PROJECT REPORT COMMITTEE OR FOOD RESEARCH QUARTERMASTER FOOD AND CONTAINER INSTITUTE FOR THE ARMED FORCES CHICAGO ILLIKOI 8 IUIAICI AND DKVELOFMHT BRANCH MILITARY PLANNING DIVISION OFFICE OF THE QUARTERNASTCR GENERAL cobp ERXt(jN6 INSTITUTION University of Wisconsin LOCAL I TV Madison, Wisconsin 01VI 51 ON 11 1 1 11 ! College of Agriculture DEPARTMENT . Department of Biochemistry OfPVCI AL INVESTI SATQR Go A, Elvehjem collaiorators Eugene Mo Spor# REPORT NO. 5 PILE NO.' N-911 contract1 no. 7llCT009yqm-r . 9 YoR PERipb COVERING 1 September 1947 - 31 October 1947 initiation date 1 January 1947 TITLE* [X J PROGRESS REPORT [ j PHASE REPORT [ J ANNUAL REPONT [ ]t£RNINATION REPORT 0 Nutritive Value of Army Rations. SUMMARY Studies have been conducted on monkeys fed X rations to dphermir. \w effect when individual supplements of ©ight of the ten orywta ' in--- f • ' arc: ■ are administerede It has been noted that each of the folio vi kg * produced a weight response when fed .to monkeys-losing weight on tne thiamine, riboflavin, pyridoxin©, choline, folic acid ? nd not.*; folic acid were inactive in eliciting this, growth response u.:1 ; • was present as a supplement tc the diet-., Oral / folic acid ni p.yv, * an effect on the, hemoglobin concentration, in audition to growt; From these results, it appears that K ration toes not contain iv.t- . pyridoxin© and folio acid for the grow’ng monkey-. In one cas-v ••ho r- t of all supplementary vitamins from a monkey- on K ration caused dot. h tvo weeks„ Monkeys have been continued on the ; . ration pi in v various supplements are being fbd to note their effect upon tre , the animalSe Preliminary results indicate a growth response vr lei ■ o casein,' This is being checked with other animalsRecently started on preparations of the monkey antiamenia factor to <*.$'. ARMY effect® It is possible that a deficiency of this factor nhy c»ty low hemoglobin content of the blood noted even when vitamins a duce normal, growth in monkeys fed rations SCP 2 3 1950'. The S ration cannot support growth of monkeys when fecKj n U..|s3( < AtR Y mented forma The addition of s mixture of the. water-soluble proved the ration so that normal growth was obtained for a short penoa In one case, the addition of 10$ casein was sufficient to cont ■ ! .■ mal growth rate« This work is.being repeated with other animals Work has been continued on the effect of supplements 1:■ on oi: K ■" oion fed to rats. With K ration containing a double evel of 3 vlto -i uj •. basal, individual amino acids were fed at 0o?% of the iieta The aa.u continued 12-121 of phenylalanine had no effect upon growths lysine had an inhibitory effect*, the rats averaged 5 gms0 a week less than the basal3 methio- nine caused an increased growth of 4 gpis0 a week per rat above the basal group0 When all three amino acids were added to the diet* again no effect upon growth was observed0 The effects of lysine and methionine seem to counteract each other when fed simultaneouslyo With the information gained from work with K ration, the C and 10=in-l rations were fed in a similar mannerc The following results were obtained % s AvOo gain/week at end of 4th week (gnu ) (1) C ration alone 21 (2) ” ” plus vitamins A and D 21 (3) ” ’* ” " n M plus B vitamins 24 "j ft ft n » t» tt »» ft M It plus casein 33 (5) 10“in~i ration alone 18 (6) " " plus vitamins A and D 18„5 ft ft ft ft ft tl ft plus B vitamins 22 (8) 10“= in-1 ration plus vitamins A and D plus B vitamins plus 5% casein 27 • Normal growth of rats w«* obtained when C ration was supplemented with vitamins and oasein0 With the same supplements, 10»in-l ration was improved so that rats grew at a ±air but still at a suboptimum rate„ Vitamins A and D had no effect upon the growth rate0 Experiments have been started with rats to note the effect of the coffee in the K ration. The animals are being fed the ration with and without coffee,, and the results will be reported shortly <, In addition, studies have been undertaken with young dogse They are being fed the E and 10-in-l ration to note their effect upon hemoglobin and general appearance0 It is felt that a comparison of monkey, rat and dog results will give us a clearer understanding of the nutritional adequacy of the rations0 N-911 #5