^;L if* Jl :..-:.-**^ ^ v *. ,>\ - .>i>..»j,'1' * # * :&•#* ■/ % &' ■'?»* £-^ ;.v.\* "jgfcS NATIONAL LIBRARY OF MEDICINE Bethesda, Maryland Mf&VtfUj?r+*5 u THE PRINCIPLES MIDWIFERY; INCLUDING TOE DISEASES WOMEN AND CHILDREN. BY JOHN BURNS, M. D. LECTURER OK MIDWIFERY, AVD MEMBER OF THE FACULTY OF PHYSICIANS AND SURGEONS, GLASGOW. THE FOURTH AMERICAN, FROM THE THIRD LONDON EDITION, GREATLY ENLARGED. WITH IMPROVEMENTS AND NOTES, BY THOMAS C. JAMES, M. D. professor of midwifery is the university of Pennsylvania. VOL. I. k PHILADELPHIA: PUBLISHED BY BENJAMIN WAfclTER, EDWARD & RICHARD PARKER, MATIIKW CARE If & SON, BENJAMIN & THOMAS KITE, SOLOMON W. CONRAD, ANTHONY FINLKt,\AM> MOSES THOMAS. J. R. A*Skeyrett, Printer. 1817. 003 B33 DISTRICT OF PENNSYLVANIA, TO WIT: Be it remembered, That on the seventh day of September, in the thirty-eighth year of the Independence of the United States of America, A. D. 1813, Benjamin and Thomas Kite, Johnson and Warner, Edward Parker, Kimber and Conrad, Mathew Carey, Moses Thomas, Anthony Finley, and Redwood Fisher, of the said District, have deposited in this office the title of a Book, the right whereof they claim as Proprie- tors, in the words following, to wit: " The Principles ofMidwifery; including the diseases of Women and " Children. By John Burns, Lecturer on Midwifery, and Member of " the faculty of Physicians and Surgeons, Glasgow. The third Ameri- " can, from the second London Edition, much enlarged. With Improve- " ments andJVotes, by Thomas C. James, M. D. Professor of Midwifery "in the University of Pennsylvania." In conformity to the Act of the Congress ofthe United States, intituled, " An Act for the Encouragement of Learning, by securing the Copies of Maps, Charts and Books, to the Authors and Proprietors of such copies during the times therein mentioned."—And also to the Act, en- titled, " An Act supplementary to an Act, entitled' An Act for the En- couragement of Learning, by securing the Copies of Maps, Charts and Books, to the Authors and Proprietors of such copies during the times therein mentioned,' and extending the benefits thereof to the Arts of designing, engraving, and etching historical and other Prints." D. CALDWELL, Clerk of the District of Pennsylvania. 6 76/ /3~fi(o-Vt PREFACE OF THE AUTHOR. IN preparing this work, I have endeavoured to pro- ceed as much as possible upon the method of induction. I have collected with care the different cases which have been made public, as well as my own private ob- servations. To these I have added the opinions and advices given by others, in so far as they seemed to be founded on facts, and supported by experience. From the whole I have deduced, in the different parts of my subject, both the symptoms and the practice. The anatomical descriptions, I have given from dis- sections and preparations before me whilst writing. I intended to have added to the text, copious re- ferences to the opinions and cases contained in systems, or scattered through other publications. This would have rendered the present book, in some manner, an index to those already published, and been of con- siderable service to practitioners, who wished to con- sult them upon any particular point. But in spite of all my endeavours, this work has extended to a length which rendered it necessary to strike out many re- ferences, and shorten the account of cases, to prevent it from swelling to a size which would have rendered it less generally useful. Whilst I thus state the plan on which I have pro- ceeded, I acknowledge myself deeply sensible, that its execution does not bear any proportion to the impor- IV tance of the subject. Should this work fall only into the hands of those, competent to judge on their profes- sion, it would, if faulty or deficient, do little harm : but should it ever be circulated more extensively, it must like other systems and elements, have an in- fluence on the opinions and future practice of the stu- dent of midwifery; and will prove useful or injurious to society, according to the correctness of the principles it contains. When I consider how important the dis- eases of women and children are, and how much de- pends on the prudent management of parturition, I feel the high responsibility which falls on those who pre- sume to give lessons in midwifery. I do, however, sincerely trust, that the precepts I have inculcated will, in general, be found agreeable to the experience and practice of our best teachers ; and, on a review of the whole, I cannot say that I have either wasted the reader's time in idle theory, or misled his opinion by mere speculation. In preparing a third edition for the press, I have carefully revised the whole work, and have made many additions, which I hope will prove useful. Glasgow. October. 1814. PREFACE OF THE EDITOR. IT is not the intention of the present editor to incur the fault so sharply reprehended by Johnson, and "re- tard the instruction" contained in the ensuing volumes, by an unnecessary and prolix preface. He will only briefly mention, that our author, " equally experienced as a teacher and practitioner," has, from the acknow- ledgement of the most competent judges,* "by a judi- cious arrangement, by a faithful exposition of facts and observations, and by a methodical induction of the prin- ciples and practice of the art, accomplished in this work all that could be expected, in the present state of the science, to give a new interest to the subject. " The prominent advantage, that confers upon it a decided preference to all others, as a System or Class- book, is, that every subject, directly or indirectly con- nected with the practice of the accoucheur, is here brought into one connected view. " But what we are most disposed to recommend in this volume,! is the pathological department, and the descriptions and treatment of the diseases of puerperal women, and of children. A more copious, scientific, and judicious account of these diseases, is perhaps no where to be met with." Thus far the editors of the Edinburgh Medical and Surgical Journal. • Edin. Med. and Surg. Journal, for 1810. f The work was originally published in one volume. VI One great advantage of this work to the student soli- citous of full and accurate information on the subjects of which it treats, is to be experienced in the very valu- able notes and references of the author, to almost all that has been communicated by practitioners of deserv- ed celebrity, on parallel subjects or cases. In this point of view, it may be considered as the Common- place Book of an immense fund of the most useful practical knowledge, indispensable as a guide to the in- experience of the student, and earlier practitioner, and of no ordinary utility and aid, to the maturer acquire- ments of advanced and established professional skill. This edition has been considerably enlarged and im- proved by the author. The sections on abortion and uterine hemorrhage, will be found to have been very considerably extended, and rendered of far greater va- lue •—indeed, they may now be considered, as contain- ing the essence of his separate Treatises on those very interesting subjects, which have for some time enjoyed the approbation of the public. The new articles, totally omitted in the former edi- tion, but by the author introduced into this, are those on pneumonia, on ephemeral fever, on weed or intesti- nal fever, and on diarrhoea, as existing in the puerpe- ral state, and on chorea, on bronchitis, and on peri- tonitis, as the diseases of the infantile age. These, it is presumed, will not fail to give additional interest to the work. The editor has taken the liberty of introducing into the text, a section on the difference between the male and female pelvis; which as he conceived, the author ought not to have omitted; and Dr. Clarke's account of the cauliflower excrescence of the os uteri. Whether Vll this is only a variety of the spongoid tumour, he will leave to the reader to decide. It appears to assume some difference in its form and train of symptoms. The history is from the pen of an accurate observer of na- ture, and a judicious and experienced practitioner. As Baudelocque has explained the mechanism of parturition, more fully and minutely than almost any other writer, and as his work on midwifery has obtain- ed considerable reputation with the medical public of the United States, it has been judged proper, occasion- ally, to give a general view of his divisions of labour, together with the several species of presentations, which it may be useful to keep in recollection in actual practice. Some tables, relative to this part of our sub- ject, from the last edition of his valuable work that have not, as far as we know, been hitherto translated, will also be given in the appendix. These, it is hoped, will not be entirely devoid of interest, either to the stu- dent or practitioner. The chief mass of the notes in Dr. Chapman's edi- tion of our author s production, have been, by permis- sion retained in this ; these are marked with the letter C. The notes added by the present editor have alpha- betical references, and are thus sufficiently distinguish- ed from those of the author, and of the intelligent editor of whose information we have availed ourselves, and to whom we have just alluded. These will be found to be altogether of a practical nature, and are intended solely to explain, or illustrate the text; as it has been found rarely necessary to differ in sentiment from one. whose opinions seem generally to be founded on the solid basis of practical truth. Auy additions made to the text, or Author's notes, are included between brackets. Vlll The Author has rendered this last edition more in- teresting, by some valuable additional matter, and the Editor has subjoined a few notes, which he hopes will not be found entirely nugatory. Philadelphia, July 1st, 1817. CONTENTS. BOOK I. Of the Structure, Functions, and Diseases of the Pelvia and Uterine System, in the unimpregnated state, and during Gestation. CHAPTER I. Of the Bones of the Pelvis. Section 1. General view ... Page 1 Section 2. Ossa innominata ... 2 Section 3. Sacrum and coccyx - 5 CHAPTER II. Of the Articulation of the Bones of the Pelvis, and their occa- sional separation. Section 1. Of the symphysis pubis ... f Section 2. Sacro-iliac junction - - - 8 Section 3. Vertebral junction, and obliquity of the pelvis......-9 Section 4. Separation of the bones - 9 Section 5. Difference of female from male pelvis 14 CHAPTER III. Of the soft parts which line the Pelvis. Section 1. Muscles.....16 Section 2. Arteries......17 Section 3. Nerves.....18 \$*Section 4. Lymphatics.....19 X CHAPTER IV. Of the Dimensions of the Pelvis. Section 1. Brim and outlet - - - Page 20 Section 2. Cavity.....21 Section 3. Pelvis above the brim - - - 23 Section 4. Axis of the brim and outlet - 24 CHAPTER V. Of the Head of the Child, and its progress through the Pelvis in Labour. Section 1. Bones of the head - 24 Section 2. Size of the head .... 26 Section 3. Passage of the head - 27 CHAPTER VI. Of Diminished Capacity and Deformity of the Pelvis. Section 1. Deformity from rickets - - 29 Section 2. Deformity from malacosteon - 31 Section 3. Deformity from exostosis and tumours 33 Section 4. Means of ascertaining the dimensions and size of the head when broken down - 35- CHAPTER VII. Of Augmented Capacity of the Pelvis, 36 CHAPTER VIII. Of tlie external Organs of Generation. Section 1. General view - 37 Section 2. Labia and nymphw ... 38 Section 3. Clitoris.....38 Section 4. Urethra .... 39 Section 5. Orifice of vagina and hymen - 41 CHAPTER IX. Of the Internal Organs of Generation. Section 1. Vagina..... 42 XI Section 2. Uterus and its appendages - Page 43 CHAPTER X. Of the Diseases of the Organs of Generation. Section 1. Abscess in the labium - - 47 Section 2. Ulceration of the labia - - 48 Section 3. Excrescences on the labia - 51 Section 4. Scirrhous tumours - - 51 Section 5. Polypous tumours - - 52 Section 6. OSdema - - - 53 Section 7. Hernia, laceration, &c. - - 53 Section 8. Diseases of the nymphse - 54 Section 9. Diseases of the clitoris - - 55 Section 10. Diseases of the hymen - - 56 Section 11. Laceration of the perinseum - 57 Section 12. Imperfection of the vagina - 59 Section 13. Inflammation and gangrene of the vagina - - - - - 59 Section 14. Induration, ulceration, and polypi 60 Section 15. Inversion . - - 60 Section 16. Watery tumour - - - 61 Section 17. Hernia - - - ... 61 Section 18. Encysted tumour and varices - 62 Section 19. Spongoid tumour - - 63 Section 20. Erysipelatous inflammation - 63 Section 21. Fluor albus . - - 65 Section 22. Affections of the bladder - - 70 Section 23. Excrescences in the urethra - 74 Section 24. Deficiency and inal-formation of uterus 76 Section 25. Hysteritis . - - 77 Section 26. Ulceration of the uterus - - 78 Section 27. Scirro-cancer - - - 80 Section 28. Tubercles - - - - 84 Section 29. Spongoid tumour - - 86 Section 30. Cauliflower excrescence from oa uteri 87 Section 31. Calculi . - - 89 Section 32. Polypi - - - - 90 Section 33. Malignant polypi - - 95 vol. i. 2 A XII Section 34. Moles - - - Page 96 Section 35. Hydatids - ' - - 97< Section 36. Aqueous secretion - - 99 Section 37. Worms - - - 10° Section 38. Tympanites - 10° Section 39. Prolapsus uteri - - 101 Section 40. Hernia - '- - - 107 Section 41. Dropsy of the ovarium - 108 Section 42. Other diseases of the ovarium - 114 Section 43. Deficiency - - - 115 Section 44. Diseases of the tubes and ligaments 115 CHAPTER XI. Of Menstruation, - 116 CHAPTER XII. Of Diseased States of the Menstrual Action. Section 1. Amenorrhea ... 121 Section 2. Formation of an organized substance 129 Section 3. Dysmenorrhoea - - 129 Section 4. Copious Menstruation - - 131 Section 5. Menorrhagia - - - 131 CHAPTER XIII. Of the Cessation of the Menses, - 137 CHAPTER XIV. Of Conception, and the term of Gestation, - 139 CHAPTER XV. Of the Gravid Uterus. Section 1. Size and position - - 143 Section 2. Developement of the uterus, and state of its cervix - 144 Section 3. Muscular fibres - - 145 Section 4. Ligaments - 146 Section 5. Vessels - 147 S otion 6. Of the foetus - - - 148 Section 7. Its peculiarities - - 153 Mil. Section 8. Umbilical cord Section 9. Placenta Section 10. Membranes and liquor amnii Section 11. Decidua ... CHAPTER XVI. Of Sterility, CHAPTER XVII. Of Extra-uterine Pregnancy. Section 1. Symptoms, progress, and species Section 2. Treatment CHAPTER XVIII. Of the Signs of Pregnancy. CHAPTER XIX. Of the Diseases of Pregnant Women. Section 1. General effects - - - 177 Section 2. Febrile state - - - 179 Section 3. Vomiting - - - - 181 Section 4. Heartburn - - - 183 Section 5. Fastidious taste - - - 183 Section 6. Spasnj of stomach and duodenum 184 Section 7. Costiveness - - - 184 Section 8. Diarrhoea - - - 186 Section 9. Piles - - - - 187 Section 10. Affections of the bladder - 188 Section 11. Jaundice - - - 190 Section 12. Coloured spots - - 190 Section 13. Palpitation - - - 190 Section 14. Syncope - - - 191 Section 15. Dyspnoea and cough - - 192 Section 16. Hemoptysis and haematemesis - 193 Section 17. Head-ache and convulsions - 193 Section 18. Tooth-ache - - 195 Section 19. Salivation - - - 195 Section 20. Mastodynia - - - 196 Page 157 160 163 164 166 168 172 17 XIV Section 21. ffidema - - Page 196 Section 22. Ascites - - - 197 Section 23. Redundance of liquor amnii - 199 Section 24. Watery discharge - - 201 Section 25. Varicose veins - - 20S Section 26. Muscular pain - - 203 Section 27. Spasm of ureter - - 204 Section 28. Cramp - 204 Section 29. Distension of the abdomen - 204 Section 30. Hernia ... 205 Section 31. Despondency - - - 206 Section 32. Retroversion of uterus - 206 Section 33. Antiversion - - - 213 Section 34. Rupture of uterus - - 214 Section 35. Abortion, and treatment of pregnant women - 217 Section 36. Uterine hemorrhage - - 255 Section 37. False pains - - 298 Notes - - . . . 501 THE PRINCIPLES OF MIDWIFERY.- BOOK I. OF THE STRUCTURE, FUNCTIONS, AND DISEASES OF THE PELVIS AND UTERINE SYSTEM, IN THE UNIMPREGNATED STATE, AND DURING GESTATION. CHAP. I. Of the Bones of the Pelvis. § I. GENERAL VIEW. . -•■ * THE practical precepts, and rules in Midwifery, are easily understood, and readily acquired. They arise evident- ly from the structui'e and actions of the parts concerned in parturition; and whoever is well acquainted with this struc- ture and these actions, may, from such knowledge, deduce all the valuable and important directions which constitute the Practice of Midwifery. One of the first, and not the least important, of the parts concerned in parturition, is the pelvis, which must be exa- mined, not only on account of its connection with the uterus and vagina, but also of its own immediate relation to the de- livery of the child, and the obstacles which, in many instances, it opposes to its passage. VOL. I. B 2 The pelvis consists, in the full grown female, of three large bones, two of which are very irregular, having no near resemblance to any other object,- on which account they have been called the ossa innominata. These form the sides and front of the bason or pelvis. The back part consists of a triangular bone, called the os sacrum, to the inferior extremi- ty or apex of which, is attached, by a moveable articulation, a small bone, which, from its supposed resemblance to the beak of a cuckoo, has been named the os coccygis. The os innominatum, in infancy, consists of three separate pieces: the upper portion is called the ilium, or haunclfbone; the under, the ischium, or seat bone; and the anterior, which is the smallest of the three, is called the os pubis, or share bone. These all join togetlier in the acetabulum, or socket, formed for receiving the os femoris, and are connected by a very firm gristle or cartilage. This, before the age of pu- berty, is converted into bone, so that the three different pieces are consolidated into one, though the names given to the bones originally are still applied to the different parts of the united os innominatum. The sacrum also, which seems to consist only of one curv- ed triangular bone, is really made up of several pieces, which, in the child, are nearly as distinct as the vertebrae, to which, indeed, they bear such a resemblance, that they have been considered as a continuation of them; but from their imperfect structure, and subsequent union, they have been called the false vertebrae. The bones of the pelvis are firmly joined together, by means of ligaments and intermediate cartilages, and form a very irregular canal, the different parts of which must be briefly mentioned. § 2. OSSA INNOMINATA. When we look at the pelvis, we observe, that the ossa innominata naturally divide themselves into two parts, the up- permost of which is thin and expanded, iiTegularly convex on its dorsum or outer surface, hollow on the inside, which 3 is called the costa, and bounded by a broad margin, extend- ing in a semicircular direction from before backwards, which is called the crest of the ilium. The under part of the os in- nominatum is very irregular, and forms, with the sacrum, the cavity of the pelvis. The upper expanded part has little influence on labour, and serves, principally, for affording attachment to muscles. In the under part, we have several points to attend to. 1st. The upper and under parts form an angle with each other, marked by a smooth line, which is a continuation of the margin of the pubis, or anterior part of the bone. It extends from the symphysis pubis, all the way to the junc- tion of the os innominatum with the sacrum, and is called the linea iliopectinea. It is quite smooth and obtuse at the sides, where the two portions form an angle; but at the anterior part, where the upper portion is wanting, it is sharp, and sometimes is elevated into a thin spine like the blade of a knife. 2d. The upper portion is discontinued exactly about the middle of this line, or just over the acetabulum; and at the termination, there is from this portion an obtuse projection overhanging the acetabulum, which is called the inferior spinous process of the ilium, to distinguish it from a similar projection about half an inch higher, called the superior spine. 3d. The under part of the bone is of the greatest import- ance, and in it we recognise the following circumstances. Its middle is large, and forms on the outside a deep cup or acetabulum, for the reception of the head of the thigh bone. On the inside, and just behind this cup, it forms a smooth polished plate of bone within the cavity of the pelvis, which is placed obliquely with regard to the pubis, and has a gen- tle slope forward. The cone of the child's head, in labour, moves downwards, and somewhat forwards, on this, as on an inclined plane; it may be called the plane of the ischium, although a part of it be formed by the ilium. 4th. Standing off from the back part of this, about two inches beneath the linea iliopectinea, is a short projection, 4 called the spine of the ischium, which seems to encroach a little on the cavity of the pelvis, and is placed, with regard to the pubis, still more obliquely than the plane of the is- chium. It must, consequently, tend to direct the vertex, as it descends, still more towards the pubis. 5th. Beneath this, the ischium becomes narrower, but not thinner; on the contrary, it is rather thicker, and terminates in a rough bump, called, the tuberosity of the ischium. 6th. Next, we look at the anterior part of the bone, and find, that just before the plane of the ischium, there is a large hole in the os innominatum. This is somewhat oval in its shape; and at the upper part within the pelvis, there is a depression in the bone, which, if followed by the finger or a probe, leads to the face of the pelvis. The hole is called the foramen thyroideum. 7th. Before this hole the two ossa innominata join, but form with each other on the inside, a very obtuse angle, or a kind of smooth rounded surface, on which the bladder partly rests. The .junction is called the symphysis of the pubis. t 8th. The, two bones, where they form the symphysis, are Joined with each other for about an inch and a half; then they divaricate, forming an angle, the limbs of which ex- tend all the way to the tuberosity of the ischium. This se- paration or divarication is called the arch of the pubis, which is principally constructed of the anterior boundary of the foramen thyroideum, consisting of a column or piece of bone, about half an inch broad, and one-fourth of an inch thick, formed by the union of the ramus of the pubis, and that of the ischium. 9th. At the upper part of the symphysis, or a very little from it, the os innominatum has a short obtuse projection, called the crest of the pubis, into which Poupart's ligament is inserted; and from this there runs down obliquely, a ridge on the outside of the hone, which reaches all the way to the acetabulum, and overhangs the foramen thyroideum. 10th. When we return to the back part of the os innomi- natum, we find, that just after it has formed the plane of the 5 ischium, it extends backwards to join the sacrum; but in do- ing so, it forms a very considerable notch or curve, the con- cavity of which looks downwards. When" the sacrum is joined to the bone, this notch is much more distinct. It is called the sacro-sciatic notch or arch : for one side is formed by the ischium, and is about two inches long; the other is formed chiefly by the sacrum, and is about half an inch longer. In the recent subject, strong ligaments are extended at the under part, from the one bone to the other, so that this notch is converted into a regular oval hole. 1 lth. Lastly, this notch being formed, the bone expands backwards, forming a very irregular surface for articulation with the sacrum ; and the bones being joined, we find that the os innominatum forms a strong, thick, projecting ridge, ex- tending farther back than the spinous processes of the sa- crum. This ridge is about two inches and three quarters long, and is a continuation of the crest of the ilium, but is turned downwards; whereas were the crest continued in its former course, it would meet with the one from the opposite side, behind the top of the sacrum, forming thus a neat semi- circle; but this ridge, if prolonged on both sides^ would form an acute angle, the point of junction being opposite the bot- tom of the sacrum. From this strong ligaments pass" to the sacrum, to join, the two bones. § 3. SACRUM AND COCCYX. The sacrum forms the back part of the pelvis. It is a triangular bone, and gently curved; so that, whilst a line drawn from the one extremity to the other, measures, if it subtend the arch, about four inches; it will, if carried along the surface of the bone, measure full half an inch more. The distance betwixt the first or straight line, and the middle of the sacrum is about one inch. The breadth of the base of the sacrum, considered as an angular body, is full four inches : the centre of this base is shaped like the surface of the body of one of the lumbar vertebrae, with the last of which it joins, forming, however, an angle with it, called the G great angle, or promontory of the sacrum.(a) From this the bone is gently curved outward on each side, toward the sacro- iliac junction, contributing to the formation of the brim of the pelvis. The upper half of the side of the bone is broad and irre- gular for articulation with the os innominatum. The ante- rior surface of the bone is smooth and concave; but often we observe transverse ridges, marking the original separation of the bones of the sacrum. Four pair of holes are found dis- posed in two longitudinal rows on the face of the sacrum, communicating with the canal which receives the continua- tion of the spinal marrow; through these the sacral nerves issue. These holes slope a little outward, and betwixt the two rows is the attachment of the rectum. The posterior surface of the bone is very irregular; and, we observe, 1st, The canal extending down the bone, for receiving the con- tinuation of the spinal marrow. 2d. At the upper part of this are two strong oblique processes, which join with those of the last lumbar vertebra. 3d. On a central line down the back of the canal, there is an irregular ridge analogous to the spines of the vertebrae. 4th. The rest of the surface is very irregular and rough; and we observe, corresponding to the holes for transmitting the sacral nerves on the exterior surface, the same number of foramina on this posterior sur- face, but, in the recent subject, they are covered with mem- brane, leaving o»ly a small opening for the exit of nervous twigs. The coccyx is an appendage to the sacrum, and as it is in- clined forwards, from that bone, the point of junction has been called the little angle of the sacrum. It is, at first, al- together cartilaginous, and cylindrical in its shape, but it gradually ossifies and becomes flatter, especially at the up- per part, which has been called its shoulder. In men it is generiilly anchylosed with the sacrum, or at least moves with difficulty, but it almost always separates by maceration. In Women it remains mobile, and, during labour, is pressed back (a) But more commonly the projection of the sacrum. 7 so as to enlarge the outlet of the pelvis. By falls or blows it may be luxated; and if this be not discovered, and the bone replaced, suppuration takes place about the rectum, and the bone is discharged. CHAP. II. Of the Articulation of live Bones of the Pelvis, and their occa- sional separation. § 1. OF THE SYMPHYSIS PUBIS. The bones of the pelvis are connected to each other, by intermediate cartilages, and by very strong ligaments. The ossa innominata are united to each other at the pubis, in a very strong and peculiar manner. It was supposed that they were joined together by one intermediate cartilage; but Dr. Hunter* was, from his observations, led to conclude, that each bone was first of all covered at its extremity with carti- lage, and then betwixt the two was interposed a medium, like the intervertebral substance, which united them. This sub- stance consists of fibres disposed in a transverse direction. M. Tenonf has lately published an account of this articu- lation ; and is of opinion, that sometimes the one mode and sometimes the other obtains. I am inclined to think, that Dr. Hunter's description is applicable to the most natural state of the part; but we often, in females^nd that the in- termediate fibrous substance, especially at the posterior part, is absorbed, and its place supplied with a more fluid sub- stance ; or, on the contrary, anchylosis may sometimes take place; a circumstance which Dr. Hunter says he never saw, but which I have met with. Besides this mode of connec- tion, there is also in addition a very strong capsule to the articulation, the symphysis being covered on every side with • Vide Med. Obs. and Inq. Vol. II. p. 333. 7 Vide Mem. de PInslitutdes Sciences, Tome VI. p. 1T2. 8 ligamentous fibres, which contribute greatly to the strength of the parts. § 2. SACRO-ILIAC JUNCTION. The ossa innominata are joined to the sacrum bj means of a thin layer of cartilaginous substance, which covers. each bone; that belonging to the sacrum is the thickest: both are rough, and betwixt them is found a soft yellowish substance in small quantity. The connection of the two bones therefore, so far as it depends on this medium, cannot be very strong; but it is exceedingly strengthened by liga- mentous fibres, which serve as a capsule; and behind, several strong bands pass from the ridge of the ilium to the back of the sacrum; sometimes the/bones are united by an- chylosis. At the lower part, additional strength is obtained by two large and strong ligaments, which pass from the ischium to the sacrum, and therefore are called the sacro- sciatic ligaments. The innermost of these arises from the spine of the ischium, is very strong, but at first not above a quarter of an inch broad; it gradually expands, however, becoming at its insertion about an inch and a quarter in breadth. It passes on to the sacrum, and is implanted into the lower part of the side of that bone, and the upper part of the " coccyx. It converts the sacro-sciatic notch into a regular oval hole, the inferior end of which, owing to the neat expansion of the ligament, is as round and exact as the upper. As it makes a similar expansion downwards, there is a kind of semilunar notch formed betwixt it and the coccyx. The outer liga- ment may be said to arise from the side of the sacrum, and, like the other, is broad at that part. It runs for some time in contact with the inner ligament, and parallel to it; but afterwards it separates, passing down to be inserted in tho tuber ischii; and, when the ligaments separate, their surfaces are no longer parallel to each other. There is, in conse- quence of this separation, a small triangular opening formed betwixt the ligaments; or rather there is an aperture like a bow, the string being formed by the under ligament, and the 9 arch partly by the spine of the ischium, and partly by the upper ligament. § 3. VERTEBRAL JUNCTION AND OBLIQUITY OF THE PELVIS. The pelvis is joined to the trunk above, by means of the last lumbar vertebra; to the extremities below, by the insertion of the thigh bones into the acetabula; and it is so placed, that when the body is erect, the upper part of the sacrum and the acetabula are nearly in the same line. The brim of the pelvis, then, is neither horizontal nor perpendi- cular to the horizon, but oblique, being placed at an angle of 35 or 40 degrees. Were the ligaments of the pelvis loosened, there would, from this position, be a tendency in the sacrum to fall directly towards the pubis, the ossa innominata reced- ing on each side. But the structure of the part adds greatly to the power of the ligaments; for it is to be observed, that in standing, and in various exertions of the body, the limbs re- act on the pelvis; and the heads of the thigh bones pressing on the two acetabula, force the ossa innominata more closely on each other at the symphysis, and more firmly on the sacrum behind. It is not possible, indeed, to separate the bones of the pelvis, unless the connecting ligaments be diseased, or external violence be applied, so as to act partially or une- qually on the pelvis. . '"■ § 4. SEPARATION OF THE BONES. By external violence, the symphysis has been wrench- ed open, as was the case with Dr. Greene*; or the sacro- iliac junction may be separated, as in the case of the young peasant, related by M. Louis.f By some morbid affection of the symphysis, it may yield and become loosened during pregnancy, or may be separated during labour. Some have been inclined to consider this as an uniform operation of nature, intended to facilitate the birth * Phil. Trans. No. 484. f Vide Mem. de l'Acad. de Chir. Tome IV. p. 63. VOL. I. C 10 of the child. Others, who cannot go this length, have never- theless conjectured, that the ligaments do become some- what slacker; and have grounded this opinion on the sup- posed fact of the pelvis of quadrupeds undergoing this relax- ation. But the truth is, that this separation is not an advan- tage, but a serious evil; and in cases of deformed pelvis, where we would naturally look for its operation, did it really exist, we do not observe it to take place.(6) When a person stands, pressure is made upon the symphy- sis, and therefore, if it be tender, pain will then be felt. In walking, pressure is made on the two acetabula alternately, and the ossa innominata are acted on by the strong muscles which pass from them to the thighs, so that there is a ten- dency to make the one os pubis rise above the other; but this, in a sound state of the parts, is sufficiently resisted by (6) There is an animal however, in which this separtion of the bones of the pelvis during pregnancy and parturition does really take place, and in whom it appears to be an operation of nature to facilitate the latter process.—This animal is the Guinea Pig. Le Gallois says, that upon comparing the pelvis of the female of the Guinea Pig with the head of a full grown Foetus, it appears utterly impossible, that the latter should pass through the former, if the pelvis constantly preserved the state and dimensions at any other time than that of gestation. •When the female Guinea Pig is alive, the diameter of the pelvis is asserted to be but about one half of the head of the Foetus ; and nevertheless, Guinea Pigs are delivered with much ease. The duration of gestation in these animals being about 65 days.—About 3 weeks before delivery, the symphysis pubis is observed to acquire more thick- ness and a slight mobility; these are continually increasing. Eight or ten days before delivery, the two ossa pubis begin to separate from each other. This separation increases slowly at first, and only begins to go on rapidly for the three or four days which precede delivery.—At the moment of parturition, according to Le Gallois, it is such as readily to admit the middle finger, and sometime beth the middle and forefinger together. The delivery being accomplished, the bones of the pubis soon close. .Twelve hours after, the distance of the separation has lessened more than one Jhalf; and 24 hours after, they are in contact at their anterior extremity; and i^ less than three days they are perfectly so through the whole extent of their symphysis, which, then only presents a slight thickness and mobility. A few days after, nothing is to be seen. But when the females are old or sick, the union takes place more slowly. Vide Le Gallois's Experiments. Note at the end of the Vol. 11 the ligaments. In a diseased state, however, or in a case of separation of the bones, there is not the same obstacle to this motion: and hence, walking must give great pain, or be alto- gether impossible : even attempts to raise the one thigh above the other, in bed, must give more or less pain, according to the sensibility or laxity of the symphysis. Standing has also an effect on the symphysis, as I have mentioned ; but some- times the person can, by fixing one os innominatum, with all the muscles connected with it, and throwing the chief weight of the body to that side, stand, for a short time, easier on one leg than on both. This is the case when one os innominatum has been more acted on than the other, at the sacro-iliac junc- tion. The person can stand easiest on the soundest side. The patient also, especially if the relaxation be accompanied with any degree of relaxation of uterine attachments in- stinctively crosses her legs when standing, thereby obtaining relief. From these observations, we may learn the mischievous consequences of a separation of the bones, and also the cir- cumstances which will lead us to suspect that it has happened. If the bones be fully disjoined, then, by placing the finger on the inside of the symphysis, and the thumb on the outside, we can readily perceive a jarring, or motion, on raising the thigh. It is well known to every practitioner, that owing to the distension of the muscles during pregnancy, very consider- able pain is sometimes felt at the insertion, of the rectus muscle into the pubis; and it is also known, that sometimes, in consequence of pregnancy, the parts about the.pelvis, and especially the bladder and urethra, and even the whole vulva, may become very irritable. This tender state may bo com- municated to the symphysis; or some irritation, less in de- gree than that I have mentioned may exist, which, in par- ) Sutures should be very rarely had recourse to, as they give great irritation, and are subject to be torn out 59 a pledget, spread with simple ointment, to the part. If the radical cure fail, the patient must use a compress, retained with a T-bandage.23 § 12. IMPERFECTION OF THE VAGINA. The vagina may be unusually small. I have known it not above three inches long, and sometimes it is very narrow. The size, if necessary, may be enlarged with a tent of pre- pared sponge.* Should pregnancy take place before it be fully dilated, we need be under no apprehension with regard to delivery; for during labour, or even long before it, relaxa- tion34 takes place. Sometimes the vagina is wanting or im- pervious, or all the middle portion of the canal is filled up with solid matter. More frequently, however, there is only a firm septum stretched across, behind the situation of the hymen, or higher up in the vagina; and this2* it may be ne- cessary to divide. In some cases, there is a great confusion of parts, and, indeed, it is impossible to describe the varie- ties of conformation; for the vagina may follow a wrong course, or communicate with the urethra, or the rectum28 may terminate in the vagina, &c. Malformation does not always prevent pregnancy27. § 13. INFLAMMATION AND GANGRENE OF THE VAGINA. In consequence of very severe labour, inflammation, fol- lowed by gangrene of the vagina, may be produced. If the sloughs be small, then partial contraction of the diameter of the canal may take place, and cause much inconvenience from retention of the menses,28 or during a subsequent la- bour ; but in this last case, the parts gradually yield, and it is seldom necessary to perform any operation : the pain, however, i« sometimes excruciating till the part yield.f In some instances the sloughs are so extensive, that the whole vulva is destroyed, or part of the urethra and vagina • Vide Van Swieten Comment, in aph. 1290. f Harvey, exercit. LXX1II. p. 492. 60 come away, or general adhesion takes place, leaving only a small opening, through which the urine and the menses How. Should this, by any means be obstructed, the discharges can- not take place; and sharp pains, or even convulsions, may be the consequence. Sometimes calculous concretions form beyond the adhering part.* Whenever we have reason to expect a tender state of the parts after delivery, we must be exceedingly attentive; and if the vagina, or any other organ, be inflamed or tender, we must bathe the parts frequently, and inject some tepid water gently, to promote cleanliness. Saturnine fomentations and injections are often of service, but they must not be thrown high. The urine must be regularly evacuated ; and should a slough take place, we must, by proper dressings, or the use of a thick bougie, prevent coalescence of the vaginal canal29. § 14. INDURATION, ULCERATION AND POLYPI. The vagina may be contracted by scirrhous glands in its course, or induration of its parietes, which become thick and ulcerated, and communicate with the bladder or rectum. This disease is generally preceded by, or accompanied with, scirrhous uterus, and requires the same treatment. Foreign bodies in the vagina may produce ulceration, and fungous excrescences. The source of irritation being re- moved, the parts heal; but we must, by dressing and injec- tions, prevent coalescence. Polypous tumours may spring from the vagina, and are to be distinguished from polypus of the uterus by examination. The diagnosis betwixt polypus and prolapsus, or invcrsio uteri, will be afterwards pointed out. The cure is effected by the application of the ligature, more solito. t § 15. INVERSION. The vagina may be inverted or prolapsed, without any ina- * Vide Puzos Traite, p.^140.—Case by Mr. Purton, in Med. and Phvs. Jour. Vol. VI. p. 2 ': 61 terial change in the state of the womb, and without symptoms of uterine irritation, farther than slight pain in the back, and a little mucous discharge. We find a fleshy substance pro- truding at the back part of the vulva, having an opening be- fore, leading into the vagina. If the procidentia be consider- able, the rectum is carried forward, and in every instance is relaxed. At first the tumour is soft; but after sometime, if the part has been irritated, it may inflame, indurate, or ulce- rate. It is cured by strict attention to the state of the bowels, thereby preventing accumulation in the rectum, by astringent injections into the vagina, tonics, and, if these fail, by a globe pessary, or by pregnancy ;* but it sometimes returns after delivery.30 § 16. WATERY TUMOUR. Water sometimes passes down from the abdominal cavity, betwixt the vagina and rectum, protruding the posterior sur- face of the vagina in the form of a bag; and the accumula- tion of water in the cavity of the pelvis is sometimes so great as to obstruct the flow of the urine, or produce strangury. When the person lies down, the swelling disappears. If large, a candle held on the opposite side, sometimes shows it to be transparent; and in every case, fluctuation may be felt. As this symptom is connected with ascites, the usual treat- ment of that disease must be pursued, and, if necessary, the water may be drawn off by tapping the abdomen, or rather by piercing31 the tumour, which is to be rendered tense, by pressing it with the finger. § 17. HERNIA. Sometimes the intestine passes down betwixt the vagina and rectum, forming perineal hernia, or protrudes either at the lateral or posterior part of the orifice of the vagina, like the watery tumour; but is distinguished from it by its firmer * Pechlin, lib. i. obs. 20. 62 and more doughy feel, and by the manner in which it can be returned. By handling it, a gurgling noise may be heard, and sometimes indurated feces may be felt. As the os uteri is pushed forward and the posterior part of the vagina occu- pied by the herniary tumour, this complaint may put on some appearance of retroverted uterus. A case of this kind is mentionedby Dr. John Sims,in Mr. Cooper's work on hernia. This complaint is frequently attended with a bearing-down pain; and on this account, as well as from its appearance, it has also been mistaken for prolapsus uteri. Sometimes the tumour does not protrude externally; but symptoms of stran- gulated hernia may appear, the cause of which cannot be known, unless the practitioner examine the vagina. In a case occurring to Dr. Maclaurin, and noticed by Dr. Den- man, the patient died on the third day, and the disease was not discovered till the body was opened. Should a woman have vaginal hernia during pregnancy, we must be careful to return it before labour begin, for the intestine may become inflamed, and the feces obstructed, by the head entering the pelvis; or the labour itself, if the head cannot be raised and the intestine returned, may be impeded so much as to require the use of instruments. Vaginal hernia requires the use of a pessary. The rectum sometimes protrudes into the vagina, and al- ways does so more or less in an inversio vagine. This is remedied by the globe pessary, after all the indurated feces have been removed. The farther accumulation is prevented by laxatives. § 18. ENCYSTED TUMOURS AND VARICES. Indolent abscess, or encysted tumours, may form betwixt the vagina and neighbouring parts. These are distinguished from hernia and watery tumours, by being incompressible, and not disappearing by change of posture. The history of the disease assists the diagnosis, and examination discovers the precise seat and connections of the tumour, though it - annot with certainty point out the nature of the contents. 63 These tumours seldom afford obstinate resistance to delivery; by degrees they yield to the pressure of the head, but some- times they return after delivery. The treatment is similar to that required in other cases of tedious labour, and the tumour must be opened if we cannot deliver the woman otherwise, with safety to the child. Even in the unimpreg- nated state, if it cause irritation, or if the bulk of the tumour be so great as to impede the evacuation of the urine or feces, an opening must be made. After delivery, in those cases where no operation is performed, the tumour sometimes in- flames and indurates even so low as the perineum. Friction on the perineum, has in these circumstances done good. Varicose tumours of a knotted form, disappearing or be- coming slack by pressure, and aneurismal tumours, distin- guishable by their pulsation, may form about the vagina, and ought not to be interfered with, except by supporting them w ith a globe pessary in the vagina. § 19. SPONGOID TUMOUR. A very dreadful disease, which I have called spongoid tu- mour, may form either within the pelvis, or about the hip joint, or tuberosity of the ischium, and spread inwards, pres- sing on the bladder and rectum, sometimes so much as to re- quite the use of the catheter. We recognise the disease, by its assuming very early the appearance of a firm elastic tu- mour, as if a sponge were tied up tightly in a piece of bladder. Presently it becomes irregular, and the most prominent parts burst, discharging a red fluid, w hich is succeeded by fungous ulceration. But I have never known it proceed to this last stage within the pelvis. I know of no remedy, and would dissuade from puncturing, except in the very last extremity. I have never met with a case where it was necessary. §20. ERYSIPELATOUS INFLAMMATION. The orifice of the vagina, together with the labia, and indeed the whole vulva, may be affected by erysipelatous 64 inflammation. This appears under two conditions: 1st, it may originate in the vulva, and spread inwards, even to the uterus; or, 2dly it may begin in the womb, and extend out- wards. The parts are tumid, painful, and of a dark red colour. The second affection is most frequent after parturi- tion ; but the first may occur at any age, and under a variety of circumstances. It may be confined to the external parts alone, or it may quickly spread within the pelvis, and destroy the patient; for this disease generally terminates in gan- grene. Vigarous,* says, this state may be distinguished from abscess of the labium, by both labia being equally affected. The general history of the case, and proper exami- nation, will point out the difference. When the disease is confined to the external parts, we may hope for a cure, and even for the preservation of the parts, by giving early, bark and opium internally, and applying to the surface, pledgits dippedin a w eak solution of sulphate of zinc, with the addition of a tenth part of camphorated spirit of wine. When this application gives continued pain, fomentations with milk and water, or with decoction of chamomile flowers may be sub- stituted. A highly sensible or inflamed state of the parts may occur in nymphomania, or libidinous madness, either as a primary or secondary affection; and should the patient die under the disease, the parts are generally found black. The tepid bath and fomentations give relief, but sometimes spirituous applica- tions are beneficial. If the patient be feverish she ought to be blooded, and have cathartics administered, and be put on spare diet. Nauseating doses of tartar emetic, or full doses of the medicine, given so as to operate briskly, are of service, especially if followed by sleep. Strict and prudent attention must be paid to the mind. A constant heat and tenderness of the parts, if not occasioned by uterine disease, may be relieved by bathing with solution of sulphate of zinc. * Maladies des Femmes, Tome II. p. 169. 65 § 21. FLUOR ALBUS. The vagina is always moistened with a fluid, secreted by the lacune on its surface. To this is added the secretion from the glands of the cervix uteri and the serous exhalation from the membrane of the uterine cavity. Naturally the balance between secretion and absorption is such, that except on particular occasions, no fluid is discharged from the va- gina. But in a diseased state, the quantity of the secretion is greatly increased, and the discharge, whether proceeding solely from the vagina, or partly also from the womb, re- ceives the name of fluor albus, or leucorrhoea. Some confine the term strictly to a discharge from the inner surface of the womb ; and in order to determine whether the secretion proceeds from the uterus or not, it has been proposed to stuff the vagina completely for some time, and then inspect the plug, to ascertain whether that part corresponding to the os uteri be moistened.* But this test is not satisfactory, and will seldom be submitted to. When the discharge proceeds from the womb, it some- times injures the function of that organ so much, or is de- pendent on a cause influencing the uterus so strongly, as to interfere with menstruation, either stopping it altogether, or rendering it too abundant or irregular in its appearance, and in such cases the woman seldom conceives. Very fre- quently, however, the menses do continue pretty regularly ; and in those cases, the other discharge disappears during the flow of the menses, but is increased for a little before and after menstruation. When the menses are obstructed, it is not uncommon for the fluor albus to become more abun- dant, and to be attended with more pain in the hack about the menstrual period. If a woman, who has uterine leucor- rhoea conceives, the discharge stops, but a vaginal secretion is, on the contrary, not unfrequently increased. This it has been thought dangerous to check suddenly, but it ought not to be allowed to continue profuse, as it causes abortion. * Chambon Malad. des Filles, p. 104. VOL. I. K 66 Fluor albus may occur in two very different states of the constitution, either as an effect of these, or produced in them by accidental causes. These are a state of plethora, or dis- position to vascular activity, and a state of debility. The one is marked by a full habit, a good complexion and a clear healthy skin. The other by a pale countenance, a sal- low surface, a feeble pulse, and generally a spare habit. The one is attended with vertigo, or disease produced by ful- ness. The other by dyspepsia, palpitation, and those com- plaints which are connected with debility. The discharge is produced either by the lacune of the va- gina, or the glandular and cxhalent apparatus of the uterus. The most ample and the most frequent source is from the vagina. The discharge itself may consist simply of the natural mucus of the part increased in quantity, in which case it is glairy and transparent; or it may be so far changed as to become opaque, and white like milk, which is par- ticularly the case when the organs of secretion of the upper part of the vagina and cervix uteri are affected; or it may be purulent. These may all occasionally be mixed with a little blood from the uterine vessels, if there be a tendency to menorrhagia, but not otherwise, unless there be organic disease. In those cases where the discharge is yielded by diseased structure, it is modified by the nature of that struc- ture, and by the existence of ulceration and erosion. When it proceeds from the morbid part itself and not from the irritating effects of that part on the vagina, by sym- pathy, it is generally foetid, and purulent, often of a dark colour mixed with blood, and alternated by uterine hemorr- hage. There is often heat about the parts, and other symp- toms of disease. In all ambiguous, and in every chronic case, it is necessary to examine carefully the state of the uterus and vagina. We must bear in mind that fluor albus may be caused by local irritation, including the effect of diseased structure, or misplaced uterus; by a state of increased vascular action; and by debility, either preceded by increased action, or di- rectly produced by weakening causes. 67 Fluor albus is usually accompanied with pain, and sense of weakness in the back. The functions of the digestive organs are always ultimately injured, and in those women who are of a weak habit, they are impaired from the first. In them the discharge adds greatly to the debility, and all the diseases arising from that state increase, such as indigestion, derange- ment of the hepatic secretion, torpor of the bowels, palpita- tion, swelling of the feet, &c. In the more plethoric patients the debilitating effects are longer of appearing, but they are not exempted from affection of the stomach. Fluor albus may be excited by the presence of a polypus in utero, or in consequence of prolapsus uteri, or of disease of the womb; but in such cases it is symptomatic, and is not at present to be considered. The idiopathic fluor albus may be produced by various exciting causes, such as abortion, menorrhagia, frequent parturition, excessive venery, cold or fatigue after a miscarriage or a delivery at the full time, and whatever can weaken the action of the uterus.* It was at one time supposed, that it might also be produced by a bad state of the fluids of the body, a bilious cacochymy, a leuco- phlegmatic habit, passions of the mind, &c. The applica- tion Of cold or other circumstances exciting irritation of the vaginal membrane may produce it in the same way as they produce catarrh. Worms may cause it. In treating fluor albus we must consider whether it be symptomatic of polypus, prolapsus, or cancer, &c. If it be not, we have then to attend to the general state of the con- stitution. Should the patient be plethoric, or robust, it is necessary, In the first instance, to diminish the fulness and activity of the vessel, by mild, and perhaps, spare diet, by moderate doses of laxative medicine, and even, if requisite, by the lancet. Regular exercise, is in this view, of benefit, but in all cases fatigue increases the discharge. Then we give bitters with alkali to improve the state of the stomach and bowels, and employ an injection of solution of acetite of lead, which is to be thrown three or four times a day into * Chambon Malad. des Filles, p. 104. 68 the vagina, and this may afterwards be exchanged for one of a more astringent quality. If the disease occur in a weak habit, or if the plethoric state, though it existed at one time, has now been removed, the internal remedies must be more directly tonic, and injec- tions of various astringents must be employed; of those the two best are solution of sulphate of alumin and decoction of oak bark. The action of cold and damp are to be avoided, as these are hurtful in every affection of mucous membranes, whether chronic or acute. Of the internal remedies some are intended to act by sympathy on the secreting parts, as emetics, others as general tonics. Emetics are of very con- siderable advantage, on account of their operation on the stomach and alimentary canal, and are accordingly advised by most writers.* Purges have also been used,f in order to cany off noxious matter; but they are only to be given, so as to keep the bowels regular,:): for brisk and repeated purg- ing is hurtful.^ Tonic medicines and those which improve the action of the chylopoetic viscera, such as lime water, myrrh, bark, steel, rhubarb, uva ursi, &c. are also of much utility, and along with them we may, with great advantage, employ the cold bath. The diet is to be light and nourishing, and the patient ought not to indulge in too much sleep. Various medicines have been proposed with a view of act- ing specifically on the secreting parts, such as cicuta, balm of gilead, diuretic salts, calomel, resins, cantharides, electri- city, arnica, &c. have been proposed; but they have very little good effect, and sometimes do harm. Of all these the tincture of cantharides(^) and oil of turpentine, by exciting • Smellie, Vol. I. p. 67.—Vigarous, Tome I. p. 261.—Mead Med. precepts, chap. XIX. sect. 3d.—Denman, Vol. II. page 104.—See also Ettmuller, Ri- verius, &c. && f Chambon Malad. des Filles, p. 107.—Mead, Med. precepts, chap, xix, section 3d. * Stoll. Prxlectiones, Tomus II. p. 385. § Vigarous, Malad, des Femmes, Tome I. p. 261. (q) Mr. Roberton a surgeon of Edinburgh in a paper published in the London Medical and Physical Journal, vol. XV. and also in a distinct work on the Eflects of Cantharides, when taken internally, strongly recommends 69 the uterine vessels in chronic secretions seem to be the best, but no internal medicine can be much depended on in this view. By suckling a child, the discharge has in some in- stances been removed. Plasters and liniments have been applied to the back, and sometimes relieve the aching pains. Opiates are occasionally required, on account of uneasy sen- sations. When the discharge is very opaque, and attended with considerable pain in the back and loins, there is reason to think that the cervix uteri is in a state of irritation, and by examination it may be found tender to the touch, and the mouth soft and enlarged a little. This state does not con- stitute disease of structure though it may lead to it, but it con- sists merely in an affection of the glands. It is to be man- aged in the first stage, by the warm sea water hip-bath, mild mercurial preparations, laxatives, and avoiding all irritation. After the tender state is nearly subdued, and the discharge has become more chronic, the cold bath, tonics, and mild vegetable astringent injections are proper. Purulent discharge implies previous inflammation, and the present existence either of abscess, ulceration, or a morbid change of a secreting surface. The two first states are ascer- tained by examination. The last chiefly by the smarting in making water, and other symptoms excited by the action of a virus. To this species belongs the gonorrhoea, which is to be cured by mild laxatives, and injections, first of acetite of lead, and then of sulphate of zinc, dissolved in water. The two first states are to be managed according to the causes which give rise to them. this powerful article of the materia medica, in obstinate cases of Leucor- rhoea; and recites a number of instances, in which it appears to have pro- duced the best effects. In his exhibition of this medicine, he generally begun with about Jij or Jijss of the tincture, in ^vj of water; a table-spoonful of which was given thrice a day. He continued gradually increasing the dose, until his patient had taken Jiv of the tincture in 24 hours, 3jj of the tincture being added to gvj of water. It was generally given, until con- siderable pain, and a puriform discharge from the vagina was produced. I cannot say, that in the few trials I have made of it in this complaint, the beneficial effects have been so conspicuous. 70 On the whole then, our practice in fluor albus, unaccom- panied with organic affection, consists in rectifying the con- stitution, bringing it as far as possible to a state of perfect health, employing topical applications in the form of injec- tions, and avoiding the farther operation of exciting causes. § 22. AFFECTIONS OF THE BLADDER. The bladder is subject to several diseases. The first I shall mention is stone. This excites very considerable pain in the region of the bladder, remarkably increased after making water. There is also irritation about the urethra, with a frequent desire to void the urine; but it does not always flow freely, sometimes stopping very unexpectedly. The urine deposits a sandy sediment, and is often mixed with mucus. These symptoms lead to a suspicion that there is a stone in the bladder, but we can be certain only by pas- sing a sound. By means of soda,(r) the warm bath, and (r) Our author has omitted to mention the efficacy of magnesia in calcu- lous complaints, as recommended by Messrs. Brande and Hatchet. The result of the inquiries of these ingenious gentlemen, on this very interesting sub- ject, has been communicated to the scientific world in a paper printed in the Philosophical Transactions for the year 1810, entitled " Observations on the Effects of Magnesia, in preventing an increased formation of the Uric Acid, by William T. Brande." This gentleman (in a communication to Sir John Sinclair) says, that the best method of giving the magnesia, is in plain water, or milk, to be taken in the morning early, and at mid-day. If the stomach is weak, and this produces flatulency or uneasy sensations, some common bit- ters, such as gentian, may be taken with it: if it purges, a little opium may be added. He supposes its beneficial operation depends, on preventing the for- mation of acid in the stomach. The dose of magnesia, he observes, must always depend upon the circum- stances of the case ;—generally, five grains twice or thrice a day to children ten years of age ; fifteen or twenty grains to adults. Mr. Brande has always given the common magnesia, although he remarks, that, the calcined may be occasionally used with advantage. For fuller infor- mation on this subject, the reader is referred to Brande's paper, above quoted, in the Phil. Trans, and to a letter from Sir John Sinclair, vide Eclectic. Reper- tory, vol. III. p. 120. ■ Dr. Gilbert Blane, so well known in the medical world, has also written an interesting paper on the effects of large doses of mild vegetable alkali, or potassa carbouata in gravel, and the beneficial effects of opium combined with it. n opiates, much relief may be obtained, and very often the stone may be passed, for the urethra is short and lax. But when these means fail, an operation must be performed. This has been done during pregnancy,* but is only allow- able in cases of great necessity. Sometimes the stone makes way, by ulceration, into the vagina.f It has even been . known to ulcerate through the abdominal integuments.:}: In many cases the symptoms of stone arc met with, although none can be found in the bladder. This is most frequently the case with young girls, previous to the establishment of the catamenia, or with women of an irritable habit. There is no organic disease, nor have I ever known it, in such peo- ple, end in a diseased structure of the bladder or kidneys; indeed, they rarely complain of uneasiness about the kid- neys. I have tried many remedies, such as soda, uva ursi, narcotics, antispasmodics, tonics, and the warm and cold bath, but cannot promise certain relief from any one of these.33 In process of time, the disease subsides and disap- pears. The use of a bougie may be of service. Induration, or scirrhus of the bladder, produces symptoms somewhat similar to calculus, but there is a greater quantity of morbid mucus mixed with the urine ; and blood with pu- rulent matter is discharged, when ulceration has taken place. No stone can be found, but the bladder is felt to be hard and thick. Sometimes it is much enlarged with such appear- ances, as give rise to an opinion, that the uterus is the part principally affected.34 The scirrhus and ulceration may ex- tend to the uterus and vagina. In this disease we must avoid all stimidants, and put the patient on mild diet; avoid every thing which can increase the quantity ofsaltsin the urine; keep the bowels open, with an emulsion containing oleum ricini; and allay irritation by means of the tepid bath and opiates. Mercury, cicuta, uva ursi, &c. with applications to the blad- der itself, have seldom any good effect, and sometimes do harm. * Deschamps Traite de l'Oper. de la Taille, Tome IV. p.9 f Hildanus, cent. I. obs. 68 and 69. , Vide Case by M. Caumond in Recueil Period. 72 Chronic inflammation of the mucous membrane of the blad- der, produces frequent desire to void urine, and the discharge of viscid mucus which sometimes has a puriform appearance. Cicuta and balsam of copaiba seem to be the best remedies. Polypous tumours8* may form within the bladder, produc- ing the usual symptoms of irritation of that organ. Most dread- ful sufferings have been caused by worms in the bladder. In consequence of severe labour, or the pressure of instru- ments, the neck of the bladder may become gangrenous, and a perforation take place by sloughing. The woman com- plains of soreness about the parts, and does not void the urine freely. In five or six days the slough comes off, and then the urine dribbles away by the vagina. In all cases of severe labour, and indeed in every case wrhen the urine does not pass freely and at proper intervals, and especially if there be tenderness of the parts, we must evacuate the water, in order to prevent distension and farther irritation of the bladder; and the parts must, if there be a tendency to slough or to ul- cerate, be kept very clean, and be regularly dressed, in order to prevent improper adhesions. If the bladder should give way, we must try, by keeping in attentively an elastic cathe- ter,* to make the urine flow by the urethra, and then perhaps the part may heal. If this have been neglected, it will be proper to make the edges of the opening raw by paring, if it be large, or by caustic if it be small, and afterwards use the catheter. When an incurable opening is left, we must, by introducing asponge, or some soft, but pretty large substance, like a pessary, into the vagina, close it up, at least so far as to make the woman more comfortable. In a curious case I met with, there was an attempt by nature, to plug up the opening.36 Puzos justly remarks, that it is always the blad- der, and not the urethra, that suffers. Sometimes, after a severe labour, the woman is troubled with incontinence of urine, although the bladder be entire. This state is often produced directly by pressure on the neck * This succeeded in a very bad case related by SedUliot, Recueil Period. Tome I. p. 187. 73 of the bladder; sometimes it is preceded by symptoms of in- flammation about the pelvis, and, in such cases, the os uteri is often found afterwards to be turned a little out of its proper direction, and the patient complains much of irregular pains, about the hypogastrium and back. When the woman is in bed some of the urine collects in the vagina, and comes from it when she rises; after she is up, it comes from the urethra alone, which distinguishes this from the complaint last described. Time sometimes cures this disease. The cold bath is useful, unless it increase the pain; and, in that case, the warm bath should be employed. It may be proper to use the bougie daily, and also try the effect of tincture of cantharides. The bladder may descend, in labour, before the uterus, pro- ducing much pain; or it may prolapse for some time previous to labour, attended with pains resembling those of parturition, and sometimes with convulsive or spasmodic affections.37 When the prolapsus vesice takes place as a temporary oc- currence during labour, or antecedent to parturition, we must be careful not to mistake the bladder for the membranes, for thus irreparable mischief has been done to the woman. The bladder when protruded, is felt to be connected with the pubis. It retires when the pain goes off. If the patient be not in la- bour, the uneasiness is to be mitigated by keeping the bladder empty, and allaying irritation with opiates, and taking a little blood if feverish or restless. If labour be going on, the blad- der must likewise be kept empty, and may, during a pain, be gently supported, by pressing on it with two fingers in the vagina, by which the bladder is preserved from injury. In the unimpregnated state, it sometimes descends betwixt the vagina and pelvis, so as to form a tumour within the vagina, or at the vulva. It produces a procidentia of the vagina, but the tumour is formed at the anterior part of the vulva, instead of the back part, as in the ordinary procidentia. There is some degree of bearing-tlown pain in walking, particularly when the bladder is full. Some patients complain of pain in the groin, others at the navel, and some suffer little or no in- convenience, except pain about the bladder when it is dis- tended. If the disease has continued long, or if the prociden- vol. i. L 74 tia of the anterior part of the vagina be considerable, the os uteri is directed backward, and when the finger is introduced into the vagina, the anterior part of that canal can be pushed up farther than usual over the fore part of the cervix uteri, which then appears to be elongated, and perhaps in some cases the anterior lip is actually lengthened. In a case dis- sected by my brother, the bladder was found to form a hernia on both sides of the pelvis, hanging like a fork over the ure- thra. This procidentia is called a hernia* vesicalis, and is often attended with suppression of urine. If this be inatten- tively examined, it may be taken for prolapsus uteri; but it will be found to diminish, or even disappear, when the urine is voided, and by pressure, the urine may be forced through the urethra. The hernia vesicalis is to be remedied by the use of a globe pessary. Sometimes it is combined with cal- culus in the bladder. In this case, it has been proposed to open the bladder, extract the stone, and keep up a free dis- charge of urine through the urethra, in order to allow the communication with the vagina to heal. Deschamps advises, that the opening should be made near the pubis, and not at the posterior part of the tumour, lest that part of the bladder be cut, which, when the tumour is reduced, would communi- cate with the abdominal cavity. I can see no necessity for making any change in the mode of extracting the stone on account of the procidentia. § 23. EXCRESCENCES IN THE URETHRA. Excrescences may, notwithstanding the opinion of Mor- gagni, form in the course, or about the orifice of the ure- thra,38 and generally produce great pain, especially in mak- ing water; on which account, the disease has sometimes been mistaken for a calculous affection. The agony is at times so great, as to excite convulsions, and it is not un- common for the patient to have an increase of her sufferings * Vide the Memoirs and Essays of Verdier and Sabbatier, and Hoin. Sandi- fort, Diss. Anat. Path. lib. I. cap. iii. and Cooper on Hernia, part 11. p. 66. 75 about the menstrual period. The tumour is vascular, florid, moveable, and exceedingly tender. When excrescences grow about the orifice of the urethra, they are readily dis- covered ; but when they are high up, it is much more diffi- cult to ascertain their existence. Dr. Baillie* says, they cannot be known, but by the sensation given by the catheter passing over a soft body. They, however, in one case, were discovered, by turning the instrument to one side, so as to open the urethra a little.39 When their situation will per- mit, it is best to extirpate them with the knife or scissars ; or if near the orifice, as they generally are, a ligature may be applied. Sometimes they have yielded to the bougie, though they had returned after excision.f The removal of large excrescences, has occasionally been attended with very severe symptoms.40 The daily use of the bougie, for some time after extirpation, is of service.41 Sometimes the urethra is partially, or totally inverted,48 forming a tumour at the vulva, attended with difliculty and pain in voiding urine. A slight inversion may be relieved by a bougie; when there is a considerable prolapsus, the part must be cut off. The urethra is sometimes contracted by a varicose state of its vessels, or by a stricture: but these are not common occurrences. In continued irritation of the urethra, with difliculty of voiding water, the bougie is often of great service, even although there should be no con- traction of the canal itself. Sometimes the urethra is prefer- naturally dilated,43 but this does not necessarily cause incon- tinence of urine. The mucous coat of the urethra is sometimes thickened, and its vessels become varicose. This produces general swelling of the urethra felt by the finger in the course of it, pain or pressure, and in coitu, with a discharge of mucus, and tormenting desire to make water. When the patient bears down, the urethra is partially inverted, and appeals swelled and vascular. These vessels should be scarified, the • Morbid Anatomy, p. 321. t Broomfield's Surgery, Vol. II. p. 296. 7& part bathed with an astringent lotion, and gentle pressure made with a thick bougie. § 24. DEFICrENCY AND MAL-FORMATION OF THE UTERUS. The uterus may be larger than usual, or uncommonly small44, or it may be altogether wanting45. Unless these circumstances be combined with some deficiency, or unusual conformation of the external parts or vagina, the peculiar organization is not known till after death. It is, however, not uncommon for the external parts to be very small, when the uterus is of a diminutive size; and when it is altogether wanting, the vagina is either very short, or no traces of it can be found. In either of these cases, no attempts should be made to discover a uterus by incisions, unless, from symp- toms of accumulation of the menses, we are certain that a uterus really exists.* The uterus may be double48: in this case there is some- times a double vagina, but generally only one ovarium and tube to each uterus. This conformation does not prevent impregnation. The uterus is sometimes divided into two, by a septum stretching across at the upper part of the cervix ;f or the os uteri is almost, or altogether shut up,47 by a continuation of the lining of the womb or vagina, or by adhesion, consequent to ulceration, or by original conformation; and in this last case, the substance of the os uteri is sometimes almost car- tilaginous. The menses either come away more or less slow- ly, according to the size of the aperture, or are entirely re- tained when there is no perforation. As long as the menses are discharged, nothing ought to be done; but if they are completely retained, and violent and unavailing efforts made for their expulsion, an opening must, as a matter of neces- sity, be made from the vagina. In such cases, the uterus * Nabothus mentions a rash operator, who undertook, by incision, to find the uterus; but after cutting a little, he came to some vessels which obliged him to stop. ~ Baill'.e-? Morbid Anatomy, chap, xix, 77 has been tapped with success ;* but it has also happened, that fatal inflammation has succeeded the operation. The vessels are sometimes enlarged; and I have seen the spermatic veins extremely varicose, in an old woman who had been subject to piles; but I do not know that any particular inconvenience results from the veinous enlargement. § 25. HYSTERITIS. The uterus is subject to inflammation; but in the unim- pregnated state, it is not common for the womb to be the original seat of acute inflammation. After parturition, it is very frequently inflamed, and this will hereafter be consider- ed. Inflammation is discovered by pain in the hypogastric region, accompanied with tension, and the part is tender to the touch; there is acute pain stretching to the back and groins; the bladder is rendered irritable; and acute fever accompanies these symptoms. Blood letting, purges, fomen- tations, and blisters are to be used, as in other cases of peri- toneal inflammation. Wounds of the uterus are dangerous, in proportion to the inflammation they excite.f Chronic inflammation of the cervix uteri is not uncommon. The os uteri is open, soft, and tender to the touch. The cervix is not materially affected in size or hardness. There is a considerable discharge of white mucus which sometimes becomes puriform, and this is often mixed with blood; or there may be very considerable uterine hemorrhage. The patient feels pain in the uterine region, but generally com- plains more of pain in some distant part of the abdomen, not unfrequently near the liver. There is no fever, but the pa- tient becomes weak from discharge, irritation, and those hysterical affections which may accompany the complaint. The warm sea-water hip-bath, gentle saline purgatives, * The menses being retained, and great pain excited, they were let out with a trocar by Schutzer. Vide Sandifort, p. 69. -j- In one instance the woman was murdered, by thrusting a piece of glass up the vagina; and Haller notices a fatal case, in which a piece of lead was thrust into the uterus. 78 injection of decoction of hemlock, mild diet, and the use of cicuta as an anodyne are useful at first; and afterwards when the symptoms are so far subdued, the use of the cold sea-bath, bark combined with bitters, and mild injections of vegetable astringents are proper. In obstinate cases mer- cury ought to be tried, with a view of altering the action of the parts, «j 26. ULCERATION OF THE UTERUS. The uterus may, from irritation, become ulcerated like any other part; purulent matter is discharged, the woman feels pain in coitu, or when the uterus is pressed, and some- times the finger can discover the ulcer. Simple ulceration is very rare, and, I apprehend, will always heal, by keeping the parts clean with mild injections. Ulceration from mor- bid poison is more frequent. Of this kind is the phagedena, a most obstinate and dreadful disease of the womb, which begins about its mouth, and goes on, gradually destroying its substance, until almost the whole of it be removed; and sometimes it spreads to the neighbouring parts. This dis- ease is marked by excruciating pain of the burning kind, in the region of the uterus, copious foetid, purulent, or sanious discharge, alternating with some hemorrhage, small but fre- quent pulse, wasting of the flesh, and occasionally swelling of the inguinal glands: no tumour is felt externally, but the belly is flat. Examination, per vaginam, discovers the destruction which has taken place, and how far it has pro- ceeded. It also ascertains, that the part which remains is not enlarged. On inspecting the body after death, the pelvis is gene- rally found filled with intestines, matted, and adhering to the pelvis, and to one another. In the midst of the mass, there are sometimes one or two simple abscesses, containing healthy pus. On tearing out the mass, the uterus is discover- ed to be ate away all to the fundus, or a small part of the body. The substance is very little thickened, but resembles soft cartilage, with here and there small cysts, not larger 79 than pin heads. The ulcerated surface is dark, flocculent, and has a dissolved appearance, whilst the substance in its immediate vicinity is vascular and livid. The rapidity of the destruction is various in different cases. It is very diffi- cult to cure this ulcer, or even to check its progress. Some- times mercury has effected a cure, either by itself, or com- bined with cicuta; or hyocyamus, or other narcotics, have been given alone. Nitrous acid occasionally gives relief, and, when greatly diluted, forms a very proper injection. A very weak solution of nitrate of silver, is also a good topi- cal application. Should the pain be great, tepid decoction of poppies, or water with the addition of tincture of opium, will be of service as an injection. Fomentations to the lower belly, and friction with camphorated spirits on the back, also give relief; but very frequently opium, taken in- ternally, affords the only mitigation of suffering, and the quantity required is often great There is another kind of ulcer, which attacks the cervix and os uteri. It is hollow, glossy, and smooth, with hard margins; and the cervix, a little beyond it, is indurated, and somewhat enlarged, but the rest of the uterus is healthy. The discharge is serous, or sometimes purulent. The pain is pretty constant, but not acute; and the progress is generally slow, though it ultimately proves fatal, by hectici In this, and all other diseases of the uterus, the morbid irri- tation generally excites leucorrhoea, in a greater or less de- gree ; but examination ascertains the morbid condition of the part. Although this disease be very different in its na- ture from the former, yet the mode of treatment is very much the same. Material benefit may he derived from the warm salt-water bath, and the regular use of a solution of some saline purgativ e, or a laxative mineral water, such as that of Harrowgate or of Cheltenham. This is especially the case, when the ulcer is small, or when the part is only indurated, ulceration not having yet taken place. In this stage, the cervix is felt hard and sensible to the touch, and there is leucorrhoea, and pain in the uterine region. A gentle mercurial course is occasionally of service. Some 80 may consider this disease as a species of cancer, but the ulcer is never fungous. Excrescences of a firm structure, and broader at the ex- tremity than at the attachment, may spring from theos uteri, and generally, I apprehend, originate from a lobulated or fis- sured state of the parts. It bleeds readily and profusely, but when it is not irritated, the discharge is serous and so great, that thick folds of cloth are soon wet as if the liquor amnii had been coming away. It is evident that astringents cannot ef- fect a cure, as they do not alter the nature of the substance which secretes. If a ligature could be passed so as to destroy the circulation in the excrescence, a cure might be expected. When this cannot be done we can only palliate symptoms. Venereal ulceration may, although the external parts be sound, attack the uterus, producing a sense of heat with pain. There is at first, very little discharge, and this consists of mucus; but if the disease be allowed to continue, foetid puru- lent matter comes away. The ulcer is at first small, and there is no hardness about the os uteri, nor is it perceived to be di- lated; but it is painful to the touch, and sometimes bleeds after coition. The purulent discharge appears earlier than in can- cer, but the health for a time is not affected. Then the ulcer spreads, and mayjdestroy a great part of the womb and blad- der, and occasion fatal hectic. The history of the patient may assist the diagnosis. The cure consists in a course of mercury, which I have always found produce a good effect soon after the commencement.* § 27. SC1RRO-CANCER. Scirro-cancer generally, if not always, begins in the cervix uteri. It may take place in the prime of life, but is most fre- quent about the time of the cessation of the menses. It be- gins with a feeling of heaviness or heat, and darting pains about the hypogastrium, aching in the back, dull pain about the upper and inner part of the thighs, with a sense of bearing- * Vide Med. Comment. Vol. XIX. p. 257.—Pearson on Cancer, p. 119. 81 down, together with dysuria and mucous discharge with the urine; glowing heat, or sometimes stinging pain betwixt the pubis and sacrum, with itchiness of the vulva. There is from the first, a leucorrhoeal discharge. The patient is troubled with flatulence, heartburn, and sometimes with vomiting, and cutaneous eruptions from sympathy with the stomach. The general health suffers, the countenance becomes sallow, the pulse quickens, the strength declines, and the body wastes. If the menses have not entirely ceased, they become irregular and profuse. Presently a foetid, purulent, or bloody matter is discharged, which indicates that a cyst has burst, and the disease has proceeded to ulceration. Repeated hemorrhages are now apt to take place, and hectic is established. The pain is constant, but subject to frequent aggravations, and the weakness rapidly increases. At length the pain, fever, want of rest, discharge, and loss of blood, completely exhaust the patient; and death terminates at once both her hopes and sufferings. At fii ;t, by examination per vaginam, the uterus is felt as if it were enlarged; the cervix is thickened, and the os uteri hard, open, irregular, and more sensible to the touch, a cir- cumstance which causes pain in coitu. The cervix is either totally indurated, or has imbcdcd in it a hard tumour, which may acquire considerable size. A little blood is often observed on the finger after an examination. In some time after this, the os uteri is turgid, as if it contained a small cyst, and pre- sently it is felt to be ulcerated and fungous; but sometimes the fungi are less perceptible, deep excavations being formed, the sides of which, however, after death, are found to be fun- gous. The cervix uteri is sometimes considerably enlarged before ulceration takes place; but, in other cases, the augmentation is much greater after ulceration, than before it.48 If the dis- ease originally formed a distinct tumour in the cervix, that tumour may become as large as the first, adhering to the pel- vis so that it cannot be moved, and pressing so much on the rectum or bladder, according to its situation, as to give rise VOL. I. M 83 to much obstruction in the evacuations from either of these parts. The uterus itself is seldom much enlarged in genuine cancer, but it is possible whilst the cervix is affected with this disease, that the body of the uterus may have undergone a different morbid change. The tubes and ovaria have been said to participate in the disease.* In some patients the disease proves fatal very early if there be profuse hemorrhage; in others, great devastation takes place, and the bladder49 or rectumf are opened. In most cases, the vagina becomes hard and thickened, or irregularly contracted with swelled glands, in its course. On examining the diseased part after death, it is found to be thickened and indurated, and sometimes its cavity is en- larged. The substance is of a whitish or brownish colour, in- tersected with firm membranous divisions ; and betwixt these are numerous small cysts, the coats of which are thick and white. They contain a vascular substance, which, when wiped clean, is of a light olive colour. In proportion as the disease advances, some of the cysts enlarge, and thicken still more; and, when opened, are found to contain a bloody lymph, and to have the inner surface covered with a spongy vascular substance, similar to that which fills the small cysts, but rather more resembling fungus. Presently some of these cysts augment so much as to resemble abscesses, though they are not properly speaking abscesses, and soon afterwards they burst. It is extremely rare for a cyst to burst, or fungi to shoot out on the exterior surface of the uterus, which is covered with the peritoneum. The position of the uterus is often na- tural, but sometimes it is inclined to one or other side, or approaches to a state of retroversion. As this disease is apt to be mistaken for fluor albus, me- norrhagia, nephritis, or dyspepsia, it is of great importance that the practitioner should be on his guard, and examine * Vide Prochaska Annot. Acad. fasc. 2d. | M. Tenon found, in a case of cancerous uterus, all the posterior part of the womb ulcerated, the rectum diseased, and a communication formed betwixt ♦hem. 88 early and carefully per vaginam. Much harm is done by the use of astringent injections meant to cure the supposed fluor albus. This is .a very hopeless disease, but still much may be done to check its progress, or mitigate its symptoms. When un- easy sensations, about the cessation af the menses, indicate a tendency to uterine disease, we find advantage from the insertion of an issue in the arm or leg, the use of laxative waters,* and spare diet,50 and flannel dress. If by examina- tion we discover any alteration in the shape, size, or sen- sibility of the womb, the most effectual treatment we can have recourse to, is the daily use of from two to three drachms of sulphas potasse cum sulphure; and if this lose its laxative effect, one or more aloetic pills may be added. The warm sea-water bath every night is likewise of great service. When there is much sense of throbbing, heat, or pain about the pelvis, cupping glasses applied to the back are of service, and the patient should keep in a horizontal posture as much as possible. When the disease has ev idently taken place, we must still persevere in the same plan, and avoid such causes as excite action in general, for the longer we can keep a scirr- hus from going into a state of activity and inflammation, the longer do we keep the disease at bay. It is therefore scarcely necessary to add, that if the patient be married she must not sleep with her husband. We keep the parts clean, by inject- ing tepid water, or decoction of camomile with hemlock or opium; allay pain by anodynes; attend to the state of the bowels; and coriect stomachic affections by bitters, and other suitable remedies. Mercury, iron, arsenic, sarsaparilla, aconitum, cicuta, &c. have been given internally, but have seldom a good effect. It has been proposed to produce, with an extracting instrument, a prolapsus uteri, and then cut off the protruded womb; hut this operation is not likely to be resorted to. * Rocderer relates a case where scirrhous swelling was cured by keeping the bowels open, and giving every third evening, from ten to twenty grains of calomel.—Haller Disp. Med. Tomus IV. p. 670. 84 § 28. TUBERCLES. Tubercles are common in the uterus, insomuch that M. Bayle says, that in seven months he met with fourteen cases. They consist at first of fleshy matter, but in process of time become more like cartilage, or even bony, especially on their surface.* On examining the tumour, it is sometimes found to be intersected with membranous divisions; and a section always exhibits a pretty compact granulated surface without vessels. A tubercle may take place in one spot, and all the rest of the uterus may be healthy, and nearly of the natural size. The magnitude of the tubercle is very variable, and it may either project on the outer surface, or within the cavity of the womb; and in this last case, the adhesion to the sur- face of the cavity is generally slightf after the tubercle has fully projected. In this it differs, even in its most detached state, from polypus, which is attached not by cellular sub- stance, but by a pedicle. Sometimes there are a great many tubercles, which are found in various stages of projection, and the uterus may become greatly enlarged, and very irre- gular externally.:}: I have never seen the tubercle end in ulcer- ation, nor the substance of the uterus, although thickened, have abscess formed in it. The effects of this disease are chiefly mechanical and often altogether trifling; at other times, we have a pain in the hack, and sometimes in the hypogas- trium, which is swelled, hard, and irregular, if there be much enlargement of the womb, dyspeptic symptoms, leucorrhoea, and at length feverishness and gradual loss of strength. The progress is generally slow, unless the cervix uteri, which is always sound with regard to this disease, be affected with phagedena or cancer, or unless simple inflammation be ex- cited by pressure on some neighbouring part. Sometimes one or more tubercles are thrown off, with pains like those of labour. * Sandifort Obs. Anat. Path. lib. I, cap.viii.—Bayle in Jour, de Med. Tome V.—Murray de Osteosteamate, p. 14. et seq. | Baillie's Morbid Anatomy, chap. xix. $ I have found the uterus as large as a child's head of a year old, with manv projections and tubercles.—Peyer has a similar case, P?rerg. Anat. p. 131. 85 Menstruation may be rendered irregular, but sometimes continues unaffected. In the very last case I saw, the size of the womb was large, and two thick hard ridges could be felt in the abdomen, extending obliquely up by the sides of the umbilicus. The lower and anterior part of the womb was large, and filled the brim of the pelvis like a child's head; whilst near the promontory of the sacrum, the os uteri was felt healthy though compressed. This woman had no com- plaint except what proceeded from bulk; the bladder contrary to expectation, was not in any degree affected; the stools easy, and menstruation regular. This disease can only be confounded with diseased ovarium, but it is harder when felt through the belly, not so moveable at first, and a difference may generally be felt per vaginam. It maybe combined with tumour of the ovarium. No remedy has any power in removing the diseased sub- stance, and therefore our treatment consists in palliating symptoms, especially in attending to the bladder and bowels. We also upon general principles keep down activity, and guard against inflammatory action. The antiphlogistic regi- men should be pursued in moderation. The bowels espe- cially should be kept open, and every source of irritation removed. The tepid bath is useful. Women may live a long time, even although these tumours acquire considerable magnitude. Sometimes the whole uterus is a little enlarged, and changed into a white cartilaginous substance, with a hard irregular surface; or it may be enlarged and ossified,31 and these ossi- fications may take place even during pregnancy.* Steato- matous or atheromatous tumours of various sizes, j- or sarco- matous^: or scirrhus-like§ bodies, may be attached to the uterus. All these diseases sometimes at first give little trouble. • Vide Observ. on Abortion, 2d. edition, p. 37. f Vide Rhodius, cent. HI. ob. 46.—Bcehtner Obs. Anat. fasc. 2d.—Stoll Ra- tio Med. part. II. p. 379. jVide Friedus, in Sandifort's Observ. lib. I. c. viii. and a case by Sandifori himself, where the tumour adhered by a cord, lib. IV. p. 113. § Beader Obs. Med. ob. 29. p. 170. 86 Even their advanced stage has no pathognomonic mark, by which they can be discovered, as they produce the usual effects of uterine irritation. I must also add, that they are very little under the power of medicine. The most we can do, is to palliate symptoms; by which, however, we greatly melio- rate the condition of the patient. § 29. SPONGOID TUMOUR. The uterus is more frequently affected with spongoid tu- mour than is supposed; many cases of that disease passing for cancer. This is a firm, but soft and elastic tumour, the substance of which bears some resemblance to brain, and contains cysts of different sizes, filled with red serum or blood, or bloody fungus according to circumstances. There is no certain way of distinguishing or discovering this dis- ease in its early stage, for it often gives very little trouble, and any symptoms which do occur, are common to other diseases of the womb. The tumour, however, enlarges, and can at length be felt through the abdominal parietes. It is soft and elastic, and on the first application of the hand, feels very like a tense ventral hernia. There may be two or more tumours of unequal sizes in different parts of the belly, which can be felt to have a conncctioij with each other and may frequently be traced to the pubis. Per vaginam, the state varies in different cases; but by pressing on the external tumour at the same time, we discover its connec- tion with the womb below. We may find ulceration, or the os uteri soft, and tumified, and opened, or the posterior lip may be lost in a soft elastic tumour, and quite obliterated, whilst the anterior one, after a pretty careful examination, is felt high up, and apparently sound. Pressure seldom gives pain, till ulceration is about to take place, and no blood is usually observed on the finger after examination, unless a fungus has protruded. So far as I have seen, fluor albus is a rare attendant on this disease in the early stage, and little inconvenience is at that period produced, except what results from pressure on the bladder, causing strangury 87 or suppression of urine, attended with fits of considerable pain, like those excited by a stone. The complexion is sal- low, but the health is tolerably good, till ulceration or in- flammation take place. Ulceration may happen in different parts ; lFmay be directed to the vagina, and then we have foetid bloody discharge, or sometimes considerable hemorr- hage, and ultimately the bladder or rectum are involved in the destruction : or bloody fungus may protrude from the exterior surface of the uterus into the general cavity of the abdomen, and at length the bowels become inflamed and glued together: or the tumour may adhere to the parietes of the abdomen, and the skin after becoming livid gives way, and a fungus shoots out from the belly. As the disease advances towards ulceration, the health is more impaired, hectic fever takes place, and the patient is ultimately cut off. The whole treatment, I am sorry to say, consists in pal- liating such sympathetic or local symptoms as may arise in the course of the disease. [§ 30. CAULIFLOWER EXCRESCENCE FROM THE OS UTERI. Dr. John Clarke of London, considers himself as the first writer who has taken notice of this disease. The cauliflower excrescence, according to him, arises al- ways from some part of the os uteri. As several of the early symptoms are not very distressing to the patient, the tumour in the beginning is rarely the subject of medical attention. The first changes of structure have therefore not been ob- served. In general the tumour is not less than the size of a blackbird's egg. At this period it makes an irregular pro- jection, and has a base as broad as any other part of it, attached to some part of the os uteri. The surface has a granulated feel, considerable pressure on handling it, does not occasion any sense of pain. The remainder of the os uteri, will at this period, be found to have no sensible altera- tion of structure. By degrees more and more of the circle ot the os uteri, and the external part of the cervix uteri, become 88 affected with the same morbid alteration of slruct.iiv, till at length the whole is involved in the disease. The growth is in some cases slow, but in others rapid, so that in the course of nine months, it will sometime^cntirely fill up the cavity of the pelvis, and block up the entrance of the vagina. As the bulk of the tumour increases, the granulated struc- ture becomes more evident, and is found to resemble very much the structure of the cauliflower, when it begins to run to seed. In most cases it is of a brittle consistence, so that small parts of it will come away, if it be touched too rudely; and such pieces appear to be very white. Sometimes, though no violence has been used, small portions of a white sub- stance come away with the urine of the patient, and in the discharge from the vagina. When the tumour has arrived at a size greater than that of the os uteri, it spreads very much, and as the base is the smallest part of the tumour, persons, not conversant with the disease, have often mistaken it for polypus. A little at- tention however, to the feel of the tumour, and the breadth of its base, will be sufficient to distinguish them. In the very early state of the cauliflower excrescence, a discharge from the vagina takes place like fluor albus ; it very soon becomes thin and watery, and is sometimes tinged with blood. In most cases upon coming away, it is apparently as thin and transparent as pure water; but the linen on which it is received, when dry becomes stiff, as if it had been starched. The quantity of the discharge when the excres- cence is large, will sometimes be sufficient to wet thoroughly, ten or twelve napkins in a day. Now and then a discharge of pure blood occurs. When this ceases the discharge of thin transparent fluid re-appears. An offensive odour generally accompanies the discharge, which is greatest when there has lately been an evacuation of pure blood, or of the cata- menia. Mucus has sometimes been found in the fluid dis- charged, but pus never. Patients labouring under this disorder, are variously af- fected with regard to pain. In the commencement none is 89 felt; but during its progress pain is in some cases experi- enced. Generally in the advanced stage, the patient feels pain in the back, and in the direction of the round ligaments of the uterus. The pain is not described to be lancinating, as in cancer, and is without any sensible aggravation by paroxysms; but on the whole, it is most felt after the patient has been in a perpendicular attitude. The disease attacks indiscriminately women of all ages. The patient is destroyed by the debility occasioned by the profuse discharge ; and in the course of the disease, she al- ways becomes extremely emaciated from the above cause. It always terminates fatally. Respecting the treatment of this disease, nothing satisfactory can be offered. All stimu- lating substances either in diet or medicine, seem to aggra- vate it, by increasing the discharge; and no astringents in- ternally given appear to lessen it. The only means from which any benefit has been derived, is the injecting into the vagina three times a day, a strong decoction of cortex gra- nati, or of cortex quercus, in which alum is dissolved in the proportion of eight or ten grains to every ounce of it. This has the double effect of lessening the quantity of the dis- charge, and rendering it less offensive. The use of anodynes must be resorted to for the mitigation of pain, and the occa- sional symptoms of suppression of urine, and costiveness, are to be relieved by the use of a catheter and mild laxa- tives.^)] § 31. CALCULI. Earthy concretions are sometimes formed in the cavity of the uterus, and produce the usual symptoms of uterine irritation; and Vigarous considers them as very apt to excite hysterical affections. As in the bladder of urine, the con- stant presence of a calculus tends to thicken its coats; so the (s) Vide a paper on the Cauliflower excrescence from the os uteri, &c. by John Clarke, M. D. Transact, of a Society for the improvement of Medical and Chirurgical knowledge, 1812. And new Medical and Physical Journal, July, 1812. VOL. I. * 90 irritation of a stone in the uterus can excite a disease of the substance of the womb, and produce ulceration, which may extend to the rectum. The disease in question is very rare, and can only be discovered by feeling the concretion with the finger, or a probe introduced within the os uteri, which is sufficiently open to permit of this examination. Nature, it would appear, tends to expel the substance,52 and we ought to co-operate, if necessary, with this tendency. We must also relieve suppression of urine,* or any other urgent symp- tom which may be present. § 32. POLYPI. Polypous tumours are not uncommon, and may take place at any age; they are not, however, often met with in very young women. They always affect the health, producing want of appetite, dyspeptic symptoms, uneasiness in the ute- rine region, a variable swelling of the abdomen, aching pain in the back, bearing-down pains, tenesmus, and a dragging sensation at the groins. When these symptoms have con- tinued some time, the strength is impaired, and the pulse be- comes more frequent. At first, there is generally a mucous discharge; but at length blood is discharged, owing to the rupture of some of the veins of the tumour} or sometimes from the uterine vessels themselves and the permanent dis- charge not unfrequently becomes foetid. Mr. Clark, in his late work, very properly notices, that the blood often coagu- lates over the polypus, and comes off like a ring. These symptoms, however, cannot point out, to a certainty, the existence of a polypus: we must have recourse to examina- tion, by which we discover that the uterus is enlarged, its mouth open, and a firm, but generally, moveable body within it. If the os uteri have not yet opened so as to admit the finger, the diagnosis must be incomplete. By degrees the polypus descends from the uterus, or pain- ful efforts are made more quickly to expel the tumour, the • This proved fatal in a child of five years old 91 body of which passes into the vagina53, and sometimes occasions retention of urine.54 The pedicle remains in utero, and the bad consequences formerly produced still continue, except in a few cases, where the tumour has dropped off,* and the patient got well. In such cases, it has been sup- posed that the os uteri acted as a ligature; and to the same cause is attributed the bursting of the veins, which produce, in many instances, copious hemorrhage. But although hemorrhage be most frequent after the polypus has descend- ed, yet it may take place whilst it remains entirely in utero. It sometimes happens that the uterus becomes partially inverted,! before or after the polypus is expelled into the vagina; and this circumstance does not seem to depend al- together on the size of the polypus, or its weight. Polypus may also be accompanied with prolapsus uteri.:}: Polypi may be attached to any part of the womb, to its fundus, cervix, or mouth ; and it has been observed, that there is less tendency to hemorrhage, when they are attach- ed to the cervix, than either higher up, or to the os uteri it- self. If there be an union betwixt the os uteri and the tu- mour,§ or if they be in intimate contact, polypus, may pass for inversio uteri; but the history of the case, and attentive examination, will point out the difference, which will be no- ticed when I come to consider inversion and prolapsus of the uterus. Here I may only remark, that the womb is sensi- ble, but the polypus is insensible to the touch, or to irrita- tion ; but it should be recollected, that if the polypus be moved, sensation can be produced by the effect on the womb. Polypi are of different kinds. The most frequent kind is of a firm semicartilaginous structure, covered with a produc- tion of the inner membrane of the womb; and indeed it seems to proceed chiefly from a morbid change of that mem- * Mem. de l'Acad. de Chir. Tom. m. p. 552 f Vide case by Goulard, in Hist, de l'Acad. de Sciences, 1732. p. 42.—-Dr. Denman, in his engravings, gives two plates of inversion, one from Dr. Hun- ter's Museum, the other from Mr. Hamilton. % Med. Comment. Vol. IV. p. 228. «j Mem. of Med. Society in London, VoL V. p. 12. 92 brane, and a slow subsequent enlargement ol the diseased portion; for the substance of the uterus itself is not nece> sarily affected. The enlargement is generally greatest at the farthest extremity of the tumour, and least near the womb; so that there is a kind of pedicle formed, which some- times contains pretty large blood vessels, and the tumour is pyriform. But if the membrane of the uterus be affected to a considerable extent, and especially if the substance of the uterus be diseased, then the base, or the attachment of the polypus, is broad. The vessels are considerable, especially the veins, which sometimes burst. In every instance, I believe, if the patient live long, the tumour is disposed to ulcerate. The ulcer is either superficial and watery, or it is hollowed out, glossy, and has hard margins, or it is fungous. The two last varie- ties are most frequent. Some polypi are soft and lymphatic, but these are rare in the uterus. Some are firm without, but contain gelatinous fluid, or substance like axunge within. Some are solid, others cellular, with considerable cavities. Polypi are hurtful at first, by the irritation they give the uterus, and by sympathetic derangement of the abdominal viscera. In a more advanced stage, they are attended with debilitating and fatal hemorrhage, and often with febrile symptoms, especially if the discharge be offensive, or the surface ulcerated. Notwithstanding the existence of polypus, however, it is possible for a woman to conceive.* Various means have been proposed for the removal of polypi, such as excision, caustic, or tearing them away; but all of these are dangerous and uncertain ; and therefore the only method now practised, is to pass a ligature round the base or footstalk of the polypus, and tighten it so firmly as to kill the part. The ligature consists of a firm silk cord, or a well twisted hemp string, properly rubbed with wax, or covered with a varnish of elastic gum. This is better than * In M. Guiot's case, the polypus was expelled.—M. Levret adds other cases, Mem. de l'Acad. de Chir. Tom. HI. p. 543. 93 a silver wire, which is apt to twist or form little spiral turns, which impede the operation, and may cut the tumour. It is difficult to pass the ligature properly, if the polypus be alto- gether in utero ; and it ought not even to be attempted, if the os uteri be not fully dilated. On this account, if the symp- toms be not extremely urgent, it is proper to delay until the polypus have wholly, or in part, descended into the vagina; and when thte has taken place, no good, but much evil may result from procrastination. It has even been proposed to accelerate the descent of the polypus, and produce an inver- sion of the uterus.* A double canula has been long employed for the purpose of passinrr the ligature, one end of which was brought through each tube; and the middle portion forming a loop, was car- ried over the tumour, either with the fingers, or the assist- ance of a silver probe with a small fork at the extremity. By practice and dexterity, this instrument may doubtless be adequate to the object in view; but without these requisites, the operator will be foiled, the ligature twisting or going past the tumour, every attempt giving much uneasiness to the patient, and not unfrequently, after many trials and much irritation, the patient is left exhausted with fatigue, vexation, and loss of blood. This is very apt to happen, if the polypus be so large as to fill the vagina. The process may be facili- tated by employing a double canula, but the tubes made to separate and unite at pleasure,! by means of a connecting base, or third piece, which can be adapted to them like a sheath. The ligature is passed through the tubes, which are to be placed close together, and no loop is to be left at the mid- dle. They are then to be carried up along the tumour, gene- * M. Baudelocque observes, " Nous regardions ce renversement neces- saire pour obtenir la guerison de la malade." Recueil Period. Tome IV. p. 137. f An instrument of this kind is proposed by M. Cullerier, and is described ■ by M. Lefaucheux in his Dissert, sur lesTumeurs circonscrites et indolentsdu tissu cellulaire de lamatrice et du vagin.(*) (0 For a plate and description of this instrument, the reader is referred to Cooper's Surgery, Philadelphia edition. 94 ually betwixt it and the pubis. Being slid up along the finger to the neck of the polypus, one of them is to be firmly retained in its situation by an assistant, and the other carried com- pletely round the tumour, and brought again to meet its fel- low. The two tubes are then to be united by means of the common base. The ligature is thus made to encircle the polypus, and, if necessary, it may afterwards be raised higher up with the finger alone, or with the assistance of a forked probe. When the ligature is placed in its proper situation, it is to be gradually and cautiously tightened, lest any part of the uterus which may be inverted be included. If so, the patient complains of pain, and sometimes vomits; and if these symp- toms were neglected, and the ligature kept tight, pain and tension of the hypogastrium, fever and convulsions would take place, and in all probability the woman would die.*5 In some instances, however, the womb has been included with- out a fatal effect.56 Even when the uterus is not included, fever may succeed the operation, and be accompanied with slight pain in the belly; but the symptoms are mild, and no pain is felt when the ligature is first applied. If the first tightening of the ligature, by way of trial, give no pain, it is to be drawn firmly, so as to compress the neck of the tumour sufficiently to stop the circulation. It is then to be secured at the extremity of the canula; and as the part will become less in some time, or may not have been very tightly acted on at first, the ligature is to be daily drawn tighter, and in a few days will make its way through. After the polypus is tied, it is felt to be more turgid, and harder; and if visible, it is found of a livid colour, and presently exhales a foetid smell. These are favourable signs. The diet is to be light, and all irritation avoided during the cure. The bowels and bladder must be attended to, and if there be sympathetic irritation of the stomach, soda water is useful, with small doses of laudanum.{w) (k) The reader is referred to the following interesting paper on the subject of the preceding article, viz, " Memoir sur l'organization des Polypes Uterins 95 § 33. MALIGNANT POLYPE. There are other tumours still more dangerous,* as they end in incurable ulceration, and are so connected with the womb, that the whole of the diseased substance cannot be removed. These always adhere by a very broad base,57 and cannot be moved freely, or turned round like the mild polypus. They are sometimes pretty firm, but generally they are soft and fungous, or may resemble cords of clotted blood. When dissected, they are found to be very spongy, with cells or cavities of various sizes; sometimes they are laminated. These, which have been called vivaces by M. Levret, are always the consequenee of a diseased state of the womb; but they are not always, as that author supposes, vegetations from an ulcerated ■ surface. They do, however, very frequently spring from that source, being generally of the spongoid nature. Occasionally they have been mistaken for a piece of a retained placenta, and portions of foetid fungi have been torn away, in attempts to extract the supposed placenta, or ovum. The hypogastric region is tumid, and painful to the touch, even more so than the tumour itself, which, felt per vaginam, is less sensible than the womb. Sometimes little pain is felt in this disease, except when the womb is pressed. The tu- mour often bleeds, discharges a sanious matter, and may shoot into the vagina: but in this it differs from polypus, that it comes into the vagina generally by growth, and not by ex- pulsion from the womb, which does not decrease or become empty as the vagina fills. The treatment must be palliative, for extirpation does not succeed, the growth being rapidly renewed. Opiates and cleanliness are most useful. et ^application de cette connoisance a la pratique chirurgicale, par P. J. Roux in tome 3ieme des OZuvres chirurgicales de P. J. Desault par Xav. Bichat. p. 370. * Vide Mem. de l'Acad. de Chir. Tome III. p. 588—Herbiniaux Observa- tions, Tome Lob. 39.—Baillie's Morbii Anatomy, eaap. xix—Vigarous dc Malad, des Femmes, Tome I. p, 42 5. 96 § 34. MOLES.. Moles* are fleshy or bloody substances contained within the cavity of the uterus. They acquire different degrees of magnitude, and are found of various density and structure." They may form in women who have not borne children,! or they may succeed a natural delivery,^ or follow an abortion, or take place in a diseased state of the uterus.§ It is the opinion of many, that these substances are never formed in the virgin state, and no case that I have yet met with contradicts the supposition. The symptoms produced by moles are at first very much the same with those of pregnancy, such as nausea, fastidious appetite, enlargement of the breasts, &c.; buf the belly enlarges much faster, is softer, and more variable in size than in pregnancy, being sometimes as large in the se- cond month of the supposed, as it is in the fifth of the true pregnancy. Pressure occasionally gives pain. Petit ob- serves, that the tumour seems to fall down when the woman stands erect, but this is not always the case. It must be con- fessed, that the symptoms are at first, in most cases, ambigu- ous, nor can we for some time arrive at certainty. In ge- neral, the mass is expelled within three months, or before . the usual time of quickening in pregnancy; and more or less hemorrhage accompanies the process, which is very si- milar to that of abortion, and requires the same manage- ment. || Sometimes the expulsion may be advantageously hastened, by extracting the substance with the finger; but we must be careful not to lacerate it, and leave part behind. If the mole be retained beyond the usual time of quickening, * Sandifort Obs. Path. Anat. lib. II. p. 78.—Schmid. de Concrement. Uteri, in Haller's Disp. Med. Tomus IV. p. 746. f La Motte, chap. vii. Tliis chapter contains several useful cases, one of which proved fatal from hemorrhage. * Hoffman. Opera, Tomus, III. p. 182.—Stahl. Coleg. Casuale, cap. Ixxvi. p. 797. «s With scirrhus of the uterus, Haller's Disp. Med. IV. p. 751 et 753. # || Puzos advises blood letting, Traite, p. 211.—Vigarous recommends eme- tics and purgatives, to favour the expulsion, Tome I. p. 115. 97 we find that the belly does not increase in the same propor- tion as formerly, and the womb does not acquire the magni- tude it possesses in a pregnancy of so many months stand- ing. There is also no motion perceived. Many of the symp- toms of mole may proceed from polypus; but in that case, the breasts are flaccid and the symptoms indicating preg- nancy are much more obscure. The os uteri is not neces- sarily closed in a case of polypus; whereas in that of a mole, if there have been no expulsive pains, it is generally shut. When a woman is subject to the repeated formation of moles, I know of no other preventive, than such means as im- prove and invigorate the constitution in general, and the ute- rus in consequence thereof. This is of no small importance, as a weak state of the uterine system predisposes to more for- midable diseases, and may be followed by scirrhus of the womb or of the breast. § 35. HYDATIDS. Hydatids may also enlarge the womb, and these frequently are formed in consequence of the destruction of the ovum at an early period,59 or of the retention of some part of the pla- centa, after delivery or abortion. We possess no certain di- agnostic : when they are formed in consequence of coagula, or part of the placenta remaining in utero, the symptoms must be such as proceed from the bulk of the womb, or from its irritation, as if by a polypus or mole. The remarks in the preceding section are therefore applicable here; but in a great majority of cases, hydatids are formed in consequence of the destruction of an ovum; and accordingly, the symp- toms at first are exactly the same with those of pregnancy. These cease when the ovum is blighted, and the time when this happens is marked by the breasts becoming flaccid, and the sickness and the sympathetic effects of pregnancy going off. The conception remains, and the belly either continues nearly of the same size, or, if it increase, it is very slowly. Menstruation does not take place; but there may occasion- ally be discharges of blood in different degrees, and there vol. I. o 98 always is at one period or other, a very troublesome discharge of water, so that cloths are required, and even with these, the patient is uncomfortable. No motion is perceived by the woman, and the size of the belly and state of the womb do not correspond to the supposed period of pregnancy. In some instances, the health does not suffer; in others, feverishness and irritation are produced. After an uncertain lapse of time, pains come on, and the mass is discharged, often with very considerable hemorrhage. This expelling process may some- times be advantageously assisted by introducing the hand to remove the hydatids, or to excite the contraction of the womb; but this must be done cautiously, and only when hemorrhage or some other urgent symptoms occur. These must be treat- ed on general principles. In some cases, milk is secreted after the hydatids are ex- pelled. In others, a smart fever, with pain in the hypogas- trium, follows. It requires laxatives and fomentations. When hydatids form in a blighted ovum, their number varies greatly in different cases. In some, I have seen only a little bit con- taining vesicles, often only the under part which had been for some time detached in a threatened abortion. In others, al- most the whole is changed, and the mass much enlarged. This, I presume, is connected with jthe womb, by the un- changed portions alone; and therefore, in examining the in- ner surface of such a uterus after the mass was expelled, we should expect to find it more or less similar to the gravid state, according to the greater or less change in the ovum. The re- lative magnitude of the vessels in the two states has not been ascertained, few opportunities being afforded of dissection in this disease, (a;) (x)Ruysch in the first volume of his valuable works, has given two very curious and accurate plates of these hydatids of the placenta or uterus. There is also a representation of these vesicles in Baillie's plates of Morbid Anatomy, executed with great truth and elegance. It is now generally con- sidered by naturaUsts, that the hydatids found in the human body, are a sort of imperfect animals; and as Dr. Bailhe has observed, although there may be some difference between them in simplicity of organization, this need be no considerable objection to the opinion, as life may be conceived to be at- tached to the most simple form of organization. 99 Sometimes there is only one large hydatid, or, at most, a very few in the womb, and the preceding remarks will also be applicable, hi a great measure, to this case. In the ad- vanced stage, we find the belly swelled, as in pregnancy; but the breasts are flaccid, and no child can be discovered in utero, nor does the woman perceive any motion. There may be pain in the abdomen, and obscure fluctuation is discernible. The neck of the womb is small, and the case much resembles ovarian dropsy, except that the tumour occupies the region of the uterus. The duration of this complaint is uncertain; but the water is at last discharged suddenly, and after making some exertion. The bag afterwards comes away, and the process is not attended with much pain.* It is most prudent to be patient; but if the symptoms be troublesome, the fluid can be drawn off by the os uteri. This disease, a solitary hydatid, is oftener combined with pregnancy, or with a mole, than met with alone. The first combination60 is not uncom- mon, and I have seen the hydatid expelled some weeks before labour. Hildanus gives an instance of the second, where the ovum was converted into a mole intimately connected to the uterus, and complicated with a collection of fluid to the extent of six pounds. In this case, so much irritation was given, as to exhaust the strength, and produce local inflam- mation. § 36. AQUEOUS SECRETION. A different disease from that described in the last section, is an increased Secretion from the uterus itself, accompanied generally with symptoms of uterine irritation; and if the wo- man menstruate, the menses are pale and watery. There may For further information on the subject of hydatids, particularly those of the uterus, the student is referred to a paper by the editor, inserted m the Eclectic Repertory, Vol. I. p. 499, and seq. Also to Monro's Morbid Anato- my of the human gullet, stomach and intestines. Edin. 1811. p. 255. * Hildanus, I think, relates the history of a woman who was supposed to be pregnant, but, dwn nactu (urn maritt rem haberet, a sudden inundation swept away her hopes. 100 be a constant stillicidium of water,* or from some obstructing cause the fluid may be for a time retained,6* and repeatedly discharged in gushes; I do not know to a certainty, that this can take place without some organic affection of the womb, or some substance within its cavity. At the same time, I have met with this where no hydatids were discharged, where the womb felt sound, and a cure was at last accomplished. We must always examine carefully, for it may proceed from hyda- tids, or from disease, or excrescences about the os uteri. If nothing can be discovered, we must proceed upon the general principle of improving the health, and injecting mild astrin- gents. I need scarcely caution the practitioner not to con- found a discharge of urine from an injury of the bladder, with this complaint.,f , § 37. WORMS. Worms:}: have been found in the uterus, producing consi- derable irritation; and generally, in this case, there is a foe- tid discharge. We can know this disease only by seeing the worms come away. It is cured by injecting strong bitter in- fusions. ■ . § 38. TYMPANITES. Sometimes^ air is secreted by the uterine vessels, and comes away involuntarily, but not always quietly. Tonics, and astringent injections, occasionally do good; and as this * Hoffman mentions a woman who had a constant stillicidium, a pint being discharged daily. It at last proved fatal. Opera, Tom. III. p. 326, and Tom. I. p. 330. ■j- Vesalius, Tom. I. p. 438, says, that he found an uterus containing 180 pints of fluid, and its sides in many places scirrhous. I wish he may not have mistaken the ovarium for the womb. * Vigarous Malad. Tome I. p. 412.—Mr. Cockson mentions a case, where maggots were discharged before the menstrual fluid. The woman was cured, by injecting oil, and infusion of camomile flowers. Med. Comment. Vol III. p. 86. § Vide Vigarous' Maladies, Tome I. p. 401. 101 disease rarely causes sterility, it is sometimes cured perma- nently by pregnancy. It is said, that the air is, in certain cases, retained, and the uterus distended with it, producing a tympanites of the uterus. § 39. PROLAPSUS UTERI. The prolapsus, or descent of the uterus, takes place in va- rious degrees.* The slighest degree, or first stage has been called a relaxation ; a greater degree, a prolapsus; and the protrusion from the external parts, a procidentia. It is ne- cessary to attend carefully to this disease, to ascertain its existence, as it may, if neglected, occasion bad health, and many uneasy sensations. The symptoms at first, if it do not succeed parturition are ambiguous, as some of them may proceed from other causes. They are principally pain in the back, groins, and about the pubis, increased by walking, and accompanied with a sensation of bearing-down. There is a leucorrhseal discharge, and sometimes the menses are increas- ed in quantity. In a more advanced state, there is stran- gury, or the urine is obstructed, and the patient feels a tumour or fulness toward the orifice of the vagina, with a sensation as if her bowels were falling out, which obliges her instantly to sit down, or to cross her legs as if to prevent the protrusion. This is accompanied with a feeling of weakness. There are also, during the whole course of the complaint, but especially after it has continued for some time, added many symptoms, proceeding from deranged action of the stomach and bowels, together with a variety of those called nervous. On this account, an inattentive practitioner may obstinately consider the case as altogether hysterical, until emaciation and great debility are induced. But if the woman have been recently delivered, there is less likelihood of the practitioner being misled. She feels a weight and uneasiness about the pubis and hypogastric re- gion, with an irritation about the urethra and bladder ; and * Vide Memoir by Sabaticr, in 3d. Vol. of the Memoirs of the Academy of Surgery. iOS sometimes a tenderness in the course of the urethra, or about the vulva. A dull dragging pain is felt at the groins, and when she stands or walks, she says she feels exactly as she did before the child was born, or as if there were something full and pressing. Pains are felt in the thighs, and the back is generally either hot, or aches. These symptoms go off in a great measure, when she lies down, though, in some cases, they are at first so troublesome, as to prevent rest. In some instances, no pain is felt in the back; but whenever the pa- tient stands, she complains of a painful bearing-down sensa- tion, or sometimes of pressure about the urethra, or orifice of the vagina. By examination, the uterus is felt to be lower down than usual, and the vagina always relaxed. In certain circum- stances, it prolapses, forming a circular protrusion at the vulva. Next, the 03 uteri descends so low as to project out of the vagina. In the greatest degree, or procidentia, the uterus is forced altogether out, inverting completely the vagina, and forming a large tumour betwixt the thighs. The intestines descend62 lower into the pelvis, and even may form part of the tumour, being lodged in the inverted vagina, giv- ing it an elastic feel. In some instances, this unnatural situation of the bowels gives rise to inflammation. The uterus is partially retroverted, for the fundus projects immediately under the perinseum, and the os uteri is directed to the an- terior part of the tumour. The orifice of the urethra is sometimes hid by the tumour, and the direction of the canal is changed; for the bladder, if it be not scirrhous, or distend- ed with a calculus of large size, is carried down into the pro- truded parts*3; and a catheter passed into it, must be direct- ed downwards and backwards. The procidentia is attended with the usual symptoms of prolapsus uteri, and also with difliculty in voiding the urine, tenesmus, and pain in the tumour. If it have been long or frequently down, the skin of the vagina becomes hard, like the common integuments, and it very rapidly ceases to secrete. Sometimes the tumour inflames, indurates, and then ulceration or sloughing takes place. This procidentia may occur in consequence of ne- 103 glecting the first stage, and the uterus is propelled with bearing-down pains; or it may take place all at once, in consequence of exertion, or of getting up too soon after de- livery. It may also occur during pregnancy, and even dur- ing parturition. Sometimes it is complicated with stone in the bladder,64 or with polypus in the uterus.* Some have, from theory, denied, the existence of prolap- sus,6* and others have disputed wiiether the ligaments were torn or relaxed. There can be little doubt, that when it oc- curs speedily after delivery, it is owing to the weight of the womb, aud the relaxed state of the ligaments and vagina. From these causes, getting up too soon into an erect posture, or walking, may occasion prolapsus, particularly in those who are weak or phthisical. When it occurs gradually in the un- impregnated state, it is rather owing to a nclaxation of the va- gina, and parts in the pelvis, than elongation of the round ligaments. By experiments made on the dead subject, we find, that more resistance is afforded to the protrusion, by the connection of the uterus and vagina to the neighbouring parts, than by the agency of the ligaments; for although the ligaments be cut, we cannot, without much force, make the uterus protrude. Frequent parturition, fluor albus, dancing during menstruation, and whatever tends to weaken or relax the parts, may occasion prolapsus. Sometimes a fall brings it on. No age is exempt from it.66- When symptoms indi- cating prolapsus uteri manifest themselves, we ought to ex- amine the state of the womb, the patient having lately been, or rather being, in an erect posture. The symptoms some- times at first turn the attention rather to the bladder or pubis, than the womb; but a practitioner of experience will think it incumbent on him to ascertain the real situation of that viscus. If we find that there is a slight degree of uterine descent, we must immediately use means to remove the relax- ation. These consist in the frequent injection of solution of sulphate of alumin, either in water, or decoction of oak bark, repeated ablution with cold water, tonics, and the use of the • Vide the case of a girl aged twenty-one years, related by Mr. Pynney. The polypous excrescence was extirpated from the os uteri, and then a pes- sary was employed^ Med. Comment. Vol. IV. p. 228. 104 cold bath, at the same time that the bowels are kept regular, all exertion avoided, and a recumbent posture much observed. If these things fail, or if the disease exist to a considerable de- gree, then, besides persisting in them, we must have recourse to the assistance of mechanical means. These consist of sup- porting substances called pessaries, which are placed in the vagina, and resting on the perinseum, keep up the womb. They always give immediate relief, but where the relaxation is considerable, they only mitigate, but do not entirely re- move the sensation, which must continue more or less, as long as the relaxation remains. In recent cases, or where the relaxation is not great, a perseverance in the use of the pessary, topical astringents and general tonics may accom- plish a cure. Fatigue or exertion must always be avoided. Pessaries are made of wood, and are of different shapes, some oval, some flat and circular, some like spindles, or the figure of eight, others globular. Of all these, the globular(t/) pessary is the best, and it ought to be of such size as to re- quire a little force to introduce it into the vagina; that is to say, it must be so large as not to fall through the orifice, when the woman moves or walks. Whatever be employed, it ought to be taken out frequently, and cleaned.67 By di- minishing gradually the size of the pessary, and using astrin- gents, we may often be able at last to dispense with it. In all the stages, a firm broad bandage applied round the abdomen, frequently relieves the uneasy sensations about the bowels, hack, and pubis. The cold bath is also useful. It is farther necessary to mention, that the symptoms and treatment of prolapsus may be modified by circumstances which precede it, but with which, it is not essentially connected. For in- stance, a tender or inflamed state of the uterus, and the. ap- pendages, may take place after delivery, and when convales- cent, the patient may rise too soon, or sit up, striving to make the child suck, and thus bring on a degree of prolapsus. In this case, it is evident that the symptoms may be more acute or painful, and they will not be removed by a pessary, until (#) The oval form is nevertheless preferred by many, and apparently not without reason. 105 by continued rest, laxatives, and occasional fomentations, the morbid sensibility of the parts within the pelvis be got rid of. When the relaxation is great, it has been proposed to use a hollow elliptical pessary, so large, as that by pressing against the sides of the vagina, it may support both itself and the womb, but it generally gives pain, and the relaxed vagina, turns up within it, and becomes irritated. I am therefore, clearly of opinion, that the oval pessary should, though hollow, have no large aperture. The long diameter must vary from 2* to 3* inches, according to the degree of relaxation. In such cases of relaxation, if the oval pessary do not succeed in removing the distressing sensation of the abdominal viscera being about to fall out, then, in addition to it or the globe pessary, benefit may be derived from sup- porting the perineum itself, with a soft pad, with a spring on a similar principle with that used for prolapsus ani. A contrivance of this kind, or a firm T-bandage must be em- ployed with a globe pessary, where the perineum is greatly lacerated. (») If a procidentia be large, and have been of long duration, the reduction of the uterus may disorder the contents of the abdomen, producing both pain and sickness. In this case, we must enjoin strict rest in a horizontal posture. The belly should be fomented, and an anodyne administered. Sometimes it is necessary to take away a little blood; and we must always attend to the state of the bladder, preventing an accumulation of urine. When the symptoms are abated, (z) In my own practice, I have generally preferred the oval pessary at elastic gum, by being apphed transversely; as regards the vagina, there is less danger of impeding the evacuation of the faeces and urine, by pressure on the rectum and neck of the bladder, or urethra. Where this cannot be procured pessaries maybe made of silver, of the oval form and hollow, and with care may be found to answer. But it is probable, that the sponge pessary, under proper management, will be found to answer every intention. This kind of pessary, appears first to have been publicly recommended by Dr Haighton, of London, and has since been approved and adopted by several practitioners of respectability. See a paper on tins subject, by Mr. Dawson, in the 13th Vol. of Lend. Med Physl. Journal VOL. T. r 106 a pessary must be introduced,* and the woman may rise for a little, to ascertain how it fits ; but, as in other cases, she ought for some time to keep much in a horizontal posture, and avoid for a still longer period every exertion. If there have existed inflammation of the displaced bowels, during the continuance of the procidentia, serious consequences may result from the reduction, owing to the adhesions which have formed. Should there be much difliculty and pain at- tending the attempt to reduce, it ought not to be persisted in. If the tumour, from having been much irritated, or long protruded, be large, hard, inflamed, and perhaps ulcerated, it will be impossible to reduce it until the swelling and in- flammation are abated, by a recumbent posture, fomenta- tions, saturnine applications, laxatives, and perhaps even blood-letting.f After some days we may attempt the re- duction, and will find it useful previously to empty the blad- der. The reduction, in general, causes for a time, abdomi- nal uneasiness. If the uterus cannot be reduced, and is much diseased*, it has been proposed to extirpate the tumour. This has been done, it is true, with success,68 but it is ex- tremely dangerous ; for the bladder is apt to be tied:): by the ligature, which is put round the part; and as the intestines fall down above the uterus into the sac, formed by the invert- ed vagina, they also are apt to be cut§ or constricted. A prolapsus uteri does not prevent the woman from becom- ing pregnant ;69 and it is even of advantage that she should become so, as we thus, at least for a time, generally cure the prolapsus. But we must take care, lest premature la- bour|| be excited; for the uterus may not rise properly, or may again prolapse, if exertion be used. * Dr. Denman very properly advises, that a pessary should not be intro- duced immediately after the uterus is reduced. Lond. Med. Journal, Vol. VII. p. 56. f M. Hoin succeeded in reducing a very large, hard and even ulcerated procidentia, by fomentations, rest, and low diet. Mem. de l'Acad. de Chir. Tome m. p. 365. $ This happened in Ruysch's case. Obs. Anat. vii. «j This occurred in a case related by Henry, ab Heers. Obs. Med. p. 192 i Vide Mr. Hill's case, in Med. Qomment. Vol. IV. p. S3. 107 Sometimes, especially if the person receive a fall,70 or have a wide pelvis, the uterus may prolapse during pregnancy, although the woman have not formerly had this disease. Our first care ought to be directed to the bladder/1 lest fa- tal suppression of urine72 take place. Our next object is to replace the uterus, and retain it by rest, and a pessary. If it cannot be reduced,* the uterus must be supported by $ ban- dage,! until, by delivery, it be emptied of its contents. It is then to be reduced. The management of prolapsus during labour, will be afterwards considered. If prolapsus be threatened, or have taken place after deli- very, in consequence, for instance, of getting up too soon, we must confine the woman to a horizontal posture, till it have regained its proper size and weight; and this diminu- tion is to be assisted by gentle laxatives, particularly the daily use of the sulphas potassse cum sulphure, in doses of from two to three drachms. The bandage formerly noticed, is also useful and comfortable. In some cases, the cervix uteri lengthens and descends lower in the vagina, though the body of the womb remains in situ. This is not to be confounded with prolapsus, for it is really a preternatural growth of part of the uterus; and this portion, or elongation, has been removed by liga- ture. § 40. HERNIA. Inguinal hernia of the uterus have been long ago described by Sennert, Hildanus, and Ruysch, and very lately by Lal- lement. This species of displacement may occur in the unimpregnated state, and the woman afterwards conceive; or it may take place when pregnancy is somewhat advanced. If it be possible to reduce the uterus, this must be done; and * See a remarkable case in prolapsus in the gravid state, where the whole uterus protruded, and reduction was not accomplished till after deli- very. By P. C. Fabricius, in Haller. Disp. Chir. Tomu» HI. p. 434. f Vide Memoirs by M. Sabatier, in Mem. de l'Acad. de Chir. Tome DX p. 370. 108 in one stage, an artificial enlargement of the foramen, through which the uterus has protruded, may assist the re- duction. If however, gestation be far advanced, then the in- cision must be made into the uterus whenever pains come on,, and the child must be thus extracted. § 41. DROPSY OF THE OVARIUM. The ovarium is subject to several diseases, of which the most frequent is that called dropsy. The appellation, how- ever, is not proper, for the affection is not dependent on an increased effusion of a natural serous secretion or exhalation, but is more akin to encysted tumours, and consists in a pe- culiar change of structure,* and the formation of many cysts, containing sometimes watery, but generally viscid fluid, and having cellular, fleshy,f or indurated substance interposed between them, frequently in considerable masses. They vary in number and in magnitude. There is rarely only one large cyst containing serous fluid; most frequently we have a great many in a state of progressive enlargement; the small ones are perhaps not larger than peas, others are as large as a child's head, whilst the one which has made most pro- gress may surpass in size the gravid uterus at the full time. The inner surface of the cysts may either be smooth, or co- vered with eminences like the papillse of a cow's uterus4 Their thickness is various, for sometimes they are as thin as bladders, sometimes fleshy, and an inch thick. The fluid they contain is generally thick and coloured, and frequently foetid, and in some instances, mixed with flakes of fleshy matter, or tufts of hair; occasionally, it is altogether gela- tinous, and cannot be brought through a small opening. The * Le Dran says, this dropsy always begins with a scirrhus, and is only a symptom of it.—Dr. Hunter says he never found any part of a dropsical ova- rium in a truly scirrhous state. f Dr. Johnson's patient had the right ovarium converted into a fleshy mass, weighing nine pounds, and full of cysts. Med. Comment. Vol. VII. p. 265. + I have seen the inner surface of the ovarium studded over with nearly two dozen of large tumours. M. Morand noti'.es two cases, in which a similar structure obtained. 109 tumour has been seen made up entirely, or in part, of hydatids.73 The effects or symptoms of this disease of the ovarium, may all be referred to three sources, pressure, sympathetic ir- ritation, and action carried on in the ovarium itself. It some- times, though not often, begins with pretty acute pain about the groins, thighs, and side of the lower belly, with disturbance of the stomach and intestines, and occasionally^byncope. A few patients feel pain very early in the mammae; and M. Ro- bert affirms, that it is felt most frequently in the same side with the affected ovarium. In some cases milk is secreted.74 But generally the symptoms are at first slight, or chiefly de- pendent on the pressure of the parts within the pelvis. The patient is costive, and subject to piles, has a degree of stran- gury, which in a few instances, may end in a complete re- tention of urine; and sometimes one of the feet swells. By examining per vaginam, a tumour may often be felt betwixt the vagina and rectum, and the os uteri is thrown forward near the pubis; so that, without some attention, the disease may be taken for retroversion of the womb.* In some time after this, the tumour, in general, rises out of the pelvis," and these symptoms go off. A moveable mass can be felt in the hypogastric, or one of the iliac regions. This gradually enlarges, and can be ascertained to have an obscure fluctua- tion. The tumour is moveable, until it acquire a size so great, as to fill and render tense the abdominal cavity. It then resembles ascites, with which it in general comes to be ultimately combined76. Little inconvenience is produced, except from the weight of the tumour, and the patient may enjoy tolerable health for years. But it is not always so, for the tumour sometimes presses on the fundus vesicae, produc- ing incontinence of urine, or on the kidney, making part of it to be absorbed; and it often irritates the bowels, causing uneasy sensations, and sometimes hysterical affections.f It * Mr. Home's case related by Dr. Denman, Vol. I. p. 130, had very much the appearance of retroversion. f Case by Sh- Hans Sloane, in Phil. Trans. No. 252.—Dr. Pidtcny's patient, 110 augments in size, and carries up the uterus with it ;* so that the vagina is elongated: and this is especially the case, if both ovaria be enlarged,7' The urine is not in the com- mencement much diminished in quantity, unless this disease be conjoined with ascites; and the thirst at first, is not greatly increased." But when the tumour has acquired a great size, tho urine is generally much diminished or ob- structed.* If, however, the bulk be lessened artificially, it is often, for a time, increased in quantity, and the health im- proved. This is well illustrated by the case of Madame de Rosney,f who in the space of four years, was tapped twenty- eight times: for several days after each puncture, she made water freely, and in sufficient quantity; the appetite was good, and all the functions well performed : but in proportion as the tumour increased, the urine, in spite of diuretics, diminished, and at last came only in drops. The woman ge- nerally continues to be regular for a considerable time, and may even become pregnant. In the course of the disease, the patient may have attacks of pain in the belly, with fever, indicating inflammation of part of the tumour, which may terminate in suppuration, and produce hectic fever; but in many cases, these symptoms are absent, and little distress is felt, until the tumour acquire a size so great as to obstruct respiration, and cause a painful sense of distention. By this time, the constitution becomes broken and dropsical effusions are produced. Then the ab- dominal coverings are often so tender, that they cannot bear pressure; and the emaciated patient, worn out with restless nights, feverishness, want of appetite, pain, and dyspnoea, expires. The symptoms of this disease all arising, either from pres- sure or irritatftm, must vary according to the nature of the whose ovarium weighed fifty-six pounds, had excruciating pain in the lefi» side, spasms, and hysterical fits. Mem. of Medical Society, Vol. II. p. 265. * This point is well considered by M. Voisin, in the Recueil Period. Tome XVII. p. 371, et seq.—The bladder may also be displaced, as in the case of Mademoiselle Argant, related by Portal. Cours d'Anat. Tome V. p. 549. t Portal. Cours d'Anat Tome V. p. 549. Ill parts most acted on, and the peculiar sympathies which exist in the individual. When we consider that, in many in- stances, the whole constitution, as well as different organs, may bear without injury, a great, hut very gradual irritation, it is not surprising that this disease, which, for a long time, operates only mechanically, .should often exist for years with- out affecting the health materially, whilst'in more irritable habits, or under a different modification of pressure, much distress, too often referred to hysteria, may be produced. This disease has sometimes appeared to be occasioned by injury done to the uterus in parturition, as, for instance, by hasty extraction of the placenta; or by blows, falls, violent passions, frights, or the application of cold; but very often, no evident exciting cause can be assigned. In the first stage of this complaint, we must attend to the effects produced by pressure. The bladder is to be emptied by the catheter, when this is necessary; and stools are to be procured. It may be considered, how far, at this period, it is proper to tap the tumour from the vagina, and by injections or other means, endeavour to promote a radical cure. When the woman is pregnant, and the tumour opposes delivery, there can be no doubt of the propriety of making a puncture,78 which is preferable to the use of the crotchet(a) But this has only been resorted to, in order to obviate particular in- conveniences, and affords no rule of conduct in other cases, where no such urgent reason exists. I am inclined to dissuade strongly from any operation at this period, because in a short time the tumour rises out of the pelvis; and then the patient may remain tolerably easy for many years. Besides the ova- rium in this disease contains, in general, numerous cysts; and as these, in the first stage, are small, we can only hope to empty the largest. Perhaps we may not open even that; and although it could be opened and healed, still there are others coming forward, which will soon require the same treat- (a) Where the tumour in the vagina occupies a large space, Dr. Merriman thinks it a warrantable practice to remove it by excision if it consisted of a soBd substance, and certainly to puncture it if it contained a fluid. Vide Me- dico>Chirurgical Transactions, Vol. HI. p. 47. 112 ment. Puncturing, then, can only retard the growth of the tumour, and keep it longer in the pelvis, where its presence is dangerous. When the tumour has risen out of the pelvis, we must, in our treatment, be much regulated by the symptoms. The bowels should be kept open, but not loose, by rhubarb and magnesia, aloetic pills, cream of tartar, or Cheltenham salt. Dyspeptic symptoms may sometimes be reliev ed by prepara- tions of steel, combined with supercarbonatc of soda, or other appropriate medicines, though their complete removal cannot be expected as long as the exciting cause remains. General uneasiness or restlessness, occasionally produced by abdomi- nal irritation, may be lessened by the warm bath, saline ju- lap, and laxatives; whilst spasmodic affections are to be re- lieved by fcetids; and if these fail, by opiates. If, at any time, much pain be felt, we may apply leeches, and use fomen- tations, or put a blister over the part. Upon the supposition of this disease being a dropsy, diuretics have been prescribed, but not with much success,79 and often with detriment. Some have supposed, that diuretics do no good whilst the disease is on the increase; but that, when it arrives at its acme, they are of service. But this disease is never at a stand; it goes on increasing, till the patient is destroyed. When they pro- duce any effect, it is chiefly that of removing dropsical affec- tions combined with this disease; and in this respect, they are most powerful immediately after paracentesis. With regard to the power of diminishing the size of the ovarium, my opinion is, that they have no more influence on it, than they have over a mellicerous tumour on the shoulder. In one case, fomentations and poultices appear to have discussed a tumefied ovarium.* Having palliated symptoms until the distension becomes troublesome, we must then tap the tumour, which gives very great relief; and, by being repeated according to circumstan- ces, may contribute to prolong life for a length of time.80 As the uterus may be carried up by the tumour, it is proper to • Vide Dr. Monro's fourth case, in Med. Essays, Vol. V. 113 ascertain, whether it be the right ovarium or the left which is enlarged; and we should always tap the right ovarium.on the right side, and vice versa: by a contrary practice, the uterus has been wounded.* When the disease is combined with ascites, it is sometimes necessary to introduce the trocar twice, and the difference between the two fluids drawn off is often very great. We must neither delay tapping so long as to injure by great irritation and distention; nor have recourse to it too early, or too frequently, for the vessels of the cavity excrete much faster and more copiously after each operation, and it is to be remembered, that this is a cause of increasing weakness, not only from the expenditure of gelatinous fluid, but also from the increased action performed by the vessels, which must exhaust as much as any other species of exer- tion. Finally, it has been proposed, to procure a radical cure, by laying open the tumour, evacuating the matter, and prevent- ing the wound from healing, by which a fistulous sore is pro- duced ; or by introducing a tent, or throwing in a stimulating injection. Some of these methods have, it is true, been suc- cessful,81 but occasionally they have been fatal ;82 and in no case, which I have seen, have they been attended with benefit. There are two powerful objections to all these practices, be- sides the risk of exciting fatal inflammation: the first is, that ftie cyst is often irregular on its interior surface, and therefore cannot be expected to adhere: the second is, that as the ova- rium, when dropsical, seldom consists of one single cavity, so, although one cyst be destroyed, others will enlarge, and renew the swelling; and, indeed, the swelling is seldom or never completely removed, nor the tumour emptied, by one operation. Hence even as a palliative, the trocar must some- times be introduced into two or more places. It has happened, that a cyst has adhered to the intestine,8,3 and burst into it, the patient discharging glary or feetid mat- ter by stool.84 Such instances as 1 have known, have only * In a case of this kind related by M. Voisin, the uterus was wounded, and the patient felt great pain, and fainted. She died on the third day after the operation. Recueil Period. Tome VII. p. 37*, &c. VOL. T. Q Ill been palliated, but not cured, by this circumstance. Some- times the fluid has been evacuated per vaginam,85 or the ova- rium has opened into the general cavity of the abdomen, and the fluid been effused there. There is another disease, or a variety of the former dis- ease, in which bones, hair, and teeth, are found in the ova- rium.86 The sac, in which these are contained, is sometimes large, and generally is filled with watery or gelatinous fluid. The bony substance, and teeth, usually adhere to the inner surface of the cyst. This disease produces no inconvenience, except from pressure. It has been deemed by some, to he merely an ovarian conception; hut it may undoubtedly take place without impregnation, nay similar tumours have been found in the male sex.87 It is to be treated as the former disease. § 42. OTHER DISEASES OF THE OVARIUM. The ovaria are sometimes affected with scrophula, and the tumour may prove fatal by producing retention of urine. When it rises out of the pelvis, it is often productive of hypochondriasis, and very much resembles the ovarian dis- ease, formerly mentioned, but is firmer, seldom gives a sen- sation of fluctuation, and sometimes is very painful when pressed. It rarely terminates in suppuration ; but when it does, the fluid, as Portal observes, is blanchatre, filamenteux. grumeleux, mal digere. The substance of the ovarium is soft, and similar to that of other scrophulous glands. Occasion- ally it contains a cheesy substance, which is found, at the same time, in the mesenteric and other glands. Burnt sponge, cicuta, mercury, electricity, laxatives, &c. have been employed, hut seldom with benefit. The most we can do, is to palliate symptoms, such as retention of urine, cos- tiveness, dyspepsia, or pain. The ovarium may also be enlarged, and become hard and stony,88 or converted into a fatty substance.89 Sometimes it is affected with the spongoid disease, and is changed into a substance like brain, with cysts containing bloody serum. 115 The tumour in this disease, feels tense and clastic. It may burst through the abdominal parietes, and throw out large fungous excrescences. Frequently we find, on cutting an enlarged ovarium, that part of it resembles the spongoid structure, havjrjg bloody fungous cysts; part is like firm jelly, and pat&like cartilage, or dense fat.. Often the uterus participates in the disease. I have seen a mass of this kind weigh thirteen pounds. I have never found the ovarium cancerous. § 43. DEFICreNCY. The ovaria may be wanting on one or both sides,(6) or may be unusually small. In such cases, it sometimes hap- pens, that the growth of the external parts stops early, and the marks of puberty are not exhibited. The ovarium may form part of a herniary tumour. § 44. DISEASES OF THE TUBES AND LIGAMENTS. The tubes may be wanting, or impervious, and are sub- ject to many of the diseases of the ovaria. The round ligaments may partake of the diseases of the uterus, or may have similar diseases, originally appearing in them. WThen they are affected, pain is felt at the ring of the oblique muscle, artd sometimes a swelling can be per- ceived there. (b) See a case of deficiency of the ovaria, by Charles Pears, F. L. S. in the Phil. Trans, for 1805. This woman died at the age of twenty-nine. She had never menstruated. She ceased to grow at the age often years 116 CHAP. XI. Of Menstruation. The periodical discharge of sanguineous fluid which takes place every month from the uterus, is termed the menses; and whilst the discharge continues, the woman is said to be out of order, or unwell. In some instances, the discharge takes place at puberty, without any previous or attendant indisposition; but in most cases, it is preceded by uneasy feelings, very often by affec- tions of the stomach and bowels, pain about the hack and pel- vis, and various hysterical symptoms. These affections, which are more or less urgent in different individuals, gra- dually abate; but at the end of a month, return with more severity, attended with colic pains, quick pulse, sometimes hot skin, and a desire to vomit. There now takes place from the vagina, a discharge of a serous fluid, slightly red, but it does not in general become perfectly sanguineous for several periods. When the discharge flows, the symptoms abate; but frequently a considerable degree of weakness remains, and a dark circle surrounds the eye. In a short time the girl menstruates, often without any other inconvenience than a slight pain in the back, though sometimes, during the whole of her life, she suffers from many of the former symp- toms every time she is unwell; and all women, at the men- strual period, are more subject than at other times to spas- modic and hysterical complaints. When a girl begins to menstruate, certain changes take place, denoting the age of puberty. The uterus becomes more expanded, and receives its adult form; the vagina en- larges; the mons veneris swells up, and is covered with hair; the pelvis is enlarged; the glandular substance of the breasts is unfolded, and the cellular part increased; at the same time the mental powers become stronger, and new passions begin to operate on the female heart. The age at which menstruation begins, varies in indivi- 117 duals, and also in different climates. It is a general law, that the warmer the climate, the earlier does the discharge take place, and the sooner does it cease. In Asia, for instance, the menses begin about nine years of age; whilst in the North, a woman does not arrive at puberty until she is eigh- teen or twenty years old; nay, if we may credit authors, in very cold countries, women only menstruate in the summer seasons.* In the temperate parts of Europe, the most com- mon age at which the menses appear, is thirteen or fourteen^ years.f The quantity of the discharge varies, also, according to the climate and constitution of the woman. In this country from six to eight ounces are lost at each menstrual period; but this does not flow suddenly; it comes away slowly for the space of three or four days. Some women discharge less than this, and are unwell for a shorter space of time: others, especially those who live luxuriously, and are confined in warm apartments, menstruate more copiously, and continue to do so for a week. In this country, menstruation ceases about the forty-fourth year, lasting for a period of about thirty years. In the East, the menses begin soon, flow copiously, and end early; the women in Asia, for example, being old, whilst the Europeans are still in their prime. In the north, the menses begin late, flow sparingly, and continue long. The menses are obstructed during pregnancy,:): and the giving of suck; but if lactation be very long continued, the menses return, and the milk disappears or becomes bad. * Linnaeus and others have said that the women of Lapland do not men- struate more than once or twice in the year. C. f Menstruation commences about the same age in the United States, and continues to the fortieth or forty-fifth year. C. % This is a point still debated. The weight of authority is, however, de- cidedly against menstruation continuing during pregnancy. By Baudelocque, Denman, and almost all the modern writers,it is denied. Those who main- tain the contrary opinion, have very probably mistaken a hemorrhage from the vagina, which sometimes recurs with considerable periodical regularity, for the menstrual flux. Several cases of this kind have come under my own observation, where I had an opportunity of examining the discharge accu- rately. In every instance, I found it pure coagnlable blood. 118 The discharge appears to be yielded by the uterine arte* lies, but is not an extravasation or hemorrhage, for when collected, it does not separate into the same parts with blood, neither does it coagulate.(c) In many instances, a great quan- tity has been retained for some months in the uterus and vagina, but it has never been found clotted when it was eva- cuated. Menstruation has-been attributed to the influence of the moon, to the operation of a ferment in the blood, or in the uterus, to the agency of a general or local plethora, or to the By adverting to the state of the pregnant uterus, this is exactly what we should be led to expect. Contemporary with conception, we know that the uterine cavity is lined with the membrana, decidua, and that soon after- wards the os tincv, what may readily be seen by examining the uterus, that the fibres are not very re- gular and distinct in their course, but exhibit confusion, rather than any well marked figure. The increased sized of the uterus is by no means chiefly ow- ing to the addition of muscular fibres. These become indeed larger, and better developed, but do not contribute so much to the increase, as the enlargement of the blood vessels, and perhaps the deposition of cellular substance. This gives the uterus a very spongy texture, and makes it so ductile, that a small aperture may be greatly dilated, without tearing.(rc) From examination, it appears, that although the whole uterus does not grow thinner in proportion to its increase, it yet does, at the full time, become thinner near the mouth ; whilst the fundus continues the same, or perhaps grows a little thicker, at least where the placenta is attached. | 4. LIGAMENTS. No one, who understands the anatomy of the ligaments of the unimpregnated uterus, will be surprised to find a great change produced in their situation and direction, by preg- nancy. The broad ligament, which is only an extension of the peritoneum from the sides of the uterus, is, in the ninth month, by the increase of the viscus, spread completely over its surface; and consequently, were we to search for this liga- ment, we would be disappointed. Its duplicatures are all separated, and laid smoothly over the uterus. It will there- fore be evident, that we can no longer find the ovaria and fallopian tubes floating loose in the pelvis, nor the round (?i) See a paper already referred to on the Muscularity of the Uterus, by Charles Bell, Esq. F. R. S. Eilin. pubhshed in the 5th vol. of the Eclectic Repertory, p. 27. Off ligaments running out at an angle from the fundus uteri to the groin. All these are contained within duplicatures of the peritoneum, or ligamentum latum; and therefore, when this is spread over the uterus, it follows, that the ovaria, tubes, and round ligaments, cannot now run out loosely from the uterus, hut must be laid flat upon its surface, and bound down by the stretched peritoneum. This description applies only to the state of the uterus in the full time. Earlier, we may readily observe the broad ligament flying out, and al- lowing the ovaria free play. The loose extremity of the tube becomes more expanded, and very vascular, and forms a kind of cavity called the antrum. On the ovarium we observe a corpus luteum. This is & substance something like a gland, divisable into cortical and medullary matter, placed immediately under the membrane of the ovarium, and adhering to the ovarium by cellular sub- stance. By separating this, it can be turned out. It is of a yellowish colour, and is largest soon after conception. There is a corpus luteum for every foetus. § 5. VESSELS. The origin, and distribution of the blood vessels of the uterus have been already noticed; I have only to add, that in pregnancy, they become prodigiously enlarged. Even before the ovum enters the uterus, we find the uterine artery as large as the barrel of a goose quill, and sending large branches round the cervix uteri, and up the sides of the womb. As pregnancy advances, the trunks, but especially the branches, become still larger, particularly near the im- plantation of the placenta. The veins are enlarged in the same proportion with the arteries. They are destitute of valves, and receive the name of sinuses. The lymphatics are very large and very numerous. The lwrves have already been described. 14H § 6. OF THE F02TUS. Although many opportunities have occurred to anatomists, of examining not only abortions, but also the uterus itself, at an early period of gestation; yet it has not been exactly determined at what precise time the ovum enters the womb, or when the foetus first becomes visible. This may depend, partly on want of information respecting the exact number of days which have intervened betwixt impregnation and our examination; and partly, perhaps, upon irregularities of the process in the human female, induced by various causes. We know that considerable changes take place in the cavity of the uterus, before the ovum descends, and these generally are not accomplished in less than twenty or thirty days. In a very accurate dissection performed by the late Mr. Hun- ter, and related by Mr. Ogle,* no ovum could be found either in the uterus or the tubes, although there is reason to sup- pose that nearly a month had elapsed from the time of im- pregnation. I have examined very carefully three uteri about the same period, and have not been able to discover either ovum or foetus. If we admit analogical evidence on this subject, we shall be more confirmed in a belief that the ovum does not, in the human female, enter the uterus, until at least three weeks after conception.! In the rabbit, whose period of gestation is only thirty days, the ovum is not to be found in the uterus earlier than the fourth day, according to Mr. Cruikshanks,! or the sixth, according to Dr. Haigh- ton ; and the foetus is not visible till the eighth day, when it may be seen by dropping vinegar on the ovum.§ Haller found, that in the sheep, whose term of gestation is five months, the ovum does not enter the uterus till the seven- teenth day,|| and the foetus is not visible till the nineteenth. * Transactions of a Society, &c. Vol. II. Art vi. ■J- Dr. Comb possessed a preparation, where there was an appearance of a very minute fcetus. From pecuhar circumstances, two and twenty days were supposed to have elapsed from the time of conception. Vide Dr. Hunter's Anatom. Descrip. p. 87. * Phil. Trans. Vol. LXXXVII. § Phil. Trans. Vol. LXXXVII. p. 204. D Elementa, Tom. A in. p. 59.—Opera Minora, Tome II. p. 434. 149 The ovum, at first, contains no visible embryo ; nothing but vesicular involucra appear. This point is fully esta- blished by examining the inferior animals, and is especially confirmed by the incubation of the eggs of fowls. I have ex- amined carefully a most perfect ovum in the ninth week after menstruation, consequently not less than the fifth after con- ception. In it no embryo could be detected. The chorion was as large as a small chesnut, covered with shaggy vessels, and filled with transparent jelly like the vitreous humour of the eye. Within, and adhering to one side, was the amnion, not much larger than a coriander seed.* It contained nothing but transparent fluid. When the human foetus is first distinctly visible through the membrane, it is not above a line in length, and of an oblong figure. In the sixth week, it is seen slightly curved, resembling, as it floats in the water, a split pea. In the seventh week, it is equal in size to a small bee; and, by the conclusion of the second month, it is bent and as long as a kidney bean. The embryo, at first, appears like two oval bodies of un- equal size, united together by a neck. The one of these is the head, the other the trunk. The head is a membranous bag, which is large in proportion to the body; but after the first month of its growth, the relative size decreases: on opening it, nothing but a soft pulp is found within. In a little time, the face appears, the most prominent features of which are the eyes; these are proportionally larger in the embryo than in the advanced foetus, and are placed low down. The face itself is small, compared to the cranium. The nose does not appear until the end of the second month ; but some- what sooner, we may obsci've two apertures in the situation of the nostrils. The mouth, at first, is a round hole, but by degrees lips appear; and after the third month, they are closed, but do not cohere. The external ear is not formed at once, but in parts, and is not completed before the fifth month; even then, it differs in its shape from the car after birth. It is at first like a gently depressed circle. The extremities early appear like the buds of a plant. The 150 arms are directed obliquely forward, toward the face, and are larger than the inferior extremities. The genitals, for a time, are scarcely to be observed; but in a third month, they are large in proportion to the body. The foetus does not grow in a uniform ratio, but, as has been observed, by the learned anatomist, Dr. Soemmering,(o) the increment is quicker in the third than in the second month. In the beginning of the fourth it becomes slower, and continues so until the middle of that month, when it is again accelerated. In the sixth month, it is once more re- tarded, and the progression remains slow during the rest of gestation. The proportion between the weight of the foetus and its involucra, is reversed at the beginning and the end of gesta- tion. When the embryo does not weigh more than a scruple, the membranes are as large as a small egg. Even when the fcetus is not larger than a fly, the membranes resemble, in shape and size, a large chesnut. On the other hand, at the full time, when the foetus weighs seven pounds, the placenta and membranes do not weigh a pound and a half, and the pro- portion of liquor amnii is greatly lessened. In the twelfth week, the foetus weighs nearly two ounces, and measures, when stretched out, about three inches. The membranes are larger than a goose's egg, and weigh, if we include the liquor amnii, several ounces. In the fourth month, the foetus is about five inches long. In the fifth month, it measures six or seven inches. In the sixth month, the foetus is perfect and well formed, measures eight or nine inches, and weighs about one pound troy; whilst the placenta and membranes weigh about half a pound, exclusive of the liquor amnii. The foetus (o) The student is particularly requested, where that most valuable work is within his reach, to compare this description of the foetus in its different stages of progressive developement and growth, with the most accurate and elegant plates of Soemmering, entitled, Icones Embryonum Humanorum. Dr. Hunter's plates of the gravid uterus, are also highly worthy of inspection. These invaluable works may be almost said to supply the place of anatomical preparations; so closely and minutely has nature been copied by the faithful pencil and graver of the artist. 151 is now so vigorous in its action, that there have been in- stances, though most rare, of its continuing to live, if born at so premature a period. In the seventh month, it has gained about three inches in length, and is now more able to live in- dependent of the uterus; though even at this time, the chance of its surviving six hours from birth is much against it. In the eighth month, it measures about fifteen inches, and weigh four, or sometimes five pounds, whilst the involucra weighs scarcely one. These calculations vary according to the sex of the child, and also the conformation of the parents. Male children generally weigh more than females. Dr. RoedeBer* concludes, from his examinations, that the average length of a male, at the full time, is tvv enty inches and a third, whilst that of a female is nineteen inches and seventeen eighteenths. Dr. Joseph Clarke has given a table of the comparative weight of male and female children at the full time, from which it appears, that although the greatest proportion of both sexes weigh seven pounds, yet there are more females than males found below, and more males than females above that stand- ard. Thus, whilst out of sixty males, and sixty females, thirty-two of the former, and twenty-five of the latter, weighed seven pounds, there were fourteen females, but only six males, who weighed six pounds. On the other hand, there were sixteen males, but only eight females, who weighed eight pounds. Taking the average weight of both sexes, it will be found, that twelve males are as heavy as thirteen fe- males. The placenta of a male, weighs, at an average, one pound two ounces and a half, whilst that of a female weighs half an ounce less. Female children, who, at the full time, Weigh under five pounds, rarely live; and few males, who even weigh five pounds, thrive. They are generally feeble in their actions, and die in a short time. When there are two children in utero, the weight of each individual is generally less than that of the foetus who has no companion; but their united weight is greater. When a woman has twins, it either usually happens, that both chil- * Comment. Gottin. 1753. 152 drcn are small, or one is of a moderate size, and the other is diminutive; though I have known instances, where both the children were rather above, than under the usual stand- ard. The average weight of twelve twins, examined by Dr. Clarke, was eleven pounds the pair, or five and a half each. Twins require more pabulum from the mother, and a greater degree of action in the uterus; for two placenta; must have their functions supported. The uterus is also generally more distended, and produces greater irritation; it has more blood circulating in it; and the weight of its contents, to that with a single child, has been stated as twenty to fifteen. Twin gestation often produces a greater effect on the system, making the woman more disposed to disease, and less able to bear it; hence the chance of recovery has been supposed to be four times less in them, than in those who have single children. The children, being generally feebler than when only one is contained in the uterus, are more disposed to disease; and, as the mother is less able to suckle children after a twin labour, many perish, who might have been pre- served, by providing a good and careful nurse, soon after birth, for the weakest child. When the number of children increases above two, the ag- gregate weight does not increase. Thus Dr. Hull of Man- chester met with a delivery of five children, who did not weigh two pounds and a quarter; they measured from eight to nine inches in length, and two of them were born alive. Calculations have been made of the proportion of single births, those where there were a plurality of children. In the Dublin hospital, one woman in fifty-eight had twins. In the British lying-in hospital, one in ninety-one. In the West- minster hospital, one in eighty. In my own practice, about one in ninety-five.(jf) In the Dublin hospital, triplets have (p) In the lying-in hospital, called l'Hospice de la Maternite at Paris, about one in eighty-nine had twins, as appears from Baudelocque's Tableau des Accouchemens. In the lying-in ward of the Philadelphia alms-house, as appears from a re- gular record kept for 19 years, enchng 1815, one woman in about 52 had twins. The proportion of males to females, born within the above period, was about 10 males to 8 females. 153 not occurred above once in five thousand and fifty- times.(«7) More than three are not met with, once in twenty-thousand times. The proportion of male children, born in single births, is greater than of females. In an extensive parish in this place, the number of males, born in a given time, was to that of females, as 3716 to 3177. In the Westminster hospital, it was as 972 to 951; but in the same hospital, it is worthy of remark, that the number of male twins was only 16, whilst that of females was 30.(r) § 7. ITS PECULIARITffiS. The foetus has many peculiarities which distinguish it from the adult, and which are lost after birth, or gradually removed during gestation. In particular, the liver is of great size, by which the abdomen is rendered more prominent than the thorax. It appears very early, and increases rapidly till the fourth month, after which its growth is slower. In the child, after birth, the greatest quantity of blood in the liver is venous, and from this the bile seems to be secreted. But in the foetus, the blood is more nearly approaching in its nature to arterial; and no bile, but a fluid different in its properties, is secreted. The gall bladder is filled with a green fluid, which, before birth, becomes darker, with a tinge of blue, but is said not to have a bitter taste. The umbilical vein, which contains blood, changed in the pla- centa, enters the liver, and sends large branches to the left side; the vena porta enters the liver, and ramifies on the right side; whilst a branch, or canal of communication, is sent from the umbilical vein to the vena portae. By this con- trivance, the left side is supplied altogether with pure blood A different average, particularly as it regards the proportion of twin cases, was stated in the former edition of this work, but that was taken from the result of five years only, in which twin cases had very rarely occurred. (g) In l'Hospice de la Maternite at Paris, triplets occurred but twice in 12,605 women. (r) Of 12,751 infants born in the lying-in hospital at Paris, above alluded to, 6,524 were males, and 6,227 females. VOL. I. X 154 from the placenta, and the right side is supplied with a mix- ture of pure and impure blood, which does not form perfect bile. After birth, as the circulation from the placenta is stopped, the branches of the umbilical vein, which supplied the left side, would be empty, did not the canal, which for- merly served to carry a portion of blood from this vein to the vena portse, now permit this latter vessel to fill the branches in the left side, which henceforth form a part of the vena porta. The whole liver is thus supplied with blood en- tirely veinous. Bile is formed, and sometimes in very con- siderable quantity. The blood of the foetus differs from that of the adult. It forms a less solid coagulum, for, in place of fibrous matter, it yields a soft tissue, almost gelatinous. It is not rendered florid by exposure to air,* and it contains no phosphoric salts. But soon after the foetus has respired, the colouring matter, exposed to oxygen, acquires the vermilion tint; and salts are formed, particularly the phosphate of lime. The stomach is smaller in the foetus, than in the child after birth. The intestines, which at first, are seen like threads arising from the stomach, are redder, and said to be longer in proportion to the body in the foetus, than in the child. They are at first uncovered, but, after some time, the abdo- minal muscles and integuments form a complete inclosure. They contain a soft substance like ointment, of a dark green colour, called meconium. The testicles of the male, and the ovaria of the female, lie on the psose muscles, but, before birth, the testicles pass into the scrotum. The kidneys are large and lobulated, and the ureters thick. The glandulse renales are large, and contain a reddish fluid. The bladder is more conical and lengthened than in the adult. The lungs are dense and firm, and a large gland, called thymus, is contained in the thorax. The heart is very different from its adult state. In the chick, we find that there is in the situation of the heart, a single cavity * Bichat made experiments to ascertain this upon Guinea pigs, and always found the foetal blood black. Anatomie Generale, Tome II. p. 343. 155 which afterwards corresponds to the left ventricle. At the forty-sixth hour, the ventricle and bulb of the aorta are visi- ble. Then an auricle is formed by the vena cava: this auricle does not adhere directly to the ventricle, until the sixth day, but is connected with it till that time by a short duct, called canalis auricularis. In about ninety-six hours the auricle begins to exhibit marks of a division into two cavities, or a right and left side; and some time afterwards, the right ven- tricle and lungs are evolved. The structure of the heart, however, is still different from that which obtains after birth; for though the auricles are divided into two cavities, yet these are seen, in the human foetus, to communicate freely by a vacancy in the septum ; and even after this is supplied, it is only with a valve, which allows the blood to pass from the right to the left side. This is the foramen ovale, which is shut up after birth. Another peculiarity of the foetal heart is, that the pulmonary artery, although it divide into two branches for the lungs, yet sends a third, and still larger branch, directly into the aorta, just at its curvature, and this is the ductus arteriosus. The blood is received in a purified state from the placenta, by the umbilical vein, which, after giving off branches in the liver, sends forward the continua- tion of the trunk, to terminate in the vena cava, or largest of the hepatic veins, and this continuation is named ductus venosus. The mixed blood which is thus found in the vena cava, is carried to the right auricle, and thence to the cor- responding ventricle. By the pulmonary artery it ought to be conveyed to the lungs, but this would be useless in the foetus, and therefore the greatest part of it passes on by the ductus arteriosus to the aorta. But it follows from this, that as little blood is carried to the lungs, so little can be brought from them by the pulmonary veins to the left auricle. Now, to obviate this, and fill that auricle at the same time with the right, the foramen ovale is formed ; and thus, as the blood can pass freely from the right to the left, the two auricles are to be considered as one cavity, being filled and emptied at the same time. The aorta is distributed to the different parts of the body; 156 but this singularity prevails, that the hypogastric vessels run up all the way to the navel, and pass out to form the umbili- cal arteries. After birth, these arteries are obliterated in their course to the navel; and the foramen ovale, and ductus arteriosus become impervious. The head of the foetus is, at first, membranous, and the brain a pulp, soluble in aqua kali puri. By degrees, distinct cartilaginous plates are formed over the brain, which are gradually converted into bones. These, at birth, are only united by intermediate membranes. The pupil of the eye, till the seventh month, is shut up by a membrane; and the eyelids, for some months, adhere together. The skin is covered with a white substance, which, though unctuous to the feel, does not melt, but dries and crackles by heat. It is miscible with spirits, or with water, through the medium of soap or of oil. The male foetus differs from the female, in having the head larger, but less rounded, and flatter at the back part. The thorax is longer, and more prominent, and formed of stronger ribs than in the female. In her, it is wider from the upper part to the fourth rib, and narrower below; the belly, also, in the female, is more prominent, and the symphysis pubis projects more. The upper extremities are shorter than those in the male; the thighs are thicker at the top, and more tapering to the knees. Dr. Soemmering says, that the spi- nous processes of the lower dorsal, and upper lumbar ver- tebra, make in the male an eminence like a yoke, in the fe- male a sinuosity. I may remark, that as the clitoris is large in the young foetus, females sometimes pass in abortions for males. When in utero, the foetus assumes that posture which occu- pies least room. The trunk is bent a little forward, the chin is pushed down on the breast, the knees are drawn up close to the belly, and the legs are laid along the back part of the thighs, with the feet crossing each other. The arms are thrown into the vacant space betwixt the head and knees. This is the general position, and the child thus forms an oval 157 figure, of which the head makes one end, and the breech the other. One side of it is formed by the spiuc and back part of the head and neck, and the other by the face and contract- ed extremities. The long axis of this ellipse measures, at the full time, about ten inches, and the short one, five or six. In the eighth month, the long axis measures about eight inches. In the sixth, betwixt four and five. In the fourth month, it measures nearly three inches and a half: and in the third, about an inch less. In the early months, however, there is no regular oval formed, and these measurements are taken from the head to the breech, which afterwards form the ends of the distinct ellipse. The extremities are at first small and * slender, and bend loosely toward the trunk. § 8. UMBHJCAL CORD. The umbilical cord is an essential part of the ovum, con- necting the foetus to its involucra. It is found in oviparous and viviparous animals, and also in plants; but in these dif- ferent classes, it appears with many modifications. In the human subject, it consists of three vessels; of which two are arteries, and one is a vein. These are imbedded in gluten, and covered with a double membranous coat. The two arte- ries are continuations of the arteria hypogastrica of the child, and passing out at the navel, run in distinct and unconnected trunks, until they reach the placenta, where they ramify and dip down into its substance. When they reach the placenta, the one artery, in some cases, sends across a branch to com- municate with the other. The vein commences in the sub- stance of the placenta, forms numerous rays on its surface, corresponding to the branches of the arteries; and near the spot where the arteries begin to give off branches, these rays unite into a single trunk, the area of which is rather more than that of the two arteries. None of these vessels are fur- nished with valves. The umbilical vessels run in a spiral direction, within the covering of the cord, and the twist is generally from right to left. Besides this twisting, we also find, that the ve-sels, 15S especially the arteries, form very frequently coils, loosely lodged in the gluten. The cord does not consist entirely of vessels, but partly of a tenacious transparent gluten, which is contained in a cel- lular structure ; and these numerous cells, together with the vessels, are covered with a sheath, formed by the reflection of both chorion and amnion from the placenta, and of neces- sity, the amnion forms the outer coat of the cord. The cho- rion adheres firmly to the cord every where, but the amnion does not adhere to the chorion; it is not even in contact with it at the placental extremity, but forms there a slight expan- sion, which, from its shape, has been called by Albinus, the processus infundibuliformis. The proportion of gluten is larger in the early than in the advanced stage of gestation; and the vessels, at first, run through it in straight lines. In some instances, the cells dis- tend or augment in number, so as to form tumours on the cord, which hang from it like a dog's ear. There is a small sac, or bladder, found on the placenta, at or near the extremity of the cord, in the early part of gesta- tion It is most distinct betwixt the third and fourth month of pregnancy, and is placed exterior to the amnion. It is filled, though not quite distended, with a whitish fluid, on which account, it is called the vesicula alba.* From this, a very fine vessel proceeds along the cord, adhering firmly to the amnion ; but, without a glass, it cannot be traced all the way to the navel. It has been supposed to be subservient to the nourishment of the foetus in its early stage. A small ar- tery and vein pass along the cord from the navel, to the ve- sicle which is between the chorion and amnion. These are the omphalo-mesenteric vessels. Besides the blood vessels, there is in brutes another vessel, which is a continuation of the fundus vesica. It passes out at the navel, and, running along the cord, terminates in a bag, which is placed betwixt the chorion and amnion. . The bag, is called the allantoic, and the duct the uradius. * Vide Albinus, Annot. Acad. lib. I. cap. xix. p. 74. et tab. 1. fig. 12. 159 In the human subject, in place of the urachus, we find only a small white impervious cord. There is of course no allan- tois. When the ovum is first visible in the uterus, there is no cord, the embryo adhering directly to the involucra, but it soon recedes ; apd about the sixth week, a cord of communi- cation is perceptible. The cord at the full time varies in length, from six in- ches* to four feet ;f but its usual length is two feet. When it is too long, it is often twisted round the neck or body of the child, or occasionally has knots formed on it4 most fre- quently, perhaps, by the cliild passing through a coil of it during labour.^ The vessels of the cord sometimes become varicose, and form very considerable tumours. These, occasionally, so far impede the circulation, as to interfere with the growth of the child, or even to destroy it altogether. Sometimes the ves- sels burst, and blood is poured into the uterus, which pro- duces a feeling of distension, and excites pain. There can however, be no certainty of this accident having taken place until the membranes burst, when clots of blood are discharg- ed. If the foetal and maternal vessels should communicate, the mother is weakened, and may even faint; and, in every instance, the child suffers, but does not always die.|| Deli- very must be resorted to, either on account of the effects produced on the mother, or to prevent the destruction of the child. The cord may by a fall, or violent concussion of the body, be torn at a very early period of gestation. In this case, the child dies, but is not always immediately expelled. It may be retained for several weeks; afterwards the ovum is thrown * Hildanus, cent. II. obs. 50. f Mauriceau has seen it a Paris ell and a third, obs. 401.—Hebenstreit 40 inches—Haller Disp. Anat. Tom. V. p. 675.—Wrisberg 48 inches.—Vide Com. Gotting. Tom. IV. p. 60. * Vide Mauriceau, obs. 133 and 156. 4 Dr. Hunter thinks he has twice seen these formed previous to birth. H Vide Baudelocque l'Art, note to section 1084. 160 off, like a Confused mass, inclosing a foetus, corresponding in size to the period when the accident happened.* The cord may be filled with hydatids. The cord has been found unusually small and delicate, or, on the contrary, very thick. In the latter case, it is always proper to apply two ligatures, instead of one, on the portion which remains attached to the child.f It has happened, that, by the shrinking of the cord under the ligature, the child has died from hemorrhage.^: Two cords have been met with, connected with one pla- centa, or with two placenta belonging to one child. In other instances, the vessels are supernumerary or deficient. Stories have been told of the cord being altogether wanting, but these are incompatible with the foetal economy. § 9. PLACENTA. A placenta, or something equivalent to it, is to be found connected with the young of every living creature. We find it requisite that a pabulum should be supplied to every animal, and that certain changes should be performed on the blood, qualifying it for supporting life. In oviparous animals, two different parts of the ovum perform these sepa- rate functions. The umbilical vessels of the chick ramify on the membrane of the albumen, and thus come in contact with the air, which is absorbed through the pores of the shell; and, by this contrivance, changes analogous to those effected by respiration, are produced on the blood. From the inner surface of the membrane of the vitellus, a nourishing fluid is absorbed which is conveyed to the intestine by a proper duct; and, before the chick is hatched, the remainder of this fluid, inclosed in the membrane of the vitellus, is taken within the abdomen, and covered with the abdominal integuments.1 In many quadrupeds we find, that, after impregnation, cer- * Vide Case by M. Anel, in Mem. of Acad, of Sciences, 1714. f This was proposed by Mauriceau, in consequence of meeting with an in- stance, where the child suffered much from loss of blood, obs. 256. ^ Vide Case by M. Degland, in Recueil Period, Tome V. p. 345. 101 tain portions of the inner surface of the uterus enlarge, and form protuberances, having many hollows or foramina, from which a milky fluid can be squeezed. From the chorion, cor- responding vascular efflorescences arise, which shoot into these apertures; and thus an union is effected betwixt the mother and foetus. In the sow and the mare there is no projection from the uterus, but its surface is every where smooth and vascular. There is no efflorescence from the chorion, but it has nu- merous vessels disposed over it, which are the extremities of the umbilical arteries and veins. In these animals, then, we have no distinct placenta, the chorion alone serving that purpose. The cetacea have uteri like quadrupeds, but I am unac- quainted with the precise mode of connection betwixt the mother and the foetus. The monkey differs from other quadrupeds, in having no permanent papilla ; but the maternal part of the placenta is deciduous, like that of women. In the human subject, the placenta is a flat circular sub- stance about a span in diameter, and, when uninjected, an inch in thickness. It becomes gradually thinner from the centre to the circumference, by which it ends less abruptly in the membranes. Its common shape is circular; but it is Sometimes oblong, or divided into different portions. The umbilical cord may be fixed into any part of the pla- centa, or sometimes into the membranes, at a distance from the placenta. When this happens, the vessels run in distinct branches to the placenta, without forming any spongy sub- stance on the membranes. Most frequently, however, the cord is inserted at a point about half way between the centre and the circumference of the placenta. From this the umbi- lical vessels spread out like a fan, ramifying over the surface, and dipping their extremities into the substance of the pla- centa itself. That surface of the placenta which is attached to the uterus, is divided into lobes, with slight sulci between them, and is covered with a layer of the decidua like clotted blood. vol. i. v 162 On the surface which is next the child, we see the eminent branches of the umbilical vessels, over which we find spread the chorion and amnion. If we inject, from the umbilical vessels of the human foetus, we find that the placenta is rendered turgid, and vessels arc to be found filled in every part of it; but always between their ramifications, there remains an uninjected substance; even the uterine surface of the placenta is not injected, for the foe- . tal vessels do not pass all the way to that surface. If we inject from the uterine arteries, we, in like manner, render the placenta turgid, but nothing passes into the umbi- lical vessels; and, when we cut into the placenta, we find cells full of injection, and covered with a fibrous uninjected matter. Hence we may infer, that the placenta consists uni- formly of two portions. The one is furnished by the deci- duous coat of the uterus, the other by the vessels of the cho- rion; and these two portions may, during the first three months, be separated, by maceration from each other. . The structure of the foetal portion, so far as we know, ap- pears to be similar to that of the pulmonary vessels, the arte- ry terminating in the vein. But the other portion is some- what different: there is not a direct anastomosis, but the artery opens into a cell, and the vein begins from this cell; for, by throwing in wax by the .uterine artery, we may fre- quently inject the veins. These cells communicate freely with each other in every part of the placenta, and may be compared to the corpora cavernosa penis. From the general principles of physiology, as well as from experiments on the chick in ovo, and from the fatal effects which instantly follow compression of the cord whilst the child is in utero, it is allowable to infer, that the placenta serves to produce a djange on the blood of the foetus, ana- logous to that which the blood of the adult undergoes in the lungs; and from considering, that the foetus itself cannot create materials for its own growth and support, we may farther infer* tha^t the placenta is the source of nutrition also. The placenta may be formed at any part of the uterus, but, in general, it is found attached near the fundus. 163 Its structure is sometimes changed, part of it being ossi- fied or indurated, or on the contrary, unusually soft. These changes may produce either hemorrhage, or retention of the placenta. Hydatids may form in the placenta; or fleshy tu- mours may grow in its substance. In neither of these cases does the child necessarily die. § 10. MEMBRANES AND LIQUOR AMNII. The ovum, when it descends into the uterus, consists of two membranes, one within the other, having very transpa- rent jelly interposed between them. But in process of time, the innermost, which is called the amnion, grows so much faster than the outermost, which is called the chorion, that it comes in contact with it, or at least has only a thin layer of jelly interposed. The amnion is thin, pellucid, and totally without the ap- pearance of either vessels or regular fibres; yet, in the end of pregnancy, it is stronger than the chorion and its vascular covering: it lines the chorion, covers the placenta, and mounts up on the navel string, affording a coat to it all the way to the umbilicus, where it terminates. The sac, formed by the amnion, is filled with a fluid, which appears to be composed chiefly of water, with a very little earth, mucus, and saline matter. As this water is contained within the amnion, it has received the name of liquor amnii. In this sac the foetus lies. The quantity of water, upon an average, which is contain- ed within the amnion, at the full time, is about two English pints; but sometimes it is much more, and at other times scarcely six ounces. In the early periods, the quantity is larger, in proportion to the size of the uterus, than after- wards. The chorion, like the amnion, is thin and transparent, ad- heres firmly to the placenta, and covers all the vessels which run on its surface ; but it does not dip down with them into the substance of the placenta. When the ovum first de- 164 scends, the chorion is every where covered with vessels, which sprout out from it. These form a covering to it, which, from its appearance, has been called the shaggy, or spongy chorion. § 11. DECIDUA. The last coat to be described, is one yielded entirely by the uterus, and serves to connect the uterus with the foetal vessels of the chorion. This, as Harvey observes, is not a covering of the foetus, but a lining of the uterus, which falls off after delivery; and therefore it is called the caducous coat, or the membrana decidua. The illustrious Haller supposed, that this was formed by naked vessels shooting out from the uterus. Dr. Hunter ima- gined, that the arteries of the uterus poured out coagulable lymph, which was afterwards changed into decidua. His brother, Mr. John Hunter, attributed its origin to coagulated blood, which formed a pulpy substance on the inner surface of the uterus. Having been so fortunate as to meet with three or four op- portunities of investigating the state of the uterus, within a month after conception, I shall describe what appears to me to be the structure of the decidua. Very speedily after im- pregnation, and always before the embryo enters into the womb, its size is increased, its fibres are softer and more separated from each other, and its vessels very much en- larged. On cutting it up, its cavity is found to be consider- ably broader and longer, and somewhat wider than in the un- impregnated state; and all the fundus and body have their surface covered with a dense coat, which adheres firmly to the uterus. If the vessels have been injected, this evidently is seen to consist of two different substances, namely vessels, and a firm tough gelatine. It seldom happens that all the vessels can he equally filled, and therefore some spots arc redder than "others. *The vessels do not pass on to the sur- face of this coatf bu| arc seen shining through it. They pro- 165 ceed directly from the surface of the wombj and project at right angles to the plane which yields them; they are inter- mixed with a little gelatine, and consist of both arteries and veins. Over their extremities is spread a layer of gelatinous matter, which very early is observed to contain fibres, form- ing a kind of net-work. Thus the decidua consists of two layers, one highly vascular, proceeding directly from the uterus ; the other, which is most probably formed by these vessels, is more fibrous and gelatinous; and when this is re- moved, the primary vessels, or outer layer, may he seen like a fine efflorescence, covering the surface of the uterus: in some cases the decidua extends a little into the fallopian tubes; in other instances it does not. In no case does the cervix form decidua. It is only produced by the fundus and body of the womb ; and immediately above the cervix, the decidua stretches across, so as to form a circumscribed bag within the uterus. In some instances, however, I have ob- served this continuation to be wanting, although the parts were opened with care. In all otiier circumstances, these uteri resembled those where the decidua was continued across; but, perhaps, notwithstanding this, there may'have been a difference of two or three days in the period of im- pregnation, occasioning this variation. In every case, the decidua, consisting thus of two layers, is completely formedC before the ovum descends. When the embryo passes down through the tube, it is stop- ped, when it reaches the uterus, by the inner layer which goes across the aperture of the tube, and thus would be pre- vented from falling into the cavity of the uterus, even were it quite loose and unattached. By the growth of the embryo, and the enlargement of the membranes, this layer is'distend- ed, and made to encroach upon the cavity of the uterus, or more correctly speaking, it grows with the ovum. This dis- tention or growth gradually increases, until at last the whole of the cavity of the uterus is filled up, and the protruded por tion of the inner layer of the decidua comes in contact with that portion of itself which remains 'a&ached to the outer layer. We find then, that the inner layer is'turned down 166 and covei's the chorion; from which circumstances* it has been called the reflected deciduals) Thus we see, that whenever the ovum descends, it is encir- cled by a vascular covering from the uterus, which unites, in every point, with those shaggy vessels which sprouted from the chorion, and which made what was called the spongy chorion. One part of these vessels forms placenta, and the rest gradually disappear, leaving the chorion covered by the decidua reflexa. This obliteration begins first at the under part of the chorion. CHAP. XVI. Of Sterility. Sterility depends either on malformation, or imperfect action of the organs of generation. In some instances the ovaria are wanting, or too small; or the tubes are imperfo- rated; or the uterus very small. In these cases the menses generally do not appear, the breasts are flat, the external organs small, or they partake of the male structure, and the sexual desire is inconsiderable. In a great majority of instances, however, the organs of generation seem to be well formed, but their action is imper- fect or disordered. The menses are either obstructed or sparing, or they are profuse or too frequent, and the causes of these morbid conditions have been already noticed. It is extremely rare for a woman to conceive, who does not (s) By others it is thus explained, viz. That after the cavity of the uterus is completely lined with the secreted decidua, the ovum passes into it from the fallopian tube, and in passing along its parietes, involves and covers it- self completely over every point of its surface with a coat of the decidua, which at that period may be compared to a coat of white paint; as the ovum increases in size, the decidua immediately covering it, (called decidua reflexa) ultimately comes in!b Intimate contact with that portion of the decidua, which continues to line the cavity of the uterus, and forms ap- parently but one membrane. 167 menstruate regularly; and on the contrary, correct menstru- ation generally indicates a capability of impregnation on the part of the woman. A state of weakness and exhaustion of the uterine system occasioned by frequent and promiscuous intercourse with the other sex, is another very common cause of barrenness in women, and hence few prostitutes conceive. A morbid state of the uterus and ovaria, often accompanied with fluor albus, may likewise be ranked amongst the causes of sterility, and this is known by its proper characters. Women who are very corpulent, are often barren, for their corpulence either depends upon want of activity of the ovaria, spayed, or castrated animals generally becoming fat, or it exists as a mark of weakness of the system. When sterility depends upon organic disease, we have it seldom in our power to remove it; but when there is no mark of the existence of such a state, and we have ground to suppose that it is occasioned by debility, or imperfect action of the uterine system, we are to employ such means as arc supposed capable of removing this, either by operating on it along with the general system of the body, or more directly on the uterus itself. Our first attention must be directed to menstruation, as the state of that function is our principal directory in the choice of the class of medicines to be em- ployed. On this subject I must refer to what has been said in chap. xii. We will also, altogether independently of the state of menstruation, naturally consider the condition of the constitution and habit of body, with regard to plethora, irri-, tability, torpor, or debility, and use varied and persevering means for rectifying those states ; always however, taking care that we do not injure the constitution in seeking for a remote good. In the majority of cases, weakness of uterine action is the cause, and the remedies are sea bathing and tonics, in various forms; general stimulants, such as bath waters, mercury, essential oils, nitrous acid, &c. when me- dicines of this description are not contra-indicated by the state of menstruation; local stimulants, which act more di- rectly on the uterus or its vicinity, as the semicupinm, can- 168 tharides, balsam of copaiba, &c. Of all these, the first class is the safest, and the most frequently useful. The ancients employed medicated pessaries, which have long fallen into disrepute, rather perhaps from the absurdity of their in- gredients, than from any argument respecting the inefficacy of gentle stimulants acting on the vagina and womb. A temporary separation from the husband is of service, es- pecially when the menses are profuse, and, in most cases, frequent intercourse should be avoided. Should a woman, who has been for some years barren, con- ceive, she must be very careful during gestation, for abortion is readily excited. In some cases, the uterine system is capable of being acted on by the semen of one person, but not of another. CHAP. XVII. Of Extra-uterine Pregnancy. § 1. SYMPTOMS, PROGRESS AND SPECIES. It sometimes happens, that the ovum does not pass down into the womb, but is retained in the ovarium, or stops in the tube, or is deposited among the bowels. Of all these species of extra-uterine pregnancy, the tubal is the most frequent. The symptoms of extra-uterine pregnancy are not, at first, •very definite; but generally the usual sympathetic effects of pregnancy, or the diseases of gestation, are more distressing than if the foetus were contained in utero, nor do they cease so early. In some cases, they even increase in violence, as pregnancy advances.* The symptoms, though often more violent, are, however, similar in kind, to those of common pregnancy. The belly swells, the uterus itself enlarges, and may be felt to be heavy; but, after some time, it docs not correspond in its size, and * Vide Paper by Dr. Garthshore, Lond. Med. Journ. Vol. VHI. &A4A. 169 in the state of its cervix, to the supposed period of gestation, or may return to the unimpregnated size.* The menses are often obstructed, though in some cases they have continued to appear for two or three months. The breasts enlarge, the morning sickness takes place about the usual period,1 and the child quickens at the proper time, but it is felt chiefly upon oiie side. An obstruction to the free passage of urine is some- times produced till the sac rise out of the pelvis. Occasionally in the early stage of pregnancy, pains2 resem- bling those of colic are felt, and these are often so severe as to excite syncope,3 or convulsions ;f and it has happened, that dining these pains, the tube or ovarium has burst, and the person died, owing to the internal hemorrhage. When these pains either do not occur, or are removed, we generally find, that at the end of eight, nine, or ten months from the com- mencement of gestation, appearances of labour4 take place; the woman suffers much from pain, and there may be a san- guineous discharge from the uterus. The pains go off more or less gradually,:}: the motion of the child ceases, and milk is secreted.^ In a few instances, very little farther inconve- nience is felt, the tumour of the belly remaining for many years, and the child being converted into a substance resem- bling the gras des cimetieres, whilst the sac which contains it becomes indurated. More frequently, however, considerable irritation is produced,|| inflammatory symptoms supervene, and hectic takes place. The sac adheres to the peritoneum, or intestines; and after an uncertain period, varying from a few weeks or months to several years, it either opens externally, or communicates with the abdominal viscera. Very foetid * Vide Mr. Tucker's case, Med. and Phys. Journ. xxix. 448. f Vide Dr. Fern's case, and a case by Mr. Jacob, in Lond. Med. Jour. Vol. VIII. p. 147. $ In Mr Bell's case, the pains continued, though gradually abating, for three weeks. Med. Comment. Vol. II. p. 72. §In Mr. Bell's case, milk continued to be secreted for several years. In Mr. Turnbull's case, a fluid was secreted, rather like pus than milk. ' i| In the case of a female mulatto, the outlines of wliich 1 was favoured with by Dr. Chisholm, the pain was so great that, it could not be. allayed by the strongest opiates. It endpd fatally. VOL. T. 7. 170 matter, together with putrid flesh, bones, and coagula are dis- charged through the abdominal integuments,* or by the rec- tum,5 vagina,6 or bladder.7 Sometimes, even an entire foetus has been brought away from the umbilicus,8 or by the rectum.' It is worthy of notice, that the placenta, in this process, al- ways is ultimately destroyed,10 and discharged among the putrid fluid. Often, time is not allowed for this process to he accomplished, but the person dies at an early period. Thus it appears, that there are different terminations of the extra-uterine pregnancy. The sac may burst, and the person die speedily of hemorrhage;11 or the child may escape into the abdomen, and be enclosed in a kind of cyst of lymph ;f or the sac may remain entire, the child being retained many years,12 and the parts become hard; notwithstanding this, the menses may return, and the woman conceive again.13 But the most frequent termination is that of inflammation ending in abscess, attended with fever and pain, under which the patient either sinks, or the foetus is expelled in pieces, and the cure is slowly accomplished. From a review of cases it appears, that a majority ultimately recover, or get the bet- ter of the immediate injury: of the rest, some have sunk speedily, either from hemorrhage or inflammation, or ex- haustion produced by ineffectual attempts to expel the child; or more slowly from hectic fever; or in consequence of some other disease being called into action, by the violence which the constitution has sustained. In some cases the sac soon rises quite out of the pelvis. In others, it remains longer and falls down between the rec- tum and vagina, forming a tumour, accompanied with symp- toms of retroversion14 of the uterus.}: In such cases, the sac inflames, and bursts into the rectum or vagina. Dr. Merri- man§ is of opinion, that all these cases are instances of retro- verted uterus, and not of extra-uterine pregnancy; but, for the present, this must rest entirely on supposition. The • This termination is noticed so long ago as by AlbuGasis, lib. II. c. 76. j- Vide a case by La Croix, in La Med. Eelaree, Tome. IV. p. 349. $ Vide Mr. Mainwarring's case, in Trans, of a Society, &c. Vol. U. p. 287. § Vide Dissert on Retroversion, &c. 1810. 171 mere circumstance of the pregnancy being complicated with suppression of urine, or tumour at the back part of the pelvis, is no proof; as both of these may arise from the pressure of the sac on the pelvis. Sometimes, when parturient efforts are made, the head de- scends into the pelvis, though it was not there before ; but either no os uteri can be felt, or it is felt directed to the pubis, and it is not affected by the pains.(i) It is curious to observe, that generally the uterus enlarges somewhat,15 and in most instances, I imagine, decidua16 is formed. In a remarkable case, related by the ingenious Mr. Hay* of Leeds, the placenta was formed in the uterus, while the foetus lay in the tube. Tubal pregnancy sometimes does not proceed farther than the second month, the tube bursting atthat time ; or, to speak more correctly, I believe the tube slowly inflames, and slough- ing takes place. In a great majority of instances, however, the tube goes on enlurging for nine months, and acquires a size nearly equal to that Of the gravid uterus, at the same stage of gestation.f T"ie placenta differs from a uterine placenta in being much thinner and more extended. Exter- nal examination discovers little difference, at the full time, between this and common pregnancy. Ovarian17 is much more rare than tubal pregnancy, and it is seldom that the ovarium acquires a great size. It either bursts early,18 or inflammation and abscess take place; or the foetus dies, and is converted into a confused mass; or it excites dropsy of the ovarium.19 The ovarian pregnancy, until inflammation has taken place, produces a circumscribed moveable tumour, like dropsy of the ovarium. (<) It is very probable that some of these cases have in reality originated from retroversions of the uterus, which, as Merriman has proved, may even continue in that state until the full period of utero-gestation. This subject shall be more fully explained, when retroversion of the uterus comes to be treated of. In the meantime the student is referred to a review of Dr. Mer- riman's Work, in the Eclectic Repertory, Vol. I. p. 338. * Vide Med. Obs. and Inq. Vol. III. p. 341. f Among many other cases, in proof of this, I may refer to one very accu- rately detailed by Dr. Clarke, in the Trans, of a Society, 8ic. Vol. II. p. 1. 172 In ventral pregnancy, the most rare of the three species, the motions of the child are felt more freely, and its shape is readily distinguished through the abdominal integuments: The expulsive efforts come on as usual, and the head of the child is sometimes forced into the pelvis. It dies, and the usual process for its removal is carried on, if the woman do not sink immediately under the irritation. The placenta is found attached to the mesentery or intestines.20 It has been supposed, that the examples of this variety are all in reality instances of ruptured uteri: but this is not supported by satisfactory proof. At the same time, I have no doubt that many of them are. § 2. TREATMENT In the treatment of extra-uterine pregnancy, mucn must depend on the circumstances of the case. In the early stage, if the sac be lodged in the pelvis, we must procure stools, and have the bladder regularly emptied, as in cases of retrovert- ed uterus. Attacks of pain during the enlargement of the tube, require blood-letting and anodynes, laxatives and fomen- tations. The same remedies are indicated when convulsions take place. Ovarian requires a similar management with tubal pregnancy, except that if it be complicated with dropsy, relief may be obtained by tapping. When expulsive efforts are made, and the head is felt through the vagina, and the nature of the case distinctly as- certained, it may be supposed, that much suffering may be avoided, by making an incision through the vagina, and de- livering the child; but, as yet, experience has not fully ascer- tained the utility of this practice.* It has been proposed, in these and other circumstances, to perform the csesarean operation,! in the usual manner, upon the accession of labour; ~ * In a case, probably of this kind, related by Lauverjat, and quoted by Saba. < tier, the child was extracted by an incision through the vagina, and the woman recovered. De la Med. Operat. Tome. I. p. 136. | M. Colomb, performed the cesarean operation, but it ended fatally. Re- cueil des Actes de la Society de Lyon. 173 but there is not only great danger from the wound, but like- wise from the management of the placenta, which if removed, may cause hemorrhage, especially in ventral pregnancy, and, if left behind, may produce bad effects. The last, however, is the safest alternative. The result of the numerous cases upon record, will certain- ly justify, to the fullest extent, our trusting to the powers of nature rather than to the knife of the surgeon. Allaying pain and irritation in the first instance, by blood-letting, anodynes, and fomentations; and avoiding, during all the in- flammatory stage, stimulants and motion, whilst, by suitable means, we palliate any particular symptom, constitute the sum of our practice. A tendency to suppuration is to be encouraged by poul- tices ; and the tumour, when it points externally, is either to be opened, or to be left to burst spontaneously, according to the sufferings of the patient, and the exigencies of the case.21 The passage of the bones, and different parts of the foetus, may often be assisted; and the strength is to be supported un- der the hectic which accompanies the process. After the abscess closes, great care is still necessary, for, by fatigue or exertion, it may be renewed, and prove fatal.22 When no process is begun for removing the foetus, but it is retained and indurated, our practice is confined to the pallia- tion of such particular symptoms as occur. CHAP. XVIII. Of the Signs of Pregnancy. Some women feel, immediately after conception, a particu- lar sensation, which apprizes them of their situation; but such instances are not frequent; and, generally, the first circum- stances which lead a woman to suppose herself pregnant, are the suppression of the menses, and an irritable, or dyspeptic state of the stomach. She is sick or vomits in the morning, 174 and has returning qualms or fits of languor during the fore- noon; is liable to heartburn through the day or in the even- ing, and to that disturbed sleep through the night, which so frequently attends abdominal irritation. In some instances, the mind also is affected, becoming unusually irritable, change- able, or melancholy. The breasts often at first become smaller, but about the third month they enlarge, and occa- sionally become painful; the nipple is surrounded with a browrn circle or areola; and often, even at an early period, a serous fluid begins to ooze from it, The woman loses her looks, becomes paler, and the under part of the lower eye-lid is of a leaden hue. The features become sharper, and some- times the whole body begins to be emaciated, whilst the pulse quickens. In many instances, particular sympathies take place, causing salivation, tooth-aeh, jaundice, &c. In other cases, very little disturbance is produced, and the woman is not certain of her condition, until the period of quickening. In the commencement of pregnancy, the abdomen does not become tumid, but, on the contrary, is often rather flatter than formerly; and, when it does first increase in size, it is rather from inflation of the bowels, than from expansion of the uterus. As an increase of bulk, together with many of the other symptoms of gestation, may proceed from suppres- sion of the menses, we cannot positively, from those signs, pronounce a woman to be with child. The enlargement of the belly is at first accompanied with tension or uneasiness about the navel, which soon becomes rather prominent. When women have any doubt, with regard to their situa- tion, they generally look forward to the end of the second quarter of pregnancy, as a period which can ascertain their condition. For, at this time, or a little sooner or later, in different woman, the uterus ascends out of the pelvis, and the motion of the child is first perceived, or it is said to quicken :(u) and, in some cases, a few drops of blood flow «!•$(") Professor Roederer kept a correct account of one hundred women, noting the time when it was presumed they were impregnated, the period at which they quickened, and again, the time when they were delivered. %ut oftliis number we are informed, that eighty quickened at the fourth month, 175 from the uterus at this period. The motion is first felt in the hypogastrium, and is languid and indistinct, but by degrees it becomes stronger. It is possible for women to mistake the effects of wind for the motion of a child, especially if they have never borne children, and be anxious for a family. But the sensation produced by wind in the bowels is not confined to one spot, but very often is referred to a part of the abdo- men, where the motion of the child could not possibly be felt. It is not to be supposed, that the child is not alive till the period of quickening, though the code of criminal law is ab- surdly founded on that idea. The child is alive from the first moment that it becomes visible, but the phenomena of life must vary much at different periods. The child is not a portion of the remainder quickened at the third month, and the rest went on to the fifth. Therefore, we may with great propriety consider four months as the general time of quickening; and upon finding that a woman has quickened, within a day or two, we may with great confidence calculate that she has five months to go. The term quickening, is certainly not the most accurate phrase that could be selected, to express the simple fact of the uterus rising above the brim or cavity of the pelvis. It is well known, that the impregnated uterus generally remains in the pelvis, as we have just observed, until the latter part of the fourth month; and that after this period, as it enlarges, it necessarily rises above that cavity into the abdomen : but it is to be remarked, 1. The ascent of the impregnated uterus from its position in the pelvis to its subsequent station, is sometimes gradual and unobserved; of course, the sensation of quickening is not then felt. 2. The uterus is sometimes so impacted in the cavity of the pelvis, as not to reach its final station within the abdomen without the assistance of art, producing the disease called retroverted uterus, during which, quickening is never felt 3. At other times, and those frequent, though not constant/there exists some slight impediment to the ascent of the uterus, -uldch being suddenly over- come, tfiis viscus rises at once into the abdominal cavity, constituting what lias been referred to the foetus, under the term qtrickening. The sudden intrusion, therefore, of the volume of the uterus among th« abdominal viscera, accompanied by as sudden a removal of pressure from the ihac vessels, is supposed to be equal to produce the sensation we have above -A< noticed. '• ^, We may then state, "That the sensation of quickening is felt in transitu, at the moment when the uterus, removing from the pelvis, enters the abdo- minal cavity." Vide Eclectic Repertory, Vol. III. p. 30 October. No. IX. < 176 felt to move till after the ascent of the uterus out of the pelvis. Does this arise from any change in the phenomena of life at that time in the child itself, or from the muscular power be- coming stronger, or from the uterus now being in a situation, where there being more sensibility, the motion is better felt? All of these probably contribute to the sensation which be- comes stronger, as the child acquires more vigour, and as the relative proportion of liquor amnii decreases. This foetal motion, however, is not to be confounded with the sensation felt by the mother from the uterus rising out of the pelvis, and which precedes the feeling of fluttering. If this eleva- tion shall take place suddenly, the sensation accompanying it is pretty strong^'and the woman at the time often feels sick or faint, and in irritable habits, even an hysterical fit, may attend it. From the time when this is felt, women are said to have quickened, and they afterwards expect to he conscious of the motion of the child. The morning sickness, and many of the sympathetic effects of pregnancy, generally abate after this, and the health improves during the two last quarters. Many women suppose, that, by examining the blood drawn from the veins, their pregnancy may be ascertained. Very soon after impregnation, the blood becomes sizy; but it differs from the blood of a person affected with inflammation. Ill the latter case, the surface of the crassamentum is dense, firm, and of a buff colour, and more or less depressed in the centre. But in pregnancy the surface is not depressed, the coagulum is of a softer texture, of a yellow, and more oily appearance. It is not possible, however, to determine posi- tively, from inspecting the blood; for a pregnant woman may have some local disease, giving the blood a truly inflamma- tory appearance; and, on the other hand, it is possible for the suppression of the menses, accompanied with a febrile state, to give the blood the appearance which it has in preg- nancy. Examination of the uterus itself is a more certain mode of ascertaining pregnancy. About the second month of gesta- tion, the uterus may be felt prolapsing lower in the vagina than formerly; its mouth is not directed so much forward as 177 before impregnation ; it is shut up, and the cervix is felt to be thicker, or increased in circumference. When raised on the finger, it is found to be heavier, or more resisting. Some have advised, that the os uteri should be raised upward and forward, so as to retrovert the womb, in order that its body may be felt, but this is not expedient. Examination, at this period, is liable to uncertainty, because the uterus of one woman is naturally different in magnitude from that of an- other. But in the third month we can arrive at tolerable certainty, the womb being then felt decidedly to be heavier, and more easily balanced on the finger. In the beginning of the fifth month it is found to be higher than when unimpreg- nated ; a kind of fluctuation may be perceived, and by placing the hand on the lower part of the belly, so as to press on the fundus of the womb, it can be made to give more resistance to the finger applied per vaginam, and may by it be rolled about. After quickening, if we pat with the finger on the cervix uteri, we can generally make the child strike gently, so as to be felt. About this time, and still more distinctly afterwards, we can, if the abdominal muscles be relaxed, feel the uterus extending up from the symphysis pubis, and^in proportion as pregnancy advances, can more readily distinguish the members of the child, and feel its jerks or motions. Ex- amination, per vaginam, informs us of those changes of the cervix and os uteri, which were noticed in a former chapter. CHAP. XIX. Of the Diseases of Pregnant Women. § 1. GENERAL EFFECTS. Pregnancy produces an effect on the general system, marked often by a degree of fever, and always by an altered state of the blood. This state is the consequence of local increased action, which irritates and excites the system, in vol. J. * * 178 the same way as when an organ is inflamed. There would appear to be, likewise, a tendency to the formation of more blood than formerly, and the nervous system is evidently rendered more irritable. The gravid uterus, also, has an effect by sympathy, on other organs or viscera; and likewise produces changes in them, mechanically, by its bulk and pressure. The effects of pregnancy vary much, both in degree, and in the nature and combination of the symptoms, according to the constitution of the woman, and the natural or acquired irritability of different organs. In a few cases, a very salu- tary change is produced on the whole system, so that the person enjoys better health during pregnancy, than at other times. But in most instances, troublesome or inconvenient symptoms are excited, which are called the diseases of preg- nancy, and which in some women, proceed so far, as not only to deprive them of all enjoyment and comfort, but even to produce considerable fear of their safety. As these proceed from the state of the uterus, it follows, that when they exist in a moderate degree, they neither admit of, nor require any attempts to cure them ; for their removal implies a stoppage of the action of gestation, which is their cause. But when any of the effects are carried to a troublesome extent, then we are applied to, and may palliate, though we cannot take them away. This we do by lessening plethora, if necessary, by blood-letting, and allaying the increased irritability of the system by the regular use of laxa- tives, which remove that particular state of the bowels, which is so apt to cause restlessness and nervous irritation. If these are not altogether successful, the camphorated julap, is a use- ful medicine.* Besides this general plan, we must diminsh • Petit, and many after him, have been of opinion, that opium is hurtful during gestation; and there can be no doubt that it generally is so when given frequently. It is detrimental, both by its effects upon the stomach and bowels, and on the system at large. In severe spasms, or great irrita- tion, it may be necessary, but it sever ought to be often repeated, as it ulti- mately increases the irritability and injures the bowels, as it would do in chorea. 179 the febrile state of the system, where such exists, by regula- tion of the diet, and suitable remedies. Individual symptoms must be treated on general principles. There is a great diversity, both in the effects of pregnancy, and also in the period at which these manifest themselves; for whilst some begin to suffer very early from the irritation of the uterus, and are much relieved from the effects thereof after the child quickens, others feel very little inconvenience till towards the end of pregnancy, or the last quarter, when the womb is greatly enlarged, and the abdominal viscera dis- turbed. § 2. FEBRILE STATE. In many cases, the pulse becomes somewhat quicker soon after impregnation, and the heat of the skin is at the same time a little increased, especially in the evenings. In the later months of pregnancy, the febrile symptoms in some in- stances are extremely troublesome; the pulse is permanently frequent, but in the evenings it is more accelerated, whilst the skin becomes hot, and the woman restless; she cannot sleep, but tosses about till day-break, when she procures short unrefreshing slumber, occasionally accompanied with a partial perspiration. In the morning, the febrile symp- toms are found to have subsided; but in the afternoon they return, and the following night is spent alike uncomfortably. This state is attended with more emaciation, and greater sharpness of the features, than is met with in pregnancy, un- der different circumstances, but it is wonderful how well the strength is kept up in spite of the want of rest, and of the uneasiness which is produced, from this disease being some- times conjoined with intolerable heat about the parts of gene- ration. In slight degrees of this febrile state, all that is necessary is sedulously to keep the^bowels open, and take away a little blood. But when it becomes urgent towards the last months of gestation, we are under the necessity of taking away blood more frequently, but not in great quantity at a time. 18G The saline julap is of considerable service, by producing a gentle moisture, but a copious perspiration is neither neces- sary nor useful. The julap may either be given in repeated doses through the day, or merely one or two doses in the morning, or early part of the night according to circum- stances. The bowels are to be kept open by a mild laxative, such as the alcotic pill, or rhubarb and magnesia. The sulphuric acid is a very good internal medicine. The rest- lessness is best allayed by sleeping with few bed-clothes; and sometimes great relief is obtained, by dipping tiie hands in water, or grasping a wet sponge. Opiates very seldom give relief, and ought not be pushed far, as they make the woman more uncomfortable, and are supposed even to injure the child; at all events, if the occasional exhibition, on any emergency, of a moderate dose of opium or hyocyamus, fail to procure comfortable sleep, no benefit is to be expected from increasing the quantity. Frequently nothing does much good, the state continuing until the woman is delivered. There is a species of fever, which may affect women about the middle of pregnancy, and makes its attack suddenly, like a regular paroxysm of ague. It soon puts on an appearance rather of hectic, combined with hysterical symptoms. The head is generally at first pained, or the patient complains of much noise Within it, sleeps little, has a loathing at food, with a foul dry tongue, and a considerable thirst, whilst the bowels are constipated. Sometimes she talks incoherently, or moans much during her slumber, and has frightful dreams: occasionally a cough, or distressing vomiting supervenes. This disease is very obstinate, and often ends in abortion; after which, if the woman do not sink speedily under the ef- fects of the process, she begins to recover, but remains long in a chlorotic state, which if not removed, may terminate in phthisis. I strongly suspect that this disease originates from the bowels, and bears great analogy to the infantile remitting fever. It is usually preceded by costiveness, and is some- times apparently excited by irregularities in diet. We ought on the first attack of the cold fit to check it by warm dilu- ents, with the saline julap. If the proper opportunity be lost, 181 or these means fail, we must lessen irritation by detracting some blood ; open the bowels freely, and afterwards prevent feculent accumulation, keep the surface moist, and palliate troublesome symptoms. If the tongue be early loaded, and the patient is sick or squeamish, a very gentle emetic w ill be proper. The strength is to be supported. In a state of con- valescence, gentle exercise and pure air are useful, but every exertion must be avoided. § 3. VOMITING. Vomiting is a very frequent effect of pregnancy, and occa- sionally begins almost immediately after conception. Gene- rally it takes place only in the morning, immediately after getting up, and hence it has been called the morning sick- ness, but in a few instances, it does* not come on till the af- ternoon. It usually continues until the period of quickening, after which it decreases or goes off, but sometimes it remains during the whole of gestation. Some women do not vomit, and have very little if any sickness; others begin, after the fourth month, to feel an irritation about the stomach and other viscera ; and some remain free from inconvenience till the conclusion of pregnancy, when the distension of the womb affects the stomach. The fluid thrown up is generally glary or phlegm, and the* mouth fills with water previous to vomiting; but if the vomiting be severe or repeated, bilious fluid is ejected. Generally there is no occasion to prescribe any remedies. Puzos, and others, even considered vomiting as salutary; but in some cases, it goes to a very great length, recurring whenever the woman eats, or sometimes even when she abstains from eating, and continues for days or even weeks so obstinate, that she is in danger of miscarrying,* or of suf- fering from want of food. It is a general rule, in such cases, to take away early a small quantity of blood, a quantity pro- portioned to the vigour and fulness of the habit and state of the * It is worthy of remark, that abortion is very seldom occasioned by this cause, though emetics arc apt to produce it 182 pulse. Of the utility of this practice, the general testimony of practitioners, and my own observation, fully convince me. Narcotic substances, such as opium or hyocyamus, have been tried internally, either without blood-letting or subsequent to it, but uniformly with little advantage. In a few instances, a cloth wet with laudanum applied to the pit of the stomach has done good. The greatest attention must be paid to the bowels, and most marked benefit is often derived from a gentle dose of Epsom or Cheltenham salts. The severity of the vomiting may also be greatly mitigated by effervescing draughts, or soda water: the last of which, if it do not check the vomiting, renders it much easier. Even cold water has been employed with advantage. A light bitter infusion is sometimes of service. Obstinate vomiting, especially if ac- companied with pain, or tension in the epigastric region, may be relieved by the application of leeches to that part, which have been much recommended by Dr. John Sims, and M. Lorentz. I have so often found advantage from this remedy, that I speak of it with confidence. If these means fail in pro- curing speedy relief, it is necessary to refrain for a time eat- ing, and have recourse to nourishing clysters, or to give only a spoonful of milk, soup, &c. at a time. When the vomiting is bilious, and accompanied with pain in the right side and shoulder, cough, and other symptoms of hepatitis, a seton should he immediately introduced into the side, and a very gentle course of mercury given; for if the medicine be given freely, it produces much debility, or abortion, and sometimes accelerates the fate of the patient. When vomiting is troublesome in the conclusion of preg- nancy, it is proper to detract blood; and confine the person to bed. Cloths, dipped in laudanum, should be applied to the pit of the stomach, and a grain.of solid opium may be given internally; but if this do not succeed, it is not proper to give larger and repeated doses. Gentle laxatives must be employed. k 18.3 § 4. HEARTBURN. Heartburn often takes place very early after conception, but sometimes not till after the fourth month. This is a complaint so very common, and so generally mitigated by absorbents, such as magnesia or chalk, that we are seldom consulted respecting it. But when it becomes very severe and intractable, it is requisite to try the most powerful of these means, such as calcined magnesia, combined with pure ammonia.(a?) When these fail, soda water, or the chalk mix- ture, with a large proportion of mucilage, may give relief. Laxatives are alw ays indispensable. In obstinate cases, vene- section is useful. Emetics have been proposed by Dr. Den- man, but they may sometimes cause abortion. They are only allowable where there is a constant screatus of disagreeable phlegm. In every severe case the diet must be carefully attended to. Pyrosis is to be relieved chiefly by laxatives, such as the aloetic pill or rhubarb and magnesia, and rubbing the epigas- tric region with anodyne balsam. § 5. FASTIDIOUS TASTE. Women, during gestation, are subject to many bizarreries in their appetite, and often have a desire to eat things they did (a:) The late much regretted Dr. Young, of Maryland, in his ingenious ex- periments on the digestive process, has almost reduced it to a certainty, that the acid which exists in the stomach is to be referred to the liquor gastricus; that it is the phosphoric acid, and that the acidity of dyspeptic and pregnant women, is owing to the morbid quantity of this acid. Hence, as he justly re- marks, the superiority of hme water as a corrector, from its great affinity to phosphoric acid. The following formula is also recommended by experienced practitioners for the same purpose. I have used it with advantage. $». Magnesia ustse 3j- Aqua purse 5VSS- Sp. Cinnamon giij. Aquae Ammoniac purx ^j m- Two or three spoonsful to be taken either occasionally, or when the symp- toms are more continual, immediately after every meal. 184 not formerly like. This desire is common in cases of abdo- minal irritation, as we see in those who are afflicted with worms, or have indurated or morbid faeces in the intestines. These longings, it has been thought dangerous to deny ; for as it was supposed, that they depend upon some peculiar state of the child affecting the mother, it was imagined, that if this was not removed, the infant would sustain an injury, or might even bear the mark of the thing longed for. Into this doctrine, it is now unnecessary to enter, and it will be sufficient to add, that when the desire is placed upon any article of diet, it may be safely gratified, and, indeed, gene- rally the inclination leads to some light and cooling regimen. § 6. SPASM OF THE STOMACH AND DUODENUM. Spasm of the stomach, or duodenum, may often be attri- buted to some irregularity of diet, to the action of cold, or to the influence of the mind. It is necessary to interfere promp- ly, not only because the pain is severe, but also because it may excite abortion, or kill the child. A full dose of lauda- num, with ether, followed immediately by a saline clyster, is almost always successful; but when the attacks are. re- newed, then we must endeavour to prevent them by tonics, such as colomba, oxyde of bismuth, or preparations of steel. It is at the same time, essential that the bowels be kept open. Blood-letting is of service. When spasm of the stomach takes place in the end of preg- nancy, or about the commencement of parturition, with a sense of fulness or uneasiness in the head, it is necessary to detract blood, lest the patient be seized with convulsions. This re- medy is likewise proper, when the pain is accompanied with tenderness about the epigastric region, heat of the skin, full pulse, and ruddy face. When pain proceeds from the pas- sage of a biliary calculus, it is to be treated more solito. $ 7. COSTIVENESS. Costiveness is a general attendant on pregnancy, partly owing to the pressure of the uterus on the rectum, and partly 185 owing to the increased activity of the womb producing a slug- gish motion of the bowels. We must not, however, neglect this state, because it naturally attends gestation, for it may occasion many and serious evils. It certainly increases the irritability of the system, as well as some of the stomachic ailments; and is apt to cause irritation of the bowels, which may either excite premature labour, or give rise to much inconvenience after delivery, and not unfrequently occasions convulsions. Magnesia is a very common remedy, because it at the same time relieves heartburn; but, when it fails, or is not required for curing acidity in the stomach, the common aloetic pill, or a combination of aloes with extract of hyoscyamus, should the former gripe, may be employed. Castor oil is also given, either alone, or made into an emulsion with mucilage. It sometimes happens that indurated faeces are accumu- lated in the rectum or colon, producing considerable irrita- tion. This causes not only pain, but also an increased secre- tion of the intestinal mucus, which is passed either alone, or with blood, together with pieces of hard faeces. This state, like dysentery, is often accompanied with great tenesmus ; but it may be readily distinguished, by examining per vagi- nam, for the rectum is found to be filled with faeces. Our first object ought to be to remove the irritating cause, which might ultimately produce abortion. Clysters are of great efficacy, because they soften the faeces, and assist in emptying that part of the intestine which is most distended. These are to be, at first, of a very mild nature, and must be frequently repeated. It may even be requisite to break down the fecu- lent mass, with the shank of a spoon, or some such instru- ment.^) After the rectum is emptied, laxatives, such as castor oil, or small doses of sulphate of magnesia must be given to evacuate the colon; and when the faeces are brought (y) The reader is referred, for a very interesting case of alvine concre- tion, where it became necessary to introduce a long flexible catheter through the hardened and impacted faeces, occupying the superior part of the pelvis, for the purpose of injecting an enema, to Hey's Practical Oservations on Surgery, chap. XVIII. case 3. VOL. I. U IS / 180 into the rectum, clysters must be again employed. After the bowels are emptied, hyoscyamus should be given, to allay the irritation; or if this be not sufficient, and the pain and secre- tion of mucus, with tenesmus, still continue, an opiate must be administered, but next day it is to be followed by a mild laxative. And if there be fever or considerable pain in the abdomen blood-letting will be necessary. If this costive state be neglected near the time of delivery, the labour is often protracted ; and after delivery masses of indurated faeces come down from the colon, producing considerable pain and frequency of pulse. When there is much irritation and sen- sibility, upon pressing on the abdomen, either before or after delivery, it will be proper to detract blood, at the same time that we use the remedies already pointed out. § 8. DIARRHOEA. The bowels, instead of being bound, may be very open; or costiveness and diarrhoea may alternate with each other. The diarrhoea is of two kinds; a simple increase of the peristaltic motion, and increased serous secretion; or a more obstinate disease, depending on debilitated and deranged action of the bowels. In the first kind, the discharge is not altered from the natural state, except in being thinner; the appetite is pretty good, and the tongue clean, or only slightly white. This is not to be checked, unless it go to a consider- able extent, or continue long, or the patient be weakened by it, or be previously of a debilitated habit. Anodyne clysters, or the confectio catechu, will then be of service. Should the pulse be frequent, and any degree of heat or tension be felt in the abdomen, venesection will be useful. In the second kind, the appetite is lost or diminished, the tongue is foul, and the patient has a bitter or bad taste, and occasionally .vomits ill tasted or bilious matter; the breath is offensive, and often the head aches. The stools are very offensive, and generally dark coloured. In this case, small doses of rhu- barb give great relief, and one grain of ipecacuanha may oc- casionally be added to each dose of rhubarb. A light bitter 187 infusion is also a useful remedy. Attention must be paid to the diet, which is to be light, and the food taken in a small quantity at a time. Considerable benefit is derived from soda water, which generally abates the sickness. When the tongue becomes cleaner and the stools more natural, anodyne clysters may be administered. In all cases of continued diarrhoea, it is useful to have the surface kept warm with flannel; and sometimes a flannel roller, bound gently round the abdomen, gives great relief. § 9. PILES. Pregnant wTomen are very subject to piles. This may be partly owing to the pressure of the womb upon the vessels of the pelvis, but is chiefly to be attributed to a sluggish state of the intestinal canal, communicating a similar torpor to the hemorrhoidal veins. As this state is attended with costive- ness, the disease has been considered as dependent on the mechanical action of the faeces; but whatever truth may be in this opinion in some cases, yet generally it is without foundation ; and it is no unusual thing for those who are subject to piles, to be able to foretell an attack, by the ap- pearance of peculiar symptoms, indicating diminished action of the alimentary canal. The treatment of this disease is two-fold. We are to remove the cause by such means as give a brisker action to the bowels such as bitters and laxatives ; which last are also of great service by removing the irrita- tion of the faeces from the rectum, and rendering them softer, by which the expulsion gives less pain. For this purpose, cream of tartar alone, ob combined with sulphur, has been generally employed; but we may, with equal advantage, give small doses of castor oil, or of any of the mild neutral salts, dissolved in a large quantity of water. Besides removing the cause, we must likewise lessen the effect by such local means as abate irritation and sensibility. When the pain, inflammation, and swelling, are great, it is of service to de- tract blood topically, by the application of leeches, or, espe- cially if there be considerable fever, blood-letting may b« 188 necessary, as in other cases of local inflammation. The diet should be spare; all stimulants and cordials must be avoided ; cooling and anodyne applications to the tumour are also very proper, such as an ointment containing a small quantity of acetate of lead, or a weak solution of the acetate of lead in rose water, or a mixture of the acetum lithargyri and cream. Sometimes astringents are of service, such as the gall ointment; or narcotics, such as opium* or belladona. If these means fail, it will be proper to give an anodyne clyster, and apply fomentations or emollient poultices to the tumour, but e^evy practitioner can tell how often all topical applica- tions have disappointed him. In some cases, the tumour be- comes slack, and subsides gradually; in other instances it bursts, and more or less blood is discharged. If the hemorr- hage be moderate, it gives relief; but if profuse, it causes weakness, and must be restrained by pressure and astrin- gents. Great pain, or much hemorrhage, are both apt to excite abortion. § 10. AFFECTIONS OF THE BLADDER. The bladder is often affected by pregnancy. In some in- stances like the intestines, it becomes more torpid than for- merly ; so that the woman retains her water long, and expels it with some difficulty, and in considerable quantity at a time. This state requires great attention, for retroversion of the uterus may, at a certain stage of gestation, be readily occa- sioned. There is not much to be done with medicines in this case; for, although soda, and similar remedies, sometimes give relief, yet more reliance must be placed on the regular efforts of the patient. Should these be delayed too long, then the catheter must be employed. More frequently the bladder is rendered unusually irritable, especially about its neck, and the urethra participates in this * Dr. Johnson advises the following ointment to be apphed, and then a poultice to be laid over the tumour. R. 01. Amygd. 5i. 01. Succini §ss. Tr. Opii.3«. M. System?. US. 189 state. There is also, in many instances, an uneasiness felt in the region of the bladder itself. This state requires a very different treatment from the former, for here it is our object to avoid every saline medicine which might render the urine more stimulating. Relief is to be expected by taking away blood, giving small doses of castor oil, and, occasionally, the extract or tincture of hyoscyamus, and encouraging the pa- tient to drink mucilaginous fluids, which, if they do not reach the bladder as mucilage, at least afford a bland addition to the blood, from which the urine is secreted. This state of the bladder is sometimes productive of a light irritation about the symphysis of the pubis, rendering the articulation less firm and more easily separated. In such circumstances, when the pubis is tender, blood-letting and rest are the two principal remedies. A very distressing affection, which is often conjoined with this state of the bladder and urethra, but which may also take place without it, is a tender and irritable state of the vulva, producing great itching about the pudendum, especially dur- ing the night, and generally the urine is felt very hot. This distressing condition is often alleviated by blood-letting and laxatives; and when the itching is great, a sponge, dipped in cold water, or in cold solution of cerussa acetata, should be applied. If much fever exist, the saline julap, combined with a little tincture of opium, is useful. Incontinence of urine is not uncommon, in the end of ges- tation, and is produced by the pressure of the uterus on the bladder, by which the urine is forced off involuntarily, when- ever the woman coughs or moves quickly; or at least she can- not retain much of it, being obliged to void it frequently, but without strangury. For this complaint there is no cure; and many consider it as a favourable omen, that the child's head is resting on the os uteri. When the uterus is very pendulous, some advantage may be obtained, by supporting the belly with a proper bandage attached to the shoulders. 190 § 11. JAUNDICE. Connected with the state of the alimentary canal, is the jaundice of pregnant women. This disease appears at an early period, and is preceded by dyspeptic symptoms, which generally increase after the yellowness comes on. In some instances, the tinge is very slight, and soon disappears. In other cases, the yellow colour is deep and long continued, and the derangement of the stomach and bowels considerable. Emetics, and other violent remedies, which are sometimes used in the cure of the jaundice, are not allowable in this ease, and in every instance, when young married women are seized with jaundice, we should be very cautious in our pre- scriptions. Gentle doses of calomel, or of other laxatives, with some light bitter infusion, are the most proper remedies; and generally the complaint soon goes off. Jaundice may also take place in the end of gestation; and in this case, it proceeds most frequently from pressure on the gall duct. Sometimes, however, it is dependent on a disease of the liver itself, which may occur at any period of gestation, and is marked by the usual symptoms. In this case the danger is very great, and can only be averted by taking cautious mea- sures for removing the hepatic disease. §*12. COLOURED SPOTS. In some cases, the skin is partially coloured; the mouth, for instance, being surrounded with a yellow or brown circle, or irregular patches of these colours appearing on different parts of the body. This is an affection quite independent of the state of the bile, and seems rather to be connected with certain conditions of the alimentary canal. It goes off after delivery, and does not require any peculiar treatment. § 13. PALPITATION. The thoracic viscera not unfrequently suffer during preg- 191 nancy. Palpitation of the heart is a very common affection, and extremely distressing. It is a disease so well known, that it is needless here to describe it; but it may not be improper to observe, that women themselves sometimes mistake for it a strong pulsation of the arteries, at the upper part of the abdo- men. It may make its attack repeatedly in the course of the day; or only at night, before falling asleep; or at the interval of two or three days; and is very readily excited by the slighest agitation of the mind. It is generally void of danger; but in delicate women, and in those who are disposed to abortion, it sometimes occasions that event; and if long con- tinued, it may excite pulmonic disease in those who are pre- disposed to it. Absolute rest, with antispasmodics, are re- quisite during the paroxysm. Hartshorn, ether, and tinc- ture of opium, may be given, separately or combined. Ro- deric a Castro prescribes a draught of hot water. The attacks are to be prevented by the administration of tonics, such as tincture of muriated iron; and of foetids, such as valerian and asafoetida. Fatigue and exertion must be avoid- ed, and the mind kept tranquil. If the person be plethoric, it is sometimes useful to take away a little blood. The bowels are to be carefully kept open. The diet must be at- tended to ; for it is often produced by a disordered stomach. A tendency to nervous or hysterical diseases is to be pre- vented, in those who are liable to them, by occasional blood- letting, the use of laxatives, and camphor, or foetids. Opiates are only to be given for the immediate relief of urgent symp- toms. § 14. SYNCOPE. Another distressing affection of the heart, attendant on pregnancy, is syncope. This may take place at any period of gestation, but is most frequent in the three first months, or about the time of quickening. It often occurs in those who are otherwise healthy, but it also may occur daily for sometime in those who are weakened by a loose state of the bowels, alternating with costiveness, or by want of sleep oc- 193 casioned by tooth-ach. It may succeed some little exertion, or speedy motion, or exposure to heat; but it may also come on when the person is at perfect rest. The paroxysm is sometimes complete, and of long duration; at other times, the person does not lose her knowledge of what is going on, and soon recovers. A recumbent posture, the admission of cold air, or application of cold water to the face, the use of volatile salt, and the cautious administration of cordials, con- stitute the practice during the attack. Should the fit remain long, we must preserve the heat of the body, otherwise a protracted syncope may end in death. Those ,vho are sub- ject to fainting fits, must avoid fatigue, crowded or warm rooms, fasting, quick motion, and agitation of the mind. Tonics are useful when the system is weak, and the bowels must be regulated. There is a species of syncope, that I have oftener than once found to prove fatal in the early stage of pregnancy, which is dependent, I apprehend, on organic affections of the heart, that viscus being enlarged, or otherwise diseased, though perhaps so slightly as not previously to give rise to any troublesome, far less any pathognomonic symptoms. Although I have met with this fatal termination most fre- quently in the early stage, I have also seen it take place so late as the sixth month of pregnancy. § 15. DYSPNCEA AND COUGH. Sudden attacks of dyspnoea in those who were previously healthy, are generally to be considered as hysterical, and are readily removed by antispasmodics. There is, however, a more obstinate and protracted symptom, not unfrequently connected with pregnancy, namely cough. This may come in paroxysms, which are generally severe, or it may be al- most constant, in which case it is short and teasing. Some- times a viscid fluid is expectorated, but more frequently the cough is dry. During the attack, the head is generally pain- ful, and the woman complains much of the shaking of her body, especially of the belly. All practical writers are 193 agreed with respect to the danger of this disease, for it is ex- tremely apt to induce abortion; and it is worthy of remark, that after the child is expelled, the cough often suddenly ceases. But exposure to cold frequently brings it back; and should there be a predisposition to phthisis, that disease may be thus excited. Blood-letting must be early, atid sometimes repeatedly employed; the bow els kept open; and lozenges, containing opium or hyoscyamiis, must be occasionally used, to allay the cough. A large burgundy pitch plaster, applied betwixt the shoulders, is of service. Should abortion take place, and the cough continue, tonics, such as myrrh and oxyde of zinc, ought to be administered. § 16. HEMOPTYSIS AND II.EMATEMESIS. In some instances, haemoptysis or haematemesis take place in pregnancy, especially in the last months, and these are very dangerous affections. Blood-letting is the remedychiefly to be depended on ; and afterwards purgatives should be given; acids and hyoscyamiis may be employed to allay irritation. If these means do not succeed, the patient dies. Should the hemorrhage take place during labour, or should pains come on prematurely, and the os uteri dilate, as sometimes happens, it will be prudent to accelerate the delivery. § 17. HEAD-ACHE AND CONVULSIONS. Head-ache is a very alarming symptom, when it is severe, constant, and accompanied with symptoms of plethora. If the eye be dull or suffused, and the head giddy, especially when the person stoops or lies down, with a sense of heavi- ness over the eyes, or within the skull, great danger is to be apprehended, particularly if the woman be far advanced in her pregnancy. This is still more the case, if she complain of ringing in the ears, and flashing of fire in the eyes, or in- distinct vision. In such circumstances, she is seized either with apoplexy or epilepsy. These diseases are to be prevent- ed by having immediate recourse to blood-letting and purga- vol. T. c c 194 tives; and the same remedies are useful, if either one or other of these diseases have already taken place. The quan- tity of blood which is to be detracted, must be determined by the severity of the symptoms, the habit of the patient, and the effect of the evacuations; but, generally, moderate evacuation will prevent, whilst very copious depletion is re- quisite to cure these diseases. If the head-achebe accompanied with oedema, the digitalis is a useful addition to the practice. I shall not at present enter more minutely into the treatment of epilepsy. I shall only remark, that the first thing to be done is to detract blood from a vein; next, the bowels are to be immediately opened by a clyster, and then a purgative is to be administered. If the patient is seized with apoplexy, there is seldom any attempt made to expel the child,* and, in my own practice, I have never known that event take place. In epilepsy, on the contrary, if the paroxysm be protracted there is gene- rally an effect produced on the uterus; its mouth opens, and the child may be expelled, if the patient be not early cut off by a fatal coma. Whenever expulsive effects come on, we must conduct the labour according to rules hereafter to be noticed. In some instances, palsy either succeeds an apoplec- tic attack, or follows head-ache and vertigo. This disease docs not commonly go off until delivery have taken place; but it may be prevented from becoming severe, by mild laxatives and light diet; and, after the woman recovers from her la- bour, the disease gradually abates, or yields to appropriate remedies. All head-aches, however, do not forbode these dismal events, for often they proceed from the stomach, and evidently de- pend on costiveness, dyspepsia, or nervous irritation. These are generally periodical, accompanied with a pale visage, they feel more external than the former, and are often con- fined to one side of the head. They are attended with aci- dity in the stomach, eructations, and sometimes considerable giddiness pr slight sickness, with bitter taste in the mouth. * Mr. Wilson's case is an exception to this. Vide Med. Facts, vol. v. p. 96. 195 They are relieved by the regular exhibition of laxatives, by sleep, the moderate use of volatiles, and the application of ether externally. Hysterical convulsions are not uncommon during gestation, and more especially during the first four months. They occur in irritable habits, or in those who are naturally dis- posed to syncope, or who have been exhausted by any pain, depriving them of rest, or by alvine discharges. They are distinguished by the face usually being pale during the at- tack, the countenance is very little distorted, there is no foam issuing from the mouth, the patient for a time lies as in a faint, and then has convulsive motions, or screams and sobs, and the fit generally is terminated by shedding tears. The treatment, in the first instance, consists in administering antispasmodics, particularly opiates and volatile foetids. Af- terwards, the returns are to be prevented by bringing the bowels into a correct state, and keeping them so. The ex- ercise is to be gentle, but taken regularly. The diet mild but nourishing. Sleep is to be procured, if necessary, by opiates; and tonic medicines, with the assistance of ammoniated tinc- ture of valerian, must complete the cure. § 18. TOOTH-ACftE. Tooth-ache not unfrequently attends pregnancy, and, some- times, is a very early symptom of that state. The tooth may be sound or diseased, but in neither case, ought we to extract it, in the early months, if it be possible to avoid the opera- tion. I have known the extraction followed in a few minutes by abortion. Blood-letting frequently gives relief, and, sometimes, a little cold water taken into the mouth abates the pain. In other cases, warm water gives more relief. § 19. SALIVATION. Salivation is, with some women, a mark of pregnancy. It has been supposed that there is a sympathy existing between the pancreas and salivary glands, and that the phlegm re- 196 jected by vomiting proceeded from the former, whilst, in many instances, the latter yielded an increased quantity of viscid saliva. This is a symptom which scarcely demands any medicine, but, when it does, mild laxatives are the most efficacious. § 20. MASTODYNIA. Pain and tension of the mammae frequently attend gesta- tion, and these symptoms are often very distressing. If the woman have formerly had a suppuration of one mamma, that breast is generally most painful, and she is afraid of abscess again forming. In other instances, the pain, being accompa- nied with increased hardness of the breast, produces appre- hension of cancer. These fears are generally groundless; but if suppuration do take place, it is to be treated on general principles. Blood-letting often relieves the uneasy feeling in the breast, which is also mitigated by gentle friction with warm oil. Nature often gives relief, by the secretion of a serous fluid which runs out from the nipple; but if this be much encouraged by suction, Chambon remarks, that the foetus may be injured. ' The discharge is in some instances so great about the seventh month, or later, as to keep the woman very uncomfortable. The diet in this case should be dry. The sudden abatement of the tension, and fulness of the breasts, with a diminution of size, are unfavourable circum- stances, indicating either the death of the child, or a feeble action of the womb. § 21. 03DEMA. In the course of gestation, the feet and legs very generally become oedematous; and sometimes the thighs, and labia pudendi participate in the swelling. The swelling is by no means proportioned always to the size of the womb, for, as has been remarked by Puzos, those who have the womb un- usually distended with water, and those who have twins, have 197 frequently very little oedema of the feet. This disease is partly owing to the pressure of the uterus, but it also seemi to be somewhat connected with the pregnant state, inde- pendent of pressure; for in some instances, the oedema is not confined to the inferior extremities, but affects the whole body. A moderate degree of oedema going off in a recumbent pos- ture is so far from being injurious, that it is occasionally re- marked, that many uneasy feelings are removed by its acces- sion ; but a greater and more universal effusion indicates a dangerous degree of irritation, and may be followed by epi- lepsy. In ordinary cases, no medicine is necessary except aperients; but, when the oedema is extensive or permanent, remaining even after the patient has been for several hours in bed, it may be attended with unpleasant or dangerous effects, such as convulsions; or, it may predispose to puerpe- ral diseases ; we must therefore lessen it by means of those agents which alleviate the other diseases of pregnancy, namely, blood-letting and purgatives. These means are always proper, unless the strength be much reduced; in which case, we only employ the purgatives and cordials prudently, with acetate of potash, or sweet spirit of nitre. Diuretics, generally, are not successful, and many of them, if given liberally, tend to excite abortion. Friction relieves the feel- ing of tension. § 22. ASCITES. Ascites may, like oedema, be excited, in consequence of some condition connected with gestation, or may be inde- pendent of it, arising from some of the ordinary causes of dropsy, especially from a disease of the liver. In the last case, medicine has seldom much effect in palliating or re- moving the disease ; and the woman usually dies, within a week or two after her delivery, whether that have been pre- mature, or delayed till the full time. When ascites is not occasioned by hepatic disease, and appeals for the first time during gestation, it is generally connected with the oedema- tous state above-mentioned, and seldom comes on until the 198 woman has been at least three months pregnant. If it be not attended with other bad symptoms, such as head-ache, feverish- ness, drowsiness, &c. it abates and goes off, a little before, or soon after delivery, which is often premature. I have seen diuretics given very freely in these cases, but most frequently without any benefit. On this account, and also from the danger of these exciting abortion, or premature labour, I am inclined to dissuade from their use, except in urgent cases. Then the mildest ought to be employed, such as cream of tar- tar, juniper tea, acetate of pot-ash, &c. If any of these produce much irritation of the urinary organs, they must be exchanged for others. Purgatives and blood-letting are more useful. Ascites may have existed previously to pregnancy, and the two causes combined, may produce a very great enlargement of the belly. In this case, the uterus may be felt through the teguments, sometimes very much compressed, as if the child lay across. Mild diuretics tend to keep the disease at bay; and if the distension be very great, especially at an early stage, my experience leads me to conclude, that after quick- ening, a great part of the fluid may be drawn off safely, pro- vided, during the operation and afterwards, the abdomen be carefully and uniformly supported by a bandage. It is useful to know this, as the distension is sometimes so great, that life could not go on, without much distress, till the end of gesta- tion. The operation, I think, is more apt to be succeeded by labour, if performed in the last month, than earlier.(«) (z) Instances have occurred, where in cases of ascites combined with pregnancy, the operation of paracentesis has been performed, although this is a practice by no means to be commended. In the eighth Vol. of the Lon- don Med. Facts and Observations, there is a case related by Mr. Simmons, of a pregnant woman with symptoms of ascites being twice tapped, first, in the second month of pregnancy, when fourteen quarts of water were drawn off, and the second time, when five months advanced, when only a few ounces of blood followed the withdrawing of the trocar; at the full time she was delivered of a healthy child, having suffered no inconvenience from the operation. Another case is related in the seventh Vol. of the London Med. and Phys. .lournal, by Dr. Vieusseux, of Geneva, where a woman in the fifth month of pregnancy wai tapped, but it appears that the consequence of this opera- 199 § 23. REDUNDANCE OF LIQUOR AMNII. When the liquor amnii is in too great quantity, much in- convenience is produced, and not unfrequently the child perishes. This disease is known, by the woman being un- usually large at an early period of gestation, for generally by the seventh month, she is as big as she ought to be in the ninth. It is distinguished from ascites, by the motion of the child being felt, though obscurely, by the mother, and the breasts enlarging. Per vaginam we can ascertain, that the uterus contains a substance, which alternately recedes and descends as the finger strikes on the lower part of the womb. This is to be considered as a dropsical affection of the ovum, but the health of the woman seldom suffers so much as in dropsy; the tongue, however, is white, and the urine is di- minished in quantity. The legs are less apt to swell than in a common pregnancy. The distension may, in the advanced stage, prove troublesome. When the quantity of water is greatly increased, the child is seldom kept till the full time, but is generally expelled in the eighth month, or sooner, and the labour is apt to be accompained or succeeded by uterine hemorrhage. In some instances, the child occupies the upper part of the uterus, and the water the under, at least during tion was an abortion, although the patient soon recovered. Both these cases are related by the gentlemen under whose observation they fell, to prove that the paracentesis has been performed, and even the uterus perforated, [which they suppose was the case in both these instances,] without material injury to the patient. In the same work is related a case of a woman, who was tapped no less than five times during pregnancy : at the full period she was, notwithstand- ing, delivered of a fine child, and recovered completely from the puerperal state. These cases prove, how much the system will sometimes suffer with im- punity, but at the same time we must acknowledge, that it is best not to pre- sume too far on the preservative energies of nature. Sometimes pregnancy has been, from gross inaccuracy, mistaken for drop- sy, and the paracentesis been performed with a fatal effect; the patient in one instance fainting, and expiring almost instantaneously. Upon examina- tion after death, it was found that the trocar had not only perforated the uterus, but had also penetrated the foetus! soo labour. Twice in the same woman, in succeeding pregnan- cies, I found the child contained in the upper part of the uterus, and embraced by it as if it were in a cyst, whilst se- veral pints of water lay between it and tfce os uteri. When the water came away, filling some basons, then the child de- scended to the os uteri, but was born dead, with the thighs turned firmly up over the abdomen, and other marks of de- formity. This is a disease of the ovum and not of the mother, un- even the foetus itself is often malformed, or at least blighted. The affection in toto, may be considered as a sp. cies of monstrous conception. Some particular condition ot the parent may, however, in certain cases, occasion it. For in- stance, it may be connected with a syphilitic taint in either the father or mother; or with some less obvious cause im- pairing the action of the womb, but not directly producing a miscarriage; with lunacy or idiotism; or with a state of ge- neral or uterine debility; or with an original imperfection of the ova in the ovarium : for a woman may, without any ap- parent cause, have repeatedly this kind of pregnancy. All of these causes do not operate uniformly to the same extent, but the foetus suffers in proportion to their operation. It is either born very feeble and languid, and is reared with difficulty or it dies almost immediately, or it perishes before labour com- mences ; and this is generally the case when the diseased state exists to any great degree. The period of the child's death is usually marked by a shivering fit, and cessation of motion in utero, at the same time that the breasts become flaccid. Af- terwards irregular pains come on, with or without a watery discharge. Sometimes the woman is sick or feverish for a few days before labour begins. If the liquor amnii be not increased greatly beyond the usual quantity, the woman may go the full time, but, from the distension of the uterus, is apt to have a lingering labour. Tonics, the cold bath, dry diet, with occasional venesec- tion, and the use of laxatives, during pregnancy, may be of service, but frequently fail. Diuretics do no good. A course of mercury conducted prudently, previous to conception, is 201 the only remedy, when we suspect a syphilitic taint. It may be necessary to prescribe it to both parents. When it pro- ceeds from some more latent cause, I think it is useful, for preventing a repetition of the disease, to make the mother nurse, even although her child be dead. Mercury ought also to be tried. When the distension produces much distress, it has been proposed to draw off the water by the os uteri; or this has been done in one case by the common operation of paracen- tesis, the woman surviving, and labour taking place on the twenty-first day.* This practice is, however, generally im- proper, and is seldom requisite, pains usually coming on whenever the symptoms become severe. When the os uteri is considerably dilated by the pains, it may be proper to rup- ture the membranes, as has been advised by Puzos. § 24. WATERY DISCHARGE. Discharges of watery fluid from the vagina arc not unfre- qucnt during pregnancy, and generally depend upon secre- tion from the glands about the cervix uteri. It has been supposed, that in every case they proceeded from this cause, or from the rupture of a lymphatic, or the evacuation of a fluid collected between the chorion and amnion, or the water of a blighted ovum, in a case of twins; for in every instance, where the liquor amnii has been artificially evacuated, labour has taken place. But we can suppose, that the action of ges- tation may, in some women, be so strong, as not to be inter- rupted by a partial evacuation of the liquor amnii. Even granting the water to he collected exterior to the chorion, there must be a strong tendency to excite labour, if the quan- tity discharged be great ;f and if the uterus can resist this, it may also be unaffected by the evacuation of liquor amnii. I have known instances, where after'a fright or exertion, a * Vide case by Noel Desmarais, in Recueil Period. Tom. VI. p. 349. M. Baudelocque gives a memoir on this subject in the same volume. f Vide Dr. Alexander's case, in Med. Comment. Vol. III. p. 187. VOL. I. D D 202 considerable quantity of water has been suddenly discharged, with subsidence of the abdominal tumour, or feeling of slack- ness ; and even irregular pains have taken place, and yet the woman has gone to the full time.* These prove, as far as the nature of the case will admit of proof, that the water has been evacuated. Sometimes, only one discharge has taken place, but oftener the first has been followed by others; and these are often tinged with blood. The aperture seems to heal, if gestation go on ; for during labour, a discharge of water takes place. Much more frequently labour does take place. Even wheu the discharge proceeds only from the vessel op glands about the os uteri, if the woman be not care- ful, a hemorrhage may take place, followed by labour. This is most likely to happen if there have been a copions dis- charge. The practice in these cases, is to confine the patient for some time to bed. An anodyne ought also to be given, and may be repeated occasionally, if she be affected either w ith irregular pain, or nervous irritation; previous venesection often renders this more useful. The bowels are to be kept open. If we suppose the discharge to be from the glands or vessels about the os uteri, we may, with advantage, inject some astringent fluid, such as a solution of sulphate of alu- mine. It sometimes happens, that a large hydatid is lodged be- tween the ovum and the os uteri, and it may be expelled se- veral weeks before parturition. If care be not taken, this may be followed by hemorrhage. * Dr. Pentland relates a very distinct case, where the liquor was, in the third or fourth month, discharged in a fit of coughing. The belly fell, but she still went on to the full time, and had a good labour. Dublin Med. and Phys. Essays, No. I. art. 3.—1 have known a discharge of water take place, at short intervals, for some weeks; and then the funis umbilicalis protruded, without any exertion, or any pains to rupture the membranes, which is a demonstration that the membranes had been previously open, and that the discharge of liquor did not speedily excite labour. 803 § 25. VARICOSE VEINS. Varicose tumours sometimes appear on the legs. They are not dangerous, but are often painful. By pressure, they can be removed ; but I am not sure that it is altogether safe to apply a bandage round the legs, so tight as to prevent their return. It is better, in ordinary cases, to do nothing at all; but where there is much pain, a recumbent posture, and mo- derate pressure, give relief. § 26. MUSCULAR PAIN. From the distension of the abdominal muscles, pain may be produced, either about the extremities of the recti muscles, or the origins of the oblique or transverse muscles. These pains are not dangerous, but give unnecessary alarm if the cause be not known. It is impossible to remove them, but they may be mitigated by anodyne embrocations. If the pain be severe along the edge of the ribs, relief may be obtained by applying round the upper part of the abdomen a narrow band of leather, spread with adhesive plaster. There is another cause of pain, which sometimes affects these muscles, but oftener those about the pelvis and hips. This seems to consist in a diminished power of the muscles, in consequence of the uterine action, and thus the fibres are not capable of the same exertion as formerly. A long walk, or some little fatigue, may produce such an effect, as to render them painful for a long time: or even without any unusual degree of motion, they may ache, and produce the sensation of weariness. These pains have been supposed to be most frequent when the woman has twins, but this is far from being a general rule. They may occasion an apprehension that she is going to miscarry. Rest is the principal remedy; but if they he severe, relief may often be obtained by vene- section. Pain in the side, particularly the right side, is sometimes at an advanced period of gestation, both muscular, and also connected with the state of the bowels, especially of the colon. 204 It is frequently most severe, and may be rendered still more distressing by being combined with violent heartburn, or water brash. It comes on chiefly at night, and instead of being relieved by lying down, is often increased on going to bed. It is usually accompanied with much motion of the child. Venesection sometimes gives relief, but generally more advantage is derived from rubbing with anodyne balsam, attending to the state of the bowels, and regulating the diet. Although the pain be very severe, it seldom brings on labour. § 27. SPASM OF THE URETER. Spasm of the ureter, or some violent nephritic affection, may occur during gestation. The pain is severe, the pulse slow and soft, and the stomach often filled with wind. The symptoms are attended with distressing strangury, and, if not soon removed, may cause premature labour. Decided relief is obtained by giving a saline clyster, and, after its operation, injecting eighty drops of laudanum, mixed with a little starch. A sinapism is to be applied to the loins, and if these means fail, blood must be taken away. § 28. CRAMP. Spasms in the inferior extremities are often very distress- ing. These may come on suddenly, but occasionally, they are preceded by a sense of coldness, and accompanied with a feeling of heat. They are removed by change of posture, and gentle friction. They have, by some, been thought to indicate a wrong presentation of the child, but this opinion is not supported by experience. They proceed from the pres- sure of the uterus on the nerves in the pelvis. § 29. DISTENSION OF THE ABDOMEN. In a first pregnancy, the abdominal muscles generally preserve a greater degree of tension than they do afterwards; and therefore the belly is not so prominent as in succeeding 205 pregnancies. Sometimes the muscles and integuments yield so readily to the uterus, that it falls very much forward, producing a great prominence in the shape, inconvenience from the pressure on the bladder, and pain in the sides, from the increasing weight of the projecting uterus. In such cases, benefit may be derived from supporting the abdomen with a bandage connected with the shoulders. In other in- stances, the muscles and integuments do not yield freely, but the belly is hard and tense; the woman feels shooting pains about the abdomen, and sometimes miscarries. This state is relieved by blood-letting and tepid fomentations. When the skin does not distend freely, and becomes tender and fretted, or when these effects are produced by very great distension, benefit is derived from fomenting with decoction of poppies, and afterwards applying a piece of soft linen, spread very thinly with some emollient ointment. There is sometimes a disposition to distend unequally, so that one side yields more than the other, or even part of one side, or one muscle more than the rest, producing a peculiar shape. This is attended with no inconvenience. § 30. HERNIA. It is very usual for the navel of pregnant women to become prominent, even at an early stage. In some instances, such a change is produced, as to allow the intestine or omentum to protrude, forming an umbilical hernia; or if the woman have been formerly subject to that disease, pregnancy tends to increase it, whilst, on the other hand, the intestines being soon raised up by the ascending uterus, inguinal and femoral hernia are not apt to occur, or are even removed if they for- merly existed. Umbilical hernia ought to be either kept re- duced by a proper bandage, or at least prevented, by due support, from increasing; and during delivery, we must be careful that the intestine be not forcibly protruded, as it might be difficult to replace it. After delivery, a truss must be applied, with spring wings which come round by the side of th© belly. 206 In some cases, during gestation, the fibres of the abdomi- nal muscles separate, so that a ventral hernia is formed. The same circumstance may take place during parturition ; and the laceration is sometimes so large, that afterwards, when- ever the muscles contract, as, for instance, in the act of rising, a quantity of intestine is forced out, forming a hard tumour like a child's head. It is necessary in this, and in all other cases of large hernia, to be careful that compression be applied immediately after delivery, and also during the expulsion of the child. By neglecting this, syncope and uterine hemorrhage have been occasioned. Hcrniee of the bladder should always be reduced in the commencement of labour, for it may interfere with the pro- cess of parturition, or the bladder may be exposed to injury. § 31. DESPONDENCY. It is not uncommon to find women very desponding dur- ing pregnancy, and much alarmed respecting the issue of their confinement. This apprehensive state may be the con- sequence of accidents befalling others in parturition; but not unfrequently it proceeds from a peculiar state of mind, de- pendent on gestation. Some, who at other times enjoy good spirits, become always melancholy during pregnancy, whilst others suffer chiefly during lactation. Little can be done by medicine, except to obviate all cause of disease or uneasiness of the body; the mind is to be cheered and supported by those who have most influence with the patient. §32. RETROVERSION OF UTERUS. Retroversion of the uterus was described by Gregoire and Levret, but was in this country first accurately, explained by Dr. Hunter, in 1754. It is an accident, which is always at- tended with painful, and sometimes fatal consequences, chiefly owing to the effect produced on the bladder. If the pelvis he of the usual size, it may take place at any time during the 207 third and fourth months of pregnancy ;(a) or if the pelvis be large, or the ovum not much distended with water, it may occur in the fifth month. It may also be produced, when the womb is enlarged to a certain degree by disease.1 We recog- nise retrovei'sion of the uterus chiefly by its effects on the blad- der, and also by difliculty in voiding the faeces; for although the patient may be distressed sometimes with tenesmus, she usually passes little at a time. When the retroversion is com- pleted, bearing-down pains may be excited, as if an attempt were made to expel or force down the uterus itself. These are much connected also with the state of the bladder, being most severe when it is distended, and abating when the urine is evacuated. The acute symptoms produced by the distension of the bladder, or the inability to pass the urine freely, first of all call the attention of the woman to the disease; and when we come to examine her, we find a tumour betwixt the rectum and vagina.2 This is formed by the fundus uteri, which is thrown backwards and downwards, whilst the os uteri is directed forward, and sometimes so much upwards, as not to be felt by the finger. This is a disease which we would (a) A suppression of urine from retroversion of the uterus, may arise at other periods, as well as during a state of pregnancy, and generally from the same cause, viz. over-distension of the bladder. Thus, after delivery, the uterus sometimes becomes retroverted, occasioning an entire suppres- sion of urine, and excessive pain; and the same thing, not uncommonly, takes place when the uterus is in a state of disease ; and sometimes at the period of life when the Catamenia usually cease. At this period the uterus is apt to enlarge and grow heavy, without manifesting any other indications of disease ; and in this state more than one instance have occurred of its be- coming retroverted. Di. Merriman says, that the cases of retroversion of the uterus after deli- very, which have fallen under his observation, have principally occurred on the second day after the birth of the child; probably because the degree ol contraction, which the womb has by that time undergone, has reduced it to a size the most fit to suffer such a displacement. It has happened after easy labours, and notwithstanding the patients had passed their urine once or twice. The second day after delivery has not, however, been invariably the period of this occurrence ; for a case occurred to Dr. Merriman, where the patient was attacked with a suppression of urine from this cause on the ninth diy after delivery. " Vide Merriman's Dessertation on Retroversion of the womb," p.p. 19,20. 208 think cannot be mistaken, and yet it is sometimes difficult to distinguish it; for in extra-uterine pregnancy, it has hap- pened, that the symptoms have been nearly the same with those of retroversion ;* and tumour of the ovarium has some- times produced similar effects. Perhaps the diagnosis can- not, in every case, be accurately made, but this is of less im- mediate importance, as the indication in such instances must be the same, namely, to draw off the urine, and procure stools. Retroversion may take place slowly, and it has been said that its progress could be ascertained from day to day ;3 but in most instances, and in every case that I have seen, it has taken place pretty quickly ; and occasionally the woman has been sensible at the time, of a tumbling or motion within the pelvis. Sometimes the urine dribbles away involuntarily, or can be passed in small quantity, especially during the com- mencement of the disease; but often, within a few hours, it becomes almost completely obstructed, with pains about the loins, tenderness in the lower belly when it is touched, and a severe bearing-down sensation. The great danger proceeds from the distension4 of the bladder, which either hursts5 or inflames,6 and an opening takes place, in consequence of gan- grene; or the bladder adheres to the abdominal parietes, its coats becoming thickened and diseased.7 If the urine cannot be drawn off, of which I have never yet met with an instance, death is preceded by abdominal pain, vomiting, hiccup, and sometimes convulsions. These effects are chiefly produced by mistaking the nature of the complaint. Their duration is variablc.| Inflammation and gangrene of the vagina and external parts have also been produced. If the disease do not prove rapidly fatal, so much urine escaping as to prevent a speedy termination, it occasionally happens, that hectic fever is produced. The pulse becomes frequent, the body * Vide Mr. Giffard's case, in Phil. Trans. Vol. XXXVI. p. 435, and Mr. White's very instructive case, in Med. Comment. Vol. XX. p. 254. ■j Dr. Perfect's patient died thus on the sixth day. Cases in Midwifery, VoL 1 .p. 394. 209 wastes, and purulent urine is voided ;8 or the person may become adematous, and the disease pass for dropsy ;° occa- sionally the water is not quite obstructed, but it is voided with difficulty for a week or two, and then the symptoms become nv»re acute, and forcing pains are excited. . Our first object is to relieve the bladder, by introducing a catheter,10 which may be slightly curved, the coneavitybcing directed to the sacrum; or we may employ an elastic catheter; but in general, the common instrument succeeds. If it do not pass easily, we may derive advantage from introducing the finger into the vagina, and endeavouring to depress the os uteri, or press back the vaginal tumour.11 If the catheter cannot be introduced, we have been advised to tap the blad- der;12 but this, fortunately, is never requisite. We must not be deceived with regard to the state of the bladder, by observing that the woman is able to pass a small quantity of water, for it may, nevertheless, be much distended. We must examine the belly, and attend to the sensation pro- duced by pressure on the hypogastric region. Even although the catheter have been employed, only part of the urine may have been drawn off, particularly if the complete evacuation has not been assisted by moderate pressure over the bladder. It has happened, that only so much has been taken away as to give a little relief, and alter the position of the uterus so much as to lessen the pressure on the orifice of the bladder. In this case, on getting up, a great quantity of urine has flowed spontaneously, and the womb immediately returned to its proper state. The urine being evacuated, and the most immediate source of alarm being thus removed, we must, in the next place, pro- cure a stool, by means of a clyster; detract blood, if there be fever or restlessness; and give an anodyne injection, if there be strong bearing-down efforts. This is, in general, all that is requisite ; and I wish particularly to inculcate the necessity of directing the chief attention to the bladder, which ought to be emptied at least morning and evening. By this plan, we generally find, that the uterus resumes its proper situation in the course of a short time, perhaps in forty-eight vox. I. K Fi 210 hours ;13 and the retroversion is seldom continued for more than a week, unless the displacement has been very complete. The precise time, however, required for the ascent of the womb will be determined cseteris paribus, by the degree to which it has been retroverted, and the attention which is paid to the bladder. If the fundus be very low, the ascent may be tedious; but I consider myself as warranted from experience to say, that in every moderate degree of retrover- sion, in every recent case, it is sufficient to empty the blad- der regularly without making any attempt to push up the womb. But if the uterine tumour be very low, and near the perineum, it may be necessary, and certainly it is allowable, to endeavour to replace the womb. This is also proper, if there be much irritation excited by the state of the womb, and which does not give way to the use of the catheter, and of anodyne clysters. I fear, however, that these efforts shall seldom succeed, and that more harm than good is generally done by them. It may be said, that although the immediate danger be done away by the regular use of the catheter, yet the womb may remain forever in its malposition, and give rise to great difliculty in labour, or to the same event as in extra-uterine pregnancy. I can only reply, that in almost every instance where the bladder has been regularly emptied, the case has done well; and I do believe, that in those where the uterus did not rise spontaneously, very little good could have been done by mechanical efforts. The attempt to replace the uterus is to be made by intro- ducing two fingers of one hand into the rectum, and a suffi- cient number of those of the other hand, or the whole hand itself, into the vagina. The uterine tumour is then to be pressed up slowly, firmly, and steadily ; and this may some- times be assisted by elevating the breech of the woman. Forcible and violent attempts are, however, to be strongly reprobated; they give great pain, and may even excite abor- tion, inflammation, or convulsions. They can only be justifi- ed on the principle of preventing a great danger. Now we know that the chief risk proceeds from the distension of the bladder; if, therefore, it can be emptied, the danger is usually 211 at an end. When the retroversion ceases, the uterus usually resumes completely its proper situation; but it sometimes happens, especially if the vagina have been much relaxed, that when the retroversion is removed, the uterus is found very low, forming a prolapsus, which continues for some time. It requires, chiefly, attention to the urine and stools; for it may occupy the pelvis fully, and pretty firmly; and almost the whole fcetus can be felt by the finger through the uterus. When the uterus ascends, occasionally a little blood is dis- charged ;* but abortion does not take place unless much in- jury has been sustained. Thus the woman has miscarried quickly after the bladder had burst, as in Mr. Lynn's patient; or when inflammation had taken place, as in the cases related by Drs. Bell and Ross. When this happens, the uterus rises indeed, but the patient is cut off by peritoneal inflammation,14 followed by vomiting of dark coloured stuff. Abortion will generally take place, if the liquor amnii have been discharged. That the uterus does generally rise spontaneously, if the urine be regularly evacuated, is a fact of which I am fully convinced from my own experience, as well as from the ob- servations of others. But it is nevertheless possible for it to continue in a certain degree of malposition even to the end of gestation.1* In this case, the uterus cannot, indeed, at last be said exactly to be retroverted; for it has enlarged so much, that it occupies nearly as much of the abdomen as usual; but it has enlarged in a peculiar way, the os uteri being still directed to the symphysis pubis, or even perhaps raised above it. In such a case, which is exceedingly rare, the labour will be very tedious and severe. The os uteri will be very long of being felt, and will he first perceived at the pubis.(fr) We * M. Roger's case, in Act. Havn. Tom. H. art. 17. (6) The first case of this kind that has been accurately stated as such, is to be met with in a small, but judicious work, by Dr. H. S. Jackson, entitled, "Cautions to Women respecting the State of Pregnancy. London, 1798," and was attended by several of the most respectable practitioners of Lon- don ; the next case which has been made public, was that which fell under the immediate notice of Dr. Merriman, and by him minutely detailed in the London Medical and Physical Jounial, for 1806; and afterwards published In a distinct and separate work, entitled, " A dissertation on Retroversion »f 212 are indebted to Dr. Merriman for an explanation of this fact, and likewise for the observation that it is possible for the termination to be similar to that of extra-uterine pregnancy, the Womb, including some Observations on Extra-uterine Gestation. Lon- don, 1810." It will be found by consulting Dr. Merri man's paper and work above al- luded to, that he considers, and with some appearance of probability, that certain of those cases of difficult labour, which by Deventer have been re- ferred to his supposed obliquity of the uterus, and others, which have by different authors, been considered as cases of extra-uterine conception, were in fact, cases of retroversions ol the uterus continuing, in a certain degree, until the full period of utero-gestation, and then impeding delivery. He likewise observes, that it is not unlikely, that some of those cases which are found in Smellie's and other collections, where the os uteri is described as grown together and impervious, were actually retroversions of the uterus. In these cases, incisions have been frequently made within the vagina, into the Uterus. [Vide Sabatier Medicine Operatoire, Vol. I. p. 310.] There is also another class of cases, of which many are recorded by writers on Midwifery, which may probably owe their orign and cause to a retroverted state of the uterus. We here allude to those cases of extra-ute- rine foetuses discharged per anum, or through an ulcerated opening in the vagina, after having remained for many years in the abdomen of the mother. [Vide Mainwaring, in 2d vol. of Transactions of the Society for the Im- provement of Med. and Chirurg. Knowledge, and Coleman in 2d vol. of Med. and Phys. Journal, and Giffard, in Eclectic Repertory, vol. 1. p. 346, & seq.] When foetuses have been found in the cavity of the abdomen entirely dis- engaged from the uterus, it is probable that a rupture of this viscus, or an ulcerated opening through its parietes, in consequence of its deranged situa- tion, had permitted the escape of the foetus after it had ceased to five, and not that the conception had advanced to maturity, in a part apparently so illy adapted to such a purpose. By this explanation, we may solve what has hitherto been to many a diffi- culty in the history of these cases, it has, for instance, been observed in every case of foetus carried, as it was supposed, in the abdomen beyond the period of nine months, that near the usual time of parturition, the pains of labour have regularly come on, and strong efforts appear to have been made by the uterus, as if for the expulsion of the child. . Now, as it has been well observed, it is difficult to assign any reasons for these contractions of the uterus, if the fortus has no connection with that organ ; but if the foetus is contained in the partially retroverted uterus, or in any of the appendages of the uterus, the occurrence of these contractions might naturally be expected. Vide Dr. Merriman's paper and work above referred to. 213 namely, by suppuration. A case of this kind, well marked in all respects, except suppression of urine, is related by Dr. Barnum* as an instance of extra-uterine gestation. In the fifth month, after some imprudence, the patient had pain ac- companied with a discharge of water and some blood, a mark that the ovum was in the uterus. She got relief at this time; but next month, (Nov.) she had a return of pain, and the os uteri was felt directed to the pubis, and the fundus to the sacrum. All attempts to reduce it failed, as they generally do, suppuration took place, and foetal bones were discharged by the anus. She died in March. In order to prevent retroversion, we must understand its cause, which most frequently, if not always consists in dis- tension of the bladder. The os uteri is thus elevated, and the fundus falls in the same proportion backward. Now in the unimpregnated state, the uterus is not sufficiently large to remain retroverted ; and after the fourth month of preg- nancy, the uterus is too heavy to be much raised by the blad- der, and too large to fall into the pelvis. If, however, the pelvis be very wide, and the uterus have consequently been longer, than usual of rising, it may be retroverted at a later period. It would appear, that agitation, or violent exer- tion,16 may cause this state to take place more readily than would otherwise happen; hut whether concussions, or other circumstances, can produce retroversion, without some pre- vious distension of the bladder, is not positively proved, though some facts favour the supposition. The same woman has been known to have the uterus retro- verted in two successive pregnancies.! § 33. ANTIVERSION. The uterus is also said to be sometimes antiverted, that is, the fundus is thrown forward, so as to compress the neck of • Vide New York Med. Rep. V. 40. I Vide case by Dr. Senter, in Trans, of Phys at Philadelphia, p. 130. Both times it was reduced by the hand. 214 the bladder, and its mouth is turned to the sacrum.17 Of this accident I have never seen an instance, and, from the nature of the case, it must be very rare. The urine should be evacuated, and the fundus raised up. § 34. RUPTURE OF UTERUS. Rupture of the gravid uterus may take place at any period of gestation. The moment of the accident is generally mark- ed by severe pain, occasionally by vomiting, and frequently by a tendency to syncope, which, in some instances, con- tinues for a length of time to be the most prominent symp- tom.* The pain sometimes resembles labour, but more fre- quently colic, and its duration is variable. In some cases, hemorrhage takes place from the vagina, but the greatest quantity of the blood18 flows into the abdomen. At the time of the accident, and for a little thereafter, the child is felt to struggle violently. Then the motion ceases, the woman feels a weight in the belly, and, if the pregnancy be far ad- vanced, the members of the child can be traced through the abdominal parietes.19 The tumour of the belly generally28 lessens, and milk is secreted, indicating the death of the child. If hemorrhage, or peritoneal inflammation, do not quickly carry off the patient, we find, that at the end of some time, occasionally of the ninth month of gestation, pains like those of labour come on, which either gradually go off, and the child is retained for many years, f being inclosed in a kind of cyst; or inflammation and abscess take place, and the child is discharged piece-meal.21 ■ In some instances, it would appear, that the ovum may be expelled entire into the abdomen ; and in that case, it is pos- sible for the child to live for some time, and even to grow, although out of the uterus. When this happens, its motions * Vide Dr. Underwood's case, in Lond. Med. Journ. Vol. VII. p. 321. f In Dr. Percival's case, the foetus was retained for 22 years, and then dis- charged by the rectum. 215 are felt more freely and acutely than formerly. As the os uteri opens a little after the expulsion, and a sanguineous dis- charge takes place, the woman has sometimes been supposed to miscarry. If she survives, the womb slowly decreases in size, and returns to the unimpregnated state,23 which will as- sist materially in the diagnosis, between this and extra-ute- rine pregnancy existing from the first. The menses return, and though the belly does not subside completely, yet the person continues tolerably well, unless inflammation come on. She may even bear children before the extra-uterine foitus be got rid of.* If the case is to prove fatal, the pulse be- comes quick and small, the belly painful, the strength sinks, and sometimes continued vomiting ushers in dissolution.23 Rupture of the uterus may be the consequence of mental agitation,! but in most cases it is owing to external vio- lence.24^ Three modes of treatment present themselves. To leave the case to nature; to deliver per vias naturales ; and to per- form the cesarean operation. To dilate the os uteri forcibly, and thus extract the child, is a proposal so rash and hazard- ous, that I know none in the present day who would adopt it. I question if the woman would live till the delivery were accomplished. The csesarean operation is safer, and in every • Vide Journ. de Med. Tom. V. p. 422. f Dr. Percival's patient attributed her accident to a fright; Dr. Underwood's referred her's to mental agitation. $ The uterus may be ruptured by a variety of causes. 1. By external violence, as by blows, falls, pressure, &c. 2. By rude attempts to turn the child, and especially, after the waters are discharged. This has often happened. 3. By convulsions. 4. By the inordinate action of the uterus, constituting what is termed spon- taneous rupture. This last is, by much, the most common cause. But when rupture is thus produced, we may suspect that an improper treatment has been pursued. We can, undoubtedly, by copious bleeding, and the subse- quent administration of opium, so far overcome the resistance, and mitigate the violence of the pains, as to prevent its occurrence. The same remedies will, moreover, obviate, in most instances, rupture from convulsions; and should never be neglected as precautionary means, where there are any ap- prehensions of the accident from turning the child. C. 216 respect preferable; but we cannot yet, from experience, de- termine its advantages, and certainly it ought not to be per- formed, unless we can thereby save the child. The third proposal, therefore, to leave the case to nature, like an extra- uterine pregnancy, is most likely to be successful, more espe- cially when the rupture happens in the early months of ges- tation. We find, from the result of cases, that the woman has the best chance of recovery, if we are satisfied with ob- viating symptoms, and removing inflammation in the first instance; and supporting the strength of the patient through the progress of the disease, should it not prove rapidly fatal; enjoining rest, giving mild diet, and favouring the expulsion of the bones, by poultices and fomentations, and, if necessary, by enlarging the abscess if it point externally.* * This negative sort of practice has, undoubtedly, met with many very re- spectable advocates. There are, at the present day, several eminent prac- titioners, besides Mr. Burns, who strenuously recommend it. Notwith- standing, however, the weight of authority in its favour, I cannot believe it to be right. The powers of nature seem to me to be totally incompetent in such cases. By prompt delivery only we can hope to do good. This, then, we should always attempt. In some cases the forceps may be used, but they are few, as the rupture commonly takes place before labour is suffi- ciently advanced to admit of their application. We, therefore, turn the child, and bring it away by the feet. Delivery in this manner has been more than once effected, and the woman preserved, even where the child had escaped through the rupture of the uterus into the abdominal cavity. I al- lude now, more particularly, to the case recorded by Dr. Douglass, and to one which occurred to Dr. J. Hamilton. To these, I may also add, as show- ing, at least, the practicability of delivery under such circumstances, a case, related by my friend Dr. James, in the Medical Repository of New York. Were the rupture to happen in the earliest stage of labour, I should nevertheless not be deterred from adopting this practice. I would forcibly, but not violently, dilate the uterus. It does not strike me that the attempt would be " rash and hazardous." We often in other emergencies do it with advantage, as in labour attended with hemorrhage or convulsions. Why may it not also be done in lacerated uterus ? But if, by deformity of the pelvis, or contraction of the uterus, (the child being in the cavity of the abdomen) or indeed from any other circumstances, there exists insuperable impediments to delivery per vias naturales, 1 would, without hesitation, resort to the cesarean section. In deliberating on the ex- pediency of adopting this dreadful alternative, we should constantly bear in recollection that we are not without examples of the success of the ope- ration. 817 § 35. ABORTION AND TREATMENT OF PREGNANT WOMEN. The usual period of utero-gestation is nine months, but the foetus may be expelled much earlier. If the expulsion take place within three months of the natural term, the woman is said to have a premature labour; if before that time, she is said to miscarry, or have an abortion. The process of abor- tion consists of two parts, detachment and expulsion; but these do not always bear a uniform relation to each other in their degree. The first is productive of hemorrhage, the second of pain; for the one is attended with rupture of ves- sels, the other with contraction of the muscular fibres. The first may exist without being followed by the second, but the second always increases, and ultimately completes the first. The symptoms then of abortion, must be those pro- duced by separation of the ovum, and contraction of the uterus. To these, which are essential, may be added others more accidental, induced by them, and varying according to the constitution and habits of the patient. The ovum may be thrown off at different stages of its growth; and the symptoms, even at the same period, vary in duration and degree. The process of gestation may be checked, even before the fcetus or vesicular part of the ovum has descended into the uterus, and when the decidua only is formed. In this case, which ocelli's within three weeks after impregnation, the symptoms are much the same with those of menorrhagia. There is always a considerable, and often Two cases with favourable results are related, one by Dr. Barlow, and the other by Dr. J. Hamilton. In the latter case, the bones of the pelvis were so mashed by the wheel of a cart as altogether to prevent dehvery by the na- tural passages. On opening the abdomen, the child was found in the cavity, and the uterus considerably lacerated. But notwithstanding the extent and severity of the injury, the woman entirely recovered. Let it not, however, be understood that I am at all sanguine as regards the two remedies which 1 have proposed. I am, on the contrary, persuaded that in most instances, they will wholly fad. But what else can be done in these tremendous cases ? To leave them to nature, " like an extra-uterine concep- t,on," would be, either to consign the woman to immediate death, or what re -still worse, to death from protracted and torturing illness. C. VOL. J. V V 218 a copious discharge of blood, which coagulates or forms clots. This is accompanied with marks of uterine irritation, such as pain in the back and loins, frequently spasmodic affections of the bowels, and occasionally a slight febrile state of the system. In plethoric habits, and when abortion proceeds from over-action, or hemorrhagic action of the uterine ves- sels, the fever is idiopathic, and precedes the discharge. In other circumstances it is either absent, or, when present; it is symptomatic and still more inconsiderable, arising merely from pain or irritation. As the primary vessels are very small, and are soon displaced, they cannot be detected in the discharge. Nothing but coagulum can be perceived; and this, as in other cases of uterine hemorrhage, is often so firm, and the globules and lymph so disposed, as to give it, more especially if it have been retained for some time about the uterus or vagina, a streaked or fibrous appearance, which sometimes gives rise to a supposition, that it is an organized substance. The discharge does not cease when the primary vessels are destroyed, but generally continues until the small vesicle passes out of the fallopian tube. Then it stops, and an oozing of serous fluid finishes the process. The only interruption to the discharge in this case of abor- tion, proceeds from the formation of clots, which, however, are soon displaced. Women, if plethoric, sometimes suffer considerably from the profusion of the discharge; but, in ge- neral, they soon recover. If the vesicle have descended into the uterus, the symptoms are somewhat different. We have an attempt in the uterus to contract, which formerly was not necessary; we have pains more or less regular in the back and hypogastric region; we have more disturbance of the abdominal viscera, particularly the stomach. The discharge is copious, and small bits of fibrous substance can often be observed. Sometimes the vesi- cle may be detected in the first discharge of blood, and will be found to be streaked over with pale vessels, giving it an appearance as if it had been slightly macerated. When all the contents are expelled, a bloody discharge continues for a few hours, and is then succeeded by a serous fluid. At this 219 lime, and in later abortion, if the symptoms take place gra- dually, we may sometimes observe a gelatinous matter to come away before the hemorrhage appears. If to# uterus contain more vascular and organized matter, as in the beginning of the third month, the vesicle never escapes first; but we have for some time a discharge of blood, accompanied or succeeded by uterine pain. Then the inferior part or short stalk of the ovum may be expelled, gorged with blood, and afterwards the upper part equally injured. Some- times the whole comes away at once and entire; but this is rare. As considerable contraction is now required in the uterus, the pains are pretty severe. The derangement of the stomach is also greater than formerly, giving rise to sickness or faintness, which is a natural contrivance for abating the hemorrhage. When the membranes come to occupy more of the uterus, and a still greater difference exists betwixt the placenta and decidua, we have again a change of the process; we have more bearing-down pain, and greater regularity in its attack; we have a more rapid discharge, owing to the greater size of the vessels; but there is not always more blood lost now than at an earlier period, for coagula form readily from temporary fits of faintness, and other causes, and interrupt the flow until new and increased contraction displaces them. Often the membranes give way, and the foetus escapes with the liquor amnii, whilst the rest of the ovum is retained for some hours or even days,* when it is expelled with coagulated blood se- parating and confounding its different parts or layers. At other times the foetal and maternal portions separate, and the first is expelled before the second, forming a very beautiful preparation. In some rare instances we find the whole ovum expelled entire, and in high preservation. After the expul- sion, the hemorrhage goes off, and is succeeded by a dis- charge, somewhat resembling the lochia. In cases of twins, after one child is expelled, either alone or with its secundines, the discharge sometimes stops, and the * In all cases the placenta is retained much longer after the expulsion of the child in abortion, than in labour at the full time. 220 woman continues pretty well for some hours, or even for a day or two, when a repetition of the process takes place, and if she has been using any exertion, there is generally a pretty rapid and profuse discharge. This is one reason, amongst many others, for confining women to bed for several days after abortion. There is frequently, for a longer or shorter time before the commencement of abortion, pain and irregular action in the neighbouring parts, which give warning of its approach, before either discharge or contraction take place ;* unless when it proceeds from violence, in which case the discharge may instantly appear. This is the period at which we can most effectually interfere for the prevention of abortion. I need not be particular in adding, that we are not to confound these symptoms with the more chronic ailments which accom- pany pregnancy. A great diversity obtains in different instances with regard to the symptoms and duration of abortion. In some cases the pains are \ery severe and long continued ; in others, short and trifling; nor is the degree of pain always a correct index of the force of contraction. Sometimes the hemorrhage is profusef and alarming; at other times, although circum- stances may not be apparently very different, it is moderate or inconsiderable. Often the sympathetic effects on the stomach and bowels are scarcely productive of inconvenience, whilst in a greater number of instances they are very prominent symptoms. I may only add, that, cceteris paribus, we shall find, that the farther the pregnancy is advanced beyond the third month, and the nearer it approaches to the end of the sixth, the less chance is there of abortion being accompanied, but the great- er of its being succeeded, by nervous affection. As there is a diversity in the symptoms, so is there also • In some cases, shooting pains and tension are felt in the breasts before abortion, and the patient is feverish. | Those who are plethoric generally lose much blood, unless the contrac- tion have been brisk. In some cases six or seven pounds of blood have been lost in a few hours. in the duration of abortion; for, wiiilst a few hours in many, and not above three days in the majority of cases, is sufficient to complete the process, we find other instances in which it is threatened for a long time, and a number of weeks elapse before the expulsion takes place. In some cases the child appears to be dead for a consider- able time before the symptoms which accompany expulsion occur. But in a great majority of cases it is living, when the first signs of abortion are perceived, and in some in- stances is born alive. The signs by which we judge that the child in utero is dead, are the sudden cessation of the morn- ing sickness, or of any other sympathetic symptom which may have been present. The breasts become flaccid. If milk had been formerly secreted, it sometimes disappears, but in other instances the contrary happens, and no evident secretion takes place until the action of gestation, or at least the life of the child be lost, In almost every case, however, the breasts will be found to have lost their firmness. If the pregnancy had advanced beyond the period of quickening, the motion of the child will be lost, and a feeling of heaviness will be felt about the pelvis. When all these signs are ob- served, and when they are followed by discharge, and espe- cially when this is attended with pain, there can be no doubt that expulsion will take place, and it would be improper to prevent it. We are not, however, to conclude that the child is dead, merely because it does not move; and when abortion is threatened before the term of quickening, this sign cannot enter into our consideration. When the ovum perishes at a very early period, and is not immediately discharged, we find that the sympathetic signs of pregnancy disappear, and not unfrequently a serous or milky fluid comes from the nipples. The woman feels lan- guid and hot at night, or has fits of sickness, or hysterical symptoms; a discharge of foetid dark coloured fluid takes place from the vagina, and is often mixed with particles like snuff. This continues till all the remains of the ovum have come away, and then the health and spirits are restored. If at a more advanced period, the ovum remains after the 222 child dies, it is converted either into a mole or hydatid ; and this may also happen even at a very early stage of pregnancy. These cases have already been considered. It is generally most prudent to obviate symptoms, and wait until the os uteri open and pains come on. Then we are to be directed by ex- isting circumstances. Whether the ovum become putrid, or undergo a change into hydatids, it is reasonable to expect that the vessels of the uterus being no longer employed in the growth of the foetus should diminish, and become in the first case merely sufficient to nourish the uterus ; and, in the se- cond, to supply the necessities of the substance attached to the inner surface of the womb; for there is a communication between them, and a discharge of blood attends the expulsion of either a mole or hydatid; whereas, on the other hand, if the ovum has perished completely and become putrid, the discharge is rather a foetid sanies than red blood. Abortion may \ery properly be divided into accidental and habitual. The exciting causes of the first class may, in ge- neral, be easily detected; those giving rise to the second are often more obscure; and, without great attention, the woman will go on to miscarry, until either sterility, or some fatal dis- ease, be induced. In many cases there can be no peculiar pre-disposing cause of abortion ; as, for instance, when it is produced by blows, rupture of the membranes, or accidental separation of the de- cidua: but when it occurs without any very perceptible excit- ing cause, it is allowable to infer, that some pre-disposing state exists; and this frequently consists in an imperfect mode of uterine action, induced by age, former miscarriages, and other causes. It is well known, that women can only hear children until a certain age; after which, the uterus is no longer capable of performing the action of gestation, or of performing it properly. Now, it is observable, that this in- capability or imperfection takes place sooner in those who are advanced in life before they marry, than in those who have married and begun to bear children earlier. Thus we find, that a woman who marries at forty, shall be very apt to miscarry; whereas, had she married at thirty, she might have S23 borne children when older than forty; from which it may be inferred, that the organs of generation lose their power of act- ing properly sooner, if not employed, than in the connubial state. The same cause which tends to induce abortion at a certain age in those who have remained until that time sin- gle, will also, at a period somewhat later, induce it in those who have been younger married; for in them we find, that, after bearing several children, it is not uncommon to con- clude with an abortion; or, sometimes after this incomplete action, the uterus, in a considerable time, recruits, as it were, and the woman carries a child to the full time, after which she ceases to conceive. In the next place, 1 mention that one abortion paves the way for another; because, setting other circumstances aside, it give the uterus a tendency to stop its action of gestation at an early period after conception, and therefore it is difficult to make a woman go to the full time, after she has miscarried frequently. This fact has also been explained upon the prin- ciple of repeated abortion weakening the uterus*, and this certainly may have some influence. The renewed operation of those causes which formerly induced abortion, may like- wise account in many cases for its repetition. But I am also inclined to attribute the recurrence, sometimes, to habit alone, by which I understand that tendency which a part has to re- peat or continue those modes of acting which it has frequent- ly performed, as we see in many diseases of the stomach and windpipe; spasmodic affections of these and other organs, being apt to return at the same hour, for a long time. With regard to the uterus, one remarkable instance is related by Schulzius, of a woman, who, in spite of every remedy, mis- carried twenty-three times at the third month. In this, and similar cases,' slighter causes applied at the period when abortion formerly happened, will be sufficient to induce it, than would be required at another time. We also find that an excessive or indiscriminate use of ve- * Perhanc vero consuetudinem nihil aliud intelligo, quam pravam vasorum uteri laxitatem et inde provenientem humorum stagnationem, ex aborticndi labore sxpius repetito inductam. Hoffmax, Tom. iii. p. 180. 224 nery, either destroys the power of the organs of generation altogether, making the woman barren, or it disposes to abor- tion, by enfeebling these organs. Some slight change of structure in part of the uterus, by influencing its actions, may, if it do not prevent conception, interfere with the process of gestation, and produce prema- ture expulsion. If, however, the part affected be very small, and near the os uteri, it is possible for pregnancy to go on to the full time. Indeed, it generally does go on, and the la- bour, as may be foreseen, will be very tedious; but the opera- tion of cutting the indurated os uteri, which has been pro- posed, is seldom necessary. I have known one instance, in which a very considerable part of the uterus, I may say al- most the whole of it, was found, after delivery, to be extreme- ly hard, and nearly ossified; but this state could not have existed before impregnation took place, for I cannot conceive that so great a proportion of the uterus should have been originally diseased, and yet that conception, and its conse- quent actions, should take place ; but there is less difficulty in supposing, that, during the enlarging of the uterus, the vessels deposited osseous or cartilaginous matter, instead* of muscular fibres. A general weakness of the system, which must affect the actions of the uterus, in common with those of other organs, is likewise to be considered as giving rise to abortion, though not so frequently as was at one time supposed. A local weakness of the uterus sometimes exists when the general system is not very feeble; or when the constitution is delicate, the uterus may be weaker in proportion than other organs. In this case, it cannot perform its function with the necessary activity and perfection, but is very apt, after a time, to flag. We cannot operate with medicines di- rectly upon the womb, for the purpose of strengthening it, hut must act on it by invigorating the general system, and at- tending to all the other functions. Sea-bathing is of great service; and after impregnation, every exciting cause of abortion must be guarded against. Women of this descrip- tion are generally pale, of a weakly, flabby habit, and sub- 225 ject to jirregular, often to copious menstruation, or fluor al- bus. When they conceive, the cold bath, light digestible food, open bowels, and free air, should be enjoined; and if any uneasy sensation be felt about the uterus or back, or the pulse throb, a little blood should be slowly taken away, and the woman keep her room for some days. Bleeding prevents the womb from being oppressed, and it is as necessary to at- tend to this, as it is to prevent the stomach from being load- ed in a dyspeptic patient. But, on the other hand, were we to bleed copiously, we might injure the action of the uterus, and destroy the child. It has been supposed that abortion might arise from a rigi- dity of the uterus, which prevented its distension. But the uterus does not distend like a dead part,-upon which pres- sure is applied, but it grows, and therefore I apprehend that an effect is here considered as a primary cause. The uterus is not only affected by the general conditions of the system, more especially with regard to sensibility, and the state of the blood vessels; but it likewise sympathizes with the principal organs, and may undergo changes in con- sequence of alterations in their state. Thus we often find that loss of tone, or diminished action of the stomach, produces amenorrhoea; and it may also on the same principle induce abortion ; on the other hand, the action of the uterus may influence that of other viscera, as we see in pulmonary consumption, which is sometimes suspend- ed in its progress during pregnancy; or, if there be any dis- position in an organ to disease, frequent abortion, partly by sympathy betwixt the uterus and that organ, and partly by the weakness which it induces, and the general injury which it does to the system at large, may excite the irregular or mor- bid action of the organ so disposed. As the action of the uterus is increased during pregnancy, it must require more nervous energy; but the size of the nerves of the uterus is not increased in proportion to the ac- tion ; we must therefore depend for the increased supply upon the trunks, or larger portion of the nervous substance, from which they arise, for we well know that the quantity of energy VOL. I. 6 G 226 expended in an organ, does not depend upon the size of the nerve in its substance, but on the trunk which furnishes it. Whenever action is increased in an organ, it must either perish, or the larger nerve must send the branches more energy ; for the branches themselves cannot form it, their ex- tremities being only intended for expending it; from which it follows, that in pregnancy there must be more energy sent to the uterus, and less to some other part. This is the case with all organs whose action is increased, other parts being deprived in proportion as they are supplied, except when irritation raises general action above the natural degree ; the consequence of which is, that the power is not sufficient for the action, which becomes irregular, and the system is exhausted, as we see in febrile conditions. There being increased action of the uterus in gestation, re- quiring an increased quantity of energy to support it, we find that the system is put pro tempore into an artificial state, and obliged either to form more energy, which cannot be so easily done, or to spend less in some other part. Thus the function of nutrition, or the action by which organic matter is deposit- ed, in room of that which is absorbed, often yields, or is les- sened, and the person becomes emaciated, or the stomach has its action diminished, or the bowels, producing costiveness and inflation. If no part give way, and no more energy than usual be formed, gestation cannot go on, or goes on imper- fectly. Hence some women have abortion* induced by being too vigorous: that is to say, all the organs persist in keeping up their action in perfection and complete degree. A tendency to abortion also results from a contrary cause, from organs yielding too readily, allowing the uterus to act too easily. In this state it is as liable to go wrong, as the general system is when it is at the highest degree of action, compatible with health; the most trifling cause deranges it. Thus, sometimes, the intestines yield too readily, and become almost torpid, so that a stool can with difficulty be procured. Here costiveness is not a cause of abortion, though it may be blamed. In like manner, the muscular system may yield and become enfeebled; and in this instance debility is accused as 227 the cause of abortion although it be, indeed, only an effect of too much energy being destined for the uterus. In this case, the woman is always weaker during menstruation and gesta- tion than at other times. If the neighbouring parts do not accommodate themselves to the changes in the direction of energy, and act in concert with the uterus, their action becomes irregular, and conse- quently painful. In this case, the uterus may have its just degree of power and action ; but other parts may not he able to act so well under the change of circumstances. This is chiefly the case in early gestation, for, by time, the parts come to act better. It often gives rise to unnecessary alarm, being mistaken for a tendency to abortion; but the symptoms are different. The pain is felt chiefly at night, a time at which weakened parts always suffer most; it returns pretty regular- ly for several week, but the uterus continues to enlarge, the breasts to distend, and all things are as they ought to be, if we except the presence of the pain. This may be alleviated by bleeding, and sometimes by anodynes; but can only be cured by time, and avoiding, by means of rest and care, any additional injury to parts already irregular and ticklish in the performance of their actions. If this be neglected, they will re-act on the uterus at last, and impede its function. It is therefore highly necessary, especially in those disposed to abortion, to pay attention to pains about the back, loins, or pubis; and to insist upon rest, open bowels, and detracting blood, if the state of the vascular system indicate evacuation. Even although the different organs, both near and remote, may have accommodated themselves to the changes in the uterine action, in the commencement of gestation, the proper balance may yet be lost at a subsequent period; and this is most apt to take place about the end of the third, or begin- ning of the fourth month, before the uterus rises out of the pelvis: and hence a greater number of abortions take place at that time than at any other stage of pregnancy. There is from that time, to the period of quickening, a greater sus- ceptibility in the uterus to have its action interrupted, than either before or afterwards: which points out the necessity of 228 redoubling our vigilance in watching against the operation of any of the causes giving rise to abortion from the tenth to the sixteenth week. If the action of gestation go on under restraint, as, for in- stance, by a change of position in the uterus, or by its pro- lapsing too low in the vagina, it is very apt to be accompanied by uneasy feelings, for, whenever any action is constrained, sensation is produced. The woman feels irregular, and pretty sharp pains in the region of the uterus, and from sympathetic irritation both the bladder and rectum may he affected, and occasionally a difficulty is felt in making water, by which a suspicion is raised that retroversion is taking place. Some- times the cervical vessels in these circumstances yield a little blood, as if abortion were going to happen; hut by keeping the patient at rest, and attending to the state of the rectum and bladder, no harm is done; and when the uterus rises out of the pelvis, no farther uneasiness is felt. Occasionally a pretty considerable discharge may take place under these cir- cumstances, if the vascular system be full, or the vessels about the cervix large. But, by care, gestation will go on; for dis- charge alone does not indicate that abortion must necessarily happen. It, indeed, often causes abortion, and is almost al- ways an attendant upon it; but we form our judgment, not from this symptom alone, but also from the state of the mus- cular fibres, and the vitality of the child. Retroversion of the uterus likewise constrains very much its action, and may give rise to abortion, though in a greater number of instances, by care, gestation will go on, and the uterus gradually ascend. The bowels are to be kept open, and the urine gradually evacuated. Sometimes in irritable or hysterical habits, the process of gestation produces a considerable degree of disturbance in the actions of the abdominal viscera, particularly the sto- mach ; exciting frequent and distressing retching or vomiting, which may continue for a week or two, and sometimes is so violent, as to invert the peristaltic motion of the intestines near the stomach, in which case feculent matter, and, in some instances, lumbrici are vomited. 22a This affection is often accompanied by an unsettled state of mind, which adds greatly to the distress. We sometimes, in these circumstances, have painful attempts made by the mus- cles to force the uterus downward, and these are occasionally attended by a very slight discharge of blood. We have, however, no regular uterine pain; and, if we are careful of our patient, abortion is rarely produced. The best practice is to take away a little blood at first, to keep the bowels open, to lessen the tendency to vomit, by ap- plying leeches, or an opium plaster, or a small blister, to the region of the stomach, and to allay pain by doses of hyoscy- amiis or opium, conjoined with carminatives. When the mind is much affected, or the head painful, it is proper to shave the head, and wash it frequently with cold vinegar, or apply leeches to the temples; at the same time we keep the patient very quiet, and have recourse to a soothing manage- ment. The uterus being a large vascular organ, is obedient to the laws of vascular action, whilst the ovum is more influenced by those regulating new-formed parts; with this difference, how- ever, that new-formed parts or tumours are united firmly to the part from which they grow by all kind of vessels, and ge- nerally by fibrous or cellular substance, whilst the ovum is connected to the uterus only by very tender and fragile arte- ries and veins. If, therefore, more blood be sent to the ma- ternal part of the ovum, than it can easily receive and circu- late and act under, rupture of the vessels will take place, and an extravasation and consequent separation be produced; or, even when no rupture is occasioned, the action of the ovum may be so oppressed and disordered, as to unfit it for conti- nuing the process of gestation. There must, therefore, be a perfect correspondence betwixt the uterus and the ovum, not only in growth and vascularity, but in every other circum- stance connected with their functions. Even when they do correspond, if the uterus be plethoric, the ovum must also be full of blood, and rupture is very apt to take place. This is a frequent cause of abortion, more especially in those who menstruate copiously. On the other 23U hand, when the uterus is deficient in vascularity, which often happens in those who menstruate sparingly or painfully, or who have the menses pretty abundant, but watery, the child generally dies before the seventh month, and is expelled. The process is prematurely and imperfectly finished. The existence of plethora is to be considered as a very fre- quent cause of abortion, and requires most particular atten- tion. It more especially obtains in the young and vigorous, or in those who live luxuriously, and sleep in soft warm beds. It renders the uterus too easily supplied with blood : the in- crease is not made in the regular degree, corresponding to the gradual increase of action, and augmentation of size; but it is, if I may use the expression, forced on the uterus, which is thus made for a time to act strongly and rapidly. This ac- tion is sometimes so great, that the person feels weight in the region of the uterus, and shooting pains about the pelvis; but, in other instances, the vessels suddenly give way, with- out previous warning, and the blood bursts forth at the os uteri. This cause is especially apt to operate in those who are newly married, and who are of a salacious disposition, as the action of the uterus is thus much increased, and the existence of plethora rendered doubly dangerous. In these cases, when- ever the menses have become obstructed, all causes tending to increase the circulation must be avoided, and often a tem- porary separation from the husband is indispensable. Often do we find that slight exertion, within a fortnight after the menses stop, will produce a speedy and violent eruption of blood, which continues until the vessels are fully unloaded, and until all that part of the process of forming an ovum which has been effected, be undone. Abortion necessarily implies separation of the ovum, which may be produced mechanically, or by spontaneous rupture of the vessels, or by an affection of the muscular fibres. It un- avoidably requires, for its accomplishment, contraction of those fibres which formerly were in a dormant state. A natural and necessary effect of this contraction is to developc the cervix uteri. This, when gestation goes on regularly, i 238 great hemorrhage may be sustained, and yet the strength soon recover. But if there be any disposition in a particular organ to disease, abortion may make it active, and thus, at a remote period, carry off the patient. Miscarriages, if fre- quently repeated, are also very apt to injure the health, and break up the constitution. When abortion is threatened, the process is very apt to go on to completion; and it is only by interposing, before the ex- pulsive efforts are begun, that we can be successful in prevent- ing it; for whenever the muscular contraction is universally established, marked by regular pains, and attempts to distend the cervix and os uteri, nothing, I believe, can check the pro- cess. As this is often the case before we are called, or, as in many instances abortion depends on the action of gestation being stopped by causes, whose action could not be ascertain- ed until the effect be produced, we shall frequently fail in preventing expulsion. This is greatly owing to our not being called until abor- tion, that is to say, the expulsive process has begun; where- as, had we been applied to upon the first unusual feeling, it might have been prevented. What I wish then particularly to inculcate is, that no time be lost in giving notice of any ground of alarm, and that the most prompt measures be had recourse to in the very beginning; for, when universal uterine contraction has commenced, then all that we can do is to con- duct the patient safely through a confinement, which the power of medicine cannot prevent. The case of threatened abortion, in which we most fre- quently succeed, is that arising from slipping of the foot, or from causes exciting a temporary over-action of the vessels producing a slight separation; because here the hemorrhage immediately gives alarm, and we are called before the action of gestation be much affected. Could we impress upon our patients the necessity of equal attention to other preceding symptoms and circumstances, we might succeed in many cases where we fail from a delay, occasioned by their not un- derstanding that an expulsion can only be prevented, by in- terfering before that process begins : for when sensible sign^ 239 of contraction appear, the mischief has proceeded too far to be checked. Prompt and decided means used upon the first approach of symptoms indicating a hazardous state of the uterus, or on the earliest appearance of hemorrhage may, pro- vided the child be still alive, be attended with success. In considering the treatment, I shall first of all notice the most likely method of preventing abortion in those who are subject to it; next, the best means of checking it, when it is immediately threatened; and, lastly, the proper method of conducting the woman through it, when it cannot be avoided. The means to be followed in preventing what may be cal- led habitual miscarriage, must depend on the cause supposed to give rise to it. It will, therefore, be necessaiy to attend to the history of former abortions; to the usual habitudes and constitution of the woman ; and to her condition when she be- comes pregnant. In many instances a plethoric disposition, indicated by a pretty full habit, and copious menstruation, will be found to give rise to it. In these cases, we shall find it of advantage to restrict the patient almost entirely to a vegetable diet, and, at the same time, make her use considerable and regular ex- ercise. The sleep should be abridged in quantity, and taken, not on a bed of down, but on a firm mattress, at the same time that we prevent the accumulation of too much heat about the body. The bowels ought to be kept open, or rather loose, which may be effected by drinking Cheltenham water, or taking some other laxative. We must not, however, carry this plan too far, nor make a sudden revolution in the con- stitution, as this may be productive of permanent mischief, and occasion the diseases which proceed from a broken habit. Whenever the strength is diminished, the appetite impaired, or any other bad effect is produced, we have gone too great length. There is, in plethoric habits, a weakness of many, if not all of the functions; but this is not to be cured by tonics, but by continued and very gradually increased exercise, laxatives, and light diet, consisting chiefly of vegetables. This plan, J240 however, must not be carried to an imprudent length, nor established too suddenly; but regard is to be had to the pre- vious habits. It is a general rule, that exercise should not be carried the length of fatigue, and that it should be taken, if possible, in the country; whilst late hours, and many of the modes of fashionable life, must be departed from. We may also derive such considerable advantage from conjoining with this plan, the shower bath or sea-bathing, that they ought not to be omitted. There is, I believe, no remedy more powerful in preventing abortion than the cold bath, and the best time for using it is in the morning. By means of this, conjoined with attention to the vascular system, and prudent conduct on the part of the patient, I suppose that nine-tenths of those who are subject to abortion, may go on to the full time. If the shower-bath be employed, we must begin with a small quantity of water; and, in some instances, may at first add so much warm water as shall make it just feel cold, hut not to give too great a shock. If the cold bath cause head-ache, this may often be prevented by premising one or two doses of physic. After conception, the exercise must be taken with circum- spection : hut the diet must still be sparing, and the use of the cold bath continued. If the pulse be at any time full, or inclined to throb, or if the patient be of a vigorous habit, a little blood should be taken away at a very early period. In some cases where the action is great, we must bleed al- most immediately after the suppression of the menses. It is not necessary to bleed copiously ; it is much better to take away only a few ounces, and repeat the evacuation when re- quired, and we should manage so as to avoid fainting. The cold bath should be conjoined, and we may derive advantage by using the digitalis,* so as slightly to affect the pulse, keeping it at or below its natural frequency, and to diminish * The acetite of lead has been recommended'by the ingenious and justly celebrated Dr. Rush of Philadelphia, in doses of from one to three grains, given three times a-day. Of this practice I cannot speak from my own ex- perience : but Dr. Rush informs me, that in his hands it has been attended with great success. 241 its throbbing. But it is not requisite to be given to the de- gree employed in some other complaints; and, if it be pushed to an imprudent length, the child may suffer. Half a grain may be given, twice or thrice a-day. It may be continued for two days, and then omitted for a day; and in this way it may be continued till the danger is past. In those cases where the digitalis produces feebleness, it is evidently im- proper to continue it regularly. Indeed, when this effect takes place, its farther exhibition is unnecessary. It is also improper where it ads powerfully on the kidneys. By at- tending to these cautions, it may, in some cases requiring it, be continued with occasional omissions of a day or two, even for some weeks, but it is very seldom necessary to persist in it above a fortnight at most. Injecting cold water into the vagina, twice or thrice a day, has often a good effect, at the same time that we continue the shower-bath every morning. When there is much aching pain in the back, it is of service to apply cl important question to be answered. In those cases where the patient has been allow- ed to lose a great deal of blood frequently and suddenly, when the strength is gone, the pulse scarcely to be felt, the extremities cold, the lips and tongue without blood, and the eye ghastly, shall we venture to deliver the woman ? Shall we by plugging, endeavour to prevent farther loss, and by nourishment and care recruit the strength; or empty the uterus, and then endeavour to restore the loss ? We have only a choice of two dangers. The situation of the patient is most perilous, and I have in practice weighed the argu- ment with that attention which the awful circumstances of the case required. I think myself justified in saying, that we give both mother and child the best chance of surviving by a cautious delivery. For in these cases the uterus is al- most toipid, it possesses no tonic contraction ;f the very con- tinuance of the ovum within it is more than it can bear, and on the most favourable supposition, it would require many days before it could be brought into a state capable of con- tracting. The general system is completely exhausted, and * In those cases where the placenta presents, few practitioners would think of trusting to the evacuation of the hquor amnii j they woidd deliver. If then dehvery be considered as safe and proper in one species of flooding, it cannot be dangerous in the other; and whenever interference in the way of operation is necessary, the security afforded by the introduction of the hand will much more than compensate for any additional pain. But even in this respect, the two operations are httle different, if properly performed. f The use of the plug cannot here certainly prevent the farther loss of blood, for the uterus affords no resistance, the hemorrhage continues, and after death large coagula will be found within the womb. 293 cannot support its condition long. I have never known a woman live twenty-four hours in these circumstances. On the other hand, I grant, that it is possible the woman may die in the act of delivery, or very soon after it; but if she can be supported for two days, we may have hopes of recovery. By a very slow and cautious delivery, and by endeavouring |o excite the action of the uterus, so as to pre- vent discharge afterwards, we not only remove the irritation of the distended womb, but we likewise take away a recepta- cle of blood. During the contraction of the uterus, the blood in its sinuses will be thrown into the system, and tend to support it. Part, no doubt, will escape; but by keeping the hand in the uterus, by supporting the abdomen with a com- press, and exciting the uterine action by cold applications to the belly, we may prevent a great loss. When to these considerations we add the additional chance which the child has for life, our practice, I apprehend, will, in this very haz- ardous case, be decided. When the pulse becomes firmer and fuller upon the contraction of the uterus, the risk from debility is diminished. A full dose of laudanum ought to be given previous to delivery. The remarks upon the subsequent management of the pa- tient, I shall reserve until I consider the treatment of flood- ing, after delivery. At one time it was supposed, that the placenta was, in every instance, attached originally to the fundus uteri, and that it could only be found presenting in consequence of having been loosened and falling down. This accident was supposed to retard the birth of the child, by stopping up the passage, and also was considered as dangerous on account of the flood- ing which attended it. On this account Deventer endeavour- ed to accelerate the delivery by tearing the placenta, or rup- turing the membranes when they could be found. This was a dangerous practice, and very few survived when it was em- ployed. Mr. Giffard and M. Levret* were among the first * Je m'engage a prouver lmo. que le placenta s'implante-quelquefoissiii la circonference de I'orifice de la matrice; c'est-a-dire, sur celui qui du col 293 who established it as a rule that the placenta did not fall down, but was from the first implanted over the os uteri: and the latter gentleman published a very concise and accurate view of the treatment to be pursued. We know, that during the eighth month of gestation, very considerable changes take place about the cervix uteri. It is completely developed and expanded; and in the ninth month, very little distance intervenes betwixt the ovum and the lips of the os uteri. These changes cannot easily take place without a rupture of some of the connecting vessels, for either the placenta does not adapt itself to the changes in the shape of the cervix; or, which happens more frequently, some slight mechanical cause, or action of the fibres about the os uteri, produces a rupture. This rupture may doubtless take place at any period of pregnancy,* but it is much more frequent in the end of the eighth and beginning of the ninth month, than at any other time. But whether the separation happens in the seventh, eighth, or ninth month, the consequent hemorrhage is always profuse, and the effects most alarming. The quantity, but especially the rapidity of the discharge, very frequently pro- duce a tendency to faint, or even complete syncope, during which the hemorrhage ceases, and the woman may continue for several days without experiencing a renewal of it. In some instances she is able to sustain many and repeated at- tacks, which may take place daily for some weeks. These, however, it is evident, cannot be very severe, and the strength must originally have been great. In other instances, the woman never gets the better of the first attack. It indeed va joindre I'interieur de ce viscere, & non sur cehu qui regarde de la vagin. 2do. Qu'en ce cas la perte de sang est inevitable dans les dernier tems de la grossesse. Et 3tio. Qu'il n'y a pas de voye plus sure pour remcdier a cet accident urgent que de fair l'accouchement force"—L'art des Accouchemens, p. 343. * In some cases, hemorrhage has taken place so early as the third month. By proper means this has been stopped, and the patient has continued Well for some months, when the flooding has returned, and the placenta been dis- covered to present. 294 diminishes, but does not altogether leave her, and a slight exertion renews it in its former violence. But whether the patient suffer much or little in the first attack—whether she be feeble or robust, the practice must be prompt, and the most solemn call is made upon the practitioner for activity. The momenTthat a discharge of blood takes places, he ought to ascertain by careful examination the precise nature of the case, and must take instant steps for checking it, if nature have not already accomplished that event. If the os uteri be firm and close in a first attack, we ought to use the plug, which will restrain the hemorrhage, and in- sure the present safety of the patient. If this practice have been immediately followed, she shall in general soon recover, and the length of time for which she shall remain free from a second attack, will depend very much upon the care which is taken of her; but sooner or later the attack must and will return. If the uterus have been injured in its action by the first attack, this will generally be attended with very slight dull pains, and we shall feel the os uteri more open and Iaxer than usual; but if the first and second discharges have been promptly checked, it may be later before these effects be per- ceived ; hut the moment that they are produced, we ought to deliver, and it should even be a rule, that where they are not likdy soon to take place, and the discharge has been profuse and rapid; and'produced those effects on the system which I have already pointed out, as the consequence of dangerous hemorrhage, we must not delay until pains begin to open the os uteri. Fortunately, we are not often obliged to interfere thus early; for by careful management, and the use of the plug, we can secure our patient. Although I have said that we may wait safely until the os uteri begins to open, and asserted, that no woman can die from mere hemorrhage, before the state of the os uteri admit of delivery, I must yet add, on this important subject, that this state docs not consist merely in dilatation, for it may be very little dilated, but in dilatibility;(g) we may safely deli- Qr) TR"«gt>y, a respectable surgeon of Norwich in England, is entitled, as • ve beheve, to the credit of first promulgating this distinction, which is of 295 ver whenever the hand can be introduced without much force. A forcible introduction of the hand on the first attack of he- morrhage, wrould, in many cases, be attended with the greatest danger, and in almost every case is improper and unnecessary. I have never yet seen an instance, where deli- very was required during the first paroxysm, if the proper treatment was followed. Whether it may be required in a second or third attack, or even later, must depend upon the quantity and rapidity of the discharge, its effects and the strength of the woman. But whenever we find the os uteri soften, and in any degree more open than in its usual state, and it admits the finger to be introduced easily within it, we may deliver safely; and if the hemorrhage be continuing, ought not to delay. This state will generally be found ac- companied with obscure pains; but we attend less to the state of pains, than of discharge, in determining on delivery. The pains gradually increase for a certain period, and then go off. During their continuance, the os uteri dilates more; but if the hemorrhage have been, or continues to be considerable, we must not wait until the os uteri be much dilated, as we thus reduce the woman to great danger, and diminish the chance of her recovery. A prudent practitioner will not, on the one hand, violently open up the os uteri at an early pe- riod, but will use the plug, until the os uteri becomes soft and dilatable; and if the hemorrhage^be not considerable, he will even, if the state of the patient allow him, wait until slight pains have appeared, or the os uteri begun sensibly to open great importance to be attended to in practice; his words are, "We should be as much influenced (as respects the period of introducing the harid) by the os uteri being in a state capable of dilatation without violence, as by its being really open; when this is the case, therefore, if the woman's situation demand speedy assistance, we sliould not hesitate to attempt delivery." His Essay on this subject, was published in the year 1777, and is in every respect a valuable work, rendered more so by tiie number of interesting cases ap- pended to it. It has been republished in this city, and is highly worthy of the perusal of every Student and Practitioner of Midwifery. Its title is " An Essay on the Uterine Hemorrhage, which precedes the delivery of the full grown Foetus: illustrated with cases by Edward Uigby, member of the Cor* poration of Surgeons in London." 296 without them; for he will recollect, that the more violence that is done to the os uteri, the greater is the risk of bad symptoms supervening. It is an error into which some have fallen, who look upon debility from discharge, as the only barrier to recovery. Violent delivery may produce inflam- mation, or a very troublesome fever, On the other hand, he will not allow his* patient to lose much blood or have many att^dts; he will deliver her immediately, for he knows that whenever this is necessai'y it is easy, the os uteri yielding to his cautious endeavours. But v ery frequently we are not called until the patient has had one or two attacks, and been reduced to great danger. We find her with feeble pulse, ghastly countenance, fre- quently vomiting, and occasionally complaining of slight grind- ing pains. On examination, the vagina is so filled with clot- ted blood which adheres so firmly by the lymph to the uterus, that at first we find some difficulty in discovering the os uteri. We cannot here hesitate a moment what course to follow. If the patient is to be saved, it is by delivery. The os uteri will be in part dilated; it will easily be fully opened. We per- haps find an edge of the placenta projecting into the vagina, perhaps the centre of the placenta presenting or protruding like a cup into the vagina; but in those cases, the rule is the same. We pass by the placenta to the membranes, rupture them,* and turn the child, delivering according to the direc- tions which I have already given. It may be supposed, that as the treatment is so nearly the same, it is not material that we distinguish whether the pla- centa or membranes present. But it is convenient to make a distinction, because in those cases where the placenta does not present, it is possible, in certain circumstances, to cure the flooding, and carry the patient to the full time; and in those , cases, which are indeed the most numerous, where this cannot be done, we always look to uterine contraction as a very great * assistance, and expect that where that is greatest, the dan- * This is much safer for the child than pushing the hand through the pla- centa: and it is equally advantageous for the mother, and easy to the operator. 297 ger will be least. But when the placenta presents, we have no hope of conducting the woman safely to the full time. We have no ground to look to contraction or labour pains as a mean of safety ; for, on the contrary, every effort to dilate the os uteri separates still more the placenta, and increases the he- morrhage.* The very circumstance which in some other cases would save the patient, will here in general, increase the danger. I say in general, for there are doubtless examples where the patient has by labour, been safely and without as- sistance delivered of the child, when part of the placenta has presented. Nay, there have been instances where the pla- centa has been expelled first, and the child after it.f These examples are to be met with in collections of cases by practi- cal writers ; and some solitary instances are likewise to be found in different journals. It would be much to be lament- ed if these should ever appear without having at the same time a most solemn warning sent along with them to the ac- coucheur, to pay no attention to them in his practice.:}: I am convinced that they may do inexpressible mischief by afford- ing argument for delay, and excusing the practitioner to himself for procrastination. There is scarcely any malady so very dreadful as not to afford some examples of a cure effected by the powers of nature alone; but ought we thence to tamper with the safety of those whose lives are committed to our charge ? Ought we to neglect the early and vigorous use of an approved remedy, because the patient has not in every instance perished from the negligence of the attendant ? It is highly proper to publish the case of a patient who, from hernia, has had an anus formed at his groin, because it adds to our stock of knowledge. But what should we think of a * The greatest number of profuse or alarming hemorrhagies proceed from the presentation of the placenta, or the implantation of its margin over the os uteri; and consequently, the greatest number of cases requiring dehvery are of this kind. f Even in those cases where the placenta is expelled first, the flooding may recur, and the woman die, if she be not assisted. Vide La Motte. Obs. ccxxxviii, and cexxxix. * Most of those who have met with such cases, do not seem to count much upon them. vol. i. q,ci 298 surgeon who should put such a case into the hands of a young man, without, at the same time, saying, " Sir, if such a case ever happen in your practice, either you or your patient will be very much to blame." I do not mean from this to say, that we are to blame, in every instance, the accoucheur who has attended a case where the placenta has presented, and the patient been delivered by nature; far from it, for by the use of the plug, he may have restrained the hemorrhage, pains may have come on, /md the child, descending, may have carried the plug before it: or w hen he was called to his patient, he may have found her already in labour, and the process going on so well and so safely, that all interference would have been injudicious. But these instances are not to be converted into general rules, nor allowed to furnish any pretext for procrastination. They happen very seldom, and never ought to be related to a young man without an express intimation that he is not to neglect delivery, when it is re- quired, upon any pretence whatsoever. § 37. FALSE PAINS. Many women are subject, in the end of gestation, to pains about the back or bowels, somewhat resembling those of la- bour, but which, in reality, are not connected with it. These, therefore, are called false pains. They sometimes only pre- cede labour a few hours; but in many cases, they come on several days, or even some weeks, before the end of pregnan- cy, and may be very frequently repeated, especially during the night, depriving the woman of sleep. They are often con- fined altogether to the belly, shifting their place, and being very irregular both in their attacks and continuance. In some cases they affect the side, particularly the right side, in the region of the liver, and are exceedingly severe, especially in the ev ening; they are accompanied with acidity or w ater- brash, or retching, and generally the child is at that time very restless. These pains may doubtless occur in any habit, but they chiefly harass those who are addicted to the use of cordials. On other occasions, the false pains occupy chiefly 299 the back or hips or upper part of the thighs. They even some- times resemble still more nearly parturient pains, in being at- tended with an involuntary effort on the part of the abdominal muscles, to press down, so as to make the woman suppose that she is about to be delivered; and this is occasionally accom- panied with tenesmus, or with protrusion of the bladder from the vagina, very like the membranes of the ovum. In other cases, they are attended with a discharge of watery fluid from the vagina. False pains may be occasioned by many causes: the most frequent are flatulence ; a spasmodic state of the bowels, resembling slight colic; or irritation, connected with cos- tiveness or diarrhoea; or nephritic affections, often accom- panied with strangury. A sudden motion of the back, or un- usual degree of fatigue, may cause a remitting pain in the back and loins : or getting suddenly out of bed when warm, and placing the feet on the cold floor, may have the same effect. A slight degree of lumbago may also resemble the parturient pains. Agitation of mind, or a febrile state of the body, or some irritation in the neighbourhood of the ute- rus, or some unusual motion of the child, may produce an uneasy sensation in the uterus; and sometimes this is ac- companied by a discharge of watery fluid from the vagina. False pains may often be distinguished by their situation; as for instance, when they affect the bowels or kidneys ; by their shifting their situation ; by their duration; by their ir- regularities ; and by the symptoms with which they are at- tended. But the best criterion is, that they seldom affect the os uteri, that part not being dilated during their con- tinuance. It is necessary however to observe, that a dilated state of the os uteri does not always prove that the pains are those of labour ; for it may be found prematurely dilated, to a slight degree, before the proper term of labour, without any pain. In this case, if the pains proceed from affections of the bowels, no effect is produced during the pain, in ren- dering the os uteri tense, or making it larger. On the other hand, it sometimes happens, that the fibres about the os uteri are prematurely irritated ; and this state may be accompanied with pain, and with a perceptible change in the os uteri J p 300 v \ during a pain. This is a very ambiguous case; but we may \ J be assisted in our judgment, by discovering, that the term (\j of utero-gestation is not completed, that the os uteri is hard or thick, and the pains irregular. In all such cases, it is best to proceed on the supposition, that the woman is not ac- tually in labour; for by letting her alone, she most likely will have a continuance of pain, terminating, it is true, in labour, but the process will be tedious and fatiguing; whereas, by suspending the action by an opiate, and if necessary by vene- section, the woman may go on for some time longer, and shall at all events have an easier delivery. When the false pains are accompanied with a febrile state, or are very distressing during the night, it will be proper to detract blood, and afterwards give an anodyne. In all other cases, it is generally sufficient to keep the woman in a state of rest, open the bowels by means of a clyster, if there be no diarrhoea, and afterwards give an opiate to be succeeded by a laxative. Rubbing with anodyne balsam is also useful. Shivering and tremor occur in some cases, in the end of pregnancy; and as they also occasionally precede labour, they often give rise to an unfounded expectation, that delivery is approaching. They appear to be connected sometimes with the state of the stomach, or alimentary canal; in other instances with some change in the os uteri itself, which, even without pain, may be so far opened or relaxed as to allow the finger very easily to touch the child's head through the membranes. It is usually in the evening, or through the night, that the shivering is felt; and it is occasionally pretty severe, and may be several times repeated. Nothing, how- ever, is required, except a little warm gruel, or a moderate dose of laudanum, which is always effectual. NOTES. BOOK I. CHAP. II. NOTE 1, Page 12.—Dr. Denman mentions an instance, where the pa. tient, in three succeeding pregnancies, was progressively worse, and did not, until the lapse of eight years, recover from the lameness produced by the third dehvery. Introd. Vol. I. p. 16. NOTE 2, p. 13.—In one case, where the symphysis was divided, the pa- tient was able to walk on the 15th day.—In Dr. Smollet's case, although in the 8th month of gestation, the bones were found to rise above each other, yet the woman recovered in two months after dehvery. Smellie, Vol. II. coll. 1, n. i. c. 2. NOTE 3, p. 13.—As an illustration of tliis disease, I shall relate the out- lines of a case mentioned by Louis, in the Memoirs of the Royal Academy of Surgery. A woman in the 2d month of her pregnancy, after pressing in a drawer with her foot, felt a considerable pain at the lower part of the bel- ly» greatly increased by every change of posture; and along with this she complained of strangury. She was bled, and purged, and kept at rest, by which means, especially by the last, she grew better. But in the two latter months of pregnancy, the symptoms were renewed, so that presently she could neither walk, nor even turn in bed, without great pain; but her greatest suffering was caused by raising the legs to pull on her stockings, as then the bones were more powerfully acted on. A slight degree of hectic fever now appeared. Her dehvery was accomplished easily; but on the evening of the 3rd day, when straining at stool, after having received a clyster, the pain, which had troubled her httle since her labour, returned with as much severity as ever. On the 5th day the pulse was very weak and frequent, she sweated profusely, and had a wildness in her countenance, with symptoms of approaching delirium. In the afternoon the pulse became full and tense, with vertigo and throbbing of the arteries of the head. The pain at the symphysis was excruciating, and although she was fomented and bled seven times, she obtained no relief. On the 8th day the pain abated, but diffused itself over the rest of the pelvis, particularly affecting the left hip and the sacrum. On the 11th day she died. On opening the body, there was found a separation of the bones at the pubis, but the capsule was entire, and much distended. It contained about an ounce and a half of matter. Whether the timeous evacuation of this matter might have saved the patient, is a question 302 worth our consideration. I am disposed to answer it in the affirmative, from observing, that wherever the patient has recovered in such circumstances, it has uniformly happened, that a discharge of matter has taken place. NOTE 4, p. 14.—Dr. Laurence shewed Dr. Smellie a pelvis, where all the bones were separated to the extent of an inch. NOTE 5, p. 14.—In a case related by De la Malle, the pain did not ap- pear till the 14th day after dehvery, and was felt first in the groin. The pa- tient was unable to move the leg, and had acute fever, which proved fatal. The sacrum was found separated, three hues from the ilium. In the operation of dividing the pubis in a parturient woman, it was found that one side yielded more than the other, and consequently that side would suffer most at the sacrum. Baudelocque L'Art, &c. section 2063. NOTE 6, p 14.—Dr. Smellie relates an instance, where, during labour, the woman felt violent pain at the right sacro-iliac symphysis. On the 5th day this pain was extremely severe, and attended with acute fever; but the symptoms were abated by blood-letting, and a clyster, and fomentations, which produced a copious perspiration. She was not able to walk for five or six months without crutches, but was restored to the use of the limb, by means of the cold bath. Coll. 1. n. i. c. 1. CHAP. VI. NOTE 1, p. 30.—It is not necessary to give examples of every degree of deformity; but it will be useful to select some specimens of the different kinds. The slighter degrees do not require to be particularized.- I shall first of all give the dimensions of a dried pelvis, so contracted, as to prevent a child at the full time from passing without assistance. From the pubis to the sacrum, it measures three inches; from the acetabulum to the sacrum, on the right side, two and a half inches; on the left, two inches and seven- eighths ; from the brim above the foramen thyroideum, to the opposite sa- croiliac junction, five inches; from the same part of the brim on one side, to the same on the opposite, three inches and a half; transverse diameter, four inches and seven-eighths; from the arch of the pubis to the hollow of the sacrum, five inches; from one tuberosity of the ischium to the other, four inches and a half; from one spine to another, four inches and a half; the arch of the pubis is natural. The distance from the face of the third lumbar vertebra, to the spine of the ilium on both sides, is six inches. These di- mensions may be compared with those of the well-formed pelvis. The sym- physis pubis has the cartilage in the inside, projecting like a spine, wliich, added to the smallness of the pelvis when recent. The linea ilio-pectinea also, on the left side, is for the length of two inches as sharp as a knife; and from these two causes, the cervix uteri and bladder were torn in labour. NOTE 2, p. 30.—In a pelvis of this kind, which I shall describe, the ver- tebrx and sacrum lean much to the left side. The line from the promontory of the sacrum to the part of the pubis opposite it, is barely an inch and a half; but an oblique line drawn to the symphysis, which is to the right of the pro- montory, is near two inches. From the promontory to the side of the brim 303 at the ihum on the left side, is two inches and three-tenths; on the right side, three inches and four-tenths. On the left side, from the lateral part of the sacrum to the acetabulum, is nine-tenths of an inch; on the right side, fully two inches. Now in tliis pelvis, when the soft parts are added, we shall find that an oval body may pass on the right side, whose long diameter is three inches and a half, and whose short diameter is barely two inches. in a pelvis with a semicircular brim, whose short diameter, at the middle and each side, is one inch and a half, an oval could pass when the soft parte are added, whose long diameter is about two inches and a quarter; and the short one about one inch and a quarter. NOTE 3, p. 31.—In a well-formed pelvis, a line drawn transversely along the brim, and in contact with the sacrum, either touches at its two extremi- ties, the sacro-Uiac junctions or the hnea ilio-pectinea, about half an inch before them; but in a very deformed pelvis, such a line will touch the brim, at, or even before the acetabula. In a well-formed pelvis, a line drawn from the middle of the linea ilio-pectinea on one side, to the same spot on the op- postde side, is about an inch, or an inch and a half distant from the sacrum. But in a deformed pelvis, this hne would either pass through the sacrum, or altogether behind it. NOTE 4, p. 31.—The following are the dimensions of a pelvis of this kind, which I select as a specimen. From the spinous process of the ihum on one side to the other, is eight inches and three-fourths. From the lumbar ver- tebrae to the spinous process of the ihum on the right side, six inches; on the left side, one inch and seven-eighths. From the spinous process of the ihum back to its ridge, two inches and a half. From the symphysis pubis to the sacrum, one inch and three-fourths. From the right acetabulum to the sacrum, six-tenths of an inch; from the left, seven-eighths of an inch. From the brim above the foramen thyroideum to the same point on the opposite side, seven-eighths of an inch. From the same part of the brim to the oppo- site sacro-iliac junction, three inches and a half on both sides. From the tu- berosity of one ischium to that of the other, two inches and a half. From the tuberosity to the coccyx, three inches. From the spine of one ischium to that of the other, three inches and a half. From the lower part of the sym- physis pubis to the hollow of the sacrum, four inches; distance of the rami of the pubis, five-eighths of an inch. This pelvis has a triangular brim; for it will be observed, that the brim above the foramen thyroideum measures nearly an inch across, and there- fore there is a considerable space betwixt the two ossa pubis, gradually, how- ever, becoming narrower toward the junction of the bones; but little advan- tage in delivery can be gained from this. When we examine it with a view to determine what bulk may be brought through the brim, we find that it is by its shape virtually divided into two cavities, one on the right, and the other on the left side, and the short diameter of the one is six-tenths of an inch, and that of the other seven-eighths of an inch; therefore no art can bring a child at the full time through it. In this pelvis, the sacrum has fallen so forward at the top, that in a stand- 304 ing posture the face of that bone is almost horizontal, and its under part with the coccyx is bent forward like a hook. The vertebra are much distorted. NOTE 5, p. 31.—This is the case in a pelvis where the distance from the part of the brim above the foramen thyroideum on one side, across to tiie same part on the opposite side, is only five-eighths of an inch. From the right acetabulum to the sacrum is an inch and three-eighths. From the left is one inch. This pelvis at the brim is externally triangular, but it is, from the near approximation of the bones, virtually semicircular, the space betwixt the two ossa pubis being so trifling as not to merit consideration; and the diameter of the brim here is one inch, exclusive of the small slit betwixt the bones. The sacrum in this pelvis is very much curved, and the outlet is small. NOTE 6, p. 33.—Dr. Denman mentions a fatal case of this kind, to which Dr. Hunter was called. The child was delivered by the crotchet, but the patient died on the fourth day. A firm fatty excrescence, springing from one side of the sacrum, was found to have occasioned the difficulty. Vide Introd. Vol. II. p. 72.—Baudelocque, in the 5th vol. of Recueil Periodique, relates a case, where, in consequence of a scirrhous tumour adhering to the pelvis, the crotchet was necessary. In a subsequent labour, the cesarean operation was performed, and proved fatal to the mother.—Dr. Drew records an instance where the tumour adhered to the sacro-sciatic ligament, and was successfully extirpated during labour. It was 14 inches in circumference. Vide Edin. Journal, Vol. I. p. 23. NOTE 7, p. 33.—A fatal case of this kind occurred to Dr. Ford, and is noticed by Dr. Denman. Vol. II. p. 75.—Another fatal instance is recorded by M. Baudelocque, L'Art. section 1964. See also a case by Dr. Merriman, Med. and Cliir. Trans. HI. 47. This ovarium contained a fluid, and probably might have been opened during labour with advantage. NOTE 8, p. 33.—Several cases of this kind have been met with, and in one related by M. Brand, and noticed by Dr. Sandifort in his Obs. Anat. Path. the woman died undelivered. NOTE 9, p. 33. M. Pclletin details several cases of tumours within the pelvis, some of them fatty or fibrous, and easily turned out, merely by mak- ing an incision over them, through the vagina; one encysted containing puri- form matter; and one about an inch long, of a cartilaginous nature, adher- ing to the descending branch of the pubis, the vagina being divided, it was cut off with scissars. Clinique Chirurgicale, Tom. 1.203, 206, 224, 228, 250. Mr. Park likewise relates several cases, chiefly of tumours containing liquid, or soft contents, and which were pierced from the vagina during labour. Med. Chir. Trans. II. 293. CHAP. VII. NOTE 1, p. 36.—The following are the dimensions of a very krge pelvis which I possess. The conjugate diameter is four inches and three fourth ; the lateral, five inches and five-eighths; the diagonal, five inches and a half 305 From the symphysis pubis to the sacro-iliac junction, five inches. From the top of the arch of the pubis to the sacrum, is five inches and three-eighths. From one tuberosity of the ischium to the other, is five inches and a half-; and the arch is very wide. Depth of the pelvis at the sacrum without the coccyx, five inches. Breadth of the sacrum at the top, four inches and seven- eighths. Depth of the pelvis at the sides, four inches. CHAP. IX. NOTE 1, p. 46.—In birds, we find that the ovaria contain a great number of yolks of different sizes. Those wliich are nearest the wide canal called the oviduct which leads to the cloaca, are largest, whilst those remote from it are very minute. The full grown yolk is detached from the ovarium, and in its passage down is furnished both with the albumen and the neces- sary membranes and shell. In viviparous fishes, as the skate, ray, &c. the same structure obtains. These animals have two ovaria, containing eggs of different sizes; the smaller are white, the larger yellowish, and they pass down to an oviduct, which contains a glandular body that furnishes the cover- ing of the egg. Each ovary has a separate oviduct, which forms a vast sac, that terminates in the sides of the cloaca, by orifices that have a duplicature like a valve. The cloaca itself forms an ample reservoir, that seems more like a continuation of the oviduct than the termination of the rectum. In oviparous fishes, the ovaria are known under the name of roes, and all the visible eggs are of the same size, and so numerous, that some contain above 200,000. They are enveloped in a fine transparent membrane ; and septa from this envelope, divide the internal parts, and furnish points of attach- ment to the ova, which are expelled previous to fecundation. These are called oviparous fishes, and have, properly speaking, no oviduct. The ovaria of frogs resemble those of fishes, and the ova are, previous to expulsion, enveloped in a glary fluid. In the slug we find both testicles and ovaria. The ovarium is a grape-like tissue, containing numerous small grains, or ova, attached by pedicles, which are canals that lead into the oviduct. This is a serpentine canal, that after having adhered to the testicle, opens in the common cavity of generation, in which also the penis or duct from the tes- ticle opens, and during copulation, the two individuals mutually impregnate each other. The ovaria of the adder are like strings of beads. In many quadrupeds, the ovaria contain ova almost as distinct as some of those animals I have just noticed. The hedgehog has an ovarium like a bunch of grapes; and the ovarium of the civet has a knotted surface, and resembles a packet of httle spheres : the ovarium of the didelphis is also vesicular. The common sow has also an ovarium somewhat resembling, ex- ternally, that of oviparous animals. Most other quadrupeds have an ovarium more smooth and somewhat oblong in shape, and in general the tube and ovarium are unconnected, as in the human female; but in the otter, my brother observed, that both were contained in a kind of capsule formed by VOL. I. R» 300 the peritoneum, so that ventral extra-uterine pregnancy cannot take place in this animal. - CHAP. X. NOTE 1. p. 54.—The females amongst the Bosjesmans have the nymphae sometimes five inches long. Their colour is a livid blue, like the excrescence of a turkey. Vide Barrow's Travels in Africa, Vol. I. p. 279. NOTE 2, p. 54.—On the shores of the Persian gulph, among the Christians in Abyssinia, and in Egypt among the Arabs and Copts, girls are circumcised. Niebuhr says, that at Kahira, the women who perform this operation are as well known as midwives. Travels, Vol. II. p. 250.—Dr. Winterbothom, in his account of Sierra Leone, Vol. II. p. 239, says it is practised among the Mandingo, Foola, and Soosoo women. NOTE 3, p. 54.—M. Causaubon has inserted a memoir on this subject, in the 1st Vol. of Recueil Periodique, which contains several useful cases. In one of these, the tumour was produced in the seventh month by a kick, and terminated fatally by hemorrhage.—In another given by Sedillot, the labia became prodigiously distended during labour, and the head of the child could not be touched. The labia were torn by the attendant. Afterward the child was delivered with the lever.—In cases related by Baudelocque, Brasdor, &c. the tumours were opened, and the vagina plugged whilst the wound was stuffed with lint dipped in solution of alum, to prevent hemorrhage. NOTE 4, p. 54.—In a case related by Mr. Reeve, the tumour which I sus- pect proceeded from the rupture of the nympha, was perceived first in perineo, but soon occupied all the left labium, which was enormously distend- ed. The pain at first was so great as to cause syncope. The parts sloughed, and discharged pus and clotted blood. Bark was given, and she got well. Lond. Med. Journ. Vol. IX. p. 119. NOTE 5, p. 54.—Vide case by Dr. Maitland, in Med. Comment. Vol. VI. p. 95.—Dr. Perfect relates a case, where it burst itself before the child was born, and discharged much blood, Vol. II. p. 63.—In another, which ended fatally, the tumour burst after dehvery, and discharged five pounds of blood. Vide Plenk Elementa, p. 111.—Case by M. Sedillot, in Recueil Period. Tom. I. p. 260. NOTE 6, p. 54.—Vide cases by Dr. Macbride in Med. Obs. and Inq. Vol. V. p. 89. NOTE 7, p. 55.—In Mr. Blagden's case, related by Dr. Bailhe, the woman soon after dehvery had violent bearing-down pains, as if another child were to be born. A monstrous swelling appeared in the right labium, extending to the perinxum. A large incision was made, which did not heal till the 2lst day. Med. and Physical Journal, Vol. II. p. 42. NOTE 8, p. 55.—Vide Fichet de Flechy, Observ. p. 375. The patient was cured by introducing a compress into the vagina, and dressing the sore with digestive ointment. 807 NOTE 9, p. 55.—Le Dran relates a case, where above 20 ounces of blood were evacuated by incision. Consultations, p. 413. NOTE 10, p. 55.—-Mr. Simmons cut off a clitoris, which formed a tumour nine inches in length, and fourteen in circumference at the largest end. The circumference of the stem was five inches. Med. and Phys. Journal, Vol. V. p. 1. NOTE 11, p. 55.—Schmucker's Miscel. Surg. Essays, art XXIII. NOTE 12, p. 56.—Upon this subject, see Arnaud on Hermaphrodites. In a child aged three years, I found the mons veneris prominent, and, as well as the labia, covered with a considerable quantity of red hair. The labia were large and thick, hke those of a grown woman, but shorter. Their in- ner surface was white and rugous, until near the orifice of the vagina, where the skin was red. At the top the labia divaricated, and showed a large clitoris, which hung down like the penis; it was upwards of an inch long, and about half an inch in diameter, and furnished with a thick wrinkled prepuce. It had a distinct glans, at the end of which was observed something hke a per- foration ; but on raising it up, this was seen to be only the extremity of a deep sulcus, which extended all the way to the urethra, or orifice of the vagina. It resembled the male urethra slit up. The sides of this were formed by the nymphae. A httle before the orifice of the urethra, there was a longitudinal eminence, hke the veru montanum. The vagina was shut up by the hymen. The uterus was large, hke that of a girl of fourteen years of age, and was shaped hke hers. The ovaria were of corresponding size; one of them lay on the psoas muscle, the other was loose in the pelvis. The tubes were fimbriated at their extremity, but in their course were knotted and serpentine, hke the commencement of the vas deferens. The uterus was very vascular, and had an inflamed appear- ance. Its mouth was apparently impervious. In a male child that I lately saw, the external parts resemble those of the female. The scrotum is cleft like the vulva, the penis consists only of cor- pora cavernosa, and the urethra opens between the labia formed by the scrotum. NOTE 13, p. 56.—The same effect may be produced, by a continuation of the skin being extended over the parts. It must be cut up. See a case by M. Larrey, in Rapport General de la Societe Philomatique, Tom. II. p. 86. NOTE 14, p. 56.—Vide case of a patient of Dr. Chamberlain's, in Cow- per's Anatomy.—Case by Mr. Fryer, in Med. Facts and Obs. Vol. VIII. p. 132. NOTE 15, p. 56.—Case by Mr. Sherwin, in Med. Records, &c. p. 379. NOTE 16, p. 56.—Case by Mr. Kaeymer, in Med. Annals, VoL VI. p. 347. By Mr. Eason, in Med. Comment. Vol. II. p. 187, and a variety of other cases. This, in every instance I have known, has been the greatest complaint. NOTE 17, p. 56.—Dr. Smellie candidly acknowledges, that in one instance he took the protrusion of the hymen, for the membranes of the ovum, forced 308 down by lahour pains. These pains were accompanied with suppression of urine. He let out about two quarts of blood. Col. I. n. i. c. 6. NOTE 18, p. 56—In a case related by Benevoli, the belly was very much swelled, and the urine suppressed. He attempted to pass the catheter, but without success. Next day he repeated his endeavour, and pushing with more force than prudence, considering his object, he ruptured the hymen, and immediately a great quantity of dark matter was evacuated, even to the extent of 33 pints.—See also Mr. Fryer's case.—Mr. Warner relates the case of a httle girl, where the hymen was continued half way over the orifice of the urethra. The effects were at first attributed to stone in the bladder; but the nature of the case being made out, she was cured by dividing the hymen. Cases, p. 75. NOTE 19, p. 56.—In a case by Mr. Bardy, the patient, who was 15 years of age, had every month, for some days, pain in the uterine region. The external parts were greatly protruded and stretched as in labour, and the nymphs formed merely two lines. The anus was thrust backward and dis- tended, and she passed the urine and faeces with great pain ; the hymen from irritation was covered with scab, the health had suffered. Six pounds of thick gelatinous matter were evacuated by incision. Med. and Chir. Re- view for September, 1807. NOTE 20, p. 56.—In Mr. Fynney's case, the part to be divided was very thick; and in Dr M'Cormick's case, the vagina seemed to be in part imper- vious. Med. Comment. Vol. n. p. 1S8.—In general the membrane is thin. NOTE 21, p. 56.—Vide Mr. Niven's case, in Med. Comment. Vol. IX. p. 330. The symptoms gradually abated. NOTE 22, p. 56.—M. Baudelocque mentions an instance where the hymen resisted, for half an hour, the strong action of the uterus. Note to Section 341. NOTE 23, p. 59.—Upon this subject, vide La Motte's Traite ; and cases and observations by Noel, Saucerote, Trainel, and Sedillot, in the fourth and seventh Vol. of the Recueil Periodique. Dr. Denman mentions an instance where the perinaeum was not torn up, but perforated by the head. NOTE 24, p. 59.—In a case where the vagina would not admit the point of the little finger, the child was delivered after eighteen hours labour. Plenk Elementa, p. 113. See also Van Swieten. NOTE 25, p. 59.—This may produce bad effects, from retention of the menses. M. Magnan relates the case of a girl, aged 22 years, who had been subject to monthly colics and suppression of urine. An incision was made through the membrane, and two pounds of blood let out. Hist, de la Societe de Med. pour. 1776, art. II. NOTE 26, p. 59.—In this case the faeces do not always pass continually. The patient has been known not to have a stool once in a fortnight; which probably depended on the faeces being indurated, and the communication small. NOTE 27, p. 59.—In the 33d VoL of the Phil. Trans, p. 142, there is a 309 case related, where there was a kind of double vagina, separated by a trans- verse septum or membrane. The orifices were very small. During labour, the pain was so great as to produce convulsions. She was delivered, by laying the two passages into one. Chapman relates a case of malformation, where the woman was impregnated, and in labour all the forcing was felt at the anus. From this an opening was made through into the vagina, and the child was born per anum. Portal mentions a girl, who had only avery small aperture at the vulva, for the evacuation of the urine ; the menses came from the rectum; nevertheless, she became pregnant. Before delivery, the orifice of the vagina appeared, and she bore the child the usual way. Precis de Chirurgie, Tom. II. p. 745. NOTE 28, p. 59—Richter in Comment. Gotting. Tom. in. art. 2. relates a case of a girl aged 20 years, who for three years had been subjects to vio- lent pains about the sacrum, with tremors and syncope every month. The vagina was found to be closed at the upper part, in consequence, it was im- agined, of a variolous ulcer in infancy. Fluctuation was felt in the vagina, when pressure was made with the other hand on the abdomen. The con- traction was opened, and a quantity of blood let out. NOTE 29, p. 60.—In some parts of Africa, the vagina is made impervious, in order to prevent coition. This operation is generally performed betwixt the age of eleven and twelve years. Brown's Travels, p. 349. NOTE 30, p. 61.—Burton relates a case, where the prolapsed vagina was mistaken for part of the placenta, and rudely pulled away, by which the vagina and bladder were torn. System, p. 170. Stollers relates a case, where this was complicated with calculi. These being removed, the parts were reduced, and a cure obtained. Cases, Obs. 2. NOTE 31, p. 61.—Mr. Henry Watson, in the Med. Communications, Vol. I. p. 162, called the attention of practitioners to this disease. In a case he relates, he drew off in the month of June, four gallons of fluid, by tapping the vagina; and immediately after this she passed the urine freely, which she coidd not do before. She required again to be tapped in two months, and died in November* The left ovarium was found to be converted into a cyst, about the size of a sow's bladder, but it had not been touched by the trocar. In one case, he punctured with a lancet instead of a trocar, but this was succeeded by troublesome hemorrhage. The good effects of tapping are also seen in a case related by Mr. Coley, in Med. and Phys. Journal, Vol. VII. p. 412. In this two gallons of water were drawn off* and she continued well for five months, after which, dropsical symptoms returned, and altHough diuretics gave her some relief, yet she was at last cut off. In the case of Mrs. Jarritt, related by Sir W. Bishop, in Med. Commun. Vol. II. p. 360, pain was felt in the right side of the belly, after parturition, accompanied with tumefaction. In two years the vagina became prolapsed, the tumour being four inches in diameter. The tumour was punctured twice; the first time 46 pints, the second 51, were drawn off. Diuretics had no effect. In a case related by Dr. Denman, the woman was pregnant, and no operation was per- 310 formed. On the fourth day after her dehvery, after a few leose stools, she expired, Introd. Vol. I. p. 150. NOTE 33, p. 71.—In a case of this kind, described by Mr. Patton as a spasmodic affection of the neck of the bladder, calomel appeared to cure the complaint. London Med. Journal, Vol. X. p. 360. The use of the bougie may be proper. NOTE 34, p. 71.—Morgagni relates an important case, where there was a hard painful tumour in the hypogastric region, accompanied with fluor albus, uterine hemorrhage, and stillicidium of urine. After death, the bladder was found very large and scirrhous, with two large bodies in the cervix, prevent- ing the urine from being retained. The uterus was diseased only in con- sequence of its vicinity to tiie bladder. Epist XXXIX. art. 31. NOTE 35, p. 72.—Of this disease I have never seen an instance ; but Dr. Bailhe mentions a case, in which the greater part of the bladder was filled with a polypus. Morbid Anat. p. 298. NOTE 36, p. 72.—The patient to whom I allude, had, I understood, four years before her death, been dehvered with the forceps, and soon afterwards had incontinence of urine. I found a large perforation in the bladder, exact- ly resembling the fauces without an uvula. The uterus was a little enlarged and indurated; and its mouth, which was ulcerated and fungous, lay in this opening, projecting into the bladder, and closing up the communication be- twixt tiie bladder and vagina. NOTE 37, p. 73.—In a case related by Sandifort, the suppression of urine was always attended with convulsive cough. Lib. I. cap. 5. And in a case related by Dr. J. Hamilton, where prolapsus took place before parturition, the muscles of the body were spasmodically agitated. Cases, he. case 9. NOTE 38* p. 74.—Mr. Sharp mentions a case, where they grew in small quantity upon the orifice, producing excruciating torment till they were ex- tirpated. Critical Inq. p. 168. NOTE 39, p. 75.—In the instance related by Mr. Warner, the urine was voided in drops with great pain, especially about the menstrual period, and she sometimes even had convulsions. He dilated the urethra, by inclining the catheter to one side and thus saw two excrescences near the upper end. He divided or laid open the urethra, and cut off the excrescences successfully with scissors. Cases, p. 309. NOTE 40, p. 75.—In the patient of Mr. Hughes, the disease was taken at first for prolapsus uteri, for there was a substance filling the os externum, and appearing without the vidva. It was a spongy excrescence from the whole circumference of the meatus. It was drawn out with a thread passed through it, and then cut off. Strangury, with pain above the pubis, and fever, took place, on which account the catheter was introduced. Suppres- sion of urine repeatedly occurred; and as it was often difficult to introduce the catheter, the semicupium was employed, and always with advantage ; but once after it, she became faint, and the limbs were convulsed. A stricture being suspected at the upper part of the urethra, a bougie was introduced, 811 and kept in the canal, wliich removed the symptoms. Med. Fact, and Obs. Vol. m. p. 26. NOTE 41, p. 75.—In Mr. Jenner's case, the irritation of the bladder was great, and the menses were irregular. A fungus was found filling the orifice of the urethra ; this was cut off, and the bougie used for an hour every day for a fortnight; a httle before the extirpation, a hemorrhage took place from the excrescences. Vide Lond. Med. Journal, Vol. \'U. p. 160. NOTE 42, p. 75.—M. Sernin relates a case of a girl eleven years of age, who from her fifth year had been subject to frequent attacks of difficuly in voiding the urine. He had an opportunity of examining her after a violent attack, and found a cylindrical body, 4 inches long, projecting from the vul- va ; and whenever she attempted to make water, this projection swelled up. It was amputated with success. Recueil Period, torn. XVH p. 304. NOTE 43, p. 75.—In Dr. Chamberlain's patient, who had the hymen im- perforated, the urethra was so ddated as to admit the finger; and Portal found it, in an analogous case, dilated so as to form a cul-de-sac, admitting the point of the thumb. Cours d'Anat. Medicale, Tom III. p. 476. NOTE 44, p. 76.—Morgagni mentions a porter's wife, in whom the uterus was found not above an inch long, and without any ovaria. The pudendum was extremely small, and there was scarcely any appearanc of a clitoris. In the Phil. Trans, for 1805, there is a case where the uterus of a woman, 29 years of age, was not larger than in the foetal state, and scarcely any appearance of ovaria. She ceased to grow at ten years of age, had no hair on the pubis, never menstruated, and had an aversion to men. I have seen the uterus of the adult not larger than that of a child; the woman never menstruated, and had very flat breasts. NOTE 45, p. 76—Columbus dissected a woman who always complained of great pain in coitu. The vagina was very short, and had no uterus at its ter- mination. Fromondus relates an instance, where the place of the os externum was occupied with a cartilaginous substance. Morgagni was consulted by a barren woman, whose vagina was only a third part of the usual length, and its termination felt firm and fleshy. He advised dissolution of the marriage. M. Meyer in Schmucker's Essays, mentions a case where the vagina and uterus were wanting, but the ovaria existed. The labia and clitoris were small, and there were no nymphae. Mr. Ford dissected a child who had no vagina, uterus, or ovaria. The urethra and rectum terminated close to each other. Med. Facts, Vol. V. p. 92. NOTE 46, p. 76.—Vide Hist.de l'Acad.de Sciences, 1705,p.47.—Haller Opusc. path. 60. AcrelPs cases.—Purcel in Phil. Trans. LXIV. p. 474.— Canestrini in Med. Facts, Vol. HI. p. 171.—Valisneri met with a double uterus and double vulva. Opera, Tom. III. p. 338.—Dr. Pole describes a double uterus in the 4th Vol. of Mem. of Medical Society, p. 92. NOTE 47, p. 76.—Littre found it almost closed, by a continuation of the 312 inner sur/ace of the vagina. Mem. de l'Acad. de Sciences, 1704, p. 27; and in the seventh month of pregnancy, closed by a glandular substance, 1705, p. 2.—Morgagni found it shut with a membrane. Epist. XLVL art. 17.— Boehmer quite shut up. Obs. Anat. fasc. 2, p. 62.—Ruysch saw it so small as scarcely to admit a pin; and Sandifort so well closed, that nothing but air could be forced through it. Obs. Anat. Path, lib II. c. ii. p. 67. NOTE to Section 26, p. 80.—A peculiar growth is described by Dr. Clark under the name of cauliflower excrescence, which is probably of tiie nature of that I speak of, but I never have seen it after death, and therefore cannot be certain. It springs from the os uteri, the base is broad, the surface granulated, the substance brittle, and the fragments broken off white ; pres- sure does not cause much pain, but the patient has more or less pain at times, but not of the lancinating kind. The discharge is at first like fluor albus, but frequently becomes watery and transparent, but stiffens the linen. When the excrescence is large, the discharge is so great as to wet 10 or 12 napkins daily, and occasion fatal debility. The progress is variable, some- times it is so rapid that in 9 months the cavity of the pelvis is filled by it. The only treatment that bids fair to give relief, is the application of a liga- ture, but the peculiarity is, that when the vessels are constricted by this during life, or collapse after death, the sohdity of the tumour is lost, and it resembles merely a glary substance. Trans, of a Society, &c. Vol. III. p. 321. NOTE 48, p. 81.—Vide Stalpart Vander Wiel, obs. 87.—Segerus in Mis. Cur. 1671, obs. 121. Notwithstanding these cancerous excrescences about the os uteri, a woman may conceive. Dr. Denman relates a case where there was a large excrescence in the gravid state, with profuse bleeding. The head of the child was lessened, but the woman died undelivered. Vol. II. p. 65. When the os uteri has been affected with scirrhus, and the woman has conceived, the uterus has sometimes been ruptured, or the woman died un- delivered. Hildanus, cent. I. obs. 67. Horstius Opera, Tom. II. lib. 2. obs. 5. Blancard Anat p. 233. Hist, de l'Acad. de Sciences, 1705, p. 52. NOTE 49, p. 82.—Le Dran attended a patient who had all the symptoms of scirrhous uterus, and, by examination, fungous excrescences were found shooting down into the vagina. The pain was continual, and could only be mitigated by the constant use of opium. Urine was discharged by the va- gina, and after death the bladder was found to be perforated. The fundus and body of the uterus were not much diseased. NOTE 50, p. 83.—Absolute abstinence has been recommended by Pou- teau, Qiuvres Post. Tom. p. 105. He relates a case, which was cured by confining the patient to eau de glace.—Mr. Pearson, p. 113, gives two suc- cessful cases. In the first, the uterus was enlarged and retroverted, but by very spare diet, was restored to its natural state. NOTE 51, p. 85.—Vide Mem. de l'Acad. de Chirurg. Lieutaud relates a case of a woman who had a tumid belly, and complained of great pain. The womb was not much larger than usual, but it was almost bony. Hist. Anat Med. p. 320.—Grandchamp found an osseous tumour, as large as the fist, 313 inclosed in a sac, betwixt the uterus and bladder. It produced constant ischuria, relieved only by lying on the back. Med. and Phys. Journal, Vol. HI. p 587. NOTE 52, p. 90.—Gaubius relates a case, where it was complicated with prolapsus uteri. After a length of time, severe pains came on, and in an hour a large stone was expelled; next day a larger stone presented, but could not be brought away until the os uteri was dilated. From time to time after this, small stones were expelled; but at last she got completely well. NOTE 53, p. 91.—In a case which occurred to the late Mr Hamilton of this place, the polypus was expelled by labour pains, but the woman died exhausted.—In a case related by Vater, it was expelled when the woman was at stool. Haller, Disp. Chir. Tom. III. p. 621. See also a case in the same work, p. 611, by Schunkius.—In the patient of Vacoussain, the polypus was expelled after severe pain; its pedicle was felt to pulsate very strongly, but a ligature being apphed, the tumour wsis cut off. Instantly the ligature dis- appeared, being drawn up within the pelvis, but on the third day it dropped off. Mem. de l'Acad. de Chir. Tom. III. p. 533. NOTE 54, p. 91.—Vide case by Vater, in Haller, Disput. Chir. Tom. IH. p. 621.—In the case furnished by M. Espagnet, an attempt was made to intro- duce the catheter; but a straight one being employed instead of a curved one, or an elastic catheter, it was found necessary previously to make an in- cision in the fore part of the polypus, which had protruded. Mem. de l'Acad. de Chir. Tom. IH. p. 531. NOTE 55, p. 94—Dr. Denman, Vol. I. p. 94, mentions a young lady who had suffered long from uterine hemorrhage. A polypus was found just to have cleared the os uteri ; a ligature was applied, but as she felt severe pain, and vomited, it was slackened. Every attempt to renew the ligature had the same effect. In six weeks she died, and it was found that the uterus was inverted. • NOTE 56, p. 94.—M. Herbiniaux, Tom. H. obs. 17, relates a case. The ligature seemed to act on an inverted portion of the womb, producing pain, fever, and convulsions; it was slackened, but afterwards, notwithstanding a renewal of dreadful suffering, it was, with a perseverance hardly to be com- mended, employed so as at least to remove the polypus—Desault found, after having applied a ligature round a polypus, and cut the tumour off next day, that part of the fundus uteri was attached to the amputated substance; the patient did well. Baudelocque supposes that some cases, related as ex- amples of amputation of inverted uteri, were merely polypi, accompanied with inversion. Recueil Period. Tom. IV. p. 115. NOTE 57, p. 95.—Dr. Denman, Vol. I. p. 95, relates a case of polypus with broad stem, which was supposed to be a cancer of the uterus. The ligature was applied,and in eight or nine days it came away; but when the polypus was removed, another substance, nearly of the same size, was found to hava grown into the vagina. The woman died in a month. I have seen the com- mon polypus combined with an indurated thickening of the uterus, and fun- VOL. I. s S 314 gous or flocculent state of the cavity. In one case of this kind, the uterus and rectum freely communicated by ulceration. See also some cases in Trans, of a Society, &c. Vol. HI. NOTE 58, p. 96.—Sometimes the mass appears to be putrid, and is ex- pelled with great hemorrhage. Vide case by Dr. Blackbourn, Lond. Med. Journal, Vol. n. p. 122.—Sometimes it has a kind of osseous covering, as in the case by Hankoph, in HaUer, Disp. Med. IV. p. 715. NOTE 59, p. 97.—In the Hist, of Acad, of Sciences for 1714, is the case of a woman who received a fall in the third month of pregnancy. The belly, however, increased in size till the fifth, when itbegan to lessen. In the sixth she was dehvered of a bag, as large as the fist, with the placenta and foetus of the size of a kidney bean. In this case, hydatids were not formed; but in the History for 1715, is a case, where tiie woman, falling in the second month, had the ovum converted into hydatids, which were expelled in the tenth month. As hydatids often succeed to genuine pregnancy, the symp- toms may at first be exactly the same with those of pregnane}', nay, even motion may be felt, but afterwards the child may die, and hydatids form.— Mr. Watson, in the Phil. Trans. Vol. XLI. p. 711, gives a case, where there was, for a long time before the expulsion of hydatids, a quantity of blood discharged every night; pains at last came on, and expelled many hydatids. In this case, the symptoms of pregnancy were evident from Nov. to Feb. When the ovum is blighted, the belly ceases to enlarge in the due propor- tion, and the breasts become flaccid. Dr. Denman gives an engraving of a diseased ovum: and Mr. Home relates a case, where the patient, after being attacked with flooding, vomiting, and spasm in the abdomen, died. On opening her, the womb was found filled with hydatids, and its mouth a little dilated. Trans, of a Society, &c. Vol. II. p. 300.—Such cases as I have seen have been attended with a consider- able discharge; but as a great part of it was watery, it made a greater ap-i pearance than the real quantity of blood would have caused. In a case related by Valleriola, p. 91, the woman had at first her usual symp- toms of pregnancy, but in the eighth month expelled hydatids.—Pichart in Zod. Med. Gall. an. 3, p. 73, relates a similar case, but the hydatids were ex- pelled in the fourth month without hemorrhage. Other cases of hydatids are to be found in Tulpius, lib. HI. c. 32. Shenkius, p. 685. Mercatus de Mulier. affect, lib. HI. c. 8. Christ, a Veiga Art Med. lib. III. § 10. c. 13, relates an instance of 60 hydatids, as large as chesnuts, being expelled. Stalpart Vander Wiel, Tom. I. p. 301, mentions a woman, who in the ninth month, after enduring pains for three days, expelled many hydatids, and the process was followed by lochia. Lossius, Obs. Med. hb. IV. ob. 16, men- tions a widow who for several years had a tumid belly: after death, hydatids were found in utero. See also Mauriceau's Observations, obs. 367. Ruysch, jObs. Anat. Chir. p. 25. Albinus Anat. Acad. lib. I. p. 69. and tab. HI. fig. 1, describes in an abortion, the commencement of this change. The vesicles are not larger than the heads of pins. Wrisberg describes a more advanced stage in Nov. comment. Gotting. Tom. IV. p. 73; and Sandifort, in his Obs. 315 Anat. Path. lib. H. c. 3. tab. VI. fig. 5, has a case extremely distinct. See also Haller, Opusc. Path. ob. 48. Vigarous, Malad. &c. Tom. I. p. 385, proposes mercury to kill the hydatids. He knew an instance where the woman discharged hydatids always when she went a la garde-robe. Mr. Mills relates a case, where the woman betwixt tiie second and third month, had symptoms of abortion, and afterwards, in the fifth or sixth, expelled above three pints of hydatids. Vide Med. and Phys. Journal, Vol. H. p. 447. When the mass is expelled, it is found either to consist entirely of small vesicles, or partly of vesicles, and partly of more solid remains of the ovum, or coagulum of blood. NOTE 60, p. 99.—Hildanus relates a case of this kind in his own wife, did- cissima et charissima conjux mea. Hydatids may also be combined with preg- nancy. The same author tells us of a woman who, in the fifth month, was dehvered of a mola aquosa, or vesicles containing ten pounds of water; she did not miscarry, but went to the full time. NOTE 61, p. 100.—Kirkringius, p. 28, considers dropsy of the uterus as impossible, and says, that every case of collection of water depends on a large hydatid. Dr. Denman seems to be much of the same opinion. But we find instances where water is accumulated and repeatedly discharged, ap- parently from the removal of a temporary obstruction. Fernelius relates a case, where the woman always before menstruation discharged much water. Path. lib. VI. c. 15. And M. Geoffroy describes a case of repeated discharge. Vide Fourcroy la Med. Eclare, Tom. II. p. 287. A case is related by Turner, where the external membrane of the uterus was said to be distended with water. The menses were suppressed, and a secretion of whitish fluid took place from the breasts. Phil. Trans. No. 207. NOTE 62, p. 102.—Sometimes the situation of the abdominal viscera is very much altered. In Mr. White's case, the liver was found to descend to the lower part of the belly, and the diaphragm was lengthened so as to allow the stomach to reach the umbilical region. Vide Med. Obs. and Inq. Vol. III. p. 1. In a complicated case, related by Schlincker, the pylorus hung down to the pubis. Haller, Disp. Med. IV. 419. NOTE 63, p. 102.—This point is very well considered by Vcrdier, in his paper on Hernia of the Urinary Bladder, in the first Vol. of Mem. de l'Acad. de Chir. See also a paper by M. Tenon, in Mem. de l'lnstitute, Tom. VI p. 614.—Mr. Paget relates a very interesting case of prolapsus uteri, in which the bladder became retroverted, lying above the uterus. It could not de- scend before it, or along with it, being filled with a calculus, weighing 27 ounces, and others of a small size. Some parts of the bladder were an inch thick; a catheter could not be introduced. Med. and Phys. Journal, Vol. VI. p. 391. NOTE 64, p. 103.—Ruysch, feeling some hard bodies in the tumour formeg by the protruded parts, cut out 42 calculi from the bladder. M. Tolet ex- tracted fifty, and afterwards cured the woman with a pessary. Duverney met with large calculus in the bladder, with procidentia uteri; and Mr. Whyte 316 relates a similarfact Med. Obs. and lnq. Vol. in. p. 1. See also Deschamps Traite de la T,jjlie, Tom. IV. p. 158. NOTE 65, £. 103.—Kirkringius says, nemo vitlit, nemo sensit, decepti oir.nes imagine falsa, alios decipiunt,- laxitas qu&dam colli qute extra pudendum pro- minet hec nobis fecit hidibrio. Opera, p. 48. Vide also Job a Meckren, Observ. Chir. c. 51. Barbette Chirurg. c. 8. Roonhuyscn, Obs. Chir. part I. ob. 2. NOTE 66, p. 103.—Dr. Monro mentions a procidentia uteri, in a very young girl. It was preceded by bloody discharge. Works, p. 535. Another case is related by Saviard, Obs. 15, in which the prolapsed uterus was mis- taken for the male penis; and as Goldsmith's soldier believed they would allow him to be born in no parish, so this girl was in danger of being deter- mined to have no sex. NOTE 67, p. 104.—Morand relates the case of a woman who had foetid dischai'ge from the vagina, accompanied with pain. On examination, fungous excrescences were discovered in the vagina, and amongst these a hard sub- stance, which being extracted, was found to be part of a silver pessary The vagina contracted at this spot and thus, though in a disagreeable way, pre- vented a return of the prolapsus. Pessaries have also ulcerated through to the rectum; and Mr. Blair mentions a woman in the Lock Hospital, who had introduced a quadrangular piece of wood into the vagina as a pessary, and which ulcerated thus into the rectum, producing great irritation. Med. and Phys. Journal, Vol. X. p. 491. It is likewise necessary, if the pessary have an opening, in it, to observe that the cervix uteri do not get into the open- ing, and become strangulated. NOTE 68, p. 106.—See Rossuet, Plater, and Platnf r, Inst. Chir. section 1447. Wedelius de Procid. Uteri, c. 4. Volkamer, in Miscel. Cur. an. 2. ob. 226. Another case may be seen in Journal de Med. Tom LXVHI. p. 195. Pare CEuvres, p. 970.—Carpus extirpated it with success. Vide Longii Epist. Med. lib. II. epist. 39.—Slevogtius relates a distinct case, where the womb was found in the vagina, as if in a purse. Dissert. 12.—Benevenius says, he saw a woman whose uterus sloughed off. De Mirand. Morb. Causis, cap. 12.—Dr. Elmer supposes he has met with a similar case. Med. Phys. Journal, Vol. XVIII. p. 344.—The latest case is related by Laumonier. The patient was long subject to prolapsus uteri, but at last the womb, with the vagina, was forced out so violently, that she thought all her bowels had come out. At the upper part of the tumour there was a strong pulsation. It was extirpated chiefly by ligature. The woman died some years after this, and the womb was found wanting. La Med. Eclare', par Fourcroy, Tom. IV. p. 33. M. Baudelocque, however, says, that tiie uterus was only partially ex- tirpated. Vide Recueil Period. Tom. V. p. 332. NOTE 69. p. 106.—Harvey relates a case, where the tumour was as large ' as a man's head, ulcerated, and discharged sanies. It was proposed to ex- tirpate the prolapsed uterus, but the following night a foetus was expebYil, spiihama longitudine. Opera, p. 558. See also a ease by Mr. Autrobus, in Med. Museum, Vol. I. p. 227. 317 NOTE 70, p. 107.—Dr. Burton had a patient, who in the fourth month of pregnancy fell, and was thereafter seized with suppression #f urine. The os uteri was found almost at the orifice of the vagina. He drew off about three quarts of urine, raised up the womb, and introduced a pessary. Sys- tem, p. 156. NOTE 71, p. 107.—Mr. Dray mentions a case where, in the fourth month of pregnancy, the woman was seized with pains, like those indicating abor- tion, accompanied with suppression of urine. The os uteri was very near the orifice of the vagina. This disease proving fatal, the bladder was found to be thickened, enlarged, and in part mortified. Vide Med. and Phys. Jour- nal, Vol. III. p. 456. NOTE 72, p. 107.—Reink mentions a woman who was pregnant of twins. In the fourth month the womb prolapsed, and caused a fatal suppression of urine. The vagina, at the upper part, was corrugated and inverted. Haller, Disp. Chir. Tom. III. p. 585. NOTE 73, p. 109.—Sampson, in the Phil. Trans. No. 140, describes an ovarium filled with hydatids, containing 112 pounds of fluid.—.Willi mentions a tailor's wife, whose ovarium weighed above 100 pounds, and contained partly hydatids, partly gelatinous fluid. Haller, Disp. Med. Tom. IV. p. 447. NOTE 74, p. 109.—In a case detailed by Vater, the patient had symptoms of pregnancy, secreted milk, and even thought she felt motion. The belly continued swelled, and she had bad health for three years and a half, when she died. The abdomen contained much water, and the right ovarium was found to be as large as a man's head, containing capsules, filled with purulent looking matter. The uterus was healthy, but prolapsed, and the ureter was distended from pressure. Haller, Disp. Med. Tom. IV. p. 401. This was not a case of extra-uterine gestation, for the ovarium was divided into cells, and had no appearance of foetus. NOTE 75, p. 109.—In some cases it does not ascend out of the pelvis, or if it do, the inferior part of the tumour sinks again into it. Morgagni relates an instance where the ovarium weighed 24 pounds; and the lower part of it filled the pelvis so well, that when it was drawn out, it made a noise like a cupping glass when pulled away from the skin. Epist 39, art 39. NOTE 76, p. 109.—It may be combined with effusion of water in the ab- dominal cavity. Dr. Bosch's patient had 16 pints of water in the abdomen, and both ovaria were enlarged so as to weigh 102 pounds. Phis patient com- plained of great pain and weight in the lower belly, and over the right hip. She was much emaciated, but the menses were regular. When she was tap- ped, not above two.tea-cupfuls of fluid were discharged. Med. and Phys. Journal. Vol VIII. p 444—Mr. French met with a case of ascites and drop- sy of the ovarium. The ovarium extended from the pubisto the diaphragm. This patient had voracious appetite. Mem. of Medical Society, Vol. I. p. 234. NOTE 77, p. 110.—If only one of the ovaria be enlarged, or if both be af- fected, but only one much increased, the uterus is often not raised, because the ovarium turns on its axis, and the litems lies below it. In a case with 318 wliich I was favoured by Dr. Cleghorn, both ovaria were greatly tumefied, and could be felt on each side of the navel, whilst immediately beneath that, they seemed to be united by a flat hard substance; and when tiie urine was long retained, a fluctuation could be perceived before that part. Upon dissection, a firm thick substance was found, extending from the pubis to the navel, be- twixt the ovaria. This was the uterus and vagina. The uterus itself was lengthened, the cervix was three inches long, and all appearance of os tincx was destroyed. Her complaints began after being suddenly terrified; first she felt severe pain in the right groin, with weakness of the thigh, and soon afterwards perceived a tumour in the belly, and presently another appeared in the left side. She was tapped 16 times. NOTE 78, p. 111.—In a case noticed by Dr. Denman, the labour was ob- structed until the ovarium was emptied, by piercing it from the vagina. The woman died six months afterwards. Introd. Vol. U. p. 74. In Dr. Ford's case, related by Dr. Denman, the crotchet was employed. See also a case by M. Baudelocque, 1'Art des Accouch 1964. NOTE 79, p 112.—Dr. Denman justly observes, that diuretics have no ef- fect, Vol. I. p. 122. And Dr. Hunter remarks, that "the dropsy of the ovarium " is an incurable disease, and that the patient will have the best chance for " living longest under it, who does the least to get rid of it. The trocar is " almost the only palliative." Med. Obs. and Inqu. Vol. II. p. 41. Willi, however, relates a case of 14 years standing, which was cured by diuretics; and it was calculated that the tumour contained 100 pounds of fluid. Haller, Disp. Med. Tom. IV. p. 451. NOTE 80, p. 112.—Dr. Denman advises the operation to be deferred as long as possible, and I beheve he is right; for every operation is followed by re- accumulation, which is a debilitating process; yet it is astonishing how much may in the course of time be secreted, without destroying the patient. Mr. Ford tapped his patient 49 times, and drew off 2786 pints. The secretion was at last so rapid, that three pints and three ounces were accumulated daily. Med. Commun. Vol. II. p. 123. Mr. Martineau tapped his patient 80 times, and drewoff 6831 pints, or 13 hogsheads; at onetime he drew off no less than 108 pints. Phil. Trans. Vol. LXXIV. p. 471. [In the London Medico-chirurgical Transactions, Vol. HI. p. 40. et seq. may be found the history of a remarkable case of ovarian dropsy, by Thomas Chevalier, Esq. P. L. S. &c. The abdomen in this case measured 63$ inches in circumference, and 38 inches from the point of the ensiform cartilage to the top of the pubis. The navel when she sat was on a line with the knee. The quantity of fluid drawn off amounted to 17 gallons. The patient died.] NOTE 81, p. 113.—Le Dran relates two cases in the Mem. de l'Acad. de Chir. Tom. HI. In the first, the cyst was opened, and the woman cured of the dropsy, but a fistulous opening remained, p. 431. In the second, he made a pretty large incision, and introduced a canula into the sac. The operation was followed by fever, delirium, and vomiting; the woman retained nothing but a httle Spanish wine for three weeks. She discharged daily 8 or 10 ounces of red fluid. At length, all of a sudden, 15 ounces of white pus were 319 evacuated, and then the symptoms abated; but a fistula remained for two years; then it healed, p. 442. [Dr. M'Dowell of Danville, Kentucky, relates three cases of extirpation of diseased ovaria, in Eclectic Repertory, for April, 1817. Vol. VII. p. 242. The patients recovered.] Dr. Houston relates the case of a woman in this neighbourhood, in whom lie made an incision 2 inches long into the ovarium, and then with a fir splint turned out a great quantity of gelatinous matter and hydatids. He kept the wound open with a tent, and succeeded in curing the patient. The disease was attributed to rash extraction of the placenta, and had existed for 13 yearJ. It was attended with violent pains. Phil. Trans. XXXIII. p. 5. M. Voison relates a case, which was palliated by tapping, and keeping a fistula open. Recueil Periodique, Tom. XVII. p. 381. And Portal gives an instance, where, by keeping the canula in the wound for a short time, a radi- cal cure was obtained, and the person afterwards had children. Cours d'Anat. Tom. V. p. 554. NOTE 82, p. 113.—De La Porte tapped a woman who had a large tumour in the belly, but nothing came through the canula. He made an incision of considerable length, and, in the course of two hours and an half, extracted 35 lb. of jelly. The lips of the wounds were then brought together. Next day 15 lb. of jelly were evacuated, but presently vomiting and fever took place; and she died on the thirtieth day, having discharged altogether 671b. of fluid. This disease was of sixteen months standing, and was attributed to hemorrhage. Mem. de l'Acad. de Chir. Tom. III. p. 452. Dr. Denman notices the case of a patient, who died the sixth day after in- jecting the ovarium. Vol. I. p. 122. NOTE 83, p. 113.—Dr. Monro, in Med. Essays, Vol. V. p. 773, details the history of a patient who had a diseased ovarium, and in whom the tumour pointed about four inches below the naveL It was opened, but nothing but air came out, followed next day by faeces; on the fifth day some pus was dis- charged. She gradually improved in health, and the tumour of the belly subsided; but in two years afterwards the suppuration was renewed, and she died. In this case, the colon had probably adhered to the ovarium. NOTE 84, p. 113.—Dr. Denman relates the case of a patient, who, having for some time suffered from pain and tenderness about the sacrum and ute- rus, and uterine hemorrhage, was suddenly seized with vomiting, syncope, pains in the belly, and costiveness; presently a tumour was felt in the right side, and this soon occupied the whole abdomen. This patient was cured, after purging a gelatinous fluid. Med. and Phys. Jour. Vol. II. p. 20. ; .. NOTE 85, p. 114.—Dr. Monro relates a case of supposed pregnaney, in the tenth month of which, the tumour was removed by an aqueous discharge from the vagina. In a future attack, however, violent bearing-down pains were excited, and the woman died exhausted. The left ovarium was found greatly enlarged with vesicles. Med. Essays, Vol. V. p. 770. NOTE 86, p. 114.—See Dr. Baillie's Morbid Anatomy, chap. 20. Dr. J. Cleghorn mentions a woman who died ten days after being tapped. The- 320 right ovarium was found greatly enlarged, and had many cells, some con- taining hair, cretaceous matter, fragments of bone and teeth, other gelati- nous fluid Trans, of Royal Irish Acad. Vol. I. p. 80. In Essays Phys. and Literary, Vol. II. p. 300, a case is mentioned, in which the one ovarium con- tained many vesicles; the other contained a mass, like brain, with bones and teeth. In the Museum attached to the hospital at Vienna, there is a large ovarium, the inner surface of which is covered with hair. Horstius met with an ovarium, containing hair, purulent-looking and oily matter. Opera, p. 249. Schenkius met with fat and hair, p. 556, and Schacher relates a simi- lar case in Haller's Disp. Med. Tom. IV. p. 477. Ruysch, in his Adversaria, says, he met with bones and hair, and Le Rich, in the Hist, de l'Acad. de Sciences, 1743, met with hair and oil, in cells, together with bones and teeth. See also Recueil Period. Tome XVB. p. 462. NOTE 87, p. 114.—Duverney saw a tumour extirpated from the scrotum, containing fleshy matter and bones. CEuvres, Tom. II p. 562. And M. Dupuy- tren presented a report to the Medical School at Paris, relating the history of a tumour found in the abdomen of a boy, containing a mass of hair, and a foetus nearly ossified. It was supposed, that at conception, one germ had got with- in another. See Edin. Med. Jour. Vol. I. p. 376. From the respectable evidence of Baudelocque, Le Roy, &c. this cannot be placed on a footing with Halley's case of a greyhound dog, who voided by the anus a hving whelp ! Phil. Trans. Vol. XIX. p. 316. I beheve that bones, hair, &c. have been found in a gelding. NOTE 88, p. 114.—Schlencker mentions a woman, who, soon after deli- very, felt obtuse pains in the left side, and presently a swelling appeared in the belly. She had bad appetite, swelled feet prolapsed uterus, and sup- pression of urine and fxces. The left ovarium was hard and stony, and weighed 3 ounces. Haller, Disp Med. Tom. IV. p. 419. In this case the tume< faction of the belly could not be caused by the presence of the ovarium, but rather by the pressure on the intestines. NOTE 89, p. 114—Vide case by Fontaine, in Haller, Disp. Med. Tom. IV. p. 485. The patient had tumour of the abdomen, with lancing pains in the left side, extending to the thigh. The left ovarium weighed 10 pounds, the right was as large as the fist, and both consisted of fatty matter. Portal likewise relates a case of this disease, where the right ovarium was as large as a man's head, very hard, and filled with steatomatous matter, weighing altogether 35 pounds. The uterus and bladder were turned to the left side. No water was effused, but the person was cut off" by hectic and diarrhoea. Some steatomatous concretions were found in the lungs. Cours d'Anatomie, Tom. V. p. 549. CHAP. xn. NOTE 1. §. 1. p. 121.—Although hysteria be not a diseased state of men- struation, yet as it is a very general attendant upon deviations of that action, and a very frequent and distressing complaint to which women are subject, it willbe properto notice it briefly at this time. 321 In the well marked hystei'ic paroxysm, a sense of pain or fulness is felt in some part of the abdomen, most frequently about the umbilical region, or in the left side, betwixt that and the stomach. This gradually spreads, and the sensation of a ball is felt passing along. It mounts upwards, and by degrees reaches the throat, and impedes respiration, so as to give the feeling of a globe in the oesophagus, obstructing the passage of the air, and, as Van Swieten observes, the throat appears sometimes really to be distended. The patient now falls down convulsed, and apparently much distressed in breath- ing, uttering occasionally shrieks, something hke the crowing of a cock, or sobbing violently, or otherwise indicating a spasm of the muscles of respi- ration. She is generally pale, and frequently insensible, at least during part of the fit, and seems to be in a faint; but when she recovers, she is con- scious not only of having been ill, but of many things which passed in a state of apparent insensibility. After remaining for some time in a state of considerable agitation of the muscular organs, the affection abates, and the patient remains langiud and feeble, but gradually recovers, and presently is restored to her usual health. This restoration is accompanied with eructa- tion, which indeed often takes place during the paroxysm; and also by the discharge of limpid urine, which, by Sydenham, is considered as a pathogno- monic symptom of hysteria. Head-ache is also apt to follow a fit. Besides producing these regular paroxysms, hysteria still more frequently occasions many distressing sensations, which are so various, as not to admit of description. Of this kind are violent head-ache, affecting only a small part of the head, sudden spasms of the bowels, dyspnoea, with or without an ap- pearance of croup, and sometimes attended with a barking cough, irregular chills, and sudden flushings of heat, spasmodic pains, palpitation, syncope, &c. These, if severe, or frequently repeated, are generally attended with a timid or desponding state of mind. During an hysteric fit, the patient is to be laid in an easy posture, a free admission of cool air is to be procured, the face is to be sprinkled with cold vinegar or Hungary water, volatile salts are to be held to the nostrils, and if she can swallow, 30 drops of tincture of opium are to be administered, with the same or a greater quantity of ether, in some carminative water; or should there be a tendency to syncope, a drachm of the spiritus ammonix aroma- ticus may be conjoined. A similar combination of opium is the most powerful remedy in the differ- ent hysterical affections above enumerated. But it is further useful to re- mark, 1st, that local pain is frequently removed by sinapisms, with or with- out the internal use of opium; 2d, that severe affections of the organs of re- spiration sometimes yield more speedily to emetics than to antispasmodics, or may even require the use of the lancet, but this mode of evacuation is to be avoided as much as possible, as it increases a disposition to the disease; 3d, that irregular action of the heart, besides requiring powerful antispasmo- dics, demands, more than any other symptom, during the attack, a state of rest, and the removal of every thing which can agitate the mind; 4th, con- tinued insensibility, or coma* is a very dangerous symptom, as it may end VOL. I. T T 3£2 fatally; the lancet ought to be early, but not largely used, the bowels should be emptied, and the head covered with a blister. The prevention of regular hysteric fits, or of individual symptoms, is to be attempted by a tonic plan, especially by the use of the cold bath, moderate exercise, preserving a correct state of the bowels, or even giving pretty power- ful purges, and the administration of preparations of steel; the mind ought also to be called as much as possible from brooding over the disease; for in hysteria, the patient is frequently desponding, and anticipating many evils. The menstrual action, if irregular, must, if possible, be rectified by appro- priate remedies. The diet should be hght, and rather sparing, and all causes of debility must be avoided. If particular symptoms should be frequently repeated, or the fits occur often, it may be useful to conjoin along with this plan, the exhibition of some antispasmodic medicine, such as valerian, assafoetida, or camphor. Hysteria may occur during the course of other diseases, or in the stage of convalescence from them. In the first case, it may cause some deviation from the regular progress or train of symptoms of the disease, and, it is to be feared sometimes calls the attention of the practitioner from more serious parts of the patient's malady. CHAP. XV. NOTE 1, p. 160.—In the eg'gs of fowls, we observe the following circum- stances. 1st, Upon removing the porous shell, we find the albumen inclosed in a membrane, consisting of two layers, and called sacciform by Levielle. These are separated from each other at .the large end of the shell, so as to form a small sac, called the folliculus aeris. The albumen is divided into three strata; the first, or cortical, is most liquid; the second, or middle, is more abundant, and thicker than the first, but less so than the third or central. The middle and central strata are inclosed in a delicate membrane, called leucilyme by Levielle, which separates them from the corticle. 2d, Within the albumen we have the vitellus or yolk, which is inclosed in a vascular membrane, called chlorilyme, or membrana vitelli, which again is enveloped by a membrane common to it and the intestines of the chick, called entro- chlorilyme. 3d, To each end of the vitellus, we have connected a portion of the central albumen, called chalaza; and in each of these a membranous sub- stance is discovered, attached to the membrane of the vitellus, and a vascular structure, which can absorb the albumen into the vitellus, to contribute to the nutrition of the chick. 4th, Upon the vitellus, we observe the cicatriculn, or small sac, called by Harvey the eye of the egg, and which was supposed to contain the foetus, the rudiments of which are allowed by Malpighi, Haller, and Spallanzani, to be pre-existent to fecundation. This cicatricula was con- „ sidered as analogous to the amnion, and supposed to contain a transparent fluid, called by Harvey colliquamentum candidum, or liquor amnii. More modern observations ascertain that the embryo is not formed in the cicatri- cula, but very near it on the vitelms, and tliat the amnion inclosirtg it, can at 823 first scarcely be distinguished from the embryo. The cicatricula soon dis- appears. Harvey's account must therefore be transferred to amnion. 5th, During incubation, the vitellus becomes specifically lighter than the albumen, and rises toward the folliculus aeris. Two arteries and two veins go from the messeraic and hypogastric vessels of the foetus, to the membrane of the yolk, and are supposed to absorb the vitellus, which therefore is carried to the vena portx of tiie chick, and nourishes the foetus. There is also a con- nection betwixt the intestines and vitelline membrane, by means of a liga- mentous substance, which was supposed by Haller and Vicq. D'azyr to be a tube, and called vitello-intestinal canal, for it is said that air has been passed through it. It was supposed to absorb the yolk, by many villi on the inner surface of the vitelline membrane ; but these are said by Levielle" not to be vessels, but soft lamellated plates. At the end of the second day, red blood is observed on the membrana vitelli. A series of dots are formed, which are converted first into grooves, and then into vessels, which go to the foetus. This appearance has been called figura venosa, and the marginal vessel vena terminahs. 6th, The vitello-intestinal ligament, and these vessels, form an umbilical cord. But besides these, we find, after the fourth day, a vascular membrane at the umbilicus, called membrana umbilicalis, which rapidly in- creases, and comes presently to cover the inner surface of the membrane of the shell. It is the chorion, and has numerous vessels ramifying on it, like the chorion of the sow, and connected in like manner with the foetus. The blood of the umbilical artery is dark-coloured, that of the vein bright. 7th, As incubation advances, the amnion enlarges, and comes in contact every where with the chorion. The albumen is all consumed, being taken into the vitellus, which is in a great measure absorbed; and what remains is taken, together with the sac, into the abdomen of the cluck, and the parietes close over it. On the 21st day, the chick breaks the shell and escapes. By in- creasing or diminishing the temperature within a certain extent, the process may be somewhat accelerated or retarded. The eggs of large birds require a longer time to be hatched; those of the ostrich, for example, take six weeks. Hence it appears, that the vitellus and albumen contribute to the increment of the foetus, whilst the exterior membranes act as lungs, the air being trans- mitted through the pores of the shell. The eggs of fishes have a general resemblance to those of fowls, and con. sist of a vitellus and albumen, with their membranes; but in place of being furnished with a shell, they have a tough, or sometimes a horny covering, and some, as those of the shark, torpedo, &c. are quadrangular in shape. The yolk is connected to the intestines of the foetus, and its membrane is very vascular. As in fowls, so in fishes, it is ultimately inclosed within the abdo- men of the young. In the skate, numerous blood vessels are formed in the albumen, which supply the place of gills, and are supposed by Dr. Monro, to be afterwards covered and converted into gills. The two functions of a placenta, then, are still more distinctly fulfilled here than even in fowls, for the apparatus for nutrition and respiration has different or distinct termina- SM tions; whereas in fowls and quadrupeds, all the vessels enter at one place. A similar fact is observed in the ova of frogs, for the umbilical cord in the 4 tadpole goes to the head. The egg of the serpent is nearly the same with that of the fish, and is in- closed in a flexible membrane. The foetus is coiled up spirally within it, and the chorion is vascular, as in the egg of the fowl. The adder is a viviparous animal; its uterus is membranous, and divided, I find, into eight or nine cells, each of which, in September, contains an ovum as large as a chesnut. This consists of an exterior membrane, which incloses a foetus about six inches long, and coiled up. About an inch from the tail, the umbilical cord passes out, which consists of vessels that go to ramify on the exterior membrane, which resembles the chorion of the sow. There is also a connection with a vitellus, which is as large as a hazel nut. The coluber natrix is said, by Valmont-Bomare, to have a placenta and cord within the egg, but this is contrary to the general structure of eggs; most likely the chorion has been taken for the placenta. The eggs of reptiles are often deposited in packets, the eggs being g-lued together. The egg of the turtle is as large as a lien's, and is inclosed in a covering like parchment It is deposited in the sand, and is hatched in about 24 days. The egg of the alligator is similar in structure to that of the turtle ; it is rather larger than a goose's egg, and covered with a thin skin, so transparent, how- ever, that the foetus may be seen through it. Those animals which are called oviparous hatch their eggs out of the body either by sitting on them as we see in fowls, or by exposing them to the heat of the sun, as the turtle, crocodile, and many serpents. Oviparous fishes, which comprehend all those called osseous, expel their ova into the water, where they are fecundated by the male, but without copulation. Many fishes leave the sea, and come up the rivers to spawn. Others remain in the ocean; and the eggs, specifically lighter than the water, float on the surface. Many fishes attach them to marine plants, and in some cases the ova are fixed to the body of the parent. The ova are covered with a kind of mucus, which has been supposed to defend them from the water. The ova of frogs, &c. are likewise fecundated and hatched out of the body. They are enveloped in a glary matter, which perhaps contributes to their increase; for during incubation, the egg both enlarges and changes its shape. Those animals which hatch their eggs within the body are called ovo- viviparous, such as cartilaginous fishes, as the shark, skate, and torpedo, &c. The scorpion and venomous serpents also belong to this class. Ovo-viviparous animals expel the young fully formed, and therefore have been sometimes considered as having uteri hke quadrupeds, and a cord attached directly to it. SpaUanzani at first supposed that the foetus of the torpedo was attached directly to the uterus, but afterwards found that it was contained in a distinct ovum. Experiences, p. 294. See also Cuvier Lecons d'Anat. Comparee, Tom. V. p. 142. The shark is said to have an uterus like the bitch, and Belon says he saw a female dehvered of eleven young, attached by a cord. Its mode 325 of gestation most likely is similar to the torpedo. This class expel their young often very quickly. A female syngnatus hyppocampus was observed to ex- pel at least a hundred in a very short time. Analogous to ovo-viv iparous animals, are those which receive the ova into cells on the surface of the body, where they are hatched. This is well seen in the pipa, a species of toad. Even the tadpoles are said to be metamor- phosed in these cells. The opossum tribe has a modification of this gesta- tion; for in them the foetus, when very small, is expelled into a bag situated on the belly, and immediately attaches itself to a nipple. The utero-gesta- tion of the opossum of North America lasts only from 20 to 26 days, and the embryo when expelled does not exceed a grain. It remains in the sac about 50 days, and acquires the size of a mouse. In other animals, as for instance the bat, the young after birth attach themselves to the nipple, partly for the convenience of being transported or carried about. In plants, we find likewise a placenta or structure, intended for the nourisliment and respiration of the foetus. To take the kidney bean for an example, we find within the membranous covering two parenchymatous lobes, or cotyledons; and at the margin betwixt these, there is the corculum or cicatricula. During incubation, we find that this sends up a small shoot called the plumula, and down a radical into the earth. But to support the plant until the root and leaves are capable of maintaining it we find the cotyledons rise up out of the earth, on each side of the plumula, forming what are called seed leaves. These both serve for the respiratory organs, and also supply pabulum, which is absorbed by proper vessels, and in con- sequence thereof they presently are destroyed. When there are more lobes than two in the seed, there are a corresponding number of seed leaves. In many cases these cotyledons do not rise out of the ground, but the plumula alone appears. This is the case with the garden pea, but the cotyledons still perform their functions below the ground, and exist until the foliage of the plant, or adult organs, be formed. The greatest part, then, of a vegeta- ble seed or ovum, consists, like the eggs of fowls, of an apparatus intended for the nutriment and respiration of the foetus, whilst the embryo itself is very small. The cotyledon consists, in many eases, of a farinaceous sub- stance. In other seeds it is oily and farinaceous, and in some is almost all oily. Vegetable ova sometimes are contained in a dry pericarpium, and are shed into the earth when it bursts. But others have an apparatus provided, not only for their present growth, but also for accelerating their incubation in the earth. In stone fruit and nuts, we find that vessels pierce the shell at the bottom, and pass on toward the top, and reach the kernal or lobes, which are contained within the shell, enveloped in a soft membrane. They arc in- serted very near the embryo. Now, for the farther support of these parts, we find that stone fruits are covered with a quantity of nutritious matter. The almond, for example, has its ligneous nut covered with a fleshy sub- stance about an inch thick, inclosed in a proper membrane. The rhamnus lotus has the stone surrounded with farinaceous matter, which tastes like 326 gingerbread. Other seeds are contained in a parenchymatous or succulent substance, as the apple or pear, or in a firm white substance like cream or marrow, or in a mucilaginous matter as the gooseberry, or in an organized puln. as the orange and garcinia mangostona. Some are deposited in a luscious fluid at first, which ultimately becomes farinaceous, as the plantain. chap. xvn. NOTE 1, p. 169.—In Dr. Clark's case the morning sickness, and other signs of pregnancy, appeared very regularly. At the end of nine months, attempts were made to expel the foetus. These were followed by inflamma- tion and decline of health. Then suppuration took place, and the patient sunk. Transactions of a Society, &c. Vol. II. p. 1. In Mr. Mainwaring's case, in the same work, p. 287, the patient suffered much from morning sickness, and pain at the groins. NOTE 2, p. 169.—In the Journal de Scavans for 1756, we are told of a woman at Louvain, who at first had so dreadful pain when she went to stool, that she thought her bowels were coming out.—In Pouteau's case, the woman suffered great pain till after the second month. Melanges, p. 333. NOTE 3, p. 169.—Bianchi mentions a case, in which, in the first months, the woman complained of great pain in the lower belly, with nausea and fainting fits. The motion of the child ceased in the fifth month, and then milk was secreted. De Nat. in Hum. Corp. Vitioso Morbosoque Gener. p. 166.—In Dr. Mounsey's case, the pain, vomiting, and fainting fits, continued till the woman quickened. Phil. Trans. Vol. XLV. p. 131.—In Dr. Fern's case, the person complained of great pain till the third month; and from that period till the eighth month, was subject to convulsions and syncope. Phil. Trans. Vol. XXI. p; 121. NOTE 4, p. 169.—In Dr. Perfect's case, no labour pains came on, but the motion of tiie child ceased at the end of nine months. The abdomen neither increased nor diminished in size for two years and seven weeks ; but she was afflicted with constant pains in the hypogastric region, attended with fever, and finally sunk under marasmus. Cases in Midwifery, Vol. 11. p. 164. NOTE 5, p. 170.—Vide cases by Longius, in his Epistolx, Tom. II. p. 670. Tulpius Opera, lib IV. c. 39, p. 358.—Pouteau in his Melanges, p. 373.—Air. Shiever,in Phil. Trans. No. 303, p. 172.—Winthrop, Phil. Trans. Vol. XLHl. p. 304, and Simon, p. 529.—Lindestaple, Vol. XLIV. p. 617. Morley, Vol. XIX. p. 486. Gordon, in Med. Comment. Vol. XVIII. p. 323. Cammel, in Lond. Med. Jour. Vol. V. p. 96. Case by M. Bergeret, in the Recueil Pe- riodique.Tom. XIV. p. 289. NOTE 6, p. 170.—Vide Marcel. Donatus, De Med. Hist. Mirab. lib. IV. c. 22.—Horstii Opera, Tom. II. p. 536. In this case, the foetus was discharged both by the vagina and rectum.—Benevoli, in his Dissert, p. 104, gives an in- stance where the greater part of the child was expelled by the vagina, but the woman died before the process was completed.—Mr. Smith's case, in Med 327 Comment. Vol. V. p. 314.—In Mr. Colman's case, pains came on, and the head was felt in the pelvis at the time of her reckoning, and long afterwards, but the os uteri could not be perceived. In some time, hectic fever, with diarrhoea and sore mouth, appeared. Six months after her attempts at labour, an onen- ing was felt in the vagina, but very unlike the os uteri. The hand was in- troduced, and a putrid child was extracted. Some fxces continued to come by the wound, but at last she got well. Med. and Phys. Jour. Vol. II. p. 262.— See also Camper's case, in his Demonst. Anat. Path. lib. II. p. 16, and Dr. Fo- thergiU's case, in Mem. of Med. Society, Vol. VI. p. 107. NOTE 7, p. 170.—Vide Stalpart Vander Wiel, Opera, Tom. I. p. 305. In this case, bones came away with the urine.—In the case of Ronseus, the child was discharged parti} by tiie bladder, but chiefly by the anus. Epist. Med.—A similar instance is related by Morlanne, the extraneous matter forming a nucleus for a calculus. Recueil Period. Tom. XHI. p. 70.—In Prof Josephi's case, the child was found altogether in the bladder. Med. and Phys. Jour. Vol. XIV. p. 519. NOTE 8, p. 170.—Vide case of Mrs. Stag, in Lond. Med. Obs. and Inqui- ries, Vol. II. p. 369; and cases by Mr. Jacob, Dr. Maclarty, and others. NOTE 9, p. 170.—In Mr. Giffard's case, the child was expelled entire by the anus, and even the cord was found hanging out of the intestine. Phil. Trans. Vol. XXXVI. p. 435.—See also Mr. Goodsir's case, in Annals of Me- dicine, Vol. VII. p. 412. NOTE 10, p. 170.—In Dr. M'Knight's case, although the exsarean opera- tion was performed before any bad effects were produced on tiie health, no part of the placenta could be found. NOTE 11, p. 170.—In Dr. Clark's case, the tube burst in the second month, and the woman died from loss of blood. Transactions of a Society, Vol. I. p. 216.—Vide case by Duverney, in his works, Tom. II. p. 353, and by M. Littrein the Memoirs of the Acad, of Sciences, for 1702, and by Itiolan, in his works. See also Med. Comment. Vol. 1. p. 429.—In Mr. T. Blizard's case, rupture took place at a very early period, for the woman had miscar- ried only five weeks previous to this event. Vide Edin. Phil. Trans. Vol. V. p. 189.—Mr. Tucker's case, Med. and Phys. Journal, XXIX. 448. NOTE 12, p. 170.—I have known .the foetus retained for twenty years; and there are some instances, where it has been retained thirty, forty, or fifty years. Mrs. Huff, whose case is related in the Med. ainl Phys. Jour, for May 1800, carried the child fifty years. Middlcton's patient carried it sixteen years. Phil. Trans. Vol. XLIV. p. 617. Mounsay's thirteen years, Vol XLV. p. 121. Steigertahl's forty-six years, Vol. XXXI. p. 126. Broomfield's nine years, Vol. XLI. p. 696. Sir P. Skippon's patient discharged it by suppuration at the groin, after retaining it twenty years, Vol. XX1V. p. 2070. See also cases by M. Grivel, in Edin. Med. Jour. Vol. II. p. 19, and Dr. Caldwell, p. 22. Some- times no attempt is made to expel, but the foetus is converted into a sub- stance, which Fourcroy finds to resemble the gras des cimetiercs. System, Tom. X. p. 83. Sandifort relates a case, where, after attempts at labour, no further inconvenience was sustained, but the child was found after twenty- 328 two years to be indurated. Observationes, lib. II. p. 36. He quotes Ncbel for a case, where it was retained fifty-four years. Chesclden found it con- verted into earthy matter. The late Mr. Hamilton of this place had a pre- paration of a foetus, covered with calcareous matter, which was retained 32 years. This woman had pains at the end of nine months, after which the belly decreased in size. NOTE 13, p. 170.—In the 5th Vol. of the Edin. Med. Essays, there is re- lated a case, in which the patient seemed to have a second extra-uterine pregnancy before she got quit of the first.—See also Primrose de Morb. Mul. p. 326.—Mr. Hope, in the 6th Vol. of the Med. and Phys. Jour. p. 360, details a case, where the woman in the seventh month of pregnancy had pains, which continued for three weeks, and then went off, leaving a hard tumour on the left side, which was somewhat painful; she then had another pregnancy, and a fortnight after delivery, began, after taking a laxative, to vomit, and continued to do so, ultimately throwing up feculent matter. The case ended fatally.—See also Turk, in Haller, Disp. Chir. IV. 793. NOTE 14, p. 170.—In Mr. White's case, related in Med. Comment. Vol. XX. p. 254, the symptoms were very hke those of retroversion, and the case was only distinguished by the result. In Mr. Cammel's case, there was not only a tumour betwixt the vagina and rectum, but the os uteri was turned upward and forward. Lond. Med. Jour. Vol. V. p. 96. Mr. Kelson's case very much resembled retroversion, for in the tenth week both the urine and stools were obstructed. In about a fortnight, the impediment was suddenly re- moved, and the uterus felt in situ. She continued well till the ninth month, when labour ineffectually came on; but in process of time, tiie child was discharged by the anus. Med. and Phys. Jour. Vol. XL p. 293. NOTE 15, p. 171.—Boehmerlongagoobservedthis; and Dr. Baillie, in the 79th Vol. of the Phil. Trans, mentions, that Dr. Hunter had a preparation of tubal pregnancy, in which the uterus was found enlarged to double its na- tural size, and containing decidua. He also states, that in an ovarian case, the uterus was enlarged, thick, and spongy, and its vessels enlarged. Dr. Clarke found the uterus, in the second month of an extra-uterine pregnancy, exactly of the same size as if the embryo had been lodged within it. The decidua was formed, and the cervix filled with gelatinous matter. Trans- actions of a Society, Vol. I. p. 216. See also a case by Saviard, in Phil. Trans. No. 222, p. 314. A case, similar to Dr. Clarke's is related by Mr. T. Blizard, in the Edin. Phil. Trans. Vol. V. p. 189. See also Annals of Med. Vol.111, p. 379. NOTE 16, p. 171.—In Mr. Houston's case, the cervix was so closed up that it would not admit a probe. Phil. Trans. Vol. XXXH. p. 387. The decidua woukl appear sometimes to enlarge, and form a mass like placenta, which in Mr. Turnbull's case was expelled with hemorrhage. Mem. of Med. So- ciety, Vol. m. p. 176. NOTE 17, p. 171.—In a case related by Varocquier, the ovarium did not acquire a larger size than an egg. The woman died, after suffering violent pain in the left side, low down. The viscera were slightly inflamed. Mem. 329 de l'Acad. de Sciences, Tom. CXI1I, p. 76. In the case by L'Eveille, the foetus was apparently betwixt three and four months old. Rapport de la Societe" Philomatique, Tom. I. p. 146. See also a case in the Recueil Period. Tom. XIII. p. 63; and in the Recueil des Actes de la Societe de Lyon NOTE 18, p. 171.—Vide Chambon, Malad. de la Grossesse, Tom II. p. ?>73. Case by St. Maurice, in Plul. Trans. No. 150, p. 285. In the case re- lated by La Rocque, the ovarium was found ruptured, and the abdomen full of blood. Journ. de Med 1683. Boehmer found the ovarium ruptured, and the foetus half expelled. Obs. Anat. fuse. prim. Dr. Forrestier's patient, after violent colic pains, voided blood by the anus. The hemorrhage and fainting fits proved fatal. The foetus was found in the ovarium. Annals of Medicine, Vol. III. p. 379. NOTE 19, p. 171.—Vide Roederer, Elemens, c. 15. §. 758. In Air. Dumas' case, a fluid like chocolate was drawn off by tapping, which was twice per- formed. The ovarium contained hair, bones, &c. La Med Eclaree, Tom. IV. p. 65. Mr. Bell's tubal case excited ascites. NOTE 20, p. 172.—Vide Dr. Kelly's case, in Aled. Obs. and Inquiries, Vol. IH. p. 44. In Mr. Clarke's case, the placenta was attached to the kidneys and intestines. Mem of Med. Society, Vol. III. p. 197. In the Mem. of the Acad, of Sciences, there is a case related, where the placenta adhered to the lumbar vertebrx. In the history by La Coste, it was placed under the stomach and colon. Vide CEuvres de Duvemey, Tom. II. p S63. In Mr. Turnbull's case, it was very thin, and adhered to the intestines. Mem. of Aled. Society, Arol. III. p. 176. A case of ventral pregnancy, complicated with hernia, is related by M. Martin in the Recueil des Actes de la Societe de Sante de Lyon. Courtial found it adhering to the stomach and colon. NOTE 21, p. 173.—Dr. Maclarty relates the case of a negress, where the breech of the child protruded through an ulcer, at the lower part of the abdominal tumour, and the arm at the upper part of the tumour. The in- termediate portion of skin was divided, and the fcetus extracted. The head of the child stuck firmly, but was brought out with the forceps. There was no placenta, but putrid matter was discharged with the child. The woman, recovered. Med. Comment. Vol. XVII. p. 481. Another case is related by Duvemey, where the child was extracted from the groin; and this is one of the rare instances where the placenta was not destroyed. It was ex- tracted with the child. CEuvres, Tom II. p. 357. Cyprianus gives an inr stance of the child being removed, after having been retained twenty-one months. Histor. Fcetus Hum. Salva Matre, ex Tuba F.\cibi. Mr Brodie en- larged the navel with a lancet. Phil. Trans. Vol. XIX. p. 580. See also M. Baynham's case, in Med. Pacts, Vol. I. p. 73. In Mr. Bell's case an inci- sion four inches in length was made, and the bones of two children extracted. Med. Comment. Vol.11, p. 72. Dr. Haighton relates an interesting case, where some bones were discharged by the vagina, but the tumour also pointed above the pubis, and through this one of the ribs appeared. The practitioner made an incision, but so great hemorrhage came on, that he VOL. I. U t 330 was obliged to apply a bandage till next day, when he extracted the bones The woman recovered. Med. Records, p. 260. Dr. M'Knight performed the operation in the twenty-second month, although the woman enjoyed tolerable health; very dangerous symptoms supervened, but the woman, who certainly was brought into a very hazardous state by the premature operation, did recover. No placenta was found. Mem. of Med. Society, Vol. IV. p. 342. NOTE 22, p. 173.—In Dr. Morley's- case, this happened two years after the original abscess had healed. Phil. Trans. Vol. XIX. p. 486. Mr. Moylc details a history, where the abscess first of all burst, in consequence of leap- ing over a hedge. Bones continued to be discharged for a year, without much injury to the health. The abscess then healed, but three years after- wards a tumour again appeared, and, in consequence of exertion, burst; when about a yard of intestine protruded. Some days elapsed before Mr. Moyle saw her. The intestine was then gangrenous, but she lived 12 days longer, and the portion was thrown off before death. Med. Jour. Vol. VI. p. 52. CHAPTER XIX. NOTE 1, p. 207.—Air. Pearson relates a case, where the uterus was re- troverted, in consequence of being scirrhous. A ide Pearson on Cancer, p. 113. Dr. Marcet gives an instance where the uterus was retroverted, with- out pregnancy, producing constipation and vomituig. Vide Cooper on her- nia, part II. p. 60. NOTE 2, p. 207.—AI. Baudelocque relates a case, where the fundus uteri protruded at the os externum, the patient at the same time having violent inchnation to expel something. He was, however, able speedily to reduce the womb to the^proper state. Vide l'Art, &c. §. 125. In Dr. Bell's case, a portion of the rectum was protruded by the uterus. Med. Facts, Vol. VJH. p. 32. NOTE 3, p. 208.—AI. Baudelocque gives a case of this kind, §. 253. In Dr. Bell's case, as the woman complained for five weeks of dysuria only, it is likely, that for that period the retroversion was not complete. Med. Facts, Vol. VIII, p. 32. Dr. Hunter supposed that it might take place in various degrees; it might be complete, or semi-complete, or even the os uteri might remain in its natural situation. He says, that Dr. Combe and he saw a case, where the os uteri was pushing out as in a procidentia; but this, perhaps, will not be admitted to have been retroversion. Med. Obs. and Inq. Vol. V. p. 388. In the same volume, p. 382, Dr. Garthshore relates an instance of semi-retroversion. NOTE 4, p. 208.—In the case described by Dr. Hunter, Med. Obs. and Inq. Vol. IV. p. 400, the bladder after death was found to be amazingly dis- tended, but not ruptured. NOTE 5, p. 208.—In Mr. Lynn's case, the bladder burst, and immediately afterwards the woman miscarried, but the uterus after death was found to be still displaced. Med. Obs. and Inq. Vol. V. p. 388. Dr. Squire relates an instance in which the bladder also gave way. Med. Review for 1801. 331 NOTE 6, p. 208.—In Mr. Wilmer's case, the belly was greatly distended; six pints of urine were drawn off, but the woman soon died. On inspecting the body, the bladder, from the disease of its surface, was found to contain a quantity of coagulated blood, and the inflammation had spread to the colon. In this case, the umbilicus was protruded hke half a melon, and the disease was at one time taken for hernia. The uterus was found to be so firmly wedged in the pelvis, that it could not be raised up till the symphysis pubis was sawed away. "Wilmer's Cases, p. 284. NOTE 7, p. 208.—In Dr. Ross's patient, after the uterus was reduced, abor- tion took place; and the woman dying, the bladder was found tobe thickened, and adhering to the navel. Annals of Medicine, Vol. IV. p. 284. NOTE 8, p. 209.—This is illustrated by Dr. Garthshore's patient who, notwithstanding these symptoms, ultimately did well. After the reduction of the womb she miscarried, and foetid lumps were for some time discharged from the bladder. Med. Obs. and Inq. Vol. V. p. 382. NOTE 9, p. 209.—In Mr. Croft's case, the disease was of a month's stand- ing, the woman was oedematous, and she was supposed' to have dropsy ; but by introducing the catheter, seven quarts of urine were drawn off. The in- troduction was daily repeated for some time, and then occasionally, as cir- cumstances required, for three weeks. The swelling of the legs went off, and the uterus gradually rose. Med. Jour. Vol. XI. p. 381. NOTE 10, p. 209.—A case is related by Air. Ford, in which the catheter being allowed to slip into the bladder, produced a sinuous ulcer. Med. Facts, Vol. I p. 96. NOTE 11, p. 209.—In Air. Cooper's case, whenever the tumour was pressed back, the woman called out that she could now make water. Med. Obs. and Inq. Vol. V. p. 104. NOTE 12. p. 209.—This was done by Dr. Cheston. The woman remained long very ill, but she carried her child to the full time, and recovered. Aled. Commun. Vol. II. p. 96. In one instance, by using a long trocar, the uterus was wounded, and the woman died. NOTE 13, p. 210.—Dr. Hunter mentions a case, in which the uterus re- covered itself immediately after the bladder was emptied. Med. Obs. Vol. IV. p. 408. And in Mr. Croft's second case, the water having been drawn off for six days, the uterus suddenly rose. Lond. Med. Jour. Vol. XI. p. 384. NOTE 14, p. 211.—Both Dr. Ross's patient and Dr. Cheston's patient, the latter of whom recovered, complained of uneasiness in the throat which Dr. C. considers as a mark of slow peritoneal inflammation. NOTE 15, p. 211.—This circumstance has been mentioned by different writers, and a distinct case is related by Mr. Merriman, in the Med. and Phys. Jour. Vol. XVI. p. 388. Mrs. F. being about five months pregnant, was suddenly terrified, and felt as if her inside were turned upside down. The symptoms, however, were not very acute, for she voided the urine in the last month of gestation, though with pain and some difficulty. On the 16th of June, she had some pains, and a discharge of serous fluid; no os uteri could be felt, but a large semi-globular tumour at the back part of the vagina, bearing down toward the perinxum. The pains brought on fever, 332 and at last delirium and convulsions. She was bled, and had a clyster, after which 3he got some sleep, and the pains continued moderate, though regu- lar, for (wo or three days, and she passed both urine and stools. On the 20th, nothing like os uteri could be felt; but on the 21st, there was perceived a thick ffattened fleshy substance descending into the vagina, and very soon the uterus was restored to its natural situation The substance was found to be the scalp of the child, containing loose bones. The child and placenta were dehvered, and the mother recovered. NOTE 16, p. J13.—In Mr. Bird's case, the accident succeeded to stooping, in washing clothes. Med. Obs. and Inq. Vol. V. p. 1U0. In Mr. Hooper's case, the woman was frightened by an ox, and in attempting to escape, fell down, after which the svmptoms appeared. Mr. Evan's patient ascribed it to lifting a burden. Aled. Comment. Vol. VI p. 215; and Air. Swan's patient to a fall, p. 217. Air. Alerriman's patient first complained after being sud- denly terrified; and Mr Wilmer's patient had the uterus retroverted, after being fatigued with weeding. NOTE 17, p. 214.—Vide Chambon, Malad. de la Grossesse, p. 16. M. "Bn.cdelocque relates a case from the practice of Choppart, where it was pro- duced in the second month of pregnancy, by the action of an emetic. L'Art, &c. § 255. NOTE 18, p. 214.—Sometimes the hemorrhage proves fatal. A singular case is to be met with in the Medical Pacts, Vol. 111. p. 171, by Canestrini, where the woman had a double uterus. One of the uteri, after some pains, 'Xit v*burst in the fourth month. The ovum was found entire in the abdomen, and much btood was effused. NOTE 19, p. 214.—A twin case is related by Dr. J. Hamilton, where the uterus was so thin, that even the sutures of the head could be felt through the abdominal parietes. Violent pains were produced by the motion of the child, the uterus felt very light, and the woman had been exposed to a de- gree of violence. This case had a very considerable resemblance, in some respects, to a ruptured uterus, but she was delivered safely of two children. H^Cases, p. 124. *?**. ! NOTE 2 J, p. 214.—Sometimes the tumour rather increases. In Dr. Per- cival's cas; , the belly becanu much larger after the accident, and continued so for about a year. Then it subsided all m once, when the woman was in a recumbent posture. Med. Comment. Vol. II. p. 77. NOTE 21, p. 214.—Dr. Drake's case, where the uterus seemed to burst in '■V /the fourth month,- terminated by suppuration at the navel. Excrement was EfiF for some time discharged at the opening. Phil. Trans. Vol. XLV. p. 121.— A washerwoman at Brest had the uterus ruptured by a fail in the seventh month, and ultimately expelled the foetus at the navel Mem. of Acad, of Sciences for 1709.—Guillerm, in tiie same work for 1746, mentions a woman who had the womb ruptured by a fall in the sixth month. She immediately ;.■' , fainted, and a discharge took place from the vagina. The child was expelled by the anus.—See also the cases by Dr. Percival, Mr. Wilson, &c. NOTE 22, p. 215.—In the Journ. de Aled. for 1780, there is a case of a woman, who had tiie uterus ruptured in the fourth month of pregnancy. The ooo accident was followed by uterine hemorrhage, which continued for some time. The menses returned, but the belly did not subside. In the ninth month she died. The uterus was found of the natural size, but the rent was still perceptible. The uterus for some time does not return to its unimpregnated state, as is evident from the following case, which 1 lately saw. Anne Neilson, aged 24 years, fell on the ground about a month ago, being then in the ninth month of her first pregnancy. She felt at the time as if something had burst near the navel, and perceived more fluttering of the child than usual. This continued in a certain degree for two days, after which, she felt no more motion. In the course of two or three days after the accident, she was seized with irregular pains, chiefly about the belly, and these are rather increasing than diminishing in severity. The belly has subsided considerably in size,______ is hard, particularly above the navel, toward the stomach. The umbilicj^^H itself, is soft and prominent. The bowels are regular, urine proper, tongue clean, heat natural, pulse 84, has occasional shivering. On examining, per vaginam, the lower part of the uterus is felt soft and tubulated, very unlike either the gravid or unimpregnated womb. It hangs into the vagina, like a fleshy inverted cone. By some degree of attention the os uteri is discover- ed at the lower part, or rather a little backward. It has no distinct project- ing lips as in the unimpregnated state, but by pressure with the finger, the aperture is felt with thin margins, and the point of the finger may be in- troduced a very little way within it. The head of the child is discovered between the uterus and pubis. No distinct member can be felt through the abdominal parietes. Dr. Jeff'ray possesses a preparation of a foetus contained in a kind of cyst taken from a woman who had carried the child above 20 years : the rupture was occasioned by a fall. NOTE 23, p. 215.—In the Journal de Aled. for 1780, a case is detailed of a woman, who, in the month of January, being then seven months pregnant, was squeezed betwixt the wall and a carriage, and had the uterus ruptured. She instantly felt violent pain in the belly, and a discharge took place, from the vagina, which continued in variable quantity for. six weeks. The strength gradually sunk, and in June she began to vomit, and continued to do so for several days, when she died. The abdomen was found inflamed, and con- tained the remains of a putrid child. The rent was visible in the womb. NOTE 24, p. 215.—In Air. Wilson's patient, the accident was produced by being kicked. She complained of pains all night after the injury, and next day had a sanguineous discharge from the vagina, and soon afterwards was attacked with violent griping pain. The foetus was ultimately discharged by an abscess, bursting externally. Annals of Med. Vol. II. p. 317, and Vol. IV. p. 401.—Dr. Garthshore's patient ascribed it to violent exercise. Med. 4 *; Journal, Vol. VIII. p. 334—Air. Goodsir's patient to exertion. Annals of Med. Vol. VII. p. 412.—In the 5th and 6th volume of the Journal de Med. are two cases, the first produced by a fall from a tree, the second by a brui«e from a waggon. Other instances, if necessary, might be added. * W I 1 pr •<—*>g*-- ^t^fll *V '**4£'