory 
branches of the vessels which produce 
it, seemed to point out the Styptic as a 
remedy. 
In fact, the pus, or sanies, itself, appear 
to me, in these eruptions, to be nothing 
more than the eroded extremities of the cuti- 
cular vessels letting out their contents; and 
these, confined by the cuticle, are converted 
into


(38)
into matter, by a process I do not pretend to 
define, but the effect of which, is demon- 
strated daily by the unhappy experience of 
those, whose misfortune it is to be in a simi- 
lar situation with the subject of this letter. 
I am well aware that other styptics, here- 
tofore recommended by their respective advo- 
cates on the same principle, may have pro- 
duced the same effect; but, when we consider 
that the major part of them act only as strong 
astringents, however unnecessary to the 
medical reader, ’tis of the last consequence 
to the sufferer, to inform him how detrimen- 
tal it may be to apply an astringent medicine 
to an eruption; that very eruption being an 
effort of nature to get rid of a matter offen-
sive to itself. 
Your Styptic Water having (in the usual 
acceptation of the word) no astringent pro- 
perty, at least I know of none it has, is free 
therefore from any objections of this kind; 
how it acts I will not pretend to say: I am 
not fond of theory, or indeed capable of 
accounting for the effects of medicines; I 
know that certain drugs have certain opera- 
tions evident to our senses: your Styptic 
Liquid

(39)
Liquid, in the following case effected a 
cure. 
A young lady between 17 and 18 years of 
age, was placed under my care for a tumour 
in her left breast, caused by the blow of a 
school-fellow, and which had resisted the 
usual mode of domestic treatment; had also, 
what is generally called, a pimpled face; I 
ordered what I thought proper for the swell- 
ing in her breast, which in a month was so
small, as scarcely to be felt. 
The medicines, used for that purpose, did 
no service to her face; indeed, I did not 
expect they would, as I think in this case 
there could be no analogy between the tumor 
and eruptions; but, as she was extremely 
unhappy, and much distressed at her appear- 
ance, and as the pimples often bled when she 
washed, or wiped her face, I prescribed your 
Styptic Water: she wetted her face with it 
twice a day with a linen rag, and, by conti- 
nuing so to do six weeks, she was restored to 
a very fine complexion. 
I remain, Dear Sir, 
Your most faithful humble servant,
John Boys.
Berners-street, 
Dec. 7, 1785. 
To B. Ruspini, Esq. Pall-Mall. 


(40)
Gravesend, February 15, 1786. 
My Dear Sir, 
I Do not recollect one instance in the ac-
count of your Styptic, where its application 
was more strongly marked with success, than 
in the following case. 
John Lambert, a shipwright, of North- 
Fleet, in Kent, received a wound on the su- 
perior part of the tibia, which penetrated to 
the bone, and opened a branch of the tibialis 
antica: after many applications had been un- 
successfully tried to stop the bleeding, and 
full five hours after the accident happened, I 
was sent for. 
Having in vain endeavoured to restrain the 
hæmorrhage by the usual means, I thought 
the case a fair one for the trial of your Styptic. 
Accordingly, a dossil of lint, wet with a few 
drops of it, was lightly pressed on the bleed-
ing artery, about half a minute: on removing 
my finger, I was much pleased to find the 
blood intirely stopped: afterwards an easy 
bandage

(41)
bandage kept on the lint, and in a short 
time, without any other assistance, the man 
was well. 
I remain, 
Your most humble Servant, 
Charles Kite.
B. Ruspini, Esq. 
Pall-Mall. 
Gravesend, March 1, 1786. 
Dear Sir, 
IN addition to the case lately sent, I now 
transmit you, an account of the effects of 
your Styptic, on two, or three cases, which 
have occured to me since that time; and if 
you think them worthy of attention, they 
are very much at your service. 
I am,
Dear Sir, 
Your very humble servant, 
Charles Kite.
F 

(42)
JOHN GROVER, a tide-waiter, belong- 
ing to the customs, applied for my advice, 
concerning a tumor in his mouth. On exa- 
mination, I found a large excrescence, arising 
from the exterior gums of the left side of the 
lower jaw: its base comprehended the three 
middle dentes molares, but its body extended 
the length of the five, and it was three parts 
of an inch thick. It had been ten years ar- 
riving at this size, and during the last two, 
had, at times, been the source of very great 
distress. 
Extirpation was recommended, and at 
length agreed to. The tumor was carefully, 
though with some difficulty, disunited from 
the gums; and proved of a very firm cartila- 
ginous consistence, interspersed with a boney 
substance. In the operation, the artery 
which nourished the tumour, was divided, 
and threw out its contents in a continued 
stream: I mentioned this to my friend Dr. 
Buys, who happened to be with me, as a fair 
case to make trial of your Styptic in, and he 
coincided in my opinion. The liquid was 
therefore applied according to the directions, 
the bleeding immediately stopped, and the 
wound


(43)
wound healed, without further assist- 
ance. 
—STUBBS, a lad about fifteen years 
old, in corking a bottle improperly, broke 
it, and cut his hand: a violent and profuse 
hæmorrhage ensued, which, by lint, flour, 
and tight bandage, was several times mode-
rated, but never entirely stopped. At the 
expiration of three hours, the bleeding re- 
turned as violently as at first: the dressings 
were then removed, and the lad declares, the 
blood flew upwards of a yard from him. I 
was now sent for, and my assistant attended 
in my absence; he applied some lint, moisten- 
ed with the Styptic, and the bleeding instantly 
ceased. 
The wound was inflicted on that part of 
the hand where the thumb forms the joint 
with the bones of the wrist, and the radial 
artery was wounded about an inch below the 
spot where we examine the pulse. It is 
usual, I believe, for the artery near this place, 
to give off only a branch to the abductor 
F2 pollicis,


(44)
pollicis, but it often happens, (and it is so 
in a preparation I have now before me) that 
instead merely of giving off a branch, it divides 
into two equal portions: from the quantity 
of blood that was lost; the large stream it 
poured out in, and the length of time the 
bleeding continued, notwithstanding the 
means that were used, I have little doubt but 
that this was one of those cases; however, 
whether it was, or was not, the fact is clear, 
that an artery of some considerable size was 
wounded, and that the bleeding was stopped 
by the Styptic, after compression had been 
used in vain. 
WILLIAM LOWE, a hearty strong 
young fellow, about seventeen years of age, 
by a fall on board a ship, received two wounds 
on the head, which penetrated to the bone. 
Symptoms, indicating a compressed state of 
the brain, soon came on; and when bleed- 
ings, purgatives, and sudorifics, had in vain 
been had recourse to, I was consulted. There 
was no time to be lost in applying the tre-
phine,

(45)
phine, and a piece of the skull was therefore 
instantly removed. One opening not being 
sufficient, it was necessary to enlarge the
wound in the scalp, to make room for ano- 
ther: in doing of which, one artery in parti- 
cular was divided, which it was necessary to 
secure immediately, as the patient was evi- 
dently much too low, to bear a very 
trifling additional loss of blood. I thought 
this a very unfair case to use the Styptic in, 
as there was no opportunity of confining it 
to the part even for a minute, and therefore 
intended to use the ligature; but as I wished 
to observe the astringent effects of the liquid, 
independent of compression, I determined to 
make the trial, and if it did not succeed im- 
mediately, to take the artery up with the 
needle. A piece of lint well moistened with 
the Styptic, was then laid on the part, and 
being retained about half a minute, the effu- 
sion almost immediately ceased; nor did it 
return, although the lint was soon removed, 
and the part frequently, and severely rubbed, 
by the violent exertions of the patient. 
C. K 
To B. Ruspini, Esq. Pall-Mall.


(46)
Copy of a Letter from Dr. Young, 
To B. Ruspini, Esq. 
East Grinstead, Sussex, April 16, 1786. 
Dear Sir, 
AS you was so very obliging as to pre- 
sent me with a bottle of your Styptic, I 
should esteem myself guilty of the greatest 
ingratitude if I did not communicate to you 
the very great efficacy of it, in almost im- 
mediately stopping a very violent internal 
hæmorrhage.—The case was this: 
A Gentleman, a few miles from East
Grinstead, while in bed and almost asleep, 
was suddenly roused by the bursting of a 
considerable blood-vessel in the gullet, the 
report of which, his lady told me, was 
almost as loud, she thought, as that of the 
going off of a pistol; in consequence of 
which, a large hand bason which stood near 
him, was almost instantly filled with blood, 
on which they immediately sent for me; but 
being at the distance of six miles, it was a 
considerable time before I could possibly get 
there, when from information, and from 
what I saw, he could not have vomited less,
if 

(47)
if so little, as six quarts of blood, and was 
still vomiting up more. I immediately 
gave him two tea spoon-fulls of your Styptic 
which kept down about ten minutes, when 
he vomited up some more blood (which was 
altered in colour to that of chocolate) with 
some coagula. I instantly gave him two 
tea-spoonfuls more, which he retained for 
upwards of twenty minutes, and when he 
vomited again, no more blood appeared, 
exclusive of a few filaments of the blood, 
which had lodged in the stomach, and 
though he vomited, I believe not less than 
twenty times, in the space of six or seven 
hours afterwards, not one drop more of 
blood appeared, excepting those filaments 
I before mentioned: neither has he brought 
up any to this day which is now just a fort- 
night ago, and he is as well, nay, he tells 
me that he is much better than he has been 
for this year past, exclusive of weakness. I 
think, Sir, for the sake of humanity, the ex- 
traordinary effects of your Styptic cannot be 
made too public, and you are at liberty to do 
with this as you may think proper. The 
gentleman, who is the subject of the above, 
is David Knox, Esq; Crawley Down, near 
East

(48)
East Grinstead, who will, if required, attest 
to the above relation. 
I am, with great respect, 
Dear Sir, 
Your very obliged, 
Humble servant, 
Thomas Young. 
P. S. I Shall be obliged if you will send me by 
the Lewis coach, a large, and a small 
bottle of your Styptic, and I will remit 
you the money the first opportunity.
The Case of Mr. Davis, Optician, 
In Macclesfield-street, Soho, 1786. 
—DAVIS, aged about forty years, was 
seized on the 2d of March, with a violent 
hæmorrhage at the nose, which baffling all 
endeavours to suppress, he applied to the 
late Dr. Robert Bromfield, and to Mr. 
William


(49)
William Lucas, who used every means pro- 
fessional knowledge suggested, to give him 
relief, but without effect; for though the 
bleeding was sometimes a little checked by 
their application, it still continued in a great 
degree, and soon returned with accumulated 
violence. In this condition he languished 
three days, during which time, it was com- 
puted he lost at least, upon the nicest calcu- 
lation, seven quarts (i. e. fourteen pounds) of 
blood, which in this state (contrary to the 
opinion of the gentlemen who attended him, 
and who were well acquainted in what man- 
ner he had conducted himself for some years 
past), was most exceedingly sizy. There 
were consequently very small hopes of reco- 
very; every possible means having been tried 
without effect, to stop the hæmorrhage, he 
was induced to make a trial of Mr. Ruspini’s 
Styptic, a small quantity of which being 
poured on dossils of lint, was introduced up 
the nostrils. 
It was the opinion of the faculty, that the 
blood flowed from the small branches of the 
artery, notwithstanding which the patient 
speedily found that the Styptic decreased the 
complaint, diffusing a glow over the side of 
G the

(50)
the face and head affected; but the most
essential service he derived, was by injecting 
a small quantity at a time with a syringe up 
the nose. 
After repeated applications of the medicine, 
the hæmorrhage entirely ceased; and con- 
trary to the expectation of every one (who 
saw him in his illness, and witnessed his ex- 
hausted, deplorable situation) Mr. Davis 
recovered, and thinks it his duty, both to 
Mr. Ruspini and the public, to make this 
voluntary declaration, respecting the astonish- 
ing effects of an invaluable medicine, to which 
he owes his existence. 
Any person wishing to have further satis- 
faction upon this subject, may see Mr. Davis, 
at his house in Macclesfield-street, Soho, 
who is ready, if necessary, to certify the same 
upon oath. The facts can also be corrobo- 
rated by several respectable characters in the 
neighbourhood; and Mr. Lucas, the medi- 
cal practitioner abovementioned, has candidly 
signed his name to this case, as a further proof 
of its authenticity. 
W. Lucas. 

(51)
Among many other Cases of Nasal Hæmorr- 
hage, in which the Styptic Solution was 
used with the happiest Effects; the following 
is deemed of too important a Nature to be 
omitted in this Relation. 
ON TUESDAY, the second of May 1786, 
ONE OF THE FIRST CHARACTERS 
in these kingdoms, who is not more distin- 
guished by the greatness of his rank, than 
for the amiableness and liberality of his man- 
ners, on his return from the country, was 
suddenly seized with a violent nasal hæmor- 
rhage, which for some time greatly alarmed 
his attendants; but on a small quantity of 
the Solution being applied, as usual, on lint, 
to the part affected, the bleeding was effec- 
tually stopped; and we have the best authority 
to declare, that no return of the complaint 
afterwards took place.
G2 Sir,

(52)
Sir, 
I MAKE one amongst the many who 
have experienced the surprising efficacy of 
your excellent Styptic; and, though perhaps 
last, in point of time, in offering you my 
acknowledgment; I am by no means least in 
gratitude. 
About four years ago, I was attacked with 
a spitting of blood, which became in a man- 
ner periodical, and seldom failed to return 
once and sometimes twice a year. I went 
through a regular course of bleeding and 
Starving; the maxim of Moliere's Mock- 
doctor, Bleedere & rebleedere, was put in full 
force, and had no other effect than stopping 
the hæmorrhage from want of blood, and 
greatly impairing my constitution. 
Tired of these sanguineous operations, more 
so of the low diet I was sentenced to, and 
above all, fearing least I should waste away 
secundum artem; I resolved, on your first 
publishing the liquid Styptic, to try what 
relief I could get from it. The consequences 
have been such, that, instead of lasting a fort- 
night as usual, the fits, which I have had 
since, were over in two or three days; the 
period

(53)
period of their return became less frequent;
and the last I have been afflicted with, did 
not last above three hours, during which I 
did not throw up a tea-cup-full of blood: I 
am at present perfectly recovered; nor do I 
dread a return, being certain of an effectual 
antidote in the use of your inestimable me- 
dicine. 
I am, with the truest esteem and most sin- 
cere gratitude. 
Sir, 
Your obliged humble Servant, 
Parkyns Mac Mahon. 
Hay-Market, 
August 29, 1786. 
To B. Ruspini, Esq. Pall-Mall. 
My Dear Sir, 
IN the evening I was sent for to a poor 
woman in George-street, Queen-Ann-Street, 
East, who in consequence of violent exer- 
tion, laboured under a profuse hæmorrhage 
per Vaginam. 
I pre-

(54)
I prescribed what is usual, and ordered her 
not to leave her bed on any account; she 
neglected my advice, and in the morning 
early, I was again called; when the discharge 
had ran through the bed and a quantity of 
blood laid underneath. 
I sent home for your Styptic, and with a 
Syringe injected half an ounce; in ten mi- 
nutes as much more. The flooding gradu- 
ally decreased, and at night had altogether 
ceased. 
I am inclined to think a smaller quantity 
of the Styptic might have effected the pur-
pose, had it been used in the manner below 
described *; since mixing with the refluent 
blood, it must be somewhat weakened. 
I am, 
My Dear Sir, 
Your’s very sincerely, 
J. Boys.
Berners-Street.  
B. Ruspini, Esq. 
Pall-Mall. 
* Inject a female Syringe full of equal parts of cold Water 
and Vinegar, and immediately after, another of the Styptic; 
in ten minutes repeat the injection if there be occasion. 
Southgate,

(55)
Southgate, October 7, 1786. 
Dear Sir, 
THE two following cases have occurred 
since I addressed you last; in which your 
Styptic has succeeded. The first was in the 
month of June last:—An inhabitant of 
Southgate, a lady aged seventy or upwards, 
was taken with a violent fit of coughing after 
dinner, very sick at stomach, and was some 
time before she could discharge the load she 
felt; when upon taking a pint of warm water, 
had the desired effect, and vomited a large 
quantity of blood, and continued to discharge 
the same every time the cough returned. She 
had no cough before the evening she was in 
this alarming state; therefore I conclude the 
cough spasmodic, to throw off the blood that 
oppressed her. I was from home, and was 
sent for to her; I took some of the Styptic 
with me, and gave her a desert spoonful in 
water; the cough did not return so frequent, 
and though she raised blood often, in two 
hours time it diminished greatly. 
She was low from the lost of blood; and 
for fear she should not have the Styptic regu-
larly given, I mixed up in the form of 
draughts


(56)
draughts the same quantity of Styptic as at
first prescribed to an ounce or more of simple 
cinnamon water, and ordered her to take one 
every four hours. The next morning at 
nine o’clock I saw her; and upon enquiry 
she told me, she had discharged nothing the 
least tinged with blood, after three o’clock 
that morning; her pulse was then about se- 
venty; no sickness, and the cough had in- 
tirely left her. I visited her only twice after; 
she has had no symptoms of that complaint 
since; and she has travelled a very long 
journey, and returned to Southgate. The 
name of the lady is Gaywood. 
October the 1st. Mrs. Lucas in this 
neighbourhood, from what cause I know not,
but some years ago was troubled with fits. 
She was suddenly seized with a violent hæ- 
morrhage from the nose; so much as to pro- 
duce faintings; those about her had tried 
every method they knew of, but the bleed- 
ing continued as violent as ever. I went, and 
applied the Styptic upon lint up the right 
nostril; the left then began bleeding, and I 
did the same to it: and in two minutes, it 
intirely stopped. She, two days after, had a 
slight return; she made use of the same ap- 
plication

(57)
plication, and it ceased as before; has had 
no return since. These two cases, I think, 
tend to corroborate the success of this disco- 
very, so useful to mankind, in all the trials 
I have hitherto made of it; and I doubt not 
in time it will become a valuable acquisition 
to the practice of surgery in general. 
I remain, Dear Sir, 
Your devoted obedient Servant, 
W. Hammond. 
B. Ruspini, Esq. 
Pall-Mall. 
Sir, 
ON Tuesday last, I received a signal proof 
of the great efficacy of your Styptic; the
case was as follows: 
About ten o’clock on the above evening, 
Mr. Smith, victualler, opposite Justice Hall 
in the Old Bailey, in throwing up the sash, 
accidentally broke the glass, and divided the 
blood-vessels at his wrist. The superficial 
H veins


(58)
veins over the carpal ligament, were quite 
cut through, and the radial artery punctured, 
so that the blood started out by jerks with 
great violence. In this alarming state, seve- 
ral applications were made use of, to restrain 
the hæmorrhage, without effect. Some time 
after this, on hearing Mr. Smith’s distressed 
situation, I called upon him, and saw the 
blood plentifully flowing from the above 
orifices; upon which, I applied a pledgit 
dipt in a small quantity of your Styptic Solu- 
tion, when the bleeding instantly stopt, 
returned no more, and no bad consequences 
ensued from this disagreeable accident. 
I am, 
Sir, 
Your humble servant, 
R. G. Pearce. 
Old Bailey, 
Aug. 24, 1786. 
To B. Ruspini, Esq. Surgeon Dentist to 
H. R. H. the Prince of Wales.
Sir,

(59)
Sir, 
HAVING been witness to the best effects
from the use of your Styptic in internal bleed- 
ings (particularly in the case of Mr. Park, of 
Garlick-Hill) I gave it to a young Lady, Miss 
S—, of Chester, for a disorder, which 
was supposed to arise from some ruptured 
blood-vessels in the stomach. The lady, 
who was about twenty-two years old, had 
for upwards of eight months, thrown up, 
generally twice a week, from three to six 
ounces of blood, which reduced her to a very 
low state. 
When I saw her for the first time, the 
13th of August last, she had by the advice of 
her physician taken for about ten days, small 
quantities of the Tincturâ Saturnina, which 
at first seemed to relieve her, at length pro- 
duced violent vomitings, which were ac- 
companied with several ounces of florid blood, 
and seemed to convulse her in a very dange- 
rous manner. In this situation I gave her a 
tea-spoonful of your Solution every half hour 
for three hours, in which period, the 
hæmorrhage by degrees was lessened, and 
then intirely stopt. The same evening she
H2 slept 

(60)
slept well, and the next day took a tea-spoon- 
ful of the Styptic only every four hours. 
She continued to persevere in the use of 
the medicine, till the 24th of September; 
and at the time I was writing this, has had 
no return of her complaint, though she has 
frequently rode on horseback, which she was 
not able to do for several months before. 
Her appetite and spirits are exceeding good, 
and she is at present free from any kind of 
complaint. 
I cannot upon this occasion avoid mention- 
ing, a recent case of internal hæmorrhage 
which ended fatally; it is that of Mr. John 
Berbeck, late of the ship, President, belong- 
ing to Mr. Brocklebank, Merchant, at 
Wigton, in Cheshire. This young man 
returned from sea, in the summer of 1785, 
with a rupture of a blood-vessel in the sto- 
mach, which brought on a dropsy, for which 
he was tapped seven or eight times. 
The last operation seemed to relieve him 
exceedingly; but some time after, on riding 
on horse-back, he was again attacked with a 
violent bleeding from the stomach, which 
continued

(61)
continued till the next day, when it termina- 
ted his existence. 
I only mention the case of this unfortunate 
youth, as from the success your medicine, to 
my knowledge, has had in a similar case; I 
think it would certainly have prevented his 
dissolution. 
I am, Sir, with great respect, 
Your most obedient servant, 
SAMUEL COUGH.
Bath, 
October 3, 1786. 
To B. Ruspini, Esq; Surgeon Dentist to 
H. R. H. the Prince of Wales. 
October 17th, 1786. 
Royal Hospital at Haslar, near Gosport. 
Sir, 
HAVING used almost one small bottle of 
your Styptic with such success as intirely to 
remove my suspicions that the ligature must 
continue


(62)
continue to be the only styptic a surgeon 
could rely on, I take the liberty to transmit 
to you an account of the cases in which I have 
tried it. 
CASE I. 
JAMES SOABY, a seaman, aged 25 years, 
received into this hospital, the 25th of 
March last, from his Majesty's ship, Gram- 
pus, had the great toe taken off in the arti- 
culations of the first and second phalanx, 
about three months before, on the coast of 
Guinea; but being scorbutic, the skin had 
retracted, and the end of the stump was 
covered with fungus of a cartilaginous hard- 
ness, investing the artery. 
On the 26th of April, I amputated within 
the skin, sawing through the second pha- 
lanx. The blood gushed out in a stream 
nearly the size of a crow-quill, to the dis- 
tance of ten feet! I applied a small dossil of 
lint wet with the Styptic to the mouth of 
the artery, which my assistant retained, 
whilst I took a second dossil from a small 
portion of the solution in a saucer behind 
me;


(63)
me; on turning back to apply it, I found 
the bleeding was already entirely stopped! 
You can hardly conceive an adequate idea of 
my surprise on this unexpected event. 
CASE II. 
RICHARD BILBY, received into this 
Hospital 1st of August, 1785, from his Ma- 
jesty's ship, Ardent, had venereal tumours 
in succession, on each side of the os frontis, 
on the head of the radius and ulna, corro- 
ding the skin with a caries of the bones. In 
the April following, the tibia became affected 
attended with a profuse hæmorrhage from 
the arteries between both that and the 
fibula. Your Styptic was used here, with the 
greatest effect, and the patient was discharged 
in good health the July following. 
CASE III. 
JOHN LANGTON, a seaman, was
received in this Hospital, 13 Feb. 1786.
The third phalanx of the third toe was laid 
bare its whole length by a hurt in the month
of

(64)
of May, 1785, half the thickness of the 
bone exfoliated, considerable hæmorrhages 
followed, which stopped immediately on the 
application of your Styptic. 
This man was afflicted with epilepsy; in 
the fits he bruised the toe, and bled again 
several times. The Styptic on these occa-
sions was always used with success, and he 
was discharged perfectly cured, 14th August
last. 
CASE IV.
JAMES WARNOCK, a seaman, aged 
58 years, was received into the Hospital, 
May 25, 1786, from his Majesty’s ship, 
Pegase. In the night of the 24th he had 
been attacked by three men, who knocked 
him down with large rough flints tied in 
handkerchiefs, and cruelly beat him after- 
wards in the face and breast. The superior 
and external part of the os frontis was frac- 
tured, and a piece 12/10 by 8/10 depressed about 
half the thickness of the bone at the edges, 
with a fissure through it’s middle, where it 
was bent down the whole thickness of the 
skull,


(65)
scull, and a small acute angled part of the 
inner table beat off, and forced into the brain, 
particles of which lay on the hair with blood, 
from an artery on the dura mater, which was 
wounded by the splinter. 
Over the right eye was a large ragged 
wound, with the external table beat into 
the frontal sinews (whence I extracted five 
small pieces of bone) and two fissures run- 
ning into the superior part of the orbit of 
the eye. 
In removing the scalp from both frac- 
tures, the needle was rendered useless by the 
styptic. 
The patient had bled profusely before Mr. 
Hedington, surgeon of the Pegase, saw him 
and stopped the hæmorrhage; but so soon as 
the trephine acted on the depressed bone, the 
blood flowed again so freely, that I thought 
he would expire before he could remove it. 
When that was accomplished, the blood con- 
tinued to flow from under the edge of the 
firm bone, till the Styptic was applied, and 
directly stopped it. On the 28th in the 
morning, the pulse sunk, rigors and deli- 
I rium

(66)
rium came on, and he expired on the 29th, 
114 hours after the injury. 
CASE V. 
ISAAC KETTLE, seaman, aged twen- 
ty-two, was received in the Hospital 18th 
July 1786, from his Majefty’s ship, Media- 
tor, for the cure of a schirrous testicle, 
occasioned by a fall in the month of April 
before. 
The disease was rapidly advancing to a 
Carcinoma, when I extirpated on the 20th 
of August, having laid bare the spermatic 
chord from the abdominal ring to the en- 
larged Scrotum. I found I had not room to 
divide the chord first, therefore was under 
the necessity of dissecting upwards, and in 
this was greatly incommoded by the bleeding 
of an artery leading to the integument of 
the Penis, till a dossil steeped in the 
styptic intirely prevented further interrup- 
tions. 
CASE

(67)
CASE VI. 
JOHN DAVY, a seaman, received from 
his Majesty’s ship Salisbury, 16th June, 
1786, had a complicated fracture of the first
and second phalanx of the fore finger, with 
violent inflammation extending up the arm 
—He was of a scorbutic diathesis. 
On the 13th of September, the finger was 
removed at the articulation with the meta- 
carpus. On dividing the integuments be- 
tween the fingers, an artery was cut through 
obliquely, so that an oval orifice presented, 
and the blood gushed out with such force as 
to wet my shirt within my coat sleeve to the 
elbow. However inconvenient the needle 
would have been in a part like this, it must
have been used, had not your Styptic an- 
swered my expectations, and completely stop- 
ped the effusion. 
I am, Sir, 
Your most humble servant, 
Edward Young.
B. Ruspini, Esq. 
Pall-Mall. 
P. S. In consequence of the great effects 
from these trials of the Styptic, I made an 
I2 application

(68)
application to the board of Sick and Hurt 
for Haslar Hospital to be supplied with it 
—which, I have the pleasure to acquaint 
you, the Gentlemen of the Board readily 
granted. 
My Good Sir, 
WITH heartfelt pleasure I have perused 
your collection of communications, respect- 
ing your wonderful Styptic, and as the cha- 
racters of your correspondents are so very 
respectable, the most pertinacious Sceptic 
cannot surely withhold his assent to such 
strong, (give me leave to say), conclusive at- 
testations. I have been about fifty years en- 
gaged as a Surgeon and Apothecary, in the 
populous town of Ashburton, in Devonshire, 
long noted for its extensive Manufacture of 
Serges, to which its popularity is principally 
owing; and as I have had no inconsiderable 
share of business in each capacity, in the 
same town and neighbourhood; a great num- 
ber of patients with hæmorrhages, both from
external 

(69)
external and internal causes, have fallen under 
my care; and tho’ we have many preparati- 
ons, denominated Styptics, I have great rea- 
son to lament the inefficacy of them all, as I 
can with great propriety say, that on repeated 
trials I have not found any of them intitled to 
such an appellation; and now, My Good Sir, 
give me leave to rejoice in the opportunity of 
congratulating you on the possession of one of 
the greatest discoveries that ever was made in 
physic, or surgery; and whether it was the 
result of accident, or design, you have brought 
it into existence, and (me judice) deserve a 
statue in commemoration. Be so good as to 
let the gentleman who waits on you with 
this, have a bottle of the Solution that I may 
feel the exalted pleasure of adding another 
testimony, to the amazing powers of this in- 
valuable acquisition, and whatever the ex-
pence is, he is requested to pay it. 
I am, with great respect and esteem, 
My Good Sir, 
Your most obedient servant, 
Mich. Tripe. 
Ashburton, 
14th Feb. 1787.
Sunderland,

(70)
Sunderland, 26th April, 1787. 
Sir, 
WERE I to omit doing justice to that in- 
valuable remedy of which you have been the 
happy discoverer, and what is ultimately cal- 
culated to supersede those dangers arising 
from hæmorrhages in general; whether from 
disease, accident, or even in most chirurgical 
operations; I might justly reproach myself 
with being divested of the common feelings 
of humanity to mankind, and ingratitude to 
my Creator. 
A worthy gentleman of my acquaintance, 
much subject to expectorations of blood from 
the lungs, independant of any imposthuma- 
tions, and at one time reduced to a very low 
state, but was perfectly recovered by the skill 
of an eminent physician in this neighbour- 
hood, was the first who made me acquainted 
with the use and virtues of your excellent 
Styptic. 
And with pleasure I can assure you, that 
since his using it, he has experienced such 
salutary effects by doses of a tea spoon-ful 
now and then, that his complaint has always 
been

(71)
been kept entirely under, even by a single 
dose, and seldom more than two, for when- 
ever it makes its appearance, which it has 
done pretty often, he is sure to find the re-
medy in the life of your Styptic. 
The idea of such an effect being produced 
by it on a ruptured blood-vessel in the 
Lungs, is wonderful indeed, and strikes me 
with astonishment; had this discharge pro- 
ceeded from any part in the Prime Viæ, as 
the Æsophagus, Stomach, or any part in the 
intestinal canal, it might have been easily 
accounted for from the same effects that are 
produced by the same internal medicines. 
What qualities to ascribe to its operation I 
know not, neither shall I attempt it, being 
fully satisfied that while we are ignorant of 
its composition, we must be utterly at a loss 
to account for its effects, and were we ac- 
quainted with its ingredients, we should find 
ourselves still in the dark, at least it would be 
the case with myself. 
For when it is considered it is almost, if 
not altogether (I mean its taste) divested 
of astringency, pungency, or what is 
called stimilus, its effects are the more esti— 
mated. 
Who


(72)
Who in the world could ever imagine that 
a liquid, transparent and almost insipid fluid,
of a curious flavour, should exert such won-
derful effects; this is what excites our asto- 
nishment, and admiration, and leaves the 
mind in a perplexing, yet pleasing labyrinth; 
here methinks I have been tedious, and must 
proceed to relate you a case wherein its exter- 
nal effects were clearly shewn. 
An old man aged 70 or upwards applied 
to me for the cure of a large excrescence on 
his under Lip, of the cancerous kind. I tried 
several applications for some time, but with- 
out effect: the operation of extirpation being 
resolved on, I performed it in the presence 
of Mr. Akenhead, a Surgeon of eminence 
here, and some other gentlemen; the sur- 
face after the operation was performed, was 
nearly an inch and a half; the vessels, (which 
in cases of this sort) were particularly en- 
larged, of course the hæmorrhage was very 
profuse, and the blood flowed with great ve- 
locity to a considerable distance, and issued 
out of several of the smaller vessels; a single 
piece of thin lint was dipped in the Styptic, 
and applied to the surface, pressed on for one 
minute or very little more, and then the
hæmorrhage

(73)
hæmorrhage ceased, and what increased my 
astonishment the more, was, that he felt no 
pain from its application, and notwithstand- 
ing the old fellow laughed at something very 
heartily that had been said at the time, yet 
no appearance of blood followed, and I be- 
lieve he never hindered himself from talking 
at all. 
I have every reason to expect success from 
the operation, and can assure you, that he is 
far from pain, and little or no inflammation 
has appeared, as the operation was performed 
but yesterday. 
If you think, this letter will be of any use 
to society, or yourself, may publish, or 
make what use you please of it, in the 
interim. 
I remain, 
Your's respectfully, 
Geo. Wilkinson, Surgeon. 
K The

(74)
The CASE of 
LADY COCKBURN. 
Her Ladyship was suddenly, and most 
violently seized with a profuse hæmor- 
rhage from the nose, which alarmed the 
whole family for her safety; but fortu- 
nately having a bottle of Mr. Ruspini’s 
Styptic in the house, a quantity of it was 
applied, as ordered in the printed directions, 
and the bleeding thereby immediately re- 
strained. 
Her Ladyship had no return, and soon 
after called on Mr. Ruspini to thank him, 
and to give this account of the great benefit 
she had experienced from so valuable a 
medicine. 
A Case of Bleeding from the Lungs, 
cured. 
Mrs. Ppiladelphia Langridge, at 
Lime-house Causeway, had a very bad 
cough, which affected her lungs so much,
that

(75)
that a very considerable quantity, at first, 
of coagulated, and at last, of fluid blood, 
was coughed up. Dr. De Valengin having 
informed Mr. Smith, Surgeon of Limehouse, 
of the great efficacy of Mr. Ruspini’s Styptic 
in restraining internal, as well as external 
bleedings, induced Mr. S. (who was here 
consulted) to recommend it. It produced 
the most happy and salutary effects: Mr. 
Boys, surgeon, of Berners-Street, saw her 
some days after the hæmorrhage had been 
stopt, when she informed him of it, and added, 
that her cough and general health were much 
better; and, that she had not bled a drop 
since she took the Styptic Solution. 
Since the above case, which was inserted 
about six months ago in the newspapers, Mr.
Ruspini has the pleasure of hearing that she 
has had no return whatever of the complaint. 
She took in the whole seven bottles of the 
Styptic Solution.
K2 A


(76)
A Gentleman of the first Character in the 
Country and late a Member of the British
Senate, gives Mr. Boys, Surgeon of Ber-
ner’s-street, another proof of the efficacy 
of Mr. Ruspini’s Styptic Solution. 
A poor woman chopping wood with a bill-
hook, missed her stroke, and cut the arteries 
of her left wrist; no surgeon being within 
seven miles, she must probably have bled to 
death, had hot the Styptic been at hand; the 
gentleman applied it with its usual good ef- 
fects, and in a short time the woman was 
well. 
ANOTHER CASE. 
Mrs. Lane, No. 10, Hanover-Street, 
Long-Acre, was seized with a violent bleed- 
ing at the nose, which continued (in spite of 
all endeavours to stop it) four days; when 
the application of the Styptic immediately 
cured it. 
The

(77)
The following Letter, Mr. Ruspini had the 
Pleasure of receiving from Edward 
Young, Esq. Surgeon General of the 
Royal Hospital, Haslar. 
Dear Sir, 
YOUR favour of the 25th, gave me 
particular pleasure, because, I believe that 
the Royal Artillery, from the nature of their 
service, must give Mr. Irwin frequent occa- 
sions to apply your Styptic; and that the 
universal esteem which that corps possess, 
will cause more attention to be paid to his 
report of it, both, by people of consequence, 
and by the profession, and render its great 
utility more universally known. I greatly 
long to hear from India, and hope the facul- 
ty there will give it fair trials; then I doubt 
not but their report will convince the Direc- 
tors that they have bestowed a blessing upon 
the Company’s Soldiers and Servants in this 
part of the world. 
The seamen of his Majesty’s ships which 
come to this port, have lately been so fortu- 
nate, that of 420 surgery patients received 
into this hospital since October, only two 
cases

(78)
cases of any consequence occurred, in which 
I had recourse to it, and neither of those were 
capital; though one was of such a nature as 
proves that the Solution will stop bleeding in 
every case when it is properly applied; and 
the other leads me to believe that it will prove 
to be a very useful application in other cir- 
cumstances. 
On the 27th of January, 1787, Grenville 
Martin, was sent to this hospital from his 
Majesty’s ship, the Leander, by falling on 
his breast a considerable height, he was seized 
with an hæmorrhage from the navel, which 
had the appearance of a deep ulcer, about 
the size of half a crown; though the blood 
oozed from invisible points in the ulcer, their 
number discharged an alarming quantity of 
arterial blood, especially as proper means to 
stop it had been used in vain, before I saw
him. He informed me that he had been 
subject to umbilical hæmorrhages from his 
birth, it being occasioned by the carelessness 
of the midwife; in his youth his life had fre- 
quently been in danger from it, but that since 
he arrived at man’s estate, it had never return- 
ed, but on exerting his, utmost strength; and 
that it had never been so as at this time. Not 
being


(79)
being able to distinguish the mouths of the 
bleeding vessels, I had little expectation of 
sudden success, however I filled the cavity 
with dossils of lint wet with your Styptic So- 
lution, with gentle pressure and retentive 
bandage. The dressings remained on three 
days, when there was not the least appearance 
of blood. 
Peter Burges, was received on the 13th 
of January, 1787, from his Majesty’s ship the 
Myrmidon for the cure of the scurvy, ha- 
ving likewise a truly scorbutic ulcer on his 
inner ancle, which had been injured in action 
in the late war. Notwithstanding the regi- 
men, medicines, and applications usually em- 
ployed with success in that disease, the ulcer 
became larger, and a part of the cartilage cast
off from the end of the Tibia, the edges of 
the ulcer were swelled and inverted, and at 
every dressing a large coagulum of black 
putrid blood covered the whole sore, and 
the discharge of bloody sanies through the 
dressings was more profuse than I judged his 
strength could support much longer; about 
a week ago, I dressed the whole ulcer with 
lint moistened in the Styptic. The good ef- 
fect


(80)
fects of this one dressing far exceeded my ex- 
pectation, for the discharge has been good 
pus ever since, and from the present appear- 
ance, I have no doubt of saving the limb. 
As I intend to send a bottle with a pam- 
phlet to a pupil of mine, now settled at 
Newfoundland; I take the liberty to beg a 
double set of the sheets of your new edition, 
after Page 110, of the last, and that you will 
be pleased to forward them by the post, one 
sheet under each cover.
I beg leave to present my most respectful 
compliments to Mrs. Ruspini, and to your 
young Gentleman. 
Dear Sir, 
I am, 
Your most humble servant, 
EDWARD YOUNG. 

(81)
Mr. Ruspini, in addition to the nume- 
rous and most respectable attestations of the 
efficacy of his Styptic Solution, has the plea- 
sare of presenting the public with the follow- 
ing important cases, communicated to him 
by James Irwin, Esq; Surgeon General of 
the Royal Hospital at Woolwich, and the 
Royal Artillery. 
Royal Hospital, Woolwich, June 9th, 1787. 
Sir, 
It gives me singular satisfaction to have it 
in my power to communicate to you the fol- 
lowing intelligence respecting your valuable 
Styptic.
About three months since; I accidentally 
mentioned to the worthy clergyman of this 
parish, that a respectable character, our ac- 
quaintance, was afflicted with an internal 
bleeding; my friend then ask’d me, if I had 
ever made use of any of your Styptic; and at 
the same time handed me the remarkable 
cases already published, which induced me 
to send for a bottle: As the person whose 
case I hinted above, soon got better, I had no 
L opportunity

(82)
opportunity of making any experiment until 
the following relations occurred, Viz. 
CASE I. 
February 21st, 1787, Alexander Da- 
vidson, a bombardier, afflicted for several 
months with an hæmoptoe, received present 
relief, by taking two tea-spoonfuls of your 
Styptic in a cup of tea, every two hours: and 
altho' the quantity of blood he used to bring 
up daily, was very great, yet the continuance 
of the Styptic for a few days entirely stopped 
the bleeding, and he remained in perfect health 
for near two months; but on his living irre- 
gularly, and drinking too much, the bleeding 
returned again, but on using the Styptic as 
before, it had the same effect, and he has 
continued in perfect health ever since. 
CASE II. 
March 5th, 1787. George Glassup, 
was troubled with a spitting of blood, for two 
months, and was cured by taking a small 
spoonful of the Styptic, twice every day, and 
is now in perfect health. 
CASE

(83)
CASE. III. 
March 8th. Thomas Irons, a young 
man not twenty years of age, second gunner 
in the Royal Artillery, received a wound 
across the wrist, with an hanger, which 
divided the artery, which bled violently: all 
the usual methods were tried to stop it, but 
without success; when a pledgit of lint dipt 
in your Styptic, being applied, the bleeding 
stopped presently; and on opening the wound 
next day, (which I did on purpose to see the 
effects of the Styptic) on removing the lint, 
it bled as before, when a fresh application of 
lint moistened with the liquid, stopp'd the 
bleeding instantly, and it never bled any more: 
the wound digested, and healed kindly. 
CASE IV.
May 2d. John Walker, a Gunner, 
had a tooth drawn, on which a violent bleed- 
ing ensued; the common methods were used 
to stop it, but in vain: when a dossil of lint 
L2 dipt

(84)
dipt in the Styptic had the desired effect im- 
mediately. 
N. B. A similar instance happened to Duncan McIntosh,
where the Styptic was applied with equal success. 
CASE V. 
May 15th. John Bell, an invalid Gun- 
ner, received a wound across the back part 
of his head; he applied to a surgeon in the 
town, who tried the methods made use of in 
such cases, without effect: The man was sent 
to this hospital, where the surgeon on duty 
applied pledgits of lint, moistened with your 
Styptic, which stopped the bleeding instant- 
ly; and the wound soon after healed. 
It appears to me that future experiments 
will shew that your Styptic is a most power- 
ful remedy for the cure of all kinds of hæmor- 
rhages. 
James Irwin, 
To B. Ruspini, Esq; Pall-Mall.
The 


(85)
The following case was sent to Mr. Ruspini 
by Mr. Dodo Eeken, one of the Sur-
geons of the Royal Artillery. 
DUNCAN M'INTOSH, 
The 4th of May, 1787, had a tooth drawn, 
in consequence of which, the day after he 
came to the hospital to have the blood stopt, 
which had been constantly flowing * from the 
time the tooth was extracted; Mr.Eeken tried 
every method surgery suggests, in vain, and 
his only resort he was afraid, would, and 
must have been Actual Cautery (that is, a 
red hot iron) when he detemin’d to try Mr. 
Ruspini's Styptic.—A small quantity of it 
was applied to the socket, and in a quarter 
of a minute the bleeding ceased. 
D. Eeken. 
* A Lady at Wandsworth had a similar misfortune happen 
in the extraction of a Tooth; and being of a diseased delicate 
habit of body, the quantity of blood lost made the Physicians 
despair of her recovery: She did not use Mr. Ruspini’s 
Styptic. 
On

(86)
On Friday, the 1st of June, 1787, Mr. 
Boys, surgeon, of Berners-street, was sent 
for to Mrs. Ann Field, (No. 24,) Charles- 
street, Middlesex-Hospital, who had then 
cut nearly off, a large portion of the fleshy 
part of her thumb; he found her not quite 
recovered from an alarming fainting fit, a 
large quantity of blood on the floor, and the 
piece of flesh detach’d from the bone; he 
immediately applied the Styptic, and the 
blood stopt. Throughout the whole cure, 
which was effected in nine days, the only 
medicine used was the Styptic. 
June 4th, 1787. John Saunders, 
(No. 92,) Hatton-Garden, sent for Mr. Boys, 
to take out a portion of nail that grew out of 
the great toe, attach’d to the nail; the aspe- 
rity of it had produced considerable ulceration 
round the inside of the nail, with great pain 
and inflammation.—In cutting it out, a con- 
siderable hæmorrhage followed the knife, 
which was immediately stopped by the Styptic.
’Tis

(87)
’Tis near six days since the operation was 
performed, and no other application but the 
Styptic has been used. The toe is in the 
fairest way of getting well.
Mr.


(88)
Mr. Ruspini has many other Let-
ters in his possession, some of which are 
from Persons of the highest Rank and most 
distinguished Abilities; but these he shall 
not publish, unless requested so to do- 
but the Testimony they all bear to the 
Efficacy of this great Medicine, may be 
seen by any Person who will call on Mr. 
Ruspini. 
East Grinstead, Oct. 22, 1787. 
SIR, 
THOUGH the following case does not af- 
ford so striking a proof of the valuable effects 
of your Styptic as many others have done, yet 
the relation of it may in some measure tend to 
promote the use of a medicine in itself so 
truly valuable, and at the same time commu- 
nicate a degree of pleasure to the inventor; is 
as follows: 
Mrs. J—n, an inhabitant of this town, who 
has for many years been afflicted with a cancer 
in her breast, and from which she was sub- 
ject to frequent and sometimes profuse hæ- 
morrhages, but which to that period had
always

(89)
always yielded to common applications, such 
as lint, vit. cerul. and the common styptics. 
She was attacked with a return of the 
hæmorrhage one morning, and though at 
first it came on as usual in a slight degree, yet 
by the afternoon it was much increased, and 
by the evening of that day, which was the 
time I was sent for to her, the loss of blood 
had been very considerable; the arm on the 
side where the cancer was, I found consider- 
ably enlarged by an œdematous swelling, and 
the poor woman near fainting from the loss 
of blood; when I attempted to remove the 
lint, which had been unsuccessfully applied, 
the hæmorrhage increased very much. Find- 
ing her so circumstanced, I determined to 
lose no time, but to have immediate recourse 
to your Styptic;—the valuable effects of 
which were so strongly imprinted in my 
mind, in the case of David Knox, Esq. of 
Crawley Down, (as related by my predeces- 
sor Mr. Young) I moistened a large pledgit 
of lint with the solution, and applied it to the 
cancer, and to my great satisfaction the effect 
was instantaneous, the hæmorrhage immedi- 
ately ceased, and I have not heard that she 
has had a return of it since; this is all I think 
worth mentioning on the subject—and I shall 
M think


(90)
think myself happy if by making one amongst 
the many medical gentlemen who have trans- 
mitted to you an account of the valuable 
effects of your Styptic—if I have in any degree 
contributed towards the advancing the use of 
a medicine so justly meriting universal appro- 
bation. Should any other circumstance, 
worth relating, occur in my practice, you 
you may rest assured I shall always be ready to 
communicate it with pleasure. 
I am, Sir, 
Your most humble servant,
R. Hilton.
To B. Ruspini, Esq.
Pall-Mall.


(91)
To B. Ruspini, Esq. Pall-Mall. 
Droxford, Hants, Nov. 17, 1787. 
Sir, 
YOUR favor dated the 3d instant, by 
having been missent to Winchester, &c. &c. 
did not reach me till the 11th, since which 
particular business has prevented me from 
answering it. I was in town the beginning 
of last July, and then called twice on you, 
intending to have given you the case William 
Buckland wished me to communicate to you,
but you not being at home either time, and 
having sent for a bottle of your most excellent 
Styptic from your house, which was accom- 
panied with one of your pamphlets, contain- 
ing a great number of different cases from 
gentlemen of the greatest respectability in the 
medical and chirurgical professions, wherein 
it had uniformly been applied with all imagi- 
nable success, prevented my sending the fol- 
lowing one, which I conceived not to have 
been of equal importance with many others 
contained in your book. The case under my 
care was as follows: W. B. Price, journey- 
man blacksmith to Mr. J. Been, Soberton, 
M2 Hants

(92)
Hants, a healthy young man, aged about 22, 
June 15, 1786, had the misfortune either 
from accident, or an incautious use of the 
instrument used in paring the hoofs of horses 
before they are shod, called the battrass, to 
have it enter the left wrist, near the part 
where we usually examine the pulse, and 
divide the radial artery, in an oblique direc- 
tion, but perfectly through the vessel, as was 
discovered on a careful inspection, though the 
wound from having been made with only the 
corner of the instrument, was small, the 
consequence, as might be expected, was a 
very profuse hæmorrhage, and though his 
master, Mr. B—, a farrier also, to whom 
he had been carried near three quarters of a 
mile farther from me for his assistance, and 
many other persons had tried all the common 
customary country applications, such as, 
flour, cobwebs, tow wet with oil of turpen- 
tine, &c. &c. together with bandage, though 
improperly applied below the cubitus, and 
consequently without the wished for effect. 
It is supposed by the time I reached him, he 
had lost near three quarts of blood, (though 
I myself could not think quite so much) and 
indeed his appearance, with other circum- 
stances too tedious to enumerate, plainly indi-
cated


(93)
cated the loss of blood to have been very con-
siderable, yet all applications hitherto had 
been ineffectual, though the bleeding was 
not near so violent as it had been. The mes- 
senger who had been dispatched for me in a 
hurry, brought a very imperfect account of 
the case, which I did not apprehend had been 
nearly equal to what I found it. I attended 
instantly, and saw him in about an hour or 
something more after the accident. The 
blood being in some measure stopped, I ap- 
plied a suitable bandage above the cubitus, 
and had him properly conveyed home to his 
master's house, and then cleared away every 
thing that been before applied to the vessel, 
loosened the bandage, and applied dossils of 
lint wet with the tinct. styptic helvetii, suit- 
able compresses, &c. a sufficiently light band- 
age to restrain the present returning copious 
bleeding, and ordered every necessary care to 
be taken of him till the next morning, and 
that if the bleeding should return they would 
send to me again as soon as possible. I had 
just before heard of your Styptic, knew the 
Hon. the Countess Dowager of Clanricarde 
in this village had some of it by her, and 
thought this a favourable opportunity if the 
bleeding returned, to try its efficacy; I there- 
fore


(94)
fore desired the favor of her Ladyship to spare 
me some of it in the evening, fearing I might 
be again called on; indeed I should have secur- 
ed the vessel by ligature, had not this circum- 
stance recurred to me, and which I must 
otherwise have done, or suffered my patient to 
have run the-hazard of a fatal syncope from 
the want of it; a most painful operation I 
wished to spare him the pain of, had not so 
powerful a remedy as your Styptic been at 
hand. Her Ladyship, with the greatest hu- 
manity and good nature, offered me any 
quantity I might want. Being called early 
next morning, on account of fresh hæmorr- 
hage, I went to my patient, found he had 
bled it was supposed near a pint, which had 
reduced him a good deal. I cleaned the 
wound from the former applications and the 
coagulated blood, and applied your Styptic 
on lint, agreeable to your directions, holding
it on the part for two or three minutes, and 
to my astonishment it hardly bled through the 
lint afterwards. I applied a fresh piece of lint 
with it over the other, and used no more than 
bare moderate retentive bandage, and yet it 
never bled any more, neither did I apply any 
thing else but the Styptic to the wound after- 
wards, and it incarned exceedingly well and 
soon

(95)
soon healed. I am exceedingly glad to see in the 
last edition of your pamphlet, that it has been 
so wisely ordered for the use of the royal navy, 
as well as for the East India settlements, 
ships, &c. and hope it will ever meet the same 
success I have found from its application. I 
assure you, Sir, I intend never to be without it 
by me, as I look upon it to be the desidera- 
tum long wished for by every gentleman in 
the practice of surgery, as it is too well known 
all those medicines usually called styptics, be- 
fore in common use, were in cases of moment 
little to be relied on, and rendered a necessity 
for that very painful operation of ligature by 
the needle, too frequently necessary. I could 
with every gentleman of the faculty in the 
kingdom, might take care to supply himself 
with some of it, who has more frequent op- 
portunities of using it with advantage and 
credit to himself, as well as ease to his pati- 
ent; and that country gentlemen of fortune 
in general, and more particularly those who 
are remote from proper assistance, would 
keep it by them for the use not only of their 
own families on emergencies, but also for the 
assistance of the poor in their neighbourhood, 
in cases of accident; to whom in many in- 
stances that may occur, from both external 
as


(96)
as well as internal causes that may happen. It 
may be the means of perhaps even preserving 
the lives of many individuals, to the comfort 
of themselves and families, as well as receiv- 
ing themselves that God-like satisfaction of 
having been the means of rendering so essen- 
tial a service to their fellow-creatures. 
I am, Sir, 
Your most humble servant, 
Wm. Rogers. 
Surgeon and Apothecary. 
P. S. I have mentioned your name to the 
Right Honourable the Countess Dowager of 
Clanricarde, to whom I find, and family you 
are well known. Her Ladyship constantly 
keeps a supply of your Styptic by her, and 
proposes never to be without it, having ex- 
perienced two or three times a copious, and 
once rather alarming nasal hæmorrhage. 
Royal

(97)
Royal Hospital at Haslar, Nov. 25th, 1787. 
Dear Sir, 
I SEND the following account of a case, 
in which your Styptic was used with success; 
not because, I think that farther proofs of its 
power are necessary to establish its character, 
but that I might add to the pleasure so valua- 
ble a discovery must give you from its exten- 
sive utility; and, that I may at the same 
time pay the tribute of gratitude due to you, 
for having been the means of obviating the 
necessity of my performing an operation 
always disagreeable to a Surgeon, as well as 
painful and dangerous to the patient. 
John Ebbets, Quarter Gunner, was re- 
ceived into this Hospital on the 19th instant, 
from his Majesty’s ship the Salisbury. That 
ship arrived at Spithead from Newfoundland 
the day before, and in saluting the Comman- 
der in Chief, a cartridge containing between 
five or six pounds of powder, by some acci- 
dent took fire as this poor man was ramming 
it into the gun. His right hand was shatter- 
ed, the osbrachiale fractured in several places,
N the 


(98)
the skin of the arm burnt to the axilla, and 
the face and eyes scorched. About five 
o’clock that evening the arm was amputated; 
about eleven the next morning he was brought 
into the hospital.—Notwithstanding a tour- 
niquet was on the stump, and screwed up, 
there was a considerable hæmorrhage, so that 
I was under the necessity of removing the 
first dressings immediately. To observe that 
the operation had been well performed, would 
be unnecessary, but for the purpose of giving 
you an adequate idea of the force of the hæ- 
morrhage, by describing the quantity of 
blood discharged in about eighteen hours. 
The bone was sawed off above the insertion of 
the deltoid muscle, the arm is fifteen inches 
in circumference, and there being skin enough 
preserved for its edges to meet in a line over 
the face of the stump, leaves a cavity of five 
inches in diameter, and two inches and a half 
in depth; all this space was filled with tensly 
coagulated blood, besides the serous part of 
the blood which had escaped through the 
dressings, and a considerable quantity which 
had flowed up the stump and over the ban- 
dage, and run down his back and sides. 
Having

(99)
Having removed the coagulum, I percei- 
ved that the surgeon had been obliged to 
secure with ligatures no less than six arteries; 
and that this large quantity of arterial blood 
proceeded entirely from the hollow cylinder 
of the bone, whence by its momentum, it 
had forced the marrow for about half an inch 
in length. 
Some small dossils of lint moistened in your 
Styptic being ready, one was placed in the 
cavity of the bone the instant the sponge was 
removed, and a second on that. 
The dressings were renewed Thursday 
morning the 22d, and every morning since, 
without the least appearance of blood, though 
this morning he complained greatly of pleuri- 
tic pains. However, this evening I had the 
pleasure to find him easy and in all other 
respects as well as can be expected. 
So soon as I saw what the case really was, 
I relied on your Styptic; had that failed me, 
perhaps the necessity of the occasion might 
have inspired other resources; but now that 
is over, and in my cool minutes I confess, 
that nothing occurs that could have saved the 
poor man’s life, considering all the circum-
N2 stances 

(100) 
stances of the case, but that of amputating in 
the articulation. 
I must not omit this circumstance. One 
of my assistants who had never seen the 
Styptic used before, asked the patient while 
I was pining the bandage, “ if he felt any 
pain?” his answer was, “ He was in a deal 
of pain before he was dressed, but was easy 
now.” “ But did it not smart when the 
medicine was put into the bone?” his 
answer was, “ No, not at all.” My own 
mind was too much engaged to permit me to 
think of pain, but I was much pleased that 
the question was asked; more so with the 
answer, which indeed was confirmed by his 
sleeping all that day and night, except when 
thirst awakened him, but then he fell asleep 
directly after drinking: indeed, though I 
saw him several times a day, I had no oppor- 
tunity of speaking to him till Wednesday 
morning, when his wife arrived. 
I see that I have been very prolix, but I 
have more than two hundred and twenty 
patients under my care in this hospital, many 
of them very heavy cases; you will there- 
fore conclude that I am too much fatigued 
to

(101)
to correct that and other faults, and excuse 
them in 
Dear Sir, 
Your very humble servant,
Edward Young. 
B. Ruspini, Esq. 
Pall-Mall. 
Sevenoaks, Kent, Nov. 26, 1787. 
Sir, 
I shall be very much obliged to you, to 
send per bearer a bottle of your Styptic, he 
has directions to pay for it. 
I had the happiness to experience its effi- 
cacy in an hæmorrhage from the nose, where 
a gentleman had tried every other method 
without success. 
In the case of a lad who had nearly severed 
the top of his thumb, an artery bled very 
much, a small piece of lint wet with your 
Styptic, and held on by my finger, instantly 
stop it. 
A

(102)
A gentleman of the profession had made a 
small incision on a phymosis, and it being on 
the upper part oi the penis, the artery bled 
freely, he stopt it by pressure; but the lad 
walking home it bled again so violently that 
it could not be suppressed, the Gentleman 
knowing I had some of your Styptic, sent for 
it, and had the candour to acknowledge, 
that a small piece of lint wet with it, and laid 
on tight with his finger, stopt it instantly. 
By one of those revolutions in practice 
which frequently happen, the lad became 
my patient; I found it necessary to divide 
the pressure ad coronam glandis, and know- 
ing the efficacy of the Styptic, I did not fear 
doing it in the upper part, (though the lad 
lost, as he assured me, three quarts of blood 
before your Styptic was used in the former 
small division) I divided the artery quite in 
the middle, and the blood spun freely per 
saltum; but my assistant applied the Styptic 
instantly, and not two ounces of blood were 
lost on my honour; how much more must 
have been lost before a ligature could have 
been applied, and in all probability the life 
lost, as he was so reduced and emaciated, as 
not

(103)
not to be able to stand or sit up, from the 
great previous loss. 
Your Styptic has a farther advantage over 
ligatures, in removing easily the next day, 
without any inconvenience or hæmorrhage 
ensuing. 
I have not made use of it internally, but 
certainly should if occasion required. 
I have mentioned it to every person in this 
neighbourhood, many of whom independent 
people, have furnished themselves with it. 
I feel vasty interested in the success of it, 
and your receiving a compensation in some 
way; but it must be totally inadequate to so 
great a benefit. 
You are at full liberty to make use of these
cases in any way you please, and I am, with 
the most unfeigned respect, 
Sir, 
Your very humble servant,
Thomas Baker.
B. Ruspini, Efq. 
Pall-Mall. 

(104)
Kentish Town, Dec. 3, 1787. 
Sir,
BEING informed by the Rev. Mr.
Wycher, that you were going to publish 
some cases on your Styptic, I send you the 
following, and should any other cases occur 
in my practice you may depend upon having 
them related with impartiality. 
I am, Sir, 
Your humble servant,
J. Rogers. 
[CASE Jan. 4th, 1787.] 
Mrs. CLARKE, of Green-street, Ken- 
tish Town, was suddenly seized with a vio- 
lent hæmorrhage from the nose, from a fit of 
coughing, and lost a great quantity of blood; 
I tried every thing in my power, and not- 
withstanding the hæmorrhage returned, but 
by applying your Styptic as directed, it en-
tirely stopped, nor has it returned since. 
To B. Ruspini, Esq;
Pall-Mall. 

(105)
Mr. Ruspini, thinks it may be necessary to 
subjoin the following attestation, on 
oath, of the wife of a poor man, who 
was so miraculously cured-in July last of 
a dreadful internal hæmorrhage. Any 
lady or gentleman desirous of asking why 
the simple relation of the fact, would not 
have sufficed, may have the fullest satis-
faction of Mr. Ruspini. 
“ JANE the wife of John Lee, of Cum-  
berland-Court, Middlesex Hospital, maketh 
oath, and faith, that her husband was seized 
with a violent vomitting of blood, on 
Saturday three weeks last past, about two 
o’clock in the morning; that on Sunday 
morning about nine o’clock, this deponent 
sent for Mr. Dawes, Apothecary, in New- 
man-street, who came immediately, and 
presented such medicines as he thought pro- 
per; that in the course of the day he paid 
her husband five visits, that when he came 
the last time, about six or seven o’clock in 
the evening, and not finding the said John 
Lee better, he desired this deponent to take 
with all speed a written direction to Mr. 
Ruspini, Surgeon-Dentist, in Pall-Mall, 
O all

(106)
all which this deponent faith was written 
in her presence, by the aforesaid Mr. Dawes, 
requesting a bottle of styptic solution, 
might be given to the bearer; this deponent 
also verily believes her aforesaid husband lost 
TWO GALLONS of BLOOD, that he 
found immediate relief from the use of the 
Styptic, for that the blood stopt after the 
first or second dose; and that she is sure he 
owes his life to the STYPTIC SOLUTI- 
ON.” 
July 23d, 1787, 
Sworn before me,
William Addington. (Copy) 
This the X mark of 
Jane Lee. 
ADDENDUM. 
Mr. Ruspini has cases in his possession, 
where the styptic solution has proved a re- 
medy for the Fluor Albus.—The impossibility 
of publishing these cases is evident; but one 
of them contains the case of a lady who was so 
relaxed, and so languid by the continuance 
of the discharge, that the least exercise be-
came

(107)
came painful. The mode in which the 
Styptic is used in this complaint, is by injec- 
tion.—Inject a syringe full of green tea, about 
the same strength it is usually drank, and im- 
mediately repeat the same. Lastly, inject a 
table spoonful of the Styptic Solution, which 
is to be continued every night and morning. 
The following important Cases were trans- 
mitted to Mr. Ruspini, by Mr. Coombe, 
an eminent surgeon at Woolwich. 
CASE I. 
A Lady from London residing at Shooter’s 
Hill for the benefit of the air, was there seized 
with an internal hæmorrhage, voiding by 
stool a large portion of fluid, and some coagu-
lated blood; in this state Mr. Coombe saw 
her, and continued to attend her near a week, 
during which time the most judicious pre- 
scriptions were administered without success; 
at last the worthy clergyman of Woolwich, 
O2 the

(108)
the Rev. Mr. Tullough, recommended to 
Mr. Coombe the use of Mr. Ruspini’s Styp- 
tic; by this time the bleeding had increased 
to a most alarming degree, the pulse was low, 
the extremities cold, and the patient evidently 
in the most hazardous state; here was no 
room for debate. On the respectability there- 
fore of the recommendation, Mr. Coombe 
began by giving her two teaspoons-full every 
two hours in a draught of emulsion. The 
first dose was thought to have lessened the 
bleeding; the second dose evidently did so; 
the third restrained the fluid blood, and the 
fourth entirely stopped it; to this may be 
added she has ever since enjoyed uninterrup- 
ted good health. 
CASE II. 
AN elderly lady in the dock yard, at 
Woolwich, had been subject for some years 
past, to violent irregular, periodical dis- 
charges from the uterus; for the cure of which 
attempts had been made by many eminent 
gentlemen of the faculty: the last that she 
consulted was Mr. Coombe; this Gentleman 
after so fully experiencing the potent effects 
of the Styptic in the first case, did not hesi-
tate 

(109)
tate, in the least, to prescribe it in this; but 
as his patient, joined to great delicacy, was 
extremely low and nervous, he did not inform 
her he intended to administer the Styptic; 
a few doses, however, of which, soon re- 
moved the complaint; and she remains well. 
CASE III. 
MASTER CONGREVE, the son of 
Major Congreve, while labouring under the 
pressure of a violent fever, was seized with a 
bleeding from the nose; the Styptic Solution 
was immediately applied, and the hæmorrhage 
thereby cured. 
Woolwich, April 2d, 1788. 
The

(110)
The following cases were given to Mr. Rus- 
pini by Mr. Davis, a surgeon of great 
eminence at Mortlake, in Surrey. 
CASE IV. 
SARAH WEST, of Barnes, in Surrey, 
with a large broken glass bottle, divided the 
muscles, tendons, and of course the arteries 
in her wrist, down to the bones. When I 
first saw her, the blood leaped forth from 
both arteries with great velocity, as it always 
does when large vessels are divided: I deter- 
mined immediately to try the Styptic, and 
endeavour to heal the wound by what is 
called the first intention, on applying the 
Styptic to the divided vessels, and holding it 
there a small space of time, the hæmorrhage 
stopped. I secured the application by proper 
bandage, and did not open the wound till the 
ninth day, when I found it so nearly healed, 
that a repetition of my visits became unneces-
sary; and the woman is quite well. 
The


(111)
The next case of Mr. Davis’s places the 
virtues of the Styptic in a new light, Mr.
Ruspini would esteem it a particular favour, 
if gentlemen of the faculty should think pro- 
per to try it in similar, or in any highly putrid 
case, if they would accurately transmit an 
account of its success, or failure, to him. 
It must be allowed, in these very dreadful 
visitations of the Almighty, that all human 
efforts even to give relief, too generally prove
abortive; and to restore the body to health, 
seldom falls to the lot of the most skilful
practitioner; that Relief was here found by 
the styptic, Mr. Davis strenuously asserts: 
and avowedly declares it his opinion, that had 
the styptic been given in the earliest stage of 
the disease, the Life had been saved. 
CASE V. 
MARY WHITE, of Barns, in Surry, 
was taken suddenly ill, with the usual and 
most distressing symptoms of the confluent 
small pox: it is unnecessary here to enume- 
rate all the dreadful accompanying symptoms, 
suffice it to say, that on the fifteenth day, 
the body was covered with innumerable con- 
fluent

(112)
fluent ulcerations, emitting a stinking, bloody 
sanies; as the bark, cordials, &c. &c. had 
long been given without effect, it struck me 
that Mr. Ruspini’s Styptic might do some 
good in restraining the bloody sanies and 
finding it had been given liberally, and suc- 
cessfully internally, I thought myself fully 
justified in trying the experiment, as a dernier 
resort. Two teaspoons-full, therefore, of it 
was given, and was repeated every four 
hours; after a few doses had been taken, the 
patient expressed her satisfaction at the relief 
she obtained by it, and the next day I had the 
pleasure of seeing the bloody sanies putting on 
the garb of matter; in short she was evidently
relieved by the styptic; but nature could not 
hold out against so powerful an enemy, and 
on the twentieth day she died. 
I think I should not act the part of a can- 
did, or indeed an honest man, if I did not 
inform Mr. Ruspini, how high in my esti- 
mation his Styptic ranks, for I here am firmly 
of opinion, had the Styptic been given, as soon 
as it became necessary to give the bark, &c. 
&c. the woman would have struggled through 
the disease. 
Mortlake, April 17th, 1788.


(113)
CASE VI.
THOMAS BATHE, a waiter at Wood’s 
coffee-house. Covent Garden, was seized 
with a profuse hæmorrhage from the nose, 
and in the space of twenty four hours lost 
near two quarts of blood, the bleeding thus 
continuing, and the man growing faint with 
loss of blood, late at night sent to Mr. Rus- 
pini for a bottle of styptic, the liquid was 
applied as directed, and the hæmorrhage 
thereby cured. 
Wood’s Hotel, April 18th, 1788. 
CASE VII.
Mr. RICHARD SWAYNE, No. 28,
Oxendon-street, was seized with a most pro- 
fuse hæmoptoe, or bleeding from the lungs, 
for which the consulted a surgeon of emi- 
nence, who after bleeding him, and prescri- 
bing what he thought proper without in the 
least retraining the hæmorrhage, advised 
him to the use of Mr. Ruspini’s styptic 
solution: this was given, two teaspoons-full 
at a time every two hours, a very few doses 
lessened the discharge, and continuing its use
P about 


(114)
about twenty hours, the bleeding was entirely 
restrained, and Mr. Swayne continues well. 
In this case the supposed quantity of blood 
that came from the lungs in about six days, 
was more than Two Gallons. 
No. 28, Oxendon-street, 30th April, 1788. 
Sir, 
Last Easter Monday I was seized with a 
violent fit of coughing, and in the course of 
some hours, vomited above three quarts of 
blood: greatly alarmed at this event, I went 
as soon as possible, to seek medical assistance: 
on my way the bleeding returned, and issued, 
like a torrent. On my arrival at the house 
of a surgeon and apothecary, I discharged, 
in his presence, a considerable portion more. 
After this, he bled me in the right arm, 
and having prescribed, ordered me to keep 
myself very still and low, adding, that my 
life depended on a strict conformity. Subse- 
quent to this, at intervals, the bleeding still 
continued to return, and by its suddenness 
and quantity had often nearly stopped my 
breathing. I then applied to another of 
the faculty, whose prescriptions gave me 
some relief, but the bleeding still continued 
irresistible


(115)
irresistible, and must have put a period to 
my existence in a few hours, had not Mr. 
Griffin, surgeon, of Chancery-lane, candid- 
ly advised me to have recourse to your 
styptic. 
Before I had used one bottle, this dreadful 
complaint considerably abated, and three 
small phials more has caused the bleeding 
totally to subside, and astonishingly strength- 
ened me. To you, Sir, under God, I am 
indebted for a miraculous prolongation of 
life! 
May you long, very long, live justly ad- 
mired and esteemed, to enjoy the pleasing 
satisfaction of having saved the lives of many 
by your useful discovery. And, may all 
similarly afflicted as I was, be timely led to 
experience the happy effects of your invalu- 
able styptic. I am, and ever shall remain 
with the utmost gratitude, 
Sir, 
Your most devoted humble servant, 
Richard Swayne. 
Bartholomew Ruspini, Esq.
P2 New 

(116)
New York, in the Jerseys, April 10th, 1788. 
To Bar, Ruspini, Esq; 
Sir, 
THOUGH I have not the honour to be 
personally acquainted with you, it would be 
acting the part of an ungrateful man, if I 
was to be silent, in not (next to kind Provi- 
dence) to give you my sincere thanks for 
the attention you have paid to the comfort of 
mankind, in regard of your excellent styptic. 
Unexpressible joy it must be to the heart of 
a man when he is willing to do good, to have 
abilities to perform it: and hard it is for one 
who is willing, and studies how to help his 
fellow creatures in the hour of distress, and 
is unable to do it. I went to Mess. Berry 
and Rogers, and to most of the Physicians in 
New York, and not a drop of your styptic 
could be found in the city: and I had the 
mortification of seeing the patient die; per- 
haps, for want thereof. 
I was taken with bleeding from the nose, 
when four years old, occasioned by a fright 
in my native city of Amsterdam, and have 
ever since been troubled with that disorder,
now 


(117)
now thirty-nine years of age, and have often 
been in a dangerous situation. About two 
years ago I was taken in New York to such 
a degree as baffled the consultations of tnree 
Physicians, who attended me: no restringent 
applications had any effect; till at last I was 
informed by a friend of mine, that a young 
Gentleman, by the name of Ruspini, was 
in town, who had a proper Styptic: I sent 
for a bottle of it, applied it according to di- 
rection, and stopped the bleeding. I had 
some rest, and in the morning getting up the 
bleeding began again; but by its re-applica- 
tion it again stopped it; and I have hardly 
bled since, except by getting great cold or 
stooping, when on application it stops. 
This occasioned an acquaintance with your 
respected son in New York: and I understand 
with pleasure, he is returned, and arrived 
safe in London. 
The different testimonies of the salutary 
effects of your Styptic, of which your son 
gave me a small collection in print, induces
me to beg a favour of you, Sir, hoping you 
will excuse my liberty; and on the due com- 
pliment

(118)
pliment to you by Lord Ferrar’s letter of 
August 13th, 1785, and by your son having 
been in America, is to me a silent demonstra- 
tion that you are a friend to mankind: the 
second bottle of your styptic I bought, I 
kept in my pocket for my own use; besides 
having had the pleasure of serving others,
viz. 
A young woman bleeding dangerous out 
of the nose.—Two small children, twins, 
attacked by the Hooping Cough, and had 
veins broken inward: when I came to the 
house, the one child was dead; and the other 
by inward bleeding, on the point of death;
when I spared two tea spoonsfull out of my 
scanty stock; and the child is alive and well. 
A person who cut his toes off with a broad 
axe, by applying it with lint, stopped the 
bleeding. 
I have the honour to subscribe myself, 
with very sincere regard, 
Sir, 
Your most obedient, 
and most humble servant,
Gg. Swinus Erkelens.

(119)
The following most important case, is that of 
William Crostley, Esq. No. 21,
Paragon Buildings, Bath, who was cured 
by the Styptic Solution, after he had been 
given over by all his physicians: 
In the month of November, 1757, Mr.
Crostley, a gentleman of fortune in Paragon 
Buildings, Bath, subject to a bilious habit,on his 
return from hunting, caught cold; and at 
dinner, had so far lost the use of his hands, as 
to be incapable of helping himself. The Bath 
water, and the prescriptions of his physicians 
at length partially removed the paralysis; but 
soon after this had been done, he was seized 
with an excruciating pain from the stomach
to the back bone, which was then relieved 
by an emetic. On the following Monday (a 
week from the first attack) it returned more 
painfully, and while he was drinking a dish 
of coffee, he suddenly, and most alarmingly 
complained of great sickness, and faintness, 
which was followed by his bringing up near 
TWO QUARTS of coagulated, with some 
fluid blood. To relieve this, his medical at- 
tendants (of which he had many of the most 
eminent in that city) prescribed what they 
thought proper, and amongst other medicines, 
a glister; which when it operated, appeared 
to

(120)
to be loaded with coagulated blood. These 
means procured him a respite until the follow- 
ing Wednesday, when the bleeding returned 
with encreased violence, but was again re- 
strained by the skill of his physicians. 
However, on Sunday the hæmorrhage 
appearing a Third time, all hopes of saving 
his life vanished. To keep him as quiet as 
possible, the bells were ordered not to be 
rung—the city music did not play—and in 
short every attention that his physicians or his 
friends could pay him, was bestowed with a 
liberal hand. In this dreadful state Mr. 
Ruspini’s styptic solution was recommended; 
and as the case was desperate, it was deter- 
mined to try what it could do, though with 
little expectation of success;—however on 
administring a dose as ordered in the printed 
directions, and immediately, under the in- 
spection of his apothecary, Mr. Hay, a very 
prudent and sensible man, its effects were asto- 
nishing; for from that time, the bleeding 
stopped. He continued the styptic every 
twenty minutes, all that day; on the next, 
he did not take it so often; and in a week 
left it entirely off; since which time (near a 
year) he has had no return: his appetite and 
spirits are good, the paralysis of the hands is 
gone,


(121)
gone, and his gratitude, and that of his amiable 
lady, to Mr. Ruspini, brought them to his 
house in Pall-Mall, to relate the foregoing 
miraculous escape, wrought by the styptic 
solution. 
Colchester, Jan. 23, 1789. 
Dear Sir, 
SAMUEL RAND, of the parish of St. 
Peter, Colchester, in the month of January, 
1788, nine days after the attack of a violent 
putrid fever, was seized with a profuse hæ- 
morrhage from the nose. When I was called 
to him, to all appearances he had not lost less 
than a quart of blood. I used the Ag. Styp. 
Pharm. Edin. afterwards filling the nostrils 
with the sycoperdon, which stopped the 
bleeding—The patient was very much re- 
duced by the loss of blood, which from the 
nature and period of his fever, left little hopes 
of his recovery. About six hours afterwards 
I was called to him again, bleeding with equal 
violence. I then, in the presence of Doctor 
Q Wade,

(122)
Wade, and Mr. Cater Day, surgeon, applied 
your Styptic, according to the directions, 
which immediately and effectually stopped the 
hæmorrhage. The patient, though slowly, 
gradually recovered, and has remained per- 
fectly well to this day. I am thoroughly 
satisfied of its superior efficacy in this case, as 
well as in operations where remote vessels are 
frequently and unavoidably divided, many of 
which cannot readily, or at all, be come at 
with the ligature. In all these cases, your 
Styptic can readily be applied with success, 
and with superior advantage to any other, 
being perfectly divested of caustic or irritating 
qualities, and from its ready separation from 
the vessels and contiguous parts, in removing 
the first dressings, which is not always the 
case with the sycoperdon—prepared spunge— 
agaric—lint, &c.—and all the others will en- 
crease inflammation by their irritating qua- 
lities. Mr. Day and myself have frequently 
used your Styptic after operations on the 
smaller vessels, by which the patient has 
been relieved from much pain, and it has al- 
ways succeeded. Last Thursday four vessels 
which must have otherwise been secured by 
ligature, in an amputation of the leg, were 
readily restrained by it, and no hæmorrhage 
has


(123)
has ensued, About ten days ago, I had the 
favour of your’s of the 19th, I received your’s 
of the 25th of December by Capt. Thorley, 
but business and indisposition have prevented 
me answering either, till this day, which I 
hope you will excuse. I intend being in town 
next week, when I shall give myself the 
pleasure of calling on you. Till then, accept 
of my best wishes for the health of Mrs. 
Ruspini and family; in which I am joined by 
my wife, &c. 
I am, Sir, 
Your most humble servant, 
John Wade. 
B. Ruspini, Esq. Pall-Mall. 
Gravesend, Sept. 3, 1787. 
Dear Sir, 
THE following case being a further illus- 
tration of the extraordinary effects of your 
valuable Styptic, I should be wanting of 
gratitude not to communicate its success in 
Q2 this

(124)
this instance. The circumstances were the 
following: 
Wm. Creed, a healthy muscular man, 
about the age of forty, of a plethoric habit of 
body, was chopping some wood with an axe; 
he missed his blow, and the instrument 
divided the anterior tibial artery, at the fore 
part of the ancle joint: from this accident, 
a profuse hæmorrhage ensued, the blood 
issued out to several feet distance. Flour was 
immediately applied, with considerable com- 
pression; but this, they were soon convinced, 
was inadequate to the purpose. A Dutch 
styptic, very high in repute was therefore 
sent for, which was given a very fair trial, 
but the result was unsuccessful. I should 
have observed, that the accident happened 
about seven in the evening, and the applica- 
tion of the various remedies, which were 
suggested, took up more than five hours; 
during which time it was thought he lost 
more than three quarts of blood.—At this 
juncture Mr. Kite was sent for; I attended 
and found the patient extremely faint, but 
the hæmorrhage continued, the blood flow- 
ing with great rapidity; I was aware that 
giving him any cordials would add to encrease 
the

(125)
the action of the vessels, but seeing him in 
that very languid state, I conceived it was ab- 
solutely requisite to administer them; previ- 
ous, to my attempts in stopping the hæmor- 
rhage.—I had your Styptic in my pocket, it 
is true, but in this case, I did not expect it 
could be adequate to the stopping of the 
bleeding; I therefore proposed my needle, 
with a view to take up the artery; but whilst 
I was doing this, I recollected three or four 
cases, which Mr. Kite’s extensive practice 
had presented to me, wherein its success was 
strongly marked, and no blood could be lost 
by the trial, having my needle by me in case 
of failure. My suspicions however were soon
happily relieved, and was soon convinced 
I had no occasion for any thing else, but your 
Styptic; for after I had applied it, according 
to your directions, in five minutes I removed 
my hand, and not a drop of blood issued from 
the wound after; in the course of eight or 
ten days the lint sloughed off, and the wound 
healed in a few weeks. 
This case certainly tells very favorably of 
your Styptic; it may perhaps be surmised by 
some, that from a long hæmorrhage, like 
the case jn point; the extremities, of the ves- 
sels

(126)
sels might be contracted; or that from re- 
peated exposure to the air, the blood might 
coagulate, or what is urged by others, that 
from his great faintness, the arteries might in 
some measure have lost their power of action, 
but clearly it is that neither was the fact, as 
the blood flowed profusely, and with great 
force. In what kind of way it acts, I know 
not; but certain it is, that it contains no 
caustic quality, otherwise not only the sto- 
mach but the facies would detect it. From 
what I have seen of its effects I am inclined 
to think it acts by coagulation; and what 
strengthened my opinion, is, a case I saw in 
your book, where it was administered inter- 
nally, and after the second dose, the patient 
vomited up a quantity of coagulated blood. 
These, Sir, are the particulars of the case, 
and if it will afford you any pleasure, I am 
happy I have taken this method of commu- 
nicating it to you. 
Dear Sir,
Your obedient humble servant, 
Edward Coleman. 
To B. Ruspini, Esq.
Pall-Mall. 

(127)
Writtle, 8th October, 1788. 
My dear Sir, 
I should have been happy to have seen you 
in your way thro' Essex, particularly as I 
have a case under my own inspection and di- 
rection, which may add one more convincing 
proof, to the numberless already adduced 
in your little pamphlet, on the virtues of 
your inestimable Styptic. Happening to 
course during the last season in a deep part 
of the hundreds of Essex, a principal farmer 
at Ruttendon, of the name of Rolph, re- 
quested me to look into his stables where he 
had a very fine young horse that had been 
floundered in the deep lanes; telling me he 
had in vain tried all that the farriers could do, 
and that at present the horse was useless, and 
he feared to loose him. In truth I found the 
poor animal in a shocking situation, the whole 
flank was almost one continued running sore 
(occasioned by the iron traces, in his endea- 
vours to extricate himself) above an inch 
deep; I never saw even a farcy look so angry 
or in a worse state-every method in the com- 
mon course of cleaning, which occurred to 
me, had been tried I found, in vain. Fortu- 
nately I at length recollected your Styptic,
and

(128)
and determined even for the novelty, to try 
its effects. In consequence the farmer called 
on me the next morning—and I gave him a 
quart of the strong vegets mineral water, and 
a half guinea bottle of your Styptic. Accor- 
ding to my directions, he first washed the 
wounds well from the matter, which I feared 
might obstruct the Styptic, with the Goulard, 
and then with a feather dipt in the Styptic, 
touched every part of the wound for ten mi- 
nutes together. I also took one precaution 
which suggested itself to me, to obviate the 
chance of throwing the humours back into 
the blood, which was to put a common rowel 
under the belly. In less than a fortnight, 
having used all the applications, he brought 
the horse to me, and to my great satisfaction 
above half the wounds were totally healed, 
the rest look’d in a fair way, and the horse 
had been again to his accustomed work. I 
gave him another bottle of Styptic, and the 
Goulard as before, and the man with gratitude 
acknowledges a perfect cure. I have been 
thus prolix for the satisfaction of your friends. 
As the case is, I believe, entirely new. 
I am with truth and regard, 
Dear Sir, 
Your sincere well wisher, &c. 
Wm. H. G. Birch. 


(129)
Sir, 
MY Nose began to bleed on Sunday the 
sixth day of July, in the afternoon, and then 
again in the evening, a little; about three 
o’clock on Monday morning it began again, 
and did not cease, till I fainted for loss of 
blood; it served me so for two or three times. 
I went to a chemist and he gave me some- 
thing, and recommended me to be cupp’d, 
which I was on Tuesday; but this evening, 
after supper, it burst out again; then I went 
to the Apothecary, and it stopped till next 
day, when it bled as much as ever. I then 
sent for a surgeon, who bled me again, and 
plugged up my nostrils. We were sure that 
I lost more than five quarts of blood. I had 
no return till this day three weeks, when 
I went to the surgeon twice, who said 
he could not answer for its bleeding again. 
I was so weak and faint, that I enquired of 
the chemist, about Mr. Ruspini’s Styptic, 
who advised me to try it, and said it had done 
amazing wonders, so that I set about it di-  
rectly, (and with the blessing of God,) and
Mr. Ruspini’s assistance, in syringing his 
R Styptic


(130)
Styptic up my nostril, though the blood was 
flowing very fast, yet it stopt it in an 
instant, and I have never had any return of it 
since. 
Yours, much obliged,
Robert Pickett, 
Cheesemonger, Chancery-lane.
March 10, 1789. 
East Grinstead, Jan. 7, 1789. 
Sir, 
ACCORDING to my promise, made 
in a letter I sent you some time ago, I have 
taken up my pen to give you a second in- 
stance of the effect of your very valuable 
Styptic, which has occurred in this town; 
and though it had not the immediate effect of 
stopping the hæmorrhage; as in the first 
case I sent you, yet it effected it in the 
course of a few minutes. The case is as fol- 
lows:
The

(131)
The coachman of J. Staples, Esq. of this 
town, in attempting to shoot some birds in 
his master’s yard (and having a gun which 
had been charged for some considerable time) 
had the misfortune, in firing it off, to have 
it burst in his hand; the consequence of 
which was almost a total separation of the 
thumb from the hand, it adhering only 
slightly at the upper part; a very violent 
effusion of blood followed, which was re- 
strained in a great measure by the application 
of the common styptics, with lint, &c. 
The accident happened in the morning, and 
in the evening the symptomatic fever coming 
on, occasioned the vessels to bleed again very 
profusely, and the man finding himself 
much weakened, from the blood, it was 
thought proper to take off the bandages, and 
to try the effect of your Styptic; it was ap- 
plied, agreeable to your directions on lint, 
though little or no degree of pressure was 
made use of, and in a very short space of 
time, the hæmorrhage stopped; the applica- 
tion of the Styptic (it may be necessary to 
observe) did not occasion any pain, and the 
man’s hand suppurated kindly, and with care 
got well soon. 
R2 I have

(132)
I have likewise tried it in two or three 
cases where venesection was performed, 
and a large orifice made purposely, by apply- 
ing a bit of lint moistened with the Styptic, 
and after letting it remain on the orifice for 
about a minute, have removed it entirely, 
and made the patients shut their hands, and 
grasp any thing very forcibly, and no hæmor- 
rhage ensued; nor could they produce a 
return of it with any degree of motion they 
could make with the arm. 
Should any further opportunity offer of 
trying it, I shall be happy in communicating 
every instance of its success. 
I am Sir, 
Your humble servant, 
Rob. Hilton. 
Mr. Tweed’s compliments to Mr. Rus- 
pini; begs leave to send him the following 
case, as it proves the efficacy of his Styptic; 
hopes

(133)
hopes a sufficient apology for addressing him 
unknown. 
SARAH PARKER, aged 19, consulted 
me about a tumour in her neck and face, 
which had been gradually increasing for five 
years. I recommended extirpation as the only 
remedy; which was agreed to, and perfor- 
med last Monday. In the operation, the 
facial artery (which was much enlarged to 
nourish the steatoma which weighed upwards 
of four ounces) was divided, and consequent- 
ly a violent hæmorrhage, which was suppres- 
sed by the hand of an assistant, till I had quite 
removed the tumour, which adhered very 
closely to the integuments, &c. I then mois- 
tened a small piece of lint with your Styptic 
and applied to the vessel; the bleeding imme-
diately stopped, without compress or bandage,
was dressed up superficially, and the wound 
this morning appeared in a healthy state. 
Your's, 
R. Tweed.
Sunday Evening, 
Nov. 9, 1788. 
Chelmsford. 

(134)
To B. Ruspini, Esq. London.
Sir, 
SOME short time ago, I cropt the ears 
of my horse, and I applied the actual cautery 
to stop the hæmorrhage; but in the course of 
the night, the bleeding returned, and various 
applications were made use of without effect.
I at last applied your most excellent Styptic, 
and although the hæmorrhage was very pro-
fuse, insomuch that I thought the horse 
would have died, it immediately stopped it, 
and there was no more return of the bleed- 
ing. The mode of using your Styptic was 
this:—I poured about a small tea-spoonful 
of it into an oyster shell, and with a little lint, 
I washed the ears. 
I have thought proper to mention the suc- 
cess of your Styptic in the above case, as a 
hint to horse-keepers, but particularly to 
Farriers: and I am sure your humanity, and 
the true sense you have of the usefulness of 
that noble animal, the horse, will not require 
an apology for the trouble I have given you.
I am

(135)
I am wishing you to make use of this letter 
in any way you please. 
Sir, 
Your very humble servant, 
Raymond. 
Dec. 11, 1788. 
Belchamp-Hall, 
near Sudbury, Suffolk. 
The following are the outlines of the case of 
Mr. THOMPSON, an eminent hosier in 
Newgate-street. If any person should be 
desirous of the particulars of this important 
case, Mr. Thompson has kindly requested 
Mr. Ruspini to refer them to him: 
HE was seized with a violent hæmorrhage, 
for which he had the best advice; but in 
spite of the most judicious efforts, the bleeding 
still continuing, he was desired to take Mr. 
Ruspini's Styptic Solution, which imme- 
diately stopped it; and on taking seven or 
eight large bottles, his health was completely 
restored. 
CANCER

(136)
CANCER in the THIGH. 
ELIZABETH TICKENS, Hungerford- 
stairs, hath been for many years afflicted with 
a large cancerous tumour in her thigh, which 
bleeding profusely at different periods, had 
reduced her to a state of great weakness. 
She having used many different prescriptions 
for the restraining of the hæmorrhage, without 
effect, was, by the advice of Mr. Spalding, 
an ingenious surgeon, in the service of the 
honourable East India Company, induced to 
try Mr. Ruspini's Styptic, to which she owes 
her present health and ease, as it hath never 
failed to stop the bleeding in one instance.
IT 

(137)
IT may seem unnecessary to adduce any 
further instances of the happy effects of Mr. 
Ruspini's Styptic Solution; but the following 
extract of a case, sent to Mr. Ruspini, by an 
eminent man-midwife, should be inserted, 
for the benefit of such of the fair sex as may 
labour under the same, but too common 
disease: 
A young unmarried lady, aged 18, was 
seized with a most dangerous hæmorrhage 
from the uterus, which continuing three 
weeks, reduced her to the brink of the grave. 
The Styptic Solution was administered both 
externally and internally: in two days the 
bleeding stopped, and she remains in good 
health. 
S

DIRECTIONS 
FOR USING THE 
STYPTIC SOLUTION. 
TAKE a sufficient quantity of lint to cover the wound: 
let it be well soaked in the Solution; then put it on the 
part, first cleansed as much as possible from the blood, or the 
Styptic will be washed off, and it cannot produce so good an 
effect; then let it be kept there for short time, by pressing it 
lightly with the fingers, or the hand. Should the wound 
bleed afresh, the application is to be renewed, with the same 
caution, and retained by the moderate pressure of a linen 
roller. 
In bleedings from the nose, a small piece of lint, being dip- 
ped into the Styptic, is to be pushed up the nostril, and if the 
bleeding does not immediately cease, a small quantity of the
Solution is to be injected with a syringe. 
Styptics in general are made of corrosive materials, which 
cannot be taken inwardly without injury to the mouth or 
stomach; on the contrary, Mr. Ruspini's Styptic may be 
taken without injury to either. In external wounds, it gives 
no pain, in internal, it excites no disagreeable sensations; but 
has most wonderfully cured internal bleedings, it appearing 
upon record indisputably attested, in the accounts which Mr. 
Ruspini has been authorised to publish, and recently in the 
case of a lady of a most tender constitution, who in a 
violent spitting of blood, has not only been relieved, but com- 
pleted cured, after having used six bottles of the Styptic Soluti- 
on, without any other mixture. A proof that it is perfectly 
harmless in its nature. 
In a violent uterine flooding, the Styptic may be used with 
the utmost safety, as an injection, which may be repeated, ac- 
cording to the urgency of the case. In bloody stools, a cele-
brated 

(139)
brated physician asserts that it has given great relief to the pati- 
ent by mixing it in clysters. 
THE MODE OF ADMINISTERING. 
THE patient should take a tea spoonful for a dose, in red 
rose, green tea, or alone as much as a table spoonful, without 
the least danger; and this may be repeated as often as the 
urgency of the case requires. 
Mr. Ruspini flatters himself, that if the Styptic is properly 
and really applied to the surface of the wound, and not too 
much mixed with the flowing blood, it will always produce the 
most speedy and salutary effects. 
The above Styptic, in bottles of eleven shillings and six- 
pence, and one pound two shillings each, stamp duty included, 
to be had only at Mr RUSPINI'S, surgeon-dentist to his Royal 
Highness the Prince of Wales, in Pall-Mall; Mr. PRICE, 
Leadenhall-street; Mr. GOLDING, Cornhill; Mr. TASSE- 
MAN, York; Mr. RAEBOURN, Edinburgh; Messrs. 
Gibson and Co. Newcastle upon Tyne; Mr. Buckland, 
Druggist, Portsmouth; Mr. Morley, Doncaster; Mr. Peck, 
Druggist, Chelmsford; Mr. Kaymer, Colchester; Mr. 
Shircliff, Bristol; Mr Cook, Shrewsbury; Mr. Swinney, 
Birmingham; Mr. Barker, Derby.