ACUTE MANIA FOLLOWING THE ENUCLEA- TION OF AN EYE. By W. CHEATHAM, M. D., Louisville, Ky. 1 1 F. B., age thirty-five, carpenter, was struck in the left eye, on September 30th last, by a spike six inches long, rupturing the eye at the inner sclero-corneal junction, and also at the insertion of the external rectus. I saw him late in the afternoon of October 1st. The whole organ was greatly inflamed, the chemotic con- junctiva, even at this early stage, overlapping the cornea. I advised immediate enucleation, which was done early on the morn- ing of October 2d, quite a good deal of hemorrhage following. The instruments were washed in boiled carbolized water, the sponges put in boiled water and hyd. bi-chlo., and the eye dressed with iodoform. The spike he was struck with was very dirty and rusty, and the patient fell on his face in the dirt when he was struck ; he was brought home with a dirty cotton hand- kerchief of a fellow-workman over his eye. October 3d there was great swelling of the parts, with great pain, and the patient was controlled with much difficulty ; he imagined he was from home, and some one wished to force him to join the church. Morph, sulph. was given him hypodermically and by mouth. October 5th he was very violent ; the parts were very tense. Pot. brom., in large doses, was added to the morphine. He would allow no local applications to be made. Drs. Mason and Cartledge were asked to see the patient with me. Thinking the morphine had some- thing to do with his present condition, bromidia was given in teaspoonful doses, every one, two, or three hours, until October 8th. This failing to quiet him, the morphine had to be used again occasionally. Sometimes it required four or five men to hold him in his bed. He recognized no one ; endeavored to do violence to his wife. October 13th I gave him hydrobromate of hyoscine, gr. four times a day. Just at this time the inflamma- tion began to subside and his mind to clear up. During his ill- ness his pulse and temperature were both normal, except the afternoons of October 10th and nth, when the former was 96 and the latter 99$°. The patient was discharged October 20th well. Reprinted from the Archives of Ophthalmology, Vol. xix., No. 1, 1890.