HEADACHES FROM NASAL CAUSES. BY SARGENT F. SNOW, M.D., OF SYRACUSE, N. Y.J AURIST AND LARYNGOLOGIST TO THE HOUSE OF THE GOOD SHEPHERD, SHELTER FOR HOMELESS WOMEN, AND TO THE SYRACUSE FREE DISPENSARY. FROM THE MEDICAL NEWS, July IO, 1897. [Reprinted from The Medical News, July 10, 1897.] HEADACHES FROM NASAL CAUSES.1 By SARGENT F. SNOW, M.D., OF SYRACUSE, N. Y. ; AURIST AND LARYNGOLOGIST TO THE HOUSE OF THE GOOD SHEPHERD, SHELTER FOR HOMELESS WOMEN, AND TO THE SYRACUSE FREE DISPENSARY. In this paper I do not intend to dwell to any ex- tent on the history of individual cases but to give a sort of abstract of experience, selecting as a basis for conclusions only representative cases which have been followed up carefully, a table of which is appended. Neither will I include those headaches associated with inflammatory disease of the accessory cavities, this latter affection having been so comprehensively written up during the past three years. In a paper on " Hemicrania " 2 I have called at- tention to pressures within the noseas a cause of sick headaches and neuralgic affections. At that time it was felt that perhaps an apology was due for ventur- ing on a subject so nearly barren of literature. Now I am pleased to find that others both here and abroad are giving the nasal passages due credit. As early as 1886 Dr. Harrison Allen of Philadelphia published a paper on " Headaches Associated Clinically with Chronic Nasal Catarrh."3 The essay was compre- hensive, replete with valuable deductions, and with- out doubt was the first published on the relation of headaches to intranasal conditions. In a foot-note 1 Read before the American Laryngological, Rhinological, and Otological Society, Washington, D.C., May i, 1897. 2 New York Medical Journal, March 31, 1894. 3 The Medical News, March 13, 1886. 2 he mentions a discussion touching on this subject which took place at the New York Academy of Med- icine, January 21, 1886, but after his paper was writ- ten. In 1888 Dr. JohnO. Roe contributed a paper, entitled " The Frequent Dependence of Persistent and So-called Congestive Headaches upon Abnormal Conditions of the Nasal Passages." 1 Aside from these, and the mention made of the nose as a factor by Dr. Wharton Sinkler in an excellent article on the " Etiology and Treatment of Migrain " 2 I have been unable to find record of any paper relating to this subject by American writers until that produced by myself in 1893. From all data at command, I think Dr. Hack of Freiburg (quoted by Sinkler) was the pioneer in Europe in recognizing the fact that headaches some- times come from nasal causes. Maximilian Bresgen of Frankfurt wrote a paper on " The Headaches in Nose and Throat Diseases," 3 a copy of which he has courteously sent me. This article is very clear and concise, pointing out with detail the regions which most commonly produce headaches, and their great frequency as a symptom in nose and throat diseases. At a meeting of the British Laryngological Associa- tion, held in London, October 12, 1894, Mayo Col- lier reported a case of '' Headache from a Diseased Middle Turbinal. " Dr. J. H. McCassy of Dayton, Ohio,4 in connection with his experience as superin- tendent of the Kansas State Insane Asylum, says: " As might be expected, headache is alarmingly 1 Medical Record, August 25, 1888. 2 The Medical News, July 19, 1890. 3 Munch. Med. Woch., January 5, 189}. 4 Cincinnati Lancet-Clinic, Septembers, 1896. 3 common among the insane. I am convinced that hypertrophies, vasomotor rhinitis, polypoids, de- flections of the septum, catarrh of the ethmoidal, frontal, and maxillary sinuses, etc., are frequently causes of headaches, and in not a few cases of in- sanity. ' ' For a number of years past the neurologist and the ophthalmologist have had full sway in the treatment of these cases. They have published many valuable books and papers and should receive due credit. One of the recent productions is Corning's on " Headaches and Neuralgia. ' ' The author does not even speak of a possible nasal cause in his classifica- tions, though he mentions at considerable length those termed nervous, toxic, bilious, etc. Errors of refraction must, of course, be corrected, but the rhinologist should have a place in this line of work. I have selected from my records thirty cases of ceph- alalgia that have been referred to me as a last resort by different physicians. These patients on examina- tion appeared to be fit subjects to work upon and treatment was instituted. They do not include those met with in any hospital or dispensary prac- tice, or those who have been mentioned inciden- tally during the course of ear or throat treatment, where nasal surgery has been a prominent feature, and by means of which their headaches had been cured. In this group of thirty patients I find that seven claim to have received relief to the extent of about 40 per cent., five 75 per cent., ten 90 per cent., and eight 100 per cent. A careful review and study of their records bring out some interesting points. Sixteen were treated be- 4 tween 1891 and 1894, giving from three to five years in which to judge of results. Ten of these show from 90 to 100 per cent, relief of their head- aches. Twenty of the thirty cases were females. The youngest was seventeen and the oldest sixty-five years of age. Sixty per cent, of the whole number were from thirty to forty years of age. Seventy per cent, of these patients appeared to have hemicrania as a result of middle turbinate pressure. Of those reported as showing 100 per cent, relief, the whole number, eight, received a full and thorough operative course. Fourteen, because of their improved condi- tion, stopped treatment before all the visible intra- nasal contacts and pressures were removed. The remaining eight had a complete operative course, but owing to the sensitive condition of their mem- branes they are yet having some headaches, though four are found in the 90-per-cent. class. Another notable fact deduced from these thirty cases is that of the sixteen who received a full operative course, twelve report from 90 to 100 per cent, improve- ment. Experience with other cases not mentioned in this list teaches me that about the same ratio of improvement (75 per cent.) will hold good in all headaches from nasal causes, if each and every point of pressure or contact is thoroughly removed. Oper- ative work on these patients is what gives quickest and most brilliant results. It should be carried out with the fact in mind that the nasal membranes are very sensitive and prone to swell, and a little more of the offending overgrowth than is necessary to abso- lutely relieve the pressure should be removed, though 5 not enough to impair the natural function of the nose. Hajek of Vienna attributes the headaches so com- monly met with after tamponing the nose and in acute coryza to a stasis. His opinion is that the veins passing through the lamina cribrosa give off one large branch to the dura mater, turn, and again enter the nasal cavities; these become engorged, press against the brain substance, and occasion severe pain. Schreck of Munich looks upon hemicrania, due to nasal and postnasal causes, as partly attrib- utable to the hindered flow of lymph and venous blood from the brain. Dr. Robert C. Myles of New York writes me that in his opinion " vasomotor dis- turbances of this region or compression of the small nerves in the bony canals of the cribriform plate by the artery or vein will cause headaches under certain conditions." This theory of stasis produced by a retarded circulation, coming as it does from three eminent and independent sources, should receive consideration. Perhaps it will explain why some twenty-five per cent, of our patients have an oc- casional return of their trouble after all visible pres- sures and contacts have been removed. According to some neurologists, it may be due to the fact that " all influences exerted upon the human body are to a greater or lesser degree cumulative, and the phe- nomena following these are proportionate to the re- sponse yielded by the receiving nerve-centers." Personally, I think that most of these recurring at- tacks are produced by the irritable and sensitive condition of the membranes, which favor congestion with resulting pressure on sensitive areas. 6 In those cases of headaches from nasal causes which have come under my observation, but two can be recalled in which the patients at the time of their seizures did not show some point or points of contact within the nasal fossae. Their relapses may be due to stasis as mentioned above. It has been noticed that they as well as others are kept very comfortable if weekly or biweekly stimulating applications be made in order to keep the relaxed and sensitive membranes in proper tone. The treatment that ap- pears to act best in producing this result is a gentle spraying of the parts with iodole and ether, the pa- tient being instructed to breathe through the nostrils quickly if the application produces too much smart- ing pain. Three grains to the ounce of this mixture is a good strength for these tonic treatments, and the same combination, preceded if necessary by a two-per-cent, cocain spray to allay smarting, is very efficacious in reducing acute or subacute nasal and postnasal inflammation. In fact, it is good in temporary turgescence from any and all causes. Without doubt some cases of migrain are of the nature of 11 nerve storms " and are closely allied to epilepsy, but it appears very probable that these nerve storms are primarily brought about by some irritation of a nerve filament, such as is produced by contact of the inner surface of the middle turbinate body with the septum. My paper on "Hemicrania," written in 1893, contained the proposition that there are a certain number of headaches which can be cured, or at least relieved, by the proper treatment of pressures or 7 ■contacts within the nose. Added experience during the past four years, together with the observations of other workers, has amplified this idea until it surely appears that we are safe in advising those who come to us with a history of persistent or recurring neural- gia, clavus, sick headache, pressure on top of the head, or the deep frontal pain commonly termed catarrhal headache, to have their nasal and post- nasal passages put in the best possible condition. I am about ready to believe that from 70 to 80 per cent, of all cases of headaches of hemicranial order are due to removable causes located within the nasal passages or adjacent air spaces. As intimated above, the treatment par excellence for these obstinate cases in which we find evidence of nasal disease of whatever nature is the correction of that disease by the means indicated. If we have reason to think that the trouble comes from the ac- cessory sinuses these must be drained. If the space between the septum and a middle turbinated body is too narrow, or if this same body is overgrown anteri- orly or presses against the outer wall of the nose, pre- venting free access of air into or drainage of the sinuses, it must be reduced in some manner. If bony shelves, membranous or cartilaginous thickenings causing pressure are found, these should be taken care of. In some cases one fails to find any of these deformities, and perhaps at the time of examination there are no points of contact, but it will be noticed that the membranes are of a peculiar bluish-red color, and have a sensitive or relaxed appearance which is an indi- cation that within the next half hour there may be some localized spot of pressure. This condition 8 does not require operative interference, but will usually respond to persistent and stimulating treat- ment, together with proper regulation of the habits, manner of living, exercise, etc., and, according to Roe, if the patient resides in the Lake region, avoid- ing too great a quantity of night air in the sleeping apartment. One word further, regarding those patients suffer- ing from an attack of headache, who ask for tem- porary relief. Inspection of their nasal passages will perhaps show marked pressures in the olfactory region, which may be due to an acute or subacute inflammation without much chronic disease, and without osseous deformity or overgrowth. About ninety per cent, of these patients can be relieved in one or a few treatments by cleansing the nostrils, and using the iodole and ether mixture, preceded by a light two per cent, cocain spray, as described above. Sometimes this will have to be repeated in four or five hours, but one treatment usually breaks up ah attack. Cases number 22 and 27 in the ap- pended table well represent this class. The desire to be brief has hindered me from quot- ing other authors, who have written on headaches, and forced me to leave out many things that I would have liked to mention; still I hope that proof enough has been brought forward to cause the rhinologist to take a more active interest in reflex headaches. 9 No. Name. Began treatment. Relieved. Intranasal conditions. Remarks. Mrs. K. 32 April 16, 1892 Per cent. 40 Deep bony Severe sick 2. Miss J. 32 Aug. 18, 1892 40 shelf pressing into r. mid. turb. Enlarged headache each week. Bimon t h 1 y 3- Mrs. F. 45 Nov. 5, 1892 75 mid. turb. Enlarged sick headache. Bimon t h 1 y 4- Mrs. L. 35 Dec. 3, 1892 40 mid. turb. Septal shelf hemicrania. Severe hemi- 5- Miss H. 25 Oct. 7, 1892 TOO pressing i n f. turb. Septal shelf crania at times each week. Frequent 6. Mr. K. 56 April 14, 1892 IOO pressing i n f. turb. Enlarged hemicrania. Severe 7- Mrs. Y. 55 Feb. 23, 1802 IOO mid. turb. with thickened membranes. Septal shelf hemicrania tri- monthly. Clavus and 8. Dr. S. 30 Mar. 23, 1892 90 and deflected septum. Deflected sep- general head- aches. Hemicrania 9- Miss G. 32 May 9, 1892 90 turn pressing r. mid. turb. Deflected sep- once a week. Severe hemi- IO. Miss F. 25 Nov. 17, 1892 75 turn, large shelf, and mid. turb. Deflected sep- crania. Died of general tu- berculosis i n 1895. Severe hemi- IT . Mrs. C. 35 Jan. 17, 1893 75 turn, large shelf, etc. E n larged crania, when she has colds. Severe 12. Mrs. R. 50 Oct. 26, 1893 9° mid. turb. Atrophic weekly hemi- crania, pres- sure on top of head. Pers i s t e n t rhinitis, e n - larged turb. general head- aches almost constant. 10 No. Name. Age. Began treatment. Relieved. Intranasal conditions. Remarks. Per cent. 13- Miss C. 17 June 24, 1893 90 Enlarged mid. turb. Headach es and pressure top of head bi- monthly. 14- Mr. C. 38 May 18, 1893 100 Septal shelf and thickened mid. turb. General headaches. i5- Miss B. '9 Mar. 23, 1893 100 Septal shelf and swollen mid. turb. Severe sick headache b i- monthly. 16. Mr. M. 36 April 20, 1893 100 Septal shelf and swollen mid. turb. Severe sick headaches bi- monthly. 17- Mr. S. 38 May 21, 1894 40 Long shelf pressing into mid. turb., etc. Severe hemi- crania once a week. 18. Miss R. 26 June 27, 1894 75 Deflecte d septum, mid. turb., filling in- fundibula, r. s. Hemicrania bimonthly. 19. Prof. K. 36 Jan. 17, 1894 75 Thick mem- brane and en- larged turb. Severe and frequent hemi- crania. 20. Dr. L. 27 Dec. 29, 1894 90 Cartilagenous thickening, pressing mid. turb., 1. s. Deflected sep- tum pressing 1. mid. turb. S e v e re frontal head- aches, tri- monthly. 21 . Miss S. 65 April 18, 1894 9° General headaches. 22. Mrs. B. 33 May 11, 1894 9° Thic k e n e d membrane on mid. turb. and septum. F requent headaches. 23- Miss W. 33 Nov. 2, 1894 90 Mid. turb. pressure 0 n septum. Neuralgia and severe headache. 11 No. Name. •a3v Began treatment. Relieved. Intranasal conditions. Remarks. 24. Mrs. H. 32 Jan. 7, 1894 Per cent. 100 Mid. turb. Very fre- 25. Mr. C. 35 June 4, 1895 9° pressure on septum, filling infundibula. Thickenings quent, severe sick head- aches. Severe neu- 26. Mr. N. 28 Feb. 6, 1896 40 and enlarged mid. turb. Septal shelf, ralgia, and hemicrania. Cata r r h a 1 27. Mrs. L. 40 Oct. 1896 40 and thickened membranes. Swollen and headaches. Severe hemi- 28. Dr. B. 40 Oct. IO, i8q6 IOO sensitive mem- branes over mid. turb. Septal shelf, crania, when she has cold. F requent 29. Mrs. T. 37 Nov. 5, 1896 90 and sensitive membranes. Enlarged general head- aches. Very severe, 3°- Mr. S. 45 Oct. 2, 1896 40 mid. turb. Enlarge d sick h e a d - aches twice a week. Hemicrania mid. turb., and polypoid mem- branes. twice a week. The Medical Nezes. Established in 1843. A WEEKLY MEDICAL NEWSPAPER. Subscription, ^4.00 per Annum. The A merican Journal OF THE Medical Sciences. Established in 1820. A MONTHLY MEDICAL MAGAZINE. Subscription, $4.00 per Annum. COMM UTA TION RA TE, $7.30 PER ANNUM. LEA BROS & CO., NEW YORK AND PHILADELPHIA.