COLE CAT. W'G' £ HEMlC-AZ. WaRF A RE 447 Information for Medical Officers Gas Warfare PREPARED IN THE OFFICE OF THE SURGEON GEN- ERAL, WAR DEPARTMENT WASHINGTON : : : 1917 »ri°atl Washington :: Government Printing Office :: 1917 NATIONAL LIBRARY OF MEDICINE Bethesda, Maryland Information for Medical Officers NOTES ON GAS WARFARE rT1HE subject of attack by gas is developing in all J- the services toward the greater importance of gas projectiles. Attack with projectiles allows of much greater opportunity for surprise than does the use of cloud gas, and it is al>o becoming more important to be on guard against projectile attacks of great inten- sity, producing very high concentration of poisonous gas in relatively short divisions of the front. Offen- sive gas officers are working toward the delivery of highly concentrated gases directly upon localities where relatively large numbers of men are congre- gated. " Direct hits " of this character must be looked for. GERMAN EXPERIENCE. Data is at hand relating to the experience of the Germans up to the end of August, 1917. The follow- ing from this source should prove of value to every medical officer. PROPHYLAXIS. Practice with the mask in order to be in readiness to meet the attack is of great importance. TREATMENT AT THE AID OR DRESSING STATION. Rest to the prevention of every bodily exertion is insisted upon. The clothing is removed in order to allow its thorough ventilation, presuming that it con- tains gas. Morphine is distinctly forbidden. Digitalis is given intravenously. If the heart's action is weak, caffein is given subcutaneously. Venesection is done on severe cases up to 200 to 600 c. c. of blood, 126450—17 [1] Gas W a r f ar e according to the degree of pulmonary edema. The greater the edema the less blood is drawn, because where much edema already has appeared the blood has become concentrated. The pulse also is watched as a guide to the stopping of venesection. Surgical venesection is done with free exposure of the vein. When there is great concentration of the blood and it refuses to flow, the radial artery is opened and later ligated. OXYGEN INHALATION. Oxygen is given according to the severity of the case for two periods of 10 minutes every hour up to four periods of 10 minutes every hour. At least 6 liters a minute is given. The breathing bag is never allowed to become empty. IN THE HOSPITAL. Cardiac stimulants are given, digitalis or strophan- thus. If time is important, caffein and camphor are added. Oxygen is given according to the requirements, and venesection if it has not been done. After this, calcium chloride in solution is given subcutaneously in at least four different parts of the body. The solution consists of 1 per cent calcium chloride in 0.5 per cent sodium-chloride solution. Novocain is used to relieve pain, and up to 800 c. c. of the calcium-chloride solution is given. This drug is believed to be indicated in severe cases and strict asepsis is necessary to prevent necrosis. Experiments on animals with calcium chloride ap- parently have proved its value. Of 24 treated ani- mals, 55 per cent died; of 24 untreated animals, 88 per cent died. Adrenalin is encouraged if the blood pres- sure is low. Atropin and artificial respiration are for- bidden. Small doses of veronal and codeine are given to relieve the cough, and menthol and alcohol are given Gas W ar f ar e by inhalation to relieve pain. Fluid must be freely given, possibly by enemata. IMPORTANCE OF DISCIPLINE. It is of importance to know that in the British Serv- ice the mask is always carried in the " alert position " when in the danger zone, which may be a considerable distance behind the front line. This is required be- cause of the danger from gas shells. It is easily pos- sible for a column of marching men to walk into an air pocket of gas, and if the men are unprotected, casualties will occur. British officers state that false unconcern, a spirit of fear of possible ridicule, has kept men from putting on masks and so has caused casualties. When there is danger of gas, masks must he required. NOTE ON EXPERIMENTAL DATA. The following extract is taken from a research report made by Yandell Henderson, engaged in investigations under our Gas Defense Service: There are at least four ways in which venesection probably may influence the condition of the gassed animal— 1. The asphyxial condition present would be improved by the increased hemoglobin accompanying bleeding. 2. The acidosis incident to gassing probably also would be counteracted by bleeding because of the increased alkali re- serve of the blood. 3. Bleeding would remove from the organism in large meas- ure any possible toxic substances formed as a result of the gassing. 4. Bleeding would alleviate the condition of the pulmonary edema. Experiments are being conducted with a view to im- provements in the treatment of gassed cases. [3] ^