October 14, 1959 Dear Marianne, What a fine review! I enjoyed reading it and I think the organization and completeness are admirable. A few minor corrections are included on another sheet; most of them could be disregarded if you choose, except for those concerning English grammar. By the way, the English is quite excellent throughout. How I wish I could do a tenth as well in French! I've been back at work since the beginning of September and I am fortunate to have a very fine woman to care for Amy. What a marvelous little girl she is -- a good spirit, fine sense of humor and enthusiasm for everything about her. Dan and I find her quite irresistible. At the lab I'm busy with many things. I'm back at our old manuscript and this time hope to get it completed. Also, Giulio and I are talking about publishing a note on the S-RNA-polynucleotide phosphorylase data now that we are thoroughly convinced that the residual RNA (dubbed S-RNA-p) has the same s.a. for picking up active amino acid as does the starting material. Also we have information on the base analysis and end groups so there is a fair amount of material. Since you'll be an author on this we'll send you the manuscript before sending it off. I think I have identified a 5'-phosphomonoester end on Giulio's preps -- which, as far as I can tell, is something new. Even more intriguing is that it appears to be all guanine -- that is the only 3' .5' diphosphate I've found pGp although I've looked for the others. This is still new so time and more experiments are needed. Best regards to Armand and your little girl and congratulations on a fine manuscript. Yours, Maxine Singer