'«^Vr*;*r-*.L/r- —* f>.VC*2 -rx'/Z-f av' ~- ~^%'X*^/r3 .-^ y,yjBCg • •"T^'"ft^j^f"iijL'^* **y~""' - ■Mlli'^TJJ.V.-- «W "If i1 iT.**.-.-* . - NATIONAL LIBRARY OF MEDICINE Washington Founded 1836 U. S. Department of Health, Education, and Welfare Public Health Service Jp THE SCIENCE AND ART SURGERY. A TREATISE ON SURGICAL INJURIES, DISEASES, AND OPERATIONS, BY • JOHN EEICHSEN, PROFESSOR OF SUEOERT AND OF CLINICAL SURGERY IN UNIVERSITY COLLEGE, AND SURGEON TO UNIVERSITY COLLEGE HOSPITAL. AN IMPROVED AMERICAN EDITION, FROM THE SECOND ENLAEGEDAND CAEEFUIIY EEVISED LONDON EDITION. ILLUSTRATED BY FOUR HUNDRED AND SEVENTEEN ENGRAVINGS ON WOOD. PHILADELPHIA: BLANCHARD AND LEA. 1859. 1653 Entered, according to Act of Congress, in the year 1858, by BLANCHARD AND LEA, in the Clerk's Office of the District Court of the United States for the Eastern District of Pennsylvania. COLLI N ST_ P & I X T £ K . AMERICAN PUBLISHERS' ADVERTISEMENT. The high reputation which this work has so rapidly obtained in this country, has stimulated the publishers to render the present edition in every respect worthy the confidence of the American profession. During its passage through the press the sheets have been submitted to a competent surgeon, with the object of embody- ing in it whatever might be requisite to its improvement. There has been found, however, but little to add; the careful revision and extensive additions of the author having rendered unnecessary most of the notes which were introduced in the former American edition, and having brought the work thoroughly up to the present condition of European surgery. A few notes and a small number of wood- cuts only have therefore been introduced, elucidating some points of American practice. These additions are enclosed in brackets [ ]. Philadelphia, December, 1858. (v) PREFACE. In preparing a Second Edition of this work for the press every page has been carefully revised. Some chapters have been almost completely re-written, the text has been considerably enlarged, and upwards of one hundred and sixty new illustrations have been intro- duced. The additions are almost exclusively of a practical charac- ter ; my wish being to make the work a guide to the practitioner as well as a text-book to the student. Having this double object in view, I have entered with much minuteness into many practical details, which I think will be found to be as useful to the student as they are important to the practitioner. My increasing experience as a teacher leading me to fear that there is no little risk of the cul- tivation of the Art not keeping pace with the progress of the Science of Surgery. The general arrangement of the work has been preserved. It is divided into three parts:—The First Division, under the head of "First Principles," contains some general observations on Operative Surgery, and more specially on Amputations, together with a con- densed view of the Nature and Treatment of Inflammation. The Second Division comprises the consideration of Surgical Injuries, and the Third that of Surgical Diseases. In considering both Injuries and Diseases it has appeared to me to be more consistent with a natural arrangement to treat 1st, of those common to all parts of the body, as Wounds, Abscesses, Ul- cers, &c. 2d. The Diseases and Injuries of Special Tissues, as of the Osseous Tissue,—Fractures and Necrosis; of the Vascular Tis- sue,—"Wounds of Blood Vessels and Aneurisms. And 3d. The Diseases and Injuries of Regions. The more Special Operations I have considered as part of the Treatment of the different Injuries and Diseases for which they are required; a plan that, I thought, would be more practically useful than to describe them apart as a separate subject. I have limited (vii) PREFACE. the Consideration of Affections of the Eyes to Injuries of those organs, their Diseases being a special subject, that would require for its proper description more space than could be allotted it in this Work. In discussing the numerous topics that are embraced in a system- atic Treatise on Surgery such as this, I have endeavored, so far as lies within its scope, and without entering into anything like an his- torical account, to ascribe to whomsoever it may be due the merit of improvements in Practice, or of discoveries in Pathology. In some cases, I may perhaps have accidentally omitted doing so, and in other instances, where the observation had become as it were the established and common property of the profession, I may pur- posely have avoided encumbering the text with names and refer- ences. In order to remedy this deficiency to some extent, I would beg to refer the reader to the more special Treatises on the subject- matter of the different chapters. Thus I would particularly direct his attention to the admirable Lectures on Pathology by Mr. Paget, to which I have been much indebted in preparing the chapters on Inflammation and on Tumors. To the works by Sir B. Brodie on Diseases of the Joints and Urinary Organs, to the Treatise of Stanley on the Bones, of Lawrence on Plernia, of Fergusson on Practical Surgery, of Cooper on Fractures and Dislocations, of Travers on Injuries of the Intestines, of Guthrie on Wounds of Arteries, of Sir R. Carswell on the Elementary Forms of Disease, and to those of Acton and Langston Parker on Syphilis. To the most excellent works of my former teachers, Samuel Cooper and Robert Liston, whose names I cannot mention without a ready and deep-felt expres- sion of gratitude for much valuable instruction and personal kind- ness received from them in former years, I would especially refer the reader. For any clerical errors in the work, I must beg the reader's indulgence. It has been prepared and written in the midst of the harassing and onerous duties that devolve upon a Hospital Sur- geon, a Teacher of Surgery, and a Private Practitioner in the Me- tropolis, and which are but little favorable to literary pursuits. In conclusion, I must express my acknowledgments to Mr. Hulme for much valuable assistance in carrying this volume through the Press. JOHN ERICHSEN. Loxdon, September, 1857. CONTENTS. DIVISION FIRST. FIRST PRINCIPLES. CHAPTER I. PAGE Operations in General — Chloroform — Ether — Causes of Death after Operations — Incisions —Sutures —Dressings —After Treatment..... 36 CHAPTER II. Amputations and Disarticulations — Stumps — Structure and Dressing of—Dis- eased Stumps — Statistics of Amputations.......36-47 CHAPTER III. Special Amputations — Amputations of Fingers, Thumb, Wrist, Forearm, Arm, Shoulder, Toes, Great-toe, Little-toe, Foot — Chopart's, Hey's, Pirogoffe's, and Syme's Operations — Leg, Knee, Thigh, Hip......47-67 CHAPTER IV. Increased Vascular Action — Congestion — Determination — Inflammation — Its Nature and Treatment—The Effusive, Adhesive, Suppurative, Ulcerative, and Gangrenous Forms of Inflammation........67—105 DIVISION SECOND, SURGICAL INJURIES. CHAPTER V. Effects of Injury— Shock — Traumatic Delirium, Varieties and Treatment of . 106-108 CHAPTER VI. Injuries of Soft Parts — Contusion — Wounds — Incised — Modes of Union of In- cised Wounds — Treatment—Contused and Lacerated Wounds — Traumatic Gangrene — Amputation in..........109-121 X CONTENTS. CHAPTER VII. Gun-shot Wounds — Apertures of Entry and Exit, Symptoms and Treatment of Resection and Amputation in........• CHAPTER VIII. Punctured and Poisoned Wounds — Stings of Insects — Snake Bites — Hydropho- bia— Dissection Wounds..........131-139 CHAPTER IX. Injuries of Nerves — Wounds of Blood Vessels — Hemorrhage — Transfusion . 140-142 CHAPTER X. Wounds of Veins — Air in Veins.........142-148 CHAPTER XI. Injuries of Arteries — Hemorrhage — Arrest of Arterial Hemorrhage — Surgical Treatment of Hemorrhage — Styptics — Pressure — Torsion — Ligature — Col- lateral Circulation — Treatment of Wounded Arteries — Traumatic Aneurisms — Aneurismal Varix— Varicose Aneurism — Accidents of Ligature—Secondary Hemorrhage — Gangrene..........148-176 CHAPTER XII. Wounds of Special Arteries — of Carotid — Subclavian — Axillary — Brachial__ Radial — Ulnar — Palmar Arches — Femoral and its Branches — Tibial, and Plantar.............176-183 CHAPTER XIII. Injuries of Muscles and Tendons—Sprains nd Strains— Ruptures of Tendons and of Tendo Achillis......... 183-184 CHAPTER XIV. Injuries to Bones —Bending of Bone — Fractures — Causes, Varieties, and Signs of—Union of Fractures —Treatment of Simple Fractures — Starch and Plaster Bandage — Accidents in Treatment of Fracture— Spasm —Extravasation — QMema—Gangrene — Complications — Compound Fractures, Treatment of__ Amputation in —Resetting of Fractures — Ununited Fractures and False Joints.............184-208 CHAPTER XV. Special Fractures — of Nose — Malar and Maxillary Bones — Lower Jaw__Clavicle — Scapula — Humerus — Forearm — Elbow, Wrist, and Fingers__Pelvis__ Femur — its Neck and Shaft — Patella — Leg — Ankle — Foot__Ribs . . 208-236 CONTENTS. XI CHAPTER XVI. Injuries of Joints — Contusions —Wounds — Traumatic Arthritis — Dislocations — Reduction of Dislocations — Complication with Fracture — Spontaneous and Congenital Dislocations..........236-246 CHAPTER XVII. Special Dislocations — of Lower Jaw — Clavicle — Shoulder Joint — Elbow — Wrist — Fingers —Hip — Knee — Ankle, Foot, and Pelvis.....246-272 CHAPTER XVIII. Injuries of Head — Cerebral Disturbance — Concussion — Compression — Ence- phalitis— Treatment of these Injuries—Suppuration within Cranium—Inju- ries of Scalp — Cephaloematoma — Wounds of Scalp — Fracture of Skull— Contre-Coup — Fracture of Base — Discharge of Blood and Serum from the Ears — Depressed Fractures — Punctured Fractures — Extravasation of blood — Wounds of the Brain —Trephining........272-296 CHAPTER XIX. Injuries of the Spine — Division and Compression of Cord — Dislocations of the Spine — Injuries of the Face — Nose — Ears — Foreign Bodies in — Injuries of Orbit— Eye-ball— Tongue and Mouth —Injuries of the Throat— Cut Throat — Asphyxia — Drowning — Hanging — Artificial Respiration — Foreign Bodies in Air Passages — Scalds of Air Passages — Injuries of GSsophagus . . 296-318 CHAPTER XX. Injuries of the Chest — Wounds of Lung — Emphysema — Pneumonia — Empyema __Hernia of Lung — Wounds of Heart and Large Vessels .... 318-324 CHAPTER XXI. Injuries of Abdomen and Pelvis — Rupture of Viscera — Wind Contusions — Buffer Accidents—Wounds of Intestines — Traumatic Peritonitis — Injuries of Bladder, Urethra, and Rectum — Foreign Bodies in those Canals — Laceration of Perineum............325-335 CHAPTER XXII. Effects of Heat and Cold — Burns and Scalds — Frost Bite .... 335-340 xii CONTENTS. DIVISION THIRD SURGICAL DISEASES. CHAPTER XXIII. Abscess —Varieties —Diagnosis, and Treatment of—Sinus and Fistula . . 341-348 CHAPTER XXIV. Ulcers — Healthy — Weak — Indolent — Irritable — Inflamed — Sloughing — Va- ricose and Hemorrhagic..........349-351 CHAPTER XXV. Mortification — Varieties of—Causes and Treatment — Spontaneous and Senile Gangrene — Amputation in ......... 352-360 CHAPTER XXVI. Gangrenous Diseases — Bed Sores — Sloughing Phagedena — Hospital Gangrene— Cancrum Oris — Boils — Carbuncle........360-364 CHAPTER XXVII. Erysipelas — Causes, Varieties, and Symptoms — Cutaneous—Cellulo-Cutaneous, Phlegmonous and Cellular — of Newly-born Infants — Head and Face — Scrotum — Pudenda — Fingers — Whitlow — Internal Erysipelas — Erysipelatous Laryn- gitis— Arachnitis—Peritonitis.........365-381 CHAPTER XXVIII. Purulent Infection or Pyemia — Visceral Abscesses — Theories of__Treat- ment.............382-387 CHAPTER XXIX. Tumors—Innocent and Malignant — Encysted Tumors — of Scalp__Horns__ Cysts — Simple and Compound — Hsematoma — Cheloid — Sarcomata__Wens__ Polypi —Fatty and Fibro-cellular Tumors — Fibrous — Malignant Fibrous — Recurring Fibroid — and Fibro-Plastic Tumors — Enchondroma__Malignant Tumors — Cancer Scirrhus — Encephaloid — Melanosis — Colloid__Treatment of Cancer by Compression — by Caustics — by Operation — Epithelial Cancer__ Ecraseur — Operations for the Removal of Tumors ..... 388-418 CONTENTS. xiii CHAPTER XXX. Scrofula — of Tissues and Organs—Tubercle — Causes and Treatment of Scro- fula .............. 418-425 CHAPTER XXXI. Syphilis—Primary Syphilis — Chancres — Varieties and Treatment of—Mercu- rial and Non-Mercurial Treatments compared — Consecutive Symptoms — Chancrous Induration — Bubo — Venereal Warts — Constitutional or Secondary Symptoms — Causes and Treatment of—Syphilitic Diseases of the Skin, Hair, and Nails — Mucous Membranes — Lips — Tongue — Throat — Larynx — Nose — Periosteum and Bones — Nodes—Necrosis — Iritis — Sarcocele — Infantile Syphilis — Symptoms and Treatment of.......424-456 CHAPTER XXXII. Diseases of the Skin and its Appendages — Warts and Corns — Onychia — Ingrowing of the Nail — Cheloid and Fibro-vascular Tumor — Lupus Non-exe- dens, and Exedens — Cancer of the Skin — Varieties of ... . 456-463 CHAPTER XXXIII. Diseases of the Lymphatics and their Glands — Inflammation of—Adenitis — Enlargement of.........• 464-467 CHAPTER XXXIV. Diseases of Veins — Phlebitis — Adhesive — Suppurative — and Diffuse — Patho- logy and Treatment—Varix, operations for......467-473 CHAPTER XXXV. Diseases of Arteries — Arteritis, Adhesive and Diffuse — Spontaneous Gangrene — Structural Diseases — Plastic and Fatty Deposits — Atheroma — Calcification of Coats — Ulceration — Rupture—Contraction and Occlusion .... 473-481 CHAPTER XXXVI. Aneurism — Varieties of— Structure of Sac — Pressure-Effects — Symptoms — Suppuration and Sloughing of Sac — Spontaneous Cure—Diagnosis — Causes — Medical Treatment — Surgical Treatment — Hunterian and Distal Operations — Accidents after Ligature — Recurrent Pulsation — Suppuration and Slough- ing of Sac — Gangrene — Treatment by Compression — Comparison between Ligature and Compression — Manipulation — Galvano-Puncture . . . 482-514 xiv CONTENTS. CHAPTER XXXVII. Aneurisms of the Lower Extremities — Inguinal Aneurisms — Ligature of Exter- nal Iliac Artery — Ligature of Common Iliac — Ligature of Aorta and of Inter- nal Iliac — Femoral and Popliteal Aneurisms — Ligature of Femoral Artery — Accidents following it— Amputation in Popliteal Aneurism — Ligature of Tibial Arteries.............514-529 CHAPTER XXXVIII. Aneurisms of the Neck and upper extremity — of Innominata Artery—Distal Operation for — Aneurism of the Carotid — Diagnosis of—Ligature of Carotid Artery — Ligature of both Carotids — Distal Ligature of Carotid — Aneurism of Internal Carotid — Aneurism of Subclavian —Ligature of Innominata — Liga- ture of Subclavian, in different parts of its course — Aneurism of Axillary — Ligature of Subclavian — Accidents that follow — Ligature of Axillary Artery — Aneurisms of Arm, Forearm, and Hand — Ligature of Brachial, Radial, and Ulnar Arteries............529-563 CHAPTER XXXIX. Aneurism by Anastomosis—Treatment of—Nevus—Varieties of—Mode of Liga- turing — Hemorrhagic Diathesis.........564-570 CHAPTER XL. Diseases of Nervous System — Neuritis — Neuralgic — Tic — Division of Nerves in — Neuroma — Tetanus — Symptoms and Treatment.....571-578 CHAPTER XLI. Diseases of Bones — Periostitis — Osteitis — Suppuration of Bone — Abscess in Bone —Trephining —Caries, its Nature, Symptoms, and Treatment — Operations for Caries—Necrosis — Symptoms — Pathology — Formation of New Bone__ Treatment of—and Operation for...... 579-593 CHAPTER XLII. Structural Diseases of Bone —Hypertrophy —Rickets, Mollities, and Fra its lips may at onoe be brought together. This may also be done even when large, if the patient be of a very irritable constitution and sensitive to pain, the whole dressing being performed whilst he is still under the influence of chloroform. But in fenerah when the wound is extensive, as in cases of amputation, I prefer, and aimos invariably adopt, the plan recommended by Mr. Listen, of leaving the wound untH TJ V ?leCe v \Gt lmt in\^Td between its HPS for ^ oAhree hours^ until its surface has become glazed; the lint is then carefully removed any Zo\ZTLS:fJ f" a7ay'anVhe »*» of the incision brou^t'^ apposition, the sutures being drawn tight and tied. Lon- strins of r,lUpr of moderate width should now be applied*; these may either°be o?kl, iatt or the common adhesive kind, both having advantages that recommend them hi Ci&Ji^^^P0,ldi,,? drdVantaSe"that -ludTtlm in others ine isinglass plaster is clean, unirntating, and, being transparent allows a good view of subjacent parts, but it has the disadvantage oToLin/and stripping off when moistened by the discharges or dressing wS nft S ders it a very inefficient snnnnrt Tko „„ dressings, which often ren- . .. , ,y luewi,iuu support, lne common adhesive nWpr i cases. It the patient be very greatly depressed, the infliction of so severe an injury as a double amputation might probably extinguish life at once; and if possible to wait after the removal of the first limb, and before the second was amputated, it might be desirable to do so, until the shock of the first operation had passed off; but if the patient were not too much depressed, the double simultaneous amputation would probably be the safe course. On examining the structure of. a stump, after a year or two have elapsed from the time of its formation, it will be found to be composed of a mass of fibro-cellular tissue, the muscular and tendinous structures that enter into the formation having become thus trans- formed. The ends of the bones will be found to be rounded, and the medullary canal filled up, the vessels being obliterated up to the nearest collateral branch (Fig. 2). The ends of the nerves are thickened, and commonly assume a bulbous appearance (Fig. 3). On examining these rounded or oval tumors, they will be found to be fibro-cellular masses having nervous fibrillae thinly scattered throughout. The proper adaptation of artificial limbs is a matter of considerable consequence, and the ingenious mechanical contrivances that are at the present day adapted to stumps, leave little to be desired. The surgeon had better leave the details of these mechanical contrivances to the instru- ment-maker; but he should see that they are made light, consistently with sufficient strength and support, and that the end of the stump is never pressed upon by them.1 Thus, after amputation of the thigh, the artificial limb should take its bearing point from the lower part of the pelvis and hip. In amputa- tion immediately below the knee, this joint should be bent and received into the socket of the instrument, and if the amputation be at a lower point than this, and the stump be extended into the artificial limb, its end must be pro- tected from injurious pressure. Even in the case of disarticulation at the ankle- joint, where the soft tissues of the heel are left, pressure can seldom be borne upon the end of the stump. Morbid conditions of stumps. — It not unfrequently happens that the end of the bone in a stump necroses. This occurs either in consequence of the injury inflicted by the jarring of the saw, or happens in those stumps that unite by the second intention, and where the bone consequently lies bathed in pus for a considerable time, being exposed between the flaps, and thus at last losing its 1 [The most perfect of all the artificial limbs we now possess, is the one invented by Mr. Palmer, Chestnut Street, Philadelphia. This piece of mechanism received the prize- medal at the London Exhibition of 1851. It merits the entire confidence of the surgeon."] DRESSING AND STRUCTURE OF STUMPS. 41 vitality. This is especially apt to happen in persons of feeble constitution in whom the limb has, previously to the operation, been the seat of abscess that denudes or otherwise injures the vitality of the bone. In these cases a fistulous opening will be left leading down to the necrosed bone, which usually separates three or four months after the Fig. 4. operation in the shape of a complete ring, with irregularly- spiked prolongations stretching from its upper part (Fig. 4); after this has been removed, the stump becomes firmly consolidated. Conical or sugar-loaf stumps, as they are called, com- monly form in consequence of the flaps having originally been cut too short, but in other cases they may occur, though the stump may have been skilfully fashioned, in consequence of the soft parts which have been the seat of inflammatory action and suppuration before the amputation, retracting during the granulating process, so as to denude the bone. In such cases as these, great retraction and contraction of the flaps are apt to go on during cicatriza- tion, so that the bone may never be covered at all, but be exposed at the bottom of an irritable ulcer; or if the soft parts do coalesce, the cicatrix will be unable to support the slightest pressure without becoming ulcerated. Under these circumstances, the only remedy consists in laying open the stump, and cutting off about three inches of the bone. If the stump be too long and projecting, so as constantly to be in the patient's way, there is no remedy but to perform a second amputation higher up. This is espe- cially required in badly fashioned stumps of the leg where the limb has been removed too far below the knee, so that it projects backwards in an awkward manner, and is constantly liable to accident when the patient uses a wooden pin. Painful and spasmodic stumps. — The nerves in a stump naturally become somewhat expanded and bulbous; and no material inconvenience results from this condition. But it occasionally happens that a distinct tuberose enlargement forms in connection with one of them, attaining the size of a cherry or a walnut, and this being pressed against the end of the bone, or implicated in the cicatrix, becomes the seat of intense pain of a neuralgic character, more particularly whenever it is touched. Under these circumstances excision of this bulbous extremity of the nerve is necessary, and will effect a cure. But besides this form of painful stump, which may happen in the strongest and healthiest subjects, and is entirely dependent on losal causes, there is another condition in which the stump becomes not only the seat of intense pain, but usually of convulsive twitchings. This form of painful stump arises from con- stitutional causes, and invariably occurs in females, more particularly in those of the hysterical temperament, and who are subject to neuralgic pains elsewhere. In these cases the general cutaneous sensibility of the stump is increased; it is often the seat of convulsive jerkings or twitchings, and the pain is of a more or less intermittent character, being increased under the influence of various emotional and constitutional causes. In cases such as these, the treatment should be conducted on the general principles that will be fully discussed when we come to speak of neuralgia. No excision of the nerves of the stump, or even amputation higher up is of any avail: the disease being constitutional, will certainly return in each successive stump, until at last the shoulder or hip may be reached without any permanent benefit accruing to the patient. Aneurismal enlargement of the arteries of a stump is of extremely rare occur- 42 AMPUTATIONS. rence. The only case with which I am acquainted, is one ™orde Care ™st be taken tit the edge of the bistoury be not mchned too much backwards, lest it slip over the astragalus and open the ankle-joint; or too far forwards, lit it pass anterior to 1. Line of amputation of great toe. 2. Line of Chopart's ope- ration. 3. Lines for excision of os calcis. amputations of the foot. 57 the scaphoid—between it and the cuneiform bones. After disarticulation has been produced, the projecting head of the astragalus should be sawn or clipped off. The result of this operation is extremely favorable, the patient, by the aid of a properly constructed boot, being able to walk, and even dance with very little appearance of lameness. In some cases where the muscles of the calf are very strong, and calcaneum projecting, the heel becomes drawn up, and the centre edge of the stump made to point down in such a way that the patient is rendered lame by walking on the anterior sharp edge of the calcaneum, which irritates the flap. This condition is best removed by division of the tendo Achillis. Disarticulation of the foot at the ankle-joint was first reduced by Mr. Syme to a regular operation. By its performance amputation of the leg may often be avoided, the patient being left with an exceedingly useful stump, which, as its covering is ingeniously taken from the heel, constitutes an excellent basis of support (Fig. 34). The operation is performed by making an incision from the anterior part of one malleolus downwards and backwards, across the plantar surface of the heel, to a corresponding point in the opposite malleolus (Fig. 31). This flap is well dis- sected back, the knife being kept close against the bone, especially when it passes towards the inner side of the os calcis, in the neighborhood of the plantar arteries (Fig. 32). An incision is next made across the dorsum of the foot, from the upper Fig. 31. extremity of the sole flap on one side, to that on the other, and the joint opened from the front. The lateral ligaments should now be touched with the point of the bistoury, and the tendo Achillis divided by pressing the foot forcibly downwards and cutting from before back- wards (Fig. 33) by some twisting and dissec- tion ; at the same time the os calcis is com- pletely separated from its soft attachments, and the foot removed; the two malleoli must then be sawn off, the plantar arteries tied, and the flap brought up. A well-formed rounded stump will thus be left as represented in Fig. 34. Fig. 32. Fig. 33. Fig. 34. In performing this operation, care must be taken that no button-hole aper- tures are made through the posterior part of the heel flap. This may commonly 58 SPECIAL amputations. be avoided readily enough whon the soft structures in this situation are greatly thickened and infiltrated by plastic matter, as the result of chronic disease; but if the operation be required for injury of the foot, great care is required in digging out the heel, the integuments at the posterior part of the os calcis being very thin and adherent to the bone. It is also of importance that the incision across the heel should be carried well back over its point (Fig. 32). Unless this be done a large cup-shaped flap will be left, in which blood and pus will accumulate, and the cicatrization of the stump will be much retarded. The principal point, however, to be attended to is, that the plantar arteries are cut long; unless care be taken to do this, the flap will be insufficiently supplied with blood, and sloughing, especially of its outer angle, to which there is in all cases a tendency, will be particularly liable to occur. As union takes place by granulation, there will be a tendency to bagging in the stump, but this may be prevented by proper bandaging. The tendency to sloughing and to undue sup- puration chiefly occurs in those cases in which the amputation has been per- formed as a primary operation for a crush of the foot. In one case, in which I had occasion to perform it for an injury of this kind, a good deal of trouble resulted from this cause, though eventually the case did perfectly well, and the patient now walks with scarcely any difficulty. Various modifications of Syme's amputation may at times be practised with advantage, in consequence of the soft part covering the heel being more or less ulcerated or disorganized, so as not to admit of forming a good basis of support. Under these circumstances, the flaps may be fashioned from the sides instead of from behind; and in this way I have more than once formed an excellent covering to the end of the stump. These lateral flaps should not, however, be made in any case that admits of disarticulation at the ankle in the ordinary way. In no case do they afford so great a basis of support as the integuments of the heel, which are far more dense and elastic. Pirogoff's modification of Syme's operation consists in the preservation of the posterior portions of the os calcis which is left in the heel flap. The opera- tion is performed in in the following way: — the incision is carried across the sole of the foot, from one mal- leolus to another; but the flap thus formed is only dissected here about two lines. Disarticu- lation of the astragalus is then effected in the usual way by an incision across the front of the foot. A narrow saw is now ap- plied to the upper and back part of the os calcis behind the astragalus (Fig. 35), and the bone cut obliquely downwards and forwards; the malleoli are then removed and a thin slice of the articular cartilage taken off. The advantages of this operation over the ordinary mode of disarticulation consist in the stump being larger and better adapted for pressure,—in the readiness of the union of the two applied osseous surfaces,—and in the less likelihood of the vascular supply in the posterior flap being interrupted, as its vascular communications are not much disturbed, and the posterior tibial artery can always be cut long The Subastragaloid amputation is another mode of disarticulating the foot In it the heel flap is made as in Syme's operation, and the articulation between Fig. 35. AMPUTATIONS OF THE LEG. 59 the astragalus and scaphoid being opened (the ankle-joint left intact), the bistoury is passed under the astragalus, between it and the calcaneum, which, together with the rest of the foot, is removed. In this amputation a good, long, useful stump results; but the cases requiring it must be few, as it does not often happen that the calcaneum, together with the anterior range qf tarsal bones are diseased, without the astragalus also being involved. In cases of caries of the tarsus requiring amputation, it occasionally happens that the surgeon cannot determine with certainty, whether the morbid action is limited to the anterior range of tarsal bones, or extends so far backwards as seriously to implicate the astragalus and calcaneum, and is consequently unable to decide whether the foot admits of removal by Chopart's operation, or requires disarticulation at the ankle-joint. Under these circumstances all doubt will be cleared, and the proper operation performed, by making an incision across the dorsum of the foot in the line of the astragalo-scaphoid and calcaneo-cuboid articulations; these are then opened, and the state of the bones examined. If the astragalus and calcanenm be sound, or but slightly diseased on their anterior aspect, Chopart's operation may be done, and any carious bone left behind gouged away. If, on the contrary, these bones be found to be deeply implicated, the flap may be dissected back for about an inch, and disarticulation at the ankle-joint proceeded with. It may also be well to bear in mind, that the tarsal articulations may have become so anchylosed, as the result of old disease, as to require the application of the saw. Amputation of the leg may be performed in three situations; either just below the knee, in the middle, or in the lower third of the limb. The selection of the line of amputation must depend upon the extent of the disease, but, wherever practicable, the amputation should be performed low down; the mor- tality diminishing in proportion as the limb is removed near to the ankle. Of 106 amputations in this situation done in Paris there were only 13 deaths. Surgeons used formerly, even where the disease or injury was limited to the foot, to amputate immediately below the knee; in all those cases in which the patient would be obliged to wear a common wooden pin, the long leg stump Fig. 36. being highly inconvenient when the patient rested on his bent knee; whereas to those individuals who could afford the expense of a well-constructed artificial limb, the amputation was done in the lower part of the leg. But this difficulty has of late years been removed by the introduction of a short wooden pin, in the socket of which the stump is fixed in the extended position; and amputation in all admissible cases should consequently, even amongst the poorer classes, be done at or below the calf. The flap amputation of the leg may be performed in the following way. The tourniquet having been applied to the artery in the popliteal space (Fig. 36), 60 special amputations. the assistant, whose duty it is to retract the flap, takes his stand in this, as in all amputations of the lower extremities, opposite to the surgeon. In the left limb, the point of the knife is entered at the posterior edge of the tibia, carried forwards for a distance of one inch and a half, then across the anterior part of the leg to the posterior border of the fibula, up which the incision is made to extend to a corresponding distance. In the right leg, the same incision com- mences on the fibular side of the limb, and terminates on the tibial. The flap thus formed, which should be broad and well rounded, is next dissected up by a few touches of the point of the knife, and transfixion of the limb made by passing the blade across behind the bones, from one angle of the incision to the other. The posterior flap is then formed by cutting obliquely downwards and backwards, and should be about three inches long. The bones are next cleared by a double sweep of the knife, and the interosseous soft parts divided by car- rying the instrument in a figure of 8 way between the bones. In doing this, especial care must be taken not to direct the edge upwards, so as to split either of the tibial arteries, more particularly the anterior: for as this vessel retracts Fig. 37. above the membrane, its ligature when divided too high, is no easy matter In sawing the bones, the fibula should always be cut firlt/as otherwise it will be pretty sure to be splintered. This bone may be best divided on the leftside by sinking the hand below its level of the limb, and using the heel of the saw and on the right, by holding the hand above'the limbfand^ cutting^ with the end of the instrument (Fig. 37). ' ^wng witn tne If the limb be very muscular, a large pad of the muscles of the calf will be left in the posterior flap; this will usually be a trood HpaI in +\1 ™ T • treatment; it may 8l„aghP/a„d thus interfere with pTpe/ l" t ZetS I have advantageously removed at one sweeD of th* lrnifi, +1. T ,.' the muscular mass thus left, thus leaving ifttlemore than *1*"?*' Pf * °f order to avoid this, the best operation consfsts' n sS casesV, W P V 1D skin-flaps on the anterior and posterior aspec softheS Jlten" T^ circular cut through the muscles. In this way thendTof the t S ' but a thin covering; but this matters little if th^operation tvlrZVT™ below the knee, for the patient bearing upon the Si" rft^ J exercises no pressure upon its cicatrix when an artificial limb is adnr!^ f 7' Amputation through the knee-joint, originally t*\Z£^§^ ''nd amputations of the knee and thigh. 61 practised by Velpeau and other Continental surgeons, has recently found favor in this country and America. The operation may readily be performed in the following way. An incision is made directly across the knee-joint above the centre of the patella. The skin-flap thus formed is dissected back, and the joint being opened above the patella, and the ligaments divided by a few touches of the knife, a long posterior flap is cut from the upper part of the calf of the leg, by passing the knife behind the tibia and carrying it downwards for a suitable distance. The exposed articular surface of the femur is then to be sawn off. The only large vessel requiring ligature will be the popliteal. Some surgeons prefer making a long anterior skin-flap and a transverse cut through the soft structures of the ham. The anterior flap falls over the end of the femur, and being composed of the tough and extensile integument of the knee, constitutes an excellent covering to the bone well adapted for pressure. This amputation may sometimes conveniently be varied by being done through the condyles without previously opening the knee-joint. The anterior flap is fashioned as before, the posterior flap is then made by transfixion behind the joint, and the bone being so cleared, the saw is applied immediately above the articulation, and the limb thus removed (Fig. 88). The .result is the same in Fig. 38. whichever way the operation is done fT\ The advantages of this operation over / / amputation of the thigh higher up are ^\. / / undoubtedly great. The limb being re- ^^\^ £/ moved at a greater distance from the /l^^B^bk trunk, the shock to the system will be /RSIR^Il^ less, and the rate of mortality diminished. /JF^1»J|mm| The medullary canal of the femur not /&% Sj**m being opened there will be less likelihood $fm^iipP !S§fl of osteomyelitis; fewer ligatures will be ^^^^Mi^aj^fjP^^^jjjr^ required, and if desirable these may be f/\5< ^^^f^ brought out through an opening made Mr | \ ^%k in the centre of the posterior flap, as Mr I \ ^m. Blandin recommends; and lastly, a longer m \ j ^m stump will be left, the movements of \j ^ which are more under the control of the patient than a shorter one, owing to the proper muscles of the femur not being divided, and thus all the movements of that bone being preserved in their integrity. There is a little point of practice that I have found useful in this amputation, viz., to round off with the saw the sharp edge left on the condyle after the removal of its cartilaginous surface, and which otherwise may press injuriously upon the flap. Dr. Markoe finds that out of 40 cases in which this operation has been done, there have been 17 deaths: a rate of mortality equal to 37 per cent. Amputations of the thigh are commonly required, both for accident and for disease; they may be performed in three situations: immediately above the knee, in the middle of the limb, or in its upper third. In the amputation in the lower and middle third, a tourniquet may be applied high on the limb: but when the operation is done in the upper third there is no space for the applica- tion of this instrument, and the surgeon must then trust to an assistant com- pressing the artery as it passes over the brim of the pelvis. This is best done by grasping the great trochanter with the fingers of the right hand, and then applying the thumb firmly over the artery; upon this the other thumb is then pressed as firmly as possible, and thus all chance of letting the vessel slip is prevented. Amputation above the knee, or Vermale's operation, is best done by lateral flaps. In performing this operation, the outer flap should always be made first. 62 SPECIAL AMPUTATIONS. The point of the knife being entered in the middle of the thigh, about three inches above the upper border of the patella, is carried close round the bone and brought out through the centre of the ham; the flap is then cut downwards and outwards; the knife being entered again in the upper angle of the incision, is carried close round the bone to its inner side, and the inner flap made by a sweeping cut (Fig. 39). Unless the blade be kept in contact with the bone in Fig. 39. Fig. 40. this situation the femoral artery is very apt to be split; the flaps being then re- tracted, the bone is cleared by two sweeps of the knife, and sawn about four inches above its articular surface. In the middle and upper third of the thigh, the antero-posterior flap opera- tion is to be preferred. In ordinary cases the anterior flap may first be made, and the posterior one subseqently fashioned by transfixion (Fig. 40). If, however, the patient be very much emaciated, it is dif- ficult to get a good cushion from the ante- rior part of the thigh in this way, and it is consequently preferable to follow the plan recommended by Mr. Luke, of making the posterior flap first by transfixion, and the anterior one afterwards by cutting from without inwards (Fig. 41). In some instances in which the tissues at the pos- terior part of the thigh are much diseased or injured, whilst those on the anterior aspect of the limb are sound, a very good stump may be fashioned by making a long square anterior flap by transfixion, and then cutting at one stroke of the knife through the soft part at the posterior aspect of the limb in a somewhat oblique direction from below upwards. The ante- rior flap when laid down will form the cushion at the end of the stump. If the patient be excessively muscular, and the amputation be a primary one, I think it is better to make skin-flaps with a circular I„ thi, wav the harge gaping fleshy ^£^£tZ£ff£ into unhealthy suppunmon and sloughing, and lead to the death oHhe patie™° AMPUTATIONS OF THE THIGH AND HIP. 63 Amputation through the trochanters may sometimes be advantageously prac- tised, either in severe compound fractures of the lower part of the thigh, or in cases of those malignant cartilaginous or osseous tumors of the lower and mid- Fig. 41. die third of the femur, and thus the more severe and dangerous operation of disarticulation at the hip avoided. Indeed, should it be found after section of the bone that this is so much injured or diseased as to require removal at the joint, this may readily enough be done by dissecting the head out of the ace- tabulum with a strong scalpel or bistoury. Amputation at the hip-joint has been performed in a variety of ways, which it is not necessary to detail. The simplest and speediest consists in making a large and thick anterior flap by transfixion, and a short posterior one from the gluteal region and back part of the thigh. In order to perform this operation properly, the patient's body must be brought well forward upon the edge of the table, so that the nates project beyond it, with the sound limb tied to the leg of the table. One assistant, whose duty it is to raise the anterior flap and com- press the arteries as they are cut, should stand behind the surgeon; another must have charge of the limb and impress such movements on it, as to bring the head of the femur into the best position for the proper performance of the operation. The duties of both these assistants are of the utmost importance, and should only be entrusted to fully competent persons. The pelvis and body Fig. 42. must be well steadied by two or three others. The knife, which must have a blade twelve inches long, requires to be entered and the flap to be made in dif- ferent ways, according to the side of the body on which the operation is per- 64 SPECIAL AMPUTATIONS. formed. If it be on the left side, the knife should be entered about two fingers breadth below the anterior superior spine of the ilium, and carried deeply in the limb behind the vessels, and directly across the joint; its point being made to issue just above the tuberosity of the ischium (Fig. 42). In transfixing, care must be taken not to carry the point of the knife too high, lest it enter the thy- roid foramen. The anterior flap must then be rapidly cut downwards and for- wards, about five inches in length. The limb which had, during this stage of the operation, been raised and slightly flexed upon the abdomen, must now be forcibly abducted and everted; the capsule of the joint is then to be opened by a firm cut with the point of the knife. So soon as this is done, the head of the femur must be pushed up, so that it may start out of the acetabulum; the heel of the knife is then passed behind it, the remainder of the capsule cut across, and the posterior flap rapidly fashioned by carrying the knife downwards and backwards through the thick muscles in this situation. When the amputation is performed on the right side, the anterior flap is made by entering the knife just above the tuberosity of the ischium, and bringing it out two fingers' breadth below the anterior superior spine of the ilium (Fig. 43); the remaining Fig. 43. steps of the operation being performed as in the last case. In those cases in which amputation at the hip is performed for a severe compound fracture of the thigh high up, it may be somewhat more difficult to get the head of the bone out of the acetabulum, as the surgeon is deprived of the long lever afforded by the limb by which the head is tilted upwards and forwards. In such cases as these, he must seize the broken fragment and draw this down at the same time that he pushes forwards its head and cuts firmly and fairly upon it In a case in which I amputated at the hip for compound fracture of the thigh two inches below the trochanters, I found it necessary to use much force in depress- ing the lower end of the fragment, and thus elevating and turning out its head m In amputation at the hip-joint, the great danger to be apprehended is exces- sive hemorrhage, the incisions being made so high up that no tourniquet can be applied, or pressure of the artery in the groin trusted to. It is therefore of great importance to perform the operation with as much rapidity as possible, and the disarticulation ought to be effected in, at most, thirty or forty seconds! The arrest of the hemorrhage during the operation must be entrusted to an assistant who can be fully relied on. His business should be to compress the artery above the brim of the pelvis, and then to follow the knife in the first in cision, and as the anterior flap is being made, slip his fingers under it and grasp AMPUTATIONS AT THE HIP. 65 it firmly above and below, so as to compress the femoral aftery in it, which is divided as the knife cuts its way out (Fig. 44). By grasping the flap tightly, Fig. 44. there will be but little risk of undue hemorrhage from the femoral artery; but lest it should slip, or the assistant whose duty it is to attend to it by any chance fail in holding it properly, it may be well to direct one of the assistants, whose business it is to steady the trunk, to have his thumb well pressed down into the iliac fossa, so as to compress the artery against the brim of the pelvis. As the posterior flap is being made, the bleeding from the gluteal and sciatic vessels, which is often very free, may be arrested by two assistants being in readiness to cover and compress them with the fingers or sponges. The arteries may then be ligatured one by one, as the assistant raises his fingers from them. If he have good hold of the femoral, the vessels in the posterior flap may be tied first; but if the femoral be insecurely held, it must first be tied. The femoral arteries, both superficial and deep, will be found to be cut long and to project from the muscles by which they are surrounded, so as very readily to be seized by the fingers or forceps, pulled out and ligatured. The arteries in the poste- rior flap and on the inner side of the joint will be found in the intermuscular septa. Another point of importance in this operation, in making the first punc- ture across the thigh, is to avoid wounding the opposite limb, the scrotum or the obturator foramen; this may be done by keeping these parts out of the way of the knife, and carefully guiding its course parallel to, but not against the pelvis. Amputation at the hip-joint has been performed, so far as I can ascertain, in 126 cases; of these 76 died. In 47 instances it was for injury; of these 35 proved fatal. In 42 cases in which it was done for chronic disease, 24 recovered and 18 died. According to Dr. S. Smith, the mortality from this operation has been much less of late years than was formerly the case, and this is doubtless true so far as amputation at the hip-joint for disease is concerned; but in cases of injury the procedure is still a highly unsatisfactory one. In all the 12 cases 66 CONGESTION. in which it was done in the Crimea it proved fatal. The diminution of late years in the mortality when this operation is practised for disease, is doubtless in a great measure due to the better selection of cases, but especially to the em- ployment of anaesthetics, by which the severe shock to the system that usually results from so severe a mutilation is necessarily materially lessened. CHAPTER IV. CONGESTION. Congestion plays an important part in surgery, it occasions serious structural changes, and runs into inflammation. Congestion is always a passive and me- chanical condition, hence the term active congestion should not be employed. Indeed, what has been described as "active congestion" is in reality a variety of the inflammatory process. Congestion is a true hyperaemia; in it we find not only that the blood is greatly increased in quantity, but that it circulates languidly through the part, and is of a darker color than natural. The arteries are at most of their normal size, perhaps even contracted; the veins and capillaries are greatly distended by the slowly-moving fluid. When the circulation in the congested part becomes completely arrested, stagnation is said to have occurred. The symptoms of congestion are well marked when the part affected can be seen or felt; when occurring in an internal organ they are often very obscure. Congestion of an external part, may be recognized by the changes it induces in the color, the feel, the size, the sensibility, the temperature and the functions of the part that it affects. The color of a congested part ranges from purplish red to a dusky brown; its size is increased; it feels soft, and pits under the pressure of the finger. The patient is often conscious of a heavy, dull, achin<* sensation in it, scarcely amounting to pain, but yet attended with uneasiness° The temperature is never above, but often below, the natural standard, and the functions are lessened in activity. . The existence of congestion in an internal organ may be ascertained by finding its size increased, its functions modified, with a sensation of weight in it The effects of congestion are of much surgical importance. The first change that usually takes place is an effort in the vessels of the part to relieve them- selves by a transudation of the more watery constituents of the blood into the surrounding cellular tissue. Hence distension of the cells of this tissue by the enused iiuid, giving rise to adema. J If the turgidity of the vessels be great, and their walls at the same time weakened rupture will occur and hemorrhage on to the surface, or into the sub- stance of the part, ensue. ; In consequence of the infiltration of the cells of the part, softening takes place nutrition becomes less and less perfectly performed, and ulceration at ast occurs. These changes we not unfrequently see in the integuments of the legs of old people. In other cases the vessels becoming permanent^dilated the part assumes habitually a redder or darker tint, becom^TwX^anS tftt be a mucous surface, it may be roughened and papillated, as is often observed in a congested conjunctiva. ^" uuntnou The causes of congestion, always mechanical, may be divided into two -reat classes, which we often find conjoined. 1st. Those causes that act by obstruct- DETERMINATION OF BLOOD. 67 ing the return of the venous blood; 2d. Those that act by enfeebling the walls of the capillaries and veins, so that they are no longer able to withstand the outward pressure of the contained blood. Amongst the first set of causes may be specified, any condition that directly and immediately interferes with the proper return of blood through a vein ; in this way the pressure of a tumor upon such a vessel produces congestion of the part from which it carries off the blood. Venous obstruction does not always act in so direct a manner as this, for it not unfrequently happens that obstruction to the return of blood from one organ, will occasion a congestive condition of the vessels in a distant one. Thus we find that some forms of congestion of the eye-ball are due to obstruction in the branches of the portal veins. The long-continued dependent position of a part may occasion its congestion by the blood mechanically gravitating into it, and overcoming, by the pressure thus brought to bear upon the vessels, the onward movement of the fluid within them. Thus we see congestion of the legs from long-continued standing; of the hemorrhoidal veins from an habitually sedentary life; and of the posterior part of the lungs of those who have been long confined to the recumbent position. Amongst the most common causes of congestion that act by enfeebling the vessels, we find the debility of old age, acting partly by lessening the tone of the vascular system generally; and partly by inducing a diminution of the pro- pulsive power of the heart. So also cold, by lessening the vitality and retarding the circulation of a part, produces congestion of it. Certain typhoid, or ady- namic states of the system, favor the occurrence of congestion in the more dependent parts. And lastly, inflammation may terminate in this condition. The obstructive causes are especially apt to induce congestion when they occur in connection with a feeble condition of the vascular system. The treatment of congestion has strict reference to its cause. The first indication consists in the removal of any source of obstruction to the return of blood from the part, as by unloosening a ligature, or elevating a part that has been too long dependent; or, less directly, as in the case of many internal congestions, by restoring the freedom of the circulation through the larger viscera. Thus, a congested eye or pile may be relieved by the removal of hepatic or portal obstructions. The next indication consists in lessening the quantity of blood in the con- gested part. The mere removal of the obstructing cause may effect this. In other cases, the direct removal of the blood by scarification, as in a congested conjunctiva, or by leeches, as around a turgid pile, affords immediate relief. In some parts again, the judicious application of a bandage will prevent or remove congestion. With this view the hand and arm are bandaged before the apparatus for a fractured clavicle is applied : and in varix the leg is supported by an elastic stocking, to lessen the pressure of blood in the dilated veins. The third indication in the treatment of congestion, consists in constringing the dilated vessels by the direct application of an astringent to them; thus we habitually apply nitrate of silver to a congested mucous membrane, and cold douches to many external forms of the disease. DETERMINATION. Increased vascular action lies at the bottom of most surgical processes; few important surgical actions taking place without it. No process by which the separation of dead parts is effected, or by which the repair of wounds or ulcers is carried out, can occur without an increased activity of the vessels of the parts concerned. Every tissue is susceptible of it; and the surgeon often excites it intentionally as one of the most efficient of his therapeutic means; hence an 68 INFLAMMATION. acquaintance with the elements and the details of the process, with its nature, symptoms, causes, results, and terminations, is of the first moment. Increased vascular action is of two distinct kinds: 1st. Determination ; 2d. Inflammation. These two conditions, though in practice most commonly found more or less conjoined, require to be studied separately. In determination, the blood is increased in quantity, of a bright arterial color, and circulates through the parts with great rapidity. This condition, which is often called " increased action," consequently resembles congestion in the blood being in excess, but differs from it in every other respect. Determination of blood is a vital process, often of a very transitory character, and frequently occurs as a normal action in those conditions of the system in which, for temporary purposes, an increased afflux of blood is called for by par- ticular organs. The enlargement of the mamma before lactation, and the turgor of the erectile tissues, afford familiar illustrations of this act. The surgeon often employs determination of blood for therapeutic purposes. Under these circum- stances, therefore, it cannot be considered a disease. When determination of blood is of a chronic or continued character it may lead to such changes in the appearance, structure, and functions of a part as materially to modify its nutritive and secretory activity, and then it becomes truly a disease. Under these circumstances the part is often said to be in a state of " chronic irritation." The symptoms that characterize determination of blood to a part, are those that we should expect to result from an increased quantity of blood rushin* with increased velocity through the affected textures. There is redness of a bright scarlet hue, swelling from turgescence of the vessels, heat cognizable to the surgeon as well as to the patient, a feeling of fulness and of throbbing, with an increase in the quantity of the secretions of the part; in fact, alf those symptoms that characterize inflammation in its milder forms, but in a minor degree, and of a less persistent character. The effects of determination of blood, when acute, consist either of rupture of the affected vessels, and a natural relief by the hemorrhage which ensues as may happen in piles after a dose of aloes has been given ;°or, in the pour'ino- forth of the secretions of the part, if a free surface or gland, considerably augmented in quantity and deviating somewhat perhaps from their normal cha- racter, asm lachrymation after the introduction of a grain of snuff into the eye \V hen this occurs within shut serous sacs, dropsical accumulations may ensue. The more remote effects of chronic determination of blood to a part, consists in permanently increasing its nutritive activity and thus leading to induration and hypertrophy Or, determination of blood may result in true inflammation. Ihe causes of determination of blood are three-fold- First, An external irritant directly applied to a part will induce it, as when a grain of dust is blown upon the conjunctiva. Secondly, internal irritation, as an increased use of a part, will determine an increased flow of blood to it Ihus using the eyes much in microscopical investigations may produce redness watering and irntation of those organs. To this clS* of causeVmay be rrfer d the various forms of normal determination. * lbltiIIt;u anJther^ ^ °f CaUS6S C°QSiStS " ^ rePercussion of bl°°d from one part to The treatment of determination of blood is nearly identical with that of the mi der forms of inflammation; hence we shall reserve the co^ration of it until we come to treat of that disease. consideration oi it INFLAMMATION. A'l^V^7^^ inflammatory Process is one of the most complex and difficult on which the surgeon can enter, but the labor required to masteMts INFLAMMATION. 69 details is well bestowed, inasmuch as an acquaintance with its nature, symptoms, and progress, gives an insight into a great part of the science of surgery. The management of inflammation as it affects different tissues and organs, and thus constitutes distinct diseases, comprises a great part of the duties of a surgeon. The theory of inflammation is a purely physiological and pathological study, and however interesting its investigation may be, yet as the discussion of this subject belongs rather to the domain of general pathology than to that of prac- tical surgery, it cannot consistently be entered upon here; but regarding the subject from a surgical, rather than from a physiological or pathological point of view, we must discard all hypothesis, and confine ourselves to the results of trustworthy observation. We have seen that in congestion the quantity of blood is increased, but the rate of its motion is lessened; in determination we have everything augmented, there is an increased size of the vessels, and an increased quantity of blood within them, circulating through them with increased velocity. In inflammation we have a combination of these conditions; we have an increased size of the vessels, an increase in the quantity and rapidity of the motion of the blood, but conjoined with this we have a tendency to its arrest, to its stagnation at points. In studying the phenomena of inflammation in the web of the frog's foot under the microscope, we observe that the first change on the application of a stimulus is the momentary contraction followed by dila- tation of the artery; the flow of blood through it and the capillaries is at first accelerated, retardation from congestion then ensues, and lastly, stagnation at points. At these centres of commencing stagnation, it will be seen that the blood appears to ebb and flow, oscillating to and fro, and then stopping at last; the immediate stagnation taking place in those capillaries, which are not in the direct line of passage from an artery into a vein, and the arrest taking place by the adhesion of the red corpuscles coalescing by mutual adhesion into masses, which, after being carried bodily up and down more and more slowly, at last appear to block up the vessel, partly by overcrowding and distending it, and partly by becoming adherent to its walls; this adhesion usually commencing at the angle of union between two capillaries. Around the stagnant part the vessels are crowded by an aggregation of the red cor- puscles, which appear to be more closely packed in consequence of the draining away of the liquor sanguinis. The blood does not enter the part of the vessel in which stagnation has taken place, but passes off by a collateral branch (W. Jones). At this part also, where the circulation is retarded, the white corpuscles may be seen to be increased in quantity, and appear to be adherent to the wall of the vessel, along which they are either stationary, or at most roll but languidly. Around tbe whole of this area, in the centre of which there is stagnation with retardation of the blood, there is that increased rush of an increased quantity of blood, characteristic of determination. These are the general phenomena presented by an inflamed part when studied under the microscope. In order to become acquainted with the elements of this process, we must analyze the condition of the vessels and of the blood. First, as to the Vessels: — The arteries, capillaries, and veins are all enlarged, not only in the part inflamed, but those around and leading to it, so that more blood is conveyed with greater rapidity to the seat of disease. Is this enlarge- ment of the inflamed vessels primary or not ? This would appear to depend greatly upon the stimulant that excites the inflammation, and perhaps on other circumstances that we cannot readily appreciate; thus, if a weak solution of salt, or if ice-cold water or spirit of wine be applied to the web of a frog's foot, there is a momentary constriction of the arteries and retardation of the flow of 70 INFLAMMATION. blood, followed by rapid dilatation and accelerated flow. In other cases again, as W. Jones has observed, the dilatation may be primary, no contraction pre- ceding it, as happens when a strong solution of salt or of sulphate of copper and vinum opii is applied to the part. The solid sulphate of copper produces speedy, complete, and permanent contraction. Though the vessels generally are enlarged, the arteries especially become dilated, and this dilatation implicates the afferent vessels to a considerable distance, which can be felt, by the volume of their pulsations, to be increased in bulk. That the coats of those vessels leading to the inflamed parts are dilated in consequence of being relaxed, is evident from the fact that the pulsation in them is stronger and more forcible than in other parts of the arterial system, though equally dependent upon the heart's action, to which their diminished tonicity offers less resistance. This may be readily observed in the pulsation of the digital arteries in a case of whitlow. That the vessels convey more blood through as well as to the inflamed part, is proved by the observation of Lawrence, who found that in bleeding a patient, with whitlow of one hand, in both arms, more blood flowed from the inflamed than from the sound limb, in the same space of time. In consequence of the dilatation of the smaller arteries and capillaries of the part, red corpuscles are admitted in crowds where single files could only penetrate before; hence an appearance of new vessels is presented, though none are in reality formed. It is in this way that the surface of the conjunctiva may in a few hours be brightly reddened, not by the formation of new vessels, but by dilatation and accumulation of blood in previously existing ones. Besides this dilatation of the smaller vessels of the part, the arteries become elongated, tortuous and waved, increasing in length as well as in diameter. The German pathologists — Kolliker, Hasse, and Bruch, whose views are con- firmed by Paget and W. Jones—have observed that the arteries of the inflamed part have a tendency to become dilated at points, so as to present small varicose, or aneurismal pouches projecting from their walls, or fusiform dilatations of their whole diameter. These changes would appear to arise from one of two causes; either that the vessel is constricted at points between which it main- tainsits normal width, and thus that the dilatation is apparent and not real- or that it is actually dilated where it appears to be so. ; ; I shall not enter upon the question as to the causes of these changes in the vessels; how a stimulant acts in giving rise to them, and what share the nerves of the part may have in their production; as these are points out of the scope of this work, and which, indeed, appear as yet to be altogether undecided _ The changes that the blood undergoes in inflammation are fully of as ffreat importance as those presented by the vessels. „ The most apparent physical change met with in this fluid, is, that it appears* to have become thinner, as was long ago pointed out by Hewson. But there are other changes that can only be appreciated by chemical and microscopical research. These we must study as they affect the different constituents of the blood. _ The red particles have been shown by Andral and Gavarret to be increased in quantity in the early stages of inflammation, but as the disease continues, they speedily-diminish in number; falhng below the natural standard in this respect as A\ . Jones and himon have pointed out. No other apparent change takes place in these particles, except the tendency to their a that will be noticed Ind Zc\I ,}' th t^1S n°? ft*0 the Patlent Unless the vesseI be «* down upon and tied at the part injured. Ihis must always be done at any period after the 1 " Principles of Surgery," vol. i. pp. 350, 390. 8vo. edit. TREATMENT OF WOUNDED ARTERIES. 165 receipt of the injury, so long as there is an external wound communicating with the artery. An operation of this kind is often attended with the greatest difficulty, not only owing to the hemorrhage that usually accompanies it and obscures the parts, but also in consequence of the altered condition of the tissues in the wound. In order to moderate the hemorrhage, the pressure of an assistant's fingers on the artery high up in the limb must not be trusted to; but a tourniquet should be applied so as completely to arrest the circulation through the limb, and thus to facilitate the search for exposure of the injured vessel, the wound being dry. A large probe should then be passed to the bottom of the wound, and, taking this as the centre, a free incision should be made in such a direction as may best lay open the cavity with the least injury to the muscles and other soft parts. After turning out any coagula contained within it, and clearing it as well as possible, the wounded vessel must be sought for. The situation of this may sometimes be ascertained at once by the gaping of the cut in its coats. In many cases, however, it is necessary to relax the pressure upon the artery, so as to allow a jet of blood to escape, that may indicate the position of the aperture. The ligature may then be applied by passing an aneurism needle under the vessel, if it be partially divided; or, if it be completely cut across, by drawing forwards the end and ligaturing it, as in an open wound. In doing this, care must be taken that the ligature be really applied to the vessel, and that a portion of the sheath infiltrated with blood, or thickened by adherent coagulum, be not mistaken for the artery. The incisions down to the wounded artery should be made on the side of the wound itself, and through the wound in the soft tissues covering it. Guthrie advises, that in those cases in which the wound passes indirectly to the principal artery from the back or outside of the limb, the surgeon need not follow the track of the wound, but may cut down on the vessel where nearest the surface, and then, passing a probe through the wound, the spot at which the artery has probably been wounded will be pointed out, which must then be ligatured in the usual way. No operation should be undertaken unless the hemorrhage be actually continuing. If the bleeding have been arrested, however furious it may have been, the surgeon should never go in search of the wounded vessel, or undertake any operation, unless it burst forth again. A man was brought to the University College Hospital with a deep stab in the groin directly in the course of the external iliac artery; a very large quantity of arterial blood had been lost, but the hemorrhage ceased on his admission, by the application of pressure, etc. From the great and sudden loss of blood, it was supposed that the external iliac had been punctured, but it was not thought advisable to perform any operation unless hemorrhage recurred. The bleeding did not return, the wound healing without any further trouble. 2nd. The second great principle in the treatment of wounded arteries is, that the ligature should be applied to both ends of the vessel, if it be cut completely across, or on both sides of the aperture in it, if it be only partially divided. The reason for this rule of practice is founded on physiological grounds as well as on practical experience. If the anastomoses of the part be very free, as in the arteries of the palm or fore-arm, bleeding may continue from the distal end uninterrupted by the ligature on the proximal side of the wound. If less free, it will probably issue in a stream of dark venous-looking blood in the course of two or three days. After the collateral circulation has been sufficiently estab- lished, bright scarlet blood will burst forth from the distal aperture. Expe- rience has shown that it is in this way that secondary hemorrhage from wounded arteries commonly occurs, the bleeding coming from the distal and not from the proximal end of the vessel. In some cases the distal end is so retracted and covered in by surrounding parts, that it cannot be found to be ligatured. Under these circumstances the best practice has resulted by plugging the wound from the bottom with a graduated sponge compress. 166 INJURIES OF ARTERIES. Although advocating strongly the importance of the distal as well as the proximal ligature in all cases of wounded artery, I am aware that instances are on record in which the proximal ligature alone, and that even at a distance from the wound, has proved successful in arresting the hemorrhage; but I cannot do otherwise than regard these cases as accidentally successful, the distal end having been better plugged than usual with coagulum; and I am strongly of opinion that the rule of practice should be that which is laid down by John Bell, and so forcibly and copiously illustrated by Mr. Guthrie, viz.:—That both ends of a wounded artery be sought for, and tied in the wound itself. TRAUMATIC ANEURISMS. We have hitherto discussed the treatment of an injured artery having an open wound communicating with it. It often happens, however, that the case is not so simple as has been described, but that in addition to the wound in the vessel, we have a subcutaneous extravasation of blood with more or less pulsa- tion, thrill, and bruit, from the projection into it of the blood from the wounded vessel. These traumatic aneurisms are of two kinds, the diffused and the circumscribed. 1st. The diffused traumatic aneurism consists of an effusion of blood poured out by, and communicating with the wounded artery; limited in extent by the pressure of surrounding parts, and partially coagulating 'in the meshes of the broken down cellular tissue. Its boundary, which is ill defined, is composed partly of this coagulum, and partly of plastic matter, effused by the tissues into which it is poured out, and has a constant tendency to extend by the pressure of the fluid blood, which continues to be projected into the centre of the tumor. This form of traumatic aneurism is indicated by a subcutaneous, soft, and fluctuating tumor, often of considerable size, composed of extravasated blood. At first the skin covering it is of its natural color, but it gradually becomes bluish, and is thinned by the pressure to which it is subjected. If the wound in the vessel be rather large and free, there will be a distinct pulsation in the tumor synchronous with the beat of the heart, accompanied by a thrilling, purring, or jarring sensation, and often a distinct and loud bruit. In other cases, again, if the injured artery be small, or if the wound in it be oblique, and of limited size, there will be no distinct pulsation or bruit; the tumor being either indolent and semi-fluctuating, or having an impulse communicated to it by the subjacent artery. These tumors, if left to themselves, never undergo spontaneous cure, but they either increase in size until the integument covering them sloughs and ruptures, or the external wound which had been temporarily plugged by coagulum, gives way; or else they inflame and suppurate, pointing at last like an abscess, and when bursting, giving rise to a sudden gush of blood, which may at once, or by its rapid recurrence, prove fatal. In some cases, a subcutaneous breach is made in the coagulated and plastic boundary, and the blood becoming infiltrated into the cellular tissue of the limb or part, gives rise to syncope, gangrene, and death. The treatment of these cases must be conducted on precisely the same plan as that of an injured artery communicating with an external wound, the only difference being, that in the case of the diffused traumatic aneurism, the aper- ture in the artery opens into an extravasation of blood instead of upon the surface. We must especially be upon our guard not to be led away by the term aneurism that has been applied to these cases, and not to treat such a condition, resulting from wound, by the means that we employ with success in the management of that disease. In a pathological aneurism the blood is contained within a sac, which, as will hereafter be shown, is essential for the occurrence of those TRAUMATIC ANEURISMS. 167 changes that are necessary for the cure of the disease. In the diffused trau- matic aneurism there is no sac, properly speaking, and hence these changes to which a sac is necessary, cannot take place. I doubt whether there is a case on record in which the Hunterian operation for aneurism, applied to the condition now under consideration, has not terminated in danger or death to the patient, and in disappointment to the surgeon. The proper treatment of these cases consists in laying open the tumor by a stroke of the scalpel, removing the coagula, dissecting out the artery, and liga- turing it above and below the wound in it. This operation, easy in description, is most difficult and tedious in practice. The bleeding is often profuse, the cavity that is laid open is large, ragged, and partially filled with coagula. It is with much difficulty often that the artery is found under cover of these, and in the midst of infiltrated and disorganized tissues, and when found it is not always easy to get a ligature to hold. In performing this operation, the artery must, if possible, be compressed between the tumor and the heart; if it cannot be so commanded, the surgeon must be ready to apply his finger to the wound in the artery at the moment that the sac is laid open, in order to arrest the gush of blood that takes place from the open orifice. The application of a ligature to the distal end of the vessel, if completely divided, is especially difficult. Here the application of the actual cautery, or pressure, by means of a sponge- tent, or graduated compress, will be found the best means of arresting the hemorrhage. 2nd. The circumscribed traumatic aneurism differs entirely from the diffused in its pathology and treatment, inasmuch as it possesses a distinct sac. There are two varieties of this form of aneurism; in the first, a puncture is made in an artery, or the vessel is ruptured subcutaneously, as perhaps in the reduction of an old dislocation, an extravasation of blood takes place into the tissues in the neighborhood of the wound, and if there is an external aperture, this cicatrizes. The blood that is extravasated becomes surrounded and limited by a dense layer of plastic matter poured out into the areolae of the neighbor- ing tissues, and forming a distinct circumscribed sac, which is soon lined by layers of fibrine deposited from the blood that passes through it. This tumor, usually of moderate size, and of tolerably firm consistence, pulsates syn- chronously with the beat of the heart, and has a distinct bruit, both of which cease when the artery leading to it is compressed. This form of circum- scribed traumatic aneurism most commonly occurs from punctured wounds of small arteries, as the temporal, plantar, palmar, radial, and ulnar. The treatment to be adopted depends upon the size and situation of the artery with which the tumor Fig. 73. is connected. If the artery be small, and so situated that it can be opened without much after-inconve- nience to the patient, as on the temple or in the fore-arm, it should be laid open, the coagula turned out, and the vessel ligatured above and below the wound in it. If the tumor be so situated, as in the palm, that it would be difficult and hazardous to the integrity of the patient's hand to lay it open, the Hunterian operation for aneurism should be per- formed, as was successfully done in the case (Fig. 73) in which the brachial was ligatured for an aneu- rism of this kind in the ball of the thumb, follow- ing serious injury to the hand from a powder-flask explosion. It is but rarely that this form of traumatic aneu- rism is connected with a large artery; when it is, the vessel may be ligatured above, but close to the sac, in the same way as in the 168 INJURIES OF ARTERIES. next variety. If this form of traumatic aneurism have increased greatly in bulk, so that the skin becomes thin and discolored, or inflammation ensues, and symptoms of impending suppuration take place around it, then it would be use- less to ligature the artery above the tumor, as this would certainly give way, and secondary hemorrhage ensue. Here the proper course is to lay open the sac, turn out the contents, and ligature the artery above and below the part that is wounded. The next form of circumscribed traumatic aneurism is of rare occurrence, and usually arises from a small puncture in a large artery, as the axillary or the carotid. This bleeds freely, but the hemorrhage being arrested by pressure, the external wound and that in the artery close. The cicatrix in the artery gradually yields, forming, at the end of weeks or months, a tumor which enlarges, dilates, and pulsates eccentrically, with distinct bruit, having all the symptoms that characterize an aneurism from disease, and having a sac formed by the outer coat and sheath of the vessel. It is at first soft and compressible on being squeezed, but becomes harder and firmer, and cannot be so lessened after a time. It consists of a distinct circumscribed sac, formed by the dilatation of the cica- trix in the external coat and sheath of the artery, no blood being effused into the surrounding tissues. The treatment in these cases consists of the ligature or compression of the artery leading to the sac, in accordance with the princi- ples that guide us in the treatment of aneurism from disease; though from the healthy state of the coats of the vessel, the artery may be ligatured as near as possible to the sac. ARTERIO-VENOUS WOUNDS. The wound in the artery may communicate with a corresponding one in a con- tiguous vein, giving rise to two distinct forms of disease — aneurismal varix and varicose aneurism. These preternatural communications, which were first noticed and accurately described by W. Hunter, most commonly happen at the bend of the arm, as a consequence of the puncture of the brachial artery in bleeding, but they have been met with in every part of the body in which an artery and vein lie in close juxta-position, having been found to occur as a con- sequence of wounds of the subclavian, radial, carotid, temporal, iliac, femoral, popliteal, and tibial arteries. The two forms of disease to which the preter- natural communication between arteries and veins give rise, differ so completely in their nature, symptoms, effects, and treatment, that a separate consideration of each is required. 1st. Aneurismal varix results when a contiguous artery and vein having been perforated, adhesion takes place between the two vessels at the seat of injury, the communication between them continuing pervious, and a portion of the arte- rial blood being projected directly into the veins at each beat of the pulse. Opposite to the aperture of communication between the two vessels, which is always rounded and smooth, the vein will be found to be dilated into a fusiform pouch, with thickened coats. The veins of the part generally are considerably enlarged, somewhat nodulated, tortuous, and thickened. The artery above the wound is dilated ; below it is. usually somewhat contracted. These pathological conditions are evidently referable to a certain quantity of the arterial blood finding its way into the vein, and distending and irritating it by its presence and pressure, and less consequently being conveyed by the lower portion of the artery. The symptoms consist of a tumor at the seat of injury, which can be emptied by pressure upon the artery leading to it, or by compressing its walls. If sub- cutaneous, this tumor is of a blue or purple color, of an oblong shape, and will be seen to receive the dilated and tortuous veins. It will be found to pulsate distinctly with a tremulous jarring motion, rather than a distinct impulse. VARICOSE ANEURISM. 169 Auscultation detects in it a loud and blowing, whiffing, rasping or hissing sound, usually of a peculiarly harsh character. This sound has very aptly been com- pared by Porter, to the noise made by a fly in a paper bag, and by Liston, to the sound of distant and complicated machinery. The thrill and sound are more distinct in the upper than in the lower part of the limb, and are most per- ceptible if it be allowed to hang down so as to become congested. Besides these local symptoms, there is usually some muscular weakness and diminution in the temperature of the part supplied by the injured artery. As this condition, when once formed, is stationary, all operative interference should be avoided, an elastic bandage merely being applied. Should a case occur in which more than this is required, the artery must be cut down upon and ligatured on either side of the wound in it. 2d. Varicose Aneurism. — In this case the opening in the artery and vein do not directly communicate (see Figs. 75 and 77), but an aneurismal sac is formed between the two vessels into which the blood is poured before passing into the vein. The pathological condition of this form of injury consists of a circumscribed false aneurism, communicating on one side with the artery, and on the other with the vein which is always in a state of varix, as represented in the annexed cuts from drawings of Sir C. Bell's, in the Museum of University College, re- presenting a varicose aneurism before and after it has been opened (Figs. 74 to 76). In this case there appears to have been a high division of the brachial and a communicating branch below the wound, between the radial and ulnar, in consequence of which, as Mr. Shaw informs me, the tumor pulsated as forcibly after the operation as before, the blood finding its way back through the aneu- rism into the veins, caused gangrene of the hand and arm. Fig. 74. In the symptoms of varicose aneurism, we have a combination of the characters of aneurismal varix, and of the circumscribed traumatic aneurism; there is a pulsating tumor, at first soft and compres- Fig. 75. sible, but after a time, as- suming a more solid con- sistence, in consequence of the deposition of fibrine within it; above this tumor, the vein that has been punc- W. mlWi^^^fW <&jm&B ^*y*i tured is dilated into a fusi- form pouch, presenting the ordinary characters of va- rix. The sounds heard in these tumors are of two distinct kinds: there is the peculiar buzzing thrill that always exists where there is a preternatural communication between an 170 INJURIES OF ARTERIES. artery and vein; besides this, there is a blowing or bellows sound dependent on the aneurismal disease. These signs are most perceptible when the limb is Fig. 76. in a dependent position, and the sounds can often be heard in the veins at a considerable distance from the seat of injury. There is also some impairment in the nutrition and temperature of the parts supplied by the injured vessels. As the disease advances, the aneurismal tumor lying between the artery and vein continues to increase in size, and to become hardened by the deposition of laminated fibrine. If left to itself, it would probably continue to enlarge until sloughing of the integuments covering it, followed by hemorrhage, took place. In some cases, the aperture of communication between the vein and sac becomes closed, and the aneurism is converted into one of the false, circum- scribed variety. The treatment of this disease must be conducted on different principles from those that have been laid down Fig. 77. as required in the ordinary cir- cumscribed traumatic aneurism; the difference depending upon the fact, that in the varicose aneurism there is always a double aperture in the sac, and that thus the proper deposition of lami- nated fibrine necessary for its oc- clusion cannot take place. The sac of such an aneurism may be compared to one that has been ruptured, or accidentally opened, in which we could consequently not expect the occurrence of those changes that are necessary for the cure of aneurism by the Hunterian operation. In a varicose aneurism, consequently, the sac must be freely incised, and the artery tied on either side of the puncture in it. Now this procedure may, unless the surgeon be careful, and properly understand the pathology of this disease, be attended by some difficulty. (Fig. 77.) After the first incision has been made through the integuments, the dilated vein will be laid open, and an aperture will be seen at the bottom of the vessel, from which arterial blood may be made to issue. If an attempt be made to find the artery immediately below this aperture, the surgeon will be disappointed, for the sac of the circumscribed aneurism intervenes between the two vessels. That this aperture leads into the sac, and not into the artery, may readily be ascertained by introducing a Note.—Figs. 74 and 75 represent a varicose aneurism at the bend of the arm unopened. Figs. 76 and 77, the same tumor laid open, showing the circumscribed false aneurism between the two vessels. SECONDARY HEMORRHAGE. 171 probe into it, which will be seen to be capable of being carried sideways, as well as upwards and downwards, to a considerable extent, and in dift'erent directions, altogether out of the course of the artery. In order to expose this vessel properly, a probe-pointed bistoury must be introduced into this opening, and the sac of the false aneurism slit up to its full extent, the coagula turned out, and the puncture in the artery sought for at the bottom of the cavity that has been exposed; this may now readily be made visible by the escape of a jet of arterial blood on relaxing the pressure on the upper part of the artery; a ligature must then be passed above and below the wound, and the cavity lightly dressed with lint. ACCIDENTS AFTER LIGATURE. The accidents that may follow the application of the ligature to wounded arteries are, secondary hemorrhage, and gangrene of the limb. By Secondary or Recurrent Hemorrhage, is meant bleeding from any cause after the application of a ligature. This accident may arise from a variety of circumstances, which may be divided into two great classes: — 1st, those that are dependent upon the vessel or ligature; and 2d, those that are connected with some morbid condition of the constitution or of the blood, in consequence of which those changes which are necessary for the occlusion of the artery do not take place. Amongst the first class of causes may be mentioned any imperfection in the application of the ligature; as, for instance, its being tied too loosely, or with the inclusion of a portion of nerve, vein, or muscle; so also the accidental puncture of the artery above the point to which the ligature is applied. The rush of blood through a neighboring trunk, or collateral branch imme- diately above the ligature, has been considered as likely to interfere with the formation of the internal plug; but too much importance should not be attached to this, for Porter has tied the carotid successfully within one-eighth of an inch of the brachio-cephalic artery. Bellingham has ligatured the external iliac close to its origin; and Key, the subclavian in the vicinity of a large branch, without secondary hemorrhage ensuing. I think, however, that the presence of a collateral branch in close proximity to the distal side of the ligature — more especially if it be one that serves to carry on the anastomosing circulation — will be found to have a decided tendency in preventing the formation of an internal coagulum. The wound of a collateral branch immediately above the ligature, though it do not give rise to troublesome hemorrhage at the time, will, as I have seen, cause furious bleeding as the collateral circulation becomes established. A diseased state of the coats of the artery at the point deligated, will occasion rapid sloughing and unhealthy ulceration of the vessel; those plastic changes which are necessary for its occlusion not going on within it. It has happened that fatal secondary hemorrhage has occurred from a large artery, such as the femoral, in consequence of a small atheromatous or calcareous patch having given way immediately above the ligature a day or two after its application. The constitutional causes of secondary hemorrhage act by preventing the formation of a clot within, and the deposit of plastic matter without, the artery; or if formed, causing their absorption in a few days. (Figs. 70 and 71.) Amongst the most common of these causes are those unhealthy states of the system in which inflammation of a diffused or erysipelatous character sets in, which is incompatible with plastic effusion. In these cases either no internal coagulum at all is formed, or if any is deposited it is weak, imperfect, and unable to resist the impulse of the blood; or if it have already formed, it speedily becomes absorbed or disintegrated, offering no resistance to the impulse of the blood, and being washed away. The occurrence of erysipelas, phlebitis, or sloughing of the stump or wound, 172 INJURIES OF ARTERIES. will prevent or arrest the necessary adhesive inflammation. Besides these conditions, there are certain states of the blood in which from disease, as albuminuria, it has lost its plasticity, and cannot yield the products of adhesive inflammation. Secondary hemorrhage is especially apt to occur in cases of pyemia, provided that disease assume a somewhat chronic character. The con- ditions of the blood in pyemia being incompatible with the formation of a firm and plastic coagulum within the artery, the vessel continues or becomes open, and secondary hemorrhage will certainly occur. The occurrence of secondary hemorrhage is usually somewhat gradual, and not without warning. The blood does not burst forth in a gush at once, but appears at first in a small quantity oozing out of the wound and staining the dressings; it may then cease to flow for a time, but breaks out again in the course of a few hours, welling-up freely in the wound, and either draining the patient by repeated losses, attended by the phenomena that characterize hemorrhagic fever, or else exhausting him so that he falls a victim to some asthenic disease, such as pneumonia, erysipelas, or phlebitis. In other cases again, after a few warnings, it may burst out in a gushing stream that at once destroys life. The opportunities that I have had of examining the state of the vessels in several cases of fatal secondary hemorrhage, lead me fully to concur with Guthrie and Porter, that the blood in the great majority of instances comes from the distal, and not from the proximal, side of the wound. The greater tendency in the distal end of the vessel to bleed, appears to arise partly from the less perfect occlusion of this portion of the artery, and partly from its greater liability to slough, in consequence of the ligature interrupting its supply of blood through the vasa-vasorum. It is no objection to this opinion that the fatal hemorrhage is often of an arterial character; for, though it is true that the blood which is carried to the distal end, is, for the first few days after the application of a ligature, of a venous hue; yet after the collateral circulation is once established, it gradually assumes a more scarlet tint, and at last becomes completely arterialized. Secondary hemorrhage may come on at any time between the application of the ligature and the closure of the wound. There are, however, three periods at which it is particularly apt to occur: — lstly, a few days after the ligature has been applied; 2dly, about the period of the separation of the ligature; and 3dly, at an indefinite time after its separation. The hemorrhage which occurs a few days after the application of the ligature, arises, either from some imperfection in the tying of the ligature; from disease in the arterial coats, causing them to give way; or from want of adhesive inflammation on the face of a stump: when from the latter cause, there is a general oozing or dribbling of blood from many points of the surface rather than a gush from one orifice. In those cases in which the artery has been tied above the wound only, hemorrhage is very apt to occur at this time. When hemorrhage occurs about the time of the separation of the li-ature, it may arise from any of the causes already specified that interfere with the due formation of an internal coagulum, or that occasion sloughing of the coats of the vessel. Lastly in some cases in which the ligature has separated, but the wound has remained open, the hemorrhage may take place either from the cicatrix in the artery being too weak to support the impulse of the blood; or from the coagulum being obsorbed in the way already mentioned. The continuance of the open state of the wound after the separation of the ligature, is, I think, not impro- bably dependent upon a morbid condition of the coats of the vessel, which eventually leads to hemorrhage. The length of time that will sometimes elapse between the separation of the ligature and the occurrence of hemorrhage is very remarkable thus there is a preparation in St. Thomas's Hospital of a carotid SECONDARY HEMORRHAGE. 173 artery from which secondary hemorrhage took place in the tenth week after ligature; and South mentions a case of ligature of the subclavian, in which the thread separated on the twenty-seventh day, the fatal hemorrhage occurring in the thirteenth week. The Treatment of Secondary Hemorrhage must be considered, as the bleed- ing takes place; lstly, from a stump; — and 2dly, from an artery tied in its continuity. In all cases of ligature of arteries, care should of course be taken to prevent, if possible, this accident, by keeping the patient perfectly quiet, giving no stimulants, having the bowels kept open, and the secretions free, and avoiding any undue traction on the ligature itself. lstly, The treatment of secondary hemorrhage from a stump will depend in a great measure on the degree of union that has taken place between the flaps. When the hemorrhage occurs a few days after amputation, if there be but slight oozing, elevating the part, applying cold, and bandaging it with a roller, so as to compress the flaps, will sometimes arrest the bleeding. If it continue, however, or become more severe, the flaps which will have been disunited by the effusion of blood, must be separated, and the bleeding vessels sought for and tied. In some cases the ligatures will not hold; under these circumstances the application of the actual cautery will arrest the flow of blood. If the oozing appear to be pretty general from a number of points, the flaps being somewhat spongy, I have succeeded in arresting the hemorrhage by clearing their surfaces thoroughly of all coagula, and then bringing them tightly together by means of a roller. If the hemorrhage occur at a later period, after the eighth or tenth day, when tolerable union has taken place, and appears to proceed from the principal artery of the part, an effort may be made to arrest it by the application of the horse-shoe tourniquet, which occasionally will stop all further loss of blood; or, if the union that had taken place between the flaps has been broken through, the stump may be fairly opened up, the coagula turned out, and the bleeding vessel sought for and tied. If, however, several weeks have elapsed, or if, notwithstanding the hemorrhage, the union between the flaps continues sound and firm, then the choice lies between ligaturing the artery in the stump itself, by making a fresh incision, or continuing the old one up; or else in ligaturing the artery at some distance above the stump. I prefer the former method, as in this way the surgeon is led directly to the open and bleeding vessel, and the patient escapes the dangers of a second formal operation. But if this cannot be done, it will be necessary to tie the main artery of the limb just above the flaps, or wherever it can be most readily reached; thus, in amputa- tion of the leg, the superficial femoral may be ligatured; after removal of a thigh, the same artery, or the external iliac; and in disarticulation of the arm at the shoulder-joint, the subclavian artery must be tied, either above or just below the clavicle. 2dly. When the hemorrhage occurs after a ligature has been applied to the continuity of the vessel, whether for injury or disease, pressure must first be tried. With this view the wound should be plugged, and a graduated compress should be very firmly and carefully applied by means of a ring tourniquet over the point from which the blood proceeds, which in this way may occasionally be stopped. Not unfrequently, however, this will prove ineffectual, the bleeding recurring from underneath it. When this is the case, what course should the surgeon pursue ? He may re-apply the compress once more with great care, after clearing away coagula, and drying the parts thoroughly; but should it again fail in arresting the bleeding, it is useless to trust to it again, as the hemorrhage will certainly recur, and valuable time and much blood will be lost in these fruitless attempts at checking it. The course that the surgeon should pursue in such a case as this, is a most anxious consideration, but one on which 174 INJURIES OF ARTERIES. his mind snould be clearly and decidedly determined, as there is but little time for reflection or consultation, and none for referring to authorities. ^ If the artery be situated on the trunk, as the subclavian, carotid, or one of the iliacs, there is nothing to be done but to trust to the plugging of the wound, and in the great majority of these cases the patient will die exhausted by re- peated hemorrhage. When the artery is situated in one of the limbs, more efficient procedures may be had recourse to. If it be one of the arteries of the upper extremity, the wound should be opened up, and an attempt made to tie both ends of the vessel again in this; should this fail, or not be practicable, the artery must be deligated at a higher point than that at which it had been previously tied; should the hemorrhage still continue, or be re-established, amputation is the only resource left. In the lower extremity, the treatment of this form of secondary hemorrhage renders the case replete with difficulty. Here I believe it to be useless to tie the artery at a higher point than that to which the ligature has been already applied, as gangrene invariably follows this double ligature of the arteries of the lower extremity: at least in the two or three cases that I have seen in which this practice has been had recourse to, mortification of the limb has ensued; and in all the reported cases with which I am acquainted, a similar result has occurred. Under these circumstances, therefore, I should be dis- posed to recommend the surgeon to cut down on the bleeding part of the vessel, treating it as a wounded artery, and applying a ligature above and below the part already deligated; an operation that would necessarily be fraught with difficulty. Should this be impracticable, or not succeed in checking the hemorrhage, I think that we should best consult the safety of the patient by amputating at once on a level with the ligature. Although this is a severe measure, it is infinitely preferable to allowing him to run the risk of the supervention of gangrene, which will require removal of the limb under less favorable conditions. If the hemorrhage occur from a wounded artery, to which ligatures have already been applied above and below the seat of wound, the same treatment must be adopted as in those cases in which the bleeding takes place from the application of the ligature to the continuity of the vessel. GANGRENE FOLLOWING LIGATURE. After the ligature of the main artery of a limb, the collateral circulation is, under all ordinary circumstances, sufficient to maintain the vitality of the part supplied by the deligated vessel. In some cases, however, it happens that the condition of the circulation in the parts below the ligature is not compatible with their life. The occurrence of gangrene in this way is influenced by the age of the patient, the seat of the operation, and the various conditions in which the limb may afterwards be placed. The influence of age is not, however, so marked as might be supposed; for although there can be no doubt that there is a less accommodating power in the arterial system to varying quantities of blood at an advanced period of life, and that, there would be greater difficulty in maintaining the vitality of the limb after ligature of the artery in a man of sixty than in one of twenty-five; yet I find, that of thirty cases in which gangrene of the lower extremity fol- lowed the ligature either of the external iliac or femoral arteries, that the average age of the patient was thirty-five years, as nearly as possible the mean age at which these operations, according to Norris's Tables, are generally per- formed. Of these cases of gangrene, 2 occurred under twenty years of age, 11 between twenty and thirty, 8 between thirty and forty, and 9 above forty. The seat of the operation influences greatly the liability to gangrene, which ia GANGRENE FOLLOWING LIGATURE. 175 much more frequent after the ligature of the arteries in the lower, than in the upper extremity. Besides these predisposing causes, gangrene after ligature may be directly occasioned by a deficient supply of arterial blood. In some cases this may arise from the collateral vessels being unable, in consequence of the rigidity of their coats, to accommodate themselves to the increased quantity of blood they are required to transmit; or they may be com- pressed in such a way by extravasation as to be materially lessened in their capacity. In other instances again, the existence of cardiac disease may inter- fere with the proper supply of blood to the part. Great loss of blood, either in consequence of secondary hemorrhage, or in any other way, before or after the application of the ligature, is often followed by gangrene, and is almost certain to be attended by this result if a second ligature has been applied to a higher point in the lower extremity. That a diminution in the quantity of blood circulating in the system may, under the most favorable circumstances, become a cause of gangrene after the ligature of the artery, is illustrated by the statement of Hodgson, that soon after the introduction of the Hunterian operation into Paris, it was the custom to employ repeated venesection in the cases operated on, the consequence of which was that mortification was of frequent occurrence. A more common cause of gangrene is the difficulty experienced by the venous blood in its return from the limb. This difficulty always exists even when no mechanical obstacle impedes its return, being dependent on the want of a proper vis d tergo influence to drive it on. The propulsive power of the heart, which is the main agent in the venous circulation, is greatly diminished by being transmitted through the narrow and tortuous channels of the anasto- mosing vessels. This difficulty to the onward passage of the venous blood may, if there exist any cause of obstruction in the larger venous trunks, be readily increased to such an extent as to choke the collateral circulation, and so cause the limb to mortify. This mechanical obstacle may be dependent upon the oc- clusion of the vein by inflammation excited within it opposite the ligature, by its transfixion with the aneurism needle, or by its accidental wound with the knife in exposing the artery. When such an injury, followed by inflammation, is inflicted on a vein, which, like the femoral, returns the great mass of blood from a limb, gangrene is the inevitable result. The supervention of erysipelas in the limb after the application of the liga- ture, though fortunately not of very frequent occurrence, is a source of con- siderable danger, being very apt to give rise to gangrene by the tension of the parts obstructing the anastomosing circulation I have in this way, on two occasions, seen gangrene of the fingers follow the ligature of the vessels of the forearm. The abstraction of heat from the limb, either directly by the application of cold, or indirectly, by the neglect of sufficient precaution to keep up the tem- perature of the part, often occasions gangrene: thus Sir A. Cooper has seen mortification follow the application of cold lead lotion, to a limb in which the femoral artery has been tied; and Hodgson has witnessed the same result when the operation was performed at an inclement season of the year. The incautious application of heat may, by over-stimulating the returning circulation of the limb, especially about that period when the rising tempera- ture is an indication of increased action in the capillary vessels, occasion mor- tification. In this way the application of hot bricks and bottles to the feet have given rise to sloughing; and Liston was compelled to amputate the thigh after ligature of the femoral artery, for gangrene, induced by fomenting the limb with hot water. The application of a bandage, even though very cautiously made, is apt to induce sloughing and gangrene. I have seen this happen when a roller was 176 WOUNDS OF SPECIAL ARTERIES. applied to the leg after ligature of the femoral, with a view of removing the oedema. The period of supervention of gangrene of the limb extends over the first three or four weeks after the ligature of the vessel. It seldom sets in before the third day, but most frequently happens before the tenth. The gangrene from ligature of an artery is almost invariably of the moist kind, on account of the implication of the veins. The limb first becomes cedematous. vesications then form, and it assumes a purplish or greenish black tint, rapidly extending up to the seat of operation. In some cases, though they are rare, simple mummification of the limb comes on, the skin assuming a dull yellowish-white hue, mottled by the streaks that correspond to the veins, and becoming dry, horny, and shrivelled,, about the extensor tendons of the instep. Treatment of Gangrene following Ligature. — Much may be done with the view of preventing this. Thus: the limb should be elevated, wrapped up loosely in flannel or cotton wadding, and laid on its outer side after the opera- tion. If the weather be cold, hot water bottles may be put into the bed, but not in contact with the limb. Should there be any appearance of stagnation of venous blood, the plan recommended by Mr. Guthrie of employing continuous and methodical frictions in a direction upwards for twenty-four hours, so as to keep the superficial veins emptied, may be practised. When mortification has fairly set in, amputation of the limb should be had recourse to at once as the only chance of saving life, in all those cases in which the patient's constitutional powers are sufficiently strong to enable him to bear the shock of the operation. The limb should be removed at the seat of the original wound, or opposite the point at which the artery has been tied. In those cases, however, in which the gangrene follows injury of the femoral artery just below Poupart's ligament, Guthrie advises the amputation to be done below the knee, where it usually stops for a time. If the gangrene spread, with oedema or serous infiltration of the limb, the amputation should be done high up;—at the shoulder-joint, or in the upper-third of the thigh. In these cases a large number of vessels usually require ligature, having been enlarged by the collateral circulation. CHAPTER XII. WOUNDS OF SPECIAL ARTERIES. _ Carotid.—Wounds of the carotid artery, and of its primary and secondary divisions, are of more frequent occurrence in civil practice than similar injuries of any other set of arteries in the body, in consequence of the neck being so frequently the seat of suicidal attempts. The hemorrhage from wounds of the main trunk is so copious as often to be immediately fatal. In the event of a surgeon being at hand, both ends of the bleeding vessel must be at once liga- tured. In consequence of the speedy fatality of wounds of the carotid artery and of its primary branches, traumatic aneurisms are rarely met with in this situation; they do, however, occasionally occur, and the records of surgery con- tain at least five instances of this kind, in all of which the common carotid was tied, and the patient ultimately recovered. ^ Aneurismal Varix of the internal jugular vein dependent on punctures of it, or of the carotid artery, usually the result of sword-thrusts in the neck, are WOUNDS OF SUBCLAVIAN AND AXILLARY ARTERIES. 177 apparently of more frequent occurrence than traumatic aneurism in this region; probably owing to the close proximity of the vein rendering it difficult for the artery to be wounded on the outer or anterior sides, without first perforating that vessel. The symptoms presented by these cases, though offering the gene- ral characteristics of aneurismal varix, yet have several points that are worthy of special remark. The wound of the vessels was in every instance followed by the effusion of a large quantity of blood into the loose cellular tissues of the neck; the extravasation acquiring even the size of a child's head, and threaten- ing immediate suffocation. As this extravasation subsided, the ordinary cha- racters of aneurismal varix began to manifest themselves. The period at which these symptoms first made their appearance, varied somewhat in the different cases, but they always occurred within four or five days of the receipt of the injury. In none of the cases did the disease appear to shorten life, or to have occasioned any dangerous or inconvenient effects, with the exception of some difficulty in lying on the affected side, and occasional giddiness or noise in the head on stooping. Varicose aneurism does not appear to have been met with in this situation. No operation is admissible in these affections. Traumatic aneurisms of the temporal artery, and of its branches, occasionally occur as the result of partial division of these vessels in cupping on the temple; two cases of this kind I have met with, in both of which the disease was readily cured by laying the tumor open, turning out its contents, and tying the artery on either side of it. Subclavian. — A wound of the subclavian artery may almost invariably be looked upon as fatal, though in consequence of the manner in which it is pro- tected by the clavicle these injuries can scarcely occur except from gun-shot violence. From the rapidly fatal nature of wounds of the subclavian artery, traumatic aneurisms in this situation are not met with; but when the artery passes into the axilla below the margin of the first rib, they are not of unfre- quent occurrence. Aneurismal varix of the subclavian vein resulting from wound of the artery in this situation, has, however, been seen, notwithstanding the separation that exists between the two vessels until they reach the acromial angle of the subclavian space. These injuries have likewise usually been the result of sword-thrusts, and do not admit of any surgical interference. Axillary.—In open wounds of the axillary artery, and of its branches, the rule of practice consists, in cutting down upon the bleeding vessel wherever it may be situated, and ligaturing it on either side of the wound. It must be borne in mind, that the arterial branches given off between the lower edge of the first rib, and the fold of the axilla being very numerous, a punctured wound of the axilla or side of the chest may injure one of these vessels, though from its course, and the free flow of arterial blood that has followed the stab, it may be supposed that the axillary artery itself has been punctured. The particular vessel injured can only be ascertained by following up the wound and ligaturing the artery that furnishes the blood. In some cases, however, the state of the parts may be such, that it may be impossible to trace the artery at the depth at which it is situated, or even to expose it in a mere superficial situation, as in the stump after amputation at the shoulder-joint. Under these circumstances, the rule of surgery, of ligaturing an artery at the seat of injury, may be departed from, and the main trunk should be tied either above or below the clavicle; and the success of this operation has been sufficient to justify our having recourse to it rather than exhaust the patient by any prolonged attempts at the ligature of the vessel in the open wound, though I think that this ought first to be attempted. Of 15 cases in which the artery has been ligatured either above or below the clavicle, for hemorrhage from wounds in the axilla or from stumps, I find that 9 were cured and 6 died. Although the success is about equal in whichever situation the 178 WOUNDS OF SPECIAL ARTERIES. vessel be tied, I should certainly give the preference to the supra-clavicular operation, owing to the greater facility of its performance, and the comparative absence of collateral branches at the seat of ligature. In some cases, however, especially after amputations at the shoulder, the clavicle is pushed up at its acromial end, and then the artery might be best reached below the clavicle, under or through the pectoral muscles. Traumatic Aneurisms in the Axilla are not of unfrequent occurrence, arising directly from gun-shot wounds, or from the thrust of a knife, sabre, or other pointed weapon. In some cases the injury arises from a subcutaneous rupture of the vessel, the patient stretching out and straining his arm in an attempt to save himself from falling, and feeling a sudden snap in the axilla, which is followed by the formation of a rapidly diffused aneurism. There are several cases on record in which axillary aneurism has resulted from violent attempts made by the surgeon in the reduction of old standing dis- locations of the head of the humerus. Thus Pelletan mentions a case of this kind, in which the tumor being supposed to be emphysematous, was opened, and the patient perished of hemorrhage. Warren relates a case of diffused axillary aneurism resulting from rupture of the artery, in consequence of the surgeon attempting to reduce a dislocation of the humerus by using his foot as a fulcrum in the axilla, but without taking off his boot. Gibson has related three cases of axillary aneurism following rupture of the artery, in the attempt to reduce old standing dislocations with the pulleys. These cases are of much interest to the surgeon, as showing the necessity for great caution in the use of powerful extending force in the reduction of old dislocations, adhesions having probably formed between the artery and head of the bone. Some of these traumatic axillary aneurisms have a tendency to diffuse them- selves with great rapidity, filling up the whole of the hollow of the armpit, and extending under the pectorals, even up around the shoulder. In other cases again, when more circumscribed, the disease may get well spontaneously, as happened in cases recorded by Van Swieten, Sabatier, and Hodgson. In other instances again, the disease has remained stationary for years, or has even undergone spontaneous cure. It cannot however be considered sound practice to leave a traumatic aneurism of this artery without surgical interference, after the ordinary dietetic and hygienic plans of treatment have failed in effecting a cure, for it may at any time become rapidly diffused, or inflame and suppurate. The treatment of traumatic axillary aneurism must have reference not only to whether it is diffused or circumscribed; but if diffused, whether it be of recent origin, or have originated from puncture or subcutaneous rupture of the vessel. When a diffused traumatic aneurism of recent origin, rapid formation, and dependent upon puncture of the artery, is met with in the axilla, the treatment must be conducted in the same way as that of a wounded artery, without ex- travasation, in this situation. The tumor should be laid open, the artery sought for, and, if possible, ligatured where wounded. If this be impracticable, it may be deligated above the clavicle. There is, however, the danger after this operation, either of secondary hemorrhage coming on from the seat of wound, by blood conveyed through the collateral vessels, which open into the sub- scapular and circumflex arteries; or else, of the limb falling into a state of gangrene. In either case amputation at the shoulder and through the aneuris- mal extravasation is the only practice that can be had recourse to. In those cases of diffused traumatic aneurism of the axilla that arise from subcutaneous rupture of the artery, the condition of parts is essentially the same as in a case of punctured wound of the vessel, with the exception of the existence of no external aperture in the integuments. In these cases there is a tumor of considerable size, hard or fluctuating, according to the state of coagulation of its contents, with thrill, pulsation, a gushing, hot sensation, TRAUMATIC AXILLARY ANEURISMS. 179 much oedema of the arm, tendency to inflammation, suppuration, and gangrene of the sac. In such a case the choice would lie between treating the injury as that of a wounded artery, by direct incision, or ligaturing the vessel above the clavicle. The first plan, by direct incision, has never to my knowledge been practised, and would present so many difficulties as scarcely to be a justifiable procedure. The ligature of the vessel above tfie clavicle has been done three times, and of these only one recovered, two of the patients dying of gangrene and second- ary hemorrhage. In the successful case, secondary hemorrhage had occurred, and gangrene of the arm, which threatened, was prevented, and the patient saved, by having amputation at the shoulder-joint performed. Circumscribed traumatic aneurisms of the axillary artery are not uncom- monly of slow formation, existing for several months or years before they require operation, although resulting from punctured wound of the armpit. In chronic cases such as these, the aneurism is necessarily provided with a firm and distinct sac, and approaches closely in its characters to the pathological form of the disease. The treatment here cannot be conducted on the principles that guide us in the management of a wound, or of a diffused aneurism of recent occurrence of this artery; for not only is the circumscribed aneurism provided with a sac, but the vessel, at the point injured, would very probably be found to have undergone changes that would render it little able to admit or to bear the application of the ligature. It would be softened, thickened, and lacerable, with perhaps a wide funnel-shaped aperture leading into the sac, which would be closely incorporated with the neighboring parts. But indeed the treatment of this form of circumscribed traumatic aneurism by the ligature of the artery on the proximal side of the sac, has been found to be attended with remarkable success. In eight recorded cases in which this operation has been performed, not one fatal result has been noted. In all, the aneurism arose from stabs or gun-shot wounds, and had existed for various periods, between two weeks and four years. In four of the cases the artery was ligatured above, and in four below, the clavicle; and in one case of each category there was suppuration of the sac. The particular point at which the artery should be ligatured must depend upon the condition of the tumor. If this be of large size, or arise from the upper part of the axillary artery above or immediately below the pectoralis minor muscle, there is no choice but to deligate the vessel above the clavicle. Should, however, the principal increase in the tumor take place in a direction downwards and forwards under the great pectoral muscle, the portion of the artery immediately below the clavicle appearing to be free from disease, the question would arise as to whether this part might not be selected for the appli- cation of the ligature; and as the results of both operations have hitherto been equally favorable, this must rather be determined by the peculiarities in each case, than on more general grounds. Most surgeons, I think, would however prefer ligaturing the artery above the clavicle, as being a simpler proceeding, than tying it below that bone; which, moreover, has the disadvantage of bringing the scalpel into very close proximity with the sac, which, were it to stretch upwards under the pectoralis minor to a greater extent than could be discernible externally, might possibly be opened by the knife, as has even hap- pened in operating above the clavicle. It has been recommended to apply the ligature between the sac and the origins of the sub-scapular, and posterior circumflex arteries, above the former and below the latter; but this is an anatomical impossibility if the aneurism be situated above the lower border of the axilla. Compression of the artery on the distal side of the tumor has succeeded in curing the disease in a case that was under Dr. Goldsmith, of Vermont. 180 WOUNDS OF SPECIAL ARTERIES. The Brachial Artery and its Branches.—The hemorrhage from wounds of the brachial artery may sometimes be arrested by the employment of metho- dical compression, but usually it requires ligature in the ordinary way on each side of the aperture. This vessel may occasionally be the seat of traumatic aneurism, in consequence of a puncture received in venesection. This accident, which was formerly of frequent occurrence, when venesection was practised by professed phlebotomists, now very rarely happens. Should a surgeon be so unfortunate as to puncture the brachial artery in this way, he may prevent injurious after-consequences by keeping up a proper degree of pressure, by means of a graduated compress applied immediately on the occurrence of the accident. With this view, the fingers, hand, and fore-arm, having been very carefully padded and bandaged, a well-made graduated compress should be firmly applied over the seat of puncture, and retained there for at least ten days or a fortnight. Should the aperture in the artery not be closed in this way, either a circumscribed false aneurism, a varicose aneurism, or an aneu- rismal varix will form, according to its situation in relation to the vein. In the Circumscribed Traumatic Aneurism at the bend of the arm, following a wound of the brachial artery, we have the usual soft or semi-solid pulsating tumor, which can readily be emptied on pressure, and possesses more or less bruit. This disease may be treated in one of three ways : by compression upon or above the tumor; by ligaturing the artery leading to it; or by cutting through the sac, and deligating the vessel on either side of the aperture in it. The compression of the tumor has often been successfully practised. It may be done by means of a graduated compress, or the application of a ring tourniquet — the tumor becoming consolidated, and gradually undergoing absorption. Should this plan not succeed, we must be guided in our ulterior measures by the particular conditions of the case. If the tumor be of recent origin, soft and compressible; or, though of longer duration, large, with a thin sac, it should be treated by direct incision, and the artery be deligated on either side of the wound in it. Should, however, the tumor be small, or but of moderate size, and the sac be tolerably thick and firm, so as to admit of the deposit of laminated fibrine, we may treat it by deligation of the brachial artery, either in the middle of the arm, or, as Anel did with success, imme- diately above the tumor. In the event, however, of the disease not being cured in this way, incision of the sac must be had recourse to, as I have known to be necessary in a case in which the brachial artery was tied above the tumor, which was large, with a thin sac, the pulsations returning in a few days, and the tumor continuing to enlarge. Varicose Aneurism, at the bend of the arm, presents the ordinary character of the disease. ^ Occasionally, though rarely, it would appear that the aperture of communication between the aneurismal sac and the vein becomes closed, and thus the varicose is converted into the ordinary circumscribed traumatic aneurism. The treatment of this affection must be conducted on different principles from that of the ordinary circumscribed variety, for whatever be the density of the sac, it is never, as has already been explained (p. 169), a perfect one, having always an opening into the vein which would prevent its proper closure by the . deposit of laminated fibrin. In 4 cases related by Sabatier, which were treated by Anel's operation, amputation became necessary in 2, and in the other cases, the operation by incision of the sac was required before a cure could be effected. The sac must therefore be laid open, and the vessel tied on either side of it in a the way that has been recommended in the treatment of that disease, and with the caution there laid down. If the varicose aneurism be converted, after a few days, into the circumscribed form, the aperture into the vein becoming occluded, the ligature of the artery above the sac may be successfully employed, or com- pression succeed in curing the disease. WOUNDS OF THE PALMAR ARCHES. 181 In aneurismal varix of the arm, a roller and compress are all that can be required. Arteries of the Fore-arm and Palm. — These vessels are very commonly wounded by pieces of glass, earthenware, or knife-cuts. In every case the bleeding-point must be cut down upon, and both ends of the vessel tied. This rule is peculiarly imperative in this situation, on account of the freedom of the anastomosis through the palmar arches. In many of these cases the bleeding is at first very free, but, being arrested by pressure, does not break out again until eight or ten days have elapsed, when, the arm being much infiltrated with blood, inflamed, and swollen, double ligature of the vessel, at the seat of injury, has to be practised under somewhat difficult and unfavorable circumstances. Traumatic Aneurism of the Radial and Ulnar Arteries usually assumes the circumscribed form, owing to the pressure employed at the time of injury, con- fining the extravasation. If it be small and recent, and situated superficially at the lower part of the fore-arm, or if it be in any way diffused, the better plan is to cut down upon and through the tumor at once, ligaturing the vessel on either side. If, however, the aneurism be deeply seated amongst the mass of muscles at the upper part of the fore-arm, near the elbow joint, the wound having healed, and the soft parts covering it being healthy and firm, the advice given by Mr. Liston appears to be most judicious :—rather than cutting through the muscles, and detaching their connections, he recommends that the aneurism should be left to attain some consistence, and then that the brachial artery be secured in the mid-arm. Wounds of the Palmar Arches not unfrequently occur from the breaking of glass or bottles in the hand, or stabs from some pointed instrument, and are always troublesome to manage. If the surgeon see the case shortly after the infliction of the wound, he might endeavor, by enlarging the aperture to a mode- rate extent, and with due attention to the tendons and nerves of the part, to secure, the bleeding vessel. Should he fail in doing this, which he certainly would if it be the deep arch that is injured, a graduated compress must be well and firmly applied from the bottom of the wound; and that artery above the wrist which appears most to correspond with the arch wounded, or better still, the brachial itself should be compressed with a ring tourniquet, or the elbow may be forcibly flexed, and cold assiduously applied. If the case be not seen until several days have elapsed, when secondary hemorrhage has occurred, and the palm has become infiltrated and swollen, pressure can no longer be borne upon the seat of injury, and it is useless to endeavor to search for the injured vessel in the midst of sloughy and infiltrated tissues, through a narrow wound which cannot be enlarged without danger of disorganizing the hand. Under these circumstances, it is necessary to deviate from the ordinary rule of practice in wounded arteries, and both arteries should be tied, immediately above the wrist; should hemorrhage occur after this, as might happen in the case of an enlarged interosseous artery, the surgeon must try compression or ligature of the brachial. Circumscribed Traumatic Aneurism in the Palm is by no means of frequent occurrence. It may however follow wounds of the palmar arches. In such a case as this, it would be clearly out of the question to lay open the sac, and to search for the injured vessel in the midst of the aponeurotic and tendinous struc- tures of the hand. It would consequently be necessary, either to tie the radial and ulnar arteries immediately above the wrist, or to ligature the brachial in the upper arm. The latter plan should be preferred; as, were the first mode of treatment put into practice, the sac might continue to be fed by the interosseous artery, as happened in a case of Roux's, in which the patient died of hemorrhage from the palmar aneurism after the ligature of both arteries of the fore-arm. In the case represented (fig. 73), Liston successfully ligatured the brachial in the mid-arm, after compression upon it had failed to effect a cure. 182 WOUNDS OF SPECIAL ARTERIES. Femoral Artery and its Branches. — The hemorrhage from these arte- ries when wounded is always very profuse. In all cases, ligature of the wounded vessel should be practised at the seat of injury. If a diffused traumatic aneu- rism have already formed, the artery should be commanded by a tourniquet, as it passes over the brim of the pelvis, the sac laid open, and the bleeding vessel sought for and tied. Mr. Guthrie has collected a great number of cases, which prove incontestably that the general principles of treatment in wounded arteries must not be departed from, when the arteries of the groin or thigh are wounded. On the contrary, the facility with which in most cases the circulation is kept up, and the readiness with which secondary hemorrhage comes on as a conse- quence of the free anastomosis in this situation, renders the rule of practice of applying a ligature on both sides of the wound in the vessel peculiarly stringent in all recent arterial wounds in this part of the body. Secondary hemorrhage and gangrene of the limb are the great sources of danger here. When gan- grene is imminent, or has come on, amputation is necessarily the sole resource. With regard to secondary hemorrhage, supervening after ligature of the artery at the seat of injury, there is, I think, no safe course but removal of the limb Where the artery has been tied higher up, as for instance when the external iliac has been ligatured for recent wounds or traumatic aneurisms in the groin or upper part of the thigh, the hemorrhage appears to have returned, or gangrene to have supervened in all the cases. If the traumatic aneurism have assumed a circumscribed character, it must be treated on the principles laid down for this form of the disease, the supplying artery being ligatured above the tumor; and cases are not wanting in proof of the success of this practice. It occasionally, though rarely, happens that a varicose aneurism is formed in the groin or upper part of the thigh, as the result of wound of artery and vein in this situation. It usually presents the ordinary characters of this disease but some peculiarities have occasionally been met with. Thus, in a case related by Mr. Horner, there was a wavy motion in the femoral vein on the uninjured side, arising from the blood in the wounded vessel communicating a 'thrill upwards to that contained in the vena cava. In a case related by Dr Morrison it is stated that a tumor as large as the human uterus at the third month of pregnancy, communicated with the injured vein. The treatment of this disease is exceedingly unsatisfactory; of 4 cases in which the external iliac artery was tied, a fatal termination occurred in every instance 2 of the patients dying of gangrene of the limb, and the remaining 2 or secondary hemorrhage and consecutive pneumonia. It has conseauentlv been proposed by Mr. Guthrie that the tumor be laid open, and tie artery Jen above and below the aperture in it. As this plan has never been fairiy put in K?n V°J i PwapS. be US6lelS t0 SpeCulate on the chances of success of this kindTn thV J WG mUSiiGar in mind> that la?in? open an aneurism of this kind in the groin is a very different matter from adopting the same pro- cedure at the bend of the arm, or in a situation where the surgeon can^eadily command the artery on the proximal side of the sac. The guS of bloodTom o large an artery as the common femoral, would be so great, that with wliateve^ rapidity the operation were performed, there would be cons derable risk of the patient suffering a fatal hemorrhage, before the vessel mnttlS Ha• ! S is it wnnU K« Z;fk o j- , ,, ,e vessel, matted and incorporated as it would be, with surrounding parts, could be separated and secured ■ and the ligature of the vein would probably be followed by gangrene of the limb the^TrteZte W STf° ^^ ? * d^ ^, ~ni^ with the arteries of the leg and foot, require to be treated by the free exposure of the bleeding orifice in the vessel, and its inclusion between two Latures In sZlo Slf wT^ V^rf ?,the.rteH0r tibkl or PernK e y, t su geon will have to cut freely by the side of or through the muscles of the calf. This he must do in the direction of their fibres, injurint them by trans verse mcision as little as possible, and by taking the track ofXTwin? as his INJURIES OF MUSCLES AND TENDONS. 183 guide, the bleeding vessel will at last be reached, and must then be tied in the usual way. In such cases as these, surgeons have often attempted to arrest the hemorrhage by the ligature of the superficial femoral or popliteal arteries; and though they have occasionally been successful, as happened in a case in which I saw the popliteal ligatured for a wound of one of the arteries of the leg, yet I fully concur with Mr. Guthrie in deprecating this practice, as contrary to good surgery, and, with him, regard the success that has occasionally followed these operations as purely accidental. Small circumscribed aneurisms are occasionally met with in the foot, in con- sequence of the wound of one of the plantar arteries, as in operations for club-foot. If pressure have failed in preventing or curing the disease, the only course left to the surgeon is to lay the tumor open, and to ligature the artery on either side in the usual way. CHAPTER XIII. INJURIES OF MUSCLES AND TENDONS. Sprains, or strains, of muscular parts without rupture of fibre, are of very common occurrence, especially about the shoulder, hip, and loins, and are accompanied by much pain, stiffness, and inability to move the part. When occurring in rheumatic subjects, these injuries not uncommonly give rise to severe and persistent symptoms. In some cases painful atrophy, rigidity, or local paralysis of the injured muscle being induced. In the treatment of these accidents, when recent, it will be found that kneading or rubbing the part with a stimulating embrocation, the application of dry cupping, or, if the pain be severe, the abstraction of a few ounces of blood by cupping, together with rest, is most efficient. If the injury occur in a rheumatic constitution it will be found useful to give colchicum and Dover's powder in the following form: R Extr. Colchici Acetici, gr. i. Pulv. Ipecac. comp., gr. x. Extr. Coloc. comp. gr. iv., f. pil. iij. If the pain continue, the application of the "thermic hammer" is exceedingly serviceable, and if local paralysis or atrophy ensue, the use of the electro-magnetic apparatus will be beneficial. The subcutaneous rupture of muscles and tendons not unfrequently occurs, not so much from any external violence, as by the contraction of the muscle rupturing its own substance. In the majority of cases, when rupture takes place, it is the tendon that gives way, most commonly at its point of attachment to the muscle, which opposes itself, by its vital contractility, to that forcible extension which must necessarily precede its rupture. Sedillot found that in 21 cases, the rupture occurred at the point of origin of the tendon 13 times; and in the remaining 8, the muscle itself was torn. It occasionally happens that the muscular sheath is ruptured, so that the belly of the muscle forms a kind of hernial protrusion through the aperture; or the tendon may be displaced by rupture of its sheath. This usually happens with the long head of the biceps, or the extensor tendons of the fingers. These ruptures most commonly occur in middle-aged people, who have lost the elasticity of youth, though their physical strength be unimpaired. At the moment of the rupture taking place, the patient usually experiences a sudden shock, as if he had received a blow, and sometimes hears a snap. He becomes unable to use the injured limb, and at the part where the rupture has occurred 184 INJURIES TO BONES. finds a hollow or pit, produced by the retraction of the end of the torn muscle, which is contracted into a hard lump above this. These accidents, though troublesome, are seldom serious. The tendo-achillis, the quadriceps-extensor of the thigh, the triceps of the arm, the biceps, the deltoid, the rectus abdominis, are the tendons and muscles that most commonly give way, with the relative frequency of the order in which they are placed. The mode of union of these injuries has been well described by Paget. When a tendon is cut or torn across, an ill-defined mass of nucleated blastema of a greyish-pink tint is effused into the cellular tissue and sheath, between the cut ends. About the 4th or 5th day, this has become more defined, forming a distinct cord-like uniting mass between the ends of the tendon; in the course of two or three more days, this mass has become tough and filamentous; the tissue gradually perfecting itself, until it closely resembles tendinous structure, though for some time it remains dull white and more cicatrical in appearance. The strength of this bond of union is marvellously great; Paget found that the tendo-achillis of a rabbit, six days after its division, required a weight of 20 lbs. to rupture it. In ten days the breaking weight was 56 lbs. Divided muscles unite in the same way as tendons, but less quickly, and by a fibrous bond. Treatment.—The principle of treatment in these cases is extremely simple: it consists in relaxing the muscles by position, so as to approximate the divided ends; and maintaining the limb for a sufficient length of time in this position for proper union to take place. If relaxation be not attended to, the uniting bond will be elongated and weak. Stiffness and weakness are often left for a length of time—for many months, indeed—after union has taken place. Warm sea-water douches, followed by methodical friction, will greatly tend to restore the suppleness of the parts. When the tendo-achillis is ruptured, the best apparatus consists of a dog- collar placed round the thigh above the knee, from which a cord is attached to a loop in the back of a slipper; by shortening this cord, the leg is bent on the thigh, and the footextended, so that the muscles of the calf become completely relaxed. After this simple apparatus has been used for two or three weeks, the patient may be allowed to go about wearing a high-heeled shoe for some weeks longer. When partial rupture of one of the extensor muscles of the thigh takes place, the patient's limb must be kept for some little time in the same position as for fractured patella, and then he maybe allowed to walk about with a leather splint behind the knee, so as to present flexion of this joint. In muscular or tendinous ruptures of the arm, a sling is all the apparatus required, but it is especially in these injuries of the deltoid that paralysis and atrophy are apt to result. CHAPTER XIV. INJURIES TO BONES. A bone may be bruised, bent or fractured. Bruising of the bone and peri- osteum often occurs, and is usually of no great moment, but if severe, or hap- pening in bad constitutions, or in old people, it may give rise to serious conse- quences Jit «? contusion be severe the vitality of a layer, or even of the whole sub- stance of the bone, may be destroyed, as happens sometimes from the graze or FRACTURES. 185 contusion of a bullet. Even a moderate contusion of a bono that is but thinly covered, as the shin, or elbow, may give rise to troublesome symptoms from inflammation of the periosteum. In old people, the contusion of a bone is fre- quently followed by its atrophy and shortening, as happens in the neck of the femur; and in strumous constitutions, serious disease of the bone may be attri- buted to this cause. In the treatment of bruised bone, leeches and fomentations are the most important means that we possess; the after-consequences will be considered when we come to speak of necrosis. Bending of bone may occur in two conditions, with or without fracture: independent of fracture, it is most commonly met with in very young subjects, before the completion of ossification, the bone being healthy, but naturally soft at this period of life. It occasionally takes place after the adult age, but is then the result of some structural change, by which the natural firmness of the osseous tissue is diminished. The bending most commonly occurs in the long- bones, especially the clavicle, the radius, and the femur, but sometimes is met with in the flat bones, or those of the skull, in which depression takes place from a blow without fracture having occurred. In many cases of bending both of long and flat bones, there is partial fracture on the convex side. The treatment is simple: the surgeon gradually straightens the bone, by applying a splint on its concave side, towards which the bone is pressed by a bandage and a pad, applied upon its greatest convexity. FRACTURES. The management of fractures constitutes one of the commonest duties of the surgeon, and hence the consideration of all that relates to their nature and treatment is of the very utmost importance. Fractures are almost invariably the result of external violence. This may act in two ways: directly or indirectly. The worst forms of fracture are occasioned by direct external violence, the blow crushing and splintering the bone, as by the passage of a heavy wheel, or a gun-shot injury. When the bone is broken by direct violence, the fracture is always at the seat of injury, and is often complicated with considerable mis- chief to the soft parts, the result of the same force that breaks the bone. Indi- rect violence may break a bone in two ways. One that is more commonly talked of than seen is by " contre-coup," in which, when a blow is inflicted on one part, the shock that is communicated expends its violence on the opposite point, where the fracture consequently occurs. This form of injury is chiefly met with in the head; and although its occurrence has been denied, I cannot doubt it, as I have seen unequivocal instances of this kind of fracture. In the next form of indirect violence occasioning fracture, the bone is broken by being snapped, as it were, between a resisting medium on one side, and the weight of the body on the other. Thus, a person jumping from a height, and alighting on his feet, may break his legs by their being compressed between the weight of the body above and the ground below. The long bones are those that are most frequently fractured in this way, and the fracture occurs at the greatest convexity, or at their weakest point. When a person jumps from a carriage that is in motion, although the height of the fall be not great, yet its force is considerable, the body coming to the ground with the same velocity as that with which it was being carried onwar'ds in the vehicle. Hence, fractures received in this way are usually severe, and often compound or comminuted. Muscular action is not an unfrequent cause of fracture of those bones into which powerful muscles are inserted. This is especially the case with the patella and some of the bony prominences, such as the acromion, which are broken in the same way that a tendon is ruptured,— by the violent contraction 186 FRACTURES. of the muscles attached to them tearing them asunder. It is not often that the long bones are so fractured, but it has happened that the humerus has been broken by a person striking at, but not hitting another; or that the clavicle has been fractured by a rider giving his horse a back-handed blow. In these cases, however, muscular action may not have been the sole cause, the weight of the limb also tending to fracture the bone. Those bones that do not offer attachment to any powerful muscles, as the cranial, for instance, cannot.be frac- tured in this way. The predisposing causes of fracture are numerous and varied. Some bones are especially liable to be broken in consequence of their serving as points of support. Thus, when a person falls upon the hand, the shock is transmitted from the wrist-joint through the radius, humerus, and clavicle, to the trunk; the radius and clavicle being the weaker bones, are especially liable to be fractured under these circumstances. So again, the situation of a bone irrespective of use, or any other circumstance, may predispose it to fracture; the prominent position of the nasal bones, and the exposed situation of the acromion, render these parts peculiarly liable to this injury. The shape of some bones disposes them to fracture; thus, a long bone is necessarily more readily broken than a short and thick one; hence, fracture of the tibia and femur from falls on the feet are more common than of the os calcis. Certain parts of bone are more commonly fractured than others. Those points espe- cially into which powerful muscles are inserted, or that are in exposed situa- tions, and hence liable to injury, or to receive the weight of the falling body, are often broken. Hence, the acromion, the olecranon, and the neck of the femur, are commonly fractured. Age exercises considerable influence, not only on the general occurrence of fracture, but on the peculiar liability of certain bones. Though fractures may occur at all ages, even in intra-uterine life (Chaussier having dissected a foetus that had 113 fractures), yet, bone being elastic and cartilaginous in .early age, is less readily broken than when it has become brittle and earthy, as in advanced life. In children, fractures most commonly occur in the shafts of the long bones; or, at the point of junction between the shaft and epiphysis, where ossification has not as yet taken place. This separation of the epiphysis in children, the detachment as it were of the terminal points of ossification, is not unfrequently met with, and occurs chiefly at the lower end of the humerus and femur, sometimes in the radius and other bones. As age advances, the compact tissue of the shaft becomes denser and harder, but the cancellous structure of the extremities more dilated, and looser, hence fracture of the neck of the femur is especially common in old people. In young persons also, the bone is usually simply broken transversely, but fractures taking place at a more advanced period of life generally assume an oblique direction, and become comminuted; so also they more commonly extend into joints than when occurring in early age. Occasionally fracture termed " spontaneous," happens without any very direct occasioning cause, or under the influence of a degree of violence that would usually be insufficient to occasion it. This may happen in consequence of the texture of the bone being weakened or rendered more brittle by disease, such as mollifies or fragilitas ossium, by the cancerous cachexy, by syphilis, by the presence of cancerous growths within the substance of the bone itself, or by the pressure upon, and absorption of it, by some neighboring tumor. In other cases, again, it occurs without any apparent disease, local or constitutional. This usually happens as the result of the brittleness and weakening induced by age. I have known a gentleman little above fifty, apparently in perfect health, break his thigh with a loud snap whilst turning in bed. In these cases union rarely takes place, or not without much difficulty. Sex necessarily influences the liability to fracture, men being more frequently exposed to the causes of this injury than women. In women the bones that VARIETIES OF FRACTURES. 187 are most frequently fractured are the clavicle, the tibia, and the neck of the femur. In men, the shafts of the long bones, the cranium, and pelvis, are most frequently broken. From statistical accounts it would appear that the right limbs are more frequently broken than the left, being more exposed to the causes of fracture. It has been supposed that the bones are more brittle in winter, and hence break more readily than at other seasons, but this is altogether a mistake, though fractures may be common at this period of the year, from falls being more frequent. Fractures present important varieties as to their nature and their direction. The varieties as to nature depend upon the cause of the fracture, its seat, and the age of the patient. Varieties as to Nature.—Fractures are divided into two great classes, accord- ing as they are accompanied or not by an open wound. When the bone is merely broken across, the fracture is a simple one. When one fragment is wedged into another, the compact tissue being driven into the cancellous struc- ture, it is said to be impacted. When the bone is broken into several fragments, it is comminuted. When the soft parts covering the broken ends of bones are torn through, so that the fracture communicates by a wound with the surface of the body, it is said to be compound. The fracture may be rendered compound in two ways, either by the same injury that breaks the bone lacerating the soft parts, as when a bullet traverses a limb, and fractures the bone; or else by the protrusion of one of the extremities of the broken fragment through the integuments O C" o covering it; this necessarily most frequently happens when the fragments are sharp and pointed, and the coverings thin, and may be occasioned either by muscular contraction driving the fragment through the skin, or by some incau- tious movement on the part of the patient, forcing it through. A fracture is said to be complicated when the injury to the bone is conjoined with other circumstances which are perhaps of more importance than the mere fracture itself, the complication constituting perhaps the most serious part of the injury, and influencing greatly the general result of the ease. Thus, a fracture may be complicated with injury of an important internal organ, as, of the brain, lungs, or bladder; the injury to the organ being inflicted by the projection against it of one of the broken fragments. So also a fracture is not unfrequently complicated with the wound of one of the principal arteries of the part, as happens especially in the leg, where the tibial arteries, being in close contact with it, are often torn by the broken bone. In other cases, again, the fracture is associated with injury of a joint, or dislocation of it. Besides these varieties of fracture, it occasionally happens that a bone is only cracked, or partially broken. This especially occurs in the bending of bone in children, in which cases the fracture may be partial or incomplete, merely extending across the convexity of the curve made by the bone. Intra periosteal fractures have been described, but this is an anatomical refinement of little practical value. The direction assumed by fractures varies greatly, and depends materially on the cause of the injury, as well as upon the bone that is fractured. The line of fracture may run through a bone in three different directions: either transversely, obliquely, or longitudinally to its axis. The transverse fracture is the simplest, and is seldom complicated with injury to the neigh- boring parts. It chiefly occurs in children, and very frequently in the articular extremities or processes of bones; it unites readily, and is attended by but little displacement; it is most commonly the result of direct violence, but it may arise from muscular action, as in the case of the patella, which is usually broken in this way. The oblique fracture commonly occurs from indirect violence; the breaking 188 FRACTURES. force being applied to the ends, and not across the shaft. Itoften runs a long way, more than half the distance of the shaft of a bone, and is more dangerous than the transverse, owing to the obliquity of the fracture causing Fig. 78. the ends of the bone to be sharply pointed (Fig. 78, a), and thus frequently to puncture the skin, or to perforate an artery. It is tedious in its cure, owing to the fragments being less directly in apposition; hence, also, there is a greater liability to shortening of the limb; it is principally met with in the shaft of the long bones of adults, and elderly people. The longitudinal fracture consists of a splitting of a bone in the direction of its axis (fig. 78, 5), and has a great tendency to run into a joint, and to separate the articular ends of the bone. It most commonly results from gun-shot injury, especially from Minie balls, but I have seen cases of its occurrence from very slight violence. The great danger of longitudinal fractures is the implication of the neighboring articulation, but in some cases it extends a little distance up the shaft of a bone, stopping short of this. The signs of fracture, taken individually and singly, are all more or less equivocal, and may arise from other conditions of the part, being common to various injuries. It is rather by their simultaneous occurrence that we consider them as pathognomonic of the existence of a broken bone. Amongst the more equivocal signs may be mentioned the occurrence of pain in the limb, which may be owing either to the laceration of the soft parts by the broken fragments, or to the general injury inflicted upon it. So also the existence of increased or diminished swelling is observed in different cases of fracture; the augmented swelling being owing either to the extravasation of blood into the limb, which often takes place to a very considerable extent, even without the wound of any principal vessel; or, to the approximation of the attachments of the muscles, by the shortening of the part. Diminished swell- ing, or flattening, occurs in some cases, in consequence of the weight of the limb drawing the part down, and thus lessening natural rotundity. The more special and peculiar signs of fracture are three in number: 1st, A change in the shape of the limb ; 2d, Mobility in its continuity; and 3d, The existence of grating between the broken ends of bone. 1st. The change in the shape of the limb, due to the displacement of portions of the broken bone, is perhaps the most important sign of fracture; it manifests itself by a want of correspondence between the osseous points on opposite sides of the body, by an increase or diminution of the natural curves of the limb, by angularity, shortening, or swelling. In investigating the existence and extent of displacement in a case of frac- ture, the surgeon should always strip his patient, compare the points of bone on the opposite sides of the body, and their relative situation to some fixed and easily distinguishable neighboring prominence on the trunk or injured part of the limb. From this the measurements may be taken, by grasping the injured part and the corresponding portion of the healthy limb in either hand, and running the fingers lightly over the depressions and elevations, marking any difference that exists; or, if greater accuracy be required, measuring by means of a tape. In some cases the measurement must not be made between the trunk and the limb injured, or even from one extremity of the limb to the other, as shortening of the whole member might depend on other causes than fracture, such as wasting, diseases of joints, or dislocation, but the measurement must be taken between different points of the bone actually injured. The displacement of a broken bone may be the direct result of the violence which occasions the fracture, the fragments being driven out of their position, SIGNS OF FRACTURES. 189 as when a portion of the skull is beaten in; or it may result from the weight of the limb dragging downwards the lower fragment, as in a case of fractured acromion. In some cases, it is either occasioned, or greatly increased, by the direction of the fracture. Thus, in several cases of broken tibia which have been under my care, the line of fracture being oblique from above downwards, and from before backwards, I found the upper end of the lower fragment pro- ject considerably forwards, sliding, as it were, along an inclined plane in the upper one, and in one of these cases that I had an opportunity of dissecting after amputation, the direction of the fracture, rather, than muscular action, appeared to be the cause of displacement. In transverse fractures there is always but slight displacement. Muscular contraction is, however, without doubt, the most frequent cause of displacement; hence, it has been found that in paralyzed limbs that are fractured, there is but little deformity. The contraction of the muscles of the part approximating their points of attachment, owing to the support or resist- ance offered by the bone being removed, draws the most movable fragment out of its normal position. The other causes that have just been mentioned, tend greatly to favor this kind of displacement; but in some cases, as in fractured patella, the displacement is entirely muscular, and in all fractures of the long bones it is chiefly due to muscular contraction. The direction of the displacement is principally influenced by the direction of the fracture, the position of the limb, and muscular action; it may be angu- lar, transverse, longitudinal, and rotatory. In the angular displacement there is an increase of the natural curvature of the limb; the concavity of the angle being on the side of the most powerful muscles; thus, for example, in fracture of the thigh, the angle projects on the anterior and outer side of the limb, because the strongest muscles being situated behind and to the inner side, tend, by their contraction, to approximate the fragments on that aspect. This displacement principally occurs in oblique and comminuted fractures. The transverse or lateral displacement occurs when a bone is broken directly across, the fragments often hitching one against another, and so being, as it were, entangled together. In this case there is often but very little deformity. In the longitudinal displacement there may be either shortening or elonga- tion of the limb. When there is shortening, as most commonly happens in oblique fractures, it is dependent on muscular contraction, the broken ends of bone being drawn together so as to overlap one another, or "riding." In other cases, the shortening may be owing to the impaction of one fragment in the other. In some cases there is preternatural separation of the fragments, the weight of the limb tending to drag the lower one downwards, or muscular con- traction drawing the upper one away from it. The rotatory displacement is owing to the contraction of particular sets of muscles twisting the lower fragment on its axis, as well as producing shortening of the limb. Thus, the external rotators in fractures of the neck of the thigh bone, and the supinators in some fractures of the radius, have a tendency to twist or rotate the lower fragment in an outward direction. 2d. The occurrence of preternatural mobility in the continuity of a bone cannot exist without fracture, and separation of the fragments from one another; hence, its presence may always be looked upon as an unequivocal sign of the bone being broken. It occasionally happens, however, that fracture may take place, and, owing to the impaction or wedging together of the fragments, mobility not be perceived; hence, its absence cannot in all cases be construed into a proof of the non-existence of fracture. 3d. Another sign of much value in practice is the occurrence of crepitus, or rather of the grating together of the rough surfaces of the broken bone, which 190 FRACTURES. can be felt as well as heard on moving the limb. This grating can only occur when the fragments are movable and in contact, and is especially perceptible when the rough ends of the broken bone are directly rubbed against one an- other, and not the smooth periosteal surfaces merely opposed, or overlapping. It is not, however, an invariable accompaniment of fracture, being absent in some cases, in which the fracture is firmly impacted, or when the fragments are widely separated. It must not be confounded with crepitation that occurs in the limbs from other causes, as from emphysema, or the effusion of serous fluid into the sheaths of the tendons, which gives rise to a peculiar crackling sensa- tion, very different from the rough grating of a fracture. It will thus be seen that each of these symptoms, taken individually, is more or less equivocal, and that it usually requires a combination of at least two of them to determine whether fracture exists. In ascertaining the existence of a fracture, the surgeon should make the necessary manipulations with the utmost gentleness, but yet effectually, so that no uncertainty may be allowed to remain as to the seat and nature of the injury, more especially when it occurs in the vicinity of a joint. The increased mobility may be ascertained by fixing the upper fragment, and rotating the lower portion of the limb; the grating, by drawing down the lower fragment, so as to get the rough surfaces in apposition and then grasping the limb at the seat of fracture with one hand, rotating it gently with the other. The displacement must be ascertained by measuring'the limb carefully in the way that has been directed, and by comparing the injured with the sound side. _ A fractured bone is ultimately united by being soldered together by the depo- sition of new bone around, within, and lastly between, the broken fragments. In exceptional cases, as in fractures occurring within the capsule of a joint, and in those of the patella and the olecranon, union is effected by fibrous or fila- mentous tissue. In some instances that will hereafter be considered, owin^ to peculiar, local, or constitutional circumstances, new bone is not formed, but^the uniting medium is of a fibrous character. The new bone that constitutes the bond of union is termed callus. In many cases, a larger quantity of this is temporarily deposited than is permanently left. This temporary formation of bone goes by the name of the " provisional callus." It is formed partly external to the fracture, incasing the broken ends, and partly in the medullary canal, so as to include the fragments between layers of new bone and thus maintain them in contact. That which is permanently left, and which intervenes between the broken ends, is called the " definitive callus." The production of callus has been studied with much care by Haller Duha- mel, Bordenave and Hunter, by Dupuytren, Breschet and Villerme, and more recent y by Stanley and Paget. From the observations of these pathologists, it would appear, that the union of a broken bone takes place through the medium oi_ plastic matter deposited by a process of adhesive inflammation set up in the injured bone itself, its periosteum, and the neighboring soft parts; the lymph thus formed gradually undergoing development into osseous tissue. The whole process, indeed, is strictly analogous to that which takes place in the ordinary healing of a wound by adhesion, and the development of the cicatrical tissue The broken fragments are at first movable, and surrounded by a considerable extravasation of blood. In the course of ten or fourteen days this has ordinarily undergone absorption to a considerable extent; the periosteum and the medul- hrirf ^V^ v6 V1Cimtj °f thG fracturMhe tissues around it and the broken bone itself become very vascular, and pour out a quantity of lymph thtt Zft arT\the fragmen^^ll as within the medullary ca/al, lo 111 Jil T f &T1 ensheathed by a reddish gelatinous mass of a fusiform morPe cinS d \T°S1^ ' "*' °? "^ This Sradually beco™s more and more consolidated, and in proportion as it becomes firmer, the mobility of the fragments lessens, and the ends of the bone becoming smooth by the* pa ti UNION OF FRACTURES. — CALLUS. 191 deposit being adherent to, and interposed between them, grating is less distinct. From the third to the fourth week the lymph has assumed a sufficient degree of firmness to keep the fragments in apposition, though the bone still yields readily at the seat of fracture. This lymph, which is poured out not only by the periosteum and bone, but by all the soft parts in the neighborhood of the fracture, gradually undergoes ossification, the bony matter being first deposited in a granular manner, but in sufficient quantity by the sixth or eighth week to unite, the fracture pretty firmly. The callus, which is at first soft and spongy, and differs from old bone in its microscopic as well as ordinary physical charac- ters, gradually assimilates to old bone, both in hardness and in structure; osseous corpuscles and vascular laminated canals forming in it; and it becomes smooth on the surface, being invested by a dense cellulo-fibrous periosteum, until, by the end of six or eight months, ossification is perfect. The last process in the consolidation of the fracture is the formation of new bone between the broken ends. This does not take place definitely until a considerable period after the ensheathing callus has been formed. This bone is deposited in the plastic matter effused between the fragments, which undergoes ossification in the same way as the external callus does. By the time that this intermediate or defini- tive callus is fully formed, that portion of the ensheathing or provisional callus which is not required for the preservation of the permanent integrity of the bone, has been gradually removed, or has moulded itself closely to the shape and condition in which it will ultimately remain, the medullary canal having again become free, and the ends of the fracture rounded off. In some cases the medullary cavity is not restored to its former condition for a considerable time, continuing to be partially occluded by a thin septum of callus. According to Paget, the plastic matter that is effused around and between the bones undergoes ossification in various ways. Those fractures that ossify quickly do so most commonly through nucleated blastema, a fine closely-granular ossific deposit taking place in the blastema, and becoming converted into the laminae of the cancellous tissue, the nuclei becoming probably converted into bone corpuscles. In other cases again, the nucleated cells of granulations and plastic effusions ossify by being transformed into bone. Then, again, the new bone may be formed by the plastic exudation passing, first of all, through the stages of fibrous tissue, of cartilage of the purest foetal form, or through fibro- cartilage. In those fractures that are transverse, and that remain in steady apposition during ossification, and more especially if they are but thinly covered by soft parts, the union appears to take place directly and immediately between the opposed osseous surfaces; there being no appearance of those accessory deposits of bone that usually go by the name of " provisional callus." If, however, the fracture occurs in a bone that is thickly invested by soft parts, masses of new bone will be thrown out around the fragments, evidently the result of deposition from the surrounding inflamed tissues, rather than from the injured periosteum or bone. The influence of neighboring soft parts in determining the deposits of new bone is well marked in the tibia. In a fracture of this bone we find, that at the anterior and inner part, which is thinly covered, union takes place directly between the broken ends; but at the posterior and outer side, where there is a thick envelopment of tissue, a large mass of provisional callus will often be found filling up even the interosseous space. That neighboring parts participate in the inflammation set up around the fracture, and throw out callus, is evident by what takes place occasionally when one of the bones of the fore- arm or leg is broken. Periostitis is then set up in the unbroken bone, opposite the seat of fracture, and osseous matter sometimes deposited by it. We have specimens illustrating this point in the University College Museum. If the fracture be not well reduced, the ends not being in proper apposition, or if it is comminuted, it will commonly be found that masses of* new bone are 192 FRACTURES. deposited as buttresses or supports; or, enveloping the splinters, consolidate them in this way with the rest of the shaft. So, also, if the fractured bones are not kept sufficiently quiet during treatment, the neighboring parts become irritated, and provisional callus is formed. Hence, as Paget has remarked, we commonly find this deposit in fractures of the ribs, which are kept in constant motion by the respiratory actions. In impacted fractures there is, from the perfect apposition of the surfaces, but little callus formed. From all this, I think it clear that in simple fractures the provisional callus is deposited principally by the surrounding soft tissues, and also, to a certain extent, by the periosteum and medullary canal, its quantity being dependent on the amount of irritation set up in these textures. The definitive callus, on the other hand, is directly and immediately formed by the vessels of the frac- tured bone itself, and the comparative want of vascular supply to this tissue may account for the slowness of its formation. In compound fractures, union takes place by the ends of the bone, which lie bathed in the pus of the wound, granulating and throwing out plastic matter, which becomes directly converted into bone. There is in many cases but little provisional callus; but in most instances a large quantity of accessory osseous deposit takes place, more particularly if the displacement be considerable. The union of these fractures precisely resembles that of a wound in the soft structures — by granulation — the process occupying a much longer time than that which is necessary for the union of simple fractures, consolidation not being effected for three or four months. Rokitansky is of opinion that superficial exfoliation of that layer of bone which is bathed by the pus, takes place, and that it is after this has separated that the granulations spring up, in which the new bone is deposited. I think it admits of very considerable doubt whether this process of necrosis goes on in all cases of compound fracture. Union of fractures, like all other vital actions, takes place more readily and much more quickly in the early periods of life than at a more advanced age, and is always more speedily accomplished in the upper than in the lower extremities. TREATMENT OF SIMPLE FRACTURES. In conducting the treatment of a fracture, the object of the surgeon should be not only to obtain a sound and strong limb, but one that presents as little deformity and trace of former injury as possible. In order to accomplish this, the broken ends of the bone must be brought into as perfect apposition as possible, the recurrence of displacement must be prevented, and the local and constitutional condition of the patient properly attended to. When the surgeon is called to a person who has met with a fracture, if it be a severe one of the upper extremity, or of any kind of the lower limbs, he must see that the bed, on which the patient may have to remain for some weeks, is properly prepared, by being made hard, flat, and firm, and, if possible, covered with a horse-hair mattress. The surgeon must then superintend the removal of the patient's clothes, having them ripped up the seams, so that they may be taken off with as little disturbance to the injured part as possible. He next proceeds to the examination of the broken limb, using every possible gentleness consistent with acquiring a proper knowledge of the fracture. After satisfying himself upon this point, the limb should be laid upon a soft pillow, until any necessary apparatus that may be required has been prepared. When all has been got ready, the reduction of the fracture, or the bringing the fragments into proper apposition, must be proceeded with. This should, if possible, always be done at once, not only lest any displacement that exists may continue permanently,—the muscles, after a few days, becoming shortened, rigid, and unyielding, not allowing reduction to be effected without the employ- ment of much force, — but also with the view of preventing irritation and TREATMENT OF SIMPLE FRACTURES. 193 mischief to the limb, by the projection of the sharp and jagged ends of bone into the soft structures. By early reduction we may sometimes prevent a sharp fragment perforating the skin, thus rendering a simple fracture compound, or lacerating muscles and nerves, inducing perhaps traumatic delirium, and certainly undue local inflammatory and spasmodic action. The great cause of displacement in fractures has already been stated to be muscular contraction; hence, in effecting reduction of a fracture and in remov- ing the displacement, our principal obstacle is the action of the muscles of the part. This must, and always may be, counteracted, by properly relaxing them by position; so soon as this is done, the bony fragments will naturally fall into place; but no amount of extension and of counter-extension can get these into position, and much less retain them there, unless all muscular influence be removed. In ordinary fractures no force is necessary for this, or should ever be employed in accomplishing it; but attention to the attachment of the muscles of the limb and proper relaxation of them is all that is required. In impacted fractures it is occasionally necessary to use force in order to disentangle the fragments, but this is the only form of fracture in which its employment is justifiable. In effecting the reduction, not only must the length of the limb be restored, but its natural curves must not be obliterated by making it too straight. After the reduction has been accomplished, means must be taken to prevent the return of the displacement; for if the parts be left to themselves, muscular action, or the involuntary movement of the patient, would be certain to bring about a return of the faulty position. In many cases it is exceedingly difficult to preserve the fracture undisplaced for the first few days after its occurrence, in consequence of spasmodic movement of muscles of the limb, or of restlessness on the part of the patient. About this, however, the surgeon need not be anxious, as no union takes place for the first week or ten days; at the expiration of that time, the muscles will have probably lost their irritability, and the patient have got accustomed to his position, so that with a little patience, or by varying the apparatus and the position of the limb, good apposition may be maintained. The return of displacement is prevented, and the proper shape and length of the limb are maintained, by means of bandages, splints, and special apparatus of various kinds. In applying these, care should be taken not to exert any undue pressure on the limb. Pads and compresses of all kinds should, if pos- sible, be avoided; they do no good that cannot be effected by proper position, and often occasion serious mischief by inducing sloughing of the integuments, over which they are applied. Screw apparatus has been invented with the view of forcing fragments into proper position, but nothing can be more unsurgical and unscientific than such barbarous contrivances as these.' In cases in which there is much tendency to a return of the displacement, it has been recommended to divide the tendons of some of the stronger muscles inserted into the lower fragment. This, however, can very rarely be necessary, and in those cases in which I have done it, or seen it done, no material benefit has resulted. The bandages used for fractures should be the ordinary grey calico rollers, about three fingers' breadth in width, and of sufficient length. In applying them, especial care must be taken that the turns press evenly upon every part, and that the bandage be not applied too tightly in the first instance. No bandage should ever be applied under the splints. In this situation they are not only useless, but highly dangerous, by inducing risk of strangulation. The limb should also be examined from time to time, and if the patient complain of any pain or numbness, or if the extreme part look blue and feel cold, the bandage must be immediately removed; for though it have not been applied tightly, swelling of the limb may come on from various causes, to such an extent as to produce strangulation, and consequent gangrene of it, as I have 13 194 FRACTURES. seen happen in at least three instances, the limb requiring amputation in both cases (Fig. 83). It is remarkable that the whole of a limb will fall into a state of gangrene under these circumstances, with but little pain, and often with very slight constitutional disturbance, the parts having their sensibility deadened by the gradual congestion and infiltration of the tissues. When such an unfortunate accident happens, immediate amputation must be had recourse to. Before applying the bandage in a case of fracture, and as often as they are taken off, it is a good plan to sponge the limb with warm soap and water, which prevents the itching that otherwise occurs, and is sometimes very troublesome. The splints that are used in cases of fracture are of various kinds. Tin, wood, leather, and gutta-percha, are the materials usually employed. For some kinds of fracture, special and often very complicated apparatus is very generally used; but the surgeon should never confine himself to one material, or one exclusive mode of treating these injuries, as in different cases special advantages may be obtained from different kinds of splints. Wood and tin are principally employed in the lower extremity, where great strength is required to counteract the weight of the limb and the action of its muscles, and care must be taken to pad very thoroughly splints made of these materials. Leather, gutta-percha, and pasteboard are more commonly useful in fractures of the upper extremity, though they may not unfrequently be employed with advantage in the lower limbs. In applying them, a pattern should first be cut out in brown paper, of the proper size and shape; the material must then be softened by being well soaked in hot water, and moulded on to the part whilst soft; so soon as it has taken the proper shape, it should, if leather or gutta-percha is used, be hardened by being plunged into cold vinegar and water; the pasteboard must be allowed to dry of itself. Its edges may then be pared and rounded, and its interior lined with wash-leather or lint. These splints have the advantage of great durability, cleanliness, and lightness. The material of which the splint is composed is of less consequence than its mode of application. There are two points that require special attention in this respect:—1st, That the splint is sufficiently broad to extend to the exterior of the limb, and not to press into it; and, 2d, that it embrace securely and fix steadily the two joints connected with the fractured bone; if the thigh, the hip and knee; if the leg, the knee and ankle : from want of attention to this, much deformity often results. Special apparatus should be employed as little as possible in the treatment of fractures. It is scarcely ever necessary in simple fracture, and is far more cumbersome and costly than the means above indicated, which are all that can be required. I have no hesitation in saying, that a surgeon of ordinary ingenuity and mechanical skill may be fully prepared to treat successfully every fracture to which he can be called, by having at hand a smooth deal plank half an inch in thickness, a sheet of gutta-percha, undressed sole-leather, or pasteboard, to cut into splints as required. To these simple means the starch bandage is an invaluable addition. Although various plans for stiffening and fixing the bandages in cases of fracture, by smearing them with white of eggs, with gum, plaster of Paris, etc. have been employed at various times, it is only of late years that the full value of the starch bandage has been recognized by surgeons, chiefly through the practice and writings of M. Seutin of Brussels. The advantages of the starch bandage in the treatment of fractures, as well as in many other injuries and diseases, consists in its taking the shape of the limb accurately and readily, and maintaining it by its solidity; in being light, inexpensive, and easily applied, with materials that are always at hand. From its lightness, it possesses the very great and peculiar advantage in fractures of the lower extremity, of allowing the patient to remain up and to move STARCH BANDAGE IN FRACTURES. 195 about upon crutches, during nearly the whole of the treatment, and thus, by rendering confinement to bed unnecessary, preventing the tendency to those injurious consequences that often result from these injuries; and, by enabling the patient to keep up his health and strength by open air exercise, facilitating the consolidation of the fracture. In addition to this, the patient will often be able to carry on his business during treatment. By employing the starch bandage in the way that will be immediately pointed out, I scarcely ever find it necessary to keep patients in bed with simple fractures of the thigh for more than six or seven, or of the leg for more than three or four days, thus saving much of the tediousness and danger of the treatment. The following is the mode of applying this apparatus that is adopted at the University College Hospital, and which will be found to answer well. The whole limb is enveloped in a layer of cotton wadding, which is thickly laid along and over the osseous prominences; over this should be laid splints of thick and coarse pasteboard, properly shaped to fit the limb, extending beyond and fixing securely the two joints above and below the fracture, and well soaked in thin starch. The pasteboard should be soft, not milled, and be double, and torn down, not cut, as in this way the edges are not left sharp. If much strength is not required, as in children, or in some fractures of the upper extremity, a few slips of brown paper, well starched, may be substituted for the pasteboard. A bandage saturated with thick starch must now be firmly applied; and, lastly, this is to be covered by another dry roller, the inner sides of the turns of which may be starched as it is laid on. During the application of this apparatus, extension must be kept up by an assistant, so as to keep the fracture in position; and, until the starch has thoroughly dried, which usually takes from thirty to fifty hours, a temporary wooden splint may be applied to the limb, so as to keep it to its proper length and shape. The drying of the starch may, if necessary, be hastened by the ap- plication of hot sand-bags to the apparatus. After the bandages have become quite dry, the temporary splints must be removed, and the patient may then be allowed to move about on crutches, taking care, of course, to keep the injured limb well slung up, and not to bear upon it, or to jar it against the ground (fig. 79). In the course of about three or four days after its applica- tion, the apparatus will usually be found to have loosened somewhat, the limb ap- pearing to shrink within it. Under these circumstances it becomes necessary to cut it up with a pair of Seutin's pliers, such as are represented in the annexed wood-cut (fig. 80). This section must be made along the more muscular part of the limb, so that the skin covering the bones be not injured, as represented in fig. 81, and after paring the edges of the splint, it must be reapplied by means of tapes or a roller. It will al- ways be found advantageous to adopt the practice of M. Burggraeve, of Ghent, and to envelop the whole limb in a thick layer of cotton wadding before applying the starched bandage; this, being elastic, accommodates itself to the diminution in the size of the limb, and thus keeps up more equable pressure. Indeed, of 196 FRACTURES. late I have invariably adopted this practice, and found much advantage from it, dispensing with any dry roller next the skin which there is always difficulty in applying, and from which Fig. 80. there is danger of constriction or of abrasion. In trimming the edges of the splint, it should not be removed from the limb, and, after this has been done, the apparatus must be fixed together again with tapes or a roller. If the frac- ture be compound, a trap may be cut in the apparatus opposite the seat of injury, through which the wound may be dressed (fig. 82). Fig. 81. Fig. 82. Although fully recognising the great advantages to be obtained by treating fractures on this plan, and employing the starch bandage in almost every case that came under my care, I did not think that it was a safe practice to have recourse to it during the early stages of fracture, until, indeed, the swelling of the limb had begun to subside. I therefore never applied it until the sixth, or eighth, or tenth day, keeping the limb properly reduced upon a splint, very lightly bandaged, wet with cold evaporating lotions until this time, fearing that if the bandage was applied at too early a period, the inflammatory turgescence of the limb might give rise to a slow strangulation of it under the bandages. During the last few years, however, I have fol- lowed Seutin's plan in some hundreds of fractures of all kinds, putting the limb up in the starch appa- ratus immediately on the occurrence of the injury, and have found the practice an extremely successful one, even in fractures of the thigh; so much so, that at the hospital I now rarely use any other plan of treatment; and, indeed, the more experience of it, the more satisfied am I with the results obtainable by it. I find that the moderate pressure of the ban- dages, aided probably by the great evaporation that goes on during the drying of so extensive and thick a mass of wet starch, and which produces a distinct sensation of cold in the limb, takes down the extravasation most effectually, ACCIDENTS AND COMPLICATIONS OF FRACTURE. 197 and enables the patient usually to leave his bed about the third day after the injury, when the fracture is in the leg or ankle, and about the sixth when it is the thigh that is broken; so that very commonly we now treat all patients with simple fractures of the leg, and many of those of the thigh, especially in children, as out-patients.1 By no other means of treatment have I seen such satisfactory results in cases of fractured thigh, as by the starched apparatus, patients having fre- quently been cured without any shortening whatever, and with the preservation of the natural curve of the bone. In compound fractures, also, of the legs and even of the thigh, I have obtained most satisfactory results by this means. In compound fracture of the leg, I have seen the patient walking about on crutches as early as the tenth or fourteenth day, the limb being securely put up in starch; and have more frequently succeeded in getting union of the wound, and consequently in con- verting the compound into a simple fracture, by putting up the limb in this apparatus, than in any other. The plaster of Paris bandage may sometimes be advantageously used as a substitute for the starch apparatus. It may be applied in the following way: A roller of coarse soft muslin must have dry plaster of Paris thoroughly rubbed into its meshes, some cold water is then to be poured upon either end of it, so as to moisten it through. A dry roller having been previously applied to the limb, the wetted plaster bandage must be smoothly rolled up it, the surgeon taking care that no reverses are made. In order to avoid these, it may be applied in a spiral or figure of 8 manner over the more unequal parts. Slips of the plaster bandage should also be laid on where additional strength is required, and the whole well wetted from time to time during the application. It hardens in the course of a few minutes, and, as it dries, forms a solid, hard, and light casing to the limb, affording excellent support to the fracture. The plaster bandage possesses the advantage over the starch apparatus of being lighter, and especially of drying and hardening quickly, qualities which render it invaluable in cases in which it is necessary to carry patients any distance soon after the setting of the fracture. Various Accidents are liable to occur during the treatment of a fracture; some of these are of a general, others of a special, character. Amongst the more general accidents, tetanus, traumatic delirium, and erysipelas, may be mentioned as the most common. Amongst the more special, the occurrence of spasm of the muscles of the limb, abscess, oedema, gangrene, and a tendency to pulmonary and cerebral congestion, are those that have most to be guarded against. In order to prevent the occurrence of these conditions, the general health must be carefully attended to, the bowels being kept open, the room well venti- lated, nourishing diet allowed, and long confinement to bed avoided by the use of the starch bandage. The treatment of the more general accidents presents nothing that need de- tain us here; but those that are more special and peculiar to fractures, require consideration. Spasm of the muscles of the limb, owing to the irritation produced by the fragments, is best remedied by reduction, and the maintenance of the fracture in proper position, by moderate pressure with a bandage. If the spasm be dependent upon nervous causes, full doses of opium will not unfrequently afford relief. In some cases, it is of a permanent character, producing con- siderable displacement of the fragments. Under these circumstances, the division of the tendons has been recommended, but this practice appears to be 1 For details of this mode of treatment, I would refer the reader to Mr. Gamgee's very practical work on the starched apparatus. 198 FRACTURES. an unnecessarily severe one, and may certainly most commonly be avoided by attention to the other plans of treatment which have been suggested. Considerable extravasation of blood is frequently met with in cases of simple fracture, causing great swelling and tension of the limb. By the continuous application of cold evaporating lotions, these collections are usually readily absorbed, and the surgeon should never be tempted by any feeling of fluid or of fluctuation to open them, as he would thereby infallibly convert the simple into a compound fracture, and give rise to extensive ill-conditioned suppuration. In some of these cases of extensive extravasation, the limb appears to relieve itself of the serous portion of the blood effused, by the formation of large bullae or blebs, which burst or subside, without any material inconvenience. This extravasation very rarely, indeed, runs into abscess; if it do, it must of course be opened, and treated upon ordinary principles. It may lead to gangrene if deeply effused, by the constriction and compression it exercises on the muscles of the limb. (Edema and gangrene of the limb, may occur as the result of tight bandaging, or else by the swelling of the limb consequent upon extravasation of blood, or inflammatory infiltration causing strangulation of it within a bandage that has been but lightly applied. The occurrence of such accidents should make the surgeon cautious in applying a bandage with any degree of tightness in the early stages of fracture, or, in those cases in which there is already much swelling; and the apparatus should at once be removed whenever the patient complain, even of slight uneasiness; or, indeed, if any appearance of con- Fig. 83. gestion, such as blueness, coldness, or vesications of the fingers and toes show themselves. If left on beyond this, gangrene will probably set in, slow strangulation going on under the bandages without much, if any, pain. An excellent plan of judging of the activity of the circulation in a fractured limb after it has been put up, is to leave the ends of the fingers or toes uncovered by the bandage, when by pressing upon one of the nails, the freedom of the circulation may be ascertained, by noticing the rapidity with which the blood returns under it. In fractures occurring in old people, there is a great tendency to pulmonary and cerebral congestion, partly from determination of the blood, and partly as a consequence of the long confinement required; these fractures commonly proving fatal in this way. The use of the starch bandage, by enabling the patient to get about, is the most effectual prevention to these accidents. Fractures may be complicated with various important local conditions. Thus the extravasation of blood into the limb may arise from a wound of some large vessel, and this may go on to so great an extent as to occasion strangulation of the tissues; if not checked by position and cold applications, it may give rise to gangrene, and lead to amputation. In other cases, again, the soft parts in the vicinity of the fracture may be contused to such a degree that they rapidly run into slough, thus rendering it compound; or a wound may exist, not com- AMPUTATION IN COMPOUND FRACTURES. 199 municating with the broken bone, but requiring much modification of treatment, and special adaptation of apparatus. The most serious complication of simple fractures, consists in their implicating a joint. The fracture may extend into a neighboring articulation, and thus give rise to considerable inflammatory action, though in some cases no incon- venience results, even though the capsule be perforated by a sharp fragment; but in strumous subjects it may lead to ultimate disorganization of the articula- tion, requiring excision, which I have several times had occasion to perform in these cases. The complication of dislocation with fracture often occasions great difficulty to the surgeon, as it becomes necessary to reduce the dislocated joint before the fracture is consolidated. In several cases of this description which have fallen under my care, I have succeeded in reducing the dislocation at once, by putting up the limb very tightly in wooden splints, so as to give a degree of solidity to it, and to permit the lever-like movement of the shaft of the bone being employed; and then, putting the patient under chloroform, have replaced the bone without much difficulty. Should the surgeon have neglected to reduce the dislocation in the first instance, it will be necessary for him to wait until the fracture has become firmly united, and then, putting up the limb in splints or in starch, to try to effect the reduction, which, however, will then be attended by very great difficulty. In cases of simple fracture occurring in the neighborhood of, or implicating large joints, passive motion is very commonly recommended at the end of from four or six weeks; I think, however, with Mr. Vincent, that this is often apt to do more harm than good, and is seldom required, the natural action of the muscles of the part being fully sufficient to restore the movements of the arti- culation, which may be assisted by friction and douches. COMPOUND FRACTURES. A compound fracture is that form of injury in which there is an open wound leading down to the broken bone, at the seat of fracture. These injuries are not only far more tedious in their cure than simple fractures, but infinitely more dangerous. The tediousness depends upon the communication of the fracture with the external air, causing it to unite by a slow process of granulation, instead of by the more speedy adhesive action that occurs in the simple form of injury. The danger is likewise partly due to the same cause, the process of granulation and suppuration being often attended by such profuse discharge of pus, from abscesses or long-continued exfoliation of bone; or by the superven- tion of secondary disease, such as hectic, phlebitis, pneumonia, or erysipelas, as to lead to the eventual loss of limb or life. Besides these dangers, which may be looked upon as of a remote kind, the violence that occasions a compound fracture often shatters the limb to such an extent, as to lead to the immediate supervention of traumatic gangrene, to the loss of life by hemorrhage, or to the certain and speedy disorganization of the limb, as the consequence of the reactionary inflammation. As there are, therefore, not only prospective dangers of great magnitude to be encountered in these injuries, but also immediate risk of a very serious cha- racter to be met, the first question that always presents itself in a case of com- pound fracture is, whether the limb should be removed, or an attempt be made to save it. It is of great importance to settle this point at once, for, if ampu- tation be determined upon, it should be had recourse to with as little delay as possible, there being no period in the progress of the case so favorable for the performance of this operation as the first four-and-twenty hours. Should an injudicious attempt have been made at saving the limb, the surgeon must wait until suppurative action has been set up before he can remove it; and then, he 200 FRACTURES. will very commonly find that the occurrence of some of the diffuse inflammatory affections of an erysipeloid character will render any operation impracticable; or the supervention of traumatic gangrene may compel him to have recourse to amputation under the most unfavorable circumstances. At a late period in the progress of the case, amputation may be required, in order to rid the patient of a necrosed and suppurating limb that is exhausting him by the induction of hectic. Though advocating the early performance of amputation in those cases which imperatively require it, I am aware that these operations are very commonly fatal, especially when practised near the trunk; but yet, this cannot with justice be urged as an argument against their performance, as immediate amputation should never be had recourse to except in the most severe cases, in which it is evident that the patient's life must in all probability be sacrificed, by the un- successful attempt to save the limb. In determining the cases in which imme- diate amputation should be performed, no very definite rules can be laid down, and much must at last be left to the individual judgment and experience of the surgeon. One will attempt to save a limb which another condemns. But, in coming to a conclusion upon this important question, he must bear in mind, that though it is imperative to do everything in his power to save a limb, yet that the preservation of the patient's life is the main point, and that that course is the proper one which offers the greatest prospect of effecting this. In coming to a conclusion on a question of such vital moment as this, he must be guided, not only by the nature and extent of the fracture, but by the age, con- stitution, and habits of the patient (p. 119). Those fractures must be looked upon as most unfavorable, in which the wound is the consequence of the violence that breaks the bone, and in which there is much laceration of, and extravasation into, the soft parts; more parti- cularly if the integuments are stripped off, portions of the muscular bellies pro- truding, and the planes of cellular tissue between the great muscles of the limb torn up and infiltrated with blood. Injuries of this description occurring in the lower extremity always require amputation. Now the danger to the patient increases almost in the exact ratio of the proximity of the injury to the trunk. Thus amputation of the thigh for bad compound fractures of the leg, though a very serious operation, is sufficiently successful; but when the femur itself is badly fractured, and amputation of the thigh high up is required, recovery can indeed but seldom be expected. In the arm, they are not so serious, and admit of the member being saved, unless the bones be greatly comminuted. The complication of a compound fracture with the wound of a large joint, more_ especially if there be crushing or splintering of the bones which enter into its formation, when occurring in the lower extremity, is always a case for amputation. When the elbow and shoulder joints are extensively crushed and injured, amputation of the arm must be practised; but if the injury be local- ized, and the soft parts be in a favorable state, resection of the articulation may be successfully practised. These operations are usually somewhat irregular proceedings, being conducted according to the extent of the wound, and con- sisting rather in picking out the shattered fragments of bone, than in metho- dical excision. When one of the larger arteries of the limb has been wounded by the vio- lence that occasions the fracture, or has been lacerated by the broken bone, there may be copious arterial hemorrhage externally, as well as extravasation into the general cellular tissue of the limb. These cases most commonly re- quire immediate amputation. But whilst the patient is being examined, and preparations made for the operation, care must be taken that a dangerous quan- tity of blood be not lost. This must be prevented by the elevated position and the application of a tourniquet. For want of this simple precaution I have TREATMENT OF COMPOUND FRACTURES. 201 seen very large and even fatal quantities of blood gradually lost, by being allowed slowly to trickle from the wound. In these cases it has been proposed, by some surgeons of great eminence, to enlarge the wound in the limb, or to make an incision down to the fracture, and to attempt to tie the artery where it has been injured. In most cases, however, this is scarcely practicable, as the surgeon would have to grope in the midst of bleeding and infiltrated tissues, and would experience the greatest possible difficulty in finding the wounded vessel, after a search which would materially tend to increase the disorganization of a limb. Even after the re- moval of a limb in this condition it is by no means easy to find the artery that has poured out blood; and how much more difficult must it not be to search for it successfully during life ? The ligature of the artery at a higher point of the limb does not hold out much prospect of success, for the same reasons that render its employment in- admissible in ordinary wounds of arteries. If, then, proper means directed to the wound, such as position, pressure, or perhaps the attempt at ligature if the artery be easily reached, are not successful, no course is left to the surgeon but to amputate the limb without delay. This is more especially the case if it be the lower extremity that is injured. In the arm there is a better prospect of our being able to arrest the bleeding without having recourse to this extreme measure. If, however, the compound fracture be unattended by any of the complica- tions that have just been mentioned, occurring in a young and otherwise healthy subject, we must, of course, attempt to save the limb, and shall generally succeed in doing so. Treatment. — In the management of a compound fracture, special apparatus, such as M'Intyre's, Liston's, or the bracket-splints, double inclined planes, swing boxes, and fracture beds, are often necessary, in order to obtain access to the wound, so as to dress it properly, and to place the limb in the best position for union. In many cases the starch bandage may very advantageously be used, but it requires caution, as swelling and consequent strangulation of the limb may take place under it. The reduction of compound fractures must be accomplished with the same attention to gentleness as in that of simple ones. In the majority of cases, no great difficulty is experienced in effecting this, and after it has been done, the limb should be placed on a well-padded splint, properly protected in the neigh- borhood of the wound with oiled silk, so as to prevent soiling of the pads by blood and discharge. In some cases, however, considerable difficulty arises in the reduction, from the protrusion of one of the broken fragments which has been driven through the skin, either by careless handling of the limb in carry- ing the patient, or else by the muscular contractions dragging the lower frag- ment forcibly upwards, and thus causing perforation of the integument. The protruded bone must, if possible, be gently replaced, by relaxing the muscles of the limb, and thus bringing the soft parts over it. In some cases, however, it is so tightly embraced by the skin, which appears to be doubled in underneath it, that enlargement of the wound becomes necessary before it can be replaced. In other cases again it will be found that reduction cannot be effected or main- tained, unless the sharp and projecting point of bone be sawn off. This must be done carefully by protecting the neighboring soft parts with a split card. The limb, as I have found in several cases in which it has been necessary to have recourse to this procedure, is not ultimately weakened by it. After the reduction, the great object is, if possible, to convert the compound into a simple fracture by the closure of the external wound. If this can be accomplished, the tediousness and danger of the case are greatly lessened, the whole process of suppuration, with all its attendant evils, being saved to the patient. If the wound be small, clean cut, and occasioned by the protrusion of 202 FRACTURES. the fragment rather than by the direct violence which occasions the fracture, we may hope to succeed in our object by following Sir A. Cooper's recommen- dation of applying to it a piece of lint soaked in its blood; or, what is better, saturated with collodion, and thus obtaining union by adhesion. If the wound be large, if a joint have been opened, if it have been inflicted by the same violence that breaks the bone, or if there be much bruising of the edges and surrounding tissues, with extravasation into the limb, this direct union cannot be expected to take place. Under these circumstances it is, I think, best to apply from the very first, water-dressing, so as to allow a vent for the discharges that take place after the first four-and-twenty hours. After the position of the limb has been thus attended to, an endeavor must be made to moderate the local inflammatory action, and to lessen constitutional irritation. The local action may be moderated by the use of irrigation (fig. 45), and by the application of cold evaporating lotions to the part, which should be elevated and but lightly covered, the bed-clothes being well raised by means of a cradle, so as not to press on the limb, and to allow space for the evaporation of the cold lotion; care being taken, at the same time, that the bandages be applied very loosely, merely with a sufficient degree of force to retain the limb upon the splint, as inflammatory infiltration that might rapidly induce strangu- lation of the part is apt to ensue. The constitutional irritation must be subdued by the administration of opiates, together with an aperient, on the morning following the accident, which must be repeated from time to time during the first few days. Moderate antiphlogistic regimen must be had recourse to, and the patient be disturbed as little as possible. In many cases suppuration rapidly sets in, and if the patient be addicted to drinking, the constitutional disturb- ance soon assumes the irritative form; under these circumstances, it is of great moment that support, and even stimulants, be freely given; they must be allowed from the very first, and increased in proportion to the depression of the patient's strength, or as symptoms of nervous irritation come on. If there be much extravasation of blood into and bruising of the soft parts, great tension of the limb, followed by unhealthy suppuration and sloughing, will take place in the neighborhood of the wound; free incisions are then required to remove the tension and strangulation of the tissues, and by letting out the broken-down blood and pus to lessen the risk of the occurrence of gangrene. So soon as suppuration is fairly established, a light poultice or thick water-dressing, should be applied, and the burrowing of matter prevented by making counter-openings where necessary, by the application of a compress, and by attention to the position of the limb. The fracture apparatus must be kept scrupulously clean, especially in summer; the bandages changed as often as soiled, and the pads well protected with oiled silk. During this period various complications, such as erysipelas, inflammation of the absorbents and veins, and low forms of pneumonia, are apt to occur, requiring special consideration and treatment; so also, if the discharge be abundant, hectic, with its sweats and gastro-intestinal irritation, may come on, requiring full support of the powers of the system, and the administration of the mineral acids and other remedies, according to circumstances. As the confinement to bed is necessarily very pro- longed in these cases, often extending through many weeks and months, the state of the patient's back should be attended to, and he should early be placed upon a water-cushion, or hydrostatic bed, lest sores supervene. As the wound gradually heals, water-dressing must be substituted for poultices, so as not to sodden the parts and encourage suppuration, and in time the red or blue wash for the water-dressing. The bone will often be observed lying white and bare, bathed in pus, at the bottom of the wound. But though in this apparently un- favorable condition, it may recover itself; lymph gradually being deposited in points on its surface by the action of its own vessels, and this becoming vascu- larized, covering it with a layer of florid granulations. In other cases, necrosis SECONDARY AMPUTATION IN FRACTURES. 203 to a greater or less extent will take place, and perfect consolidation does not occur until the bone has separated. In some instances, a large quantity of pro- visional callus is thrown out, in which the necrosed bone is implicated, and then the process of separation becomes extremely tedious and protracted, and ampu- tation may not uncommonly become necessary, from the powers of the patient being unable to bear up in so prolonged a struggle. So soon as some consolida- tion has taken place, the limb should be firmly put up in gutta-percha or leather splints, with a starch bandage, so as to enable the patient to be got out of bed, to change the air of his room, and thus to keep up his general health. In fitting these splints, care must be taken to make an aperture opposite the wound, through which it may be dressed (Fig. 82). The time required for the proper consolidation of a compound fracture varies greatly, according to the amount of injury done to the bones and soft parts, the age and constitution of the patient. Under the most favorable circumstances, it requires double or treble the time that is necessary for the union of a simple fracture. Much stiffness of the limb from rigidity of the muscles and tendons will continue for a considerable length of time; this may gradually be removed by frictions and douches. Secondary amputation may become necessary from the occurrence of trau- matic gangrene, when it must be done in accordance with the principles already laid down when speaking of that operation; but more frequently it is required from failure of the powers of the patient in consequence of irritative and asthenic fever, induced by the general disorganization of the limb, or by hectic resulting from profuse suppuration and slow necrosis of the bones. Under these circumstances, the constitution suffers from the local irritation which is the source of the wasting discharge, but by removing this in time, and seizing an interval in which constitutional action may have been somewhat lessened, the patient's life will in all probability be preserved; the results of secondary amputation for compound fracture under these conditions being by no means unfavorable. Indeed, it is remarkable to see how speedily the constitutional irritative and hectic symptoms subside after the removal of the source of irri- tation, the patient often sleeping well, and taking his food with appetite the day after the operation. The proper period to seize for the performance of secondary amputation in the earlier stages of the injury is often a most critical point. As a general rule, it may be stated, that if the limb be not removed during the first twenty-four hours, eight or ten days must be allowed to elapse before the operation is done; as during that time constitutional irritation and suppurative fever are of too general and active a character, to render fresh shock to the system admissible. But when once the actions appear to tend to localize themselves, the suppu- ration becoming more abundant, the redness extending but slowly, and the con- stitutional symptoms merging into an asthenic form, then the limb may be removed with the best prospect of success; the more the action is localized the better being the chance of the operation succeeding. In many cases the symptomatic and suppurative fever so rapidly merge into the asthenic form, that the surgeon must seize the best moment he can for the performance of the amputation. Under these circumstances the operation is seldom very successful, the stump becomes sloughy, erysipelas or diffuse in- flammation of the cellular tissues come on, or symptoms of pyemia set in, and the patient speedily dies. In other cases again, there is a marked interval between the stages of the inflammatory and suppurative fever, and the super- vention of the typhoid symptoms, lasting for twelve or twenty-four hours, or even longer. During this the mischief may be looked upon as in a great measure of a local character; the constitution has been disturbed by the set- ting up of the inflammatory action, but this having terminated in suppuration, it has not as yet become seriously depressed by the continued irritation of the 204 FRACTURE S. discharge from the injured limb, or poisoned by the absorption of morbid mat- ters from it. The patient's powers must not, however, be allowed to sink to the last ebb before amputation is performed, as then, if the shock donot destroy life, inter- current and visceral congestion, or some low form of inflammatory mischief, will not improbably prove fatal. Much as "conservative" surgery is to be admired and cultivated, and hasty or unnecessary operations to be deprecated, I cannot but think that the life of the patient is occasionally jeopardized, and even lost, by disinclination on the part of the surgeon to operate sufficiently early in cases of compound fracture, and by too prolonged attempts at saving the injured limb. The success of the operation will in a great measure depend upon the after- treatment of the case. Large quantities of stimulants and support are often required in London practice to prevent the patient from sinking. I have often given with the best success eight or ten ounces of brandy, twelve or sixteen of port wine, with two or three pints of porter in the twenty-four hours after these operations, with beef-tea, arrow-root, or meat, if the patient will take it, and have found it absolutely necessary to do so lest the patient die exhausted. At a later period than this, when some weeks or months have elapsed, and the fracture has not united, the bones necrosing, and the patient being worn out by hectic, amputation must be performed at any convenient moment, and is often then done with great success if if be not deferred too late; for here the mischief is entirely local, and the constitution suffering only by the debility resulting from it, quickly rallies when the cause of this is removed. A fracture is occasionally so badly set that it becomes necessary to break or bend the callus, in order to improve the condition of the limb. When the dis- placement is angular, and the consolidation not very firm, this may be done pretty readily; but if the displacement be longitudinal, and much time has elapsed since the occurrence of the injury, it will be impossible to remedy the deformity. During the first four weeks the bond of union between the frag- ments is so yielding, that the angular displacement may he remedied by putting up the fracture afresh day by day, by the employment of pressure, and by the application of the roller in the opposite direction to that in which it had been previously applied. After this period, the deformity can only be remedied by forcibly bending or breaking the callus, and then putting up the fracture again, when speedy and perfect consolidation will ensue. In this way I have several times remedied fractures that had got into a faulty position, although five or six weeks had elapsed from the occurrence of the injury. UNUNITED FRACTURES AND FALSE JOINTS. Some bones when broken never unite by callus or plastic matter, their frag- ments merely being kept firm by the intervention of the aponeurotic structures of the part, as is the case with the patella. This, which is'owing to a want of apposition of the fragments, and is dependent on the condition of the part, can- not be considered a diseased action. It happens, however, occasionally in fractures of the shafts, or the articular ends of long bones, that proper union has not taken place at the usual time, or does not take place at all. This may be owing to one of three circumstan- ces : lstly, That no uniting material of a stronger kind than fibro-cellular tissue has been formed; 2dly, That the plastic matter that has been thrown out has only developed into fibrous tissue, not having undergone osseous transforma- tion ; or, 3dly, That true bony union has taken place, but, owing to some peculiar state of the patient's health, the callus has become absorbed, and the fracture loosened. In the first and third conditions we have an ununited fracture ; the ends of UNUNITED FRACTURES AND FALSE JOINTS. 205 the bone which are rounded and eburnated being merely connected by, and enveloped in, a loose fibro-cellular tissue. In the second condition we have a false joint, the ends of the bone being tied together by strong fibrous bands. The structure of these false joints, which has been carefully studied by Rokitansky, presents two distinct varieties. In the first, which partakes of the character of a hinge joint, we find that the ends of the fracture are smoothed and rounded, invested with a dense fibrous perios- teum, and united to one another by thick bands of ligamentous tissue, in such a way as usually to admit of considerable lateral movement, though sometimes they are tolerably firm. In the other variety the joint partakes of the ball and socket character, usu- ally to a very imperfect degree, but sometimes in a sufficiently well-developed manner, one end of the bone being rounded and invested by periosteum, the other, cup-shaped, and covered by firm smooth fibroid tissue. The bones are united by a kind of capsule, in which a synovia-like fluid has occasionally been found. The form that the false joint will assume depends on the action of the mus- cles that influence it. Thus, when occurring in the shafts of long bones, when it is subjected to movements of flexion and extension, it will assume the hinge form; whilst when it is seated in the articular ends, where it is more subjected to movements of rotation, it will affect the ball and socket character. The causes of ununited fracture and false joints are constitutional and local. In some cases the constitutional cause appears to be' a cachectic state of the system, occurring from some debilitating disease, such as phthisis, scurvy, or cancer, or from any depressing cause, in consequence of which there is not suf- ficient reparative power for the production or proper development of the plastic matter, by which the fracture should be united. If it have been deposited, it may, under the influence of these constitutional causes, again become absorbed, and the fracture thus be loosened; but in many cases no constitutional cause can be detected, the patient being in excellent health, strong, and robust. In spontaneous fractures, union seldom takes place very readily or perfectly. Pregnancy is said to have a tendency to interfere with the proper union of a fracture; this, however, I consider doubtful, as I have had under my care, and have seen a considerable number of cases of fracture in pregnant women, which united in the ordinary manner. Age does not appear to exercise any influence on the occurrence of disunion in fractures, which is indeed most common in the early and middle periods of life, when fractures are most frequently met with. I have on two occasions, in my own practice, known very firm and perfect consolidation of fracture of the shaft of the femur, take place in women of ninety years of age and upwards. The local causes are various and important. The anatomical condition of the fragments, as regards their vascular supply, is perhaps that on which want of union is most immediately dependent. For proper union to take place, it is ne- cessary that the callus be deposited from both sides of the fracture. If one fragment is so situated* that sufficient blood is not sent to it for this purpose, not only may disunion, but necrosis, occur. This we see exemplified in fractures of the superior articular ends of the humerus and femur. In intracapsular fracture of the anatomical neck of the humerus, the globular head, being de- tached from all its vascular connections, may necrose. In intracapsular fracture of the neck of the femur, the head of the bone still retaining some vascular con- nection through the medium of the ligamentum teres, has sufficient blood fur- nished to it, to prevent its death, but not enough to form callus—hence fibrous union takes place. In the shafts of the long bones the degree of union will be dependent in a great measure on the conditions of the vascular supply to the fragments, through the medium of the nutritious artery. The influence of the rupture of the nutritious artery of the bone by the line of fracture running 206 FRACTURES. across it, and thus interfering with the vascular supply of one of the fragments, has been .investigated by Gueretin; and the occasional occurrence of atrophy of the bone after fracture, has been shown by Curling to be dependent upon the supply of arterial blood through this vessel being interrupted. Gueretin has collected cases that tend to prove the direct connection between the occurrence of ununited fracture, and the want of proper arterial supply to one of the frag- ments. Thus in the humerus the course of the nutritious artery is from above downwards, and of 13 cases of ununited fracture, 9 were found to be situated above the canal in whi#n this vessel is lodged. In the forearm where the nutritious artery passes from below upwards, of 8 cases of ununited fracture, 7 occurred below this vessel, and only 1 above. Mr. Adams has, however, shown that the number and size, as well as position, of the nutrient arteries varies con- siderably, and hence the objection that non-union may occur in a fracture of any part of the shaft of a long bone, whereas the nutritious artery is only found at one spot, can scarcely be considered a very valid one. It is certainly owing in a great measure to this want of vascular supply that intracapsular fractures almost invariably unite by fibrous tissue rather than by bone, and that when bony union takes place, the callus is chiefly formed by the surface connected with the shaft. In some cases of intracapsular fracture of the humerus, no union whatever takes place, the detached fragment necrosing in consequence of its being entirely deprived of all supply of blood. Some bones are much more liable than others to disunion of their fractures. According to the statistics collected by Norris, it would appear that the femur, the humerus, the bones of the leg, and of the forearm, and lastly the lower jaw, are those in which ununited fractures most frequently occur, and that in the order which has been given. The occurrence of ununited fracture is occasionally attributed to the mobility or want of proper apposition of the fragments, and doubtless in some cases it may be so occasioned : but I believe that these causes are not nearly so frequent in their operation as the constitutional and local conditions that have already been pointed out. The interposition of a piece of muscle between the fragments, may occasion disunion. Of this I saw an interesting instance some years ago, in which want of union in a fractured femur was owing to the entanglement of a portion of the rectus muscle between the fragments. The treatment of ununited fracture must chiefly be conducted with reference to the constitutional cause of the disunion, though local measures must not be neglected. If callus have not been formed, or, after formation, have been ab- sorbed under the influence of a cachectic state of the system, the improvement of the patient's health, at the same time that the fracture is put up again firmly, so that the ends of the bone are brought in close apposition, may bring about perfect union. I have lately had under my care at the hospital, a man with ununited fracture of the femur from absorption of the callus four months after the occurrence of the injury, under the influence of incipient phthisis and debility induced by want of food, in whom perfect consolidation of the fracture has taken place, by giving him cod-liver oil and good diet, with rest in bed and a starch bandage to the limb. If there is no very evident cause for the disunion, putting up the fracture firmly in leather or gutta-percha splints, with a starch bandage, and then allowing the patient to move about upon crutches, so that his general health may not suffer, at the same time that a tonic plan of treat- ment is had recourse to, will occasionally suffice. This, however, can only be useful if but a short time, at most some months, has elapsed from the occurrence of the injury. Mr. Smith1 (U. S.) has modified this treatment by putting the limb in an apparatus which combines pressure on the fracture with the power of movement. This plan, though somewhat tedious, occupying several months, appears to be successful, 10 cases out of 14 having been cured by it, 1 [Vide Am. Journal of the Med. Sciences, for January, 1855.] TREATMENT OF UNUNITED FRACTURES. 207 and has the merit of being unattended by danger. In some cases the empirical administration of mercury is attended with success. In a case of ununited frac- ture of the humerus that was admitted into the hospital under Mr. Liston, fif- teen weeks after the occurrence of the injury, union took place within a month by putting up the limb in splints, and salivating the patient. When the dis- union arises from malignant disease nothing can be done. When the disunion has become very chronic, and a false joint has once formed, it will be necessary to have recourse to operative procedure before union can be attained. All operations that are undertaken in these cases are con- ducted on one or two principles; either with the view of exciting such inflam- mation in the false joint and the neighboring tissues, as will lead to the formation of lymph capable of undergoing osseous transformation; or else, by removing the false joint altogether, to convert the case into a recent compound fracture, and to treat it in the same way that such an accident would be managed. It can easily be understood that operative procedures conducted on these principles are of too serious a character to be lightly undertaken, or to be had recourse to until other measures have failed, the mortality following them being, even according to public statistics, considerable; and probably very much greater than has been laid before the profession. Amongst the first set of operations, — those that have in view the excitation of sufficient inflammation to cause deposit of proper plastic matter, — the simplest procedure consists in the introduction of acupuncture needles, or in the subcutaneous section of the ligamentous band with a tenotome. In this way I have known union effected in a patient of Mr. Liston's, who had a false joint in the shaft of the femur, though not until after the fracture had been converted into a compound one, and much danger and suffering incurred. Four years after the consolidation of the ununited fracture, the patient was readmitted into the hospital, under my care, with fracture of the same bone two inches lower down than the former injury, and on this occasion, union took place in the usual manner and time without any difficulty. The introduction of a seton across the false joint, though occasionally suc- cessful, is apt to give rise to dangerous and even fatal consequences, from arterial hemorrhage, erysipelas, diffuse inflammation and suppuration of the limb. The threads must not be left in beyond a few days, when sufficient action will have been induced. A modification of the seton consists in passing a silver wire around the fracture, and by gradually tightening this, to cut through the false joint at the same time that inflam- matory action is excited in it. In performing this operation it must be borne in mind that large arterial branches and even the main trunk, especially in the thigh, may become firmly attached to the callus, so that unless care be taken they may readily be wounded. Dieffenbach has excited the requisite degree of in- flammation by driving with a mallet, three or four conical ivory pegs into holes bored by means of a gimlet or drill, (fig. 84,) in the ends of the fractured bone, which are exposed for this purpose. The soft parts are then laid down over them, and after a few weeks the pegs, which have loosened in consequence of the removal or absorption of their ends, should be taken out. It is not necessary or even desirable to endeavor to pin together the ends of the broken bone, but merely to introduce the pegs into the extremities of both fragments near to the seat of fracture. It is however, especially in ununited fractures of the femur and humerus that this can be successfully done; the irritation of the pegs Fig. 84. 208 FRACTURE S. appearing to occasion an effusion of a large quantity of callus, sufficient for the consolidation of the fracture. The operation of removing the false joint may be performed by ratting down upon it, and resecting the ends of the bones, or else by destroying the articulation with caustic potass. The excision of a false joint is necessarily a dangerous operation, and by no means a successful one; erysipelas, phlebitis, and diffuse suppuration of the bone occasionally supervening. Of 38 cases collected by Norris, in which the ends of the bones were either resected or scraped, 24 were cured, 7 derived no benefit, and 6 died. In those cases that are successful by this method, some shortening of the limb must be expected to result, and if the fracture be very oblique, it would of course be impossible to remove more than a very limited portion of it, and, consequently, very perfect union could scarcely be anticipated. The application of caustics to the exposed bones is so coarse and uncertain a method, as to find but little favor amongst surgeons of the present day. On reviewing the various methods that have been recommended for the re-establishment of union between the separated fragments, it would appear that the excitation of proper inflammatory action, by the introduction of the seton, or by driving in ivory pegs, promises the most satisfactory result. It is by no means necessary to remove the fibrous band that intervenes between the the fragments in case of false joint, for if the proper amount of inflammatory action be set up, this either undergoes osseous transformation, or a sufficient quantity of callus is thrown out around it to consolidate the fracture. If union fails to be accomplished, amputation may be required as a last resource. CHAPTER XV. SPECIAL FRACTURES. ' In considering the nature and treatment of fractures of particular bones, we shall at present confine our remarks to fractures of the face and extremities. Injuries of the bones of the head and spine derive their principal interest and importance, from their complication with lesion of some internal and contained organ; hence the consideration of these can with more propriety be referred to that of these parts. Fractures of the Bones of the Face. — The nasal bbnes, being thin as well as exposed, are not unfrequently broken. When fractured they may remain undisplaced, but are more commonly depressed; the ridge of the nose being beaten in. The swelling and ecchymosis that usually attend this fracture render its detection difficult, and must be reduced before any treatment is adopted. The bone that is depressed should be raised with the broad end of a director, or by the introduction of a pair of polypus forceps into the nostril, which expand in opening, and push it into proper position. If the septum alone be broken, the same treatment must be adopted towards it. Usually, after being replaced, the position is maintained; but in some cases, where there is a tendency to sinking of the nostrils, the introduction of a plug into the nares will be required to replace and retain the bones. The hemorrhage, which is usually pretty abundant, may be stopped by the applica- tion of cold, but occasionally the nostrils require plugging. If the lachrymal bone be broken, together with the nasal, the ductus ad nasum may be obstructed, FRACTURES OF THE BONES OF THE FACE. 209 and the course of the tears diverted. In an injury of this kind I have seen extensive emphysema of the eyelids and forehead occur on the patient attempt- ing to blow his nose. In some cases the injury inflicted to the nasal bone extends through the ethmoid to the base of the brain, and may thus occasion death. This I have seen happen from a severe blow on the face with a piece of wood. The malar and superior maxillary bones are seldom broken unless great and direct violence has been had recourse to, and their fracture is usually accompa- nied by external wound, as in gun-shot injuries of these parts. More commonly the alveolar processes are detached, and the teeth loosened. The treatment then consists in binding the teeth together with gold wire. In some rare cases all the bones of the face appear to have been smashed and separated from the skull by the infliction of great violence. Thus, South relates the case of a man who was struck on the face with the handle of a crane, and in whom all the bones were separated and loosened, " feeling like beans in a bag." Vidal records the case of a man who, by a fall from a great height, separated all his facial bones. In fractures of the zygoma the fragments may be driven into the temporal muscle and produce so much difficulty to mastication, as to require removal. The lower jaw is frequently broken, owing to its prominent situation; though its arched shape enables it to resist all but extreme degrees of violence. Frac- tures of this bone are usually compound, the laceration of the gum causing them to communicate with the external air. And not unfrequently they are commi- nuted as well, but yet from the freedom of the vascular supply to the bone, rapid and very perfect union takes place in it. Fracture of the lower jaw may occur in various situations. I have seen it most frequently in the body of the bone, near the symphysis, extending between the lateral incisors; or between these teeth and the canine. The symphysis itself is not so commonly fractured, the bone being thick in this situation. The angle is frequently broken, but the neck and coronoid process rarely give way. The signs of fracture of the lower jaw are very obvious. The great mobility of the fragments, the crepitus, the irregularity of the line of teeth, and of the arch of the jaw, laceration of and bleeding from the gums, and dribbling of saliva, indicate unequivocally the nature of the injury. The displacement and mobility of the fracture are greater the nearer it is to the symphysis. If the bone happen to be broken on both sides of this line, the middle fragment is much dragged out of place by the depressor muscles of the lower jaw. In fracture about the angle and ramus, the deformity is not so great, owing to the muscles, that coat and protect either side of the bone in this situation, preventing the fragments being displaced. The treatment is simple enough in principle, though often not very easy of accomplishment. It consists in maintaining the parts in apposition by suitable apparatus for four or five weeks, during which time mastication must be inter- dicted, the patient living on sop, soups, and fluid nourishment of all kinds, and talking prohibited. The apparatus that commonly suffices consists of a gutta- percha splint, moulded to the part, properly padded, and fixed on with a four- tailed bandage; the two fore-ends of which are tied behind the neck, whilst the two others are knotted over the top of the head. When the ramus is broken the side of the pasteboard cup splint should be made proportionately long. Any teeth that are luosened must be left in, as they will probably contract adhesions, and fix themselves firmly; and, if necessary, they may be tied to the sound teeth with gold wire, or dentist's silk. When depression, especially near the symphysis, is considerable, a clamp apparatus which fixes the chin and the line of teeth has been invented by Mr. Lonsdale for the purpose of steadying the fragments, and answers the purpose extremely well. [The treatment adopted in this country, in those cases of fracture of the lower maxillary bone, which are attended with but little displacement, consists in the 210 SPECIAL FRACTURES. application simply of retaining compresses and of Barton's or Gibson's bandage for the lower jaw. In oblique fractures accompanied with separation of the fragments, the use of the gutta-percha cup and the same bandage will generally suffice; the retention of the fragments in coaptation may also be materially assisted by the adjustment over the teeth and gums of the silver clamp proposed by Dr. Mutter.] . . . In fractures of the body of the lower jaw by gun-shot injury, there is great comminution and splintering of the bone, followed by copious and fetid dis- charge, which, being in parts wallowed, may reduce the patient to a state of extreme debility. In these cases, Dupuytren recommends the lower lip to be cut through, the splinters taken away, and, if necessary, a portion of the bone resected, so as to convert the wound into one similar to what results after the partial removal of the lower jaw for disease of the bone. Fracture of the os hyoides is of very rare occurrence, and, though usually the result of direct violence, as a forcible grasp, has been seen by Oliver d'Angers to occur from muscular action. The signs are always very obvious, the frag- ments forming a sharp salient angle; there is much pain and irritation, increased by speaking and deglutition. There is usually salivation; and considerable difficulty in breathing may be present. Reduction is accomplished by pressing the fragments into apposition, either externally or by passing the finger into the mouth. Should one piece of the bone be driven much in, it might possibly require to be drawn forwards with a tenaculum. The head should then be fixed by a stiff pasteboard collar to prevent displacement. The Clavicle is often broken, partly owing to its exposure to direct vio- lence, and partly to its action in preserving the shoulder at a proper distance from the trunk, and being the only direct osseous support of the upper extremity, receiving, by transmission through the scapula, every shock that is communi- cated to the hand when the arm is in an extended position; hence blows on the shoulder and falls on the hand are common causes of fractured clavicle. This bone would be more frequently broken than it is, were it not that it resembles two segments of a circle looking in opposite directions, so as to form an 8 shape, which admirably enables it to withstand indirect violence. The clavicle may be fractured in three situations; lstly, and most frequently, the great convexity is broken, the bone bending here when pressed upon from its extremity, the curve becoming increased, and at last giving way; 2dly, it may be fractured nearer the acromion under the acromio-clavicular and coraco-clavicular liga- ments ; and 3dly, its tip may be broken off external to the outermost point of insertion of the trapezoid ligaments between it and the acromion. The signs will depend upon the seat of fracture. When the bone is broken between the conoid and trapezoid ligaments, there is little, if any, displacement, but pain on pressure, some crepitus on moving the shoulders, and slight irregularity in run- ning the finger along the bone. When the fracture is external to the trapezoid ligament, there is a remarkably oblique displace- ig^jj. ment of the scapular fragment, the articular surface of which is turned forwards and inwards, with a slight inclination downwards, nearly at right angles to the rest of the bone, apparently by the dragging of the weight of the shoulder, the point of which, with the scapula, is rounded forwards (fig. 85). When the fracture occurs about the middle of the bone, or at any part on the sternal side of the sca- pular ligaments, there is a remarkable degree of deformity, owing to the displacement of the outer 86 H^h^Cl • fragment in a direction inwards and downwards. y av This displacement is owing to two causes, the weight of the arm dragging the fragment down, and the action of the muscles FRACTURES OF THE CLAVICLE. 211 that pass from the trunk to the shoulder drawing the scapula and the whole of the upper extremity, forwards and inwards towards the mesial line, when the support of the clavicle is removed. The outer extremity of the inner fragment appears to be elevated, the skin being drawn tensely over it; but this is rather owing to the depression of the outer portion of the bone; it is in reality kept fixed by the antagonism between the sterno-cleido-mastoid and great pectoral muscles. On looking at a patient with fracture of the clavicle in this situation, the nature of the injury is at once evident. The flattening of the shoulder with its point approximated towards the sternum, the great prominence formed by the end of the inner fragment over which the skin is tightly stretched, the sudden depression under this, and the crepitus, which can be easily induced by raising and rotating the shoulder at the same time that the elbow is pressed to the side, indicate in the most unequivocal manner the nature of the injury. The atti- tude of the patient is remarkable; he sits, leaning his head down to the affected side, so as to relax the muscles, and supports his elbow and forearm in the sound hand, in order to take off the weight of the limb. Fracture of the clavicle in infants not unfrequently occurs, and is apt to be overlooked. The child cries and suffers pain whenever the arm is moved. On examination, an irregularity with some protuberance will be felt about the centre of the bone. Comminuted fracture of the clavicle from direct violence is often a serious accident, as the subclavian vein and subjacent plexus of nerves, or the upper part of the chest, may be seriously injured as well. In a case of this kind that was under my care some time since, the subclavian vein was apparently wounded, great extravasation of blood taking place about the shoulder and neck, and the circulation through the veins of the arm so much interfered with as to threaten gangrene. The case did perfectly well, however, by the continuous application of arnica lotions to the shoulder, and attention to the position of the arm. Treatment—When the fracture occurs at the tip of the acromial end of the clavicle, a figure of 8 bandage round the shoulders, and keeping the arm in a sling, will prevent the tendency to displacement forwards. When the bone is broken underneath the scapulo-clavicular ligaments, there is but little displacement, and the same treatment will suffice. But when the fracture is situated towards the middle of the bone, or indeed at any point to the inside of these ligaments, then the management is more difficult, and there are three principal indications to be attended to, in order to correct the triple displacement of the scapular fragment. By placing a thick, wedge-shaped cushion with its broad end upwards in the axilla, and then bringing the elbow closely to the side, the outer fragment is drawn outwards, and by pressing the elbow well backwards, the tendency to rotation forwards of the shoulder is removed, and the broken bone brought into proper position. By elevating the shoulder, and taking off the weight of the arm by means of a short sling that passes well under the elbow, the displace- ment downwards is remedied. In applying the necessary apparatus care must be taken to bandage the fingers separately, to pad the palm of the hand with cotton wadding, and to apply a roller up the arm as high as the axillary pad. Before applying the roller, the elbow must always be flexed, otherwise undue and dangerous constriction of the arm may occur. The pad should be firm, made of bed-tick stuffed with bran, six inches long, five broad, and three thick at its upper part; the sling must support the elbow, and the hand should be well raised across the chest, so that the fingers rest upon the upper part of the sternum. The elbow must be kept to the side by a few turns of a roller, or by means of a padded belt. In children, in whom these fractures often occur, there is frequently a difficulty in keeping the bandages properly applied; under these 212 SPECIAL FRACTURES. circumstances the starch apparatus will be found very useful, care being taken to re-apply the apparatus so often as it becomes loose, lest deformity result. It has been recommended to treat fractured [Fig. 87. clavicles occurring in females, to whom any irregularity of union in this situation would be very annoying, by keeping the patient in bed for the first two or three weeks. [In fig. 87 is given a representation of the well-known apparatus of Dr. Fox, of Philadel- phia, for the treatment of fractures of the clavicle. This dressing it will be seen is com- posed of a stuffed muslin collar for the sound shoulder, and of a firm wedge-shaped pad and sling for the injured arm. The tapes from the sling are attached in front and behind to the collar, which serves as the point of resistance. This apparatus has been subject to many modifications; the most valuable of which perhaps are those of Drs. Hamilton, Levis, and Bartlett.] Fractures of the Scapula.—Fracture of the body of the scapula is not very com- monly met with, and when it occurs, being always the result of considerable direct vio- lence, it is usually associated with serious injury to the subjacent ribs and trunk. The thick layer of muscles overlying this bone not only protects it, but prevents displacement, and renders the de- tection of its fracture difficult. The fracture usually takes place across the bone, immediately below the spine, but occasionally it may be split longitudi- nally or starred. If ascertained, it should be treated by the application of a body-bandage. FRACTURES IN THE VICINITY OF THE S HO ULD ER-JOINT. These fractures are of common occurrence, and may happen either in the bony points of the scapula that overhang this articulation, or else in the upper end of the humerus. Not unfrequently there is double fracture in the neigh- borhood of this articulation; thus the acromion may be broken as well as the neck of the humerus. These complications necessarily throw some difficulty in the way of the diagnosis of these fractures. In many cases, also, the amount of contusion, and the rapid swelling that takes place, obscure the nature of the injury. The acromion, forming as it does the very tip of the shoulder, is more fre- quently broken than any other of the bony structures in this neighborhood. The signs of this fracture are very obvious; when the acromion is broken off near its root, the arm hangs as a dead weight by the side, and the patient, feeling as if his arm were dropping off, supports it with the other hand. There is flattening of the shoulder, which is most marked by looking at the patient from behind; and the head of the humerus can be felt somewhat lower in the axilla than natural. On running the finger along the spine of the scapula, a sudden inequality in the line of the bone can be detected, and on raising the elbow and rotating the arm, crepitus can be felt, the rounded outline of the shoulder being restored. In many cases the tip of the acromion only is broken off. When this hap- pens, the nature of the injury may be suspected by the patient being unable to raise his arm to a level with his head, so as to touch the crown, owing to FRACTURES OF THE HUMERUS. 213 some of the fibres of the deltoid having lost their points of attachment; and it may be determined by the existence in a minor degree of some of the preceding signs, which prevent the accident being confounded with paralysis of the del- toid from contusion. The treatment consists principally in raising the elbow, so as to take off the weight of the limb, and to push up the acromion by the head of the humerus. At the same time a pad may be placed between the elbow and the side, in order to direct the arm somewhat upwards and inwards, and the limb must be fixed in this position by a bandage and sling. The union may take place either by bone or ligament. The coracoid process is but seldom broken; never, indeed, except by very direct violence. There is in the museum of the University College a prepara- tion showing a fracture of the base of this process, implicating and extending across the glenoid cavity. The attachment of such powerful muscles as the pectoralis minor, biceps, and coraco-brachialis would displace the fragment con- siderably, were it not that it is kept in position by the ligaments to which it gives insertion, and whose fibres are expanded over it. The only treatment that can be adopted is to put the arm in a sling, and fix it to the side. Fracture of the neck of the scapula very rarely occurs, and there can be little doubt that Sir A. Cooper and Mr. South are correct in stating, that cases so described, are, in reality, instances of fracture of the upper end of the humerus. There is, according to Mr. South, no preparation in any museum in London illustrating fracture of the neck of the scapula. Indeed, on looking at the great strength of this portion of the bone, and the way in which it is protected by the other parts about the shoulder, it is difficult to understand how it can be broken, except by gun-shot violence. Fractures of the humerus. — In studying the fractures of the humerus, we must divide that bone into three parts, — the upper articular end, the shaft, and the lower articular extremity. Fracture of the upper articular end of the humerus not unfrequently occurs, constituting an important class of injuries which have been carefully studied by Sir A. Cooper, and more recently by Mr. R. W. Smith, whose work on frac- tures deserves the attentive perusal of every practitioner. Five kinds of fracture of the humerus are met with in the immediate vicinity of the shoulder-joint. Two of these are intracapsular, viz., simple fracture of the anatomical neck, and impacted fracture of this portion of the bone. The remaining three are extracapsular, viz., fractures of the surgical neck, — simple, and impacted; and separation of the great tubercle from the head of the bone. Intracapsular fractures of the neck of the humerus. — When the fracture occurs at the anatomical neck, the head of the bone is detached from the tu- bercles, a little above, or, at the line of insertion of the capsule. These frac- tures are occasioned by severe falls on the shoulder, and are most frequently met with in adults. The signs of this injury are by no means very distinct, though much light has been thrown upon them by the recent labors of Mr. Smith. There is loss of motion in the shoulder, with some swelling and considerable pain; but there is some deformity about the shoulder, and an irregularity, produced by the upper end of the lower fragment, can be felt towards the inner side of the joint; crepitus is easily produced; and there is, on measurement from the acromion to the olecranon, shortening to the extent of about one-third of an inch. When this fracture is impacted, the upper fragment penetrates the lower one. In consequence of this, the axis of the humerus is directed somewhat inwards towards the coracoid process: here also some irregular osseous swelling may be 214 SPECIAL FRACTURES. detected. The head of the bone can be felt in the glenoid cavity, but it is not in the axis of the limb, the elbow projecting slightly from the side, there being at the same time a hollow under the acromion. There is consequently more deformity about the joint in the impacted than in the simple intracapsular frac- ture, with the same impairment of motion, but only slight crepitus on firmly grasping the shoulder and rotating the elbow. In fracture of the anatomical neck of the humerus the portion of bone broken off is truly a foreign body in the joint, and being unconnected with any liga- mentous structure, may perish, and thus give rise to destruction of the articu- lation. When this does not take place it is probable that impaction of the fragment has occurred, and that thus its life is maintained; or it may happen, as Mr. Smith supposes, that its vitality is occasionally preserved in consequence of some partial union being kept up between it and the rest of the bone by untorn shreds of capsule. In either case the principal reparative efforts are made by the lower fragment, which deposits callus abundantly. Treatment.—As there is often much swelling from contusion in these cases, local antiphlogistic treatment by means of leeches and evaporating lotions should be had recourse to, for a few days. A pad may then be placed in the axilla, and a leather or gutta-percha cap fitted to the shoulder and upper arm, the limb having previously been bandaged. The hand must be supported in a sling, and the elbow fixed to the side. In examining and reducing these intracapsular fractures, no violence should be employed, lest the impaction of the fragment be disturbed, or portions of untorn capsule, on which the ultimate osseous repair of the injury is dependent, be broken through. Extracapsular fractures of the neck of the humerus. — In these injuries, the bone is broken through the surgical neck, or that portion which is below the tubercles, but above the insertions of the pectoralis major, latissimus dorsi, teres major, and deltoid muscles. This accident may occur in children as well as in adults; in the former the separation taking place through the line of junction between the epiphysis and the shaft of the bone. In this fracture there is double displacement; the head of the bone and upper fragment are rotated outwards, being under the influence of the muscles inserted into the great tubercle, whilst the shaft is drawn upwards and inwards under the cora- coid process, by the muscles going from the trunk to the arm, and by the flexors of the limb. The signs of this fracture are sufficiently obvious. The glenoid cavity is filled by the head of the bone, which can be felt in it. Below this there is a depression; crepitus is easily produced, and there is great mobility of the lower fragment, and shortening of the limb to the extent of from three-quarters to one inch; but the most remarkable sign is the prominence formed by the upper end of the shaft of the humerus, which projects under the integuments, and can readily be felt under the coracoid process, especially when the elbow is pushed upwards and rotated. The axis of the bone is also directed obliquely upwards and inwards towards this point. In consequence of this fragment, which is often very sharp and angular, irritating the nerves of the axillary plexus, a good deal of pain is complained of in the"arm and fingers. This sign, however, is not met with in children, owing to the greater smoothness of the fractured surfaces. The impacted extracapsular fracture of the neck of the humerus has been especially treated of by Smith in his very excellent work on fractures. In this injury the superior fragment being penetrated by the inferior one, the continuity of the bone and its firmness are in a great measure preserved; lience, the usual signs of fracture, such as mobility, displacement, and crepitus, are not readily obtainable, and indeed the signs of this injury are chiefly negative. Thus, there is impairment of motion, slight deformity about the joint and upper part FRACTURES OF THE HUMERUS. 215 of the arm, and some crepitus; but only obtainable with difficulty, and by firmly grasping the head of the bone whilst the elbow is being rotated. The treatment usually recommended consists in bandaging the limb, putting a pad in the axilla, a leather or gutta percha cap over the shoulder, bringing the elbow well to the side by means of a bandage, and supporting the hand only in a sling, so that the weight of the arm may be allowed to drag on the lower fragment, and thus lessen the displacement. In the management of these fractures, I have found a very convenient r~\ apparatus to consist of a leather splint about two feet long by six inches broad, bent upon itself in the middle, so that one half of it may be applied lengthways to the chest, and the other half to the inside of the injured arm, the angle formed by the bend, which should be somewhat obtuse, being well pressed up into the axilla. In this way the limb is well steadied and the tendency to displacement inwards of the lower fragment corrected. In some cases fracture of the neck of the humerus is followed by atrophy of the bone, though good union has taken place. Compound fracture of the surgical neck of the humerus is not of common occurrence. Recently I had a ease under my care in which the accident happened to a lad from a fall out of a window. The fracture was transverse and the upper extremity of the lower fragment protruded through the deltoid to the extent of an inch and a half. It was reduced with difficulty; as great irritation was set up around the seats of injury, and as there was a tendency to protrusion of the upper extremity of the lower fragment, this was turned out by enlarging the wound, and about an inch and a half of it sawn off. Union took place between the fragments, and recovery was effected with a very perfect arm. Separation of the great tubercle of the humerus occasionally occurs from falls and blows upon the shoulder; but more commonly as the result of the violent action of the three external rotator muscles, which are inserted into it. In this injury there is a double displacement; the tubercle is carried upwards and outwards away from the head of the bone, and under and external to the acromion process; the head is drawn upwards and inwards by the muscles passing from the trunk to the arm, as well as by the flexors of the arm, in such a way that it lies upon the inner edge of the glenoid cavity under the coracoid process, and is indeed almost luxated. The consequence of this double dis- placement is a great increase in the breadth of the shoulder, which is nearly double its natural size; on examination a rounded tumor, the head of the bone, movable on rotating the arm, can be felt under the coracoid process, whilst another osseous mass, the great tubercle, may be felt at the outer and back part of the joint; between these a sulcus is perceptible, and crepitus may be felt by bringing the two portions of bone in apposition and rotating the arm. This accident, which is of rare occurrence, has been most carefully described by Guthrie and Smith, to whom a knowledge of its pathology is due. The principle of treatment consists in an attempt to bring, and retain the detached tubercle in contact with the head of the bone; this may be done either by mechanical means, or by relaxation of the muscles. The treatment by mechanical means consists in placing a pad in the axilla, and bringing the elbow to the side so as to throw out the head of the bone, at the same time that, by means of a compress, the tubercle is pressed into proper position, the arm being supported in a sling. The treatment by relaxation of the muscles consists in elevating and extending the arm from the trunk; in carrying .this out, it is necessary that the patient be confined to bed, the arm being supported on a pillow. Fractures of the shaft of the humerus are usually somewhat oblique from above, downwards and outwards. The nature of the accident can be at once detected by the great mobility of the fragment, the ready production of 216 SPECIAL FRACTURES. crepitus, and the other ordinary signs of fracture. The displacement usually consists in the lower fragment being drawn upwards and to the inner side of the upper one, which is often somewhat everted. The treatment is of the simplest character, flexing the elbow, bandaging the arm, and the application of two or three well-padded splints, the inner one of which should be rec- tangular, being all that is necessary. In applying a splint to the inner side of the arm, care must be taken that it do not press upon the axillary vein, lest oedema of the limb occur. FRACTURES IN THE VICINITY OF THE ELBOW-JOINT May occur through any of the osseous prominences in this situation. They are very commonly complicated with dislocation, with considerable contusion of and injury to the joint, or perhaps with comminution of the bones and considerable laceration of the soft parts covering them. In most cases swelling speedily comes on, tending to obscure materially the nature of the injury. Fractures of the lower articular end of the humerus.— The sepa- ration of the lower epiphysis of the humerus in children before its ossification is complete, is by no means an unfrequent accident, the fragment being carried backwards, with the bones of the forearm connected with it, so as to cause considerable displacement posteriorly. It may readily be displaced, but slips out of its position again, with crepitus, so soon as it is left to itself. A transverse fracture of the lower end, of the humerus, just above the elbow, occasionally occurs in adults. In these cases the dis- placement backwards of the forearm and lower frag- ment, the pain and crepitus, indicate the nature of the accident. Fracture of either condyle of the humerus may arise from blows and falls on the elbow. There is considerable pain about the seat of the injury, but usually not much displacement, unless, as in fig. 87, there is a transverse fracture as well. Crepitus, how- ever may readily be felt by rotating the radius, if it be the external condyle that is injured; or by flexing and pronating the forearm, if it be the internal con- dyle that has been detached. The treatment of all these injuries must be con- ducted on very similar principles. The swelling and inflammatory action, which rapidly supervene, usually require local antiphlo- gistic treatment, the application of cold lotions, or of irrigation, the arm being flexed, and supported in an easy position on a proper splint. After the subsi- dence of the swelling, the fracture, whatever be its precise nature, is best main- tained in position by being put up in angular splints, the forearm being kept in the mid-state between pronation and supination, and well supported in a sling. It is in these particular fractures that passive motion, if it ever be employed, may be had recourse to, a tendency to rigidity about the joint being otherwise often left. The motion should be begun in adults at the expiration of a month or five weeks; in children at the end of three weeks after the occurrence of the accident. ^ [In fractures involving the articulation of the elbow joint, the main difficulty in the treatment arises from the nature of the displacement of the lower frag- ments of the humerus. In consequence of the action of the muscles which pass from the arm to their insertion upon the forearm, viz., the biceps, triceps, and brachials anticus, there is a constant tendency to retraction upwards of the forearm, and necessarily a corresponding displacement of the lower fragments FRACTURES OF THE ARM. 217 of the fractured bone. The indication in the treatment is therefore evidently —to keep up a proper degree of extension of the forearm, and thus to prevent the displacement above described. This we believe can best be accomplished by the use of the splint recommended by the late Dr. Hewson. This splint is angular, with a flexible joint, and so carved as to fit with accuracy upon the anterior portion of the arm and forearm. By this means a sufficient degree of extension of the forearm is obtained, and at the same time all the tendency to excoriation over the condyles, so often observed after the application of the lateral angular splints, prevented.] The only fracture of the bones of the forearm that commonly occurs in the vicinity of the elbow-joint, is that of the olecranon; this may happen from falls upon the elbow, or from muscular action. The displacement is usually considerable, the fragment which is detached being drawn upwards by the triceps muscle. Occasionally, however, when the ligamentary expansion of the tendon of this muscle is not torn through, there is but little separation of the fragments. In the majority of cases, as it takes place from direct violence, there is much swelling about the joint, and not unfrequently the fracture is compound. The treatment consists in keeping the arm extended for about three weeks, by means of a light wooden splint applied along its anterior aspect; at the end of this time it may be gradually flexed. When the separation of the fragments is considerable, bony union does not take place; but when the tendinous expansion of the triceps has not been torn, the fracture unites by osseous deposit. Fracture of the coronoid process is an accident of very rare occurrence, but would occasionally appear to happen, by falls upon the palm of the hand, the forearm being forcibly driven backwards. It may occur from the contraction of the brachialis anticus muscle, as in the case of a boy; reported by Mr. Liston, who, by hanging from a high wall for too long a time, met with this fracture. When it exists, the forearm is dislocated backwards, crepitus being detected as it is replaced in position. The treatment consists in flexing the elbow, placing the arm in a sling, and keeping the joint quiet. Union takes place by ligament and not by bone. Fractures of the middle of the forearm are of very common occurrence, both bones being usually broken, with much shortening, angular displacement, and crepitus. Occasionally one bone only is fractured, from the application of direct violence. When this is the case, more attention will be required in establish- ing the precise nature of the injury. The treatment is simple; a splint somewhat broader than the arm, should be placed on either side of it, and a narrow pad laid along the interosseous space, in order that the patency of this may be preserved; no bandage should be placed under the splint. If masses of callus happen to be thrown out across this interval, the prone and supine movements of the hand will be lost, and the utility of the limb greatly interfered with. Cejmpemnd fractures of the elbow-joint are necessarily serious accidents. If the articulation be simply opened with little laceration of the surrounding soft parts, and no comminution of the bones, the limb may very commonly be pre- served by the employment of active antiphlogistic treatment. If the bones be much shattered, the soft parts not being seriously implicated, removal of the splinters, and more or less complete resection of the injured joint, will enable the surgeon to save the rest of the limb. But if the soft parts be extensively contused and torn, as well as the bones comminuted, amputation of the arm may be required. Compound fractures of the forearm seldom give much trouble or require am- putation, but they very commonly lead to obliteration of the interosseous space, and thus impair the after utility of the limb. Fractures of the lower extremity of the radius, near the wrist, are 218 special fractures. Fig. 89. of common occurrence, from falls upon the palm of the hand, giving rise to very considerable and remarkable displacement, which has often been mistaken for dislocation of this joint. The importance of these fractures, not only in a diagnostic point of view, but also in reference to their treatment, has caused them to be carefully studied by surgeons, and their nature and pathology have been especially investigated by Collis, Goyrand, Voillermier, Nelaton and Smith. The signs of a fracture of the radius in the neighborhood of this joint are so peculiar, that, when once seen, they may always be recognized without difficulty as diagnostic of the injury. The deformity occasioned by this accident gives rise to a remarkable undular distortion of the wrist. On looking at the injured limb sideways, it will be seen that there is a considerable dorsal pro- minence apparently situated on the back of the carpus. Immediately underneath this, on the palmar aspect of the wrist, just opposite the annular ligament, there is a remarkable hollow or arch most distinctly marked at, and indeed confined to, the radial side of the arm; a little above this, that is to say, on the lower part of the palmar aspect of the forearm, there is another rounded prominence, not nearly so large or distinct however as the one on the dorsal aspect. On looking at the back of the hand it will be seen to be placed somewhat obliquely to the axis of the fore- arm, the ulnar border being somewhat convex, and the styloid process of this bone projecting sharply under the skin (fig. 89). The radial side of the wrist is, on the contrary, somewhat concave, appearing to be shortened. The pain about the seat of injury is very severe, and is greatly increased by moving the hand, especially by making any attempt at supination. The hand is perfectly useless, the patient being unable to support it. All power of rotating the radius is lost, the patient moving the whole of the arm from the shoulder at once, and thus apparently, but not really, pronating and supinating it. Crepitus can often be felt, but in some cases the most careful examination fails to elicit it, unless the hand be very forcibly drawn downwards and then rotated. This fracture usually occurs from half an inch to an inch above the articular surface of the radius. The cause of the particular deformity that is observed, and indeed the general pathology of the injury, has been the subject of much discussion, in a great measure owing, I believe, to the opportunity of dissecting recent fractures of this kind being not very frequent. Some years ago I had an opportu- nity of dissecting and carefully examining the state of a limb in a woman who died in University College Hospital, twelve days after meeting with this accident. On examining the left arm, which presented all the signs of this injury in a marked degree (fig. 89), a transverse fracture of the radius was found about an inch above its articular surface. The lower fragment was split into three portions, between which the upper fragment was so firmly impacted to the depth of more than half an inch as to require some force in its removal. The three portions into which the lower fragment _ was split were of very unequal size; the two posterior ones being Bmall, consisting merely of scales of bone, the third fragment, the largest comprising the whole of the articular surface of the radius, which was souie- Fio. 90. FRACTURES OF THE RADIUS. 219 what tilted upwards and backwards. To this fragment were attacned the supi- nator longus, and the greater part of the pronator quadratus; the ligaments and the capsule of the joint were uninjured. This case presented the appearances usually met with in this kind of injury, the lower fragment being displaced in such a way that its articular surface looks slightly upwards, backwards, and somewhat outwards, so as to be twisted as it were upon its axis (figs. 90, 91). The upper frag- ment is always found in a state of pronation, and in many cases is driven into and firmly impacted in the lower one. To what is this displacement of the lower fragment due ? Is it to muscular action, or to the peculiar manner in which the two fragments are locked into one another? Muscular action cannot, I think, be considered the sole, or indeed the chief cause of this deformity, for although the supinator longus is attached to the lower fragment, and with the radial extensors would influence the position of this portion of the bone, yet it must be borne in mind that their antagonists, the pronator quad- ratus and the flexor muscles of the wrist, are likewise attached to, and exercise their action directly upon this fragment, and would have a tendency to counterbalance the action of the supinators and extensors. These mus- cles also are by no means powerful, and would certainly not be able to withstand ordinary efforts at remedying the displacement, which in many cases are unsuccessful. That the deformity is the result of impaction, I feel convinced, notwithstanding the elaborate argu- ment of Mr. Smith in opposition to this view, and my conviction is founded on an examination of several specimens of consolidated fracture of the radius pre- served in the different collections in London, upon the dissection of the case already alluded to, and upon the difficulty in any other way of accounting for the occasional impossibility of properly reducing these fractures. The great traction that is usually required to remove the deformity, and the absence of distinct crepitus in some cases, until after forcible traction has been employed, also indi- cate the existence of impaction. At the same time I do not doubt that it occa- sionally happens that these fractures are not impacted; this would appear to be the case in those instances in which crepitus is easily detected, and the fracture readily reduced. The mode in which the impaction and deformity occur, appear to me to be as follows. When a person falls on the palm of the hand, the shock, which is principally received on the ball of the thumb, and the radial side of the wrist, is not directed immediately upwards in the axis of the radius; but the force impinging in a direction obliquely from before backwards, and from without inwards, as well as from below upwards, has a tendency to rotate the lower fragment on its own axis, and to tilt the articular surface somewhat upwards and outwards. As the upper fragment descends, its posterior surface of com- pact tissue is forced into the cancellous structure of the lower fragment, to such a depth as will admit of the two anterior portions of compact tissue coming in contact, and thus the upper line of compact tissue is driven into the lower fragment to an extent corresponding to the degree with which the fragment is rotated upwards and backwards. If the bone be brittle, or the force be conti- nued after this amount of impaction has taken place, the lower fragment will be splintered. The prominence of the styloid process of the ulna, is the result of the short- ening of the radial side of the wrist and hand consequent upon the impaction. Besides this injury, Mr. Smith has described a fracture of the lower end of the radius in consequence of falls upon the back of the hand, in which the infe- 220 SPECIAL FRACTURES. rior fragment is displaced forwards. In these cases the character of the deform- ity indicates the nature of the injury. It can readily be reduced, with a feeling of crepitation, by traction. In another variety of fracture in this situation, the lower end of the radius and that of the ulna are broken off, resembling very closely dislocation of the wrist backwards. But the fact of the existence of grating, of the ready reduc- tion of the swelling, and of the styloid processes of the radius and of the ulna continuing to be attached to, and following the movements of the carpus, will be sufficient to establish the diagnosis. The treatment of the ordinary fracture of the radius near the wrist is best conducted by the apparatus introduced by Nelaton (fig. 92). This consists of Fig. 92. a pistol-shaped wooden splint, which is placed along the outside of the arm, reaching from the elbow to the extremity of the fingers. Forcible extension and counter-extension should be practised with the view of disentangling the fragments, and removing the dorsal prominence. The splint, thickly padded opposite the lower fragment should then be applied to the outer side of the arm, and the hand being well brought down to its ulnar side, should be band- aged to the bent part of the splint. Another short splint, reaching from the bend of the elbow to the lower extremity of the upper fragment should now e placed along the inside of the arm, after having been well padded along its radial border, so as to counteract the tendency to pronation of this part of the bone. The arm must then be placed in a sling. The fracture unites in the course of a month or five weeks, and passive motion of the joint may then be commenced, but it [Fio. 93. wiH be at least three months before the stiffness of the hand and wrist are so far diminished, even by the use of frictions and douches, as to enable the patient to use the fingers. It sometimes happens that the radius on both sides is broken at the same time in this situation, constituting a somewhat serious condition, inasmuch as the patient is not able to feed or assist himself in any way during the treatment. [In the treatment of fractures of the lower end of the radius, Dr. J. Rhea Barton, of this city, some years since, recommended the application of two straight splints, and of two compresses, one to be applied over the lower frag- FRACTURES OF THE PELVIS. 221 ment, and the other beneath the inferior extremity of the upper. Of late, this dressing has been somewhat superseded by the box splint of Dr. Bond (fig. 93), in which the palm of the hand rests upon a block, the extremities of the fingers remaining free. By retaining the limb in this position the muscles will be relaxed, and no undue pressure exerted upon their tendons. A better chance of escaping permanent stiffness will be afforded; should this, however, result, despite the efforts of the surgeon " the hand will not entirely have lost its uses. For the hand, thumb, and fingers being placed very nearly in the position of their most frequent uses, the interossei, the lumbricales, and the several short muscles of the thumb, will, by causing only a very limited motion, enable the hand to perform very many of its useful functions."] Fractures of the metacarpus and fingers are of so simple a character in every way as scarcely to call for detailed remarks. In the treatment, rest of the part upon a leather or pasteboard splint is all that is requisite. In compound frac- ture of these bones, every effort should be made to save the part; if removal become necessary, it should be to as limited an extent as possible. FRACTURES OF THE LOWER EXTREMITY. In fractures of the pelvis, the danger depends not so much on the extent of the fracture as on its complication with internal injury, and the violence with which it has been inflicted. Fracture may extend in any direction across the pelvic bones, though most commonly it passes through the rami of the pubea and ischium, and across the body of the ilium, near the sacro-iliac articulation In some cases the symphysis is broken through, and in others the fracture extends across the body of the pubes. It occasionally happens that a portion of the crest of the ilium is broken off, but this is of little consequence, even though the bone continues depressed. When the rami of the pubes and ischium, or the whole body of the ilium, are broken through, there is, of course, considerable danger from internal injury. If the patient escape this, the fracture, however extensive it may be, may unite favorably. I had lately a patient under my care at the hospital, with a fracture extending through the rami of the pubes and ischium, and across the ilium, in a line parallel with, and close to the sacro-iliac symphysis, so as completely to detach one half of the pelvis, but who recovered without any bad consequences occurring. The nature of the injury is usually apparent from the great degree of direct violence that has been inflicted upon the part, from the pain that the patient experiences in moving or in coughing, with an impossibility to stand, in conse- quence of a feeling as if the body were falling to pieces when he attempts to do so, with mobility of the part and crepitus on seizing the brim of the pelvis on either side and moving it to and fro. In examining a patient with suspected fracture of the pelvis, care should, however, be taken not to push the investiga- tion too closely, lest injury be inflicted by the movement of the fragments. In those cases, indeed, in which the fracture does not extend completely across the pelvis, or in which it is seated in the deeper parts of the ischium, an exact diagnosis may be impossible. In fractured pelvis, the principal sources of danger arise from injury to the bladder and urethra, with consequent extravasation of urine; from laceration of the rectum, or fracture of the acetabulum; and in examining the pelvis no rough handling should be allowed, lest injury to these parts be inflicted by the fragments. In the treatment, the first thing to be done is to pass a catheter into the bladder, in order to ascertain the condition of the urinary apparatus; if it be injured, measures that will be hereafter described must be had recourse to. The next thing is to keep the part perfectly quiet, so as to bring about union, 222 SPECIAL FRACTURE &. With this view, a padded belt, or a broad flannel roller, should be tightly applied round the pelvis, the patient lying on a hard mattress. The knees may then be tied together, and a leather or gutta-percha splint put upon the hip of the side affected, so as to keep the joint quiet, and to prevent all displacement of the fragment. Fracture of the acetabulum is of rare occurrence, and can only happen when the pelvic bones have been extensively broken. There is a preparation in the University College Museum, exhibiting a comminuted fracture of this articular surface as well as of the ilium. Sanson and Sir A. Cooper have seen the aceta- bulum separated into its three primitive fragments, and the head of the femur driven into the pelvic cavity. As some displacement of the head of the femur would occur in these cases, they might be mistaken for dislocation, more especially as inversion of the foot has been noticed. The crepitus and free mobility would however serve as distinguishing signs. With regard to treatment, the application of a leather splint and broad padded belt, with local antiphlogistic means, is all that can be done. Fracture of the sacrum is an extremely rare occurrence. The only instance with which I am acquainted is in the Museum of the College of Surgeons. The coccyx, though more exposed, is also but seldom broken. When fractured, the pain is usually severe, there being much contusion and inflammation of the ligamentous expansion that covers this bone, so that the patient is scarcely able to walk or to sit. This pain may continue for months and even years. South relates the case of a gentleman who broke his coccyx by sitting on the edge of a snuff-box, and who suffered such severe pain that he was obliged to wear a pad on either tuberosity of the ischium, in order that the coccyx might be in a kind of pit, and free from all pressure when he sat. Fractures of the femur are of great practical interest, from their fre- quency and severity. They may occur in the upper artiqular end of the bone, in its shaft, or in its lower end. In these different situations every possible variety of fracture is often met with. Fractures of the pelvic end of the bone may be divided into those that occur through the neck within the capsule of the joint, — those that occur outside the capsule, and into those that implicate the trochanter alone. Intracapsular fractures of the. neck of the femur are of two kinds, the simple, in which the bone is merely broken across, and the impacted, in which the lower portion of bone is driven into the upper fragment. The intracapsular fracture may also be looked upon as a special injury of advanced life, being but seldom met with in persons under fifty. Thus Sir A. Cooper states that of 251 cases that he met with in the course of his practice, only 2 were in persons below this age. It may, however, happen at an early period of life. Thus, Mr. Stanley has recorded the case of a lad of eighteen, who met with this injury. Another remarkable circumstance in connection with it is, that it commonly happens from very slight degrees of violence, indeed almost spontaneously. Thus, the jarring of the foot in missing a step in going down stairs, catching the toes under the carpet, tripping upon a stone, or entan- gling the foot in turning in bed, are sufficient to occasion it. It is especially in women that this injury is met with. The occurrence of this fracture in old age is owing indirectly to the changes in structure, shape, and position of the head and neck of the femur with ad- vancing years. The cancellous structure of these parts becomes expanded, the cells large, loose, and loaded with fluid fat. The compact structure becomes thinned, and proportionally weakened, especially about the middle and under part of the neck, which, appearing to yield to the weight of the body, is short- ened ; and instead of being oblique in its direction, becomes horizontal, inserted nearly at right angles into the shaft. In consequence of these changes in struc- FRACTURES OF THE NECK OF THE FEMUR. 223 ture and position, it becomes less able to bear any sudden shock by which the weight of the body is thrown upon it, and snaps under the influence of very slight degrees of violence. When it breaks, the capsule may remain uninjured, but the prolongation of it which invests the neck of the bone is usually torn through. In some cases, however, this cervical reflexion is not ruptured, the lower portion of it especially often remaining for some length of time untorn, at last, however, giving way under the influence of the movements of the limb, or by being softened by local inflammatory action. As the violence occasioning the fracture is generally but slight, and as the vascularity of this portion of the bone is trifling in old people, there is but little extravasation of blood. The fragments are almost always so separated that the fractured surfaces are not in apposition: the upper end of the lower fragment is drawn above and to the outer side of the head of the bone, and at the same time is twisted so that its broken surface looks forwards. The head remains in the acetabulum, attached by the ligamentum teres, and sometimes preserving a connection with the lower fragment, through the medium of some untorn portions of the fibrous membrane investing the neck. The capsule is uninjured. Mr. Smith has observed, that in some instances the two fragments become interlocked or dovetailed as it were into one another, in consequence of the line of fracture being irregular and dentated. The signs of an intracapsular fracture of the neck of the femur are altera- tion in the shape of the hip, crepitus and pain at the seat of injury, inability to move the limb, with shortening and eversion of it. These we must consider separately, as important modifications of each are sometimes noticed. The alteration in the shape of the hip is evidenced by some flattening of the part, the trochanter not being so prominent as usual. This process is also ap- proximated to the anterior superior spine of the ilium, and on rotating, the limb is felt to move to and fro under the hand, not describing the segment of a circle so distinctly as on the sound side. The circle described by the trochanter on the injured side is much smaller than that on the sound side. In the sound limb, the trochanter describes the segment of a circle having a radius equal to the length of the head and neck of the bone. On the injured side, the circle has only a radius equal to the length of that portion of the neck that still remains attached to the shaft Fig. 94. of the bone. During this examination crepitus will usually be felt, though this occasionally is very in- distinct-and even absent, more especially if the limb be not well drawn down at the time it is rotated, so as to bring the fractured surfaces in apposition; and much pain is experienced by the patient on any movement of, or pressure upon, the joint. The attitude of the limb is so peculiar, as in general to indicate at once to the surgeon what has happened. There is an appearance of help- lessness about it that is striking. As the patient is lying on his back in bed it is everted, short- ened somewhat, with the knee semi-flexed (fig. 94); on requesting him to lift it up, he makes ineffectual attempts to do so, and at last ends by raising it with the toe of the opposite foot, or with his hands. On being taken out of bed and placed upright, the injured limb hangs uselessly, with the toes pointing downwards, and the heel raised and pointing to the inner ankle of the sound side, the patient being unable to rest upon it. In some cases, however, it happens that after the fracture has occurred, the patient can 224 SPECIAL FRACTURES. lift the limb somewhat, but with much exertion, from the couch on which he is lying; or can even manage to walk a few paces, or to stand for a few minutes upon it, with much pain and difficulty. This is owing either to the cervical reflexion of the capsule being untorn, or else to the fragments not being sepa- rated, having become locked into one another; and it usually occurs in those cases in which the other and more characteristic signs of this fracture are not well marked. Eversion of the limb is almost an invariable accompaniment of this fracture. It is most marked in those cases in which the shortening is most considerable. This eversion has usually been attributed to the action of the external rotator muscles that are inserted into the upper end of the lower fragment. But I cannot consider this as the only, or, indeed, the principal cause, of this posi- tion ; for, not only is it very difficult to understand how these muscles can rotate outwards the limb after their centre of motion has been destroyed by the fracture of the neck of the femur, their action being rather in a direction back- wards than rotatory under these circumstances, but we find that the limb falls into an everted position in those cases in which the fracture being in the shaft, and altogether below the insertions of these muscles, no influence can be exer- cised by them on the lower fragment. I look upon eversion in cases of frac- tured thigh as not a muscular action at all, but as being simply the natural attitude into which the limb falls when left to itself. Even in the sound state, eversion takes place spontaneously whenever muscular action is relaxed, as during sleep, in paralysis, or in the dead body; and in the injured limb in which there is, as it were, a suspension of muscular action, it will occur equally. Indeed, the shortening that takes place will specially tend to relax the ex- ternal rotators, and thus still more prevent their influencing the position of the limb. Inversion of the foot in cases of intracapsular fracture has been noticed in a few cases. I have seen one instance of this; Smith, Stanley, and other sur- geons, also record cases. The cause of this deviation from the usual symptoms of this injury has been a good deal discussed. It has been attributed by some to the cervical ligament not having been torn through at its inner side, but that, as Stanley observes, may prevent eversion, but cannot occasion inversion; by others, to the fact of the lower fragment in these cases being always found in front of the upper one. This circumstance, which is much insisted on by Mr. Smith, appears to me to be rather the result than the cause of the inver- sion, for any rotation inwards of the lower fragment by the adductor muscles of the thigh would have a tendency to draw the upper end of this fragment to the anterior, or, in other words, the inner side of the upper one. I am rather disposed to think that this inversion is owing, in some cases at least, to the external rotators being paralyzed by the violence they receive from the injury that occasions the fracture, and that thus the adductors, acting without anta- gonists, draw the thigh and leg inwards. In the instance that fell under my observation, and in some of those that have been published, the fracture resulted from direct injury to the hip, and was not occasioned by the patient jarring his foot, or by any indirect violence operating at the end of the limb. The shortening in cases of fracture within the capsule seldom exceeds, in the first instance, half an inch to an inch, depending on the extent of the separation between the fragments, and cannot, indeed, in the early periods of the fracture, very well exceed the width of the neck of the bone, as the capsule is usually not torn through. After the fracture has existed some time, the capsule of the joint may yield, allowing greater separation between the fragments, and then it may amount to two, or even two and a half inches. It not uncom- monly happens that the shortening, which is at first but very slight, about half an inch, suddenly increases to an inch or more; this is accounted for on the supposition of the cervical ligament, which had at first not been completely FRACTURES OF THE NECK OF THE FEMUR. 225 ruptured, at last giving way entirely; or, it may be owing to the fragments which were originally interlocked, becoming separated. It is in those cases in which there is but slight separation of the fragments, and consequently little shortening, that the other signs of fracture are not very strongly marked, and that the patient preserves some power over the movements of the limb. The constitutional disturbance in intracapsular fracture of the neck of the femur in old people is often considerable, and the injury frequently terminates fatally, from the supervention of congestive pneumonia, an asthenic state of system, or sloughing of the nates from confinement to bed during treatment. Hence, this injury must always be considered as one of a very dangerous and not unfrequently fatal character. The treatment of these fractures turns in a great measure upon the view that is taken of their mode of union, and on the constitutional condition of the patient. In some cases no union occurs, but the head of the bone remains in the acetabulum, being hollowed into a smooth, hard, cup-shaped cavity, in which the neck, which has become rounded off and polished, is received, and plays as in a socket. The union of the intracapsular fracture of the neck of the femur takes place, however, in the great majority of cases, by fibrous tissue. This is owing to two causes. In the first place, to the circumstance that the fractured sur- faces are not in apposition with one another, which I look upon as the most important; and, secondly, that the vascular supply sent to the head of the bone, consisting only of the blood that finds its way through the vessels of the ligamentum teres, is insufficient for the proper production of callus. In some cases, however, bony union takes place. This can only happen when, in consequence of the cervical ligament being untorn, or the fracture being impacted, the surfaces are kept in some degree of apposition, and the vascular supply to the head of the bone is speedily augmented by the blood carried into it through the medium of the plastic matter that is deposited between the fragments: under no other circumstances is it probable that osseous union takes place in these fractures; hence the unfrequency of its occurrence, there being in all probability not more than eighteen or twenty cases on record as having thus terminated, in this country. When bony union has taken place, the head will usually be found to be somewhat twisted round, in such a way that it looks towards the lesser trochanter, owing to the eversion that has taken place in the lower fragment. As these fractures do not unite by bone, unless the. fragments are in good contact, it is useless to confine the patient to bed for any long period, if the signs, especially the amount of shortening, indicate considerable separation between the fragments, or if the patient be very aged and feeble. Under these circumstances, lengthened confinement to bed most commonly proves fatal by the depressing influence it exercises on the general health, by the intercurrence of visceral disease, or by the supervention of bed-sores. It is, therefore, a good plan to keep the patient in bed merely for two or three weeks, until the limb has become somewhat less painful, the knee being well supported upon pillows. After this time, a leather splint should be fitted to the hip, and the patient be got up upon crutches. There will be lameness during the remainder of life, but, with the aid of a stick and properly adjusted splint, but little inconve- nience will be suffered. When the fragments do not appear to be much separated, there being but little shortening and indistinct crepitus, and more particularly if the patient be not very aged, but in other respects sound and well, an attempt may be made to procure osseous union. This may be done by the application of the long thigh splint, or, if this cannot very readily be borne, by the double inclined plane, with a padded belt strapped round the hips. This apparatus should be kept applied for at least two or three months, when a leather splint may 15 226 SPECIAL FRACTURES. be put on, and the patient be got upon crutches. During the whole of the treatment, a generous and even stimulating diet should be ordered, and the patient kept on a water-bed or cushion. In these fractures of the neck of the femur, the starched bandage will often be found to be most useful. It may be applied as in fractured thigh, but should have additional strength in the spica part, and indeed may be provided with a small pasteboard cap, so as to give more efficient support. In old people, this plan of treatment is especially advantageous, as it enables them to sit up, or even to walk about, and thus prevents all the ill effects of long confinement to bed. The extracapsular fracture of the neck of the femur is commonly met with at an earlier period of life than the injury which has just been described, being most frequent between the ages of thirty and forty. It is the result of the application of great and direct violence upon the hip, and occurs equally in both sexes. This fracture may be of two kinds, the simple and the impacted. In both cases the neck of the bone is commonly broken at, or immediately outside, the insertion of the capsule of the joint. The fracture is almost invariably com- minuted : indeed, I have never seen a case in which the great trochanter was not splintered into several fragments. In many instances the lesser trochanter is de- tached, and the upper end of the shaft injured (fig. 95). This splintering of the trochanter is owing to the same violence that breaks the bone, forcing the lower end of the neck into the cancellous structure of this process, and thus, by a wedge-like action, breaking it into fragments. When the neck continues locked in between these, we have the impacted form of fracture. The signs of extracapsular fracture vary according as it is simple or impacted, but in both cases they partake of the general character of those that are met with in fractures within the capsule. The indi- vidual signs, however, differ considerably from these. The hip will usually be found much bruised and swollen from extravasation of blood, which is usually considerable. The crepitus is very distinct and loud, being readily felt on laying the hand upon the trochanter, and moving the limb. The separate fragments into which the trochanter is splintered may occasion- ally be felt to be loose. The pain is very severe, and greatly increased by any attempt at moving the joint, which to the patient is impossible. The eversion is usually strongly marked, and the position of the limb is cha- racteristic of complete want of power in it. Inversion occurs more frequently in this fracture than in that within the capsule. Smith finds that of 7 cases of inversion of the limb in fractures of the neck of the femur, 5 occurred in the extracapsular fracture; and of 15 cases of extracapsular fracture, this condition was met with in three. When there is much comminution of the trochanter, the foot will commonly remain in any position in which it is placed, but gene- rally has a tendency to rotate outwards. The shortening of the limb is very considerable, being never less than from an inch and a quarter to two inches and a half, and often extending to three or four inches. The impacted extracapsular fracture of the neck of the thigh bone occurs FRACTURES OF THE NECK OF THE FEMUR. 227 when the upper fragment is driven into the cancellous structure of the lower one, remaining fixed there (fig. 96.) The signs of this form of fracture are often of a somewhat nega- tive character, rendering its diagnosis and detection extremely difficult. In many cases there is pain about the hip, with slight eversion of the foot, and some shortening, usually amounting to about half an inch, but never exceeding one inch. There is but little crepitus; in some cases none can be detected, and the patient can frequently raise the foot for a few inches off the couch on which it is laid, and even walk upon it with a hobbling motion, though with much pain. In consequence of the impaction the limb cannot be restored by traction to its proper length, and consequently incurable lameness always results from this injury. The diagnosis of the different forms of fracture of the neck of the thigh bone from one another, and from other injuries occurring in the vicinity of the hip joint, is a matter of considerable importance, and often of no slight difficulty. Between the intracapsular and the ordinary extracapsular fractures there can be no difficulty; all the signs of the latter being so much more strongly marked than those of the former injury, the difference of age and the degree of violence required to break the bone being also important elements in the diagnosis. It is more difficult to distinguish between the intracapsular fracture and the im- pacted extracapsular fracture. In the former case, however, the crepitus and eversion are more marked, and the injury usually occurs from less direct violence than when the fracture is outside the capsule. In the latter case, also, traction cannot restore the limb to its proper length as in the former instance. In severe contusions of the hip there is sometimes eversion of, and inability to move the limb, so that at first sight it might be supposed that the bone was broken. In these cases, however, the absence of shortening and crepitus will always establish the diagnosis. The difficulty is greater, however, in those instances in which the hip-joint having been the seat of chronic rheumatic in- flammation, the limb is already somewhat shortened; here, however, the history of the case, and the fact of the shortening not being of recent occurrence, will be sufficient to establish the nature of the injury. The diagnosis of these injuries from dislocations will be considered in a subsequent chapter. In the extracapsular fracture of the neck of the femur, death not uncommonly results from the se- verity of the injury, the pain and irritation of the fracture and the consequent shock to the system. The great extravasation of blood into the tissues of the limb has been known to be sufficient to account for the fatal result. When the patient lives, bony union takes place, large irregular stalactitic masses being commonly thrown out by the inferior fragment, so as to overlap the several splinters of bone. This callus is most abundant posteriorly in the inter-tro- chanteric space (fig. 97). The treatment of the extracapsular fracture may very conveniently and efficiently be conducted by means of the long splint, a padded belt, if necessary, being strapped firmly round the hips underneath it; or the plan recommended by Sir A. Cooper of placing the patient on a double inclined plane, with both feet and ankles tied together, and a broad belt, well padded, firmly strapped round the body, so as to press the fragments of the 228 SPECIAL FRACTURES. trochanter firmly against one another, will be found an excellent mode of keeping the limb of a proper length, and the fragments in contact. Occasionally the fracture extends through the trochanter major without im- plicating the neck of the bone. Here there is shortening to about three-fourths of an inch, or an inch, with much eversion and crepitus readily felt. This fracture, which unites firmly and well by bone, must be treated in the same way as the last. Compound fractures of the neck of the femur can only occur from bullet wounds. These cases require amputation at the hip-joint, unless the excision of the injured head of the bone be thought worthy of a trial. Fractures of the shaft of the femur are of very common occurrence; every possible variety of this injury being met with here. They are usually oblique, except in children, when they are commonly transverse, and are often commi- nuted, double, or compound. The signs are well marked. There is shortening usually to a considerable extent, with eversion of the limb, crepitus readily produced, and much swelling from the approximation of the attachments of the muscles. The lower frag- ment is always drawn to the inner side of the upper one, and rotated outwards; and when the fracture is high up there is a great tendency to angular de- formity, in consequence of the projection outwards of the lower end of the upper fragment. I have lately had an opportunity of ascertaining by dissection the condition of parts that leads to the eversion and projection forwards of the lower end of the upper fragment in fractures of the femur, in the case of an old man who died about three hours after meeting with a compound comminuted fracture of the middle and lower thirds of the right thigh-bone, and in whom this condi- tion of the upper fragment was very distinctly marked. It was found that the gluteus maximus and medius could be divided without affecting the position of the bone; but when the gluteus minimus was cut across, it yielded somewhat. The pyriformis and external rotators were now felt to be excessively tense, and on cutting these across, the end of the fragment could at once be drawn in- wards, all opposition ceasing. The projection forwards still remained, however, and this, which was evidently due to the tension of the psoas and iliacus mus- cles, yielded at once on dividing them. It would thus appear that there is a double displacement of the lower end of the upper fragments, — outwards, depending on the action of the external rotators, and forwards, owing to the contraction of the psoas and iliac muscles. The treatment of fractures of the shaft of the thigh-bone may be conducted in four different ways; each of which presents advantages in particular forms of these injuries; hence an exclusive plan of treatment should not be adopted. 1st. The fracture may be treated by simply relaxing the muscles of the limb. This is effected by laying it upon its outer side, flexing the thigh well upon the abdomen and the leg upon the thigh, and supporting it in this position by an angular wooden or leather splint, extending from the hip to the knee, or outer ankle, and by a short inside thigh splint. This position I usually adopt in fractures about a couple of inches below the trochanters, in which there is a great tendency to the projection outwards of the lower end of the upper frag- ment, and find these cases turn out better in this way than by any other plan of treatment. 2d. Extension, without regard to muscular relaxation, by means of Liston's long splint and perineal band, will be found a most successful plan of treating fractures in the middle and lower part of the thio-h. In employing the long splint for the treatment^of these fractures, care must be taken that it be of sufficient length to extend about six inches below the sole and nearly as high as the axilla. The perineal band should consist of a soft handkerchief covered with oiled silk, and must be gradually tightened. If FRACTURES OF THE SHAFT OF FEMUR. 229 the perineal band occasion excoriation or undue pressure, so as to necessitate its removal, I have found advantage from keeping up extension with a heavy weight attached to the lower end of the splint. In cases of compound fracture, where the fracture exists in the posterior and outer part of the limb, I have found a long thigh splint, made of oak and bracketed opposite the seat of injury, the most convenient apparatus, enabling the limb to be kept of a proper length, and the wound to be dressed at the same time (fig. 98). Fig. 98. 3d. The double inclined plane is especially useful in many compound frac- tures of the thigh, often admitting of greater facilities for dressing the wound, and the °-eneral management of the case, than any other apparatus that can be applied. 4th. The starched bandage may be employed in most cases. In treating fractures of the shaft of the femur with the starched bandage, the following plan will be found convenient. A dry roller should be applied to the whole of the limb evenly and neatly, which must then be covered with a thick layer of wadding; a long piece of strong pasteboard, about four inches wide, soaked in starch, must next be applied to the posterior part of the limb, from the nates to the heel. If the patient is very muscular, and the thigh large, this must be strengthened, especially at its upper part, by having slips of bandage pasted upon it. Two narrower strips of pasteboard are now placed along either side of the limb, from the hip to the ankle, and another shorter piece on the forepart of the thio-h. A double layer of starched bandage should now be applied over the whole, with a strong and well-starched spica. It should be cut up and trimmed on the second or third day, and then reapplied in the usual way. With such an apparatus as this I have treated many fractured thighs, both in adults and children, without confinement to bed for more than three or four days, and without the slightest shortening or deformity being left (fig. 79). The points to be especially attended to, are, that the back pasteboard splint be very strong, at the upper part especially, and that the spica be well and firmly applied, so that the hip and whole of the pelvis be immovably fixed. [In the treatment of fractures of the thigh, the majority of American sur- geons prefer dressing the limb in the extended position, and for the most part make use of the apparatus of Desault, as modified by Dr. Physick. This is composed of two splints; an external one extending from near the axilla to beyond the foot, and an internal one reaching as high up as the perineum. Both splints should be enveloped in a splint cloth. The perineal or counter- extending band is made of muslin stuffed with cotton, and should be provided at its extremities with strong tapes, or, better still, with a strap and buckle. These should then be carried through mortices in the upper extremity of the lono- splint, and thus counter-extension may be obtained in a line nearly parallel with the long axis of the body. To prevent excoriation of the perineum, it is well to encase the counter-extending band in chamois leather. Extension should be effected by the buckskin gaiter, by a handkerchief, or by means of two long stout strips of adhesive plaster. These should 230 SPECIAL FRACTURES. be applied on either side of the limb in a longitudinal direction, and should reach from above the knee to beyond the sole of the foot; two or three circular adhesive bands will effectually prevent them Fig. 99. from slipping. The remaining portions of the apparatus consist of compresses; of a short anterior splint, should there be any tilting upwards of the superior fragments; and of two junk-bags. These latter should be placed between the limb and the splints, and lateral pressure exerted by means of transverse tapes carried around the whole apparatus. For the purpose of keeping up an accurate degree of extension, it may often be convenient for the surgeon to avail himself of some mechanical contrivance adjusted to the inferior extremity of the long splint. The most eligible of the many inventions for this purpose, are, we believe, the endless screw of Dr. Hamilton, and the extending screw of Dr. T. Hewson Bache. By the me- chanism of the latter, the extending power is so applied as always to act in the line of the longitudinal axis of the limb. If the surgeon in the treatment of a fractured thigh, should desire to dress the limb on an inclined plane, the apparatus of Professor Nathan R. Smith, of Baltimore, will be found to answer the purpose admirably. It is light, portable, and when the limb is suspended, permits of a slight swinging motion. In fractures also of the bones of the leg, it frequently will fulfil every indication.] Fractures in the vicinity of the knee-joint. — The lower end of the femur is not unfrequently broken in a transverse direc- tion, both condyles being detached. This may occur in children from the lower epiphyses not being as yet solidly united to the shaft of the bone. In other cases again the fracture extends through one of the condyles, detaching it from the shaft of the bone. The readiness with which crepitus can be felt, and the line of fracture made out, determines at once the nature of this accident. These cases are sometimes complicated with wound of the knee-joint, rendering ampu- tation necessary. They are best treated on the double inclined plane. I have lately had a case of impacted fracture in this situation under my care, the upper fragment, which was very oblique, being firmly driven into the cancellous struc- ture of the lower one (fig. 99). Fractures of the patella are most frequently met with in men, not very commonly occurring in women, and very rarely in children. I have, however, seen the patella broken in a child under ten years of age. They may be the result of direct violence, when the fracture is often comminuted, or the bone may be broken longitudinally, being split, and the joint injured. But most frequently they occur as the consequence of muscular action; the bone being torn across by the violent effort made by the extensor muscles of the thigh, in the attempt a person makes to save himself from falling when he suddenly slips backwards. All fractures of the patella from muscular action are transverse, the lower portion of the bone being fixed by the ligamentum patellae; the upper segment is torn off by the spasmodic action of the extensors at the moment that the knee is bent, whilst the person is in the act of falling backwards. It not unfrequently happens when one patella has been fractured, that the unsteadi- ness of gait causes the opposite one to be broken by muscular action in an effort to save a fall. The same patella may be broken more than once; in those cases that I have seen, the second fracture has always occurred in the upper fragment, a little above the line of original fracture. fractures of the patella. 231 The signs of this fracture are very evident. When transverse, the separation between the fragments, which is much increased by bending the knee (fig. 100), and the inability to stand or to raise the injured limb, indicate what has happened; when longitudinal or com- minuted, the crepitus and mobility of the frag- ments ; and there is usually considerable swell- ing of the knee-joint in these cases, with perhaps wound of it. When the bone is broken transversely, it very rarely indeed unites by osseous matter, in con- sequence of the wide separation of the frag- ments ; there are, however, two or three cases on record in which this kind of union has taken place in these fractures. In the longitudinal and comminuted fractures, osseous union readily occurs, the fragments remaining in close appo- sition. In the majority of cases of transverse fracture, the fragments remain separated by an interval varying from one-fourth of an inch to an inch, but in some instances the gap is much greater, amounting even to four or five inches. When the separation does not exceed an inch and a half, the gap is usually filled up by fibrous or ligamentous tissue, uniting the fragments firmly. In some of the cases, however, in which the separation be- tween the fragments does not exceed this distance, and in most of those in which it extends beyond it, Mr. W. Adams has found that the fracture is not united by any plastic matter that has been thrown out, but that the fragments are bound together simply by the thickened fascia which passes over the patella, with which is incorporated the bursa patellae. Mr. Adams finds that the apo- neurotic structure thus uniting the fragments may be arranged in different ways. Thus, it may pass between, and be adherent to the anterior periosteal surface of both fragments; or, the connecting aponeurosis maybe reflected over, and be adherent to, both the fractured surfaces; or, lastly, and this is the most frequent form of arrangement, the connecting aponeurosis may pass from the periosteal surface of the upper fragment to the fractured surface of the lower one, to which it becomes closely and firmly united. In the majority of cases, when united by aponeurotic tissue, the fragments gape somewhat towards the skin, coming into better contact posteriorly. Thus, it would appear that a patella fractured trans- versely may unite in two ways; most frequently, by the intervention of thick- ened aponeurotic structure, and, next, by a ligamentous or fibrous band. Of 31 specimens in the London museums, examined by Mr. Adams, it was found that in 15 aponeurotic union had taken place, in 12 ligamentous union, and in the remaining 4 the kind of union could not be determined. The aponeurotic union always leaves a weakened limb and an unprotected joint, for in consequence of the separation of the fragments, the folding in of the fascia, and its adhesion to the capsule of the joint, the fingers can be thrust in between the articular surfaces of the knee. In the treatment of a fractured patella, the principal point to be attended to is, to keep the fragments in sufficiently close apposition for ligamentous union to take place between them. With this view, the upper fragment, which is movable, and has been retracted by the extensor muscles of the thigh, must be drawn down, so as to be approximated to the lower one, which is fixed by the ligamentum patellae. This approximation of the fragments may be effected either by position and relaxation of the muscles, or by mechanical contrivance. By placing the patient in a semi-recumbent position, and elevating the leg con- siderably, so as to relax the muscles of the thigh completely, the upper frag- ment may be brought down to the lower one, and, if necessary, may be retained there, after any local inflammation that results from the accident has been sub- 232 SPECIAL FRACTURES. dued, by moulding a gutta percha cap accurately to and fixing it firmly upon the knee, or by the application of pads of lint and broad straps of plaster. This position must be maintained for at least six weeks, at the expiration of which time the patient may be allowed to walk about, wearing, however, an elastic knee-cap, or, what is better, a straight leather splint in the ham, so as to pre- vent the knee being bent for at least three months. If this precaution be not taken, the union between the fragments, which at first appear to be in very close contact, will gradually lengthen, until in the course of a few months an interval of several inches may be found between them. In these cases, however, even though the separation between the fragments be great, it is remarkable how well the limb may be used, especially on level ground; and with the aid of a knee-cap but little inconvenience is experienced by the patient. Compound and comminuted fractures of the patella, especially if occasioned by bullet-wounds, and injuring the knee-joint, are usually cases for immediate amputation. In most cases of fractured patella the starched bandage will be found a very useful mode of treatment, the patient being with it enabled to walk about during the whole of the treatment. The action of the bandage is much increased, by drawing down and fixing the upper lragment by two broad strips of plaster firmly applied above it. A back splint of pasteboard is required to fix the knee, and a good pad of lint, with a figure of 8 bandage, should be applied above and below the fracture to keep it in position. In several cases I have obtained very close and firm union between the fragments in this way, without confining the patient to bed after the third day. Fractures of the Leg.—The bones of the leg are frequently broken. The tibia, though a stronger bone than the fibula, is most frequently fractured, owing to its being more exposed and less protected by muscles, and receiving more directly all shocks communicated to the heel. The fractures of the upper part of this bone are usually transverse, and result from direct violence; those of the lower extremity, oblique, and proceed from indirect violence. When both bones are broken, the usual signs of fracture, such as shortening, increased mobility at the seat of injury, and crepitus, render the diagnosis easy; but when one bone alone is broken, it is not always a very simple matter to deter- mine the existence of the fracture; the sound bone, acting as a splint, prevent- ing displacement, and keeping the limb of a proper length and steady. If it be the tibia alone that has been broken, the fracture may be detected by run- ning the finger along the subcutaneous edge, until it comes to a point that is somewhat irregular, puffy, or tender, where by accurate examination some mo- bility and slight crepitus may be detected. When the fibula alone is broken, the thick layer of the peroneal muscles, overlaying its upper two-thirds, renders the detection of the fracture difficult, but in the lower third it is easy, by atten- tion to the same signs that occur in fractured tibia. In the treatment of fractures of the leg, M'Intyre's splint will usually be found of great service during the earlier periods, more especially if there be much ecchymosis or extravasation, as it keeps the limb in an easy position, and admits of the ready application of evaporating lotions. After the swelling has subsided, the starch bandage should be applied, and the patient be allowed to move about on crutches. In some cases of fracture of the bones of the leg, however, M'Intyre's apparatus is not applicable. This is more particularly the case when the fracture is very oblique, from above downwards, and from before backwards; under these circumstances, the fragments cannot be got into good position so long as the limb is kept extended and resting on its posterior sur- face ; the bones riding considerably, and one or other of the fractured ends pressing upon the skin in such a way as often to threaten ulceration. In these cases it is, that division of the tendo Achillis has been practised, with a view of removing the influence of muscular contraction. This appears to me, however, fractures near ankle-joint. 233 to be an unnecessarily severe procedure, and certainly was not a very successful one in two cases in which I practised it; for although the tendon was ex- ceedingly tense, but temporary benefit resulted, the displacement returning under the influence of the other muscles inserted into the foot. In these cases the bones may usually be got into excellent position by flexing the thigh well upon the abdomen, and the leg upon the thigh, so that the heel nearly touches the nates, and then laying the limb on its outer side on a wooden leg splint, provided with a proper foot-piece, and keeping it fixed in this position. In some cases the swing-box will be found a useful and very easy apparatus. In some fractures of the leg, the lower end of the upper fragment projects considerably, and cannot be got into proper position so long as the knee is kept bent; but if it be extended, so as to relax the extensors of the thigh, the bone is readily brought into good position. In fractures of the leg, however, as in all injuries of a similar kind, no one plan of treatment should be adopted exclu- sively,, but the means had recourse to should be varied, and suited according to the peculiarities of each individual case. Compound fractures of the leg are best treated on M'Intyre's splint, which admits of proper dressings being applied to the seat of injury more readily than any other apparatus. The details of the treatment of these injuries must be conducted in accordance with those general principles that were discussed in speaking of compound fractures. In fractures of the leg, the starch bandage is especially applicable. It should be applied as follows. A dry roller having been put on to the limb, well covered with wadding, a strong pasteboard splint, four inches broad, and long enough to extend from the back of the knee to six or eight inches beyond the heel, should be applied to the back of the leg. The projecting terminal piece is now to be turned up along the sole of the foot, and two lateral strips adapted to either side of the limb. Over this the starch bandage, single or double, according to the size of the limb, must be tightly applied. After it is dry, about the end of the second day, it must be cut up as represented in Fig. 81, and re-adjusted, and the patient may then walk on crutches with perfect safety. In compound fractures of the leg, a trap may be cut in the bandage, as repre- sented in Fig. 82, through which the wound can be dressed. Fractures in the vicinity of( the ankle-joint are amongst the most common injuries of the bones of the lower extremity. They are usually occa- sioned by twists of the foot, by catching it in a hole whilst running, by jumping from a height to the ground, or off a carriage in rapid motion. These fractures are usually associated with severe strain, or even dislocation, of the ankle. The twist of the foot is almost invariably outwards, the sole remaining slightly turned in this direction, though not always to the extent that Dupuytren states, and the inner malleolus projecting under the skin; most commonly the toes are turned somewhat out, and the heel in. Fractures of the lower ends of the Tibia and Fibula present four distinct varieties. 1st. The fibula may be broken at from two to three inches above the mal- leolus externus, the deltoid ligament being either stretched or torn. 2d. The fibula may be fractured about three inches above the ankle, the tip of the malleolus internus being splintered off as well. This constitutes the form of injury called " Pott's fracture," and is perhaps the most common fracture in this situation. 3d. The fibula may be fractured at about three inches above the ankle, and the lower end of the tibia at the same time be splintered off in an oblique direc- tion from without, downwards and inwards (Fig. 10J.). And, lastly, the internal malleolus may alone be broken off,-the fibula remaining sound, but one of the divisions of the external lateral ligament being torn through. The signs of these fractures vary somewhat according to the bone that is 234 SPECIAL fractures. injured. Fig. 101. When the fibula alone is broken, there is but slight displacement of the foot, but great pain and much swelling, with perhaps indistinct crepitus and irregularity of outline at the seat of fracture. If the tip of the inner malleolus is broken off as well, this may be ascertained by feeling the depres- sion above the detached fragment. In those cases in which the lower end of the tibia is obliquely splintered, as well as the fibula broken, there are not only the ordinary signs of fracture, with eversion of the toes, and a cor- responding turning inwards of the heel, and some rota- tion of the foot outwards, but the malleoli are widely separated, giving an appearance of great increase of breadth to the joint; crepitus is very readily felt, and a depression can be perceived corresponding to the line of fracture. In these cases there is always a great deal of swelling from ecchymosis and inflammatory action, which requires to be subdued by the continuous application of cold be- fore any apparatus can be applied. If there is not much displacement of the foot, the treatment may best be conducted by splints with good foot-pieces, and the starch bandage. If the foot be much twisted, Dupuytren's splint should be applied on the opposite side to that on which the twist of the foot has taken place, the pad being thickly folded at its lower end, and not descending below the ankle. Much stiffness is always felt after union has taken place, the ankle remaining weak and useless for a long time. Compound Fractures of the ankle-joint are very serious injuries, commonly requiring amputation, if associated with dislocation and extensive wound of the soft parts. If, however, the wound be of but moderate extent, clean cut, and the tibial arte- ries uninjured, the fractures should be reduced, a portion of bone being perhaps sawn off in order to accomplish this, and the limb then placed upon a leg-splint with the foot well supported. Fractures of the foot almost invariably result from direct violence, and are usually ac- companied by much bruising, and injury of the soft parts; hence there is usually but little dis- placement, and when the fracture is simple, rest and position alone are necessary. Compound fractures of the foot, attended by much bruising, often require partial removal of the part, or am- putation of the leg. The only special fractures of the foot requiring particular attention, are those of the calcaneum and the neck of the astragalus. The calcaneum may be broken either by direct violence, as when a person jumping from a height alights forcibly on his heel, and thus fractures the bone; or else by the powerful action of the muscles of the calf tearing off a portion of the bone. When the os calcis is broken through at its posterior part, beyond the insertion of the lateral ligaments, the detached fragment will be drawn up by the action of the strong muscles of the calf. But when the fracture occurs across the body of the bone, no displacement can take place, owing to fractures of the ribs. 235 the lateral and interosseous ligaments keeping the posterior fragment in posi- tion, and preventing its being drawn away. In the first form of fracture, the pain, swelling, flattening of the heel, and prominence of the malleoli, indicate the nature of the injury, even though crepitus be wanting. In the second variety, the mobility of the fragment, and its projection posteriorly by the muscles of the calf, point to the existence of the fracture, which is confirmed by the occurrence of crepitus. In the treatment of these injuries, subduing inflammatory action, keeping the part fixed, by means of bandage and gutta-percha splints, with due attention to the relaxation of the muscles, is all that can be done. Union probably occurs by bone in some cases, though very commonly by fibrous tissue. [In fig. 102, the simplest treatment of fracture of the os calcis is represented, the leg being flexed upon the thigh, and the foot extended upon the leg, by means of a slipper, attached by a cord to a band encircling the lower part of the thigh.] Fracture of the ribs and costal cartilages.—These injuries commonly arise from direct violence, the part that is struck being driven in towards the thoracic cavity, and thus broken. In other cases again the fracture occurs by indirect violence, the fore part of the chest being forcibly compressed, so that the rib is bent outwards, and thus snaps. When the injury is the result of direct violence, the pleura, lung, liver, or diaphragm, may be wounded, thus giving rise to the most serious and fatal consequences, such as hemorrhage, emphysema, and inflammation of the parts injured. When it is occasioned by indirect violence, the thoracic organs may be contused and thus injured, although, as the fracture takes place in a direction outwards, they are not under the cir- cumstances liable to be punctured by the fragments. In some rare cases, the ribs have been known to be broken by the violent contraction of the abdominal muscles during parturient efforts. Any one of the ribs may be broken, and frequently several are fractured at the same time. The middle true ribs are those that most frequently give way, being most exposed, and at the same time fixed. The first and second ribs are seldom broken, being protected by the clavicle and shoulder; when fractured, the injury is always a very dangerous one, on account of the importance of the subjacent structures. The lower ribs being less firmly fixed than the others, commonly escape, unless very great and direct violence be inflicted upon them. Any part of a rib may be broken by direct violence; but when the fracture is the result of compression of the chest, it is usually the convexity, or the neigh- borhood of the angle of the rib that gives way. These fractures most commonly occur in elderly people, in whom the elasticity of the thoracic parietes has less- ened as the result of age. Symptoms. — The chief symptom complained of is a sharp pricking and catching pain at the seat of injury, in breathing deeply, or in coughing. In order to avoid this, the inspirations are shallow, and the breathing principally abdominal. On laying the hand over the seat of injury, and desiring the pa- tient to cough, a crepitus may often be felt; and in most cases this is audible on applying the ear to the chest. Occasionally the outline of the rib will be found to be irregular, and in some instances, where several ribs are broken, the whole side of the chest is flattened and depressed. In treating fractured ribs, the surgeon need not concern himself so much about the union of the fracture, as about the prevention of pain to the patient in breathing, and the subsequent occurrence of serious inflammation or other mischief within the chest. Any displacement that may exist usually remedies itself without the neces- sity of the surgeon interfering. If, however, a portion of the rib continues depressed, it had I think better be left so; the suggestions that have been made for elevating these fractures by means of sharp hooks and screw probes, 236 injuries of joints. beino- more likely, than the continuance of the depression, to occasion serioua mischief to the contents of the thorax. In order to prevent undue motion of the broken bone, and consequent irritation produced by its puncturing the pleura or lung, the movements of the injured part of the chest may be restrained by the application of a broad flannel roller, or of a laced napkin round it. Instead of these means, I have for some years past found it more useful to apply a roll of adhesive plaster round the chest. The plaster must be about a foot in width, and should be sufficiently long to make one and a half turns round the body. It should be applied very tightly, and may be left on for ten days or a fortnight, when it may require re-application. It supports the chest more firmly° and evenly than an ordinary bandage, affording the patient great comfort. The prevention of inflammatory action must be attempted by the employ- ment of bleeding, if necessary; but certainly by the adoption of a spare diet and complete rest. Any complication that may occur, such as emphysema, inflammation of the lungs or pleura, must be treated in accordance with the principles that will be laid down in speaking of injuries of the chest generally. It occasionally happens that one or more of the costal cartilages, especially the fifth, sixth, seventh, or eighth, is broken by direct violence. This injury requires the same treatment as a fractured rib; the broken cartilage most com- monly uniting by a bony callus which surrounds the fractured ends. CHAPTER XVI. INJURIES OF JOINTS. Joints are often contused by kicks, falls, or blows, so as to be severely injured, with much pain, and consecutive inflammation of the capsule, synovial mem- brane, or other structures entering into their formation. The treatment should be actively antiphlogistic, with complete rest of the part. In a later stage, an elastic bandage, cold douches, and friction, are useful. In some cases the bursa, situated in the neighborhood of a joint, is seriously bruised, and becomes inflamed in consequence; often giving rise to troublesome suppuration and some sloughing. When this takes place, free incision into the inflamed part, in addition to the ordinary antiphlogistic treatment, will afford speedy and effectual relief to the patient. Sprains.—When a joint is twisted violently, so that its ligaments are either much stretched or partially torn, though there is no displacement of the osseous surfaces, it is said to be sprained. These injuries are exceedingly troublesome, and most frequently occur to the wrist and ankle joints. The pain attending them is very severe, and often of a sickening character, and the sprain is rapidly followed by swelling and inflammation of the joint and investing tissues, often of a very chronic and tedious character. As the inflammation subsides, stiffness and pain in using the part eontinue for a considerable length of time, which, in some cases, give way to a kind of rigidity and wasting of the limb. In others, again, a rheumatic tendency appears to be set up by injuries of this description, and occasionally it happens that in strumous subjects destructive disease of the joint is induced. WOUNDS OF JOINTS. 237 If the sprain is slight, rubbing the part with a stimulating embrocation, and giving the support of a bandage, is all that need be done. But if it be at all severe, more active measures must be had recourse to. The best mode of averting the inflammation, which is the thing to be dreaded in these cases, is to keep the part for several hours in cold water, or well moistened with an evapo- rating lotion, or wet by means of irrigation. Should this not check the inflam- mation, leeches should be freely applied, and when the swelling has somewhat subsided, the joint should be supported with an elastic roller or stocking, a starch bondage, or a leather splint, and be well douched with cold water twice a day, and afterwards rubbed or kneaded with soap liniment, until its usual strength and mobility are restored. This, however, very commonly does not occur in sprains of the knee and ankle for many weeks; a degree of stiffness, combined with inflammation, being left until the stretched and lacerated liga- ments have regained their normal condition. WOUNDS OF JOINTS. A joint is known to be wounded when synovia escapes from the aperture, or when the interior of the articulation is exposed. If there is any doubt as to the wound penetrating the synovial membrane, no means, by probing or other- wise, should be taken to ascertain this, as in this way the very occurrence that is to be dreaded may be induced by the surgeon. The fact of the wound pene- trating the joint will speedily be cleared up by the symptoms that supervene. The severity of the wound of a joint depends chiefly on the size of the articu- lation, but partly on the nature of the wound. When a small joint, as one of the fingers, is opened, the injury may often be recovered from, without destruction of the articulation. When a large joint is opened, even by a small incised or punctured wound, there is great danger lest such extensive local mischief and constitutional disturbance ensue as to lead to the destruction of the articulation, with loss of the patient's life. When the wound is large, lacerated, or contused, with fracture of the articular ends of the bones, one or other of these consequences certainly results. It is especially in grown-up persons that these unfavorable consequences ensue; in children, ex- tensive injuries of large joints may heal favorably, though, if the child be of a strumous habit of body, destructive action is apt to be set up. The source of danger in a wounded joint is the inflammation set up in the articulation (traumatic arthritis). A few hours after the infliction of the injury the joint swells, becomes hot, painful, and throbs. The pain increases, becoming tensive and excessively severe. If the aperture be large, synovia freely escapes, which soon becomes mixed with pus. If it be small, but little more than a puncture, the joint swells and fills with purulent fluid, which will either escape through the original wound or find an outlet for itself through a new situation. There are startings in the limb, with excessive pain in any attempt at moving it. The constitutional disturbance becomes very severe, the patient being occa- sionally carried off by the violence of the irritative fever. In other cases symptoms of purulent absorption come on, and death results from pyemia. If the patient survive this period of acute action, abscesses will form around and above the articulation, the discharge from which, as well as from the joint, induces irritative fever and hectic. Should this danger be passed through, and the patient survive, it will be with a partially anchylosed limb, the utility of which is greatly impaired. The severity of the symptoms in the wound of a large joint is evidently dependent on the extent and depth of the synovial membrane which suppurates, and to the pus thus formed being pent up in the midst of tense and unyielding ti«sues, from which it has not a free exit. It is the admission of air into the joint that occasions the suppuration, for we find that in the most extensive sub- 238 INJURIES OF JOINTS. cutaneous wounds and lacerations of joints, as occur in dislocations and fractures, suppuration scarcely ever takes place. The presence also of the air appears to exercise an injurious influence upon the pus that is collected in the depths of the joint, causing it to become putrescent and acrid, and thus increasing the local irritation greatly. It is also this retention of acrid and putrescent pus, in contact with a large inflamed surface, that gives rise to ataxic fever and pyemia, that so frequently prove fatal in these injuries. Traumatic arthritis differs from the destructive and disorganizing idiopathic inflammations of joints in this: that when the inflammation occurs as the result of a wound, the synovial membrane is the part primarily affected; if the carti- lages become involved, they are so secondarily; the articular ends of the bones not participating in the morbid action. When a joint is the seat of disorganizing inflammation of an idiopathic character, the mischief usually commences in the osseous articular ends, or in the cartilage, the synovial membrane being often the last affected. In the traumatic form, the disease may be said to radiate from the centre of the joint; in the idiopathic, from the circumference. In recent cases of traumatic arthritis we find the synovial membrane swollen, infiltrated, gelatinous-looking, and of a crimson color; the contiguous or sub- jacent portions of cartilage are softened and partially eroded. Under the microscope, a disruption of the cartilage cells may be observed, and the inter- vening substance is granular; these changes gradually cease in deeper sections of the cartilage, which will be found to present a healthy appearance. In the more advanced stages of the disease, when the joint has been suppurating per- haps for months, it will be found that the synovial membrane is deeply vascular in places, in other parts pulpy and infiltrated with, or replaced by grayish or yellowish plastic matter. The cartilages are eroded in patches, exposing the rough and injected surface of the articular extremity of the bone; where not eroded they are pulpy and disorganized. Occasionally partial but unsuccessful attempts at bony union will have been set up between the opposed exposed osseous surfaces. In the treatment of wounded joints, the first point to be determined must be whether amputation should be performed, or an attempt made to save the injured limb. If the joint be small, there can be no doubt that we may attempt, and shall usually succeed in saving it. But if it be one of the larger articulations, the line of practice must be determined by the extent of the injury to the soft parts, and the constitution of the patient. If the wound be but small, and is clean cut, no surgeon would be justified in having recourse to immediate ampu- tation, even though it be the knee that is injured. But if the joint is exten- sively laid open, with much contusion and laceration, perhaps dislocation, or fracture and splintering of the bones, the case is different. Under these unfa- vorable circumstances, however, in the upper extremity, and even in the ankle, the limb may not unfrequently be saved. If the bones be comminuted, the removal of splinters and partial resection of the articular ends, may advantage- ously be practised in many cases, more particularly if the patient's constitution be young and sound, and the soft parts not too extensively damaged. But if these be largely lacerated and widely contused, and the patient aged or broken in health, amputation is imperatively called for. This is more especially the case, when the knee is the articulation injured; extensive lacerations of this joint, more particularly complicated with dislocation or comminution of the bones, being cases for early amputation. If it be determined to make an attempt at saving the limb, the principal point is, if possible, to close the wound by the first intention, and thus to prevent the occurrence of suppuration. If it be a puncture, or clean cut wound, this may occasionally be done by bringing its edges together and placing a piece of lint soaked in collodion upon it, or a strip of plaster washed over with resin varnish, the inflammatory action being subdued by continuous irrigation with cold water: DISLOCATIONS. 239 no poulticing or warm fomentations should ever be allowed during this stage. Union may take place under this dressing, but in the majority of cases the in- flammation that is set up in the joint, causes so abundant a secretion of synovia, that it becomes loosened by the tension and outward pressure of the accumulated fluid which escapes from under it. If suppuration have come on, free incisions, as recommended by Mr. Gay, should be made into the joint so as to procure an early outlet for the pus; the part must be well poulticed, and an attempt made at procuring anchylosis by the granulation and cohesion, through fibrous tissue, of the articular surfaces. By making free and early incisions into the joint after suppuration has once been sat up, the dangers resulting from decomposition of the pus and its absorp- tion into the system are in a great measure lessened, and the constitutional irri- tation produced by the tension of the parts at once removed. The joint itself is not put into a worse condition by being more freely opened, for when one suppuration has been set up in it, even to a limited extent, destruction of its tissues must ensue; and the most favorable termination that can be expected is the production of anchylosis. At the same time constitutional treatment must be employed, with the view of lessening febrile action and removing irritation; the administration of antimonials, with calomel and opium, being especially ser- viceable; but free purging and all other sources of irritation should be avoided. If the case proceed favorably the discharge will gradually lessen, and the constitutional disturbance subside. The joint must then be placed in such a position, that when anchylosis results, the limb may be most serviceable to the patient. If, however, as very frequently happens when the larger joints are wounded, the suppuration within the articulation, and the abscesses that form outside it, reduce the patient to a hectic state, secondary amputation speedily becomes inevitable. When the wound in the joint is too extensive for union by the first intention to be effected, and yet it be thought proper to make an effort to save the limb, the continued application of ice or of cold irrigation, and active antiphlogistic treatment, must be had recourse to, and free and early incisions to relieve ten- sion and let out matter, so as to lessen the intensity of the suppurative inflam- mation that will be set up. In the great majority of these cases, however, where the larger joints, of the lower extremity especially, are implicated, ampu- tation will eventually be required; the instances of recovery under these circum- stances being altogether exceptional, the patient indeed not unfrequently sinking during the attempt at saving the limb. DISLOCATIONS. By a dislocation is meant the more or less complete displacement of the bony structures of a joint. In the orbicular joints, as the hip and shoulder, the osseous structures may be completely separated from one another, the disloca- tion then being complete. In the hinge joints, as the elbow and knee, the osseous surfaces commonly remain partially in contact, though displaced from their nor- mal relations to one another; here the dislocation is incomplete. In most dislo- cations the integuments covering the displaced bones are put greatly on the stretch, but in some_ they are ruptured, and then the dislocation is compound. Besides these varieties, surgeons recognise spontaneous dislocations, in which the displacement does not occur from external violence. In other cases again, the dislocation arises from congenital malformation of the joint, in consequence of which the bones cannot remain in proper apposition. Dislocations are predisposed to by various conditions, amongst which the arrangement of the joint appears to exercise most influence; orbicular joints being more liable to dislocation than any of the other articulations, whilst in 240 INJURIES OF JOINTS. some of the synchondroses they never occur. Malgaigne finds, that of 491 cases of dislocation, 321 occurred in the shoulder, 34 in the hip, 33 in the clavicle, 26 in the elbow, 20 in the foot, besides others in the thumb, wrist, and jaw. Dislocations are seldom met with in children, in whom fractures of the epi- physes more readily occur. Travers, however, has seen the hip dislocated in a boy five years of age. In old people the bones are so brittle, and the ligaments so tough, that violence causes fracture rather than dislocation. Hence it is principally in young and middle-aged subjects that dislocations are met with. They are necessarily more common in men than in women, from the nature of their respective occupations. It is well known that it is rather owing to the continuous tension of the muscles, than to any arrangement of their osseous and ligamentous structures, that the articular ends of the bones of the extremities are kept in their proper positions, and that considerable external violence may be applied to a limb without dislocating it. If, however, the muscles be taken by surprise, or if they have been weakened by previous injury of any kind, the joint becomes predisposed to dislocation, and may be displaced under the influence of very slight causes. In this way the same joint may be repeatedly dislocated. Thus I have seen a man whose humerus had been dislocated between 40 and 50 times, owing to a weakened state of the deltoid. The direct causes of dislocation are external violence and muscular action. The external violence may act either directly upon a joint, forcing or twisting the articular ends asunder, as happens when the foot is displaced by a twist of the ankle, or when the thumb is dislocated backwards by a blow. But more commonly the force acts at a distance from the joint that is displaced, and the head of the bone is thrown out of its socket by " the lever-like movement of the shaft," as happens when the head of the humerus is dislocated by a fall on the hand. Muscular action alone may cause the dislocation of a bone, even though the part be previously in a sound state. Thus, the lower jaw has been dislocated by excessive gaping, and the humerus, by making a violent muscular effort. If the joint have^ already been weakened by previous injury or disease, muscular action is especially^ apt to occasion its displacement. The congenital disloca- tions, in all probability, arise from irregulaf muscular contractions in the foetus by which the bones are displaced, and the normal development of the joint interfered with. In dislocations of the orbicular joints, after the head of the bone has been thrown out of its articular cavity, it is often still further displaced by the contraction of the muscles, which continues until they have shortened themselves to their full extent, or until the dislocated bone comes in contact with some osseous prominence that prevents its further retraction. The existence of a dislocation is rendered evident by the change in the shape of the joint, and in the altered relation of the osseous prominences to one another; by the articular end of the displaced bone being felt in a new posi- tion, and by an alteration in the length of the limb, and in the direction of its axis. Besides this, there is after a time, if not immediately on the occurrence of the accident, impaired motion of, and pain in and around, the injured articulation. The effects of dislocation on the structure of a joint are always of a serious character. The bones that enter into the formation of the articulation are not unfrequently fractured as well as displaced, more particularly in hinge joints; the cartilages may be injured, and the ligaments are always much stretched and more or less torn, the capsule of the joint suffering especially. In many cases the muscles and tendons in the immediate neighborhood are lacerated as well as displaced, and the vessels and nerves compressed. The skin is commonly stretched, and sometimes ruptured, when the dislocation becomes compound. REDUCTION OF DISLOCATIONS. 241 If the dislocation be a simple one, and if reduction be speedily effected, these injuries are soon repaired; and although a good deal of stiffness may continue about the joint, its functions are not usually permanently interfered witk If the dislocation be left unreduced, important changes take place within and around the joint. Its cavity becomes filled up by a kind of fibrinous material, almost cartilaginous in structure. The ligaments are shortened and^wasted, and a false joint forms around the articular end of the bone in its new situation. In some cases the bone upon which the dislocated head rests becomes depressed into a shallow cup-shaped cavity, so as to receive it. In others the depression is formed by the elevation of a rim of callus upon the subjacent bone, and in both instances the cellular tissue in the neighborhood becomes consolidated into a capsule of a fibroid character, surrounding and fixing the bone in its new situ- ation, and usually admitting of but a limited degree of motion. The soft structures that have been lacerated at the time of the dislocation become matted together by plastic material, the muscles shorten, atrophy, and at last undergo fatty degeneration from disuse; the neighboring vessels and nerves may become attached to the new joint, or their sheaths become incorporated with the altered structures in contact with them. In the treatment of dislocations, the first and principal indication consists in replacing the bone in its normal situation as speedily as possible. In doing this, the surgeon has two great difficulties to overcome: 1st, the contraction of the muscles of the part; and, 2nd, the anatomical structure of the joint. The great obstacle to reduction is, the tonic contraction of the muscles in- serted into or below the displaced bones; and in the reduction of the disloca- tion the surgeon's efforts are chiefly directed to overcome this contraction. The longer the dislocation is left unreduced the more powerful does this become, being less at the moment of the accident, and immediately afterwards, than at any subsequent period. Hence reduction should be attempted as soon as pos- sible after the occurrence of the accident, and if the patient be seen at once, the bone may sometimes be replaced without much difficulty by the unaided efforts of the surgeon. Thus Liston reduced a dislocated hip by his own efforts immediately after the accident occurred. If a few hours have elapsed, the muscular tonicity becomes so great that special means must be adopted in order to diminish it; and if some weeks or months have been allowed to pass by, the dislocation may have become irreducible, partly owing to permanent contraction of the muscles which have been shortened by the approximation of their attachments, and which it is impossible to overcome, but chiefly, by the cohesion of the surrounding tissues, and the formation of adhesions about the head of the bone. In the reduction of a recent dislocation, advantage may sometimes be taken of the occurrence of faintness, or of the patient's attention being distracted to other matters, in order to effect the return, the muscles being then taken by surprise, and the bone readily slipping into its place. Such measures as these, however, cannot be depended upon, and muscular relaxation should be induced by the administration of chloroform or ether. By the employment of these valuable agents, the muscles of the strongest man may be rendered perfectly flaccid and powerless in a few minutes, so as to oppose no action whatever to the reduction of the dislocation, which has thus been wonderfully simplified and facilitated. In no department indeed of practical surgery has the administra- tion of anaesthetic agents been attended by more advantageous results than in this. Mechanical contrivances are much less frequently had recourse to for the reduction of dislocation now than formerly. It is, however, occasionally neces- sary to employ apparatus calculated to fix the articular surface from which the bone has escaped, and to draw down the displaced bone to such an extent that it may be replaced on the surface on which it should be lodged. If the patient 16 242 INJURIES OF JOINTS. Fig. 103. have not been anaesthetized, it will be found that so soon as the bone is well brought down by the extending force so as to get opposite its articulation, being disentangled from osseous points upon which it may have hitched, it will be drawn at once into its proper position by the action of its own muscles, with a sudden and distinct snap; the muscles of the part being the most efficient agents in the reduction, so soon as the bone is placed in a position for them to act upon it. When, however, the patient has been placed under the influence of chloroform, the muscular system being thoroughly relaxed, the bone will not slip into its place with a snap or'sudden jerk, but is reduced more quietly, and rather by the efforts of the surgeon than by any sudden contraction of its own muscles. It is important to note these differences in the mode of reduction, lest the surgeon, expecting to hear the snap or feel the jerk when chloroform has been fully administered, and, not doing so, should imagine the bone not to be reduced, and continue an improper degree of extension. The purely mechanical means for the reduction of dislocation are sufficiently simple: the patient's body, and the articular cavity into which the luxated bone is to be replaced, are fixed by a split sheet, a jack-towel, a padded belt, or some such contrivance, by which counter-extension is practised. In some cases the hands of an assistant, or of the surgeon himself, or the pressure of his knee or heel constitute the best counter-extending means. Extension may now be made either by the surgeon grasping the limb to be reduced and drawing it downwards, or else by means of a bandage or jack- towel fixed upon the part, with the clove-hitch knot applied in the way represented in the an- nexed cut (fig. 103). If more force be required, the multiplying pulleys (fig. 125), or the dislo- cation tourniquet invented by Mr. Bloxam (fig. 126), may be used, by which any amount of extending force that may be required can readily be set up and maintained. The "adjuster" in- vented by Dr. Jarvis is a useful and powerful instrument for the same purpose. These con- trivances, however, are much less frequently required now than formerly, owing to surgeons taking advantage of the paralyzing effects of chloroform upon the muscular system, and con- sequently not requiring so much force to over- come their contractions. When any powerful extending force is applied, the skin of the part should always be protected from being chafed, by a few turns of a wet roller. The extension must be made slowly and gradually, without any jerking, equality of motion as well as force being attended to. In this way the contraction of the muscles is gradually overcome, whereas sudden and forcible extension might excite them to react against it. The traction is most advantageously made in the axis that the limb has acquired in its new position, without reference to its normal direction or to the situation of the joint. In this way the head of the bone is replaced by being made to pass along the same tract that it has torn for itself in being dislocated, and thus is replaced without the infliction of any additional violence to the tissues around the joint. The question as to whether the extending force should be applied to the bone that is actually displaced, or to the further end of the limb, has been much discussed, and appears to have received more attention than it deserves. It is true that, by applying the extending force to the displaced bone itself, the REDUCTION OF DISLOCATIONS. 243 surgeon has greater command over its movements, with less chance of injury to the intervening bones; whilst, by applying the extending force to the lower part of the extremity, he has the advantage of a longer lever for the reduction of the head of the bone. This lever, however, it must be remembered, is in many cases a broken one, and cannot be made to act if the bone has to be replaced in the direction of the flexion of the joints that enter into its compo- sition. For this reason, we find that some dislocations are best reduced by applying traction to the bone itself that is displaced, as in luxations of the femur and of the bone of the fore-arm; whilst, in other cases, as in the dislo- cations of the humerus, most advantage is gained by applying the extending force to the end of the limb. But I look upon these points as of comparatively little consequence, believ- ing that when the patient is not anaesthetized, the muscles of the limb themselves effect the reduction without the necessity of the surgeon employing any very powerful lever-like action of the bone; and that when the patient is paralyzed by chloroform, the bone is in most cases readily replaced by the simple move- ments impressed directly upon it, or even upon its articular end, by the hands of the surgeon. In reducing a dislocation, it is of especial importance to attend to the rela- tion of the osseous points in the neighborhood of the joint, and to disentangle the displaced bone from any of these upon which it may be lodged. This is especially the case in such hinge-joints as the jaw and elbow, in which the arrangement of the articulation is somewhat complicated. After the dislocation has been reduced, the bone must be retained in position' by proper splints and bandages, if necessary; the joint being kept quiet for two or three weeks, according to its size, so as to allow of proper union taking place in the capsule and neighboring structures. Any consecutive inflammation may often be prevented by the continuous application of cold; and, if set up, must be treated by local antiphlogistic means. In dislocations of old standing, reduction is opposed not only by the powerful contraction of shortened muscles, and by a kind of rigid atrophy of the neigh- boring structures, but also by the existence of adhesions between the displaced bone and surrounding parts. If the dislocation have existed for several months, these obstacles will in general be sufficiently powerful to render it impossible to effect the reduction at all, or without the employment of such force as to occasion dangerous laceration of the tissues about the displaced bone, and serious inflammation of them; as happened in the cases related by Dr. Gibson, in which rupture of the axillary artery followed attempts at reducing old dislo- cations of the shoulder. If it be determined to attempt the reduction, the pulleys must be used, the patient being put under chloroform; but every pre- caution must be taken not to allow the traction to be carried to too great extent, lest sudden laceration of the parts occur. The latest period at which reduction should be attempted, varies much ac- cording to the nature of the dislocation. It may be successfully practised at a much later period in luxations of the orbicular than of the hinge joints; and it is especially in the shoulder that these late attempts may be advantageously undertaken. According to Sir A. Cooper, however, the latest period at which reduction even in this articulation can generally be successfully effected, does not exceed three months and eight weeks for the hip; but within this time it may often be safely accomplished, Thus, Dupuytren reduced twenty-three cases of dislocated shoulder between the fifteenth and eighty-second day after the accident; and Breschet reduced the hip on the seventy-eighth day. At a considerably later period, however, than this, the luxated bone has been put into place. Thus Smith, of the United States, reduced one dislocation of the shoulder at the seventh month, and another at ten and a half months. In the reduction of some of these old-standing dislocations, it has been proposed to 244 INJURIES OF JOINTS. divide by the subcutaneous section those muscles which appear to offer the greatest obstacle to the return of the bone. In this way Dieffenbach has suc- ceeded in reducing a dislocation of the humerus two years after its occurrence. In some cases, however, as I have more than once witnessed, this plan does not succeed, owing evidently to the existence of contractions in, and adhesions between, other tissues than the muscular, and to the changes that have taken place in the articular surfaces, preventing the head of the bone being replaced or retained in its new position. Compound dislocations are amongst the most serious injuries to which the limbs can be subjected. For not only is there such extensive laceration of the soft parts that cover and enter into the formation of the joint, as to give rise to the most severe forms of traumatic arthritis, but the bones are often fractured, and the main vessels of the limb perhaps greatly stretched or torn. The treatment of a compound dislocation must be conducted on the same principles that guide the surgeon in the management of a wounded joint; — obtaining union if possible by the first intention, subduing inflammatory action, and letting out matter as it forms. Owing to the rupture of the ligaments and of the muscular attachments, there is usually no difficulty in the reduction, the bones being readily replaced; but the danger consists in the destructive inflam- matory action that will be set up in the joint and limb, from the extensive injury inflicted upon them. This varies greatly, according to the size and situation of the joint, and the state of the soft parts. If it be small, as one of the phalangeal articulations, the dislocation may be reduced, and the parts .covered with cold lint. If it be one of the larger joints, the line of practice will vary according to other circumstances than the mere dislocation. Thus, if it be in the upper extremity, the patient being healthy, and the soft parts not very extensively contused or torn, the bones may be replaced, cold irrigation assiduously applied, and antiphlogistic treatment pursued. If there be fracture conjoined with the dislocation, resection should be attempted, as was success- fully practised by Hey in several cases of injury of the elbow of this descrip- tion ; but if the soft parts be greatly injured as well, and especially if the blood- vessels and nerves of the limb have suffered, amputation must be performed. In the lower extremity, amputation is more frequently necessary; in the knee, almost invariably so. Sir A. Cooper states that he knows no accident that more imperatively demands amputation than compound dislocation of this joint. Yet there are exceptions to this rule; thus, Mr. White had a case of compound dislocation of the knee-joint in a boy, nine years of age, at the Westminster Hospital, in which he saved the limb by sawing off the condyles of the femur and reducing the bone. In the compound dislocations of the ankle and the astragalus, an attempt should generally be made to save the limb, in the way that will be more specially pointed out when we come to treat of these injuries. After recovery from compound dislocations, the joint will remain permanently anchylosed; hence attention to position during the treatment is essentially required In many cases, however, very good motion is ultimately obtained, though the stiffness may continue for some length of time. The complication of fracture of the shaft of°one of the long bones with dis- location of its head increases considerably the difficulty of reduction Under these circumstances, it has been recommended to consolidate the fracture first, and then to attempt the reduction. But to do this is only to defer and increase the difficulties. At least seven or eight weeks would elapse before the fracture were sufficiently firmly united to bear the requisite traction to reduce so old a dislocation, and then there would be great chance of rupture of the callus, and certainly extreme difficulty in the reduction. It therefore appears to me much safer, under all circumstances, to reduce the dislocation at once, and afterwards to treat the fracture in the ordinary way. In reducing a dislocation complicated with fracture of the shaft of the displaced bone, the fracture must first be put SPONTANEOUS DISLOCATIONS. 245 up very firmly indeed, with wooden splints completely encasing the limb. The patient must then be put fully under the influence of chloroform, which is of the most essential service in these cases, and when the muscles are completely relaxed, extension and counter-extension being made in the usual way, the reduction may be effected. The extending means should always be applied upon the splints, so that there may be no dragging upon the fracture. In this way I reduced last winter, without any difficulty, a dislocation of the head of the humerus into the axilla, complicated with comminuted fracture of the shaft of the bone, in a remarkably muscular man to whom I was called by Mr. Byam, and about the same time I had a case of dislocated elbow, with fracture of the shaft of the humerus, under my care at the Hospital, that was reduced with ease in the same way. After the bone has been reduced the fracture can be treated without difficulty. When a simple fracture extends into the articular end of the bone, as in some dislocations about the elbow and ankle, there is no material increase in the danger of the case or in the difficulty of its management. In compound dislocation with fracture of the articular ends, removal of splinters, partial resection or amputation will be required, according to the seat and extent of injury. Spontaneous dislocations may occur either suddenly or gradually, according to the nature of the cause that gives rise to them. In many cases they result from the destruction of the joint by old disease; the ligaments and cartilages being destroyed by suppuration, the head of the bone becomes carious and absorbed, and the articular surfaces are displaced by ordinary muscular action. This we commonly see in old cases of hip disease. There, is, however, another and more rare form of spontaneous dislocation to which the hip and shoulder are liable, and which has been especially studied by Mr. Stanley. In these dislocations the head of the bone slips out of the articulation without any very marked sign of disease about the joint, and certainly without any previous destruction of it. In these cases there is either a paralytic condition of the capsular muscles, as has been observed several times in the shoulder, the deltoid having become paralyzed and thus allowed the bone to slip out of place; or, as has been noticed in the hip, obscure rheumatic or neuralgic pains have for some time been seated in the joint. The dislocation may not be confined to one joint, but may affect several. Thus some time ago there was a case in University College Hospital, in which both shoulders and hips were dislocated spontaneously. In many cases it occurs suddenly, and often without any pain to the patient, the deformity of the limb attracting attention to the accident, though in others it has been preceded by rheumatic affection of the joint. The treatment of these cases is not very satisfactory. Reduction in many cannot be accomplished, but in others it may be effected readily enough; though the bone cannot be fixed in the joint, out of which it slips again. In a case of spontaneous dislocation of the hip, without any apparent disease of the joint occurring, in a young woman who was placed under my care by Mr. Ashton, I readily effected reduction by the pulleys, three weeks after the occurrence of the displacement. The limb was then fixed with the long splint, and maintained at a proper length for two or three weeks; when, in consequence of a severe bronchitic attack, it became necessary to remove the apparatus, and the displacement speedily returned. Whilst convalescent from this attack she fell and fractured the displaced femur in its upper third, thus rendering it impossible to replace the bone again. In another case of spontaneous dislocation of the knee, occurring in the same painless manner, the joint could not be replaced, and permanent deformity was left. After reduction in similar cases, a splint or starched bandage should be worn for a considerable length of time, so as to give a chance for the ligaments of the joint to recover themselves. If there be a rheumatic tendency, that should be removed by 246 SPECIAL DISLOCATIONS. suitable treatment, and if there be a paralytic condition of the muscles, elec- tricity, the endermic application of strychnine and cold douches with friction, may be advantageously employed. Congenital dislocations are occasionally met with in the hip, shoulder, wrist, and jaw, and have of late years attracted the attention of surgeons through the labors of Gu6rin, Smith, Chelius, Robert, and others. These dislocations are closely allied in cause and nature with other congenital deformities of the limbs, such as club-foot, &c. In them there is usually found imperfect development of some portions of the osseous articular apparatus. Whether this is so origi- nally, thus causing the displacement of the bones, or consecutive upon disuse, occasioned by spasmodic action of the one set of muscles or paralysis of an- other, dependent on some irritation in the nervous centres, is scarcely worth in- quiring here. In some cases it would appear as if faulty position of the foetus in utero, or undue violence during birth, may have occasioned the displacement. These dislocations are probably incurable, as there is always congenital defect of structure in the articular ends of the bones. CHAPTER XVII. SPECIAL DISLOCATIONS. Dislocations of the lower jaw are of rare occurrence, and when met with are frequently occasioned by spasmodic action of its depressor muscles, — opening the mouth too widely, as in fits of laughing, of gaping, or in attempting to take too large a bite. Occasionally this accident has resulted from blows'or kicks upon the chin, or from the violent strain upon the part in tooth-drawing. The mechanism of the dislocation is simple; when the mouth is opened the inter-articular fibro-cartilage with the condyle glides forwards on to the emi- nentia articularis. If this movement be continued too far, and the external pterygoid musclecontracts forcibly at the same time, the condyle slips forward into the zygomatic fossa, the coronoid process hitching against the malar bone, the axis of the ramus being directed obliquely backwards, and the dislocation being thus complete. In this way both condyles may be displaced, or only one. The signs^ of this dislocation are evident from the nature of the accident. The mouth is widely opened and cannot be closed; deglutition and speech are impaired, the labial consonants not being pronounced; there is dribbling of saliva over the lower lip; the chin is lengthened, and the lower line of Teeth advanced before those of the upper jaw; the cheeks are flattened, and there is a depression in front of the meatus externus. There is also an oblong promi- nence in the temporal fossa between the eye and the ear. If the dislocation is left unreduced, the patient slowly regains some power of movement over the jaw; he gradually approximates the lips, and, after a length of time, may even be enabled to bring the lines of teeth into apposition. When one condyle only is dislocated, the axis of the lower jaw is directed towards the opposite side to that on which the displacement exists, and the general signs are the same, but in a less marked degree, as those that are met with when both sides are dislocated. The hollow before the meatus on the injured side is, however, well marked, and serves to point out the seat and °aiUr? °d w displacement, the diagnosis of which is not always readily made; indeed, R. W. Smith states that he has seen attempts at reduction applied to the uninjured side. dislocations of the CLAVICLE. 247 Sir A. Cooper has described a subluxation of the jaw, which is most fre- quently met with in young and delicate women, in which the head of the bone appears to slip before the interarticular cartilage, so as to prevent the mouth being closed. Most commonly the natural efforts of the part are sufficient to return the head of the bone into the glenoid cavity with a loud snap, or a cracking noise. The reduction of a dislocated jaw is easily effected, it being only necessary to push the angle of the bone downwards and backwards, so as to disentangle the coronoid process from under the zygomatic arch, at the same time that the chin is raised by the surgeon's fingers, in order that the temporal and pterygoid muscles may draw the head of the bone into its proper position. The reduction is best effected by the surgeon standing before the patient and applying his thumbs, well protected with a thick napkin, to the molar teeth on either side, and thus depressing the angle of the jaw forcibly, at the same time that he raises the chin by means of his fingers spread out and placed underneath it. The bone is then returned into its place with so forcible a snap, that, unless care be taken, or the thumbs be well covered up, they may be severely bitten. When only one condyle is luxated, the efforts at reduction should be applied to the injured side only. In the cases of subluxation, Sir A. Cooper recommends a tonic plan of constitutional treatment, such as iron, valerian, and shower- baths ; to this I have found the application of a series of blisters over the arti- culation a useful addition. After the reduction the four-tailed bandage should be applied, as in cases of fracture of the jaw, and for several days the patient must not be allowed to talk, or to eat. any solid food, lest the displacement return, which it always has a great tendency to do. Very old dislocations of this bone may in this way be reduced. Thus Stromeyer replaced one at the end of twenty-five, and Donovan one at the end of ninety days. The congenital dislocation of the condyle of the lower jaw is a remarkable and rare condition, for an acquaintance with which we are chiefly indebted to Mr. Smith. In this condition there is a singular distortion of countenance. The osseous and muscular structures on the dislocated side are atrophied, the teeth of the upper jaw projected beyond those of the lower, contrary to what occurs in the accidental dislocations; the mouth can be closed, speech is perfect, and there is no dribbling of saliva. Congenital dislocation of both condyles has not yet been observed. Dislocations of the Clavicle are rarely met with in comparison to the frequency of fractures of this bone, owing doubtless to the short and firm liga- ments by which it is attached to the sternum and acromion, and to its usually receiving any force that is applied to it in a line that corresponds to its axis, thus causing it to be rather bent and broken than luxated. Either the sternal or the acromial end of the clavicle may be dislocated, and the simultaneous displacement of both has even been observed. The sternal end of the clavicle may be luxated in a direction forwards, back- wards, or upwards, being thrown before, behind, or above the sternum. In the dislocation forwards, the end of the bone can be felt in its new posi- tion, the point of the shoulder is approximated to the mesial line, and the depression above and below the clavicle are strongly defined. It is occasioned by blows upon the shoulder, by bending this part forcibly backwards, or by vio- lence applied to the elbow whilst the arm is raised from the side. This dislocation, which is amongst the most frequent to which the clavicle is subject, may readily be reduced by pushing the shoulder outwards and bending it backwards. The principal difficulty in the treatment consists in preventing the return of the displacement, owing to the shallowness of the articular surface upon which the clavicle lodges. With this view a pad and figure of 8 bandage must be firmly applied upon the displaced end of the bone. 248 SPECIAL DISLOCATIONS. The dislocation upwards is of extremely rare occurrence. The signs in the two recorded cases were so evident as not to lead to any difficulty in the diagnosis of the accident, the projection of the sternal end of the clavicle in its new situation being subcutaneous, and at once cognizable to the touch. In the treatment, a bandage and pad, with elevation of the elbow, brought the bone into good position. The dislocation backioards is not of common occurrence, though, according to Nelaton, there are at least ten or a dozen cases on record. This luxation appears generally to have resulted from the point of the shoulder having been driven upwards, or by the hand being violently drawn forwards. It has also been observed to result from the direct pressure of the clavicle backwards, as by the kick of a horse, and has resulted as a secondary consequence of curvature of the spine. The signs are those that usually attend a dislocated clavicle, shortening of the shouider, and deformity about the upper part of the sternum; but, besides these, a special train of symptoms is occasioned, by the pressure of the displaced bone upon the trachea, oesophagus, and vessels of the neck; in consequence of which, so much congestion of the head, giving rise even to a semicomatose state with difficulty in breathing and swallowing, may result, as to require the removal of the end of the bone, as happened in a case related by Sir A. Cooper, in which the surgeon was obliged to saw off the dislocated end. In some cases the end of the bone is thrown upwards as well as backwards; in others it takes rather a downward direction. In the treatment of this dislocation, it is easy to effect the reduction of the bone by making a fulcrum of the fist in the axilla, and then bringing the elbow well to the side, at the same time that an assistant puts his knee between the patient's shoulders and bends them back; but it is difficult to retain it in proper position. With this view, the figure of 8 bandage tightly applied to the points of the shoulders, and crossed over a large pad placed in the middle of the back, will give the most efficient support to the part, the elbow being at the same time well fixed to the side and drawn back. The dislocations of the outer end of the clavicle are more commonly met with than those just described. The most frequent accident of this description is that in which the bone is thrown upon the upper surface of. the acromion or upon the anterior part of the spine of the scapula. In several cases of this accident which have of late years presented themselves at University College Hospital, there has been no difficulty whatever in the diagnosis; the prominence formed by the displaced bone, the narrowing of the distance from the mesial line to the point of the shoulder, the facility of the reduction of the dislocation, and the tension of the clavicular portion of the trapezius muscle, indicate the nature of the accident. The treatment may in general be successfully con- ducted on the same principles as those on which a fractured clavicle is managed. In some cases, however, the dislocation has a tendency to return. Under these circumstances, M. Laugier has found that Petit's tourniquet strapped from the shoulder to the elbow, and properly tightened, keeps the bone in good position. The outer end of the clavicle has been dislocated under the acromion by the application of direct violence to the end of the bone. This form of displace- ment is so rare that Nelaton states that there are only three cases on record; several instances have, however, of late been mentioned in the journals. The diagnosis must be easy, simple digital examination pointing out the nature of the accident, and the treatment must be conducted in the same way as that of fractured clavicle. The acromial end of the clavicle has been known to be displaced underneath the coracoid process. Here also simple examination and the clavicular bandage suffice for diagnosis and treatment. The only instance of simultaneous disloca- tion of both ends of the clavicle that I am acquainted with, has been reported by Richerand. DISLOCATIONS OF THE SHOULDER. 249 Dislocations of the shoulder occur far more frequently than those of any other joint. Their pathology and treatment have been so clearly elucidated by Sir A. Cooper, that there is little left for subsequent writers but to follow the descriptions given by that great-surgeon; though several of the modern French surgeons, especially Velpeau, Malgaigne, and Goyrand, have thrown some new light on the subject. The reason of the frequency of these dislocations is to be found in the shallowness of the glenoid cavity, the large size and rounded shape of the head of the humerus, and the weakness of the ligaments; but, above all, in the extent and force of the movements to which the joint is sub- jected. These displacements indeed would be much more frequent than they even are, were is not for the protection afforded to the joint by the osseous and ligamentous arch formed by the coracoid process and acromion with their liga- ments, the great strength and close connection of the capsular muscles with the joint, and the support given by the tension of the long head of the biceps over its weakest part; but the principal obstacle to dislocation is the mobility of the scapula enabling all movements communicated to the hand and arm to react upon that bone. The shoulder joint is susceptible of four dislocations. Of these, according to Sir A. Cooper, three are complete, and the fourth partial. I think, however, that on examination, it will be found that the so-called partial dislocation is in reality a complete one. The directions in which the head of the bone is thrown are downwards and slightly inwards under the glenoid cavity (fig. 104); for- Fig. 104. Fig. 105. Fig. 106. Fig. 107. wards and inwards beneath the clavicle (fig. 105); backwards and dowmcards under the spine of the scapula (fig. 107); and inwards and slightly downwards beneath the coracoid process (fig. 106). Thus three dislocations are more or less inwards, only one being backwards or outwards. In the dislocation downwards, or the subglenoid (fig. 104), the head of the bone lies in the axilla, resting against the inferior costa of the scapula below the glenoid cavity, and lodged between the subscapular muscle and the long portion of the triceps. This dislocation is the most frequent of all, and is an accident of extremely common occurrence. In it the axillary artery and plexus of nerves are compressed and stretched by the dislocated head of the bone; the tendon of the subscapular muscle is commonly torn near to its insertion to the lesser tubercle of the humerus, and the capsular ligament largely lacerated. The supra-spinatus muscle may also be torn through, or a portion of the great tubercle of the humerus detached, and the rest of the capsular muscles put greatly on the stretch. In the dislocation forwards, or the subclavicular (fig. 105), the head of the bone is thrown on the inner side of the coracoid process, lying upon the second and third ribs under the pectoral muscles, and immediately below the 250 special dislocations. Fig. 108. clavicle (fig. 108). In a case recorded by Mr. Curling, the infra-spinatus and subscapularis muscles were torn away from the tubercles of the hume- rus, and the teres minor partially lacerated, the capsule being completely separated from the neck of the bone, which pressed forcibly upon the axillary vessels and nerves. In two cases which I have had an opportunity of examining, the great tubercle was torn away from the head of the bone with much laceration of the capsule and extensive extravasation. In the dislocation backwards or the subspinous (fig. 107), the head of the humerus lies behind the glenoid cavity, and below the spine of the scapula between the infra-spinatus and teres minor mus- cles. Mr. Key has found the tendon of the sub- scapularis torn across, together with the internal portion of the capsular ligament; the supra-spi- natus and long head of the biceps being stretched, but not ruptured. In the case of incomplete dislocation reported by Sir A. Cooper, the head of the bone was found to be thrown out of the glenoid cavity (fig. 106), lyin<* under the coracoid process upon the anterior part of the neck of the scapula*- the capsular muscles were not torn, but the long head of the biceps had been ruptured. The description given by Sir A. Cooper of this case, and reference to the illustrative plate in his work on " Dislocations," appear to point to a form of injury of the shoulder-joint which has of late years been specially described by the French surgeons as a variety of the dislocation downwards; that form of displacement, indeed, which by Boyer has been described as the dislocation "inwards," by Malgaigne the "subcoracoid " luxation, and by Velpeau as the "subpectoral" dislocation; in which the head of the humerus is placed in front of the neck of the scapula, and underneath the subscapular muscle. Why Sir A. Cooper described this as a partial dislocation, I do not understand; for not only was there rupture of the capsule and of the long tendon of the biceps, but the woodcut at page 401 of the last edition of his work shows clearly that the head of the bone had formed a new articular cavity for itself, in the subscapular fossa, being apparently completely thrown out of the glenoid cavity. It appears to me that the only dislocation of the humerus to which the term partial is strictly applicable, is that which has been described by Mr. Soden, in which the long tendon of the biceps is displaced from its groove or ruptured, and the head of the bone thrown upwards and forwards under the coracoid pro- cess, but not out of the glenoid cavity. It is to this form of displacement, also, that Air. Callaway seems disposed to confine the term partial. Dislocations of the shoulder-joint are almost invariably the result of falls upon the hand or elbow, the particular variety of dislocation depending upon the direction of the shock communicated to the arm and the position of the limb at the time of receiving it. On this account we almost invariably find the dis- placements in a direction inwards and downwards. When a person saves him- i'ni1"? Wlth J1S ,ams Widel? stretched' out, the head of the bone is driven with all the force of a long lever against the lower and inner portion of the cap- sule, which being ruptured in this its weakest part, allows the bone to be thrown UPm? 0rm \DSlde -°f the inferior costa of the scapula, and thus into the axilla When the patient falls upon his elbow, the inner part of the joint is still acted on, but the leverage not being so great, the head of the bone is thrown upwards or forwards under the clavicle. This dislocation is also often the result ot direct violence applied to the shoulder. The dislocation backwards can only take place when the arm happens to dislocations of the shoulder-joint. 251 receive the shock at the time that it is stretched across the chest. As this is an unusual position for any injury to be received in, this dislocation is proportion ately rare. An obstacle to this displacement may also be found in the great strength of the outer portion of the capsule of the joint as compared with the inner. Amongst these various dislocations those into the axilla are by far the most frequent, and that under the clavicle next. The displacement of the head of the bone under the spine of the scapula is so rare, that Sir A. Cooper only met with two cases of it; two cases have occurred at the University College Hospital; both were reduced without difficulty. The signs of dislocation of the humerus are sufficiently obvious, varying, however, according to the nature of the injury. In all cases there are six com- mon signs, viz., 1st, a flattening of the shoulder; 2d, a hollow.under the acro- mion; 3d, an apparent projection of this process; 4th, the presence of the head of the bone in the abnormal situation; 5th, rigidity; and 6th, pain about the shoulder. In the dislocation downwards — subglenoid (Fig. 104) the head of the bone can usually readily be felt in the axilla, at its anterior and under part; the arm is lengthened to the extent of about an inch, the forearm is usually somewhat bent, and the fingers often numbed, in consequence of the pressure of the head of the bone on the axillary plexus. The elbow is separated from the trunk and carried somewhat backwards, but can be approximated to the side. If the head of the bone cannot be felt in the axilla, its presence then may be ascertained, as Cooper directs, by raising the elbow from the side, when it at once becomes perceptible. In the dislocation forwards — subclavicular (Fig. 105) the head of the humerus can be felt and seen under the pectoral muscles beneath the clavicle; the arm is shortened, the axis of the limb being directed towards its head, and the elbow is a good deal separated from the side and thrown back. In the dislocation inwards — subcoracoid (Fig. 106) there is less deformity about the shoulder than in the other luxations, the acromion not forming so distinct a projection. The limb is somewhat shortened, the elbow being carried backwards and slightly away from the side; the head of the bone is placed deeply in the upper and inner part of the axilla, and cannot be very distinctly felt, owing to its being thickly covered with soft parts, by the coraco-brachialis as well as by the pectoral; rotation of the arm and elevation of the elbow being usually required in order that it may be detected. When the head of the bone is dislocated below the spine of the scapula (Fig. 107), it can be felt and seen there, more especially when the arm is rotated; the axis of the limb is likewise altered, being directed backwards. In the partial dislocation the signs do not appear to be very evident. In Mr. Soden's case there was slight flattening of the outer and posterior parts of the joint, and the head of the bone appeared to be drawn higher up in the glenoid cavity than usual. There was great pain induced by any movement of the biceps muscle, and on attempting any overhand motions the head of the bone became locked by the acromion. Dislocations of the humerus may readily be diagnosed from fractures of the anatomical and surgical neck of the bone, by the existence of the signs which are common to all luxations, and by the absence of crepitus. In fractures in this situation, also, the glenoid cavity always continues to be occupied by the head of the bone. The existence of crepitus, of slight shortening but little alteration in the axis of the limb, and no correspondence between this and the position of its head, are additional signs of value in establishing the diagnosis. Paralysis of the deltoid from a blow may simulate a dislocation, the shoulder being flat- tened and the acromion projecting; but here the mobility of the joint, and the 252 SPECIAL dislocations. presence of the head of the bone in the glenoid cavity, establish the absence of dislocation. The reduction of a dislocated humerus may be conducted on three different plans; — by the heel in the axilla — by the knee, or — by drawing the arm upwards. Whichever plan is adopted the patient should, if strong, be put under the influence of chloroform; when his muscles are paralyzed by this agent, but little force is required to effect the reduction, the surgeon's unaided strength usually sufficing for this purpose. If more power, however, should be required than he can exercise, extension may be made by assistants drawing upon a towel properly fixed round the lower end of the humerus, or else by the pullies attached to the same part of the limb. 1st. The reduction of the dislocation by the heel in the axilla is certainly the easiest procedure in ordinary cases. In adopting this plan, the patient is laid upon his back upon a low bed or couch; the surgeon seating himself upon the edge of this on the same side as the dislocated arm, takes the limb by the wrist, and fixing one foot firmly upon the ground, places the other, merely covered with the stocking, well up into the axilla, so that the heel may press against the lower border of the scapula, and the ball of the foot act upon the humerus (Fig. 109). He then draws the limb steadily downwards, and when it is dis- engaged to a sufficient extent, brings the hand across the patient, using his foot as a fulcrum, by which the head of the bone may be reduced by being Fig. 109. pushed upwards and outwards. This mode of reduction is especially service- able in ordinary dislocations into the axilla, and in those under the clavicle. In the latter, however, it will be necessary to draw the arm more obliquely downwards and backwards, and to press the foot somewhat forwards upon the head of the bone, after it has been disengaged by being brought below the coracoid process. 2d. The reduction by the knee in the axilla is precisely the same in principle as the last, though not by any means so good a plan; the knee being too large and not following the movements of the humerus so readily as the foot. In effecting the reduction by this means, the patient should be seated on a chair, and the surgeon standing by his side, and resting one foot upon the seat, place his knee in the axilla. He then seizes the patient's arm above the elbow with his right hand, and steadying the acromion with his left, draws the limb well down; then bringing it across the knee, the head of the bone is reduced. dislocations of the elbow. 253 3d. In some cases reduction is easily effected by laying the patient on his back, when the surgeon sitting behind him raises the arm perpendicularly by the side of the head, at the same time that he fixes the acromion. In this way the head of the bone is brought directly upwards into the glenoid cavity. If the patient is very muscular, or the dislocation of old standing, it may be necessary to have recourse to the pullies in order to effect reduction. In applying these the scapula must be firmly fixed, the counter-extension being made by passing the patient's arm through a slit in the middle of a jack towel, which should be fixed firmly to a hook or staple in the wall. The extending force may then be applied immediately above the elbow; and traction being made slowly and steadily in the direction of the axis of the limb, the head of the bone should be directed to the glenoid cavity by the pressure of the surgeon's hands, so soon as it has come to a level with it. In this way dislo- cations of the humerus of many weeks, or even months' standing, have been successfully reduced; but in employing these powerful means, especially under the influence of chloroform, the surgeon should always bear in mind that unless care be taken, serious mischief, even laceration of the axillary artery, may result. After dislocation of the humerus has been reduced, the limb should be bandaged to the side and supported in a sling; and if inflammation occur about the joint, leeches and evaporating lotions may be had recourse to. In compound dislocations of the humerus, the bone must be reduced as speedily as possible, and the wound closed, the local inflammation being combated by irrigation and other appropriate means. After reduction, there is a tendency for the head of the bone to be drawn upwards and outwards under and against the acromion, owing evidently to the deltoid and coraco-brachialis muscles not being any longer counterbalanced in their actions by those that have been separated from the head of the bone. Compound dislocation of the head of the humerus is a rare accident. I have known it occur in two directions, downwards and forwards. In it, even though the injury be extensive, it is better not to amputate if the brachial vessels and nerves be uninjured. The limb may then be saved by reducing the bone at once; after this the wound should be closed and dressed lightly, and kept cool by constant irrigation. If the axillary artery is ruptured, either completely or through its inner and middle coats, obstruction to the arterial circulation of the arm will ensue, and amputation must be performed through the articulation. When the dislocation is complicated with a fracture of the shaft of the bone, it should be reduced at once by putting the fracture up very firmly, and then attempting the reduction by one of the usual methods. In the case to which I have already referred, p. 244, I succeeded without difficulty by means of the heel in the axilla. The fracture must then be treated by lateral splints. Congenital dislocations of the shoulder-joint have only of late years attracted attention. Mr. Smith has ascertained, by post-mortem examination, the exist- ence of two varieties of this condition — the sub-coracoid and the sub-acromial luxations. In these there is wasting of the muscles of the shoulder and arm, the motions of which are extremely limited, whilst those of the scapula are pre- ternaturally great. The condition of the bones is also remarkable. In a case of congenital subacromial luxation of both shoulders there was no trace of a gle- noid cavity, but a well-formed socket existed on the outer side of the neck of the scapula, receiving the head of the humerus, which was small and distorted. These dislocations, though existing from birth, usually become more marked as age advances, but are necessarily irremediable in consequence of the malformation of the osseous structures and the wasting of the muscles. Dislocations of the Elbow are by no means unfrequent accidents, and as they are often occasioned by direct violence, in consequence of which much swelling speedily sets in, their signs are frequently obscured, and the diagnosis rendered proportionately difficult; more especially when the dislocation happens 254 special dislocations. to be complicated with fracture of the articular ends of the bones. In these cases indeed, it is only by a correct acquaintance with the normal relations of the osseous points, and by a comparison between those of opposite sides, that the surgeon can detect the true nature of the injury. The varieties of dislocation of the elbow-joint are very numerous, either both bones of the forearm or only one being implicated. The most common disloca- \ tion is that in which both [Fig. 110. bones are thrown backward* (fig. 110), with or without fracture of the coronoid pro- cess. This injury is readily recognized by the projection backwards of the olecranon, carrying with it the tendon of the triceps. The articu- lar end of the humerus also can be felt projecting in front of the elbow. When the coronoid process is not broken off, it is fixed against the posterior surface of the humerus, the forearm being immoveably placed in its new position. When this process is fractured there is great mobility about the joint, and crepi- tation may be felt as the arm is drawn forwards. Dislocation of both bones forwards can scarcely occur without fracture of the olecranon. There are, however, cases on record in which the bones have been so displaced without this process being broken. In this injury the elongation of the forearm, the projection of the condyles of the humerus, and the depres- sion of the posterior surface of this bone, render the diagnosis sufficiently easy. When the olecranon is broken off, there is elongation of the forearm and great mobility, but the detached fragment can be felt behind the humerus. The lateral dislocation of the bones of the forearm is almost invariably incom- plete; either the head of the radius hitching against the internal condyle, or the ulna coming in contact with the external one; complete lateral dislocation of the bones of the forearm being excessively rare. The only instance that I am acquainted with is a luxation outwards, reported by Nelaton, and of which he has given a woodcut. The ulna or radius alone may be displaced, and, in some cases, both bones are dislocated, but in opposite directions, thus complicating considerably the nature of the accident. The only dislocation to which the ulna alone is subject is that in a direction backwards. This seldom happens without more or less dislocation of the head of the radius. When it occurs it may be recognized by the projection of the olecranon backwards, and by the head of the radius being felt in its normal situation during the movements of pronation and supination. In the majority of cases the coronoid process would be fractured, at the same time causing ready disappearance and recurrence of the dislocation with crepitus. _ The radius alone may be dislocated forwards, backwards, or outwards. The dislocation forwards is certainly the most common. In the many instances of it that I have seen, it has resulted from a fall on the palm of the hand, by which the lower end of the radius being driven backwards, the upper end is tilted for- wards with the whole force of the leverage of the bone, and in this way, rup- turing the annular ligament, is thrown against the external condyle. The signs of this displacement are the following: — The forearm is slightly flexed and in a mid state between pronation and supination ; any attempt at the latter position occasions great pain, as does also the effort at straightening the arm. The elbow can only be bent at an obtuse angle, in consequence of the head of the radius resting against the lower end of the humerus (figs. Ill, 113). On rotating the dislocations of the elbow. 255 radius much pain is experienced, and the head of the bone can be felt to roll on the fore part of the humerus, the external condyles of which project unnatu- rally. The hand and arm can be fully pronated, but cannot be supinated more than half way. The whole of the outer side of the arm is deformed, being car- ried somewhat upwards (Fig. 112). The rupture of the annular ligament in this dislocation makes it very difficult to keep the head of the radius properly fixed, so as to prevent a recurrence of the displacement. In some cases, and indeed not unfrequently, there is incomplete dislocation of the radius forwards, arising either from falls upon the hand, or from violent twists of the forearm. In these we have the preceding signs, though to a less marked degree. The most characteristic symptom, however, is the inability on the part of the patient Fig. 111. Fig. 112. to flex the forearm upon the arm. This he can never do to a greater extent than to bring the elbow to a right angle (fig. 111). On being told to touch the tip of his shoulder with his forefinger, he will find it impossible to do so. The dislocation of the radius backwards is of extremely rare occurrence; it may always be recognized by the head of that bone being felt subcutaneously behind the external condyle; the movements of the elbow, and of the radius especially, being at the same time very limited and painful. The dislocation of the radius outwards is of more frequent occurrence than the last form of injury, the head of the bone being thrown on the outer side of the external condyle, where it is felt under the skin, rolling as the hand is moved. The natural motions of the joint are of course greatly interfered with. The radius and ulna are sometimes displaced in opposite directions, the ulna being thrown backwards, and the radius forwards. This injury, of which I have seen two instances at the Hospital, usually results from heavy falls upon the hand, with a wrench of the limb at the same time, as when a person is thrown out of a carriage, or lights upon his hands, in consequence of which the 256 special dislocations. Fig. 114. bones are twisted and displaced in opposite directions. The deformity is of course great, but readily recognized by the combination of the characters of the two forms of displacement, provided an examination be made before the swell- ing has come on, which rapidly sets in. Dislocations of the elbow-joint are very frequently complicated with fracture of one or other condyle of the humerus, of the olecranon, and, as we have already seen in displacement of the ulna, of the coronoid process. In these complicated injuries, an exact diagnosis is often extremely difficult, owing to the looseness and mobility of the parts, and to the great tumefaction that accompanies accidents of this description. It is in these cases that a good knowledge of the relative bearing of the different osseous points, aided by a comparative examination of the opposite limb, will alone enable the surgeon to effect a proper diagnosis of the nature of the injury. The mode of reduction in dislocations of the elbow-joint varies according as the ulna is displaced or not. When the ulna is dislocated, in whatever direction it may be thrown, and whether the radius be displaced at the same time or not, we shall find that the great obstacle to reduction is the hitching of the pro- cesses of that bone against the articular end of the humerus. If either the olecranon or coronoid process be fractured, this entanglement cannot take place, and the joint then slips into its position without difficulty, though it is very difficult to maintain it there. The reduction of the displaced ulna, when uncomplicated by fracture, may always be effected, as Sir A. Cooper has recom- mended, by bending the arm over the knee. The patient being seated on a chair, the surgeon rests one foot upon the seat, and placing the knee in the bend of the injured elbow, grasps the forearm with both hands; fixing the arm, he presses the knee firmly against the inner aspect of the forearm, so as to disengage the ulna from the lower end of the humerus, and at the same time he bends or pushes the fore-arm into proper position; into which, indeed, it has a tendency to return by the action of its own muscles, so soon as the op- posing osseous surfaces are separated (fig. 114). In dislocations of the radius, this movement across the knee is not neces- sary. All that is required is to fix the upper arm, and then employing exten- sion from the wrist to straighten the arm well, when, by bending the elbow at right angles, the head of the radius may be pressed into a proper position. After reduction has been effected, the limb should be firmly put up in lateral angular splints, the hand being kept semi-proned. If the radius has been displaced, a pad should be firmly ap- plied over its head, so as to prevent a return of the displacement, which is very apt to occur when the orbicular ligament is torn. The inflammation which usually results must be combated by the free application of leeches and of evaporating lotions. When this has subsided, passive motion may be commenced, and fric- tions and douches had recourse to, so as to remove the stiffness that is apt to be left about the joint. dislocations of the wrist. 257 Fig. 115. In those cases in which the dislocation is complicated with fracture of some part of the articular ends, and in which the diagnosis of the precise nature of the injury, owing to the swelling or other causes, has not been very clearly made out, the joint should be placed in as good a position as possible, by the process of traction, flexion, and moulding, so as to bring the osseous points into proper bearing with one another; the angular splints must then be applied, and local antiphlogistic treatment had recourse to. At the end of a month or five weeks, passive motion may be commenced, lest permanent rigidity come on, which is very apt to supervene. Compound dislocations of the elbow-joint require to be treated on the same principles on which compound fractures of this articulation are managed. Dislocations of both bones have been reduced some weeks after the occurrence of the accident, and of the radius alone at as late a period as two years after the displacement. Dislocations of the Wrist are of rare occurrence, so much so that their existence has been denied by Dupuytren and other modern surgeons. Although there can be no doubt that fractures of the lower end of the radius, more especially of an impacted character, have often been mistaken for these displacements, yet there can be no question that they do occasionally, though rarely, occur. Any doubt that may formerly have existed upon this point, in consequence of the want of post-mortem examinations, has been recently cleared up by the dissections of cases that have been made by Mar- jolin and Voillermier. The observations of these surgeons, together with those previously made by Sir A. Cooper, tend to show that dislocation of the hand from the carpus may take place either backwards or forwards (fig. 115). In whichever direction the accident occurs, a prominent smooth convex swelling, corresponding to the first row of the carpal bones, is felt and seen opposite the wrist. There is some shortening of the forearm, and the styloid processes of the radius and ulna form a projection on the opposite side to that in which the carpal tumor is seen. The facility with which the deformity is removed, and the displacement reduced, together with the general laxity of the wrist-joint, enable the surgeon to diagnose Fig. 116. the injury from im- pacted fracture of the radius. The existence of the convex swelling points out, that it is not a mere sprain of the wrist that has occurred. Besides these, an- other form of disloca- tion of the wrist may occur, in which the hand and the carpus are thrown forwards under the radius and ulna. This displacement, which has not, I believe, been previously observed, is illustrated in the accompanying figure taken from a cast sent to me by my friend Mr. Cadge (fig. 116). In it the projection of the styloid process of the ulna and the lower end of the 25S SPECIAL DISLOCATIONS. radius forming a slightly concave line, contrasts strongly with' the convex swellino' observed in the dislocation of the hand from the carpus (fig. 115). The treatment of these cases is simple: reduction, which is readily effected, must be maintained by the application of antero-posterior splints. Congenital Dislocations of the Wrist may take place either forwards or back- wards. The limb is in either case greatly deformed. The bones are shortened, and altered in shape, more especially the lower end of the radius. The muscles are also shortened, the extensor tendons forming a sharp angle as they pass over the carpus. Dislocations of single Bones of the Carpus are by no means of frequent occurrence. The bone that is most commonly displaced is the os magnum. This accident usually happens from falls, in which the hand is violently bent forwards, in consequence of which this bone starts out from its articulation, projecting as a round hard tumor on the back of the wrist opposite to the metacarpal bone of the middle finger. It may be readily reduced by being pressed upon at the same time that the hand is extended, thus pushing it into proper position. There is, however, a great tendency for this bone to slip out again, leaving considerable weakness of the joint, so much so that in two cases recorded by Sir A. Cooper, the patients found it necessary to wear artificial supports. The pisiform bone has been observed to be displaced by Evans and Fergusson, but I am not aware that dislocation of any other of the carpal bones has been described. A case, however, lately occurred to me at the Hospital, in which the semi-lunar bone appeared to be dislocated. The patient in whom this accident happened had fallen from a height, injuring his spine, and doubling his right hand under him. On examining the wrist, a small hard tumor was felt projecting on its dorsal aspect, which readily disappeared on extending the hand and employing firm pressure, but started up again so soon as the wrist was forcibly flexed. It was evident that this bone belonged to the first row of the carpus, articulating with the radius, and from its size, its position towards the radial side of the carpus, and its shape, which could be very distinctly made out through the integuments, there could be little doubt that it was the semi-lunar bone. The only metacarpal bone that admits of dislocation is that of the thumb; and though the articulation between this bone and the trapezium appears at first not to be of a character to resist much external violence, yet displacement of it seldom takes place. This is pro- bably owing in a great measure to the powerful muscles by which the bone is supported in all cases in which the force is applied upon its palmar aspect, as it most fre- quently is, as well as to the little leverage offered by so short a bone. These luxations, however, have been observed in two directions, backwards and forwards. The dislocations backwards, which are the most common, are often compound, arising from powder-flask or gun-barrel explosions in the palm of the hand, by which the joint is opened, and the bone thrown backwards. The reduction is in general easy, extension being made from the thumb by means of a piece of tape applied round the first phalanx. Dislocation of the metacarpophalangeal articulations are by no means of common occurrence, though occasionally met with (fig. 117). Most frequently the proximal phalanx of the thumb is the bone that is dislocated, being thrown backwards on the metacarpal bone. The signs of this accident are sufficiently evident, the prominence formed by the articular surfaces being distinctly marked. This dislocation of the proximal phalanx of the thumb has, owing to the diffi- culty of its reduction, attracted more attention than it would at first appear to DISLOCATIONS OF BONES OF THE CARPUS. 259 deserve. So great has this difficulty been in some cases as to render the dislo- cation irreducible, or to compel the surgeon to have recourse to operative interference in order to replace the head of the bone. The obstacle to the ready reduction of this small bone has been attributed to different causes. Thus, Hey supposed that it was owing to the constriction of the neck of the bone between the lateral ligaments of the joint; and Dupuytren entertained a very similar opinion, looking upon the position of these ligaments as the principal source of difficulty. The folding in of the anterior ligament of the joint and the interposition of a sesamoid bone between the articulating surfaces has also been looked upon as giving rise to this peculiarity. The more probable explanation, however, appears to be that the neck of the metacarpal bone becomes locked between or constricted by the two terminal attachments of the short flexor of the thumb, which must be carried back over its head, together with the displaced phalanx. The observations of Vidal, Malgaigne, and Ballingall, point to this as the cause. In many cases this dislocation may be reduced readily enough by the surgeon making extension with his fingers simply, and then pushing the bone into place; or, better still, after making some traction, by forcibly bending the pha- lanx towards the palm of the hand. If these means do not suffice, the hand should be fixed, and steady traction then be made from the phalanx, to which, previously protected by a strip of wet wash-leather, a piece of tape has been applied with a clove-hitch knot; or if more force be required, the pulleys may be used. In some cases the bone may be replaced by passing the ring of a door-key over the thumb, fixing one side against the projecting head of the phalanx, and then drawing and pressing this into its proper position. If all these means fail, subcutaneous section of the opposing muscle may be practised. If the dislocation be left unreduced, Sir A. Cooper says that the patient may still have a very useful thumb. In compound dislocation of this joint the bone may usually readily be replaced; should there be any difficulty its head must be removed, the dislocation being then reduced with great readiness, and the wound treated in a simple manner. [A novel and exceedingly successful method for the reduction of this trouble- some dislocation (fig. 118), has been practised by Dr. Crosby, of New Hampshire. Fig. 118. Fig. 119. He directs that the surgeon, seated by the side of the patient, should press up- wards and backwards the dislocated thumb, until the first phalanx assumes a posi- tion perpendicular to the metacarpal bone (Fig. 119). The base of the phalanx should then be pressed forwards by the thumb of the surgeon, when it will be found that flexion can easily be accomplished, and the joint restored to its natu- ral position. Dr. Crosby states that in the great number of cases which have 260 SPECIAL DISLOCATIONS. occurred to him, he has never failed to effect reduction in a single instance. Vide American Journal of the Med. Sciences, April, 1858.] Dislocation of the phalanges rarely occurs; when met Fig. 120. with, these displacements are readily recognized by the deformity they entail (fig. 120), and as easily reduced by pressure and traction in proper directions. In com- pound dislocation of the phalanges, the bone should be replaced, the finger supported by a pasteboard splint, and the wound dressed lightly. In some cases it is ne- cessary to remove the projecting end of bone before this can conveniently be done, anchylosis then results, a suffi- ciently useful finger being left. Dislocations of the Hip. — Notwithstanding the great depth of the acetabulum, the complete manner in which the head of the thigh bone is received into its cavity, the firmness of the capsular ligament, and the great strength of the capsular muscles that surround and support the joint, dislocations of the hip are more frequently met with than those of many other joints that appear less perfectly supported. This is doubtless in a great measure owing to the great length of leverage of the femur acting upon its head, when external violence is applied to the knee, and of that of the whole length of the lower extremity when it is applied to the foot. The different forms of dislocation of the femur have been expressed with great clearness and precision by Sir A. Cooper, who has shown that its head is most commonly thrown upwards and somewhat backwards, so as to lodge on the slightly concave surface between the acetabulum and the crista ilii, resting on the gluteus minimus, and having the trochanter turned forwards (fig. 121); or it may be thrown downwards into the foramen ovale lying upon the obturator externus muscle (fig. 123); or, forwards and upwards upon the horizontal branch of the pubes under the psoas and iliac muscles to the outer side of the femoral vessels (fig. 124). The head of the bone may also be thrown backwards into the sacro-sciatic notch, resting upon the pyriformis muscle (fig. 122). These are the four forms of dislocation of the hip, admitted by Sir A. Cooper, as of the more usual character; besides these, however, may be added, as not of very unfrequent occurrence, that form in which the bone is thrown backwards and somewhat downwards behind the tuberosity of the ischium. In addition to these, other less common forms of dislocation have been noticed; for instance, one in which the head of the bone lies between the anterior superior and the anterior inferior spinous processes of the ilium, or that in which it has been thrown upon the spine of the ischium. In all these various forms of dislocation there is rupture of the capsular ligament and of the ligamentum teres, with laceration of the muscles about the joint, and extravasation of blood into and around them. The signs, causes, and treatment of the different dislocations of the hip differ so greatly from one another that, practically, it becomes necessary to describe each of these displacements as a separate lesion. In considering these, we may reduce the more ordinary dislocations of the hip to four distinct varieties, besides which, however, it is necessary to bear in mind, that other and less usual forms of displacement may occur. The most common dislocation is that in which the head of the bone is thrown upwards and backwards upon the dorsum of the ilium, or rather upon that portion of the bone which extends between the acetabulum and the sacro-sciatic notch (fig. 121). This displacement differs so slightly in its pathology and treatment from the dislocation into the sciatic notch (fig. 122), described as a distinct variety of the injury by Sir A. Cooper, that 1 think it is more consis- dislocations of the hip. 261 tent with the true nature of these accidents to look upon them as essentially the same, the displacement in both cases being upwards and backwards, but in different instances partaking more of one or other direction. This dislocation may therefore be described as the ilio-sciatic. The next distinct dislocation is that in which the head of the bone is thrown downwards upon the obturator foramen, hence termed the thyroid dis- location (fig. 123). Fig. 121. Fig. 122. Fig. 123. Fig. 124. The third variety is the pubic, where the head of the bone is thrown upwards upon the pubes (fig. 124); and lastly, The sciatic dislocation, in which the bone is thrown downwards and back- wards behind the tuberosity of the ischium. Thus it will be seen that in whatever direction the displacement occurs, the head of the bone has a tendency to sink into some cavity or depression, or to lie upon one of the osseous surfaces in the neighborhood of the acetabulum. In the dislocation upwards and backwards or the ilio-sciatic, if the head of the bone rest upon the dorsum of the ilium, the hip will be found to be a good deal distorted, the gluteal region being somewhat prominent, and the upper part of the thigh enlarged, in consequence of the approximation of the muscu- lar attachments. The head of the bone can be felt in its new situation, more especially on rotating the limb; the trochanter is less prominent than natural, usually lying close against the brim of the acetabulum, and being turned 262 special dislocations. forwards; there is considerable shortening, varying from one and a half to three inches, and the position of the limb is remarkable, being distinctly rotated in- wards, with the thigh slightly bent upon the abdomen, and the leg upon the thigh, so that the knee is semi-flexed, and raised from the surface on which the patient is lying. The foot is inverted, so that the ball of the great toe rests on the ankle of the sound limb, and the heel is somewhat raised. The axis of the thigh is directed towards the sound knee (fig. 121). The movements of the joint are greatly impaired; abduction and eversion are not practicable, but in- version, abduction, and some flexion upon the abdomen, can be practised. When the head of the bone slips a little further back so as to become lodged in the sciatic notch, we have the dislocation backwards of Sir A. Cooper. In this the same symptoms exist, though to a less degree; hence the diagnosis is propor- tionately difficult (fig. 122). There is much less deformity about the hip in this variety of the displacement, owing to the head of the bone sinking into the hollow of the notch, and thus presenting the trochanter nearly in its usual position at right angles with the ilium, though somewhat behind and a little above its normal situation. In consequence of the head of the bone being received in a depression, the axis of the limb is not altered to the same extent as when it is thrown upon the plane surface of the dorsum ilii; hence the inversion of the knee and foot, though existing, is not so strongly marked. As the sciatic notch is but a little above the level of the acetabulum, the shortening of the limb is inconsiderable, not exceeding half an inch or an inch at most. The axis of the limb also is directed across the middle of the sound thigh in consequence of the bone being thrown further backwards. Thus the signs of these two forms of dislocation are nearly identical in character, though varying in degree, the principal difference being, that when the head of the bone rests upon the dorsum ilii, the axis of the femur is directed to the sound knee, whereas, when the head of the bone is lodged in the sciatic notch, the axis of the limb is directed across the middle of the sound thigh. The dislocation upwards and backwards is that which is most frequently met with in the hip. It is occasioned by violence acting upon the limb whilst abducted; with the body bent forwards upon the thigh, or the thigh upon the abdomen, as when a person is struck on the back with a heavy weight, or thrown forwards, or falls whilst carrying a heavy load upon his shoulders, when the upper and posterior part of the joint receives the whole of the strain. Under these circumstances, the capsular ligament is ruptured, and the bone slips out of its articulation. The diagnosis of this form of dislocation is easy in proportion as the head of the bone lies high on the dorsum ilii. The more it sinks towards and into the sciatic notch, the more difficult does the detection of the displacement become, and the greater the risk of its being overlooked altogether, or mistaken for a sprain. The only severe injury of the hip with which the dislocation upwards and backwards can be confounded, are those rare cases in which there is frac- ture of the neck of the femur, with inversion of the limb; here, however, the increased mobility, and the existence of crepitus, will enable the surgeon td effect the diagnosis. In ordinary cases of fracture of the neck, the existence of eversion of the limb at once points out that the head of the bone is not dislo- cated on the ilium. The reduction of this form of dislocation is effected in the following manner. The patient having been put under the influence of chloroform, is laid on his back upon a strong table between two staples, one of which should be fixed to the floor, and another at a point above the level of the body, in a direct line with the axis of the limb, and about twelve feet apart. The counter-extending force, consisting of a jack towel or of a padded leather belt, must then be passed between the injured thigh and perineum, and fixed to the staple in the floor. The pulleys must now be attached to proper straps or to a towel fixed dislocations of the hip. 263 with a clove-hitch knot immediately above the knee, by one end; the other extremity being attached to the staple in the wall, which should be so situated as to be continuous with the axis of the lower part of the limb. The knee being then slightly bent and rotated inwards, traction is applied slowly and steadily until the head of the bone has approached the acetabulum, when the surgeon rotates the limb inwards so that the head may slip into its socket (fig. 125). If difficulty occur in raising the bone over the acetabulum, the Fig. 125. plan recommended by Sir. A. Cooper, of passing a towel under the thigh to enable an assistant to lift the head of the bone over the brim of that cavity, maybe had recourse to. The fact of the reduction being accomplished, is ascer- tained by comparing the bony points of the limb with those of the opposite side, and seeing if they correspond. A long splint and spica bandage should now be applied to fix the thigh, and the patient be kept in bed for a fortnight, so that reunion of the ruptured tissues may take place. In reducing this dislo- cation, there is some danger of the head of the bone slipping downwards into the sciatic notch, if the limb be too much raised. This accident, which has happened to some very excellent surgeons, may be mistaken for reduction of the bone, a serious mistake, that would, unless corrected, entail permanent lameness on the patient. When the bone is thrown upon the sciatic notch, the reduction is difficult, and a slight modification of the treatment is required; this consists in laying the patient on his sound side instead of on his back, and making extension across the middle of the sound thigh instead of immediately above his knee, as in the last case. In the reduction of this dislocation, also, Sir A. Cooper gives the very valuable advice, of lifting the femur out of the notch and over the edge of the acetabulum by means of a round-towel placed under the upper part of the thigh and over the shoulders of an assistant, who at the same time should rest his limbs on the patient's pelvis, and then raising his head draw the bone towards its socket. Reduction of dislocations on to the dorsum ilii or sciatic notch, may be effected readily enough whilst the patient is under chloroform, by " manipulation" of the limb, as introduced by Dr. Reid, of Rochester, TJ. S. This is done by flexing the leg on the thigh, carrying the dislocated thigh over the sound one, upwards across the pelvis, as high as the umbilicus, and then by abducting and rotating it outwards. In the dislocation downwards into the obturator foramen we find the hip flattened, and the prominence of the trochanter completely absent, or indeed replaced by a depression. The limb is lengthened by about two inches, ad- vanced before the other, and considerably abducted (fig. 123). The knee is bent and incapable of extension; the foot usually points forwards, but is sometimes 264 SPECIAL DISLOCATIONS. slightly everted, and is widely separated from its fellow. The body is bent forwards in consequence of the tension of the psoas and iliac muscles, and in thin persons the bone may be felt in its new situation. This dislocation appears to be occasioned by the limb being suddenly and violently abducted, as by falls, with the legs widely separated; in consequence of which the head of the bone is tilted against the inner side of the capsule; and rupturing this, is thrown into the thyroid notch. In the reduction of this dislocation the patient should be placed upon hia back, the counter-extending girth, or towel, is then placed round the pelvis, and fixed firmly to a staple next to the sound side of the patient. A padded girth is then to be placed between the perineum and the upper part of the dislocated thigh. From this, extension is made by means of the pulleys or the tourniquet, which are fixed to a staple at a little distance from the injured side of the patient. Extension having then been made to such a degree as to elevate the head of the bone from the depression in which it lies, the surgeon passes his hand behind the sound leg, and seizing the ankle of the injured limb, draws it backwards and towards the mesial line, taking care to keep the knee straight, and thus throwing the head of the bone into the acetabulum by the action of a long lever (fig. 126). The dislocation upwards (fig. 124) on the pubes presents very unequivocal signs. The hip is flattened; the head of the bone can be distinctly felt lying in its new situation above Pou- part's ligament, to the outer side of the femoral vessels, where it may be made to roll by rotating the limb. The thigh and knee are slightly flexed, rotated outwards, and abducted; the limb, which is separated from its fellow, is shortened to the extent of an inch. I he cause of this dislocation is either direct violence applied to the back of the thigh whilst the limb is abducted, or from the patient making a false step m walking, and suddenly throwing his body backwards in order to avoid a fall, twisting and displacing the limb. With regard to the treatment, Sir Astley Cooper advises that the patient should he upon his back, with his legs widely separated; and that counter- extension being then made by a girth carried between the perineum and the injured thigh, and fixed to a staple in front of and above the body, the pulleys should be fixed upon the lower part of the thigh, and the extension made down- wards and backwards. After this has been continued for a sufficient time, an assistant lifts the head of the bone by means of a towel over the brim of the acetabulum (fig. 127). DISLOCATIONS OF THE PATELLA. 265 The dislocation behind the tuberosity of the ischium is of very rare occur- rence. Fig. 127. Dislocations of the patella are not frequently met with. They may, however, occur in four directions, viz. outwards, inwards, upwards, and edge- ways or vertically. The dislocation outwards is the most common variety of the accident, the bone being thrown upon the outer side of the external condyle of the femur, with its axis directed somewhat backwards and downwards. The knee is flattened in front, and is broader than usual; the patella can be felt in its new situation, and the muscles that form the quadriceps extensor are rendered tense, mere especially the vastus internus; the leg is sometimes extended, but more frequently the knee is slightly flexed. This accident usually happens from sudden muscular contraction in persons who are knock-kneed. In some cases it has been occasioned by direct violence, driving the bone out of its position. Most frequently the dislocation is not quite complete, the patella being only partially displaced outwards, with some rotation of the bone in the same direction. The dislocation inwards is of very rare occurrence; Malgaigne, who has investigated this subject, being of opinion that there is only one case of the kind on record. In these lateral dislocations, reduction may be effected by laying the patient on his back, bending the thigh on the abdomen, and raising the leg so as to relax the extensor muscles. The surgeon then, by pressing down that edge of the patella which is furthest from the middle of the joint, raises the other edge, which, being tilted over the condyles, is immediately drawn into position by the action of the extensors. A remarkable form of dislocation of the patella is that in which this bone becomes twisted upon its axis in such a way that it is placed vertically, one of its edges being fixed between the condyles, or upon the external one, and the other projecting under the skin, and pushing this forwards into a distinct tumor. In some cases the bone is turned almost completely round, the pos- terior surface becoming partly anterior. The signs of this dislocation are evident, manual examination indicating the vertical displacement of the patella, with a deep depression on either side. The limb is completely extended, flexion being impossible. This peculiar dislocation has most generally arisen from sharp blows or severe falls upon one edge of the patella, whilst the limb was semi-flexed, in consequence of which the bone appears to have been semi-rotated and fixed in its new position. Violent muscular contraction, however, conjoined with a twist of the leg, but without any blow, has been known to occasion it in some cases. 266 SPECIAL DISLOCATIONS. The reduction of this displacement is always attended with great difficulty, and indeed in some cases has been found to be quite impracticable —surgeons having ineffectually attempted, by means of elevators and the section of the tendons, to replace it, and the patient having eventually died from traumatic suppuration of the joint, with the displacement unrelieved. The cause of this difficulty of reduction is not very distinctly made out: it is certainly much greater than can be explained by simple muscular contraction, and may not improbably be owing to the resistance offered by the aponeurotic structures which cover the bone becoming twisted or entangled under it, or, as Malgaigne supposed, by the superior angle of the bone being wedged in the subcondyloid space. If relaxation of the muscles of the thigh, and the employment of proper pressure upon the patella, do not succeed, reduction may perhaps be effected by directing the patient to make a sudden and violent muscular effort at extension of the limb, or by attempting to walk. In other cases, again, it may be readily replaced by bending the leg, and rotating it on the axis of the tibia at the same time that the patella is pressed into position, as Vincent recommends. Should these plans not answer, I do not think it would be advisable to have recourse to subcutaneous section of the tendon of the quadriceps extensor and of the ligamentum patellae. In one case, in which both these structures were divided, the patella remained as firmly fixed as ever, and the patient eventually died of suppurative inflammation of the knee-joint; and in no case in which it has been practised, does it appear to have facilitated the reduction of the bone. Dislocation of the patella upwards can only occur as a consequence of the rupture of its ligament. This accident, which is always accompanied by much inflammation of the joint, requires the same treatment as a fractured patella. Dislocations of the Knee. — This joint, owing to the breadth of its arti- cular surfaces, and the great strength of its ligaments, is seldom dislocated. When such an accident happens, it usually arises from falls from a great height, or by the patient jumping from a carriage in motion. The tibia may be displaced in four directions: forwards, backwards, or to either side. Besides these displacements, the joint is subject to a partial luxation dependent upon displacement of the semi-lunar cartilages. The lateral dislocations of the tibia are the most common. They are always incomplete, and are usually accompanied by a certain degree of rotation of the limb in an outward direction. These displacements may either be external or internal. In the first, the outer condyle of the femur rests upon the inner articular surface of the tibia. In the other, the inner condyle is placed upon the outer articular surface of the head of this bone. In either case the knee is slightly flexed; there is a marked sulcus in the situation of the ligamentum patellae; the extensor muscles of the thigh are relaxed, and the deformity of the joint indicates at once the nature of the displacement to which the bones are subject. In these cases reduction is always easy; indeed, occa- sionally it is effected by the unaided efforts of the patient, or by a bystander. It may be accomplished by flexing the thigh upon the abdomen, then extending the leg, and, at the same time, by a movement of rotation replacing the bones in proper position. The dislocation backwards may be complete or incomplete. When complete, the posterior ligament of the joint is torn, the muscles of the ham are stretched, the limb is shortened to the extent of an inch and a half or two inches, and is semi-flexed; the head of the tibia can be felt in the ham, and there is a deep transverse depression in front of the joint immediately below the patella. The dislocation of the tibia forwards is of more frequent occurrence than the last accident. In it, the lower end of the femur is felt projecting into the ham, compressing the vessels to such an extent occasionally as to arrest the circula- DISLOCATIONS OF THE KNEE. 267 tion through the lower extremity, lacerating the ligaments and stretching the muscles in this situation. The tibia is felt to project forwards, its head forming a considerable prominence on the anterior part of the knee, with a deep depres- sion immediately above it and the patella, which is rendered more evident by the extensors of the thigh being relaxed; the leg is usually rotated somewhat inwards or outwards, and there is shortening to the extent of about two inches. These antero-posterior dislocations are very commonly incomplete. When this is the case, they present the same symptoms, but to a less marked degree, that characterize the comple displacements. In the treatment of these dislocations, extension should be made from the ankle whilst the thigh is fixed in a semiflexed position; when the leg has been drawn down sufficiently, proper manipulation will bring the bones into accurate position; splints must then be applied, means taken to subdue local inflamma- tion, and the joint kept perfectly at rest for two or three weeks, at the end of which time passive motion may be commenced. The subluxation of the knee, or "internal derangement of the knee joint,'' is an accident of more frequent occurrence than any of those that have just been described. It usually occurs by the patient, whilst walking, striking his toe against or tripping upon a stone, when he is suddenly seized with acute and sickening pain in the knee, often so severe as to cause him to fall to the ground. Before doing so, however, he is conscious of having strained or otherwise injured the joint. On examination it will be found semiflexed, the patient being unable to extend the limb properly, and every effort being attended by Severe pain. In the course of a very short time the joint becomes swollen, being distended by synovial secretion, and symptoms of subacute synovitis are speedily superadded to the original injury. This accident, originally described by Hey, and since investigated by Sir A. Cooper and others, is owing to the semilunar fibro-cartilage slipping away from under the internal condyle, either before or behind it, so as to bring its surface and that of the tibia into direct apposition. The severe pain that is always experienced is owing, in all probability, to the nipping of the loose folds of synovial membrane that lie within the joint, and that go by the name of the mucous and alar ligaments, and also to the great stretching of the ligaments by the partial displacement of the bones. The reduction may be effected by flex- ing the joint, and then, when the muscles are off their guard, the patient's atten- tion being directed elsewhere, rapidly extending it at the same time that a movement of rotation is communicated to the leg. The evidence of complete reduction consists in the power of extending the articulation being regained by the patient. The synovitis that usually follows upon this injury requires to be treated by local antiphlogistics and rest. After it has been subdued, the patient should wear a laced knee-cap, as the joint will be weakened and liable to a recurrence of the same injury. Dislocations of the knee-joint are more liable to serious complications than those of any other articulation. Not only are the ligaments torn, and the mus- cles injured, but stretching and perhaps laceration, of the popliteal vessels, fol- lowed by gangrene of the limb, may occur; or the joint may fall into a state of suppurative and destructive inflammation, as the result of the injury. Compound dislocation of the knee-joint constitutes one of the most serious injuries to which the limbs are liable; the external wound being usually large, ragged, and accompanied by the protrusion of the condyles of the femur, with much laceration of the soft structures in the vicinity of the joint. These are cases that certainly, as a general rule, call imperatively for amputation; indeed, Sir A. Cooper looks upon this injury as especially demanding removal of the limb. Cases, however, have occurred in which the limb, even under these cir- cumstances, has been saved. Hence, if the patient is young, and if the vessels of the ham do not appear to have been seriously injured, the wound in the soft 268 SPECIAL DISLOCATIONS. parts at the same time not being very extensive, or much bruised, an attempt may, with propriety, be made to save the joint. In a case of compound dislo- cation of the knee forwards, in a boy, the late Mr. A. White sawed off the pro- jecting end of the femur which protruded through the ham, and bringing the wound together, succeeded in saving the limb. The head of the fibula has occasionally, though very rarely, been displaced by the application of direct violence to it. Boyer and Sanson have each recorded a case of this kind. Dislocations of the ankle occur in consequence of displacement of the astragalus from the bones of the leg, whilst it continues to preserve its normal connection with the rest of the foot. These dislocations are almost invariably connected with fracture of the lower end of the fibula, or of the inner malleolus. In fact, in looking at the arched cavity into which the astragalus is received, it is evident that this bone can scarcely be displaced laterally without fracture of one side of this arch. In considering these dislocations we must, in accordance with the general nomenclature of similar accidents, in which the distal part is always said to be displaced from the proximal, look upon the foot as being dis- located from the leg, and not consider the tibia as being displaced upon the foot. The direction of the dislocation must consequently be determined by the position into which the articular surface of the astragalus happens to be thrown. It is necessary to explain this, inasmuch as a good deal of ambiguity occurs in surgical writings from the same accident being described differently, according to the view taken of the part displaced. Thus, Sir A. Cooper speaking of the tibia as being dislocated at the ankle, whilst Boyer and others regarding the foot as the part displaced, have described the same injury in directly opposite terms. Dislocations of the foot may take place in four directions, viz., laterally, on either side; backwards, and forwards. In all cases, the injury appears to be occasioned either by the foot being twisted under the patient in jumping or running: or else by its being suddenly arrested by coming in contact with the ground whilst the body is carried forwards. The dislocation outwards is of most frequent occurrence. In it the inner malleolus projects forcibly against the skin; there is a depression above the outer ankle corresponding to a fracture of the fibula, and the sole of the foot is turned upwards and outwards; the inner side touching the ground, whilst the outer edge is turned up. (Fig. 128). In the dislocation inwards, which [Fig. 128. is a rare accident, and according to Sir A. Cooper, a much more dan- gerous one than that just described, the fibula is not fractured, but the lower end of the tibia is splintered off, in an oblique manner, from within outwards. The outer edge of the sole rests against the ground, and the inner side is turned up- ward. The reduction of these lateral dis- placements is readily effected by simple traction into proper position; leg-splints with lateral foot-pieces must then be put on, or Dupuy- tren's splint may be applied on the same side as the dislocation, opposite to that on which the eversion of the foot takes place. In the dislocation of the foot backwards, the deltoid ligament is ruptured, the dislocations of the astragalus. 269 fibula broken in the usual situation, and the tibia thrown forwards on the navi- cular and internal cuneiform bones; the foot is consequently shortened, and the heel rendered more projecting. The dislocation forwards, in which the foot is lengthened, and the tibia thrown upon the upper and posterior surface of the os calcis, behind the astragalus, is an accident of such rare occurrence as seldom to have been witnessed, although described. In the treatment of these antero-posterior displacements of the ankle, traction of the foot in a proper direction, the leg being fixed and flexed upon the thigh, will readily be attended by replacement of the bones, the application of lateral splints being afterwards sufficient to keep the parts in proper position. Compound dislocations of the ankle-joint are serious, but by no means unfre- quent accidents, the displacement occurring in the same direction and from the same causes as the simple forms of injury. The treatment of these cases must depend to a considerable extent upon the amount of laceration of the soft parts, and the condition of the bones forming the arch of the joint. If the wound in the soft parts be not considerable in extent, clean cut, and with little injury to the bones, the limb should be placed on a M'Intyre's splint; and the lips of the wound, being well cleaned, brought together by strapping, or covered by lint soaked in collodion; evaporating lotions may then be applied, the constitutional condition of the patient carefully attended to, and the case treated much in the same way as a compound fracture. In many instances this plan will suffice, and the patient will recover with a useful limb, the joint being only partially anchylosed. If, however, the bones be projecting and comminuted, and the wound more extensively lacerated, the question of amputation will necessarily arise. In many cases the operation may be dispensed with by adopting the treatment recommended by Mr. Hey, of sawing off the malleoli, removing splinters of bone, cleaning the wound, bringing together its edges by simple dressing, and supporting the limb at the same time upon a M'Intyre's splint. If the joint be still more seriously injured, the posterior tibial artery torn, or the foot greatly contused, or if the patient's constitution be shattered and irritable, primary ampu- tation should be had recourse to. I believe, however, that the disinclination on the part of surgeons to amputate in these cases, owing to the strong expression of opinion by Sir A. Cooper in favor of the attempt to save the limb, has in many cases been carried to such an extent as seriously to endanger the patient's life. Secondary amputation may be rendered necessary, in consequence of gan- grene, erysipelas, or extensive suppuration. Dislocations of the Astragalus. — The astragalus is occasionally dis- placed from its connection with the bones of the leg above, and with those of the tarsus below, being thrown either forwards or backwards, the displacement for- wards happening far more frequently than that in the opposite direction. In the dislocation forwards, the head of the bone may be thrown either outwards or inwards, but I do not think there is any evidence to show that complete lateral dislocation of this bone can occur irrespective of displacement forwards; the so-called lateral dislocations being displacements of the bone forwards, with twists to one or other side. In the luxation backwards there is no rotation of the bone, which is thrown directly behind the tibia, in the space between it and the tendo Achillis. These dislocations invariably happen from falls upon, or twists of the foot; more particularly when it is in a state of extension upon the leg. When the foot is in this position, the lower end of the tibia either breaks off on the appli- cation of sufficient violence, or the head of the astragalus is forced out of the cavity of the scaphoid, and its bed on the os calcis, the particular kind of dis- placement that occurs depending upon the direction in which the force is acting and in which the foot is twisted. The dislocation of the astragalus forwards with twist of the bone inwards, is 270 special dislocations. said to be of most common occurrence, although I have more frequently wit- nessed that form of accident in which the bone is thrown somewhat outwards as well as forwards. In either case the displaced bone forms a distinct tumor upon the instep, in the outline of which the form of the astragalus can be dis- tinctly made out. Over this, the skin is so tightly drawn as often to appear to be on the point of bursting. When the bone is thrown somewhat inwards the foot is turned outwards, and the internal malleolus projects distinctly. When the astragalus is thrown outwards, displacement of the foot in an inward direc- tion, with great projection of the lower end of the fibula, takes place.. In some cases, fracture of the neck of the astragalus is conjoined with these dislocations, and not uncommonly the luxation is compound from the very first, or speedily becomes so if left unreduced, in consequence of the sloughing of the skin which covers the anterior surface of the bones, the exposed portion of which under- goes necrosis, and perhaps, eventually, exfoliation. The dislocation backwards into the hollow, under the tendo Achillis, is of rare occurrence, there being but seven recorded instances of this accident. In the majority of these there was displacement of the bone inwards, as well as backwards. In these cases the diagnosis is easy, as the bone forms a distinct prominence, which can be felt under the tendo Achillis. In many cases the dislocation of the astragalus is not altogether complete, the under surface of the tibia not coming into direct contact with the upper surface of the os calcis; a portion of the astragalus still intervening between these articulations. The reduction of the dislocation forwards, whether attended by lateral dis- placement or not, varies greatly in the facility of its execution ; in some instances being effected with the greatest possible ease, in others being attended by almost insurmountable difficulties. This difference in the facility of reduction depends, I think, on whether the dislocation is complete or not. When the astragalus is not completely thrown from under the arch formed by the bones of the legs, a portion of it being still entangled between their articular surfaces and that of the calcaneum, it may usually be readily reduced by relaxing the muscles of the calf, and pushing the bone back into its proper position. But when the astra- galus is completely dislocated, the upper surface of the calcaneum is drawn up under the arch of the malleoli by all the strength of the muscles that pass from the leg to be inserted into the foot. Under these circumstances, in order that reduction take place, it is necessary first of all to separate the articular surfaces to such an extent as to admit of the astragalus being pushed back into its socket; this is almost impossible, owing to the great perpendicular thickness of this bone, to the extent to which it is consequently necessary to draw down the foot, and to the little purchase that can be obtained on it. In such cases as these, the reduction has been greatly facilitated by the division of the tendo Achillis, by which simple operation the whole strain of the muscles of the calf is taken off. 4 If reduction is still impracticable, the bone must be left in its new situation. If this be in the direction forwards, the skin will usually slough, and then a por- tion of the exposed osseous surface, which will probably necrose, may be excised, or the whole of the astragalus dissected out by freely exposing it and severing its ligamentous attachments; the patient recovering with a somewhat stiffened, but still useful, joint. This plan appears to be safer than excising the bone in the first instance so soon as the dislocation has been found to be irreducible. In luxation backwards, the bone has not hitherto been reduced, except in one case which occurred in University College Hospital, and in which the tibia and fibula were fractured. It is by no means improbable that subcutaneous division of the tendo Achillis may in future enable the surgeon to do this. The result is, however, satisfactory, even though the bone be not noticed, the patient recovering with a useful foot. If left unnoticed, the soft parts covering the dislocations of the foot. 271 bone may slough, as happened in a case recorded by Dr. Williams, of Dublin, in which the bone was consequently extracted. In compound dislocation of the astragalus (fig. 129), the rule of practice must depend upon the extent of injury. If the integuments have merely been rent in consequence of the tension to which they Fig. 129. have been subjected by the outward pressure of the displaced bone, an attempt must be made to reduce the dislocation, and if this be effected, to close the wound by the first intention. If the bone be comminuted as well as dislocated, the proper practice will be to remove the loosened frag- ments, and to dress the wound in the simplest manner, allowing it to heal by granulation. If the bone be irreducible, it is a question whether it should be left or dissected out. If it be left, the wound in the integuments will certainly extend by a sloughing pro- cess, the bone will inflame and become carious or necrosed, exfoliating in frag- ments, and the patient will only recover after a prolonged, tedious, and dan- gerous course of treatment. Under these circumstances, therefore, it appears to me that the simpler and safer plan both to limb and life consists in enlarging the wound in proper directions, so as to dissect out the irreducible astragalus, and then bringing the articulating surfaces in contact, dressing the parts lightly, and trusting to the formation of a new joint between the tibia and the os calcis. So, also, if a simple dislocation of the astragalus become compound in conse- quence of the sloughing of the superjacent tense integuments, the exposed and necrosing bone should be removed in part or in whole, according to the circum- stances of the case. If, together with the dislocation of the astragalus, the foot be extensively crushed, amputation may be required either at the ankle-joint or at some convenient part of the leg. Dislocation of the other tarsal bones is of extremely rare occurrence. Most of them, however, have been found to have been luxated at times. Thus, for instance, the calcaneum has been dislocated laterally from its connections with, the cuboid in consequence of falls from a height, the sufferer alighting upon his heel. Chelius mentions a case in which this bone was dislocated by the effort of drawing off a tight boot. The reduction seems to be readily effected by relaxing the muscles, and pressing the bone back into its proper position. The scaphoid and cuboid bones have been found to be dislocated upwards in consequence of a person jumping from a height and alighting upon the ball of the foot. In these instances the limb is shortened and curiously distorted, the toes pointing downwards, the arch of the instep being increased so as to resem- ble closely enough the deformity of club-foot. Reduction may be effected by drawing and pressing the parts into position. The great cuneiform bone has occasionally been found to be dislocated. Sir A. Cooper mentions an instance of this kind. If reduction be not effected by pressing the bone into its position, no great evil appears to result to the patient, the motions of the limb not being seriously interfered with. Dislocation of the metatarsal bones, though excessively rare, from the manner in which they are locked in between the bones of the tarsus, and retained by short and strong ligaments, yet occasionally occurs; instances being recorded by Dupuytren and Smith. Liston also mentions a case of luxation of the meta- 272 injuries of the head. tarsal bone of the great toe from direct violence. Tufnell records a case of luxation downwards and backwards of the three internal metatarsal bones, from a fall upon the leg by a horse rolling on its rider. Luxations of the pha- langes of the toes but rarely happen, and present nothing special in nature or treatment. Besides these instances of dislocations, properly so called, it occasionally hap- pens that accidents are met with that may in strictness be referred to this head, though differing somewhat from the usual characters of luxations. Thus, for instance, the sutures of the skull are occasionally separated, in consequence of blows on the head. So also the articulations between the vertebrae may suffer displacement. These injuries, however important, from the effects produced upon the contained organs, will be considered in the next chapters when treating of injuries of the head and spine. It occasionally happens, that in consequence of severe blows upon, or com- pression of, the pelvis, the symphysis of the pubes, or the sacro-iliac articulation, is displaced; here the nature of the injury is indicated by the deformity that results, and the same treatment is required as in fractured pelvis. The lower angle and dorsal border of the scapula is occasionally the seat of a very remarkable kind of displacement, in consequence of which it projects at a considerable angle from the trunk, giving a winged appearance to the back. The cause of this peculiar displacement is somewhat obscure; by some it is considered to be dependent upon the bone slipping away from under the poste- rior edge of the latissimus dorsi muscle; by others again, and apparently with more reason, it is considered to be owing to paralysis of the serratus magnus. Whether this be dependent upon some morbid condition of the muscle itself, as Dr. Jacob supposes, or be owing to a paralyzed state of the long thoracio nerve, as Nelaton thinks, can scarcely be determined. In such cases as these, I have seen some benefit derived from the endermic application of strychnine on a blistered surface, and afterwards support by means of a properly constructed apparatus. INJURIES OF REGIONS. CHAPTER XVIII. INJURIES OF THE HEAD. The consideration of injuries of the head is one of the most important studies that can engage the surgeon's attention. The importance attached to it is not so much due to the special considerations connected with the mere injury of the scalp and cranium; but rather to the effects that are produced as the result of the implication of the brain and its membranes, in many cases directly, and in others indirectly, owing to the close connection that subsists between the actions that take place in the external and internal structures of the head. In conse- quence of this tendency to cerebral complication, it is of the first moment in practice to study these injuries as a whole, and with special regard to those affections of the encephalon produced by them; and from which the injury of the scalp and the fracture of the cranium derive the greater part of their im- portance. It is therefore necessary in the first instance to be acquainted with the nature and treatment of the principal forms of cerebral affection that super- CEREBRAL DISTURBANCE. 273 vene upon these accidents, before we proceed to study the special nature and peculiar modifications of treatment required by the conditions that occasion them. CEREBRAL DISTURBANCE. There are two principal states of functional disturbance arising from injury to which the brain is subject, viz., concussion and compression ; either of these may be followed by, or be complicated with, inflammatory actions of various kinds, that derive much of their peculiar characteristics from the condition with which they are associated, and from the injury by which they are occasioned. 1st. Concussion or stunning appears to be a shock communicated to the nervous system from the application of such external violence as will produce commotion of the substance of the brain, or interfere with the circulation through it; in consequence of which its functions become temporarily sus- pended, usually in a slight and transitory degree, but occasionally to such an extent that the patient does not rally for many hours from the depressed state into which he is thrown, and perhaps sinks without recovery. In those cases in which death immediately results from the continuance and severity of the concussion, either no lesion at all may be found in the cerebral substance, or it may have been rendered so soft and semi-diffluent by the shock to which it has been subjected, as to be evidently incompatible with life, even though no dis- tinct rupture of its substance appears to have taken place. In other cases, again, more serious injury, such as rupture of it, may have occurred. In the slighter cases of concussion — that degree indeed which invariably accompanies any severe injury of the head—the surface becomes cold and pale; the sufferer is motionless and insensible, or only answers when spoken to in a loud voice, relapsing again into speedy insensibility, or rather semi-conscious- ness; the pulse is feeble, the pupils contracted, and the sphincters usually relaxed; the limbs are flaccid, and muscular power is lost. After continuing in this condition, which is the first stage of concussion, for a few minutes or hours, according to the severity of the shock, the second stage comes on, the circula- tion gradually re-establishing itself, the pulse becoming fuller, and the surface warmer. About this time the patient very commonly vomits; the straining accompanying this effort appears to be of service in stimulating the heart's action, and driving the blood with more vigor to the paralyzed brain, thus tend- ing to restore its functions; and we accordingly find that, after vomiting has occurred, the sufferer quickly rallies. In the more severe cases, the symptoms that have just been described are so strongly marked that the patient appears to be moribund; there is complete prostration of all nervous and physical power; the surface being cold and death-like, the eyes glassy, the pupils either con- tracted or widely dilated, the pulse scarcely perceptible and intermittent. In this state the patient may lie for hours, recovery being slow, and the concussion merging into some other, and perhaps more serious affection of the nervous centres, or, indeed, in some cases, speedily terminating in death, apparently by failure of the heart's action. The terminations of concussion are various. We have already seen that in some cases this affection may speedily give way to complete recovery, although slight headache, some degree of giddiness, confusion of thought, and inaptitude for mental occupation, may last for a few days before the mental powers are completely re-established. In other cases again, the concussion may rapidly terminate in the patient's death, but between these conditions there are several intermediate states. Thus the recovery may be complete, but a permanently irritable state of brain may be left, the patient, though capable of the ordinary duties of life, becoming readily excited by slight excesses in diet or in the use of stimulants, or by mental emotion, though not of an inordinate intensity. These individuals, suffering from a preternaturally irritable brain frequently die 274 INJURIES OF THE HEAD. suddenly in the course of a few months, or a year or two, after the receipt of the injury. In other cases the recovery continues to be incomplete, although the patient may be enabled to follow his usual occupation, and to mix in the ordinary business of life; but yet his state is a precarious one, the brain being liable to the occurrence of inflammatory disease on the slightest exciting cause. In such cases as these, there is frequently a certain degree of impairment of mental power, the memory failing either generally or in certain important points, as with reference to dates, persons, places, or language. The speech is perhaps indistinct and stuttering. Amaurosis of one or both eyes, with perhaps squint- ing or paralysis of the eyelid, may be left. The hearing may be impaired, or noises of various kinds set up in the ears. There may be diminution or loss of muscular and of virile power, especially, as Hennen observes, in those cases in which the injury has been inflicted upon the back of the head; and Holberton has noticed that when the medulla oblongata has been injured, the pulse may continue preternaturally slow—an observation that I have had several opportu- nities of confirming in injuries both of the medulla, the pons, and the crura cerebri. For these symptoms to occur, it is by no means necessary that the original local injury should have been a severe one. In some cases, in railway accidents more especially, or in falls from a height, the whole nervous system appears to be jarred and concussed without any wound or apparent sign of internal injury of the head. At first the symptoms of concussion are but slight, perhaps even none are apparent, and the sufferer congratulates himself on his escape, but gradually impairment of nervous power, manifesting itself in one or other of the ways just mentioned, comes on, and the health continues broken through life. In other cases again, the symptoms of concussion may gradually terminate in those of compression, and not unfrequently the reaction that comes on, passing beyond the bounds that are necessary for the re-establishment of the healthy functions of the brain, terminates in an inflammatory condition of this organ. 2nd. Compression of the brain is a common condition in injuries of the head, arising as it does from a great variety of causes; — from the pressure of a por- tion of bone, of blood extravasated, or pus formed within the cranium, or from a foreign body lodged there. In whatever way occasioned, however, the symp- toms, although presenting some differences, are tolerably constant. The patient lies in a state of coma, stupor or lethargy, being paralyzed more or less com- pletely, heavy, insensible, and drowsy, not answering when spoken to, or only when addressed in a loud voice and shaken perhaps at the same time. The breathing is carried on slowly and deeply, with a stertorous or snoring noise, and usually a peculiar blowing with the lips: one or both pupils are dilated; the pulse is full, often slow; the faeces passing involuntarily, and the urine not uncommonly being retained; the skin may be cool, but in many cases, on the contrary, is rather hot and perhaps perspiring;—not unfrequently this state of stupor alternates with paroxysms of delirium, or of local convulsive action. This state of coma may become complicated by the occurrence of symptoms of inflammation: and unless the cause that produces the compression be removed, it usually terminates speedily in death, the patient gradually sinking into more complete unconsciousness, and dying in an apoplectic condition. In other, but much rarer cases, the coma may continue almost an indefinite time, for many weeks or even months, until the compressing cause is removed, when the patient may recover consciousness, and the symptoms suddenly disappear. The diagnosis between concussion and coma has been sufficiently indicated in the preceding description of these two conditions as not to require special mention here. But, in many cases, it must be remembered that one state merges into the other, so that the symptoms are not so distinctly marked as has TRAUMATIC ENCEPHALITIS. 275 been indicated, and they are more especially obscured when associated with inflammatory action. 3rd. There is another condition of the brain, which, although differing com- pletely from concussion and compression, not unfrequently complicates these states, or may supervene independently of either, upon severe injury of the head. For want of a better term, this may be called irritation of the brain, and appears often to be connected with laceration of the cerebral substance. In it the patient lies in a state of semi-consciousness, unobservant of what is going on around him, unless spoken to or roused. He does not, however, lie quietly, but moans, tosses himself about, and not unfrequently twists and curls himself forwards, with his back bent, and the knees drawn up towards the chest. When spoken to, he answers in a peevish and irritable manner, if at all: frequently frowning and distorting his countenance, and being evidently pained at any attempt at fixing his attention. He is occasionally convulsed, and, at other times, is seized with fits of violent delirium, shouting and screaming. The pulse is usually slow and feeble, the skin cool, and the face pale, with a total absence of all signs of inflammation. This condition most generally terminates speedily in convulsions, coma, and death. 4th. Inflammation of the brain and its membranes from injury (traumatic encephalitis), is an affection of great frequency and corresponding importance. It is a condition that is specially apt to supervene in all injuries of the head; though the liability to it necessarily increases with the severity of the accident. This form of inflammation of the brain and its membranes may set in with great intensity in some cases, the symptoms of phrenitis being strongly marked; in other instances, again, it gradually creeps on in a slow and insidious manner, not attracting attention until it has given rise to some severe and ulterior con- sequences, as effusion or suppuration, when its symptoms become so mixed up with those of compression and of irritation, as to make the exact diagnosis of the patient's condition far from easy. The period at which inflammatory symp- toms of the brain may manifest themselves, after an injury of the head, varies greatly. In some instances they set in almost immediately on the patient reco- vering from the effects of the concussion ; the reaction from this state gradually assuming an inflammatory character. In other cases it is not until after the lapse of several days that inflammation declares itself; and, again, it sometimes happens that the inflammatory affection does not supervene for weeks or months; but then, occurring perhaps under the influence of comparatively trivial causes, may destroy the patient. After death, in cases of traumatic encephalitis, we usually find both the brain and its membranes affected. The arachnoid is, however, the structure that appears principally to suffer in these cases, being thickened, so as to become milky and semi-opaque. Adherent lymph of a greenish-yellow colour, and opaque purulent appearance, is seen covering one or both hemispheres of the brain, being deposited in largest quantity at the seat of injury, and not unfre- quently extending across and into its fissures, occupying especially the depres- sions about its base. The vascularity of the brain and its membranes is greatly increased, the arachnoid being reddened in patches, and the vessels of the pia mater becoming turgid and very numerous, forming a vascular net-work over the surface of the brain. The sinuses also are distended with blood, the cere- bral substance exhibits an increase in the quantity of red points, so as often to present a somewhat rosy hue; and the ventricles are filled with reddish semi- turbid serum, a large quantity of which is effused about the base of the brain. In some of the more advanced cases, inflammatory softening of the cerebral substance may occur. In considering the symptoms of traumatic encephalitis it is useless to endea- vor to make a distinction between the inflammation of the brain and that of its membranes; the two structures being always more or less implicated at the same 276 INJURIES OF THE HEAD. time. The most practical division of this disease following injury, is into the acute and the chronic, or sub-acute encephalitis. The acute encephalitis usually comes on within eight-and-forty hours of the infliction of the injury. The patient complains of severe, constant, and increas- ing pain in his head; the scalp is hot, the carotids beat forcibly, the pupils are contracted, the eyes intolerant of light, and the ears of noise; the pulse is full, vibrating, and bounding; and wakefulness, with delirium, usually of a violent character, speedily comes on. All the symptoms of severe constitutional pyrexia set in at the same time. By active and proper treatment this condition may gradually subside until the health is re-established, but more commonly the symptoms of inflammation merge into those of compression; the delirium becoming replaced partly or in whole by a state of stupor, from which the patient is roused with difficulty, the pupils gradually dilating, the breathing becoming heavy and stertorous, the pulse sometimes continuing with its former rapidity, at others becoming slow and oppressed. The skin is hot but clammy, the patient falls into a heavy, dull, unconscious state, which alternates with convulsive twitchings or jerkings, and occasional delirious outbreaks. As death approaches, the sphincters become relaxed, the pulse more feeble, the surface cooler, and the coma more intense and continuous, until the patient sinks from exhaustion and compression con- joined. In cases such as these, pus may be found upon the surface, or within the substance of the brain, in one case being diffused, in the other collected into a more or less distinctly circumscribed abscess. In other cases again, the symp- toms of compression appear to be induced by a thick layer of lymph lying upon the surface of the brain, or by a quantity of serous fluid being poured out into the ventricles and about the base. The chronic or sub-acute encephalitis is the most interesting and important variety of inflammation following injuries of the head. It may come on a few days after the infliction of the injury, or not until months have elapsed. It may arise from accidents that simply implicate the skull, as well as from those that extend their direct effects to the brain and its membranes. The patient in many cases has apparently recovered entirely from the accident, though in others it will be found that some one symptom indicative of the brooding mischief still continues, such as headache, or impairment of sight or of hearing Occasionally, the coming mischief is foreshadowed by an unusual degree of irritability of temper, by loss of mental vigor, or some other functional disturb- ance of the brain. In cases such as these the sub-acute encephalitis may sud- denly come on, ushered in perhaps by an aggravation of the persistent symptom, or by the occurrence of an epileptic fit. In other cases again, the symptoms set in suddenly without any warning, but usually with much intensity, and speedily prove fatal. The symptoms of the sub-acute encephalitis, when it has fairly set in, consist of those of inflammation, irritation, and compression of the brain conjoined; in some cases one, in other instances another, of the conditions appearing to predominate. The irritation and inflammation proceed from the increased vascular action; the compression from the effusion of serous fluid, of pus, or of lymph, exercising undue pressure upon the brain. The symptoms consist of pain in the head with heat of the scalp, and either dilatation or contraction of the pupils, occasionally one being dilated and the other contracted. Squinting, intolerance of light, delirium, moaning, or screaming, unconsciousness, with convulsive twitchings of the limbs and face, commonly occur with the ordinary symptomatic fever; and lastly, symptoms of coma, rapidly terminating in the patient's death. In the sub-acute encephalitis the same appearances are very generally found after death, as in the more acute form of the affection, but it commonly happens that it is the arachnoid membrane that is principally affected. So constantly ia TREATMENT OF CEREBRAL DISTURBANCE. 277 this the case, that some surgeons have proposed, and not altogether with injustice, to apply the term arachnitis, to this form of traumatic encephalitis, looking upon the inflammation of the arachnoid as the principal lesion. 5th. The formation of pus within the cranium is a point of much interest in these cases, and an endeavor has been made, especially by Pott, to lay down rules by which the occurrence of suppuration could be accurately determined. Thus it has been said, that if, during the continuance of encephalitis, fits of shivering come on, followed by the gradual supervention of coma, which slowly becomes more and more complete whilst the constitutional symptoms of inflam- mation do not subside; and if, at the same time, a puffy swelling forms upon the scalp, and the wound, if any, becomes pale and ceases to secrete, the peri- cranium separating from the bone, which is seen to be yellow and dry, an abscess will have formed under the skull; and further, that in all probability its seat will correspond to these changes in the scalp and pericranium. In many cases, doubtless, these signs have afforded proof of the existence of pus within the cranium. It but seldom happens, however, that the signs attending the formation of pus within the cranium occur in the distinct order and with the degree of precision above stated. In the great majority of cases the surgeon can only suspect the presence of pus by the symptoms of inflamma- tion terminating in paralysis or coma. But he cannot say with certainty that pus has formed, for the coma may arise from the pressure of other inflammatory effusions; but if the puffy swelling of the scalp or the separation of the peri- cranium occur, then he may feel himself justified in giving a more positive opinion as to its existence in some-situation within the cranial cavity, probably beneath or in the neighborhood of the part thus affected. In traumatic encephalitis secondary mischief often occurs in some of the thoracic or abdominal viscera, the lungs and liver being especially liable to be thus implicated. In the lungs, more particularly, it not unfrequently happens that congestion runs into some low form of pneumonia, and thus terminates the patient's existence. In the liver it has long been observed that abscesses are apt to form as a consequence of injuries of the head These usually occur as one of the more remote consequences of the injury, but yet there have been instances of an acute kind. Thus, Hennen has seen an abscess form in the liver of a temperate woman, thirty-six hours after the receipt of a blow upon the head. This connection between abscess of the liver and injury of the head is doubtless the result of pyemia, consequent on the suppuration of the diploe of the skull, the hepatic abscess being a metastatic deposit of pus consequent upon inflammation of the veins of the diploe and of the cerebral sinuses. The treatment of these various cerebral injuries, and their concomitant affec- tions, is one of the most important and difficult subjects that can arrest the surgeon's attention; the difficulty depending in a great measure on the various conditions that have just been described, not occurring in practice with that amount of distinctness and individuality by which their characters can alone be conveyed in description, but being associated together in such a way that the exact state of the patient cannot so readily be made out. There are few cases, indeed, in which practical tact and a nice discrimination and analysis of symp- toms are more required than in those now under consideration. It would, how- ever, be useless to attempt to describe the shades and modifications of treatment required in the management of the different groupings of these various forms of traumatic cerebral disturbance. We must therefore content ourselves with describing the treatment of each state broadly and separately, and leave the consideration of the varieties that so commonly present themselves in practice to the individual tact of the surgeon. In the treatment of concussion, the first great indication is to re-establish the depressed energies of the circulation and of the nervous system. In effecting this, we must, however, be careful not to over-stimulate the patient. The safest 278 INJURIES OF THE HEAD. practice is that which is applicable to the treatment of shock generally; — to wrap the patient up warmly in blankets, to put hot bottles around him, to em- ploy frictions to the surface, and when sufficiently recovered to allow him to swallow a small quantity of warm tea. Stimulants of all kinds should be avoided, as their after-effects may be injurious; unless the depression of the nervous energy is so great that reaction cannot be brought about without their agency. When reaction has come on, steps should be taken to prevent the occurrence of inflammatory mischief. With this view, if the concussion have been slight, it may be quite sufficient to purge the patient well, and to keep him quiet on a regulated diet for a few days, directing him carefully to avoid all alcoholic stimu- lants and mental exertion for some time. If the concussion have been more severe and if the symptoms of reaction have been accompanied by indications of continuous cerebral disturbance, or been followed by giddiness, headache, or confusion of thought, the safer plan will be to adopt immediate steps for the prevention of mischief. The patient should be bled generally or locally by leeches and cupping, freely purged, kept on a low diet, and, above all, remain quiet in bed for some days. Should impairment of the mental faculties or senses be left, the more prudent plan will be to have recourse to mild antiphlogistic treatment. Leeching, cup- ping, blistering, the introduction of a seton in the nape of the neck, purging, and more especially a mild mercurial course, with strict avoidance of all mental and bodily stimulation, is the plan of treatment that requires to be pursued. These cases must, however, be carefully watched, and kept under proper super- vision for some length of time, as serious symptoms are apt suddenly to declare themselves. When acute inflammation of the brain or its membranes has come on, at what- ever period after the injury, active treatment should be at once adopted. The head must be shaved, and an ice-bladder kept constantly applied. Bleeding from the arm, repeated as often as the pulse rises, as well as by cupping or leeches, must be had recourse to; the bowels should be freely opened, and rigid abstinence must be enjoined, the patient at the same time being confined to a darkened room, and removed from all causes of excitement. Calomel should then be administered, so as speedily to affect the mouth. As the disease assumes a chronic form, the same general plan of treatment, modified according to the intensity of the inflammatory affection, must be persevered in, the patient being kept for a length of time after the subsidence of all the symptoms in a state of complete quietude. The subacute encephalitis which occasionally follows injuries of the head, even at a remote period from their infliction, is a most dangerous and unman- ageable affection, being very apt to terminate in loss or impairment of sense, in diminution of intellectual power, or in local paralysis. Much of the difficulty in the treatment of these cases appears to arise from the fact that the inflammation is often of a low or erysipeloid character, consequently not admitting of active depletory measures. In these cases the best results are obtained by the proper administration of mercury and the employment of counter-irritants. The best mode of adminis- tering the mercury is to give calomel in small and repeated doses, half a grain or a grain every four or six hours until the gums are affected, and to keep them so by diminishing, but not leaving off the mineral. The repeated application of blisters over the shaven scalp is perhaps the most useful form of counter-irri- tant, to which, in more chronic cases, a seton in the neck may be added. So long as any symptoms of inflammatory action continue, this plan of treatment must be steadily kept up. The irritation of the brain, that occasionally occurs as the result of injury, is best treated by a moderate antiphlogistic plan, conjoined in some cases, and in TREATMENT OF CEREBRAL DISTURBANCE. 279 others followed, by the administration of opiates. This is the only consequence of injury of the head in which opiates can advantageously be given. They should never be administered if there be any heat of head and fulness of pulse, having a great tendency to excite cerebral inflammation. But in that peculiar train of symptoms that occasionally follows injuries of the head, and which I have described as irritation of the brain, and in which there is a total absence of all inflammatory action, I have occasionally found a full dose of laudanum quiet the delirium, and, by inducing sleep, restore the patient. This, however, requires great care. In all cases of coma from compression, the bowels should be freely opened by placing a drop of croton oil, mixed with a little mucilage, in the patient's meals, or by the use of oleaginous or terebinthinate enemata. The urine is to be drawn off twice in the twenty-four hours, the room darkened, and kept quiet, and ice or an evaporating lotion applied to the head. When symptoms of compression occur as the result of inflammation in the cranium, the treatment becomes surrounded by difficulties. If, notwithstand- ing antiphlogistic measures have been pushed to their full extent, rigors occur and coma supervenes, conjoined with a certain amount of continuous inflamma- tory action, the question always arises as to whether trephining should be had recourse to, on the supposition of matter having formed. In these cases two great difficulties present themselves; the first has reference to the existence of pus within the cranium, and the second to its situation. The question as to the actual existence of pus within the cranium, and the dependence of the symptoms of coma upon the compression exercised by the purulent deposit, is always a difficult one to determine. There are, as has already been stated, no absolute and unequivocal symptoms indicative of the formation of pus within the cranium, the same symptoms that accompany its formation being often closely simulated by the effusion of serum, or of puriform lymph, on the brain or its membranes. But although there may not be any symptom that is absolutely and unequivocally indicative of the formation of pus in this situation, it not unfrequently happens that the surgeon is enabled by the assemblage of general symptoms and local signs, to indicate its existence with considerable accuracy. In these cases, however, it is usually impossible to deter- mine the exact seat of the purulent deposit with sufficient precision to admit of its evacuation by the trephine; — whether the pus be between the cranium and the dura mater, between the layers of the arachnoid, underneath this membrane, between the cerebral convolutions, or deeply seated in the substance of the brain; whether it be situated under the seat of injury, and be there circum- scribed, or whether it be so extensively diffused as not to be capable of com- plete evacuation. That these difficulties are real, must be obvious to every prac- tical surgeon, and illustrative of them I may mention the two following cases, out of many that I have witnessed. A«man was admitted into University College Hospital with an extensive lace- rated wound of the scalp, denuding the pericranium. He continued free from all cerebral disturbance until the tenth day after the accident, when he com- plained of headache, had quick pulse, and a hot skin. At this time it was observed that the denuded pericranium had separated from the skull. He was treated by active antiphlogistic means, the symptoms subsiding, and went on favorably until the thirty-fourth day, when he suddenly became delirious and unconscious, though easily roused when spoken to loudly, and then answering rationally; his pulse fell to 48. He died on the thirty-ninth day, comatose. On examination after death, the pericranium was found detached at the seat of injury; under this the dura mater was thick, yellow, and opaque, but no pus was observable. On separating the hemispheres, however, a large abscess was found situated deeply in the anterior lobe on the injured side, and protruding into the median fissure. It contained about one ounce of pus. In such a case 280 INJURIES OF THE HEAD. as this, trephining would evidently have been useless; for although it was pro- bable that there was pus within the cranium, yet its seat could not have been diagnosed, and the abscess could never have been reached. Another case that was admitted into the Hospital, was that of a man who had received a large lacerated wound on the left side of the scalp in consequence of a fall. There was no injury to the bone, and the patient went on perfectly well until the seventy-seventh day, the wound cicatrizing. He was then sud- denly seized with hemiplegia of the right side, from which he recovered partially by being bled ; some twitching of the muscles, however, continuing. On the ninety-ninth day after the accident he became comatose, and was trephined by Mr. S. Cooper, but without relief, dying with symptoms of compression of the brain on the third day after the operation. On examination, thick yellow lymph was found, covering the whole of the upper surface of both hemispheres lying between the arachnoid and pia mater, and extending into the sulci between the convolutions. There was an abscess in the substance of the brain on the surface of the right hemisphere on the side opposite to the seat of injury. Here, though the symptoms were well marked, and the diagnosis as to the existence of pus correct, trephining was also useless, as the pus could not be evacuated. These cases serve to indicate the difficulties that surround any operation with the view of evacuating matter from within the cranium. When, however, the symptoms of inflammation have been interrupted by an attack of rigors followed by compression, with detachment of the pericranium, or a puffy swelling of the scalp, or by the separation of the pericranium, and the exposure of yellow and dry bone, there can be little doubt that the surgeon, though bearing in mind the extreme uncertainty of the case, might be justified in trephining at the seat of local change or of injury, in the hope of finding pus deposited beneath the cranium, and thus giving the patient his only chance of life. And should it not be met with there, and the dura mater appear bulging, and without pulsation, an incision might even be made through this membrane, in the hope that the abscess being circumscribed the escape of the pus might be facilitated. Should this attempt fail, there are few surgeons who would have the hardihood to follow the example of Dupuytren, who plunged a bistoury into the substance of the brain, and thus luckily relieved the patient of an abscess in this situation. But yet even though pus be found under the cranium, between it and the dura mater, and is evacuated, the encephalitis will probably lead on to the patient's death. Mr. P. Hewett states very justly that the suc- cessful termination of a case of trephining for matter between the skull and dura mater, is all but unknown to surgeons of the present day. INJURIES OF THE SCALP. Contusions of the scalp from blows are of common occurrence, and present some peculiarities that deserve attention. However severe the contusion may be, it seldom happens that the scalp sloughs. This is evidently owing to the great vascularity and consequent active vitality of the integuments of the head. In many cases a contusion in this situation is followed by considerable extrava- sation of blood, raising up the scalp into a soft semi-fluctuating tumor. It occasionally happens, especially in blows on the heads of children, that this extravasation gives rise to the supposition that fracture exists, owing to the edge of the contusion feeling hard, whilst the centre is soft, apparently from the depression of the subjacent bone. In some cases, indeed, this deceptive feeling will occur without any extravasation of blood under the scalp, the depressed centre being due to the compression of the scalp by the blow that has been inflicted upon it. This I have seen occasionally in children in whom the scalp is soft and somewhat spongy. The treatment of contusion of the scalp is very simple; the continuous appli- INJURIES OF THE SCALP. 281 cation of evaporating lotions being usually sufficient for the removal of all effu- sions. Under no circumstances should a puncture be made or the blood let out in any way. Contusions of the scalp in girls and young women have been known to be followed by severe neuralgic pains in the part struck. This affec- tion is extremely rebellious to treatment, but in two cases which I have seen, after lasting for a considerable length of time, these symptoms gradually disappeared; in such cases as these, incisions down to the bone are said to have sometimes been beneficial. It occasionally happens that bloody tumors of the scalp form in newly-born children, either from contusion of the head in consequence of the pressure to which it is subjected in its passage; or else by the bruising of obstetric instru- ments. These tumors, which are often of large size and fluctuating, are termed cephaloematomata. They may occur in two situations, either between the aponeurotic structures of the scalp and the pericranium, or between this membrane and the skull itself. The sub-aponeurotie cephalcematoma is by far the most common variety of the affection. It usually forms a large soft fluctuating tumor, situated upon one of the parietal eminences, and having a somewhat indurated circumference. These tumors may usually be made to subside in a few days by the use of discutient lotions. The sub-pericranial cephalcematoma is an injury of extremely rare occurrence. But Zeller, Valleiz, and others have determined its existence. It appears as a fluctuating tumor, without discoloration of the scalp, but with a hard elevated circle around it, and a soft depressed centre, almost communicating the sensation of a hole in the cranium. Pressure, however, gives rise to no cerebral symptoms, and enables the surgeon to feel the osseous lamina at the bottom of the depres- sion. These tumors are usually of small size, seldom larger than a walnut, and it not uncommenly happens that they are multiple. It is worthy of note, how- ever, that each tumor is always confined to a separate bone, never passing beyond the sutures, where the adhesions are the strongest between the pericranium and the subjacent osseous structure. This affection is said to be most frequently met with in children born in first confinements, and is more common in boys than in girls; according to Bouchard in the proportion of thirty-four to nine. The pathology of this affection has been studied by Valleix. This surgeon found that the pericranium was separated from the bone by an extravasation of blood, and that both bone and pericranium were covered with plastic matter, but otherwise healthy. He also found that the hard circle surrounding the depression was formed by a deposit of osseous and plastic matter which bounded the extravasation. This deposit was effected in such a way that on a transverse section being made, the inner wall was found nearly perpendicular, whilst the outer sloped down upon the cranium, thus giving a cratiform appearance to the margin of the tumor. The treatment of this affection must be conducted on precisely the same principles as that of the other forms of scalp extravasated. Wounds of the scalp are of very common occurrence, and are more serious than corresponding injuries elsewhere, especially so when occurring in persons about the middle period of life, and of unhealthy or broken constitutions. It is not only that these injuries are more likely to be followed by erysipelas than those of other parts of the body, but it is also to the great tendency to the pro- pagation of inflammatory mischief inwards to the encephalon, and to the com- plication of cerebral mischief so often accompanying comparatively slight injuries of the scalp, that these accidents owe much of their serious and often fatal cha- racter. But though there be this danger to life in scalp injuries, there is com- paratively little risk to the scalp itself; the abundant supply of blood it receives from closely subjacent arteries, and its consequent great vitality, is the reason why sloughing so seldom occurs, even though the part be much bruised and seriously lacerated. 282 INJURIES OF THE HEAD. The treatment of wounds of the scalp necessarily varies somewhat according to the nature of the injury. If this be a simple cut it will be sufficient, after shaving the parts around and cleansing its interior, to bring it together with a strip or two of adhesive plaster, and to dress it as lightly as possible. In these, as in all other cases of injury of the head, especial attention should be paid to the state of the brain, for however slight the external wound may be, serious cerebral mischief may have been occasioned; or, at all events, the same blow that has caused the cut in the scalp may have given rise to such functional de- rangement of the brain as may eventually lead to the worst forms of traumatic encephalitis. It more frequently happens that the scalp is bruised and lacerated as well as wounded, and very commonly that a large flap of integument is stripped oft' the cranium, and is thrown down over the face or ear, so as to denude the bones. In these cases, advantage is taken of the great vitality of the scalp. However extensively contused or lacerated this may be; however much it may be be- grimed with dirt; it is a golden rule in surgery not to cut any portion of it away, but after shaving the head and ligaturing any bleeding vessels, to wash and clean it thoroughly, and replace it in its proper position. Here it must be retained by the support of a few strips of plaster, or by the application of a suture or two at the points of greatest traction. If the edges do not come pro- perly together a piece of water-dressing must be applied, but the head must be kept cool, and as little bandaging and plastering had recourse to as possible. The patient should be freely purged and kept perfectly at rest on rather a low diet, any cerebral symptoms that occur being treated in accordance with the principles laid down in discussing traumatic affections of the brain. In this way union will very probably take place through the greater portion of the injured surface; should it not do so, however, or should any part slough, granulations spring up and reparative action goes on with surprising rapidity. If matter form beneath the aponeurosis of the occipito-frontalis muscle, bagging must be prevented by early counter-openings, and by the employment of compression in proper directions. The pus has a special tendency to gravitate into the upper eyelid whenever suppuration takes place beneath the frontal portion of the muscle, and here the counter-opening may be conveniently made. When the skull is extensively denuded in consequence of the scalp with the subjacent pericranium being stripped off, we must not necessarily expect that necrosis and exfoliation of the exposed bone will occur. In cases such as these, the flap must be laid down on the denuded osseous surface, to which it may pos- sibly contract adhesion. Should it not do so, however, the exposed portions of the cranium may inflame, plastic matter be thrown out, and thus granulations springing up, a covering be formed to the bone. INJURIES OF THE SKULL. Contusion of the cranial bones occurring in injuries of the head, especially complicated with wound of the scalp, is often a serious condition, if it be fol- lowed by suppuration in the diploe of the bone, and abscess between it and the dura mater, or even under this membrane. Fracture and other injuries of the bones of the skull possess great interest, not so much from the lesion of the bone itself, as from its frequent complication with injury of the brain and its membranes. This cerebral complication may either be produced by direct injury occasioned by the fragments of the fractured bone compressing or wounding the brain, or it may be the result of the same violence that occasions the fracture concussing or lacerating the brain. Fractures of the skull are invariably the result of external violence. This may act directly in breaking and splintering the part struck, the fissures often extending to a considerable distance and detaching large portions of the era- FRACTURE OF THE BASE OF THE SKULL. 283 nium; or, the violence may act in an indirect manner, producing the fracture either without being applied immediately to the cranium, or else at an opposite part of the skull to that which is struck. Thus the base of the skull may be fractured by the shock communicated to it when a person, falling from a height, strikes the ground heavily with his feet. The other variety of indirect fracture, that in which the solution of continuity occurs at a point of the cranium oppo- site to that which has been struck, is the fracture by " contre-coup." This kind of fracture has been described by some surgeons as of frequent occurrence, whilst it has been denied by others. There can, however, be no doubt that it does happen, though less commonly perhaps than is generally sup- posed. Every hospital surgeon must occasionally have seen unequivocal instances of it. For its occurrence several conditions are necessary. The skull must be struck over a large surface, as when a person falls with his head against the ground. If the blow alight on a thin portion of it, this will be directly fractured; but if a dense and strong part of the bone be struck, as the parietal eminence, or the lower part of the os frontis, the shock transmitted through the cranium generally will cause the thinnest and most brittle portions of the skull, though distant, to give way in preference to the stronger part on which the blow has immediately fallen. These fractures by contre-coup are most common at the base of the skull and are commonly much radiated. They are never depressed. An ordinary, simple, or undepressed fracture of the skull consists in a fissure, sometimes single, at other times starred, extending often to a considerable dis- tance through the bones, radiating sometimes across the skull, and at others completely detaching the upper from the lower, or the anterior from the poste- rior segment of the cranium. In some cases the fracture extends into one of the sutures, and in other instances, which, however, are very rare, the sutures are separated without any fracture. These injuries usually occur from direct violence, but are also the only forms of fracture that happen by contre-coup. A simple fracture, such as this, gives rise to no signs by which its diagnosis can be effected. If, however, the scalp covering the injured bone has been wounded, its existence may be ascertained by running the finger-nail, or the end of a probe, over the exposed surface of the bone, or by seeing a fissure into which the blood sinks. In these simple undepressed fractures no special treatment is required to the fracture itself, the surgeon's whole attention being directed to the concomitant injury that may have been inflicted on the brain or scalp. Active precautionary measures should be adopted without delay, with the view of guarding against the occurrence of inflammation of the brain and its membrane, even though no symptoms have as yet declared themselves. So soon as the patient has recovered from the con- cussion, his head should be shaved, the ice-bladder applied, and blood freely taken away from the arm; the bowels should be well opened, and the room kept cool and quiet. The employment of free and repeated bleeding is, however, of more service than any other means, and should never be omitted. The most serious, and indeed a very commonly fatal form of simple fracture of the skull, is that which extends through the base of the cranium. These injuries usually occur by falls from a height or blows upon the vertex or side of the head, producing a fracture which extends from the point struck across the base of the skull, often running through the petrous portion of the temporal bone or into the foramen ovale. They may also take place as the result of contre-coup, or by a person falling from a height on his head, and having the base of the skull broken in by the weight of the body projected against it. The great danger in these cases is the concomitant injury to the brain, either by its direct laceration or by the extravasation of blood upon it. Though most usually fatal, these injuries are not invariably so. Not only does it occasionally happen that patients with all those signs of fracture of the base of the skull, which 284 INJURIES OF THE HEAD. will immediately be described, are seen to make a complete recovery, but in the different museums, specimens illustrative of recovery after this accident may be met with. Thus, in the College of Surgeons' museum, there is the skull of a person who lived two years after a fracture at its base. The occurrence of fracture of the base of the skull is very commonly sus- pected when symptoms indicative of serious injury to the brain speedily follow a severe blow upon the head, owing to the greater liability to injury of those parts of the nervous centre that are most important to life, in these than in other fractures of the skull; the same violence that occasions the fracture injuring the contiguous portions of brain, or lacerating some of the large venous sinuses about the base of the skull, giving rise to abundant extravasation of blood. These symptoms are necessarily in the highest degree equivocal, and much anxiety has been evinced by surgeons to discover some special sign by which the occurrence of this particular fracture may be determined. There are two signs, the occurrence of which leads to strong presumptive evidence in favor of the existence of this kind of fracture. These are, 1st, the escape of blood, and 2ndly, of a serous fluid from the ears, and occasionally from other parts in connection with the base of the skull. The occurrence of bleeding from the ears after an injury of the head cannot by itself be considered a sign of much importance, as it may arise from any violence by which the tympanum is ruptured without the skull being necessarily fractured. If, however, the hemorrhage be considerable and continuous, and more especially if it be associated with other symptoms indicative of serious mischief within the head, and if it have been occasioned by a degree of violence sufficient to fracture the skull, we may look upon its supervention as a strong presumption that the petrous portion of the temporal bone has been fractured, and perhaps one of the venous sinuses in its neighborhood torn. Bleeding from the nose may of course arise from any injury applied to this organ without the skull being implicated; but yet in some cases of fracture of the skull the hemorrhage proceeds from the interior of the cranium, the blood escaping through a fissure in the roof of the nasal fossae. In a patient of mine who died five weeks after an injury of the head, accompanied by much bleeding from the nose, a fracture by a contre-coup was found extending across one orbital plate of the frontal bone, and separating its articulation with the ethmoid. In this case the nature of the injury was suspected from the fact of the nose itself having been uninjured by the blow, although the hemorrhage from it was very considerable and continuous. The discharge of a thin watery fluid from the interior of the cranium is of rare occurrence, but when it happens may be considered as pathognomonic of fracture of the base of the skull. Indeed it is the most certain sign of this injury that we possess. This discharge usually takes place through the ear: but it may occur from the nose, of which I have seen one instance, and Robert mentions another. Still more rarely it takes place from a wound in the scalp communicating with the fracture, percolating through this, and so being poured out externally. The only case of this kind with which I am acquainted is one which was communicated to me by one of the pupils of the College, as occur- ring at the Penrhyn Infirmary a few years ago. In this case a boy received a wound on the back of the head, with depressed and comminuted fracture of the skull. On the nineteenth day after the receipt of the injury a large quantity of serous fluid began to discharge through the wound, and continued to do so profusely until his death from coma four days later. There would consequently appear to be three situations: the ear, the nose, and a wound on the head, from which this discharge has been observed. It is an exceedingly valuable though most serious sign; and Robert, who has investi- gated this phenomenon with much closeness, states, that the cases in which it happens always terminate fatally. This, however, is an error; for at least one FRACTURE OF THE BASE OF THE SKULL. 285 case has occurred at the University College Hospital, in which the patient recovered, although a large quantity of fluid was discharged from the ear. It is usually associated with symptoms indicative of serious injury to the base of the brain, but to this there are also exceptions, for I have seen it take place in cases of injury of the head, unaccompanied by any severe cerebral symptoms. Most generally it occurs in young people. Robert says that it does so invari- ably, but in one of the cases that I have witnessed the patient was fifty-eight years of age. The quantity of fluid that is thus discharged is always very considerable, the pillow usually becoming soaked by it, and thus first attracting attention to it. It is often necessary to keep a piece of sponge or a pledget of lint against the ear, in order to prevent the fluid wetting the patient, as it trickles out, and if a cup be so placed as to collect it, an ounce or two will speedily accumulate. Laugier states that he has seen a tumblerful discharged in a short time, and as much as twenty ounces have been known to be poured out in three days. The flow is usually continuous for several days, and then ceases. It is remarkable that the hearing does not always appear to be destroyed in the ear from which the discharge takes place. The nature and the source of this discharge have been particularly investigated by Laugier, Chassaignac, Robert, and Guthrie. Its physical and chemical characters are those of a perfectly clear, limpid, and watery fluid, containing a considerable quantity of the chloride of sodium, with a little albumen in solu- tion. It is not coagulable by heat or nitric acid. The source of this discharge has not as yet been investigated with all the attention that its importance requires. Laugier believed it to be the serum of the blood filtering through a crack in the petrous portion of the temporal bone, and so out through the ruptured tympanum. This explanation, however, is evi- dently not correct, for not only is blood extravasated in the living body incapable of this species of rapid and complete filtration, but the chemical composition of the fluid, which differs altogether from that of the serum of the blood, in con- taining a mere trace of albumen and double the quantity of chloride of sodium, is incompatible with this supposition. By others it has been supposed that the fluid was furnished by the internal ear, being a continuous discharge of the liquor cotunnii, but its large quantity, and, above all, the fact of its occasionally escaping through the nose, establishes the fallacy of this explanation. Again, it has been supposed, but without sufficient evidence, that the cavity of the arachnoid furnished this secretion. I think with Robert that there can be little doubt that this discharge consists of the cerebro-spinal fluid, for not only does it resemble in appearance and chemical composition this liquid, but there is no other source within the cranium that can yield with equal rapidity so large a quantity of fluid; experiment having shown that the cerebro-spinal liquid is rapidly reproduced after its evacuation. In order that this be discharged, it is necessary that the membranes of the brain be ruptured opposite the outlet by which it is poured forth. This has actually been ascertained to be the case in carefully conducted dissections of injuries of the head in which this symptom has occurred. When it is discharged through the ear it is not improbable, as Berard has remarked, that the laceration extends through the cul-de-sac of the arachnoid, which is prolonged around the auditory nerve in the internal audi- tory canal. When it is poured out through the nose, it has probably been by the fracture extending through the sphenoidal sinuses. The treatment of fractures of the base of the skull must be conducted on those general principles that guide us in the management of simple fractures; no special means can be had recourse to, and in the great majority of cases a fatal termination speedily ensues. It occasionally though very rarely happens that in consequence of a blow a portion of the cranium is depressed without being fractured, and even without 286 INJURIES OF THE HEAD. any serious symptoms occurring. Thus Green mentions a case in which the bowl of a dessert-spoon might be laid in the hollow produced in the skull by a blow, and no symptoms resulted. These depressions without fracture can, how- ever, only occur in children whose crania are soft and yielding. In adults they cannot happen without the occurrence of partial or incomplete fracture. It must be borne in mind, however, that the apparent depression produced by an extravasation under the scalp may simulate this injury very closely, and a very experienced surgeon may sometimes under these circumstances be deceived, and be induced to cut down on a suspected fracture when in reality none exists. Depressed fractures of the skull may either be simple, without wound of the scalp, compound, or comminuted. In the majority of cases, whether the frac- ture be simple or compound, there is comminution of the injured portion of bone; the fragments being perhaps driven into the brain. Depressed fractures of the skull present many varieties; sometimes, though very rarely, the external table alone is depressed. This is especially the case over the frontal sinuses, where it may be broken in, as I have seen happen from the kick of a horse, without the inner table being splintered, or any bad conse- quences ensuing. Much more commonly, however, the inner table is driven in with comparatively little injury to the outer one; it has, indeed, been stated that a portion of the inner table may be depressed without there being any frac- ture of the external one; this, however, can scarcely occur, though it may happen with but a very trifling fissure of the outer table. In all ordinary depressed fractures the internal table is splintered to a greater extent than the external one. This is especially the case when the fracture is the result of gun-shot injury, or when it has been occasioned by blows with a pointed weapon, as the end of a pick, or a large nail, or the sharp angle of a brick. In these fractures, which constitute the dangerous variety termed punc- tured, the outer table may be merely perforated or fissured, whilst the inner one is extensively splintered. This splintering of the inner lamina of the skull to a greater extent than the outer one has attracted much attention, being of con- siderable practical moment, and is usually said to be owing to its being more brittle than the external table. This, however, I do not consider to be the only cause. I should rather attribute it to the direction of the fracturing force from without inwards, causing a certain loss of momentum in passing through the outer table; and that thus the inner table is splintered more widely than the outer one, for the same reason that the aperture of exit made by a bullet is larger than that of entry. If this be the Fig. 130. true explanation, the reverse ought to hold good if the force be applied in the opposite direction. It is very seldom that we have an opportunity of examining such a case; but a few years ago a man was brought to the hospital who had committed suicide by discharging a pistol into his mouth and upwards through the brain. The bullet had perforated the palate and passed out at the upper part of the cra- nium, near the vertex (fig. 130). On examining the state of the bones, it was found that the outer table of the skull was splintered to a considerably greater extent than the inner one, showing clearly the influence of the direction of the fracturing force. I have since found by experiment on the dead body, that this is most generally the case when the blow is struck from the inside of the skull outwards. It occasionally happens as the result of sabre or hatchet cuts on the head, that a kind of longitudinal punctured fracture occurs, in which the outer table TREATMENT OF DEPRESSED FRACTURE. 287 is merely notched, whilst the inner one is splintered along the whole line of blow. In other cases, again, a portion of the cranium is completely sliced off, hanging down in a flap of the scalp, and exposing the brain or its membranes. The symptoms of a depressed fracture of the skull are of two kinds : those that are dependent upon the injury to the bone, and those that result from the con- comitant compression or laceration of the brain. When the scalp is not wounded, the depression may sometimes be felt; but very commonly it is masked by extravasation of blood about it, and the surgeon is only led to suspect its existence by the continuance of symptoms of compres- sion from the time of the injury. In all cases of doubt when these symptoms exist, an incision should be made through the scalp at the seat of injury, and the state of the skull examined. When there is a wound in the scalp communi- cating with the fracture, the surgeon detects at once the existence of depression and comminution by examining the bone with his finger through the wound. Although symptoms of compression almost invariably exist from the first in cases of depressed fracture, yet it occasionally happens that no cerebral disturbance comes on for some days, even though the injury done be very extensive. A man, twenty-four years of age, was admitted into University College Hospital under Mr. Morton. He had been struck on the forehead with the sharp edge of a quoit. The frontal bone was extensively*comminuted, twelve fragments being removed, and the dura mater being exposed to a. considerable extent; yet no bad symptoms occurred until the ninth day, when inflammation of the brain and its membranes set in, and he speedily died. In other cases again, more especially in children and young persons, in whom the bones are soft and yielding, depression with fracture may exist to a con- siderable extent, and no symptom whatever of compression be produced at the time or at any subsequent period,—the patient living with a portion of his skull permanently beaten in. The great danger in these cases of depressed and comminuted fracture arises, however, not only from the compression of the brain, but from the rapidity with which inflammation is set up in consequence of the sharp fragments wounding and irritating the membranes and brain. Indeed, a wound of the dura mater, however slight, is a most dangerous complication, and one that is not often recovered from. It is not, however, necessarily fatal; I have lately had a case under my care, in which, although this occurrence had taken place in conse- quence of depressed fracture, the patient made a good recovery. This is more especially the case in those injuries in which the inner table is extensively splin- tered, as in the different forms of punctured fracture. In these cases there may be no signs of compression, but inflammation speedily sets in, and certainly proves fatal if the causes of irritation, the sharp spiculae, be allowed to remain in contact with the dura mater. This membrane becomes sloughy and coated with a thick deposit of plastic matter, whilst the usual evidences of encephalitis are found in the other membranes and the brain. The treatment of a depressed and comminuted fracture of the skull varies according to the nature and extent of the accident. If there be no wound in the scalp, but the occurrence of symptoms of com- pression and the existence of some irregularity of the cranium at the seat of injury lead the surgeon to suspect a depressed fracture, he should make a crucial or T-shaped incision down upon the part in order to examine the bone, and if this be found depressed to elevate or remove it. If the scalp be already wounded all that need be done to ascertain the nature of the fracture, is to pass the finger into the wound and thus examine the bone. If any fragments be found lying loose they should be picked out, as their pre- sence can only excite injurious irritation; any bone that is driven below its level must be raised, and, if completely detached, removed. In order to raise these depressed portions of bone, it is in many cases only 288 INJURIES OF THE HEAD. necessary to introduce the point of an elevator underneath the fragment, and using the instrument as a lever, elevate it into position. If there be not an aperture sufficiently large for the introduction of the elevator, one must be made by sawing out an angle of bone at a convenient spot by means of a Hey's saw or bone forceps. In this way sufficient spac* may usually be gained without the necessity of applying the trephine. If, however, the inner table be splin- tered to a considerable extent, or, if there be no convenient angle that can be removed, the trephine must be applied in such a way that at least half its circle is situated upon the edge that overhangs the depressed bone; the surgeon saw- ing out by means of this instrument a portion of the undepressed cranium, in order that he may more conveniently get at the fragment. After a half circle of bone has been removed in this way, the depressed splinters may be taken out; a Hey's saw still being occasionally required before the whole can be re- moved ; the flaps of scalp should then be laid down, a suture or two applied, and water-dressing put over the wound. Rigorous antiphlogistic treatment must then be adopted with the view of preventing or removing the inflammatory symptoms which set in. In all cases that partake of the nature of a punctured fracture, those in which there is but slight injury of the external table, but considerable splintering and depression of the inner one, the trephine must be applied on different principles to those that guide us in its use in ordinary depressed fractures. In the punc- tured fracture it is applied, not to remove symptoms of compression which, in all probability, may not exist; but with the view of preventing inflammation, which would to a certainty be set up if the splinters of the inner table were allowed to continue irritating the membranes and brain. Hence it is a rule in surgery, in all cases of punctured fracture, to apply the trephine at once, so as to prevent those injurious after-consequences, which must otherwise necessarily result. In these cases a trephine with a large crown should be used, and the circle of injured bone itself must be sawn out. Should, however, the use of the trephine have been delayed in these cases until inflammatory action have been set up, the instrument may still be applied with advantage. Some years ago, a boy was admitted into University College Hospital, on the sixteenth day after having been struck on the side of the head by a large nail, which projected from a door that fell upon him. No symptoms of any kind had occurred until the eleventh day after the accident, when he became dull and lost his appetite; on the sixteenth day, that of his admission, he had suddenly become drowsy and delirious, but answered rationally when spoken to, and complained of pain in the head. The pupils were dilated, the skin hot, and the pulse quick. On examination a small round aperture from which some fetid pus exuded was discovered on the right parietal eminence. On introducing a probe, which the hole just admitted, some rough bone could be felt. Mr. S. Cooper immediately trephined the boy, removing a circle of bone including the small aperture The inner table corresponding to this was found splintered to some extent, and the dura mater was seen to be thickened and inflamed, but the patient recovered without a bad symptom. In those rare cases in which there is a depressed fracture, without symptoms of compression, or even a wound of the scalp, the line of practice is somewhat unsettled, as to whether the depressed portion of bone should be left where it is, or an attempt be made to elevate it. Sir A. Cooper, Abernethy, and Du- puytren advise that, if it give rise to no symptoms of compression, it is better not to interfere with it; and there are several cases on record of patients who have recovered in whom this course was adopted, the depression continuing permanent. I am acquainted with a gentleman upwards of fifty years of age who has a depression in the parietal bone as large as the bowl of a table spoon, the result of a fracture from a fall from a horse when a lad, and from which no inconvenience has resulted. I think, however, that this expectant practice WOUNDS OF THE BRAIN. 289 should not be followed too implicitly, but that we must be guided by the cir- cumstances of the particular case. If the depression be pretty uniform, of inconsiderable depth, and occupy some extent of cranium, it may be better doubtless to follow the practice of these great surgeons, and to wait for symp- toms of compression manifesting themselves before we interfere. If, however, the depression be sharp, and comparatively small in extent, we may reasonably suspect the existence of considerable splintering of the inner table; and here the safer plan would be, even in the absence of all symptoms of compression, to trephine for the same reason that we do so in punctured fracture — the pre- vention of inflammatory irritation. The sooner this is done the better. Danger does not arise from early opera- tions, but from delay. The presence of depressed and spiculated fragments pressing into the dura mater must infallibly and speedily induce encephalitis. I have several times trephined under such circumstances as these with success, and have never had occasion to regret doing so. Even though several days have elapsed and inflammation has set in, the proper treatment will be to remove the depressed and splintered bone, and thus give the patient his only chance, a slender one, it is true, of recovery. Under such adverse circumstances the patient may, however, be saved. A man was admitted under Mr. Liston for a long depressed fracture on the side of the head, received by the blow of a brickbat; though no sign of com- pression existed, yet symptoms of cerebral inflammation were speedily set up, and Mr. Liston trephined him on the fourth day after the accident; the man, who was perfectly conscious, walking into the operating theatre. A consider- able splintering of the inner table was found, the fragments of which were removed. The dura mater having been punctured by one of the spiculae of bone, diffuse suppuration of the membranes of the brain set in, and the patient died in a few days. In this case, however, the necessity for early trephining was clearly indicated, notwithstanding the absence of any symptom of compression. When a depressed fracture of the skull is complicated with a fracture or other injury of the spinal column, it is sometimes difficult to determine how much of the symptoms may be due to one accident, and what proportion to the other. In such a case as this, however, we should, I think, treat the depressed fracture irrespective of the vertebral injury, thus giving the patient a chance of recovery, of prolongation of life, or, at least, of return of consciousness before death. A man was admitted under my care into the hospital, with depressed fracture of the left parietal bone, and injury of the cervical spine, the precise nature of which could not be accurately determined. He was in a state of complete coma and paralysis. I trephined the skull and elevated the depressed portion of bone; he recovered his consciousness to a great degree, but died in a few days, apparently from the injury to the spine. On examination after death we found a fracture of the fifth cervical vertebra. WOUNDS OF THE BRAIN AND ITS MEMBRANES. Wounds of the brain and its membranes are frequent in injuries of the head, and constitute one of the most important complications of these accidents. The extent of injury inflicted upon the cerebral substance has wide limits, from slight laceration without exposure, to denudation of the brain, disintegration, and escape of large portions of its pulp. Injury to the brain may be occasioned in various ways. The simplest form is that, perhaps, which is not unfrequently met with in undepressed fracture of the skull, and sometimes happens without fracture, from simple concussion or commotion of the head, laceration of the cerebral substance occurring either under the seat of injury, or more frequently at a distant or opposite point, by a kind of contre-coup. This laceration of the brain by contre-coup is by no means 19 290 INJURIES OF THE HEAD. of unfrequent occurrence. I have seen many striking instances of it, and have found it to be one of the commonest causes of death in simple fractures of the skull. Laceration of the brain by contre-coup is attended by much extravasation of blood; and after death the brain substance is found mixed up with coagula, and forming a soft, pulpy, bloody mass. This accident may occur without any fracture of the skull, or external sign of serious injury, and usually results from falls upon the back or side of the head, often from an inconsiderable height, as in a person slipping suddenly up in frosty weather and striking his head on the pavement; when the anterior or opposite portions of the hemispheres of the brain to that struck will be found in the condition just described. The brain and its membranes are often lacerated by the sharp spiculae of a depressed fracture, which may penetrate to a considerable depth in its substance. And, lastly, the injury may be occasioned by foreign bodies, such as bullets traversing or lodging in the head, or by stabs and punctures through the thinner portions of the skull, especially the orbital plate of the frontal bone. In this way pieces of stick, tobacco-pipe, the point of a knife, or a scissor-blade, may puncture the anterior part of the brain. The symptoms of wound or laceration of the brain vary greatly according to the age of the patient, the seat of injury, and other conditions, which cannot very readily be determined. If the injury implicate those portions of the nervous centre at the base of the brain, the integrity of which is necessary for the proper maintenance of the respiratory act, immediate death must necessarily ensue. If, however, portions of this organ that are less vital, as the anterior lobes and upper part of the hemispheres, are injured, but very slight symptoms may occur; and in some cases, indeed, there is no positive indication by which this injury of the cerebral substance can be determined, except by its exposure and escape through the external wound. Hence it is that even the worst injuries of the head are rarely immediately fatal, the patient being seldom killed outright unless the medulla oblongata be wounded. Children, especially, have been known to bear extensive injuries of the brain, and even the loss of a con- siderable quantity of cerebral matter without any very serious effects, either immediate, or remote; and it is by no means of uncommon occurrence to see them live for several days with an extent of injury to the brain, that would rapidly have proved fatal to an adult. Twitchings of the muscles and epilepti- form fits are commonly met with when the brain is lacerated, and these compli- cating stertor, or alternating with it, indicate the nature of the mischief. Foreign bodies even of large size and considerable weight have been lodged for a_ considerable time within the cranium, in contact with the brain, without occasioning death. Thus Hennen states that he has seen five cases in which bullets were lodged within the cranium, that did not prove immediately fatal. Dr. Cunningham relates the case of a boy who lived for twenty-four days with the breech of a pistol, weighing nine drachms, lying on the tentorium, and resting against the occipital bone. Dr. O'Callaghan has recorded the remarkable case of an officer who lived for about seven years with the breech of a fowling- piece, weighing three ounces, lodged in the forehead; the right hemisphere of the brain resting on the flat part, from which it was only separated by false membrane. [Perhaps the most remarkable case on record of severe injury of the head, terminating in recovery, is the one reported by Professor Bigelow, of Harvard University (see American Journal of the Medical Sciences for July, 1850), in which, by the premature explosion of a blast, a tamping-iron, three feet seven inches in length, one and a quarter inches in diameter, and weighing thirteen and a quarter pounds, traversed the skull. « The wound thus received was oblique, traversing the cranium in a straight line from the angle of the lower jaw on one side to the centre of the frontal bone above, near the sagittal suture, WOUNDS OF THE BRAIN. — HERNIA CEREBRI. 291 where the missile emerged; and the iron thus forcibly thrown into the air was picked up at a distance of some rods from the patient, smeared with brains and blood. From this extraordinary lesion, the patient has quite recovered in his faculties of body and mind, with the loss only of the sight of the injured eye."] From the great variety of effects produced by these injuries, it must be evident that there can be no one set of symptoms indicative of wound of the brain, provided there be no external wound through which the condition of the cerebral substance can be ascertained. In those cases in which this does not exist, we can at most only suspect laceration, if we find that the ordinary symptoms of compression or concussion are associated with signs that do not usually occur in those conditions when uncomplicated; such as the contraction of one pupil, the dilatation of the other, and perhaps an alternation of these states with twitchings'of the limbs, hemiplegia of one side, or paralysis of an arm, and of the opposite leg, with perhaps involuntary spasmodic movements of the other members. These irregular symptoms, when accompanied by much coldness of the surface, slowness of pulse, and depression of vital power, may generally be looked upon as indicative of cerebral laceration. Wounds of the dura mater are always liable to be followed by symptoms of the most serious character, and are seldom recovered from; diffuse meningitis, the formation of pus within the cranium usually occurring and speedily ter- minating the patient's existence. I have, however, seen recovery follow this accident. Wounds of the brain may prove fatal, either at once by the injury of the respiratory tract; in the course of a few hours, by the continuance of shock, and by the extravasation of blood within the cranium; at a later period, by the occurrence of encephalitis and its consequences; or more remotely still, by the supervention of paralysis and other ulterior effects of injury of the nervous system. In the treatment of injuries of the brain, little can be done after the system has rallied from the shock, beyond attention to strict antiphlogistic treatment, though this need not be of a very active kind. In these cases, indeed, as much should be left to nature as possible, the surgeon merely removing all sources of irritation and excitement from his patient, and applying simple local dressings. If any foreign body be lodged within the cranium, it must of course be removed, if possible. This may be done if it be situated near the external wound, or fixed in the bones, but if it have penetrated deeply into the sub- stance of the brain, and have got beyond the limits of the external wound, it would be perhaps more dangerous to trephine the skull on the chance of reaching it, or in any other way to go in search of it, than to leave it where it is. Fungus or hernia cerebri.—In those cases in which a laceration of the brain and dura mater communicates with a fracture of the skull, it is occa- sionally found, more particularly in children, that a bloody, fungous-looking mass of cerebral matter protrudes from the wound. This tumor increases pretty rapidly, pulsates synchronously with the brain, and may shortly attain the size of a hen's egg, or even become larger. It is composed of softened and disinte- grated cerebral matter, infiltrated with lymph and blood. This softening of the brain, with red discoloration of its substance, extends for some little distance under the base of the tumor. The mental condition of the patient laboring under this affection is in many cases not much disturbed at first, there being merely some degree of cerebral irritation. Speedily, however, stupor comes on, and death eventually occurs from coma. The treatment of this complication of fractures of the skull is commonly extremely unsatisfactory. If the tumor be shaved off, as usually recommended, it generally sprouts again until the patient is destroyed by irritation and coma 292 INJURIES OF THE HEAD. conjoined. In some fortunate cases, however, the removal of the tumor is not followed by its reproduction. All that can be done is to slice off the growth on a level with the brain ; to apply a pledget of wet lint, and a compress and bandage over the part, thus allowing it to granulate and the wound to cicatrize. EXTRAVASATION OF BLOOD WITHIN THE SKULL Commonly occurs in all injuries of the head accompanied by laceration of the brain, and in many of those in which the skull is fractured without that organ being injured. Indeed, when we reflect on the great vascularity of the parts within the cranium, the large sinuses, the numerous arteries, that ramify both within the bones and at the base of the brain, and the close vascular network extended over the surface of this organ, we can easily understand that extrava- sation of blood is one of the most frequent complications of these injuries and a common cause of death, when they terminate fatally at an early period after their occurrence. Extravasation of blood within the cranium may take place either from the fracture tearing across one of the meningeal arteries distributed on the inside of the skull, or by a fragment of bone wounding a sinus, or the vascular network on the surface of the brain, or it may proceed from laceration of this organ breaking down its capillary structure. In other cases again, as in gun-shot wounds, the hemorrhage may occur as a consequence of the wound of the vessels by the bullet or other foreign body. The extravasation may occur in four situations. 1st. Between the dura mater and the skull, where it is most commonly met with; 2d. Within the cavity of the arachnoid; 3d. Upon the surface of the brain; or, 4th, within its substance and its ventricles. It is usually most considerable when poured out upon the dura mater, or within the cavity of the arachnoid at the base of the brain. It is in smallest quantity immediately on the surface of that organ, or within its substance. It is, however, seldom found in the latter situation as the result of violence, without being also met with more superficially. The quantity effused in any one case seldom exceeds four ounces; and when in large quantity, such as this, it usually proceeds from rupture of the meningeal artery. Extravasation of blood is one of the most frequent causes of death in injuries of the head, by inducing pressure on the brain, and coma. The blood that is extravasated usually coagulates into a firm granular clot. There can be no doubt, however, that extravasation of blood into the membranes of the brain frequently occurs without being attended by fatal consequences. The blood that is so extravasated may undergo various changes. It would appear that the extravasated blood may 1st, be absorbed entirely; 2d, that the serous portions and coloring matter may be removed, leaving a fibrinous buff-colored clot, which may eventually become organized; and 3d, the exterior of the clot may become consolidated, whilst the interior contains fluid and disintegrated blood. The symptoms of extravasation are often by no means very clear; being those of compression associated in the early stages of the case with symptoms indi- cative of laceration of the brain, and, at a later period, with those of encephalitis. Putting out of consideration, however, these complications, the more special symptoms of compression from extravasated blood may occur in two ways. In the first variety there are three distinct stages, viz. concussion, a return and some continuance of consciousness, and then coma gradually supervening. The patient is concussed or stunned, as usual after the receipt of a blow on the head; from this he quickly rallies, and then symptoms of compression set in, and gradually increase in intensity. He becomes drowsy and dull, with a slow and laboring pulse, dilated and sluggish pupils, and a tendency to slow respira- tion ; as the compression increases, complete stupor at length comes on, with EXTRAVASATION OF BLOOD. 293 stertor in breathing, and there is either general paralysis, or hemiplegia of the side opposite to the seat of injury. When the symptoms run this regular course it is probable that the extrava- sation results from injury of one of the meningeal arteries, or large venous sinuses; that the extravasation is confined to the membranes of the brain, and that there is no laceration of the substance of this organ. This may be termed the meningeal extravasation ; and most commonly occurs from rupture of the middle meningeal artery, which, from its situation in a deep canal in the parietal bone, is peculiarly apt to be torn in injuries of the side of the skull. More commonly, however, it happens that the patient never recovers his con- sciousness after having been stunned, the symptoms of concussion speedily passing into those of compression. In these cases the paralysis is commonly incomplete and associated with twitchings of the limbs or convulsive movements of the body generally, and much restlessness with incoherent muttering: there is sometimes contraction, at others dilatation of the pupils, and it occasionally happens that squinting is observed. It is especially when there are convulsions, that the pupils are observed to be in different conditions; and I have most fre- quently noticed the pupil dilated on the side that is most convulsed. In these cases the extravasation is probably connected with, and dependent on, laceration or disorganization of a portion of the brain, and may consequently be termed the cerebral extravasation. The diagnosis of these two forms of extravasation from one another is im- portant, as it is only in the meningeal that any operative procedure can be suc- cessfully undertaken, and it may usually readily be effected by attention to the symptoms just detailed. The diagnosis of the compression from extravasation, and that from depressed bone or inflammatory effusions within the cranium, is easily made. In the case of the depressed fracture, we have symptoms of compression continuing uninter- ruptedly from the very first, and proper examination of the cranium will always lead to the detection of the injured bone. When inflammatory effusions, whe- ther of pus, lymph, or serum, exercise undue pressure upon the brain, we find that the signs of compression have been preceded by symptoms of cerebral inflammation, and that they are accompanied by a good deal of pyrexia, by quick pulse and hot skin; the character of the scalp wound likewise, and the separation of the dura mater when pus is effused, enable us to distinguish this condition from those cases in which the pressure is the result of extravasated blood. From apoplexy, the diagnosis is not always easily made, more particularly when there is no evidence that the head has been injured. A man was brought to University College Hospital in a state of profound coma, in which condition he had been found lying in the street. There was no evidence of injury about the head, beyond a bruise, which had probably been received when he fell. The case, which was supposed to be one of apoplexy, and treated accordingly, proved fatal in a few hours. On examination after death the skull was found fractured, but not depressed. On the opposite side to the bruise and fracture, a coagulum weighing nearly four ounces and compressing the brain, lay between the dura mater and bone. In such a case as this, it is evident that the history can alone afford a clue to its true nature. Even when the head has been injured it is not always easy. A man was admitted under my care, comatose. A fortnight previously he had been struck on the left side of the head behind the ear. He was stunned, bled freely from the left ear, but then got tolerably well, and went about his avocations as usual until the day before his admission, when he became suddenly comatose. There was stertor, quick pulse, some heat of head, the right pupil natural, the left, contracted. He was treated antiphlogistically, but died on the third day. On examination, a fracture on the left side of the skull was found extending into the left internal meatus; on the 294 INJURIES OF THE HEAD. right side of the head immediately opposite the fracture and the seat of injury, a large coagulum was found in the cavity of the arachnoid, with some serous exudation about it. Here was a meningeal extravasation, the result of contre- coup, existing without symptoms for fourteen days, and then proving rather sud- denly fatal by the supervention of inflammation. From the insensibility of drunkenness the coma resulting from injuries of the head may usually be distinguished, by the absence of local mischief, by the smell of the breath, and by the face of the drunkard being flushed and turgid instead of pale, as in a person who is suffering from the effects of a severe injury. When a drunken person has met with an injury of the head and is insensible, he should always be carefully watched, however slight the injury may appear to be, until time has elapsed sufficient for him to recover from his drunken fit, as it is impossible to say whether the stupor be the result of intoxi- cation, or of mischief within the cranium, and I have known cases sent away from hospitals as drunk, when in reality the stupor was occasioned by depressed bone. The treatment of extravasation of blood may be conducted on two principles, either by means of general and local antiphlogistic measures, having for their object the arrest of further hemorrhage, the promotion of absorption, and the subdual of inflammatory action; or else by the application of the trephine, with the view of allowing the escape of the effused blood. The line of treatment to be adopted should, I think, have reference to the character of the symptoms. When these indicate the cerebral form of extrava- sation, trephining can be of little service, and we must content ourselves with general antiphlogistics; but when the extravasation seems to be meningeal, then an attempt might be successfully made to evacuate the extravasated blood. Although the operation of trephining in cases of extravasation was formerly much in vogue, it is seldom had recourse to by modern surgeons, and is only proper in the meningeal form of extravasation. It is very true that if it could be ascertained without doubt that the extravasation is not only of the meningeal character, but that it is so situated that the blood may be removed through the trephine aperture, and that there were no other serious injury to the brain or skull, the operation should at once be performed. And doubtless the case occa- sionally happens in which, from the situation of the blow, and perhaps of a capillary fissure over the course of the middle meningeal artery, the gradual supervention of signs of compression, after an interval of consciousness, and the occurrence of hemiplegia on the side opposite to that which has been struck, the surgeon is warranted in making an aperture in the skull at the seat of injury, in order to remove the blood that has been poured out, and to arrest its further effusion. ^ But the instances in which this assemblage of symptoms could exist, with sufficient precision to justify an operation, are excessively rare. Out of some hundred cases of serious and fatal injury of the head that have been admitted into University College Hospital during the last fifteen years, in one case only, I believe, has it been found advisable to have recourse to trephining for the removal of extravasated blood. The case to which I refer was that of a man admitted comatose three days after an injury of the head occasioned by the fall from a cab. There were no serious symptoms for some hours after the acci- dent, but then stupor gradually came on, amounting at last to complete coma. On examination^ a bruise of the scalp was found on the left temple: through this I made an incision, and finding a starred fracture over the sinus of the middle meningeal artery, trephined the bone, when a large coagulum was found lying upon the dura mater, and on removing this fluid, arterial blood freely welled up. The coma was relieved by the operation, and the patient made a good recovery. The most serious objection to the application of the trephine in cases of extravasation does not, however, consist so much in determining the existence of effused blood within the cranium, or that the extravasation is of OPERATION OF TREPHINING. 295 the meningeal form, but rather in diagnosing that it is so seated between the dura mater and the skull as to admit of removal; not being effused at the base, or so widely coagulated over the surface of the brain as to be unable to escape through the aperture that may be made. The likelihood of the co-existence of fracture of the base of the skull and of laceration of the brain, giving rise to the cerebral form of extravasation, must also be taken into account. For these various reasons, surgeons now very properly content themselves, in the great majority of cases of extravasation, with the employment of antiphlogistic treat- ment, on the principles already stated. With this view, the head should be shaved, the ice-bladder applied, the patient bled, purged, and kept at perfect rest. If, however, the signs are urgent, and pretty clearly indicate the menin- geal form of extravasation, and more especially if there be hemiplegia on the side opposed to that on which the blow has been received, with an injury in the course of the middle meningeal artery, the trephine may be applied at the seat of injury and the blood removed. It must be borne in mind that, however clear the signs, the extravasation may not be met with where the surgeon expects to find it. Under these circumstances it is better not to prosecute the search by making fresh trephine apertures. In no case would a prudent sur- geon trephine over the course of the middle meningeal artery, in the absence of local symptoms, on the chance of finding the blood there, as has been recom- mended by some of the older surgeons. Operation of Trephining. — Before concluding the subject of injuries of the head, it is necessary to say a few words on the operation of trephining, which, though far less commonly employed in the present day than heretofore, is one of sufficient frequency in practice, as well as of great importance from the serious nature of the cases that usually require it. The trephine may be applied to the cranium for two purposes; either with the view of preventing inflammation and its consequences, or for the purpose of removing some cause of compression. The only case in which preventive tre- phining is practised by modern surgeons is that for the punctured or starred fracture of the skull, without stupor; in all other instances in which it is called for, the object of its application is the removal of a cause of compression or of irritation of the brain, such as a depressed portion of bone, foreign bodies either fixed in the skull, or lying close under it, and pus or blood extravasated within the cranium. The operation of trephining is by no means a favorable one in its results. Of 45 cases reported by Dr. Lenter, as occurring at the New York Hospital, in which, however, there is no distinction made between the application of the trephine proper and of various instruments, such as the elevator, Hey's saw, &c, belonging to a trephining case, only 11, or about one-fourth, recovered. Of 13 cases in which the trephine proper was used at University College Hospital, by Mr. Cooper, Mr. Liston, and myself, 4 patients recovered; 1 other died of injury of the spine unconnected with the operation, and the remaining 8 died of inflammation of the brain or its membranes. The Parisian surgeons have not been very successful. Nelaton says, that all the cases of injury of the head, in which the trephine has been used in the Parisian hospitals during the last fifteen years, and they are 16 in number, have terminated fatally. The trephine should have a well-tempered crown, serrated half-way up its exterior, the teeth should be short and broad, and not too fine; the centre pin must not project more than about the eighth of an inch, and care must be taken that the screw which fixes it is in good working order. The other instruments required are a Hey's saw, an elevator that will not readily snap, and a pair of strong dissecting forceps. The operation itself should be conducted in the following way: — The head having been shaved, and the portion of the skull to which the trephine is to be 296 INJURIES of the spine. applied having been freely exposed by means of a crucial or T-shaped incision, or by the enlargement of any wound that may exist, the trephine with the centre pin protruded and well screwed down, is to be firmly applied until its teeth touch the skull; it is then worked with rather a sharp, light, and quick movement, the pressure being exercised as the hand is carried from left to right. The centre pin must be withdrawn so soon as a good groove is formed by the crown, lest it perforate the skull first and injure the dura mater. In this way the outer table of the skull is quickly divided, and the diploe cut into; the detritus which now rises by the crown of the trephine is soft and bloody, instead of being dry, as it is whilst the outer table is being sawn. As the instrument approaches the dura mater, the sawing must be conducted more warily, and must every now and then be interrupted, in order that the surgeon may examine with the flat end of a probe, or with a quill, the depth that has been obtained, care being taken that this is uniform throughout the circle. The surgeon now makes each turn very lightly, and now and then tries with a slight to-and-fro movement whether the circle of bone is loose. So soon as it is, he withdraws it in the crown of the trephine, or raises it out by means of the elevator. In this operation the dura mater must not be wounded; if it be injured fatal con- sequences will probably ensue. The objects for which the trephining has been had recourse to must now be carried out, depressed bone elevated or removed, and pus or blood evacuated. The scalp should then be laid down again, a few sutures and a piece of water-dressing being applied. There are certain parts of the skull, over the venous sinuses, for instance, and near the base, to which no prudent surgeon would apply the instrument. So also, if it were ever thought necessary to trephine at the frontal sinuses, the outer table must first be removed with a large crown, and the inner table sawn out with a smaller one. After the operation careful attention must be paid to antiphlogistic measures of a preventive and curative kind, the great danger to be apprehended being inflammation of the brain and its membranes. In some cases also there is reason to believe that suppurative phlebitis of the sinuses and veins of the diploe have been the cause of death. CHAPTER XIX. INJURIES OF THE SPINE. Injuries of the spine, like those of the head, derive their importance from the degree to which the enclosed nervous centre is implicated. The spinal cord is subject to concussion, compression, and inflammation, as the result of external violence, and any of those conditions may occur without injury to the osseous and ligamentous structures investing it, although, in the majority of cases, they are directly occasioned by fracture or dislocation of the vertebras. It may also be partially or completely divided by cutting-instruments, gun-shot wounds, or a broken vertebra. Concussion of the spine varies greatly in severity. In many cases of falls from a height, and' of blows upon the back, the patient complains of great pain at some part of the spine, inability to stand, and a certain degree of weakness of the lower extremities. In these cases, rest for a few days in bed, and more especially the application of dry cupping, or the abstraction of a few ounces of blood from over the seat of injury, will speedily remove the symptoms. WOUNDS OF THE SPINAL OORD. 297 In other instances, however, the symptoms, slight at first, quickly become much increased in severity, or may, from the commencement, assume a serious character. In such cases, there is some pain at the seat of injury, below which there is more or less complete paralysis, sometimes consisting in mere debility or impaired mobility of the lower limbs, at others of loss of sensibility and motion. The sphincters are always affected, there being more or less incontinence of flatus and faeces, and some difficulty in emptying the bladder, amounting at last to complete retention of urine. These symptoms may, after continuing for some weeks or months, gradually lessen in intensity until mere debility is left, which, however, is apt to continue for a considerable time. In other cases again, they continue permanently, or terminate in speedy death. In the more chronic forms of the affection, traumatic myelitis, usually of a fatal character, is apt to come on. In these cases there is paralysis of the parts below the seat of injury, associated with pain and twitching of the muscles, the pain in the back being much increased on pressure. After death in cases of concussion of the spinal cord, every condition is found between slight ecchymosis, with some redness of the membranes, through all the gradations of softening up to complete disorganization of its structure. In many cases there is extravasation of blood into the substance of the cord itself. When this occurs the clot is most commonly found in the grey substance, or if not actually confined to this, at all events, towards the centre of the cord and oppo- site the seat of injury. Occasionally blood is effused largely into the spinal canal, compressing the cord, and thus occasioning gradually increasing para- plegia. Sir A. Cooper mentions a case in which this happened as the result of a strain, the patient dying at about the end of a twelvemonth. When myelitis has occurred, the membranes are found congested and sloughy, and the cord itself in every degree of red softening up to complete liquefaction. In the treatment of concussion of the spine it is necessary to keep the patient in the recumbent position until the lower limbs have regained their power. The most convenient attitude for this purpose is upon the prone couch, which will be described when we come to speak of diseases of the spine. The patient should be cupped over the seat of injury, have his water drawn off, his bowels opened by enemata, and his strength supported by a nourishing system of diet, which must be continued so long as the paralysis lasts. After a time, more especially if the bladder continues weak, blisters should be applied to the spine, and when merely a degree of debility is left in the lower limbs, the raw surface so produced may advantageously be sprinkled with strychnine properly diluted with starch. Wounds of the spinal cord may occur from stabs with pointed instruments, from gun-shot violence, or more frequently from the injury inflicted upon it by the pressure of fractured vertebrae. In the latter form of injury there is an associa- tion of wound and compression, giving rise essentially to the same symptoms as if the cord were divided. When the spinal cord is completely divided a certain set of symptoms occur that are common to all cases, at whatever part of the cord the injury has been inflicted, provided it be not so high up as to cause instant death. In the first place there is complete paralysis of sense and motion in all parts below the seat of injury, though the mental manifestations continue intact. The precise seat of injury may Often be diagnosed by the extent of the paralysis. Thus in injury of the lower part of the spine there may be paralysis of all those parts supplied by the nerves of the sacral plexus, whilst those from the lumbar are not affected, the sensibility being lost below the knees, whilst above it is perfect — thus leading to the inference that the injury has been inflicted above the ohe and below the other set of nerves. The temperature of the part becomes lowered; though in some cases when the paralysis is not quite complete, the reverse has been observed; and after a time, a visible diminution takes place in 298 INJURIES OF THE SPINE. its nutritive activity, the circulation becoming feeble, with a tendency to conges- tion at depending points. This lessening of nutritive vigor is not, however, con- fined to the paralyzed parts, but the whole of the system participates in it, the patient becoming speedily anemic and cachectic. The skin assumes a dirty cadaverous hue.^nd the cuticle usually exfoliates in branny flakes. These general symptoms of paralysis as the result of injury present important modifications according to the point at which the cord is divided. When the injury has been inflicted in the lumbar or lower part of the dorsal region, there will be found to be complete paralysis of all the parts supplied by the nerves given off from the sacral or lumbar plexuses, or both; hence there will be paralysis of the lower extremities, of the-genital organs, and of the trunk as high as the seat of injury. There is always in these cases relaxation of the sphincter ani, and hence incontinence of flatus, and, to a great extent, of faeces. There is at first retention of urine in consequence of the paralyzed state of the bladder, the body of which is unable to expel its contents; after a time, how- ever, the urine dribbles away as fast as it is poured into the over-distended organ, the neck of which has lost its contractile sphincter-like action. After the first few days the urine will be observed to be ammoniacal in odor, and alka- line in reaction. This is probably owing to changes that it undergoes after it has passed into the bladder, the mucous membrane of which becomes chroni- cally inflamed, secreting a viscid alkaline muco-pus, which mixes with the urine. In the early stages of the accident the penis will usually be observed to be in a state of semi-erection. Patients who have met with injuries of this portion of the spinal cord may live for many months and even for a year or two, but even- tually die, usually with sloughing of the nates, or from the supervention of some intercurrent visceral inflammation of a low type. When the cord is divided in the upper dorsal region, about the level of the third dorsal vertebra, we have not only the train of symptoms that has just been mentioned as characteristic of this injury lower down, but another set of symptoms is superadded to them, owing to the respiration being interfered with in consequence of the paralysis of the greater portion of the expiratory muscles. The intercostals, and those constituting the abdominal wall, no longer acting, an imperfect expiration is solely effected by the elasticity of the walls of the chest, and those expiratory movements, such as sneezing and coughing, which are of a muscular character, cannot be accomplished. In these cases it will be noticed, that during inspiration, which is effected almost exclusively by the diaphragm, the ribs are depressed instead of being expanded and raised, and the abdominal wall, which is soft and flaccid, is protruded far beyond its normal limits. In consequence of the impediment to' respiration the blood is not properly arterialized, and a slow process of asphyxia goes on, usually running into congestive pneumonia, and terminating fatally in about a fortnight or three weeks. When the injury is situated in the lower cervical vertebrae, not only do all the preceding symptoms occur, but there will be paralysis of the upper extremi- ties as well, and the inspiration being entirely diaphragmatic, the circulation speedily becomes affected, the countenance assuming a suffused and purplish look. If the cord have been divided immediately above the brachial plexus, the whole of the upper extremities will be completely paralyzed; but if the injury be opposite the sixth cervical vertebra, it may happen that the upper extremities are only partially paralyzed. This happened in two cases of fracture of the spine in this region that have lately been under my care at the hospital. In both these instances the paralysis existed on the ulnar but not on the radial side of the arms, owing to the external cutaneous and radial nerves arising higher from the plexus than the ulnar, and thus just escaping injury. It is remarkable that in both these cases there was acute cutaneous sensibility in the arms along the whole line of junction between the paralyzed and the sound FRACTURES OF THE SPINE. 299 parts. In. cases of injury of the cord in this situation death usually occurs by asphyxia in the course of a week. When the division of the spinal cord takes place above the origin of the phrenic nerve, opposite to or above the third cervical vertebra, instantaneous death results from the paralysis of the diaphragm, as well as of the rest of the respiratory muscles, inducing sudden asphyxia. It occasionally happens in partial division of the cord, as in some cases of compression resulting from fracture, that the symptoms are not so clearly marked as in the instances that have just been recorded. Thus, for instance, the para- lysis may not extend to all the parts below the seat of injury; it may be attended by severe pain in some of the semi-paralyzed parts; or, motion may be affected in one limb, and sensibility in another. These deviations from what is usual may generally be explained by some peculiarity in the seat of the injury to the cord, or by the extent of its division. Fractures of the spine commonly result either from direct blows upon the back, or else by falls upon the head, in such a way that the body is violently bent forwards. The signs of this injury, though by no means unequivocal in many cases, are yet sufficiently obvious in the majority of instances to admit of an easy diagnosis. They are of two kinds; those presented by the injury of the bone. and those dependent on injury by compression or laceration, or both, of the spinal cord. The local signs are usually pain at the seat of injury, greatly increased on pressure or on moving the part, inequality of the line of the spinous processes, with depression of the upper portion of the spine, and corresponding prominence of the lower. There is an inability to support the body in the erect position, and to move the spine in any way; hence, when the upper portion of the column is injured, the patient holds his head in a stiff and constrained attitude, fearing to turn it to either side. The more general symptoms of fracture of the spine are dependent upon the injury that the cord has received. If the fracture have not implicated the spinal canal, as when only the tip of a spinous process has been broken off, or if it be unattended by displacement, although it may traverse the body and arches, no symptoms depending upon injury of the cord need exist, and indeed occasionally are absent. But in these cases even there is usually some degree of paralysis, owing perhaps to the concussion to which the cord has been sub- jected at the moment of injury; and occasionally a sudden movement by the patient will bring on displacement, by which the cord is compressed and all the parts below the injured spot paralyzed. A woman was admitted into University College Hospital with an injury of the neck, the nature of which could not be accurately ascertained. She was in no way paralyzed, but kept her head in a fixed position. A few days after admission, whilst making a movement in bed, by which she turned her head, she fell back dead. On examination it was found that the spinous process of the fifth cervical vertebra had been broken off short, and was impacted in such a way between the arches of this and the fourth as to compress the cord. This impaction and consequent compression probably occurred at the time of the incautious movement, thus producing immediate death. When there is only partial displacement of the fracture there may be but incomplete, paralysis of the parts below the injury; of one arm, one leg, &c. In these cases there is usually great pain experienced at the seat of fracture, and extending from it along the line of junction between the paralyzed and sound parts round the body or along a limb. This symptom, which is of great importance as exactly defining the seat of injury, is owing, as I found in a case of fracture of the sixth cervical vertebra under my care, to the fractured bone compressing and irritating the nerve that issues from the vertebral notch opposite the seat of injury. 300 INJURIES OF THE SPINE. In the majority of cases of fracture of the spine there is, however, such dis- placement of the bone as to compress the whole thickness of cord, and thus to occasion complete paralysis. In these cases the symptoms are such as have been detailed when speaking of injuries of the spinal cord on the compression, laceration, or divisions of which they are dependent. Fractures of the spine are inevitably fatal, death ensuing in the two different ways, and at the different periods that have already been mentioned. The treatment of these injuries is sufficiently simple. No attempt at reduc- tion can of course be made. All our efforts must be directed to the prolonga- tion of life. With this view, if the fracture be in such a situation, at any point below the upper dorsal vertebra, for instance, as will hold out a prospect of the life being prolonged for a few weeks or months, means must be taken to prevent the occurrence of sloughing of the nates, an accident that is of common, and usually of fatal termination in these cases. 'The patient should therefore be laid at once on a water-bed, cushion, or mattress; he must be kept scrupulously clean, and his urine should be drawn off twice in the day at regular hours. If, as usually happens after a time, the bowels become confined, relief must be afforded by castor oil, or turpentine enemata. A nourishing diet must be administered, and perfect rest in one position enjoined. In this way life may be maintained for a considerable length of time; and it is probable that ossific union of the fracture may sometimes take place, though the patient may not recover from the paralysis, and will die eventually from disease of the cord. In cases of fracture of the spine with depression of the arches, it has been proposed to trephine the injured bone and elevate the fragment that has been driven in upon the cord. This operation, though performed by Cline, Cooper, and Bell, is, I believe, now generally abandoned by the best surgeons in this country, owing to its invariable, and, indeed, intrinsically fatal character. Dislocations of the spine. — On looking at the arrangement of the articular surfaces of the vertebrae, the very limited motion of which they are susceptible, and the way in which they are closely knit together by strong ligaments and short and powerful muscles, it is obvious that dislocations of these bones must be excessively rare. So seldom indeed do they occur that their existence has been denied by many surgeons. But yet there are a sufficient number of instances on record to prove incontestably that these accidents may happen. Those cases that have been met with have usually been associated with partial fracture, but this complication is not necessary. In all, the displacement was incomplete, and indeed a complete dislocation cannot occur. The dislocation of the atlas from the occipital bone has only been described in two instances; —by Lassus and by Paletta. In the case by Lassus, death ensued in six hours, and the right vertebral artery was found to be ruptured. In the other case, the patient is said to have lived for five days, but the report is so_ incomplete that little value can be attached to it. Dislocations of the axis from the atlas are of more frequent occurrence. They may happen with or without fracture of the odontoid process. In either case the axis is carried backwards, and the spinal cord thus compressed. This accident is said to have taken place by persons in play lifting a child off the ground by its head; the combination of rotation and traction in this movement being especially dangerous, and liable to occasion the accident. For the same reasons it has been met with in persons executed by hanging. Death would probably be instantaneous under these circumstances. It has, however, been stated that in dislocations of this kind, life has been saved by the surgeon placing his knees against the patient's shoulders, and drawing or twisting the head into position. This, however, I cannot believe possible, if the displace- ment have been complete, as death must be instantaneous; the cases of supposed dislocation and reduction having probably been instances of concussion of the cord with sprain of the neck. INJURIES OF THE FACE. 301 Dislocation of any one of the five lower cervical vertebrae may occur. These injuries are usually associated with fracture, but sometimes, though rarely, they happen without this complication. In these dislocations, as in those that have already been described, the displaced bone carries with it the whole of that por- tion of the vertebral column which is above it, no single bone being dislocated both from those above and those below it. These accidents most commonly happen by forcible flexion of the neck for- wards, though traction and rotation conjoined have occasioned them. In a case of luxation of the sixth from the seventh cervical vertebra, recorded by J. Roux, the accident happened by a sailor plunging into the sea for the purpose of bathing, coming head foremost against a sail which had been spread out to prevent the attack of sharks; he died on the fourth day. In a patient of mine who fell out of the window in such a way that the head was doubled forwards upon the chest, and who was brought to the hospital with supposed fracture of the spine, we found after death, which occurred on the fifth day, that the seventh cervical vertebra had been dislocated forwards from the first dorsal, there being a wide gap posteriorly between the lamina of these bones, with horizontal split- ting of the intervertebral substance, detaching with it an extremely thin and small layer of bone from the body of the seventh. There was no fracture about the articular processes, which were completely separated from one another. The symptoms of this accident are necessarily excessively obscure, being very liable to be confounded with those of fracture. Reduction has been effected in a sufficient number of cases of this kind to justify the proceeding being adopted when the danger is imminent. Dislocation of the transverse processes of the cervical vertebrae occasionally occurs. In these cases the patient, after a sudden movement, or a fall on the head, feels much pain and stiffness in the neck, the head being fixed immovably, and turned to the opposite side to that on which the displacement has occurred. In these cases I have known reduction effected by the surgeon placing his knees against the patient's shoulders, drawing on the head, and then turning it into position, the return being effected with a distinct snap. INJURIES OF THE FACE. Cuts about the cheeks and forehead are of common occurrence. These injuries present nothing peculiar, except that the structures of the face partake of the same tendency to ready repair, as well as to the supervention of erysipeloid in- flammation, that characterize the scalp when injured. In the treatment of these wounds it is of much consequence to leave as little scarring as possible. Hence the edges, after being well cleaned, should be brought neatly into apposition by fine hare-lip pins and the twisted suture, or by a few points of interrupted suture; more particularly if they are in a transverse direction, and implicate the lips or nose. When in the neighborhood of the eyelids, especial care must be taken to prevent any loss of substance, lest the contraction of the cicatrix produce eversion of the lid. In those cases in which a portion of the nose or lip has been lost, much may be done to repair the deformity by properly-con- ducted plastic operations, as will be described when we come to treat of diseases of these structures. The bleeding, which is often rather free in wounds of the face, in consequence of some arterial branch having been divided, may often be arrested by passing the hare-lip pin under the vessel, and applying the twisted suture above it, so that it may be compressed. If the lip is cut from within, by being struck against the teeth, the coronary artery may be divided, the patient swallowing the blood that flows into the mouth. Some years ago, a man , was brought to the hospital, drunk, and much bruised about the face. Shortly after his admission he vomited up a large quantity of blood, which was at first supposed to proceed from some internal injury, but on examining his mouth, it 302 INJURIES OF THE NOSE AND EARS. was found that the blood came from the coronary artery of the lip, which was divided, together with the mucous membrane. It occasionally happens as the result of wounds or abscesses of the cheek that the parotid duct is cut across, in consequence of which the wound does not close, a trickling of saliva taking place upon the outside of the cheek, so as to establish a salivary fistula, a source of much disfigurement and inconvenience to the patient; the surface surrounding it being puckered in a somewhat exco- riated, and the fistula opening by a granulating aperture. If this condition is recent, a cure may sometimes be accomplished, by paring the edges of the external wound, bringing them into close apposition, and apply- ing pressure upon the part. If it be of old standing, the probability is that the aperture into the mouth is closed, and that something more will be required than bringing the lips of the wound together. To get it to close, we may adopt the plan recommended by Desault, of passing a small seton from the mouth into the fistula, so as to make an artificial opening into the mouth, and then, when the course of the saliva has thus been established, closing the external wound. In order to make the internal artificial opening permanently fistulous, some sur- geons have advantageously employed a red-hot wire. Besides the fistula of the Stenonian duct, other fistulous apertures may take place in the cheek, as the result of injury or disease, allowing the escape of a small quantity of saliva. These openings are always difficult to heal: the edges becoming callous, and not readily taking on reparative action. Closure may be effected in some cases by cauterization with the nitrate of silver, or with a red- hot wire, due attention being paid to the general health. In other cases, again, the electric cautery, as employed by my colleague, Mr. Marshall, may prove successful. If, however, the opening be free, with much indurated structure about it, the surgeon may find it necessary to excise a portion of the edges before bringing them together. Feneign bodies in the nostrils, such as pebbles, beads, dried peas, &c, are occasionally met with in children, having been stuffed up in play, and becoming so firmly fixed as to require extraction by the surgeon. For this purpose a pair of urethral or polypus forceps will usually be found convenient. In some cases, however, a bent probe or an ear-scoop will remove the impacted body most easily. The Ears are not unfrequently wounded in injuries of the head and scalp; a portion of the external ear being sometimes torn down and hanging over the side of the face. In these cases, as in scalp injuries, the part should never be removed, but, however lacerated and contused, should be cleaned and replaced by means of a few points of suture and strips of plaster. When the cartilaginous por- tion of the ear is divided, nice management is usually required in effecting perfect union. Foreign bodies are often pushed into the ears of children in play with one another. When pointed or angular, such as pieces of stick, they may readily be extracted with forceps; but when round and small, such as pebbles or beads, they are not so easily removed. Here the use of this instrument is of little service, the bent ear-scoop •may occasionally be got round the body and thus remove it. In some cases I have found an instrument, as here represented, fig. 131, and made by Coxeter on the model of Civale's urethral scoop, useful in getting a foreign body out of the ear. It can be introduced straight and then passed beyond it, when, by the action of a screw in ^ the handle, the scoop is curved forwards, and so enables extraction to be readily effected. In other cases it is best got out by forcibly syringing the ear with tepid water, injected by means of a large brass syringe in a full stream, the pinna being drawn up so as to straighten the external Fig. 131. INJURIES OF THE EYES. 303 meatus. In this way the bead or pebble is soon washed out by the reflux of the water striking against the tympanum. Should these means not suffice it is better to leave matters alone, and to allow the foreign body to become loosened, than to poke instruments into the ear with the view of forcibly extracting it. These attempts are ill-advised, and I have known death follow prolonged and unsuccessful efforts at the extraction of a pebble from the ear. Injuries of the orbit if deep are always serious, on account of the prox- imity of the brain; thus it may happen that a pointed body, such as a pieceof stick or a knife thrust into the orbit, perforates its superior wall, thus producing a fatal wound of the brain. Occasionally inflammation is set up in the loose cellulo-adipose tissue contained in this cavity, giving rise to abscess, which may point in either eyelid; or, to inflammation extending itself to the encephalon. In other cases wounds of the orbit may be followed by loss of vision, without the eyeball being touched, either in consequence of injury of the optic nerve, or perhaps from the division of some of the other nerves of the orbit producing sympathetic amaurosis, as occasionally happens even from ordinary wounds of the face, implicating some of the terminal branches of the fifth pair. Injuries of the eye-ball are so commonly followed by impairment or total loss of vision as to constitute a most important series of accidents; the delicacy of the structure of this organ being such, that slight wound of its more trans- parent parts, or displacement of the lens, is often followed by complete opacity and loss of sight. Injuries of this organ may be divided into contusions and wounds. A contusion of the eyeball, without rupture or apparent injury of any of its structures, may give rise to such concussion of the retina as to be followed by temporary or permanent amaurosis. More frequently contusions of the eye are accompanied by extravasation of blood under the conjunctiva, and much ecchy- mosis of the eyelids. A " black-eye " is best treated by the continuous applica- tion of a weak arnica and spirit lotion. Contusion of the eye with rupture of some of the structures of the ball is a most serious accident. The cornea may be ruptured, the humors lost, and vision permanently destroyed. Most frequently the rupture is internal, the outer tunics escaping all injury. In this case we may have an extravasation of blood into the eye, completely filling the anterior chamber, hiding and compli- cating deeper mischief within the ball. This condition, termed hamophthalmia, is frequently associated with separation of the ciliary margin of the iris. In other cases again, there may be displacement of the crystalline lens, which may be driven into the vitreous humor, be engaged in the pupillary aperture, or fall forwards into the anterior chamber. As a consequence of such injuries the eye usually becomes inflamed with intense frontal and circum-orbital pain : disorga- nization of the ball, and ultimately loss of vision ensuing. The treatment of these injuries must always be of an active antiphlogistic character. Blood should be freely taken from the arm by venesection, and from the temple by cupping, the iris being dilated by the application to the eye of a solution of the sulphate of atropine, of the strength of two grains to the ounce of distilled water; the patient must be kept in a darkened room, on a strictly antiphlogistic regimen, and should be put under the influence of calomel and opium, as speedily as possible. In this way, the inflammation will be sub- dued, the effused blood absorbed, and perhaps vision restored. In some cases, however, opaque masses and bands of lymph will be deposited in the anterior chamber and the pupillary aperture, preventing more or less completely the entry of light. If the lens be displaced into the posterior chamber it must be left there; if in the anterior it may be extracted through the cornea. Wounds of the eyeball may be divided into those that are merely superficial, and do not penetrate into its chambers; and those that perforate its coats. The non-penetrating wounds are usually inflicted by splinters of iron, or other 304 WOUNDS OF THE MOUTH AND TONGUE. metallic bodies, which become fixed in the cornea, or between one of the eyelids and the ball. Very painful and troublesome injuries are sometimes inflicted by scratches of the eyeball with the nails of children. In the treatment of these superficial injuries, the first point is necessarily to remove any foreign body that is lodged. If it be fixed on the cornea, as commonly happens, it may be picked off with the point of a lancet or cataract needle; if it is a splinter of iron that has been so lodged, it is well to bear in mind that a small brown stain will be left after the metallic spicula has been taken off; this, however, will disappear in the course of a few days. In order to remove foreign bodies lodged between the ball and the eyelids, these must be everted so that the angle between the palpebral and ocular conjunctiva may be properly examined. ^ For this purpose the lower eyelid need only be drawn down, whilst the patient is directed to look up ; but the eversion of the upper eyelid requires some skill. It is best effected by laying a probe horizontally across it, immediately above the tarsal cartilage; the surgeon then taking the eyelashes and ciliary margin lightly between his finger and thumb, draws down the eyelid at the same time that he everts it by pressing the probe firmly backwards and downwards against the eyeball; the patient should then look down in order that the whole of the upper part of the conjunctiva, where the foreign body will probably be found, may be carefully examined. Penetrating wounds of the eyeball present great variety; they are commonly inflicted by bits of stick, steel pens, children's toys, and not unfrequently during the shooting season by the explosion of faulty percussion caps, or the lodgment of a stray shot in the eye. In all cases these accidents are highly dangerous to vision, and when the foreign body lodges, it is usually permanently lost. The danger that ensues usually arises either from the eye being opened to such an extent that the humors escape, or else, that the iris becoming engaged in a wound in the cornea, a hernial prolapse of it occurs. The remoter conse- quences usually arise from inflammation taking place within the globe, so as to produce an opaque cicatrix of the cornea or of the capsule of the lens; or else there is danger that adhesions may form, stretching across between the iris and the lens, or between these parts and the posterior surface of the cornea; or that inflammation may take place in all the structure of the ball, giving rise to dis- organization of it. The treatment of these penetrating wounds is strictly antiphlogistic. Bleeding in the arm, cupping on the temples, low diet, a darkened room, and the admin- istration of calomel and opium, are the principal points to be attended to. If the iris have protruded through a wound in the cornea, it should be carefully pushed back, and a drop or two of the solution of atropine put upon the eye. If it cannot be returned, it may be removed with a pair of fine curved scissors, and at a later period any staphylomatous tumor that may form, should be touched repeatedly with a pointed piece of nitrate of silver. If there is a tendency to the formation of adhesions, or to the deposit of lymph within the pupil or the anterior chamber, our principal reliance should be upon small doses of calomel, in conjunction with opium. If the lens or its capsule have become opaque traumatic cataract thus forming, extraction may be required at a later period of the case. Wounds of the mouth are seldom met with, except as the result of gun- shot violence. In these cases the amount of injury done to the soft structures, however great, is usually only secondary to the mischief that results to the brain, spinal cord, jaws and skull, and must of course be treated on the ordinary principles of gun-shot and lacerated wounds. Wounds of the tongue usually occur from its tip or sides being caught between the teeth during an epileptic fit. They have been known to be inflicted purposely by insane patients, in attempts to excise this organ. Should the hemorrhage be free, the application of a ligature, or even of the actual cautery, may be needed to arrest it. These wounds generally assume a sloughy appear- INJURIES OF THE THROAT. 305 ance for a few days; then clean up, and granulate healthily. It is useless to bring the edges together by sutures, which readily cut out. If a large portion of the tip be nearly detached, it must, however, be supported in this way; but the threads should be thick, and passed deeply. The palate and the pharynx are sometimes lacerated by gun-shot injuries of the mouth; or the wound may result by something that the patient happened to have between his lips being driven forcibly backwards into his mouth. Thus, a tobacco-pipe may, by a blow on the face, be driven deeply into the substance of the tongue, or perhaps into the pharynx, wounding and lodging behind the arches of the palate, breaking off short; the fragment that is left in giving rise to abscess, to ulceration of the vessels, and perhaps fatal secondary hemorrhage. In a case that was under my care a short time back, the soft palate was nearly completely detached from the palatal bones by a deep transverse wound, caused by the end of a spoon being forcibly driven into the mouth. INJURIES OF THE THROAT. The cartilages of the larynx may be displaced, dislocated as it were by violent blows; or they may be fractured, though but very rarely, the rupture in some cases taking place transversely, in others longitudinally. Digital examination of the part would at once detect the nature of the injury. In all these injuries there is danger of asphyxia, which indeed may be induced by simple concus- sion of the larynx. Should these symptoms be very urgent, tracheotomy might be required. If not, attention to position and support of the head will suffice. Wounds of the throat are of great frequency and importance, implicating as they do some of the most important organs in the body. They may be divided into three categories : — 1st. Those that do not extend into the air or food passages. 2nd. Those that implicate the air-passages, with or without injury of the oesophagus. 3rd. Those that are accompanied by injury of the spinal cord. All these injuries are most commonly suicidal, and may be inflicted with every variety of cutting instrument. Hence, though incised, they are often jagged, and partake somewhat of the character of lacerated wounds, with great gaping of the edges. In wounds of the first category there is very commonly free and even fatal hemorrhage, and this sometimes though none of the larger arterial or venous trunks are divided; the blood flowing abundantly from the venous plexuses and from the thyroid body. If the larger arteries are touched, as the carotid and its primary branches, the hemorrhage may be so abundant as" to give rise to almost instantaneous death. Another source of danger in these cases proceeds from the admission of air into the veins of the so-called "dangerous region" of the neck. For this a free wound" is by no means necessary, as is instanced by a remarkable case that occurred a few years ago near London, in which the intro- duction of a seton into the fore part of the neck was followed by death, from this cause. The large nerves, such as the vagus and phrenic, cannot, in a suicidal wound, be divided without injury to the neighboring vessels. The division, however, of the respiratory nerves on one side only, or even of one of them, would in all probability be fatal in man, by interfering with the proper performance of the respiratory act. In a case with which I am acquainted, in which the phrenic nerve was divided during the operation of placing a ligature on the subclavian artery, death resulted in a few days from inflammatory congestion of the lungs. In the treatment of wounds of the neck of this category, the principal points to be attended to are, in the first place, the arrest of hemorrhage by the ligature of all bleeding vessels, whether arterial or venous; and, secondly, bringing together 20 306 INJURIES OF THE THROAT. the lips of the wound. If the cut be longitudinal, this may be done by strips of plaster. If transverse, by a few points of suture and by position, the head being fixed, with the chin almost touching the sternum, and retained in this posture by tapes passing from the nightcap to a piece of bandage fixed round the chest. I have had under my care one case, in which, owing to the projection and mobility of the larynx, the wound did not unite, a large and deep gap being left, which required a series of plastic operations in order to effect its closure. The air-passages are commonly wounded in suicidal attempts. They maybe known to be opened by the air being heard and seen to bubble in and out of the wound during respiration. These wounds vary much in extent, from a small puncture with the point of a penknife to a cut extending completely across the throat, and even notching the vertebrae. They are frequently complicated with injuries of the larger vessels and nerves, and sometimes with wound of the oeso- phagus. Most commonly the cut is made high up in the neck, for the suicide thinking that it is the opening into the air-passages that destroys life, draws the razor across that part of the throat where these are most prominent and easily reached; and thus, by not wounding the larger vessels, which are saved by the projection of the larynx, frequently fails in accomplishing his object. There are four situations in which these wounds occur: 1st. Above the hyoid bone; the cut extending into the mouth and wounding the root of the tongue. When the wound is in this situation it is usually attended with a good deal of hemorrhage; and there is much trouble in feeding the patient, as the power of swallowing is completely lost. 2d. The wound may be inflicted in the thyro-hyoid space, laying the pharynx open, but being altogether above the larynx. This is the most common situa- tion for suicidal attempts. In many cases the incision is carried so low as to shave off or partly to detach the epiglottis and the folds of mucous membrane around it. In other cases again, the edges of the glottis or the arytenoid car- tilages are injured, the cut extending back to the bodies of the vertebrae. In these cases also, there is great difficulty in swallowing, and great risk of the sudden supervention of oedema glottidis, and consequent suffocation. 3d. When the larynx is wounded the incision is usually transverse; but I have seen a longitudinal cut made through the larynx, so as to split the thyroid and cricoid cartilages perpendicularly. In these cases of wounded larynx there is much danger of the blood from the superficial parts trickling into the air-pas- sages and asphyxiating the patient, and of inflammation of the bronchi and lungs supervening at a later period. 4th. Wounds of the trachea are not so common as those of the larynx, from which they differ but little in the attendant dangers. The oesophagus is seldom wounded, as it can only be reached through the trachea by a deep cut, which will probably implicate the large vessels on one side or the other. The spinal cord can only be injured by gun-shot wounds of the neck, which are necessarily fatal. There are various sources of danger in wounds of the neck implicating the air-passages. The hemorrhage, whether it proceed from any of the larger trunks, or consist of general oozing from a vascular surface, may either prove directly fatal by the loss of blood, or indirectly so in consequence of the blood trickling into the air tube, and by accumulating in its smaller divisions pro- ducing suffocation. Another source of danger in some of these cases arises from the supervention of asphyxia, either in the way that has already been men- tioned, or, in those cases in which the wound has been inflicted above the larynx, from the occurrence of oedema of the glottis. This condition may likewise occur in those cases in which the external opening is very small, and occasionally happens suddenly when the wound has nearly closed. Another source of danger is the loss of the natural sensibility of the glottis, in consequence of which it no longer contracts on the application of a stimulus. Hence food taken in by the mouth may pass into the larynx and make its WOUNDS OF THE THROAT. 307 appearance in the external wound, even though neither the pharynx nor the oesophagus have been wounded. This I have observed in many cases of cut- throat ; hence the presence of food in the wound cannot in all cases be con- sidered an evidence of injury to the food-passages. This occurrence is always a bad sign, and is never met with in the earlier periods of the injury; never, indeed, until a semi-asphyxial condition has come on, by which the nervous sen- sibilities are blunted, or until inflammation has been set up about the rima glot- tidis, giving rise to so much swelling as to interfere with the natural actions, and to deaden the perception of the part to the contact of a foreign body. In these cases also it will be found that the sensibility of the air-passages generally is much lowered, so that mucus accumulates in the bronchi often to a dangerous extent, the patient not feeling the necessity for expectoration, and often, indeed, having much difficulty in emptying his chest. The occurrence of bronchitis and pneumonia, either from the inflammation extending downwards from the wound, or in consequence of the cold air enter- ing the lungs directly; without being warmed by passing through the nasal cavi- ties, is perhaps the most serious complication that can happen in these injuries, and constitutes a frequent source of death in those patients who survive the immediate effects of the wound. The depressed mental condition of the patient also is usually unfavorable to recovery in all those instances in which the wound is suicidal, disposing him to the occurrence of low forms of inflammatory mischief. Treatment.—We have already considered the management of these wounds of the throat that do not interest the mucous canals in this region. When these are opened the same general principles are required as in the former case. Hemorrhage must be arrested by the ligature of all the bleeding vessels, whether arteries or veins, so that no oozing or trickling into the wound may take place. In some cases the hemorrhage consists principally of general venous oozing which cannot be stopped by ligature, the patient drawing a large quantity of blood into the air-passages through the wound in them. Under these circum- stances, I have found it useful to introduce a large silver tube into the aperture in the windpipe, and to plug the wound around it. So soon as the bleeding has fairly ceased, the plugs and the tube must be removed. The edges must next be brought together by a few stitches introduced at the sides, and by attention to position, the head being fixed by tapes as already described in the former section. I think with Liston that in these cases the wound should never be closely sewed up, or stitches introduced into the centre of the cut. If the edges of the integument be closely drawn together, coagula may accumulate behind them, in the deeper parts of the wound, so as to occasion a risk of suffocation, and as this must eventually close by granulation, no mate- rial advantage can possibly be gained by this practice. There is an exception, however, to this rule of not using stitches in the cen- tral part of the wound in cut-throats; viz., in those cases in which the trachea has been completely cut across. Here a stitch or two on either side of the tube is necessary, in order to prevent the wide separation of the two portions that would otherwise take place, owing to the great mobility of the larynx and upper end of the windpipe. In order to lessen the liability to inflammation of the lungs, the patient should be put into a room, the temperature of which is raised to about 80° Fah., with a piece of lightly folded muslin acting as a respirator laid over the wound. So soon as the cut surfaces begin to granulate, water-dressing may be applied, and the edge of the wound brought into apposition by strips of plaster, and a compress if necessary. During the treatment the principal danger pro- ceeds from inflammatory affections of the chest; these must accordingly be counteracted by the temperature in which the patient is placed, and by as active 308 INJURIES OF THE THROAT. antiphlogistic remedies as his condition will admit of. It must, however, be remembered that the mental depression and the bodily exhaustion from loss of blood, that are commonly met with in these cases, do not allow a very active course of treatment to be pursued. The administration of food in these cases is always a matter requiring much attention. As a general rule, the patient should be kept on a nourishing diet, with a moderate allowance of stimulants. If, as not uncommonly happens, the food passages are opened, in consequence of the wound extending into the mouth, the pharynx, or the oesophagus, it is of course impossible for the patient to swallow, and the administration of nourishment becomes a source of consider- able difficulty. This is best accomplished by means of an elastic gum catheter passed through the mouth into the gullet or stomach. This is easier than passing the instrument through the nose, and much better than introducing it through the wound. In this way a pint or more of the strongest beef tea, ox-tail soup, or Liebig's " Liquor Carnis," which I have used on one or two occasions with advantage, mixed with two or three eggs,..and having an ounce or two of brandy added to it, should be injected regularly night and morning, until the patient is able to swallow. In those cases in which the wound is above the larynx, there is occasional danger of the supervention of oedema of the glottis; should this occur, tracheotomy may become necessary in order to prolong the patient's life. As after-consequences of wounds of the throat, we occasionally find stricture of the trachea or aerial fistula occurring. If the cordas vocales happen to have been injured, loss of voice may result. Aerial fistula may sometimes form, owing to skin being adherent to the edges of the wound or air tube, and chiefly occurs when the cut is in the thyro-hyoid space; adhesion taking place between the integuments, which are doubled in as is seen in the os hyoides above, and the surface of the thyroid cartilage below. When this takes place, there is a tendency to the fistula continuing patent. Under these circumstances I have found the following operation successful in closing it: The edges of the fistulous opening being freely pared, and the knife passed under them for some distance, so as to detach them from subjacent parts, a vertical incision is made through the lower lip of opening — so as to split it downwards. Two points of suture are then inserted into each side of the hori- zontal incisions, bringing their edges in contact, but the vertical cut is left free for discharges and saliva to drain through. Unless this outlet be afforded, these fluids will burst through the sutures and cause them to cut out. ASPHYXIA. The surgical treatment of asphyxia includes the management of those cases in which respiration has been suspended by drowning, suffejcation, hanging, or the inhalation of irrespirable gases. The general subject of suspended anima- tion from these various causes cannot be discussed here, but we must briefly consider some points of practical importance in its treatment. In cases of drowning, life is often recoverable, although the sufferer has been immersed in the water for a considerable time, for it must be borne in mind that though immersed, he may very probably not have been submersed. The period after which life ceases to be recoverable in cases of submersion, cannot be very accurately estimated. The officers of the Humane Society, who have great experience in these matters, state that most generally cases are not recoverable that have been more than four or five minutes under water. In these cases, however, although submersion may not continue for a longer period than this, the process of asphyxia does; this condition not ceasing on the with- drawal of the body from the water, but continuing until the blood in the ASPHYXIA. — DROWNING. 309 pulmonary vessels is aerated, either by the spontaneous or artificial inflation of the lungs. As several minutes are most commonly consumed in withdrawing the body from the water and conveying it to land, during which time no means can be taken to introduce air into the lungs, we must regard the asphyxia as continuing during the whole of this period; occupying, indeed, the time that intervenes between the last inspiration before complete submersion to the first inspiration, whether artificial or spontaneous, after the removal of the body from the water. The latest time at which life can be recalled, during this period, is the measure of the duration of life in asphyxia. If, however, during this period, the action of the heart should cease entirely, I agree with Sir B. Brodie, that the circulation can never be restored. But although we may put out of consideration those marvellous cases of restoration of life that are recorded by the older writers, and which are evidently unworthy of belief, are we to reject as exaggerated and apochryphal cases such as that by Mr. Smethurst, in which recovery took place after ten minutes' submersion; that by Dr. Douglas of Havre, in which the patient was not only submersed, but had actu- ally sunk into, and was fixed in the mud at the bottom for from twelve to fourteen minutes; or that by Mr. Weeks, in which the submersion, on the testimony of the most credible witnesses, exceeded half an hour ? I think that it would be unphilosophical in the extreme to deny the facts clearly stated by these gentlemen. The more so that in these, as in many other instances of apparent death from drowning, life appears to be prolonged by the patient falling into a state of syncope at the moment of immersion. We should there- fore employ means of resuscitation, even though the body has been under water a considerable time. The means recommended by the Humane Society for the recovery of persons from drowning, and employed at their Institution in Hyde Park, appear to be well adapted for the treatment of the less severe forms of asphyxia, or rather for cases of syncope from fright and immersions in cold water. They consist, after the nose and mouth have been cleared of any mucosities, in the application of heat by means of a bath at about the temperature of 100° Fahr. until the natural warmth is restored; in the employment of brisk friction, and in passing ammonia to and fro under the nostrils. It is evident that these measures can have no direct influence upon the heart and lungs, but can only act as general stimuli to the system, equalizing the circulation if it be still going on; and, by determining to the surface, tending to remove those congestions that are not so much the consequences of the asphyxia, as of the sojourn of the body for several minutes in cold water; they would, therefore, be of especial service during the colder seasons of the year. A hot bath may also, by the shock it gives, excite the reflex respiratory movements. With the view of doing this with a greater degree of certainty, cold water should be sprinkled or dashed upon the face at the time that the body is immersed in the hot bath, as in this way a most powerful exciting influence can be communicated to the respiratory muscles; and the first object of treatment in all cases of asphyxia — the re- establishment of respiration — would more rapidly and effectually be accom- plished ; deep gaspings ensuing, by which the air would be sucked into the remotest ramifications of the air-cells, arterializing the blood that had accumu lated in the pulmonary vessels, enabling it to find its way to the left cavities of the heart, and thus to excite that organ to increased activity. These means, then, are useful in those cases of asphyxia in which the sufferer has been but a short time submersed, and in which the heart is still acting, and the respira- tory movements have either begun of their own accord on the patient being removed from the water, or in which they are capable of being excited by the shock of a hot bath, aided by the dashing of cold water in the face. At the same time, the lungs may be filled with pure air, by compressing the chest and abdomen, so as to expel the vitiated air, and then allowing them to 310 ASPHYXIA. recover their usual dimensions by the natural resiliency of their parietes. A small quantity of air will, in this way, be sucked in each time the chest is allowed to expand, and thus the re-establishment of the natural process of respiration may be much hastened. This simple mode of restoring the vital actions should never be omitted, as it is not attended with the least danger, and does not in any way interfere with the other measures employed. Dr. M. Hall has recommended that the patient be turned prone, so that the tongue may hang forwards, the larynx thus be opened, and that respiration be then set up by gentle pressure along the back, and by turning the patient on his side at regular intervals. If, by these means, we succeed in restoring the proper action of the respiratory movements, it will merely be necessary to pay attention to some points of the after-treatment that will presently be adverted to. Should we, however, fail in restoring respiration, we should have recourse to other and more active measures. In the more severe cases of asphyxia, warmth should be applied by means of a hot-air bath, by which not only the natural temperature of the body may be re-established, but the blood in the capillaries of the surface be decarbonized. The most direct and efficient means, however, that we possess for the re-esta- blishment of the circulation of these cases, is certainly artificial respiration. In this way the pulmonary artery and the capillaries of the lungs can alone be unloaded of the blood that has stagnated in them, and the left side and sub- stance of the heart will be directly and rapidly supplied by red blood. The whole value of artificial respiration depends, however, upon the way in which it is employed. Inflation from the mouth of an assistant into the nostrils or mouth of the sufferer, though objectionable, as air once respired is not well fitted for the resuscitation of the few sparks of life that may be left in the cases in which it is desirable to employ this means, yet in many instances is the readiest and indeed the only mode by which respiration can be set up; and should therefore always be had recourse to in the first instance, or until other and more efficient means can be got ready. Fig. 132. The bellows, if properly constructed for artificial inflation, so that the quantity of air injected may be measured, are no doubt very useful; and if furnished with Leroy's trachea-pipes, or, what is better, with nostril-tubes, may be safely employed. About 15 cubic inches of air may be introduced at each ASPHYXIA. — OVERLAYING. 311 stroke of the bellows, and these should be worked ten or a dozen times in the minute. The lungs should be emptied by compression of the chest before beginning to inflate, and after each inflation by compressing the chest and abdomen; but care must also be taken not to employ much force, lest the air-cells be ruptured. But the safest, and at the same time the most efficient, mode of introducing pure air into the lungs, is either by means of the split sheet, as recommended by Leroy and Dalrymple (fig. 132), or else by alternately com- pressing the chest and abdomen with the hand, and then removing the pressure so as to allow the thorax to expand by the natural resiliency of its parietes, and thus, each time it expands, to allow a certain quantity of air to be sucked into the bronchi. The quantity, introduced need not be large, for by the laws of the diffusion of gases, if fresh air be only introduced into the larger divisions of the bronchi, it will rapidly and with certainty find its way into the ultimate ramifications of these tubes. This last means of inflation has the additional advantage of resembling closely the natural process of respiration, which is one of expansion from without inwards, and not, as when the mouth or bellows are used, of pressure from within outwards. In one case the lungs are, as it were, drawn outwards, the air merely rushing in to fill up the vacuum that would otherwise be produced within the thorax by the expansion of its parietes; in the other they are forcibly pressed upon from within, and hence there is danger of rupture of the air-cells. The inflation of the lungs with oxygen gas is likely to be of great service in extreme cases of asphyxia. I have found by experiment that the contractions of the heart can be excited by inflating the lungs with this gas, when the introduction of atmospheric air fails in doing so, and there are cases on record in which resuscitation was effected by inflating the lungs with oxygen gas, when in all probability it could not have been effected with any other means. In my Essay on Asphyxia will be found a case of resuscitation, in which oxygen was successfully employed by Mr. AVeekes after the asphyxia had continued three quarters of an hour. Whatever means of resuscitation are adopted they should be continued for at least three or four hours, even though no signs of life show themselves; and after resuscitation the patient should be kept quiet in bed for some hours. The danger of the supervention of secondary asphyxia after recovery has apparently taken place, is much increased, and indeed is usually brought about by some effort on the part of the patient that tends to embarrass the partially restored action of the heart and lungs. The patient being to all appearances resuscitated is allowed to get up and walk home, when the symptoms of asphyxia speedily return. Should symptoms of secondary asphyxia, such as stupor, laborious respiration, dilatation of the pupils, and convulsions, manifest them- selves, artificial respiration should be immediately set up, and be maintained until the action of the heart has been fully restored. In these cases I should, from the very great efficacy of electricity, in the somewhat similar condition resulting from the administration of the narcotic poisons, be disposed to recom- mend slight shocks to be passed through the base of the brain and upper portion of the spinal cord, so as to stimulate the respiratory tracts. Asphyxia from the respiration of noxious gases, such as carbonic acid, is best treated by exposing the surface of the body to cold air, by dashing cold water upon the face, and by setting up artificial respiration without delay, if the impression of cold upon the surface does not excite these actions. There is a peculiar variety of this kind of asphyxia, that is occasionally met with among infants, the true nature of which was pointed out to me by Mr. Wakley, who, as coroner, has had abundant opportunities of witnessing it, as it is not an uncommon cause of accidental death amongst the children of the poor. It is that condition in which a child is said to have been overlaid; the child tieeping with its mother or nurse being found in the morning suffocated in the 312 INJURIES OF THE THROAT. bed. On examination no marks of pressure will be found, but the right cavities of the heart and lungs are gorged with blood, and the surface livid, clearly indicating death by asphyxia. That this accident is not the result of the mother overlaying her child, is not only evident from the post mortem appearances, but was clearly proved by a melancholy case to which I was called a few years ago, in which a mother, on waking in the morning, found her twin infants lying dead on either side of her. Here it was evident from the position of the bodies that she could not have overlaid both. The true cause of death in these cases is the inhalation of, and slow suffocation by, the vitiated air which accumulates under the bed-clothes that have been drawn, for the sake of warmth, over the child's head. In such cases as these, resuscitation by artificial respiration should always be attempted if any signs of life be left. In cases of hanging, death seldom results from pure asphyxia, but is usually the consequence, to a certain degree at least, of apoplexy, and commonly of simultaneous injury of the spinal cord. In these cases, bleeding from the jugular vein may be conjoined with artificial respiration. If there should be a difficulty in setting up artificial respiration, through the mouth or nose, as is more especially likely to happen when the patient has been suffocated by breathing noxious gases, or in cases of hanging, tracheotomy or laryngotomy should at once be performed, and the lungs inflated through the opening thus made in the neck. FOREIGN BODIES IN THE AIR-PASSAGES. Though the introduction of foreign bodies into the air-passages is not a very common accident, yet a great variety of substances that admit of being swallowed has been found there : such as nut-shells, beans, cherry-stones, teeth, meat, money, buttons, pins, fish-bones, bullets, pills, pebbles, and pieces of stick. These foreign bodies are not introduced into the air-passages by any effort of deglutition, for no substance can be swallowed through the glottis; but if a person, whilst swallowing or holding any substance in his mouth makes a sudden inspiration, the current of air may draw it between the dilated lips of the glottis into the larynx. The symptoms vary, according to the situation in which the foreign body is lodged, its nature and the period that has elapsed since the occurrence of the accident. The foreign body may lodge in one of the ventricles of the larynx, or, if light, it may float in the trachea, carried up and down by the movement of the air in expiration and inspiration. If too heavy for this, it will fall into one or other of the primary divisions of the trachea, and, as Aston Key has observed, will most commonly be found in the right bronchus, this being larger, and in a more direct line with the trachea than the left. If the substance be small, it may pass into one of the secondary divisions of the bronchi, and if it continue to be lodged here for a sufficient length of time, may make a kind of cavity for itself in the substance of the lung, where it may either lie in an abscess, or become encysted. The symptoms may be divided into three stages. 1st. Those that immediately follow the introduction of the substance. 2d. Those produced by the irritation of its presence; and 3d. Symptoms of an inflammatory character coming on at a later period. 1st. The immediate symptoms vary somewhat, according to the size and nature of the body, and the part of the air-tube that it reaches. In all cases thece is a feeling of intense suffocation, with great difficulty of breathing, and violent fits of spasmodic coughing, often attended by vomiting; during which the foreign body may be expelled. Indeed, its partial entry and immediate extrusion, by coughing, is not uncommon. In some cases immediate death may ensue at this period. If it have entered the air-passages fully, there is usually FOREIGN BODIES IN THE AIR-PASSAGES. 313 violent coughing with feeling of suffocation for an hour or two, accompanied by lividity of the face, great anxiety, and sense of impending death. There is also usually pain felt about the episternal notch. These symptoms then gradually subside, but any movement on the part of the patient brings them on again with renewed violence. All these symptoms are most severe if the foreign body remains in the larynx; the voice being then croupy, irregular in tone, or lost. If it be lodged elsewhere, so often as it is coughed up, and strikes against the interior of the larynx, an intense feeling of suffocation is produced; and if it happen to become impacted there, sudden death may result, even though it be not of sufficient size to block up the air-passage, but apparently by the spasm that is induced. Some years ago a boy died at the Westminster Hospital before tracheotomy could be performed, in consequence of a flat piece of walnut-shell that had got into the trachea being suddenly coughed up, and becoming impacted in one of the ventricles of the larynx. The symptoms, during this period, are much less severe when the foreign body is in the trachea or bronchi. 2nd. When the foreign body has passed into the air-passages, and the imme- diate effects produced by its introduction have been got over, another set of symptoms, dependent on the irritation produced by it, is met with; and it is during the occurrence of these that the patient is most generally brought under the surgeon's observation. These symptoms are of two kinds; general and auscultatory. The general symptoms consist of occasional fits of spasmodic cough, accom- panied by much difficulty of breathing, a feeling of suffocation, and an appear- ance of urgent distress in the countenance. These attacks do not occur when the.patient is tranquil, but come on whenever the foreign body is coughed up so as to strike the larynx, and the upper and more sensitive parts of the air- E>assages. As a general rule the distress is less, the lower the substance is odged; the sensibility of the inferior portion of the trachea and bronchi being much less acute than that of the larynx and the upper part of the trachea. In consequence of the irritation, there is usually abundant expectoration of frothy mucus. The auscultatory signs depend necessarily upon the situation of the foreign body. If this be loose and floating, it may be heard on applying the ear to the chest, moving up and down, and occasionally striking against the side of the trachea. If it be fixed, it will necessarily give rise to a certain degree of ob- struction to the admission of the air beyond it, perhaps occasioning bruits during its passage. If it be impacted in the larynx, the voice will be hoarse and croupy, and there will be a loud rough sound in respiration, with much spasmodic cough and distress in breathing. If it be impacted in one bronchus, the respi- ratory murmur will be much diminished, or even absent, in the corresponding lung, and probably puerile in the other; whilst percussion will yield an equally clear and sonorous sound on both sides of the chest, air being contained in the lung of the obstructed side, but not readily passing in and out. If one of the subdivisions of either bronchus be occupied by the foreign body, the entrance of air will be prevented in the corresponding lobe of that lung, though it enter freely every other part of the chest. If the foreign body be angular, or perfo- rated, peculiar sibilant and whistling noises may be heard as the air passes over and through it. 3rd. After a foreign body has been lodged for a day or two, symptoms of inflammation of the bronchi, or lungs, are apt to be set up; in some cases, how- ever, these only oocur after a considerable time has elapsed, or, perhaps, not at all, much depending, of course, on the shape and character of the irritant. If it continue to lodge, it generally forms for itself a cavity in the substance of the lung, whence purulent and bloody matters are continually expectorated, until the patient dies in the course of a few months, or a year or two, of phthisis. It has occasionally happened, however, that the substance has been coughed up 314 INJURIES OF THE THROAT. after a very long lodgment, the patient recovering. Thus, Tulpius relates a case in which a nut-shell was coughed up after being lodged for seven years, and Heckster one in which a ducat was thus brought up after a lapse of two years and a half, the patient, in both instances recovering. In other cases again death may ensue, although the foreign body is coughed up; thus, Sue relates an in- stance in which a pigeon-bone was spat up seventeen years after its introduction, the patient, however, dying in little more than a year from marasmus. The prognosis depends more upon the nature of the foreign body and its size than on any other circumstances. If it be rough, angular, and hard, there is necessarily much more risk than if it be soluble in, or capable of disintegration by, the mucus of the air-passages. So long as the foreign body is allowed to remain in, the patient is in imminent danger, either from immediate and sudden suffocation, or from inflammation at a more remote period. The danger depends greatly upon the length of time that it is allowed to lodge. Of 58 cases (4 of which have fallen under my own observation, the remaining 54 being collected from various sources, and constituting all those that I have been able to find recorded) I find the time that the foreign body was allowed to remain in, and the result of the case stated in 45 instances, which I have tabulated as follows: PERIOD THAT IT REMAINED IN. NUMBEROF CASES. RECO-VERED. DIED. 7 4 12 8 3 4 7 5 3 5 4 3 2 4 2 1 7 4 0 2 3 Between 1 month and 3 mouths..... Total........................ 45 26 19 From this it would appear that if the patient escaped the danger of the im- mediate introduction, the greatest risk occurred between the second day and the end of the first month, no less than 11 patients out of 20 dying during this period, and then that the mortality diminished until the third month, from which time it increased again. The cause of death also varies according to the period at which the fatal result takes place. During the first twenty-four, and indeed, forty-eight hours, it happens from convulsions and sudden asphyxia. During the first few weeks it is apt to occur from inflammatory mischief within the chest, and after some months have elapsed the patient will be carried off by marasmus or phthisis. Spontaneous expulsion of the foreign body, usually in a violent fit of coughing, occasionally occurs. Dr. Cross finds that there are 49 cases on record, in which the body was spontaneously expelled, the patient recovering. Of these, in 37 it was expelled during a fit of coughing. The period during which a foreign substance may remain in the air-passages before it is spontaneously expelled, varies from a few minutes to many months or years; in one case, a piece of bone introduced at the age of three, was not ejected until sixty years had elapsed. In 8 cases death followed the spontaneous expulsion. Treatment. — This accident is always a very serious one, and hence requires prompt and energetic means to be used in order to save the patient; and for- tunately the means at our disposal, consisting of the simple operation of opening the trachea, and thus facilitating the expulsion of the foreign body, are usually highly successful. I find that of 56 cases in which the result was noted, 33 lived, FOREIGN BODIES IN THE AIR-PASSAGES. 315 and 23 died; but on analyzing these cases more closely, it appears that in 36 no operation was performed; the expulsion of the foreign body being trusted to the efforts of nature. Of these 20 died, and 16 lived. In the remaining 20 cases, tabulated below, tracheotomy was performed; of these 17 lived, and only 3 died, showing a remarkable success attendant on this operation. PERIOD THAT IT REMAINED IN. NUMBER OF CASES. CURED. DIED. 3 2 8 5 2 2 2 7 4 2 1 0 1 1 0 20 17 3 Dr. Gross has since extended these statistics very materially, and has found that out of 68 recorded cases in which tracheotomy has been performed, the operation was successful in 60, and in 8 the patient died. Laryngo-tracheotomy was done in 13 cases; of these, 10 successes, and 3 deaths. No means short of operation have been found of any use. Emetics, sternu- tations, inversion, and succussion of the body, are all either useless or dan- gerous, unless the air-passages have previously been opened. If, therefore, a patient is seen a few hours, days, or weeks, after a foreign body has been introduced into the air-passages, or indeed at any period after the accident, tracheotomy ought to be performed. But it may be asked, for what purpose is the trachea opened ? Why should not the foreign body be expelled through the same aperture by which it has entered ? The opening in the trachea performs a double purpose; it not only serves as a ready and passive outlet for the expulsion of the foreign body, but also as a second breathing aper- ture in the event of its escaping through the glottis. The advantage of the opening in the trachea as a ready aperture of expulsion is evident, from the fact that of 14 of the operated cases in which it is stated how the foreign body was expelled, I find that in 12 it was ejected through the artificial opening, whilst in 2 only did it pass out through the glottis. The reason why the foreign body usually passes out of the artificial opening in preference to escaping by the glottis, is, that the sides of one aperture are passive, whereas those of the other are highly sensitive and contractile. Before the operation is performed, it will be found that the great obstacle to expulsion is not only the sensitiveness of the larynx, great irritation being induced when it is touched from within, but also the contraction of the glottis, by the closure of which not only is the expulsion of the foreign body prevented, but respiration impeded. Every time the foreign body is coughed up so as to touch the inte- rior of the larynx, intense dyspnoea will be produced, owing to sudden and involuntary closure of the glottis, by which respiration is entirely prevented and suffocation threatened; the expulsion of the body is consequently arrested, unless it were by chance to take the glottis by surprise, and pass through it at once in the same way that it has entered it, without touching its sides. If there is a second breathing aperture, though the larynx is equally irritated by the foreign body, yet this dyspnoea cannot occur, respiration being carried on uninterruptedly by one opening whilst the foreign body escapes through the other; and thus, under these circumstances, it may pass through the glottis with but little inconvenience to the patient. In some cases the foreign body is expelled at once after the trachea has been 316 INJURIES OF THE THROAT. opened; in others, not until some hours, days, or even weeks, have elapsed Thus, in Houston's case, a piece of stick was not coughed up until ninety-seven days after the operation; and in Brodie's case, sixteen days elapsed before the half-sovereign came away. In some cases laryngotomy has been performed instead of tracheotomy, and the foreign body has been equally well expelled. Dr. Gross gives 13 instances of this successful in their results, and 4 in which death followed the operation. The expulsion has in some instances been facilitated by inverting the patient, shaking him, or striking him on the back. In cases in which the foreign body is not readily expelled, it has been proposed to introduce forceps and extract it. But although in some instances it has succeeded, the uncertainty and danger of such a proceeding is so great that few surgeons would be disposed to attempt it. The introduction of the forceps producing violent irritating cough, during which their points might readily be driven through the bronchi, and thus wound the lung or contiguous important structures. Besides this, there would be the danger of seizing the projecting angle at the bifurcation of the bronchi instead of the foreign body, and thus injuring the parts seriously. If the foreign body is fixed, the safer plan would certainly be to leave the aperture in the trachea unclosed, and wait for the loosening of the body, and its ultimate expulsion, which have hitherto occurred in all cases that have been operated on, or its escape might be facilitated by the gentle introduction of a probe, so as to dislodge it if seated in either bronchus, though this should be done with great caution, or the patient may be inverted and succussed when the expulsion may take place. Should it not then escape the wound should be kept open by means of blunt hooks, when, perhaps, it may be ejected. x\ntiphlogistic treatment must be continued during the whole progress of the case. After the escape of the foreign body the opening in the trachea must be closed. Dr. Gross' statistics are as follows: — of 159 cases spontaneous expulsion took place in 57; of these 49 recovered and 8 died. Inversion of the body alone was successful in 5 cases. Laryngotomy was practised in 17; of these 13 lived and 4 died. Tracheotomy in 68; of these 60 lived and 8 died. Laryngo-tracheotomy in 13; of these 10 lived and 3 died. Scalds of the mouth, the pharynx, and the glottis, occasionally occur from attempts to swallow boiling water; or these parts are scorched by the inha- lation of flame. The scalding of these parts chiefly happens to the children of the poor, who being in the habit of drinking cold water from the spout of a kettle, inadvertently attempt to take a draught from the same source when the water is boiling. The hot liquid is not swallowed, but though immediately ejected, has scalded the inside of the mouth and pharynx, giving rise to a con- siderable degree of inflammation, which, extending to the glottis, may produce oedema of it, and thus speedily destroy life by suffocation. In 3 cases which I have had an opportunity of examining after death, there was no sign of in- flammation below the glottis, though the lips of this aperture were greatly swollen; and this I believe to be invariably the case, the inflammation not ex- tending into the interior of the larynx, as has been pointed out by Dr. M. Hall. The accident always reveals itself by very evident signs; the interior of the mouth looks white and scalded, the child complains of great pain, and difficulty of breathing soon sets in; which, unless efficiently relieved, may terminate in speedy suffocation. In those cases in which these parts have been similarly injured by the flame produced by the explosion of gas or of fire-damp being sucked into the mouth, the same conditions present themselves. In the treatment of this injury the main point to attend to is to subdue the inflammation, before it involves the glottis to a dangerous extent. With this INJURIES OF THE "(ESOPHAGUS, 317 view, leeches should be freely applied to the neck, and calomel with antimony administered. If symptoms of urgent dyspnoea have set in, tracheotomy must be performed without delay, and if the child be not too young, a tube introduced into the aperture so made, and kept there until the swelling about the glottis has been subdued by a continuance of the antiphlogistic treatment. In the majority of the cases, however, that have fallen under my observation, in which this operation has been performed, the issue has been a fatal one, from the speedy supervention of broncho-pneumonia; but as it affords the only chance of life when the dyspnoea is urgent, it must be done, though its performance in very young children is often attended by much difficulty, from the shortness of the neck and the small size of the trachea. INJURIES OF THE OESOPHAGUS. Wounds of the oesophagus are chiefly met with in cases of cut throat, in which, as has been already stated in treating of these injuries, they occasion much difficulty by interfering with deglutition. Foreign bodies not uncommonly become impacted in the pharynx and oeso- phagus, and may produce great inconvenience by their size or shape. If large, as a piece of money or a lump of meat, it may become fixed in the lower part of the pharynx or the commencement of the oesophagus, which is narrowed by the projection of the larynx backwards, and, compressing or occluding the ori- fice of the glottis, may asphyxiate the patient at once. If the foreign body get beyond this point, it usually becomes arrested near the termination of the oeso- phagus. When it is small, or pointed, like a fish-bone, pin, or bristle, it usually becomes entangled in the folds of mucous membrane that stretch from the root of the tongue to the epiglottis, or that lie along the sides of the pharynx. In some cases it may even perforate these, penetrating the substance of the larynx, and thus producing intense local irritation. The symptoms occasioned by the impaction of a foreign body in the food-pas- sages are sufficiently evident. The sensations of the patient, who usually com- plains of uneasiness about the top of the sternum; the difficulty that he has in swallowing solids, and perhaps the occurrence of an urgent sense of suffocation, lead to the detection of the accident. Should any doubt exist, the surgeon may, by introducing his finger, explore nearly the whole of the pharynx, and should examine the oesophagus by the cautious introduction of a well-oiled probang. If the impaction is allowed to continue unrelieved, not only may deglutition and respiration be seriously interfered with, but ulceration of the oesophagus will take place, and abscess form either behind or between it and the trachea, or fatal hemorrhage may ensue. It may happen that the foreign body, by transfixing the coats of the oesopha- gus, has seriously injured some neighboring parts of importance. Thus, in a curious case admitted into the University College Hospital, a juggler, in attempt- ing to swallow a blunted sword, perforated the oesophagus and wounded the pericardium, death consequently resulting in the course of a few days. The treatment must depend upon the nature of the foreign body and its situa- tion. Should it be of large size, blocking up the pharynx so as to render respi- ration impracticable, it may be hooked out with the surgeon's fingers. Should asphyxia have been induced, it may be necessary to perform tracheotomy at once, and to keep up artificial respiration until the foreign body can be extracted. If it be small, or pointed, as a fish-bone or pin for instance, though it have lodged high up, the surgeon will usually experience great difficulty in its removal, as it gets entangled between and is covered in by the folds of the mucous membrane, where from its small size it may escape detection; and after it has been removed, the patient will experience for some time a pricking sen- 318 INJURIES OF THE CHEST. sation, as if it were still fixed. If the impacted body have got low down into the oesophagus, the surgeon must deal with it according to its nature. If smooth and soft, as a piece of meat for instance, it may be pushed down into the throat by the gentle pressure of the probang. If, however, it be rough, hard, or sharp pointed, as a piece of earthenware or bone, such a procedure would certainly cause perforation of the oesophagus, and serious mischief to the parts around • under these circumstances, therefore, an attempt at extraction should be made by means of long slightly curved forceps, constructed for the purpose. It occasionally happens that the foreign body has become so firmly impacted in the pharynx or oesophagus that it cannot be extracted with any degree of force that it is prudent to use; under these circumstances it may become neces- sary to open the tube and thus remove it. The operation of Pharyngotomy or (Esophagotomy is, however, seldom called for, but if required may be performed by making an incision about four inches in length along the anterior border of the sterno-mastoid muscle on the left side of the neck, the oesophagus naturally curving somewhat towards this side. The dissection must then be carried with great caution between the carotid sheath and the larynx and trachea in a direc- tion backwards, the omo-hyoid muscle having been divided in order to afford room. Care must be taken in prosecuting this deep dissection not to wound either of the thyroid arteries, more especially the inferior one, which will be endangered by carrying the incisions too low. When the pharynx or oesophagus has been reached, a sound or catheter should be passed through the mouth into this cavity, and pushed forwards so that its point may cause the walls to project, and thus serve as a guide to the surgeon. This must then be cut open, and the aperture thus made in the gullet enlarged by means of a probe-pointed bistoury, to a sufficient size, for the extraneous substance to be extracted. CHAPTER XX. INJURIES OF THE CHEST. Wounds of the chest derive their principal interest and importance from the concomitant injury of the lungs, heart, or larger blood-vessels. When the parietes alone are wounded, the injury differs in nothing from similar lesions in other parts of the body. In these cases if the surgeon be in doubt whether the cavity of the chest has been penetrated or not, it is better for him to wait and to be guided in his opinion by the symptoms that manifest themselves, rather than by probing the wound, running the risk of converting it into what he dreads, a penetrating wound of the chest. Wound of the lung is the most common and one of the most serious compli- cations of injuries of the chest. It may occur without any external wound, from the ends of a broken rib being driven inwards upon this organ: most frequently, however, it happens from a penetrating wound of the chest, by stab or bullet The symptoms of this injury are sufficiently well marked. There is in the first place the immediate shock to the system that usually accompanies the infliction of a severe injury, the patient at the same time being seized with considerable difficulty of breathing, followed by much tickling and irritating cough, and the expectoration of frothy bloody mucus, or perhaps of large quan- tities of pure blood. If there be an external opening, the air may pass in and EMPHYSEMA. 319 out during the act of breathing, and emphysema, pneumo-thorax, or pneu- monia will speedily supervene. On auscultating the chest immediately after the infliction of the injury, and before there is time for the supervention of any after-consequences, a loud rough crepitation will be distinctly audible at and around the seat of injury. The principal dangers attending a wound of the lung arise from the bleeding, both external and internal, the occurrence of emphysema, pneumo-thorax, pneumonia, and empyema. 1st. The hemorrhage is usually abundant and often fatal, the patient spitting up a large quantity of florid, frothy blood. If it do not prove fatal in the early period of the injury, this bloody expectoration generally ceases in a great measure in the course of forty-eight hours, giving way to sputa of a more rusty character. If the external wound be very free, there may also be copious bleeding from it, but not unfrequently the blood finds its way into the pleural sac, rather than through the external aperture, and accumulating in it, may induce death, either by this internal and concealed hemorrhage, or by occa- sioning suffocation. The symptoms of this internal hemorrhage, Hemothorax, are those that generally characterize loss of blood, such as coldness and pallor of the surface, small weak pulse, and a tendency to collapse with increasing dyspnoea. The more special signs consist in an inability to lie on the uninjured side, with, in extreme cases, some bulging of the intercostal spaces, and an ecchymosed condition of the posterior part of the wounded side of the chest. The most important signs, however, are those that are furnished by ausculta- tion. As the blood gravitates towards the back of the chest, between the posterior wall and the diaphragm, there will be gradually increasing dulness on percussion in this situation, with absence of respiratory murmur; the other portions of the lung, however, admitting air freely. 2d. Emphysema, or the infiltration of air into the cellular tissue of the body, and pneumo-thorax, or the accumulation of air in the cavity of the pleura, are not unfrequent complications of wounded lung, although not by any means invariably met with. These accidents more commonly occur when the external wound is small and oblique, than when it is large and direct, and not unfre- quently happen in those cases in which the lung is punctured by a fractured rib, without there being any external wound. In the majority of cases, emphy- sema and pneumo-thorax occur together, but either may be met with separately. The mechanism of traumatic emphysema is most commonly as follows: The pleura costalis being wounded and the lung injured, at every inspiration a quantity of air is sucked into the pleural sac, either through the external wound, or, if none exist, from the hole in the lung, thus giving rise to pneumo- thorax. At every expiration, the air that thus accumulates in the pleural sac being compressed by the descent of the walls of the chest, is pumped into the cellular tissue around the edges of the wound; and if this be oblique and valvular, being unable to escape wholly through it, finds its way at each suc- ceeding respiration further into the large cellular planes, first about the trunk and neck, and eventually, perhaps, into those of the body generally. Though this is the way in which emphysema usually occurs, it may be occasioned other- wise. Thus, for instance, I had lately under my care a woman who had exten- sive emphysema of the cellular tissue of the trunk from fractured ribs, but without any pneumo-thorax, the lung having been wounded at a spot where it was attached to the walls of the chest by old adhesions, and the air having passed through them into the cellular tissue of the body, without first entering the cavity of the pleura. Mr. Hilton has described a form of traumatic eni- physema that arises by the rupture of an air-cell or bronchus without any external wound. The air, getting into the posterior mediastinum, and, finding its way along the nerves and vessels in this situation, passes out through the cervical fascia, which closes the upper part of the thorax, and thus reaching 320 INJURIES OF THE CHEST. the neck, diffuses itself along the sheaths of the arteries and nerves, along which it finds its way into the limbs; its appearance in which is first indicated by its extending along the course of the vessels. The symptoms of emphysema are very distinctly marked. There is a puffy swelling, pale, and crackling when pressed upon, at first confined to the neigh- borhood of the wound, if there be one externally; if not, making its appearance opposite the fractured ribs, and gradually extending over the upper part of the trunk and neck, to which it is usually limited; in some cases, however, which are happily rare, the swelling becomes more general, the body being blown up to an enormous size, the features effaced, the movement of the limbs interfered with, respiration arrested, and suffocation consequently induced; after death air has been found in all the tissues, even under the serous coverings of the abdominal organs. In traumatic pneumo-thorax there is a diminution or complete absence of the respiratory murmur on the affected side, with a loud tympanitic resonance on percussion, puerile respiration in the sound lung, and considerable distress in breathing. 3d. Pneumonia is an invariable sequence of a wounded lung, and constitutes one of the great secondary dangers of these injuries; the inflammation that is necessary for the repair of the wound in this organ having frequently a tendency to extend beyond the part injured, and not uncommonly to terminate in abscess. Traumatic pneumonia resembles in all its symptoms, auscultatory as well as general, the idiopathic form of the disease. There is the same crepitation, dulness on percussion, and absence of respiratory murmur as hepa- tization advances; with rusty sputa, much tinged with blood in the early stages. It differs, however, from the idiopathic form of the disease, in having a less tendency to diffuse itself throughout the lung, in being limited to the injured side alone, and in more frequently terminating in abscess, which, however, is often dependent on the lodgment of some foreign body, such as a piece of wadding or clothing, in the substance of the organ. 4th. Empyema comes on at a later period, being usually occasioned by the irritation of effused blood, or of some extraneous substance that has lodged in the pleura. Its existence may be recognized by dulness on percussion, and absence of respiratory murmur at the lower and posterior parts of the chest up to a level that has a gradual tendency to ascend, and that varies according as the patient is upright or recumbent, until at last the whole side of the chest being filled with pus, there is increase of its size on measurement, with bulging of the intercostal spaces, and compression of the lung against the spine. The prognosis in wounds of the lungs is of course extremely unfavorable, but less so than that of similar injuries of most of the other viscera. Gun-shot wounds of the chest are more dangerous than stabs, owing partly to the lacera- tion attendant on a bullet-wound, but chiefly perhaps on the lodgment of foreign bodies that so commonly occurs in these injuries. Guthrie states, that more than half of those who are shot through the chest, die. After the battle of Toulouse, of 106 such cases, nearly half died; and of 40 cases at the Hotel Dieu, 20 died. Messrs. Mouat and Wyatt state that of 200 cases of penetrating rounds of the chest occurring in the Bussian army at the siege of Sebastopol, and treated at Simpheropol, only 3 recovered. The Russian surgeons, however, do not bleed in these cases, but use digitalis instead. The great danger and principal cause of death in these injuries is unquestionably the hemorrhage that ensues. This may prove immediately fatal if one of the larger pulmonary ves- sels is divided. As the bleeding is most abundant at, and shortly after the receipt of the wound, Hennen states that if the patient survive the third day, great hopes may be entertained of his recovery. After this period the chief source of danger is the occurrence of inflammation of the lungs and pleura, the extent and severity of which are greatly increased in gun-shot injuries by the frequent lodgment of foreign bodies within the chest. Emphysema is seldom TREATMENT OF WOUNDS OF THE CHEST. 321 a dangerous complication, though it may become so if very extensive, and allowed to increase unchecked. If both lungs are wounded at the same time, the result is almost inevitably fatal, either by the abundant hemorrhage suffocating or exhausting the patient; or else by the induction of asphyxia in consequence of air being drawn into both the pleural sacs, and thus by compressing the lungs, arresting respiration. This, however, does not necessarily result, and there are a sufficient number of cases on record of recoveries after stab or bullet wounds traversing both sides of the chest, to show that collapse of the lungs and consequent asphyxia does not necessarily result from this double injury, which indeed has also been deter- mined experimentally on animals by Cruveilhier. The treatment of wounds of the chest, implicating the lungs, must have reference to the various sources of danger that have just been indicated. The local treatment is of a very simple character. If the wound have been made by a bullet, all foreign bodies that are within reach should be extracted. If there is any difficulty in doing this, it may be necessary to enlarge the aper- ture and then to remove them; but the surgeon must not go too deeply or per- severingly in search of them, lest he excite more irritation than the foreign body would. Light water-dressing should then be applied, no attempt being made to close the aperture, so that the escape of any extraneous substance that may have been left, or of extravasated blood, may not be interfered with. If the wound be a clean puncture, the edges may be brought together and closed by means of stitches, plasters, and collodion, so that the bleeding may be arrested, and the patient enabled to breathe with more ease. It is seldom that there is any troublesome hemorrhage from wounds of the intercostal arteries; should there be so, the surgeon must enlarge the orifice of the wound, and secure the bleeding vessel in the best way he can. Wounds of the internal mammary artery are of rare occurrence, considering its exposed situation. They may however occur if the chest is penetrated in front through the intercostal spaces, or costal cartilages. The danger in these cases is from the hemorrhage taking place slowly into the anterior mediastinum, or one of the pleurae, without any external bleeding revealing the mischief that is going on within. If the wound of the vessel be ascertained, an attempt should be made, by enlarging the external aperture, to seize and ligature the bleeding ends, cutting directly down upon them through the injured intercostal space, or the vessel might even be followed beneath one of the costal cartilages, if necessary, by cutting through this. Should much blood have already been extravasated, this must be removed through the external wound, by the intro- duction of a female catheter, or by the application of a cupping-glass over it, and the case then treated like one of effusion into the chest. In the constitutional treatment of these injuries, the first indication consists in diminishing the quantity of blood circulating through the lungs, and thus endeavoring to arrest the hemorrhage from these organs. With this view, a free venesection, to the extent of from at least twenty to thirty ounces, or even more, must be practised. In this way the bleeding may be stopped at once; should it recur, and the pulse rise, blood must be taken from the arm again and again. The most experienced surgeons are unanimous in their opinion, that at this stage of the injury, the patient's safety lies in free and repeated venesec- tion. The patient must then be kept lying on the injured side, and have nothing but ice or barley-water allowed. If the patient survive the third day, the danger to be apprehended is from inflammation within the chest. Here also bleeding must be practised, though it need not be done to the same extent as in the earlier stages of the injury. The inflammation must also be combated by a rigid diet, and by the administra- tion of antimonials. In fracture of the ribs with wounded lung, the same line 322 INJURIES OF THE CHEST. of treatment requires to be adopted, but when the accident occurs in elderly people, we may advantageously substitute calomel and opium for the antimonials If extravasation of blood into the pleura is going on, its farther effusion must, if possible, be arrested by the same means that are adopted for the stoppage of external hemorrhage. When the bleeding has been checked in this way, the blood must early be let out from the pleural sac; for, if it be allowed to remain there, it will speedily putrefy, giving rise to extensive formations of pus in this cavity. In order to prevent these occurrences, the wound.should be opened freely with a probe-pointed bistoury, on the fifth or sixth day after the injury, so that the blood may be discharged. If it do not readily come away, a cup- ping glass may be applied over the aperture, and thus it may be withdrawn. Should, however, the hemorrhage continue notwithstanding the employment of the means indicated, Guthrie advises that the wound should be closed, so that the blood that flows into the pleural sac may, by accumulating in this, compress the lungs, and thus arrest the further escape of blood from the wounded ves- sels; the patient at the same time should be made to lie on the injured side, in order to increase the pressure exercised upon the wounded and bleeding organ. On the sixth or eighth day the chest should be tapped, or the wound opened again, in order to evacuate the extravasation, and prevent its acting as an irri- tant to the pleura; or by permanently compressing and condensing the lung, rendering this useless. In all cases of purulent effusion into the chest, Guthrie advises, with good reason, that tapping should be early performed, in order that the lung may not be bound down by false membranes, and consequently being unable to expand, lead to permanent flattening of the side, and impairment of respiration. If any extraneous body, such as a bullet, a piece of wadding, or of clothing, have penetrated too deeply into the chest to be readily extracted through the external wound, it would not be safe to make incisions or exploratory researches, with a view of extracting it; for, though its presence would increase the patient's danger, yet, attempts at extraction would not only add to this, but in all proba- bility be fatal. In many cases, bodies so lodged form an abscess around them, are loosened, and eventually are spit up, or appear at the external wound. In others, again, they remain permanently fixed in the chest, becoming enveloped in a cyst, and so remaining for years, without producing irritation. In this way Hennen states that a bullet has been lodged in the chest for upwards of twenty years; and Vidal mentions a man who lived for fifteen years with the broken end of a foil in his chest, which, after death, was found sticking in the verte- brae, and stretching across to one of the ribs. The treatment of emphysema consists of little in addition to what is called for by the wounded lung. In many cases, indeed, the air becomes rapidly absorbed, without the necessity of any local interference. In others, again, the pressure of a bandage may be required. If, however, the emphysema be so extensive as to interfere with respiration, the external wound must be freely opened, and scarification made into the cellular tissue, so as to give exit to the air. HERNIA OF THE LUNG, OR PNEUMOCELE. Hernia of the lung is an affection of extremely rare occurrence. It consists in the protrusion of a portion of this organ at some part of the thoracic walls ■so as to form a tumor under the skin. It has most frequently been met with after an external wound, under the cicatrix of which the hernial swelling has appeared; but it has been known to occur from fractured ribs without any wound, and even from violent straining during labor. In these cases it is pro- bable that the intercostal muscles and costal pleura having been divided or rup- tured by the efforts of the patient, and not having united afterwards, the lung WOUNDS OF HEART AND LARGE VESSELS. 323 has, during expiration, gradually insinuated itself into the aperture so formed, until at last the hernial tumor appeared. This protrusion may take place at any part of the thoracic parietes: thus Velpeau has observed it in the supra-clavicular region of a girl; but most com- monly it occurs on one or other side of the chest. The tumor may attain a large size; I have heard Velpeau state that he has seen one, half as large as the head. It does not appear to shorten life. The only case that has fallen under my observation is one that I saw in 1839, in Velpeau's wards at La Charite: and, as the signs of the affection were well marked in this case I may briefly relate it, from notes taken at the time. A man twenty-nine years of age, left-handed, received in a duel, a sword wound at the inner side of, and a little below the left nipple; he lost a considerable quantity of blood, but did not spit up any, the wound healed in about a fort- night, shortly after which he found the tumor, for which he was admitted three months and a half after the receipt of the injury. On examination, an indu- rated cicatrix about half an inch in length was found a little below, and to the inner side of the left nipple. On aspiring or coughing, a soft tumor about the size of an egg appears immediately underneath the cicatrix, which it raises up; it subsides under pressure, or when the patient ceases to inspire or to cough; and its protrusion may be prevented by pressing the finger firmly on the part where it appears, when a depression is felt in the intercostal muscles. If the fingers are slid obliquely over the tumor, it yields a fine and distinct crepitation, exactly resembling that produced by compressing a healthy lung, and the spongy tissue of the organ can be distinguished. On applying the ear a fine crackling and rubbing sound is distinctly perceived; it is resonant on percussion. The portion of protruded lung does not appear to re-enter the chest on inspiration, but is firmly fixed in its new situation. No treatment was adopted in the case, nor does any appear admissible in similar ones. The only affection with which a hernia of the lung can be confounded is a circumscribed empyema which is making its way through the walls of the chest. Here, however, the dulness on percussion, the absence of respiratory murmur, and of crackling under the fingers, will readily enable the surgeon to make the diagnosis. It occasionally happens in extensive wounds of the chest that a portion of the lung protrudes during efforts at expiration. If the wound be free, the protruded lung may return on pressure, or during inspiration. If left unreturned, it soon becomes livid and gangrenous; under these circumstances it may be re- moved by the knife or ligature; but Guthrie advises that the protruded part should never be separated from the pleura costalis by which it is surrounded at its base, so that the cavity of the thorax may not be opened; the wound must then be closed in the usual way. WOUNDS OF THE HEART AND LARGE VESSELS. These injuries are generally immediately fatal from the sudden loss of blood and the nervous shock that the patient sustains. There are many cases on record, however, of persons that have walked or run some considerable distance after receiving a wound in the heart, before falling down dead. Olivier and Sanson have collected 29 cases of penetrating wounds of the heart that did not prove fatal in the first forty-eight hours after the receipt of the injury. On analyzing these, it would appear that the rapidity of death depends greatly on the direction of the wound and the part of the organ injured. When the wound is parallel to the axis of the heart it is not so speedily fatal as when in a transverse direction, and wounds of the auricle are more immediately followed by death than those of the ventricle; the irregular contraction of the different planes of muscular fibre that enter into the formation of the wall of the ven- 324 INJURIES OF THE CHEST. tricle tending to obstruct the free passage of the blood through the wound, and perhaps to close it entirely. The size of the wound, however, will necessarily influence the result more materially than its direction. Without referring to numerous cases recorded by the older surgeons, there are a sufficient number of instances reported by modern writers to prove that an individual may live for many days, and even recover altogether from the effects of a wound by which the cavities of the heart have been penetrated, although with a foreign body lodged in them. Thus Ferrus relates the case of a man who lived for twenty days with a skewer traversing the heart from side to side. Messrs. Davis and Steward found a piece of wood, three inches long, in the right ven- tricle of a boy, who lived five weeks after the accident had happened; and Latour records the case of a soldier, who lived for six years after being wounded with a musket-ball in the side, and in the right ventricle of whose heart the bullet was found lodged, lying against the septum. From the inquiries of Olivier it would appear that the right ventricle is more frequently wounded than the left; next, the apex or base of the heart, then, the right auricle, and least frequently, the left auricle. The signs of an injury of the heart that is not immediately fatal, are not very positive. The hemorrhage, the direction of the wound, the dyspnoea, the ex- treme anxiety, syncope, and irregularity with smallness of the pulse, indicate the probable nature of the mischief. The most important information, however, is to be derived from auscultation; the occurrence of friction, or some other abnormal sound, with absence of impulses, and increased dulness on percussion over the region of the heart, may point to the seat of the injury. The pericardium may be injured without the heart being wounded; by stabs, by gun-shot violence, or severe contusions of the chest. In injuries such as these, inflammation is set up, and the ordinary auscultatory signs of pericarditis, such as friction or creaking sounds, with dulness on percussion, are distinctly perceptible. When blood is effused into the pericardial sac, these morbid sounds may be absent, but the heart's impulse is weak, and the circulatory sounds dis- tant, the layer of blood preventing, as Mr. Guthrie has pointed out, the contact of the cardial and pericardial surfaces. Ruptures of the heart from external violence, without penetrating wound of the chest, are not of frequent occurrence. Mr. Gamgee has, however, collected 27 published cases of this accident. On analyzing these he finds that, in at least one half of the cases the pericardium was intact; 12 of the ruptures were on the right, 10 on the left side. The right ventricle was ruptured in 8, and the left in 3 cases; whereas the left auricle was torn in 7, and the right in only 4 instances. Death is usually nearly instantaneous, though there are instances on record in which the patient has made some exertion after the rupture had taken place, and has even lived for several hours. In a case of rupture of the right auricle recorded by Rust, the patient survived fourteen hours. The only case that has occurred in my practice was that of a man brought into the hospital dead, having fallen from the top of a cart. The right shoulder was bruised and the clavicle broken — showing clearly that he had pitched on that side; there was no other bruise about the body, or evidence that the wheels had passed over him. On examination, the liver was found extensively torn, in fact smashed, and the pericardium was distended with blood—there being a triangular ragged aperture at the anterior part of the auricular appendage of the left auricle, through which it had escaped. Wounds of the aorta and vena-cava are as fatal as those of the heart itself. Dr. Heil has, however, recorded a case in which a patient recovered, and lived for a twelvemonth, after receiving a stab that penetrated the ascending aorta. INJURIES OF THE ABDOMEN AND PELVIS. 325 CHAPTER XXI. INJURIES OF THE ABDOMEN AND PELVIS. Injuries of the abdomen are of frequent occurrence. They may be divided into contusions of the abdomen, with or without rupture of internal organs; into non-penetrating wounds, and into penetrating toounds; either uncompli- cated, or conjoined with injury or protrusion of some of the organs contained in this cavity. Contusions of the abdominal walls from blows or kicks, usually terminate without serious inconvenience, but in some cases are followed by peritonitis of a very acute character, which may prove fatal. In other cases again, the abdominal muscles may be ruptured, although the skin may remain unbroken. A man was admitted under my care into the hos- pital, who had received a blow from the buffer of a railway carriage upon his abdomen, he complained of great pain at one spot, and on examination after death, we found the rectus muscle torn across without injury either to the in- teguments or the peritoneum. If the patient live, an injury of this kind is apt to be followed by atrophy of the muscular substance, and perhaps by the occur- rence of a ventral hernia at a later period. Occasionally the contusion is followed by abscess in the abdominal wall, which has a tendency to extend widely between the muscular planes. These abscesses should be opened early, lest they burst into the peritoneal cavity and occasion fatal inflammation. A contusion of the abdomen is often associated with rupture of some of the viscera. In military practice these internal injuries are met with in the so-called "wind-contusions;" in civil practice they commonly result from blows, kicks, the passage of a cart-wheel over the abdomen, or the squeeze of the body be- tween the buffers of two railway carriages. These " Buffer-accidents" are now of common occurrence in hospital practice, resulting usually from the careless- ness of railway guards and porters, who, trying to pass between carriages in motion, are caught and squeezed between the buffers. In these cases the most fearful internal injuries occur, often without an external wound. A man was admitted under my care into University College Hospital, in whom the liver, stomach, spleen, and kidneys, were crushed and torn; the heart was bruised, being ecchymosed on its surface, and one of the lungs lacerated, without there being any rupture or bruise of the skin, or fracture of the ribs. In this way any of the abdominal organs may be torn or contused, the particular one injured depending on the situation of the blow. The organ that is most frequently crushed in this way is the liver, owing to its large size and the ready lacerability of its structure; the other solid organs, such as the spleen and kidneys, not suffering so frequently: the pancreas I have never seen injured. Amongst the hollow organs the stomach most commonly suffers, and it is especially likely to do so if distended by a meal at the time that it is struck. Any portion of *he intestinal canal may be lacerated. I have seen the duodenum, the ileum, the jejunum, and the large intestine ruptured in different cases: the mesentery likewise may be torn and the spermatic cord snapped across. The sufferer usually dies in the course of a few hours, or at the utmost at the end of two or three days after the receipt of these injuries, from hemorrhage into the abdominal cavity, conjoined with shock to the system. It is seldom that life is prolonged sufficiently for peritonitis to be set up, though this is the chief danger to be apprehended in those cases that survive the more immediate effects of the accident. When the solid organs are ruptured, death most com- monly ensues from hemorrhage. The shock in itself may prove fatal, though 326 INJURIES OF THE ABDOMEN AND PELVIS. there be but little internal mischief done; thus, I have seen a man die collapsed eight hours after a buffer accident, in whom no injury was found except a small rupture of the mesentery, attended with but very slight extravasation of blood. It does not follow, however, that these injuries are necessarily fatal. Patients have lived after all the signs of rupture of the liver or the kidneys, passing bloody urine, and having circumscribed peritonitis, and when death has occurred, at a later period cicatrices have been detected in these organs; this indeed is nothing more than has been met with in ordinary penetrating wounds of the abdomen. A patient was admitted into the University College Hospital for a severe blow upon the back, accompanied by symptoms of renal injury; on his death from other causes, nine weeks after the accident, an extravasation of blood, with the marks of recent cicatrisation, was found in the left kidney. Rupture of the liver is by no means invariably speedily fatal. It may be so from great extravasation of blood, but when this is not largely poured out the patient may live for some considerable time. A man was admitted last year under my care into University College Hospital, who had been crushed between the buffers of two railway carriages. He was collapsed, and appa- rently moribund, but rallied in a few hours. Two days after the accident, great pain and tenderness in the right hypochondrium were complained of, and dulness on percussion was found to extend as low as the umbilicus. He became jaundiced, and there were symptoms of low peritonitis; these were fol- lowed by great swelling of the abdomen, which became tympanitic; the perito- nitis continued, and symptoms of intestinal obstruction came on, the dulness increasing, with fluctuation in the flanks. He died on the sixteenth day after the accident, and, on examination, no less than 240 oz. of bilious fluid, mixed with flakes of lymph, were found in the abdominal cavity; the obstruction being dependent on the pressure of this effusion, and on the matting together of the intestines by lymph. There was a large rent found in the thick border of the liver, which was beginning to cicatrise. The symptoms of an internal abdominal injury are often extremely equivocal. If the liver or spleen have been lacerated, there will be all the effects of severe shock to the system, accompanied by those of internal hemorrhage; coldness, and pallor of the surface, a small and feeble pulse, anxiety of countenance, and great depression of the vital powers, with pain at the seat of injury, and perhaps dulness on percussion, from extravasated blood; symptoms that speedily terminate in the death of the patient. If the kidneys are injured, the patient will commonly experience a frequent desire to pass water, and this will be tinged with blood, often to a considerable extent. The absence of blood in the urine must not, however, be taken as an indication that the kidney is not injured; it may be so disorganized as to be totally incapable of secreting, and consequently no bloody urine finds its way into the bladder. A man was admitted into the hospital under my care for a buffer-injury of the back; he passed water untinged with blood, but after death his right kidney was found completely smashed by the blow, with an extensive extravasation of blood in the cellulo-adipose tissue around it; here it was evident that the disorganization was so sudden and complete, that no bloody urine had found its way into the bladder. When the stomach is ruptured, it commonly happens that the nature of the accident is revealed by bloody vomiting; and when the intestines have been torn, by the admixture of blood with the stools, if the patient lives long enough to pass any. These signs, however, do not occur in all cases. A man was ad- mitted into the hospital under my care, whose abdomen had been squeezed be- tween a cart-wheel and a lamp-post; during the five hours that he lived after the accident, he vomited several times, bringing up a meal that he had taken immediately before. In the vomited matters there was no blood to be seen, but TREATMENT OF ABDOMINAL INJURIES. 327 on examination after death it was found that the liver and spleen were not only ruptured, but the stomach torn almost completely across near the pylorus. Emphysema of the abdominal wall, and subsequently of the trunk generally, may result from the escape of flatus from a wounded intestine into the sub- peritoneal cellular tissue, and thence into the more superficial cellular planes. When this takes place, the same doughy, puffy, inelastic, crepitating swelling of the subcutaneous cellular tissue, that is met with in the thoracic form of the affection is observed. The emphysema usually commences in one or other flank, and may then creep on up towards the axilla, or in front of the abdomi- nal wall. As a diagnostic sign, this form of emphysema is valuable in those cases in which the intestines have been injured, either without any wound of the ab- dominal parietes, or if there be wound, without protrusion of the injured por- tion of gut. In two cases in which I have observed it, this condition was the only positive sign of intestinal injury. In one case, the transverse duodenum had been ruptured where uncovered by peritoneum, by a buffer-accident; and in the other, the rectum and meso-rectum had been traversed by a pistol-ball. In both these cases the emphysema was extensive, the flatus having directly passed into the subperitoneal cellular tissue. In other cases it may do so more indirectly by having, in the first instance, passed into the cavity of the abdomen, and rendered that tympanitic; and so, as in thoracic emphysema from pneumothorax, escaped from this into the cellular tissue at the edges of the wound. The diagnosis of abdominal emphysema requires to be made from thoracic emphysema, and from putrefactive infiltration of air in the cellular tissue. In the first case it may readily be effected by observing an absence of the signs of thoracic injury, and by the situation of the emphysema in the posterior or lateral abdominal wall, or around the lips of a wound. From putrefactive emphysema the cause, and the absence of low inflammation of the cellular tissue, renders the diagnosis easy. The treatment of the various injuries of the abdomen that have just been described is of a very simple character. If the symptoms indicate laceration of one of the viscera, little can be done during the state of collapse supervening on the accident, beyond keeping the patient quiet, and employing the means that have been recommended for lessening the effects of shock upon the system. If the patient survive this period, we must guard against the supervention of peritonitis, and limit, if possible, the extravasation of blood into the abdomen, should there be indications of its occurrence, by the employment of treatment that will presently be described. Wounds of the abdominal wall that do not penetrate the peritoneal cavity, if uncomplicated with internal injury, usually do well, and require to be treated on ordinary principles. If incised, and so extensive as to require sutures, the stitches should only be introduced through the skin, never through muscular or tendinous structures, the union of which could not be effected in this way; the parts injured must also be relaxed by careful attention to position. Wounds that penetrate the cavity of the abdomen are of especial interest, on account of the frequency with which they are complicated with peritonitis, and with injury of some of the viscera. They may, for practical purposes, be divided into those that penetrate the peritoneal sac, without wounding or causing the protrusion of any of the contained organs, and those that are complicated with protrusion, or wound of some of the viscera. 1st. Penetrating wounds of the abdomen without visceral protrusion or injury, are somewhat difficult to distinguish from simple wounds of the abdominal wall, though the escape of a small quantity of reddish serum may reveal the nature of the accident. In these cases the surgeon should be careful not to push his examination too far, by probing, or otherwise exploring the injury. In the ab- 328 INJURIES OF THE ABDOMEN. Bence of peritonitis or other signs of mischief, he must treat it as a simple wound of the abdominal wall, and should any complication occur, must meet that in the way that will immediately be described. 2d. In a penetrating wound with protrusion or injury of the viscera, the risk is necessarily greatly increased; here the chief danger is from peritonitis, in- duced either by the wound, — by the extravasation of the intestinal contents into the peritoneal cavity, or by the accumulation of blood in it. It but seldom happens that death results from hemorrhage in these cases, though this may, of course, occur if any of the larger vessels be injured. 3d. Protrusion of uninjured intestine, mesentery, or omentum, may take place through the wound in the abdominal wall. This protruded mass is always of very large size in comparison with the aperture from which it escapes, the sides of which being overlaid by it, constrict it pretty tightly, so as to form a distinct neck to the protrusion. If left unreduced, the mass speedily loses its polish and bright color, becoming dull and livid from congestion ; it then inflames, and soon becomes gangrenous from the pressure exercised upon it by the sides of the aperture through which it has passed. 4th. In many cases the protruded intestine is wounded. The existence of this further injury will readily be ascertained, by the escape of flatus, or of the more fluid contents of the gut. The characters of the wound vary, as Travers has pointed out, according to its size. If it be a mere puncture in the gut, or even an incision two or three lines in length, an eversion or prolapsus of the mucous membrane will take place, so as to close it to an extent sufficient to pre- vent the escape of its contents. If the aperture be above four lines in length, this plugging of it by everted mucous membrane cannot take place, and then the contents of the bowel are more freely discharged; but, even under these circumstances, there will be a tendency to the protrusion of the membrane, which forms a kind of lip over the edge of the cut. 5th. A wounded intestine which does not protrude, but remains within the peritoneal sac, presents the same conditions. In these cases, however, there is the additional danger of the extravasation of the intestinal contents into the peri- toneal cavity.' This extravasation of feculent matter, unquestionably one of the greatest dangers that can occur in wounds of the abdomen, inasmuch as by its irritating qualities it gives rise to and keeps up the most intense peritonitis, takes place less frequently than might be expected. For this there are several reasons. In the first place, we have already seen, that, if the wound in the gut be below a certain size, there is a natural tendency to its occlusion by eversion of the mucous membrane into it. Besides this, it must be borne in mind that, though in ordinary language we speak of the "cavity" of the abdomen, there is in reality no such thing; there being no empty space within the perito- neal sac into which extravasated matters could fall, but the whole of the visceral contents of the abdomen being so closely and equably brought into contact by the pressure of the abdominal muscles and of the diaphragm, that it requires some degree of force for the intestinal contents to overcome this uniform sup- port, and to insinuate themselves between the coils of contiguous portions of intestine. The influence exercised by the continuous pressure of the abdominal walls upon the intestinal contents, is well shown by the greater facility with which these escape from a portion of wounded intestine that has been protruded, than from one that is still lying within the abdomen. In the former case, faeces will escape from a much smaller aperture than in the latter instance, in conse- quence of the gut not being supported on all sides by the uniform pressure to which it is subjected within the abdomen. It is seldom, indeed, that faeces are extravasated from gut that is not protruding, unless it be very full at the time of the injury, or the wound in it be very extensive. The influence of the equable pressure of faeces was well illustrated in a case in University College Hospital, of a man who was shot through the abdomen. The intestines, which WOUNDS OF THE INTESTINES. 329 contained much feculent matter, were traversed by the bullet in four places. He lived twenty-four hours, and yet no feculent extravasation took place. Blood is extravasated, more readily than the intestinal contents in wounds of the abdomen. This is in a great measure owing to the vis-a-tergo influence exist- ing in an artery of moderate size, such as one of the branches of the mesenteric, being sufficient to overcome the equable pressure and support of the abdominal walls. These extravasations, whether of faeces or of blood, when once formed have little tendency to diffuse themselves, but become localized in the neighborhood of that part from which they were originally poured out, owing, in the first instance, to the surrounding pressure, and, at a later period, to the deposit of plastic matter between the folds of intestine and neighboring viscera. In this way the diffusion of irritating matters through the abdominal cavity being pre- vented, the likelihood of the occurrence of wide-spread and fatal inflammation is much diminished. The existence of these extravasations may, in many cases, be recognized by dulness on percussion around the wound, by the localized swelling to which they give rise, and, sometimes by their escape through the external aperture. In the treatment of penetrating wounds of the abdomen, we must first consider the management of the injured parts; and, afterwards, the prevention or cure of the consecutive peritonitis. If the wound have not implicated any of the abdominal viscera, it must be closed by relaxing the abdominal muscles by position, by introducing a few points of suture through the integuments, if it be extensive, and by applying a compress and plaster, supported by a bandage. The patient should then have a full dose of opium given him; about 2 grains of solid opium or 40 minims of the liquor sedativus, which must be repeated in from four to six hours, so that the effects may be kept up. He should then be kept perfectly quiet in bed, and no nourishment given for a few days, except barley-water and ice. The bowels should not be opened by aperient medicine, lest abdominal irritation be set up, but oleaginous enemata may be administered at the end of a week or > ten days. ^v. If the intestine be wounded but not protruding, we must endeavor to limit the peritonitis that will ensue, and also to prevent feculent extravasation. With this view the patient should be laid on the injured side with the wound depend- ent, so as to allow the faeces to escape through it if disposed to do so. If the injury be about the umbilicus he must lie upon his back with the knees drawn up and bent over a pillow. Opium must then be administered in the full doses already indicated, and repeated in grain doses at least every fourth or sixth hour, so that the system be kept well under its influence. The value of opium in these cases is very great; it not only seems to moderate the inflammation that takes place in the peritoneum, but is of the greatest utility in preventing ex- travasation of faeces. This it does by arresting the peristaltic movements of the intestine, and thus, by keeping it from change of position, lessening the chance of the escape of its contents. This arrest of the intestinal movements also tends greatly to the closure of the wound. Travers has shown experimentally, and his investigations have been confirmed by subsequent observations on the human subject, that wounds of the intestines are closed by lymph that is thrown out, not only from the contiguous peritoneal surfaces of the part actually injured, but from that of neighboring coils; so that the aperture in the gut becomes perma- nently glued and attached to the structures in its vicinity. In order that this process should take place, it is necessarily of the first importance that the move- ments of the bowel be paralyzed; and it is a beautiful provision of nature that the very inflammation which closes the wound, arrests that peristaltic action, the continuance of which would interfere with its agglutination to, and closure 330 INJURIES OF THE ABDOMEN. by, the neighboring parts. Until the necessary degree of inflammation to effect this is set up, the intestinal movements must therefore be arrested by opium. If extravasation of feculent matter have taken place into the cavity of the abdomen, an attempt might be made to facilitate its escape by removing the stitches and plasters from the external wound, and placing the patient on the injured side, so that this may be in the most dependent position; should the lips of the wound have already become adherent to one another, they might even be gently and carefully separated by the introduction of a probe, and in this way an outlet afforded the effused matters. When a portion of intestine or of omentum has protruded, it should be replaced as speedily as possible, before strangulation has occured to occasion gangrene of the protruded mass. In order to effect reduction, the abdominal muscles should be relaxed by bending the thigh upon the abdomen, when the surgeon may gradually push back the protrusion by steady pressure upon it; no force must, however, be had recourse to, or any rough handling of the exposed and delicate parts; but if it be found that their return cannot readily be effected, owing to the constriction of the neck of the tumor, the aperture through which they have escaped must be carefully enlarged, in a direction upwards, by means of a probe-pointed bistoury, or a hernia-knife, guided by a flat director. The incision necessary to enlarge the opening sufficiently to admit of reduction, need not exceed half-an-inch in length. In replacing the protruded parts, whether by the aid of incision, or not, care must be taken that they are fairly put back into the cavity of the abdomen, and not pushed up into the sheath of the rectus, or into the subserous cellular tissue lying before the peritoneum; an accident that would be fatal by allowing the constriction of the neck of the protrusion to continue unrelieved. In effecting the return the surgeon should not push his finger into the cavity of the abdomen, but must content himself with simply replacing the protruded gut, or omentum, and allowing it to remain in the immediate neighborhood of the wound in the abdominal wall, to which it will contract adhesions; and through which its contents may escape, in the event of any sloughing action being set up in it. If the protrusion be inflamed, it must equally be replaced without delay; but should the intestine have become gangrenous from continued constriction and exposure, no attempt at reduction should be made, but an incision must be carried through it, so as to allow of the escape of faeces, and the formation of an artificial anus. If the protruded omentum be gangrenous, it must be excised on a level with the peritoneum, to the aperture in which that portion lying within the abdomen will have contracted adhesions. If the intestine that protrudes be wounded, the treatment of the aperture in the gut will call for special attention; and surgeons have been somewhat divided as to the line of practice that should be pursued in such a case. The question that has been left open is, as to the propriety of stitching up the wound of the intestine. Scarpa and S. Cooper were opposed to this practice on the ground that it does not prevent extravasation, and that the stitches produce irritation by acting as foreign bodies. They proposed to return the wounded gut, taking care, however, to leave the aperture in it to correspond with that in the abdo- minal wall, so that an artificial anus might be established by the cohesion of the edges of either opening to one another, these adhesions preventing extrava- sation. To this practice the great objection exists that extravasation will probably occur before there has been time for the effusion of lymph, and the agglutination of the contiguous surfaces; besides which, it is impossible to secure the necessary correspondence between the two apertures, the wounded gut being very liable to alter its position after it has been replaced. It has also been found by experience that one of the objections urged against the employ- ment of a suture, that it cannot prevent the escape of feculent matter, is not valid. If it be properly applied, it may effectually do so, as was shown by a TREATMENT OF WOUNDS OF THE ABDOMEN. 331 successful case under my care, the details of which have been published in the "Lancet," for 1851. That the stitches act as sources of irritation to any serious extent is also doubtful. Travers found by experiment that when a wounded gut was sewn up, and returned into the abdomen, the sutures quickly became bridged or coated over with a thick layer of lymph, and gradually ulcerating their way inwards, at last dropped into the cavity of the intestine, being dis- charged per anum, and leaving a firm cicatrix at the point to which they had been applied. For these various reasons, Guthrie, Travers, and other surgeons of experience, advocate the practice of stitching up a wounded and protruding intestine, with which opinion I entirely agree. Much, however, depends upon the way in which the sutures are applied. They should be introduced by means of a fine round needle, armed with sewing silk, in such a way that the perito- Fio. 133. neal surfaces on either side of the wound alone are brought into contact as adhesion takes place solely between them, the wound in the other structures of the gut filling up by plastic deposit. It has been recommended that the needle should only penetrate the peritoneal and cellular coats, no muscular tissue being taken up in it, lest retraction of the included fibres, by dragging upon the stitches, might re-open the wound. This, however, it is extremely difficult to do. The safer plan is doubtless to carry the suture through the whole thickness of the gut, bringing the stitches out at about the one-sixth of an inch from the edge of the cut, from each other, in such a way that the serous surfaces are drawn into apposition (fig. 133). The kind of suture that should be used is the " glover's stitch." When the lips of the wound have been nearly brought into apposition in this way, it has been proposed to leave the end of the thread hanging out of the aperture of the abdominal wall, and to withdraw it when it becomes loose; but I think it better not to leave it, as it might induce great irritation, acting like a seton in the peritoneal cavity. It is better, therefore, to cut the ends short close to the knot, when the suture will eventually become covered with lymph, and find its way into the inside of the gut by ulcerating through the muscular and mucous coats. After the aperture in it has been thus closed, the protruded portion of the intestine must be reduced, having previously been properly cleansed with a little lukewarm water. The reduction must be effected in the way that has already been described, the surgeon being especially careful not to push the wounded coil of intestine far into the abdomen, but to leave it close to the external orifice, so that in the event of extravasation occurring, or the stitches giving way, a ready outlet may be afforded. Should the wound in the abdo- minal wall be extensive, it must be closed by means of sutures and plasters, supported by a bandage, the inferior angle being left open to allow of the escape of extravasation. The wound in the peritoneum had better be left; but should it be very extensive, the practice that was successfully adopted under such circumstances by Mr. Wood, of stitching up the aperture in it, might be had recourse to. The after-treatment must be conducted in all respects on the same principles that guide us in the management of an intestine that has been wounded without protruding. Care must be taken, by attention to the position of the patient, and by the free administration of opium, to keep the bowel as quiet as possible near the external opening; the urine should be drawn off twice in the twenty-four hours, and no purgative whatever administered, lest by 332 INJURIES OF THE PELVIC VISCERA. the excitation of peristaltic action, adhesion be disturbed and extravasation take place. After the lapse of six or eight days, an enema may be thrown up, and repeated from time to time. No food should be allowed for the three first days, during which time tea and barley-water should be freely taken; after this, beef- tea and light food that leaves no residue may be administered. Traumatic peritonitis is the great danger to be apprehended in all these injuries of the abdomen, and it is by inducing this that extravasation of faeces or of blood so frequently proves fatal. It is true that a certain degree of inflammation of the peritoneum is necessary for the healing of all abdominal wounds, but it must be limited in extent and plastic in character. It is the more diffuse form of peritonitis, attended by the exudation of turbid serum, and shreddy, ill-conditioned lymph, that is so speedily fatal. In these cases, we meet with the ordinary symptoms of the idiopathic form of this affection; — uniform tenderness about the abdomen, with much tympanitis, more par- ticularly in the neighborhood of the injury, with occasional stabbing pains, followed by tympanitic distension, vomiting, and hiccup, a small, quick, hard pulse, often assuming a wiry incompressible character, with considerable pyrexia, and great anxiety of countenance. The traumatic peritonitis will set in and run its course with great rapidity; in a case in University College Hospital, already alluded to, of bullet wound of the abdomen, the patient lived 24 hours. Two or three pints of serous effusion with much puro-plastic matter, and great reddening of the whole of the visceral and much of the parietal peritoneum had ensued. As the inflammatory extravasation increases, dulness on percussion will manifest itself—usually first on the flanks, and then gradually extending forward until it may occupy a great extent of surface in the abdomen. In the treatment of this disease we must be guided by the character of the inflamma- tion. If it be of a sthenic form, and the patient young and robust, he should be bled freely in the arm, and have leeches abundantly applied over the surface of the abdomen; a pill composed of two grains of calomel and one grain of opium may then be administered every sixth hour, or oftener, if the patient be not influenced by the narcotic; and rigid abstinence from all except ice and barley-water should be enforced. If the peritonitis be the result of a wounded intestine, it is safer to omit the calomel, using mercurials instead to the inside of the thighs, but giving opium freely. When the peritonitis occurs in an old or feeble subject, our principal trust must be in the administration of opium and free leeching of the abdomen, followed perhaps by a blister, which may be dressed with mercurial ointment. In these cases, however, early support will be required, with perhaps the administration of wine or stimulants. The inflammatory extravasation will gradually be absorbed under the influence of the calomel, aided by blisters. INJURIES OF THE PELVIC VISCERA. Rupture of the bladder, from blows upon the abdomen, or penetration of it by bullet wounds, is not of very unfrequent occurrence, and is especially liable to happen if this organ be distended at the time it is struck, when very slight degrees of accidental violence, as running against a post, falling off a bed, may occasion its rupture. The effects of these injuries vary considerably, according to the part that has given way or been wounded. If the laceration have oc- curred in those portions of the viscera that are invested by peritoneum, the urine will at once escape into the pelvic and abdominal cavities, and speedily occasion death by the intense irritation and inflammation set up by it. I have, however, seen a case in which, even under these circumstances, the patient survived ten days. If, on the other hand, that portion of the organ have been ruptured which is uncovered by peritoneum, the urine will infiltrate into the cellular tissue between this membrane and the abdominal wall, and diffusing INJURIES OF THE URETHRA AND PERINEUM. 333 itself widely, produce destructive sloughing of the tissues amongst which it spreads. In these cases life may be prolonged for some days, when the patient commonly sinks from the combined irritative and inflammatory action. Still, however, it must be borne in mind, that numerous cases of injury of the bladder, more especially from gun-shot wounds, have recovered, and that, although we must look upon this accident as of the gravest character, yet that it cannot be considered as being necessarily fatal. The symptoms of a ruptured bladder are sufficiently evident; the injury in the hypogastric region, followed by collapse, by intense burning pain in the abdomen and pelvis, with inability to pass the urine, or, if any have escaped from the urethra, its being tinged with blood, are usually sufficient to point to the nature of the accident. If in addition, it is found, on introducing a catheter, that the bladder is empty, or that but a small quantity of bloody urine escapes, the surgeon may be sure that this organ has been burst. In the case of gun-shot injury, the escape of urine, which generally takes place through the track of the bullet, will afford incontestable evidence of the mischief that has been produced. In the treatment of these cases, the most important indication is the preven- tion of further extravasation by the introduction of a full-sized elastic catheter into the bladder, which must be left there, so that the' urine may dribble away through it as fast as it accumulates. If any sign of extravasation makes its appearance, free and deep incisions should be made into the part, so as to facili- tate the early escape of the effused fluid and the putrid sloughs. I cannot but consider all active antiphlogistic treatment as out of place in these injuries, never having seen the slightest benefit from their employment. The only chance that the patient has, if once extensive extravasation have occurred, is that there may be sufficient power left in the constitution to throw out a barrier of lymph that will limit the diffuse and sloughing inflammatory action set up, and the prospect of this would certainly not be increased by the employment of depletory measures. There will also be so great a call upon the powers of the system at a later period, after sloughing has fairly set in, that a supporting or even stimulating plan of treatment would rather be required. Foreign bodies, such as pieces of catheters, tobacco-pipes, pencils, &c, are occasionally met with in the urinary organs, having been introduced through the urethra. In some cases they are soon spontaneously expelled, but more usually they require extraction; sometimes they may be fortunately seized with a small lithotrite or urethral forceps in the direction of their long axis, and thus extracted; but more frequently they require to be removed through an incision made into the bladder. This is more safely done by the mesial, rather than by the lateral operation of lithotomy. It occasionally happens that musket-balls, pieces of clothing, &c, have been lodged in the bladder in gun-shot wounds of that organ. These speedily become incrusted with urinary deposits, and giving rise to the symptoms of stone in the bladder, require to be removed by lithotomy, an operation that has proved very successful in these cases, evidently in consequence of the healthy condition of the urinary organs. Mr. Dixon has collected from various works the details of 15 cases, in which balls that had either primarily entered the bladder or found their way into this organ by abscess or ulceration after being lodged in the neighborhood, had been extracted by operation. In 10 of these cases the result was successful; in the remaining 5 no record is made of the termination. Mr. Stanley has related a remarkable case in which the ureter was ruptured by external violence, and in which the patient recovered; a very large accumu- lation of fluid forming on the injured side of the abdomen, with considerable circumscribed tumefaction and fluctuation, and which required repeated tapping, In another case in which the pelvis of the kidney was ruptured, a similar col- 334 INJURIES OF THE PELVIC VISCERA. lection of urine took place within the abdomen, requiring tapping; as much as six pints being removed at one sitting. On examination after death, which occurred on the tenth week from the accident, a large cyst was found behind the peritoneum, communicating with the pelvis of the kidney. Laceration of the urethra not uncommonly happens from kicks on the peri- neum, or in consequence of falls from a height, the patient coming astride upon a girder or a plank of wood, and rupturing the urethra at the triangular liga- ment. In these cases there is great bruising, and sometimes wound of the perineum, and if an attempt have been made to pass water, the patient will find himself unable to do so, the effort being also accompanied by deep and burning pain, followed perhaps by the discharge of blood or a few drops of bloody urine from the urethra. The consequences of this injury are often most disastrous. The immediate result is usually extravasation of urine into the perineum, which, if not checked by proper treatment, rapidly passes forward through the scrotum up upon the abdomen, giving rise to extensive sloughing of every portion of cellular tissue with which it comes in contact, and leading perhaps to the rapid destruction of the integuments of these parts, and the consequent formation of extensive and deep abscess and ulceration. If the patient recover from this mischief, he will very likely do so with a fistulous opening in the perineum, and ultimately suffer from a very intractable form of stricture, which in some cases may be completely impassable, in consequence of a portion of the urethra having been torn across and sloughing away. The treatment of this injury consists in the early introduction of a catheter into the bladder. If this can be done before the patient has made an attempt at passing his urine, much of the immediate danger of the case may be averted, by the prevention of urinary infiltration. The catheter, which should be an elastic one, must be left in the bladder for a few days. If any hardness, throbbing, or other sign of irritation occur in the perineum, free incision should be made into the part, so as to afford a ready outlet for any urine that may have been effused. If the surgeon find it impossible to get a catheter into the blad- der, the urethra being torn completely across, he should pass it as far as it will go, and then putting the patient in the position for lithotomy, make a free inci- sion in the mesial line, upon the point of the instrument, so as to make an opening in the perineum communicating with the deeper portion of the urethra, or he might puncture through the rectum if the bladder be distended; but it is best to get a free outlet for the urine through the perineum, if possible. As the urine becomes extravasated, the surgeon must follow its course with free and deep incisions, supporting the strength of the patient at the same time by a due allowance of stimulus and nourishment. If, when the urethra is com- pletely torn across, the urine finds a difficulty in escaping, and relief is not afforded by the perineal incision, the bladder becoming distended, it should be tapped through the rectum, in the way that will be described when we come to Bpeak of diseases of the urinary organs. Foreign, bodies are occasionally impacted in the vagina or rectum. A variety of things, such as pieces of stick, glass bottles, gallipots, &c, have been intro- duced into these canals. Their extraction is often attended with great difficulty, in consequence of the swelling of the mucous membrane over and around them, and the depth to which they have been pushed. In order to remove them, lithotomy or necrosis forceps may be required. In some cases, the foreign body has been found to transfix the wall of the canal in which it is lodged, and by penetrating the peritoneum, has speedily occasioned the patient's death. A remarkable case of this kind has recently occurred in my practice, in which a cedar pencil, five inches long, and cut to a point, had been forced up through the posterior wall of the vagina of a young woman into the abdominal cavity. Here it transfixed two coils' of the small intestine, and after a sojourn of eight months was extracted by an incision through the anterior abdominal wall, mid- BURNS AND SCALDS. 335 way between the umbilicus and Poupart's ligament, where its point was engaged in the fascia transversalis. It had occasioned repeated attacks of peritonitis, and after its extraction death resulted from that cause. Laceration of the Perineum.—The perineum is occasionally ruptured during parturition. When the laceration is of limited extent and recent, union may usually be effected by bringing and keeping the thighs together immedi- ately after its occurrence. Should the lacerations have existed for some weeks, but not extend into the sphincter ani, it may usually readily be repaired by paring the edges freely, and passing two deep quilled sutures so as to bring the opposite sides together. When the laceration is very extensive, extending through the posterior wall of the vagina, the perineum, the sphincter ani, and the rectum, in fact tearing through the recto-vaginal septum, more energetic and careful treatment will be required. The bowels having been well cleared out, and the patient being placed in the position for lithotomy, the edges and sides of the rent must be freely and deeply pared. The sphincter ani should then be freely divided on either side of the coccyx, as recommended Fig. 134. by Mr. Brown, in order that its action may be paralyzed and all tension of the parts removed. Three points of quilled suture should then be deeply passed through the freshened sides of the laceration, and the edges brought together by a few points of interrupted suture (fig. 134). The success of the operation will entirely depend on the attention bestowed on the after treatment of the case; the mode of conducting this has been laid down with much precision by Mr. Brown. The principal points to be attended to are as follows: — Im- mediately after the operation, a full dose of opium should be given, and a grain administered every sixth hour with the view of arresting all intestinal action. The patient should be laid on her side, and a catheter retained so as to prevent any dribbling of urine over the raw edges, which would be fatal to their union. The deep sutures should be left in for four or five days, the superficial ones for about a week; during this period 1 have found it advantageous to keep the part covered with collodion. When the sutures are removed, a pad of dry lint, supported by a T bandage, should be applied. The bowels should not be allowed to act for at least ten or twelve days, lest the freshly united surfaces be torn through. During the whole of this period the patient's strength must be supported by good diet, and scrupu- lous attention paid to the cleanliness of the parts. Plastic operations of this kind should not be performed unless the patient is in a good state of health. CHAPTER XXII. effects of heat and cold. BURNS AND SCALDS. A burn is the result of the application of so great a degree of heat to the body as to produce 'either inflammation of the part to which it is applied, or charring and complete disorganization of its tissue. A scald is occasioned by the application of some hot fluid to the body, giving rise to the same destruc- tive effects that are met with in burns, though differing from them in the appearances produced. 336 BURNS AND SCALDS. Local effects.—Burns and scalds vary greatly in the degree of disorganization of tissue to which they give rise; this variation depending partly upon the intensity of the heat that is applied, and partly upon its duration. The sudden and brief application of flame to the surface produces but very slight disor- ganization of the cuticle, with some inflammation of the skin. If the part be exposed for a longer time to the action of the flame, as when a woman's clothes take fire, the cutis itself may be disorganized, and, if the heat be still more intense, as when molten metal falls upon the body, the soft parts may be deeply charred, or the whole thickness of a limb destroyed. So, also, the effects of scalds vary greatly, not only according to the temperature of the liquid, but according to its character; the more oleaginous and thicker the fluid, the more severe usually will the scald be. These various results of the application of heat to the surface have been arranged by Dupuytren into six different degrees of burn. In the 1st, there is merely a scorch of the skin, slight redness with efflorescence of the cuticle, but no permanent injury. In the 2d degree there is not only general redness of the part to which the heat has been applied, but vesicles form, either at once or in the course of a few hours, and sometimes attain a very considerable mag- nitude. In the 3d degree, the cutis itself is destroyed, yellowish-grey or brownish eschars forming, which involve the whole thickness of the skin, the surrounding integument being more or less reddened and vesicated, and the part extremely painful. If this amount of injury is the result of a scald, the eschars will be found to be soft, pulpy, and of an ashy-grey character. In the 4th decree, the whole thickness of the skin and part of the subcutaneous cel- lular tissue are destroyed, dry, yellowish-black, insensible eschars being formed, with considerable inflammation around them, leaving, on their separation, deep and luxuriantly granulating ulcerated surfaces. In the 5th degree, the eschars extend more deeply, implicating the muscles, fasciae, and soft structures. And, in the 6th degree, the whole thickness of the limb is completely destroyed and charred. This is the celebrated classification introduced by Dupuytren, and adopted by most writers on the subject, as a practical exposition of the local effects of burns. These various degrees are usually found associated, to a greater or less extent; indeed, in the more severe forms, the three or four first degrees are almost invariably met with. The primary local effect, then, of a burn, if superficial, is to excite inflam- mation of the skin; if more extensive, to destroy the vitality of more or less of the soft structures, and even the bones. When the cuticle is unbroken, the inflammation speedily subsides, with some desquamation. When the soft parts are charred, they are detached by a process of ulceration, analogous to what happens in the separation of sloughs, and an ulcerated and suppurating surface is left, remarkable for the large size, the florid color, the great vascularity, and the rapid growth of its granulations. The cicatrization of such an ulcer as this, though generally proceeding with great rapidity, has a constant tendency to be arrested by the exuberance of the granulations. The cicatrix that results is usually thin, and of a bluish-red color, and is especially characterized by a great disposition to contract, becoming, after a time, puckered up, and much indu- rated. This process of contraction and hardening, which begins immediately on the completion of cicatrization, continues for many months, giving rise fre- quently to the most serious deformities, and to the complete loss of motion and use in parts. These cicatrices are of a fibro-plastic and fatty character, and often extend deeply between, and mat together the muscles, vessels, and soft structures of a limb, of the face, or neck. The constitutional effects resulting from burn are of the most serious and important character; they are dependent not so much upon the depth of the injury as upon its situation, the extent of surface implicated, and the age of the patient. Thus, a person may have his foot completely charred and burnt off by STAGES OF BURNS. 337 a stream of melted iron running over it, with far less constitutional disturbance and danger than if the surface of the trunk and face be extensively scorched to the first and second degrees. Burns about the trunk, the head, and the face, being far more likely to be attended by serious constitutional mischief than similar injuries of the extremities. In children the system generally suffers more severely from burns than in adults. The constitutional disturbance induced by burns, in whatever degree, may be divided into three stages: 1st, that of depression and congestion; 2d, of reaction and inflammation; and, 3d, of exhaustion and suppuration. 1st. The period of depression and congestion occupies the first forty-eight hours, during which death may occur before inflammatory action can come on. Immediately on the receipt of a severe burn, the patient becomes cold, collapsed, and is seized with fits of shivering, which continue for a considerable time ; he is evidently suffering from the shock of the injury; the severity of the shiver- ing is usually indicative of the extent of the constitutional disturbance induced by the burn, and is more prolonged in those injuries that occupy a great extent of surface, than in those which, being of more limited superficial extent, affect the tissues deeply. On the subsidence of the symptoms of depression, there is usually a period of quiescence before reaction comes on, and during this period the patient, especially if a child, not unfrequently dies comatose; death result- ing from congestion of the brain and its membranes, with, perhaps, serous effu- sion into the ventricles or the arachnoid. Besides these lesions, the mucous membrane of the stomach and intestines, as well as the substance of the lungs, are usually found congested. The pathological phenomena of this period are altogether of a congestive character. 2nd. The next period, that of reaction and inflammation, extends from the second day to the second week. In it irritative fever sets in early, with a degree of severity proportionate to the previous depression, and as this stage advances special symptoms commonly occur dependent upon inflammatory affections, more especially of the abdominal and thoracic viscera. Death, which is more frequent during this stage than in the preceding one, is usually connected with some inflammatory condition of the gastro-intestinal mucous membrane, or of the peritoneum. The lungs also are frequently affected, showing marked evidence of pneumonia or bronchitis; but the cerebral lesions are not so common as in the first stage; though when they occur they present more unequivocal evidence of inflammatory action. It is in this stage of burn, that that very remarkable and serious sequela, perforating ulcer of the duodenum, is especially apt to occur. Mr. Curling, who first attracted attention to it, explained its occurrence by the supposition that Briinner's glands endeavor by an increased action to compensate for the sup- pression of the exhalation of the skin, consequent upon the burn; and that the irritation thus induced, tends to their inflammation and ulceration. This ulcera- tion may, as Mr. Curling remarks, by rapidly proceeding to perforation, expose the pancreas, open the branches of the hepatic artery, or, by making a commu- nication with the serous cavity of the abdomen, produce peritonitis, and thus cause death. It usually comes on about the tenth day after the occurrence of the injury; seldom earlier than this. The only exception that I am acquainted with was in the case of a child nine years of age, who died on the fourth day after the burn, in University College Hospital, and in whom an ulcer, about the size of a shilling, with sharp cut margins, was found in the duodenum, the in- testinal mucous membrane generally being inflamed. That these ulcers are not invariably fatal is evident from a case mentioned by Mr. Curling, in which, on death occurring eight weeks after the injury from other causes, a recent cicatrix was found in the duodenum. These affections seldom occasion any very marked symptoms to indicate the nature of the mischief, the patient suddenly sinking. 338 BURNS AND SCALDS. In some instances there is hemorrhage, though this is not an unequivocal sign, as I have several times seen it happen from simple inflammatory congestion of the intestinal mucous membrane; pain in the right hypochondriac region and perhaps vomiting may also occur. 3rd. The period of exhaustion and suppuration, continues from the second week to the close of the case. In it we frequently have symptoms of hectic, with much constitutional irritation from the long continuance of exhausting discharges. If death occur, it is most frequently induced by inflammation of the lungs or pleura; affections of the abdominal organs and brain being rare during this stage of the injury. The influence of extent, degree, and situation, on the prognosis of burns has already been stated. The most fatal element indeed of these injuries is super- ficial extent. The cutaneous secretion being arrested over a large surface of the skin, congestion of the internal organs and of the mucous membrane must ensue; and hence death may happen directly from this cause, or from the super- vention of inflammation in the already congested parts; more particularly in the early periods of life, when the balance of the circulation is readily disturbed. The degree of burn rather influences the prognosis unfavorably so far as the part itself is concerned, than as the general system is affected. The most fatal period in cases of burn is the first week after the accident. I find that in 50 cases of death from these accidents, 33 proved fatal before the eighth day; 27 of these dying before the fourth day. Of the remaining 17 cases, 8 died in the second week, 2 in the third, 2 in the fourth, 4 in the fifth, and 1 in the sixth. The treatment of burns must have reference to the constitutional condition, as well as to the local injury. A vast variety of local applications have been recommended by different surgeons, such as flour, starch, cotton wadding, treacle, white paint, gum, solution of India rubber, &c.; the principle is, however, the same, viz., the protection of the burnt surface from the air. I shall here, how- ever, content myself with describing the method that is usually followed with much success at the University College Hospital. The constitutional treatment is of the utmost consequence. We have seen how death arises at various periods after these accidents from different causes, and we must modify our treatment accordingly. The first thing to be done after the infliction of a severe burn is to bring about reaction ; the patient is trembling in a state of extreme depression, suffering great pain, and may sink from the shock unless properly supported. A full dose (about thirty minims for an adult) of the liquor opii should be given at once in some warm brandy and water, and repeated, if necessary, in the course of an hour or two; to a child the dose must be proportioned according to the age. The burnt clothes having been removed, the patient should be laid upon a blanket, and, whatever the degree of the burn, be well covered with the finest wheaten flour by means of an ordi- nary dredger. The flour should be laid on thickly, but uniformly and gradually, forming a soft and soothing application to the surface. If the cuticle have been abraded or vesicated, the flour will form a thick crust by admixture with the serum discharged from the broken surface. If the skin be charred, the discharge, which will be speedily set up around the eschar, will take the flour on to the part, forming as it were a coating impervious to the air. The crusts thus formed should not be disturbed until they become loosened by the influence of the dis- charges of the part, when they should be removed; and the ulcerated surface that is exposed, dressed with water-dressing, red wash or lead ointment, accord- ing to the amount of irritation existing, the suppurating sore indeed being managed on ordinary principles. In some cases lint dipped in the " Carron oil," composed of equal parts of linseed oil and lime water, to which a small quantity of spirits of turpentine might be added, has appeared to agree better than any- thing else, and in others cotton wadding answers admirably. Whatever local application be adopted, I hold it to be of the utmost importance in the early stages of the burn to change the dressing as seldom as possible; not until it TREATMENT OF BURNS. 339 has been loosened, or rendered offensive by imbibition of the discharges. Every fresh dressing causes the patient very severe pain, and certainly retards materially the progress of the case. When the stage of reaction has fairly set in, the patient's secretions should be kept free by the administration of an occasional mild purgative and salines. Should any inflammatory symptoms about the head, chest, or abdomen manifest themselves, it will be necessary to have recourse to antiphlogistic treatment proportionate to their severity. I have certainly seen patients saved under these circumstances by the employment of blood-letting and the proper appli- cation of leeches. At a later period in the case, when the strength has been exhausted by the continuance and the amount of the discharges, good diet, quinine, and a general tonic plan of treatment will be required, and any symp- toms of hectic that supervene must be met in the ordinary way. As cicatrization advances, much attention should be paid to repressing the exuberant granulations by the free use of the nitrate of silver, and the position of the part must be carefully attended to, so as to counteract, if possible, the after-contraction that ensues. With this view, the part must be properly fixed by means of bandages, splints, and mechanical contrivances, specially adapted to counteract the tendency to contraction of the cicatrix. This is especially necessary in burns about the neck, when there is a tendency for the chin to be drawn down on to the sternum, and great deformity to be thus occasioned; and in burns at the inside of limbs or the flexures of joints, when after-contraction is very apt to ensue. In such cases I have advantageously employed the elastic traction of India-rubber bands to counteract the tendency to contraction of the scar. Operations for the removal of the effects of contraction, consequent upon burns, are occasionally required, and if judiciously planned and executed, may do much to remedy the patient's condition. The great obstacle to the success of these operations, however, consists in the fact that the granulations which spring from the contracted cicatrix are in their turn liable to take on the same contractile action as the original cicatrix. After the division of the cicatrix, also, it is often found that the subjacent structures have been so rigidly fixed in their abnormal position as not to admit of extension. It may then be neces- sary to divide some of these, as fasciae and tendons, before that part can be restored to its normal shape. These operations are most likely to be successful when they are practised for contractions at the flexures of the joints, as at the bend of the elbow, for in- stance. There, all that need to be done, is to divide the cicatrix down to the subjacent healthy structures, and then, by the proper application of splints or screw apparatus, gradually to extend the limb; if any muscles or tendons are found to offer resistance they may be divided, if this can be done without inflicting too serious a wound upon the part, and impairing its after-utility. Much caution, however, will here be necessary; for if the contraction be of old standing, the arteries and nerves will likewise have become shortened, and will be incapable of stretching under any force that it may be safe to employ. Operations that are undertaken for the removal of the disfigurements that occur about the face and neck as the result of burns, require much management. Instead of simple division of the cicatrix, it has been proposed to dissect it away entirely in some cases, in others, to transplant portions of healthy skin upon the surface thus denuded, or that results from the gaping of the wound during extension of the limb. In other instances, again, to divide it gradually by the pressure of a silver wire, passed through and twisted over it. In addi- tion to the division of the cicatrix, Mr. James, of Exeter, and Mr. Quain, have in these cases very successfully employed a screw-collar, by which the chin can be loosed from the sternum, and gradual extension of the cicatrix effected. Amputation may be required if the burn has destroyed the whole thickness of a limb; the part charred should then be removed at once, at the most con- venient point above the seat of injury; so also amputation may be required at 310 EFFECTS OF COLD. a later period, if, on the separation of the eschars, it is found that a large joint has been opened, and is suppurating, or if the disorganization of the limb is so great as to exhaust the powers of the patient in the efforts at repair. Great caution, however, should be employed in determining on the propriety of am- putating when the burn has extended, though in a minor degree, to other parts of the body, lest the powers of the patient be insufficient for the double call that will thus be made upon them. FROST-BITE. When the body has been exposed to severe or long-continued cold we find, as in the case of burns, that local and constitutional effects are produced. The local influence of cold is chiefly manifested on the extremities of the body, as the nose, ears, chin, hands, and feet, where the circulation is less active than at the more central parts. It chiefly occurs to an injurious degree in very young or aged persons, or in those whose constitutions have been depressed by want of the necessaries of life. In the first degree of frost-bite that calls for the attention of the surgeon, there is a feeling of stiffness, with complete numbness of the part that has been exposed to cold; it looks pale, has a bluish tint, and is somewhat shrunk. In this state the vitality of the part is not destroyed, but is merely suspended. On the return of circulation and the vital actions in the affected part, a burning tingling pain is felt, it becomes red, and shows signs of a tendency to inflamma- tory action. Indeed, this appearance of inflammation, often accompanied by a burning sensation, is probably the immediate consequence of extreme degrees of cold, as is experienced on touching solidified carbonic acid or frozen mercury. In the next degree of cold, the vitality of the part is completely destroyed; all sensibility and motion in it are lost, it becomes shrunken and livid; but though its vitality may have been annihilated by the immediate application of the cold, it is not until the part has become thawed that gangrene usually manifests itself; it then appears to do so by the violence of the reaction in- duced, the part rapidly assuming a black color, becoming dry, and separating eventually, as all other mortified parts do, by the formation of a line of ulcera- tion around it. The constitutional effects of a low temperature need not detain us. It is well known that after exposure to severe or long-continued cold, a feeling of heavi- ness and stupor comes on, which gradually creeps on to an irresistible tendency to sleep, which, if yielded to, terminates in coma, and a speedy, though pro- bably painless, death. The treatment of frost-bite consists in endeavoring to restore the vitality of the frozen parts. In doing this the great danger is, that reaction may run on to so great a degree as to induce sloughing of the structures whose vitality has already been seriously impaired. In order to prevent this accident occurring, the most gradual elevation of temperature must be had recourse to for restoring the part. The patient should be placed in a cold room, without a fire, any ap- roach to which would certainly lead to the destruction of the frost-bitten mem- ers. These must then be gently rubbed with snow, or cold water, and held between the hands of the person manipulating; as reaction comes on, they may be enveloped in flannel or woollens, and a small quantity of some warm liquid or spirit and water administered to the patient. In this way sensibility and motion will gradually return, often with much burning and stinging pain, red- ness, and vesication of the part. If gangrene have come on, or if the reaction run into sloughing, the sphacelated part, if of small size, may be allowed to detach itself by the natural process of separation ; if of greater magnitude, am- putation of the injured limb may be required. This should be done at the most convenient situation for the operation so soon as the line of separation has fully formed. DIVISION THIRD. SURGICAL DISEASES. CHAPTER XXIII. abscess. An abscess signifies a collection of pus occurring in any of the tissues or in- ternal cavities of the body. In structure, an abscess consists of an accumulation of pus situated in the midst of, and surrounded on all sides by a layer of fibrine deposited in and consolidating the neighboring tissues. This lymph, which constitutes the wall of the abscess, varies greatly in thickness and consistence, in some cases being scarcely perceptible, in others, some lines in thickness and of corresponding firmness, constituting, perhaps, the principal part of the mass. This wall of "limiting fibrine" is always very vascular, in consequence of the inflammation and congestion of the tissues that enter into its composition. Outside it there is an infiltration of sero-plastic matter, and beyond this again we reach the healthy tissue. Surgeons divide abscesses into various kinds, according to the symptoms attending them, their duration and cause. Thus they speak habitually of acute and chronic, hot and cold, lymphatic, diffuse, metastatic, and puerperal abscesses. The acute or phlegmonous abscess may be taken as the type of the disease. When it is about to form, the part which has been previously inflamed swells considerably, with a throbbing pulsatile pain; the skin becomes shining, glazed, and of a somewhat purplish-red. If the abscess be very deeply seated, the superimposed tissues become brawny and cedematous, without, perhaps, any other sign indicating the existence of pus. As the swelling approaches the surface it softens at one part, where fluctuation becomes perceptible, and a bulging of the skin covering its summit takes place; this pointing of the abscess indicates that it is about to burst, and discharge its contents, which it speedily will through a circular aperture formed in the skin. The pointing is an interesting pathological phenomenon, and takes place in the following way: — An abscess, originally formed perhaps deeply in the substance of a limb, enlarges by the extension of the periphery of its wall, and by the innermost layers of this structure at the same time degenerating into pus. As the wall extends, it has a special tendency to approach towards a free surface, whether that be external or internal, skin or mucous membrane; all the tissues between it and the surface towards which it is progressing being gradually absorbed or melting into the abscess. It is in this that the pointing essentially consists, and the mode in which it is finally accomplished would appear to be as follows: — the pressure that the tumor exercises from within outwards causes compression of those vessels, that, passing from the deeper parts, ramify between the summit of the abscess and the superjacent skin for its supply. In consequence of this pressure upon, and interference with, the (341) 342 ABSCESS. circulation through these vessels, the nutrition of the parts supplied by them is arrested, and they become softened, disintegrated in structure, and less resistant to the progress of the tumor than those tissues which surround it on other sides, and which have not had their vascular supply interfered with, or lost their normal cohesion. The abscess then naturally makes its way at this, the point of its circumference, where it meets with least resistance to its pro- gress. As it approaches the surface, the skin at first becomes more or less livid, tense, and cedematous, conditions indicating the interference with its circula- tion ; as the summit of the abscess presses upwards, the overlying skin loses its tension, and becomes relaxed; it then sloughs at the most central point, from which the cuticle has previously peeled off, and the outward pressure of the pus speedily detaching the slough, the abscess discharges itself. Though acute abscesses, if left to themselves, usually run this course and burst through the skin, the mucous or serous surfaces, or even into the interior of joints, yet some collections of pus, if very deeply seated, cannot find their way to the surface, but extend through the cellular planes of the limb in a lateral direction, bur- rowing and undermining parts to a great extent; or if situated in dense and unyielding structures, as in bone, are imprisoned within a case through which they may be unable to penetrate; in other rare instances, the abscess disappears by the pus becoming absorbed. After an abscess has burst, the cavity usually closes by granulations springing up from within, and by the collapse of its walls; in some cases, however, it does not completely close, but contracts into a narrow canal, forming a sinus or fistula. Chronic abscesses are of very common occurrence, a piece of dead bone having given rise to irritation in its vicinity, or a gland, or some portion of the subcu- taneous cellular tissue having become indurated, tender, or subacutely inflamed, at last slowly and without any constitutional symptoms, or much appearance of local disturbance except the swelling, softens and breaks down into a somewhat thin, flaky, curdy, puriform fluid, though in other instances the pus is perfectly healthy. These abscesses do not readily point, but often extend laterally, bur- rowing for a considerable distance from their original seat. In other cases they become circumscribed by a thick and dense wall of fibrine, through which it may be extremely difficult, and perhaps impossible, to detect fluctuation, the disease then simulating a solid tumor. The duration of these chronic abscesses with- out opening, is often very remarkable, even when situated in soft parts. I have seen large chronic abscesses in the iliac fossa and groin, perfectly stationary for nearly two years. When situated in denser structures, as in the substance of the breast for instance, the wall may become so dense as to resemble a cyst, and the disease will continue in the same state for a great length of time. In the bones, abscesses may exist for an indefinite period. The cold, lymphatic or congestive abscess occurs not unfrequently with but very slight precursory local symptoms, and indeed not uncommonly without any at all. The patient, who has usually been cachectic, and suffering some time from general debility, after feeling slight uneasiness in the groin, iliac fossa, or axilla, finds suddenly a large fluctuating tumor in one or other of these situa- tions ; there is perhaps no pain in the part, and no discoloration of the skin, but the fluctuation is always very distinct, the limiting fibrine being in small quan- tity. On opening such an abscess as this, there will usually be a copious dis- charge of thin unhealthy pus, which when examined under the microscope will be found to contain ill-developed, withered cells; in some cases the con- tents appear to be a clear semi-transparent or oily-looking matter, probably sero- plastic effusion. Diffuse abscess^ forms rapidly in the cellular tissue, as the result of diffuse inflammation of it. In these cases there is no limiting fibrine, and hence the pus often spreads widely, producing extensive destruction of parts beforejt is discovered. A particular variety of this form of abscess is the puerperal, occur- ABSCESS, VARIETIES OF. 343 Fig. 185. ring in women after parturition, in various parts of the body, especially in the iliac fossa, the cellular planes of the thigh or in the joints, and in the adipose tissue of the orbit, often destroying the globe of the eye. To these forms of the disease the metastatic abscesses are closely allied. They commonly occur in connection with phlebitis and pyemia, are very numerous, and are met with in the substance of organs as well as the cellular tissue and joints. The three last species of abscess are varieties of the acute form. The tympanitic or emphysematous abscess, which contains gas as well as pus, is occasionally met with in the neighborhood of the mucous canals, chiefly at the ante- rior and lateral parts of the abdominal walls and about the sacrum. Sometimes the com- munication with the intestine is very free, in other cases it is not so evident. These collections are often perfectly resonant on percussion, the air being above, the fluid below, and sometimes gurgling, is very dis- tinct in them. Abscesses are met with in all regions of the body, but more especially in the cellu- lar tissue; partic J&py in those parts where this tissue is aburmant, and the absorbent glands are numerous. They may occur at any period of life, from the earliest infancy to old age. I have opened a very large ab- scess in the axilla of a. child about a fort- night old. Their size varies from that of a pin's point to a tumor containing a pint or more of pus. In some cases when very large they are multilocular, the different cysts being connected by narrow channels of communication; in this way I have seen a large abscess extending from the lumbar vertebrae through the iliac fossa down the thigh, the ham, and the leg, until at last it was opened by the side of the tendo Achil- lis, forming five or six distinct cysts, com- municating with one another by contracted channels (fig. 135). The pressure-effects of abscess are often important. By compressing the nerves of a part it may give rise to very severe pain and spasm at a distance from its seat, and in this way in some apparently neu- ralgic affections it has turned out that the pain has been occasioned by the pres- sure of an abscess on the trunk of a neighboring nerve. When blood-vessels come into relation with an abscess, they usually become coated by a thick layer of lymph, which guards them from injury. In some cases, however, they become obliterated by the conjoined effects of the pressure and the inflammation, in which they partake as well as the adjacent tissues. In other cases, more par- ticularly in strumous and cachectic individuals, the blood-vessels not having been guarded by the protecting lymph, have ulcerated and burst into the cyst of the abscess, occasioning sudden, dangerous, or even fatal hemorrhage. It is seldom, however, that a large artery or veins pours its contents into an abscess that had not been opened. The various mucous canals, more especially the trachea and the urethra, may be injuriously compressed by neighboring ab- 344 ABSCESS. scesses ; so also bones may become necrosed, and joints inflamed and destroyed, from the same cause. The diagnosis of abscess, though usually easily made, at times requires attention. The surgeon believes that an acute abscess is about to form when, after rigors and some modification of the inflammatory fever, he finds the local signs characteristic of the formation of pus; more especially a throbbing pain in the part, with softening of any induration that may have existed, and oedema of the cellular tissue covering it. His suspicion is turned to certainty, and he knows that an abscess has'formed, when, after the occurrence of these symptoms, fluctuation can be felt, and the other signs manifest themselves. This fluctua- tion may, however, readily be confounded with the undulatory sensation that is communicated by some tissues from the mere infiltration of sero-plastic fluid into them, or even without this, from their natural laxity, as is sometimes the case in the cellular tissues of the nates and thigh in persons of lymphatic temperament. This, indeed, is a difference of degree rather than of kind, as pus would make its appearance in the course of a few hours, if the tumor were left to itself. The mere occurrence of fluctuation is not of itself sufficient to determine more than that a fluid exists in the part. The question necessarily arises, is this fluid pus? In the majority of instances the history of the case, the character of the pain, the previous existence and the continuance of symp- toms of inflammation, enable the surgeon to answer in thefaffirmative. But if there be but obscure evidence of inflammation having existea^and if the swelling be of long standing, the fluctuation being perhaps deeply seated and indistinct, the safer plan will be for the surgeon to introduce an exploring needle, and to see what the true nature of the fluid is; by this simple means many embarrass- ing mistakes in diagnosis may be avoided. The tumors with which abscesses may be confounded, are those soft solid growths in which there is a high degree of elasticity, giving rise to a species of undulation, as in some kinds of encepha- loid tumor; so also fluid tumors of various kinds, such as cysts and enlarged bursae, may be confounded with abscess. In these cases the previous symptoms, the situation, and the general appearance and feel of the tumor, will usually enable the surgeon to effect a ready diagnosis; but should any doubt exist, the exploring needle or trochar must be introduced, when* the escape or not, of a drop or two of pus will determine the question. Coxeter's " suction trochar" Fig. 136. (fig. 136), is of especial service in cases in which it is desirable to withdraw some of the contained fluid for closer examination. The diagnosis of an abscess having pulsation communicated to it by a subjacent artery, from an aneurism, will be discussed when we come to speak of that disease. It may be well to mention that the pains occasioned by the pressure of some forms of chronic abscess upon neighboring nerves have been mistaken for rheumatism. Abscesses vary greatly in danger, according to their nature, size, situation, &c. The chronic form is usually attended by more risk than the acute and the diffuse. The puerperal and pyemic are especially hazardous to life, being gene- rally associated with a bad state of the blood. The large size of some abscesses is an element of great risk, occasioning not only a very abundant discharge of pus, but likewise great constitutional irritation when opened. Abscesses that are situated in the neighborhood of important organs, as about the neck of the ABSCESS, VARIETIES OF. 345 bladder, or in the anterior mediastinum, are necessarily much more hazardous from the peculiarity of their situation than those which are met with in less important regions. The cause of the abscess also influences the result; if it be a piece of dead bone that can be removed, the discharge will speedily cease on its being taken away, but if it be so situated that it cannot be got rid of, it will, by acting as a continuous source of irritation, keep up a discharge that may eventually prove fatal. The constitution of the patient influences our prognosis. Such an amount of discharge as would inevitably prove fatal in a cachectic system, may influence a sound one but very little; so also, the wasting effect of the abscess is better borne about the middle than at either of the extreme periods of life. The treatment of abscess presents three points requiring attention. The first object should be to prevent the formation of matter; the next, to take steps for its evacuation when formed; and, lastly, to endeavor to close the cavity that results. In order to prevent the formation of matter, it is necessary to get rid of any local irritant that may exist; thus dead bone should be removed, or extravasated urine let out of the cellular tissue. After this has been done, the preventive treatment must consist in the active employment of local antiphlogistic means, such as leeches andf^ld evaporating lotions: any slight tenderness that con- tinues after the innjmarnation has subsided must be removed, and that swelling from exudation maror, which is especially the precursor of chronic abscess, must be got rid of by the continuous application of some discutient lotion. One composed of iodide of potass, 3 i., spirits of wine, 3 i-, water, § vij., is extremely useful; in some cases absorption may advantageously be promoted by mercurial ointments or plasters. When once pus has formed, it is a question whether it can be absorbed again; in general, it certainly cannot, more especially if once a distinct cyst has formed around it; but in some cases it may undergo absorp- tion ; thus, in hypopium, we occasionally observe that the pus deposited in the anterior chamber of the eye is removed, and I think it probable that the same may happen when it is infiltrated into the tissues of a part, without a very dis tinct wall surrounding it. The more fluid parts of chronic abscesses occasionally become absorbed, leaving a cheesy residue behind, which may degenerate into cutaceous matter. When, notwithstanding the employment of antiphlogistic means, it is evident that pus is about to form, the treatment should be completely changed, and by the aid of warmth and poultices, an endeavor should be made to hasten suppu- ration. When this is fully established, the abscess having become " ripe," steps must be taken for the evacuation of the matter. The treatment of acute and of chronic abscesses differs essentially in this respect. In the acute abscess the matter should be let out as soon as it is fully formed, especially in those varieties of the disease connected with a morbid state of the system, as in the metastatic and puerperal forms. When this is done, the con- stitution at once experiences great relief, the fever and general irritation sub- siding materially; the free incision by which this is accomplished not only letting out the pus and lymph, but removing tension, and by encouraging local bleeding, lessening the inflammatory action. The rule of opening an acute abscess early is especially imperative when the pus is formed in the sheaths of the tendons and under fibrous expansions, as in the palm of the hand; so, also, when it is situated deeply in the cellular planes of a limb, under the larger muscles, where it has a tendency to diffuse itself extensively. In those cases likewise in which it is lodged in close proximity to a joint, or under the peri- osteum, it must be let out early; so also when it presses upon mucous canals or important organs, as on the urethra or trachea, or when it is dependent on the infiltration of an irritant fluid into a part, as by urinary extravasation, it must be evacuated without delay. The pus should always be let out early before the 346 ABSCESS. skin covering it is thinned, when the abscess is situated in the neck or in any other part where it is desirable that there should be as little scarring as possible. In the case of chronic abscesses, the rule of surgery is not so explicit. Here the collection is often large, coming on without any very evident symptoms, and giving rise to no material inconvenience; but if it be opened, putrefaction of the pus, consequent upon the entry of air into the extensive cyst, will give rise to the most serious constitutional disturbance, setting up irritative fever that may rapidly prove fatal in a debilitated frame, and should the patient escape this danger, the drain of an abundant suppuration may speedily waste him. Hence, it not uncommonly happens that a patient may carry a chronic abscess unopened, without any very serious disturbance, for many months or even years, but when once opened, that he will die in a few days. If, however, the chronic abscess be so small that no danger is to be apprehended from the inflammation of its cyst, or if it be situated in parts where its presence may give rise to dan- gerous pressure, the matter should be let out without delay. There are three modes by which abscesses may be opened, each of which possesses advantages in particular cases: — these are by incision, by tapping with a trochar, and by making an aperture into the cyst with caustic. Incision is the only plan that should be practised i-a^mxite abscesses. For this purpose a lancet, an abscess-bistoury (fig. 137), or a^^Hpe-shaped knife may be used. The incision should be made either at the pornt where fluctuation is most distinct, or at the most dependent part of the tumor, so as to prevent after-bagging of the matter. It should be made by holding the bistoury or Fig. 137. lancet short, and introducing it perpendicularly into the softened part. If the depth to be reached is considerable, a bistoury should be used, the blade of which should be half turned round after its introduction, when the pus wells up by its side, the point being felt to move freely in the cavity of the abscess. The incision must then be continued for a moderate extent in the direction of the natural folds of the skin of the part, or in the course of the vessels. The pus should be let out freely, so as to allow the walls of the abscess to collapse, but it should not be forced out by squeezing the sac. It may happen, after the escape of the pus, that the cavity of the abscess fills with blood by the rupture of some small vessel situated in its wall; this, however, is of little moment, the hemorrhage speedily ceasing on the application of pressure, of a bandage, or of cold. After the opening has been made, a poultice or water-dressing must be applied; the cavity left, eventually fills up either by the coalescence of its sides, or by granulating from below; if it fill again with pus, a fresh incision, termed a "counter-opening," must be made in the most dependent part. In the treatment of chronic and cold abscess, all three plans may be employed for opening the sac. If it be of small size, an incision should be made into it at once. If the collection be considerable, we must wait until an opening has been rendered necessary by the tendency to implication of the skin, or by inju- rious pressure being exercised on important parts; the pus should then be let out by the valvular aperture recommended by Abernethy, the object being to limit the entry of air into the interior of the abscess, to lessen the chance of putrefaction of any pus that is left, and of consecutive inflammation of the cyst. The valvular opening is made by drawing the skin covering the abscess well to one side, then passing the bistoury directly into the sac, and allowing as much OPENING OF ABSCESSES. 347 of the pus to escape as will flow out by the collapse of the walls of the abscess; before the matter has quite ceased to flow, and before any air can consequently have got into the sac, the skin should be allowed to recover its natural position, bo that the aperture in it and in the cyst may no longer directly communicate. A piece of plaster, or of lint soaked in collodion, should be placed upon the external wound, which will probably heal under this covering in the course of a short time. When the cyst of the abscess has again filled somewhat, this process may be repeated; and less and less pus being allowed to accumulate in it before each succeeding evacuation, it may gradually contract and close. Instead of making the valvular opening in this way, a chronic abscess may sometimes be advantageously opened by tapping with a trochar and canula of moderate size, the instrument being introduced obliquely between the skin and the abscess, and then made to dip down into the sac. After the withdrawal of the canula, the aperture may be closed as in the former case. There is, how- ever, one disadvantage in this plan of opening abscesses; that if the discharge be curdy or shreddy, it is very apt to block up the canula, and thus to interfere with the proper evacuation of the matter. The potassafusa, though a painful application, may be advantageously used for opening those chronic abscesses, the skin covering which is much under- mined, congested, aj^ discolored. In these cases I commonly employ it with great advantage. ^Hfs also useful in the after-treatment, when much solid plastic matter is ler^Dy dissolving this away, and thus preventing the formation of sinuses. In some forms of abscess it will be found that those processes which are necessary for the contraction and closure of the cyst, after its contents have been evacuated, do not readily take place; and it becomes necessary to have recourse to other measures, in order to excite sufficient healthy inflammatory action, to occasion the deposition of that plastic matter by which the cavity is filled. With this view, a seton of two or three threads may very usefully be passed across the cyst by means of a naevus needle, or by a long straight needle pushed up through the canula used for tapping (fig. 138). It should be left in for a few days, by which time healthy inflammation will be set up. In other cases again, after the cyst has been tapped, the red wash or some tincture of Fig. 138. iodine should be injected and left in. These methods of exciting inflammation are especially useful when the cyst is thin, and of a very chronic character. When the walls are very thick and dense, as sometimes happens in abscesses of very old standing situated in the neck, an elliptical piece of the anterior portion of the cyst should be dissected out, and the remainder of the cavity, lightly dressed with lint, be allowed to fill by granulation. This plan of treatment is often very successful, and I have in this way cured abscesses in the neck of seven or eight years' standing, which have resisted every other plan employed. The constitutional treatment of abscess must be conducted on the general principles laid down in discussing the management of suppurative inflammation 348 ABSCESS. (p. 97); but it must be borne in mind, that as abscess is always a disease of debility, a tonic and stimulant plan will early be required. SINUS AND FISTULA. After an abscess has been opened, its cavity may not fill up completely, but contracting into a narrow suppurating track, forms a canal without disposition to close, and from which a small quantity of pus constantly exudes, thus consti- tuting a sinus or fistula. The cause of this non-closure of the cyst of an abscess may be referred to the following heads: — 1st. The presence of a foreign body, as of a piece of dead bone at the bottom, may keep the track open; 2d. The passage of irrita- ting secretions, as of urine, faeces, saliva, &c, through the abscess, will prevent its complete closure; and 3d. The contraction of neighboring muscles will occasionally prevent the due coalescence of the sides of the abscess; as when it is in the neighborhood of the sphincter ani, and as may occasionally happen in abscesses about the limbs. A sinus or fistula consists of a narrow channel, often long and winding having an external orifice that is usually somewhat protuberant, being situated under or in the midst of loose florid granulations. Th^wfells of this channel, which are always indurated, are lined by a structure reBBbling mucous mem- brane ; this, however, it is not, but simply consists of {Wayer of imperfectly- formed granulations, exuding ichorous pus. If the orifice be occluded, this pus will collect within the sinus, and distending its walls, reconvert it into an abscess. In structure, therefore, a sinus or fistula may be said to be a Ion"- narrow, chronic abscess, with a permanent external aperture. The treatment of a sinus or fistula has reference to its cause in the first instance ; for until the foreign body that keeps it open and maintains the discharge is removed, it will be useless to attempt its closure. After its removal, we may endeavor to procure obliteration of the sinus by one of three methods. 1st. The employment of pressure, by means of a roller and graduated compresses, so as to cause an agglutination of its opposite sides. This plan is useful in those cases in which the sinus is recent, without much surrounding induration, and so situated, as upon the trunk, that pressure can easily be applied. 2d. A more healthy inflammation may often usefully be excited in the sinus, by injecting it from time to time with red wash, or with tincture of iodine, by passing the threads of a seton through it, or stimulating it by the occasional contact of a red-hot iron. My colleague, Mr. Marshall, has invented a very ingenious and useful apparatus, by means of which a platinum wire, introduced cold, is heated red-hot by the galvanic current. This plan of treatment, which is fully detailed in a paper published in the " Medico-Chirurgical Transactions" for 1851, has frequently been employed with much success in the University College Hospital in the treatment of fistulae and sinuses to which other methods were not very applicable. 3d. The last method consists in laying open the sinus from end to end, and then dressing the wound so that it may heal from the bottom; in this way neighboring muscles, that have kept it open by their contractions, may also be set at rest. The division of the sinus should be done with a probe-pointed bistoury, introduced through the external opening either by the aid of a director or without such assistance. The operation should be done effectually, the sinuses being usually followed as far as it is prudent to go, and laid completely open. VARIETIES OF ULCERS. 349 CHAPTER XXIV. ULCERS. Various forms of ulcer, affecting the cutaneous surface or mucous mem- branes, are familiar to the practical surgeon. When occurring in the skin, as the result of non-specific disease, they may be arranged under the following heads : the Healthy—the Weak—the Indolent—the Irritable—the Inflamed— the Phagedenic or Sloughing—the Varicose—and the Hemorrhagic. Besides these varieties, each of which is marked by distinct characteristics, various other forms of ulceration depending on specific causes, as the syphilitic, scrofu- lous, lupoid, cancerous, &c, are met with, all of which will be treated under their respective chapters. The varieties presented by ulcers are by no means dependent on local condi- tions merely, though these influence them greatly, but are in a great measure owing to constitutional causes. Indeed, the aspect of an ulcer, the character of its granulations and of its discharge, are excellent indications of the state of health and of the general condition of the patient, as well as of the local disease that exists. yf Ulcers may be situated upon any part of the cutaneous surface as the result of violence; most commonly when occurring from disease of a non-specific character, they are seated on the leg, but when arising from some specific affection they occur in particular situations, as on the penis, lips, &c. The healthy or purulent ulcer may be considered the type of the disease, presenting a circular or oval surface, slightly depressed, thickly studded with small granulations exuding laudable pus, and having a natural tendency to contract and heal. It is the object of all our treatment to bring the other forms of ulcer into this condition. In the management of this healthy ulcer, the treatment should be as simple as possible, water-dressing and the pressure of a bandage usually enabling it readily to cicatrise. The weak ulcer not uncommonly occurs from emollient applications having been continued for too long a time to the last variety of the disease, the granu- lations then becoming high and flabby, with a semi-transparent appearance about them, and sometimes rising in large, exuberant, gelatinous, reddish- looking masses above the surface of the sore. These high granulations have a feeble vitality, and readily slough. The treatment of this form of ulcer consists in keeping the part elevated and carefully bandaged, with an astringent dressing to the sore; such as a weak solution of the sulphate of zinc or of copper, or the " red wash," according to the following formula: — Sulphate of zinc, grs. xvj.; comp. tinct. of lavender and spirits of rosemary, of each jtij.; water §viij., will be found a most useful application, in addition to touching the granulations from time to time with the nitrate of silver. The indolent ulcer is always of a very chronic character; it is situated upon the outer side of the lower extremities, between the ankle and calf, and most frequently occurs in men about the middle period in life. It is deep and exca- vated, with a flat surface, covered by irregular and badly-formed granulations, exuding a thin and sanious pus, having hard, elevated, and callous edges, and presenting generally an irregular and rugged look. The surrounding integument is congested and matted to the subjacent parts; there is usually very little subcutaneous cellular tissue about it, the skin being firmly fixed to the subjacent fascia; and it would appear as if it were in consequence of this want of a vascular substratum from which to spring, that granulations do not readily arise. There is no pain attending this ulcer, and its surface, which often attains a very large size, may usually be touched without the patient feeling it. The principle of 350 ULCERS. the treatment here is two-fold, to depress the edge, and to elevate the base of the sore. This is effected by pressure and stimulation conjoined. The treat- ment should be commenced by rubbing the surface of the ulcer and the sur- rounding congested integument with nitrate of silver; a linseed-meal poultice should then be applied for twenty-four hours, after which the sore should be properly strapped on the plan recommended by Baynton. The best plaster for this purpose is the emplastrum saponis, to which some of the empl, resinee is added to make it sufficiently adhesive; this, spread upon calico, should be cut into strips sixteen or eighteen inches in length and about an inch and a-half in width; the centre of the strip should then be laid smoothly on the side of the limb opposite to the sore, and its ends being brought forward, are to be crossed obliquely over it. Strip after strip must be applied in this way until the limb is covered for a distance of a couple of inches above and below the ulcer. If the sore* be near the ankle, this joint should be included in the strapping. Each strip of plaster should be applied with an equal degree of pressure, which may often be considerable, and should cover at least one-third of the preceding strap; the limb must then be carefully bandaged from the toes to the knee. Under this plan of treatment, the edges will subside, the surface of the sore become florid, and granulation, yielding abundant discharge, speedily spring up. Much of its success will depend upon the dpse attention that is paid to the case; if the skin be irritable, no resin-plast^rshould be used, but merely the soap or lead, and the plasters should be changed at least every forty- eight hours. If the discharge be very abundant, small holes should be cut in the strips to allow it to escape. When by this plan of treatment the edges of the sore have been brought down, and the granulations sufficiently stimulated, an astringent lotion with bandaging may advantageously be substituted for the plasters. In some of these cases I have found benefit from the internal administration of liquor arsenicalis. The irritable ulcer is mostly met with in women about the middle period of life, more especially in those of a nervous and bilious temperament. It is usually of small size, and situated about the ankles, or upon the shin. Its edges are irregular, but not elevated, the surface greyish, covered with a thin slough, and secreting unhealthy sanious pus. Its principal characteristic is the excessive pain accompanying it, which often, by preventing sleep, disturbs seriously the general health. In the treatment of this ulcer we must attend to the constitutional as well as the local condition. The patient should be put upon an alterative course of medicine, with aloetic purgatives and some sedative at bed-time to procure rest. The mode of topical medication that I have found to succeed best is to brush the surface of the sore and the surrounding parts from time to time with a strong solution of the nitrate of silver, and then to keep emollient and sedative applications to it, such as lead and opium lotions. The occasional application of the nitrate of silver deadens materially the sensibility of the sore and assists its granulation. The inflamed ulcer is characterized by much redness, heat, and swelling of the surrounding parts, with a thick and offensive discharge, often streaked with blood; it may come on from the over-stimulation of one of the other varieties. The treatment must be locally and generally antiphlogistic. The elevated position, the application of leeches around the sore, and of cold evaporating lotions to the surface of the limb, will speedily subdue the inflammatory action, after which, the healing process takes place with great rapidity. The sloughing ulcer, when not specific, is an increased degree of the inflamed variety, usually occurring in a feeble or cachectic constitution, and generally accompanied by a good deal of fever of the irritative type. An angry dusky red blush forms about the sore, which becomes hot and painful; the surface assumes a greyish sloughy look, the edges are sharp cut, and the ulcerative action extends rapidly. The treatment in these cases should consist VARIETIES OF ULCERS. 351 in improving the general health by lessening irritation, and keeping up tone. The administration of opiates with nourishing but unstimulating diet, should be trusted to at the same time that the local action is subdued by rest and warm opiate lotions. When the inflammatory condition has subsided, tonics should be given internally, and a grain or two of the sulphate of copper or of zinc may be added to the lotion with which the sore is dressed. The specific varieties of sloughing ulcer will be considered in the chapter on Hospital gangrene, &c. The varicose ulcer derives its chief characteristic from being complicated with, or dependent upon, a varicose condition of the veins of the leg. In this affection of the venous trunks the skin gradually undergoes degeneration, becoming brawny, of a purplish brown color, and being traversed in all directions by enlarged and tortuous cutaneous veins. The ulcer forms at one of these congested spots, by the breaking down of the already disorganized and softened tissue, forming a small irregular chasm of an unhealthy appear- ance, and varying much in character, being sometimes inflamed, at others irritable or sloughy, and then becoming indolent. One of the most serious effects of this ulcer is, that by penetrating into one of the dilated veins it occasionally gives rise to very abundant hemorrhage, the patient, in the course of a few seconds, losing a pint or two of blood. This hemorrhage may be readily arrested by laying the patient on his back, elevating the limb, and compressing the bleeding point with a pledget of lint and a roller. The treatment of a varicose ulcer must have special reference to the condition of the veins that occasions it; no local applications having much effect unless the pressure of the column of blood in the dilated vessels be taken off the part. This may be done by means of a well-applied bandage, made of elastic material, or a laced or elastic stocking applied to the leg, so as to keep up a uniform pressure upon the distended vessels. In some cases, the length of the column of blood may be broken by the application of a vulcanized india-rubber band below the knee. In many cases the cicatrizations of the ulcer cannot be brought about in this way, or, if it heal, it will constantly break open again; or hemor- rhage may have occurred from a ruptured vein upon its surface: means must then be taken for the permanent occlusion of the varicose vessels by their ligature, as will be described in the chapter on those affections. As this pro- cedure, however, is attended by some danger from the occasional induction of phlebitis or erysipelas, it should not be had recourse to unless the existence of one or other of' the conditions just mentioned urgently calls for it. The hemorrhagic ulcer is a dark, purplish-looking sore, occurring in women suffering from amenorrhcea, and having a special tendency, whence its name, to ooze blood about the menstrual periods; it usually partakes of the character of the irritable ulcer, and requires to be treated by constitutional means, having for their object the improvement of the patient's general health; with this view the preparations of iron and aloes are especially useful. Various forms of ulcer occur upon the mucous membrane of the throat, rectum, and genital organs. As these, however, are commonly of a specific character, they will be hereafter described. When ulcers of the mucous membrane are not of a specific character, they present the general appearances characteristic of the cutaneous, healthy, inflamed, or weak varieties, and require the topical applications suited to these conditions; though generally they will bear and require the free employment of caustics, especially of the nitrate of silver. 352 MORTIFICATION, OR GANGRENE. CHAPTER XXV. MORTIFICATION, OR GANGRENE. The local death of a part of the body, in surgical language, is termed Morti- fication or Gangrene: when the morbid action is confined to the osseous structures or to tne cartilages, it is termed Necrosis; when limited to the soft tissues of a limb, Sphacelus; and when accompanied by ulceration, it is called Slough. Many other varieties of gangrene are recognized by surgeons; like all other diseases, it may be acute or chronic in its duration; as the parts affected are moist and swollen or dry and shrivelled, it may be divided into the moist and the dry or mummified gangrene; so, again, according to its cause, it is spoken of as idiopathic or traumatic, and very frequently and most correctly, perhaps, arranged under the denominations of constitutional and local, without reference to the comparatively accidental circumstances of its dryness or moisture. Besides these, various specific forms of the disease are met with, which will require special consideration. Whatever form the gangrene may assume, there are certain local phenomena that are common to all the varieties of it. There is complete loss of sensibility and of motion in the part affected, the temperature of which falls considerably below that of the body generally, giving rise to a sensation of damp and clammy coldness, and after a time there is an odor of putrescence evolved, with very commonly an emphysematous crackling from effusion of gas into the tissues of the part. The color of the part affected is usually of a dark purplish or greenish-black, more or less mottled with red. This, which is unlike anything else in the system, shows that changes of importance have taken place in the solids and fluids of the diseased tissues, and is usually con- nected with the moist and swollen form of the disease. In the dry variety of gangrene, the color is often at first of a pale tallowy-white, with a mottled appearance upon the surface. The skin soon shrivels, becomes dry, horny, and semi-transparent, and eventually assumes a brown, wrinkled appearance; in other cases, again, the gangrened part is brown, dry, and shrivelled from the very first. These differences in the color of the mortified part indicate corresponding differences in the cause of the affection. In general terms, it may be stated that the dark varieties of gangrene are the result of destructive changes taking place in the very part itself, or are of constitutional origin, whilst the pale form of the affection occurs as a consequence of some obstruc- tion in the supply of blood to the part, and is a local disease only, influencing the constitution secondarily. The processes adopted by nature for the arrest of gangrene, by the formation of a line of demarcation, and for the detachment of the parts that have lost their vitality, by the extension of ulceration along the line of separation, have already been fully described (pp. 103,104). The constitutional symptoms vary greatly: when the disease is strictly local, affecting a part of but limited extent, and of no great importance, perhaps, to the economy, they are not very strongly marked. If, however, the gangrene, although limited, implicate organs of importance to the system, as a knuckle of intestine, for example, marked symptoms declare themselves. Whatever the precursory condition may be, the full invasion of the gangrene, if it be of rapid occurrence, is always accompanied by constitutional disturbance of an asthenic type, attended by great depression of the powers of the system, with a dull and anxious countenance, and a feeble, quick, and easily compressible pulse; the tongue is brown, and soon becomes loaded with sordes. When the VARIETIES OF GANGRENE. 353 gangrene is internal, a sudden cessation of pain, with hiccup, vomiting, and tympanitic distension of the abdomen, may be superadded to the symptoms, and indicate the mischief that has occurred. Death usually supervenes with low delirium, twitchings, and coma. When the invasion of the gangrene is more gradual, as we see in some of the constitutional forms affecting the lower extremities, the symptoms are usually those of irritative fever, eventually sub- siding into the asthenic form. The diagnosis of gangrene is easily effected when this condition has fully developed itself; but in the early stages, before it is positively declared, it is not always an easy matter to determine its existence. The ecchymosis and discoloration of a bruise, the collapse and lividity that result from cold, or the dark purple hue occasioned by long-continued congestion, may readily be confounded with impending gangrene. In these cases of doubt, the surgeon should not be in too great a hurry to pronounce an unfavorable opinion, and still less to act upon it, for it not uncommonly happens that parts of the body that had to all appearance lost their vitality, may by proper treatment regain it. The prognosis of gangrene is always bad, so far as the part itself is con- cerned, though it occasionally happens that when it is not fully established, partial recovery may unexpectedly take place. So far as the life of the patient is at stake, much will depend on the cause of the affection, and the age and strength of the individual in whom it occurs. At advanced periods of life, and in a feeble state of system, the result is always unfavorable; so also whilst the gangrene is spreading, the prognosis is bad, as it is impossible to say where the morbid action may stop; but when once the line of demarcation has formed, indicating as this does the possession of a certain vigor of constitution, the principal danger is over, and then the result will depend on the power of the patient, and the support that can be given during the processes of separation and of repair. The causes of gangrene are very various. They may be arranged under four principal heads: 1st. The intensity or specific nature of the inflammation of a part may give rise to its death by the stagnation of the blood within its vessels, or by inducing such changes in it as are incompatible with life. 2d. The arrest of the circulation through a part is a common cause of gan- grene, and may be occasioned in one of three ways; either by strangulation of the part generally; by the obstruction of the flow of blood through the main arteries leading to it; or, by the return of blood through the principal veins coming from it being interfered with. 3d. Traumatic causes of various kinds give rise to different forms of gan- grene, most of which we have already considered. Thus the severe contusion, compression, or laceration of a part may occasion gangrene of it (page 116); the infiltration of an irritating fluid into a part; and, lastly, its exposure to intense heat or cold will destroy the vitality of the tissues implicated. 4th. Specific poisons of various kinds occasion special diseases, of which gan- grene is the principal characteristic. Thus hospital gangrene, malignant pus- tule, noma, carbuncle, and ergotism, are instances of specific affections, accom- panied by gangrenous action. Amongst the causes, some are constitutional, others, local, in their action : — those forms of gangrene are said to be constitutional which arise from intense or specific inflammation of the part—from obstruction of the circulation in con- sequence of a diseased state of the heart and vessels, or from the action of various specific poisons. On the other hand, those varieties of gangrene are local which arise from injuries of all kinds, whether applied to the part itself, or to the main artery leading to it, by its ligature or wound. Some of the varieties of gangrene that have just been indicated, such as those arising from the intensity of the inflammation, and from various traumatic 23 354 MORTIFICATION, OR GANGRENE. causes, have already been discussed (p. 116); whilst those that arise from ob- structed circulation, or that take the form of specific diseases, are left for our consideration here. Gangrene from Arrest of Circulation.—Arrest of circulation may act in three ways in inducing gangrene : — 1st, by the arrest of all the blood, arte- rial, venous, and capillary, in the part, as in strangulation by a tight ligature; 2d, by obstruction of the arteries, and consequent deprivation of blood; and 3d, by venous obstructions, and by consequent over-accumulation of blood. 1st. A part is often purposely strangled by a surgeon in many operative pro- cedures, or its circulation may in this way be arrested, as the result of certain diseased conditions. In either case, the strangulation acts by stopping more or less completely the whole circulation of the part. If it be sufficiently severe, it may kill the tissues outright; as, for instance, when a naevus or pile is tied, all flow of blood to or from the part is suddenly arrested, and its vitality destroyed, the tissues that have been strangled shrivelling, and separating by ulceration along the line of ligature. When the strangulation is not so severe as this, great congestion in the part ensues, consequent on the interference with the return of the venous blood; the part strangled becoming dark and congested, phlyctenas or vesicles arising on its surface, and effusion taking place into its tissue. Inflammation becoming at last superadded to the effects of the strangu- lation, and still more embarrassing the circulation of the part, sloughing takes place by the conjoined action of the strangulation and the inflammation; all this we see occurring in a constricted gut. 2d. Arterial obstructions.—When a part of the body is deprived of its proper supply of blood, mortification may ensue. This we see occasionally happen when the circulation is arrested through the main artery of a limb by its liga- ture or wound. Most commonly, when the principal trunk of an artery is ob- structed, the collateral circulation is sufficient to maintain the vitality of the part; but should this be interfered with in any way, gangrene ensues from the simple deprivation of that blood which is necessary to the maintenance of its life. Indeed, the sudden loss of a large quantity of blood from the system generally may occasion the death of some of the extreme parts of the body, in which the circulation is naturally most languid. Thus Sir B. Brodie relates the case of a drunken man, who, being bled to an inordinate extent, was seized with gangrene of both feet. The want of a due supply of arterial blood to the limb may be occasioned in three ways :—1st, by the ligature or wound of the main trunk; 2d, by obstruct- ive arteritis; 3d, by calcification, and consequent occlusion of the vessel. This form of gangrene varies materially, according as it arises from one or other of these causes. When a limb becomes gangrenous in consequence of the ligature or wound of its main artery, without any other injury to the vascular system, it will be found to become cold, to feel heavy, and to lose its sensibility; at the same time it assumes a dull tallowy-white color, mottled with greyish or brownish streaks. This state of things is chiefly met with in the lower extremity; the integuments of the foot die, become semi-transparent and horny-looking where they are stretched over the tendons of the intsep, and the part thus presents a shrivelled appearance. In the course of a short time, the pallid color will be lost, the part becoming brown or blackish. This form of gangrene may invade the whole of the lower limb, but most commonly is limited to the foot, stopping either just above the ankle, or if not, then immediately below the knee, as Guthrie has observed; the arrest taking place in one or other of these two spota on account of the greater freedom of the collateral circulation here than in other parts of the limb. If any of the large venous trunks become obstructed or otherwise implicated, so that the return of blood through them is interfered with, at the same time that the supply by the arteries is arrested, the limb SPONTANEOUS AND SENILE GANGRENE. 355 Fig. 139. generally assumes a greenish-blue color, and rapidly runs into putrefaction. In some of these cases it happens that sloughs of the integument and subcutaneous cellular tissue form, although the limb generally preserves its vitality. The treatment of these forms of gangrene, which are strictly local, is described in the chapter (p. 174) on wounded arteries. Gangrene may occur from the circulation being arrested by disease taking place in the coats of the arteries. This is the variety of the affection, that is commonly called spontaneous. It may be the result either of obstructive arteritis, or of plugging up an artery that has undergone calcification or senile degeneration. Spontaneous gangrene from acute obstructive arteritis may occur at all ages; in young people as well as in old. It happens as frequently, indeed I believe more frequently, in the upper than the lower extremities, and is of the humid variety. Its pathology and treatment will be fully con- sidered when we come to speak of arteritis. Spontaneous gangrene is termed "senile" when it occurs in consequence of the coats of the arteries becoming rigid and calcified (fig. 139), and unable to maintain the circula- tion of the limb. It is met with in the lower extremities of people past the middle period of life, and increases as age advances : a sensation of weight in the limb occurs, with coldness, itching, and tingling in the feet, and with cramps in the calves, and the circulation of the part is habitually defective. This condition commonly exists for a conside- rable length of time'before gangrene comes on. In many instances this sets in without any exciting ciuse; but in other cases the mortification is immediately set up as the result of some slight inflammation accidentally induced; by the excoriation produced, perhaps, by a tight boot, or by a trivial wound in cutting a corn ; the inflammation occasioned by this slight injury being sufficient to disturb the balance of the circulation in the already weakened part to so great an extent, that gangrene ensues. This generally makes its appearance in the form of a cold, purple or blackish-red spot on the side of one of the toes; this spot may be sur- rounded by an inflamed areola, and accompanied by much smarting and burning pain; it spreads by gradually involv- ing the inflamed areola, which continues to extend in proportion as the gangrene progresses. In such cases the toes and feet simply shrivel, with- out any sign of local inflammation or con- stitutional disturb- ance. In one or other of these ways the * affection gra- dually creeps up the limb, invading per- haps one toe after _- the other, involving lis the instep and the sole of the foot, and, unless it terminate by the formation of the line of demarcation, or death put an end to the patient's sufferings, it may extend up the ankle or leg. The part that is affected is always black, dry, and shrivelled, resembling closely the Fig. 140. Femoral and tibial arteries obstructed in senile gangrene. 356 MORTIFICATION, OR GANGRENE. appearance presented by a dried mummy; hence it is often termed mummifi- cation (fig. 140). There is usually considerable constitutional disturbance sometimes pyrexial at first, but secondarily sinking into an irritative or as- thenic form, in these cases, and the disease is generally fatal in from a month to six weeks. I have known the disease continue, however, with very little constitutional disturbance for more than twelve months. In other instances, again, the gangrene being limited to a small extent, the patient may recover. Gangrene may also occur from inflammation affecting the principal artery of a limb, and perhaps occluding it completely, without any previous disease in the vessel. In these cases there are the usual signs of arteritis, such as ten- derness along the course of the vessel, cessation of pulsation in its terminal branches, intense superficial pain in the limb, followed by the rapid superven- tion of dark, dry gangrene in the whole of the extremity up to the point at which the vessel is inflamed. This affection, of extremely rare occurrence, has been described as spontaneous gangrene. In some cases it partakes of the cha- racters of the humid form, owing to the implication of the veins. It is, I believe, most frequently met with in the upper extremities, at least all the instances that I have seen of it have been situated there, and I have observed it most commonly in women, occurring even at an early period of life. It is of the dry variety, in consequence of the arrest of the flow of blood into the limb, and usually occurs in a broken constitution, being frequently fatal by the supervention of typhoid symptoms before any attempt can be made by nature to separate the mortified part; after death, in these cases, the inflamed vessel will be found firmly plugged up by a dense coagulum, which completely arrests the circulation through it. The pathology of the arterial system in reference to these two forms of gangrene, will be more fully discussed in a subsequent chapter. 3d. Venous obstruction.—Gangrene may arise from obstruction to the return of blood through the veins of a part, the disease occurring from the circulation being arrested by the overloading of the capillaries with venous blood. Gan- grene is especially apt to take place, if the arterial supply is diminished, at the same time that the return of venous blood is interfered with; as when an artery and vein are compressed, or when the femoral vein is wounded accidentally at the time that the artery is ligatured. Gangrene from this cause is always of the moist kind, attended by great swelling from oedema, with discoloration and rapid putrefaction of the part. This gangrene, from venous obstruction, is also especially apt to occur in those cases in which the heart's action is weakened, or the flow of blood in the aorta lessened, at the same time that the force of the impulse in the arterial system is so lowered that the heart is unable to push the blood through the loaded vessels. Those cases of gangrene of the extremities that are occasion- ally met with from pure debility, as after fevers, often appear to originate in this way. The various forms of traumatic gangrene, whether arising from the severity of the injury, from the inflammation following it, from the depraved condition of the blood, from the irritation of extravasated fluids, or from the effects of burns, or of frost-bite, have already been considered when treating of these respective injuries; and the more specific forms of the affection we shall shortly describe. Treatment. — As gangrene proceeds from such a great variety of causes, it must be very evident that no one plan of treatment can be applicable to this condition, and it becomes necessary, not only to modify our therapeutic means according to the cause of the disease, but also with special reference to the constitution of the patient, and with regard to the stage in which we meet with the gangrene; and, indeed, it often requires great tact and experience to accommodate the treatment in this way to the varying phases of the case. I TREATMENT OF SPONTANEOUS AND SENILE GANGRENE. 357 have already considered the treatment of the inflammatory (p. 104) and the traumatic and local (p. 175) forms of gangrene, and shall, therefore, consider merely in this place the general principles that guide us in the management of those varieties that have been considered as the result of constitutional causes — the spontaneous forms; and in these cases the constitutional management of the patient is of greater moment than the local treatment of the disease. In the constitutional treatment of these forms of gangrene, there are three principal indications: lstly. To remove the cause, if possible, and thus to arrest the gangrene. 2ndly. To support the powers of the system during the process of the separation of the sloughs; and 3rdly. To lessen the irritability of the nervous system. In the removal of the constitutional cause, we must look wholly to the con- dition of the patient's system; if this be in an inflammatory or. febrile state, we must have recourse to the modified antiphlogistic plan described at p. 86. But the opposite condition, that of debility, may equally occasion or complicate the gangrene, which may recognize an enfeebled state of the circulation of the part, or of the system generally, as its cause, and there may be every possible combination between this and the inflammatory condition. Under these circum- stances, it will be necessary to conjoin an antiphlogistic plan of treatment with remedies of a tonic, or even stimulating character. It is this plan of treatment that is commonly found to succeed best in the spontaneous gangrenes; here moderate antiphlogistics are perhaps required in the earlier stages, with a light nutritious diet and mild tonics as the disease advances, and in the later periods, when the constitutional symptoms assume an asthenic character, stimulants should be given. The best stimulants to administer in these cases are wine or porter, according to the patient's habits of life, and these should be given in combination with nourishment, so as not merely to raise the pulse, but to pro- duce a more permanent tonic influence on the system generally. If much depression occur, the medicinal stimulants, more especially ether, ammonia, and camphor, are of material service. The only tonics that are of much value in these cases, are the preparations of bark and some of the vegetable bitters, as gentian and cascarilla; and though the specific virtues that were formerly attributed to them can no longer be accorded, yet, when they do not irritate the stomach, they are of unquestionable service in combating the asthenic symptoms and improving the digestive powers. In these cases I look upon bark or gentian, in combination with the chlorate of potass and ammonia, as of undoubted value. After the proper employment of means calculated to remove the constitutional cause of the gangrene, the system must be supported against the debilitating effects that accompany the process of ulceration and of suppuration necessary for the separation of the mortified parts. During this period, there is less irri- tation and more debility, and stronger tonics and stimulants can be borne, but we should be careful not to overstimulate the patient. On this point it is ex- tremely difficult to lay down any rule; every possible variety as to the quantity and quality of food and stimulus being required by different individuals. The safest guides are the state of the pulse and tongue; if they improve, the means employed agree. At the same time hygienic measures should be carefully attended to; cleanliness and free ventilation, with the abundant use of the chlorides, are of the first moment, so that the patient be not poisoned by his own exhalations. The third indication, that of lessening the irritability of the system that always supervenes, and which is partly owing to the severity of the pain, and partly to the shaken and depressed state of the nervous system, is best carried out by the administration of opium; and although this drug may not act as a specific, as Pott supposed, yet in many cases, but especially in the gangrene of the toes and feet of old people, it is undoubtedly a remedy of the greatest value. A grain of the solid opium may be administered advantageously every 6th, 8th, 358 MORTIFICATION, OR GANGRENE. or 12th hour, according to the effect it is found to produce, care being taken at the same time that the bowels do not become confined. The hiccup, which is often distressing in these cases, is best remedied by the administration of chloric ether and camphor. The local treatment of the gangrenous part should be conducted on the prin- ciples described (p. 104), leaving the separation of the sloughs as much as pos- sible to nature, diminishing the feetor which occurs, by the use of the chlorides, preventing the absorption of morbid matters by the line of separation, and dressing this with wet lint or calamine cerate, and lastly, endeavoring to heal the ulcer that results on the detachment of the sloughs. The treatment of " senile gangrene," presenting, as it does, some peculiarities, requires a few words to be specially devoted to it. By some surgeons this dis- ease has been treated on a strictly antiphlogistic plan, on the supposition that the obstruction of the arteries was caused by the inflammation of their coats; this, however, is certainly an erroneous doctrine in a great number of cases; and though inflammation may occasionally affect the calcified coats of an artery, it is always a low form of the disease that does not bear depletion. Sir B. Brodie very justly observes, that in these cases the local precursory inflammation termi- nates in mortification, because the inflamed part cannot obtain the additional supply of blood that it requires; hence if blood is abstracted from the system, and the action of the heart weakened, the cause of the disease will only be aggravated. But though depletory measures are not admissible, we must guard against running into the opposite extreme, and over-stimulating patients labor- ing under this disease. Senile gangrene commonly occurs in individuals belonging to the wealthier classes of society, who have lived high, taken insuffi- cient exercise, and consequently got the system into an irritated, plethoric, but enfeebled state. In this condition stimulants and the more powerful tonics are not well borne, they heat the system, accelerate the pulse, and interfere with digestion; and, as Sir B. Brodie observes, it is of great importance in this dis- ease to attend to the state of the digestive organs, in order that nutrition may go on, and that blood of a proper quality may be made. In order to accomplish this, a light, nourishing diet, partly animal and partly vegetable, should be given, and a moderate quantity of wine, beer, or brandy allowed. The bowels must be relieved from time to time by a rhubarb draught or simple aperient pill. It is better to avoid mercury in any form in this disease, as it depresses the system, and hence it should not be used, even as an aperient, unless the state of the liver imperatively required it. If the digestion become impaired, a stomachic, as the infusion of cascarilla, or the compound infusion of gentian with a little ammonia, may be administered. The administration of opium in these cases, as recommended by Mr. Pott, has received the sanction of almost every practical surgeon. Sir B. Brodie's opinion on this point is peculiarly valuable; he says, " If I am not greatly mistaken, the result of a particular case will very much depend on this, — whether opium does or does not agree with the patient. From 2 to 4 grains of opium may be administered in divided doses in the course of the twenty-four hours, the quantity being increased as the system becomes accustomed to its effects. If it disturb the stomach and occasion headache not- withstanding the use of aperients, it must, however, be discontinued, as it will increase the irritation of the system. With respect to the comparative advan- tages of the depletory and stimulating plans of treatment in senile gangrene, I think it may fairly be stated that neither method should be employed exclusively; that in those cases in which there is much action going on, in which the spread of the gangrene is preceded by a red angry blush, with much pain and heat, low diet and moderate depletory measures will be most useful, whilst on the other hand when it is simply a shrivelling of the toes and feet, without any sign of being preceded by local increased action, or by constitutional disturbance of a febrile type, a tonic <»r stimulating plan will succeed best. TREATMENT OF SENILE GANGRENE. 359 The local means to be employed in senile gangrene are of a simple character. It is of great importance to keep up the temperature of the limb, and to equalize its circulation as much as possible; this is best done by the application of cot- ton-wadding or of carded wool, in thick layers around the foot and leg, so as to envelop the limb completely in this material, over which a large worsted stock- ing may be drawn, or a silk handkerchief stitched. This dressing need not be removed more than once or twice a week unless there is much discharge from the line of separation, then it must be changed more frequently; the gangrened part itself should be covered with a piece of lint, soaked in chlorinated lotions. When the soft parts have been separated, and the bones of the foot exposed, these should be cut across by means of cutting-pliers or a small saw, and the sore that results dressed in the ordinary way with some astringent lotion or slightly stimulating ointment. The Balsam of Peru, either pure or diluted with an equal part of yelk of egg, is a very excellent application in these cases. In the event of the patient recovering, he must be careful to avoid exposure to cold, and to keep the legs warmly clad at all seasons of the year. The question of amputation in cases of gangrene of the limbs is of great im- portance to the practical surgeon, and is one, on certain points of which the opinions of the best practitioners are still at variance. At first sight it appears rational to cut off a limb that is dead, disorganized, and offensive, and this may be done when the gangrene is, strictly speaking, a local condition; as, for in- stance, the result of a severe injury; any affection of the constitution in such a case as this being secondary to the local mischief, and dependent on the irrita- tion set up by it, and on the effort made by nature to rid the system of a spoiled member. But when the constitutional disease is the primary affection, and when the gangrene is consecutive to and dependent upon this, it would clearly be useless to cut off the mortified part, as the same morbid action might, and would, be set up in the stump or elsewhere. Hence the broad question of ampu- tation in cases of gangrene turns upon the fact of the mortification being local or constitutional in its origin. When the gangrene is local, therefore, we usually amputate at once. This is especially the case when the mortification results from severe injuries, or is the result of the wound or ligature of an artery. Here, I think, for the reasons that have been given (p. 176), that amputation should be performed as soon as the gan- grene has unequivocally manifested itself, without waiting for the line of demarc- ation. The result of amputation for traumatic gangrene is, on the whole, very unfavorable, the patient very commonly sinking from a recurrence of the disease in the stump, or from the constitutional disturbance that had previously set in; those cases being especially unfavorable in which the cellular tissue of the limb is much infiltrated and disorganized, the affection indeed partaking more of the characters of constitutional disease, with some forms of which it is closely asso- ciated. There are two exceptions to the rule of amputating in traumatic and local gangrene before the occurrence of the line of demarcation, viz., in the case of gangrene from frost-bite, and in that from severe burns; in these injuries it is better to wait for the line of separation to form, and then to fashion the stump through it as the circumstances of the case require. In gangrene from constitutional causes, it is a golden rule in surgery never to amputate until the line of separation has formed; for as it is impossible in these cases to say where the mortification will stop, the amputation might be done either too high, or not high enough; and, under any circumstances, the morbid action would to a certainty be set up in the stump. It is not even sufficient in such cases as these to wait until the line of demarcation has formed before removing the limb; these spontaneous or constitutional gangrenes having often a tendency to remain stationary for some days, and then creeping on, may readily overstep the line by which they had at first appeared to be arrested. Besides 360 GANGRENOUS DISEASES. this, the local disturbance and inflammation set up by the amputation might be too great for the lessened vitality of the system or part, and might of itself occa- sion a recurrence of the gangrene. Hence in these cases it is always well to wait until the line of separation has ulcerated so deeply that there is no chance of the gangrene overleaping this barrier, at the same time that means are taken, by the administration of tonics, nourishing food, &c, to improve the patient's strength and fitness for the operation. So soon as this has been done in a satis- factory manner, and all the soft parts, except the ligaments, have been ulcerated through, the mortified part should be separated, by cutting through the remain- in "■ osseous, ligamentous, or tendinous structures, and then means should be taken to fashion the stump that has been so formed by nature. In some cases this will be sufficiently regular to serve every useful purpose after it has cica- trized ; in most instances, however, it will be found that the bones protrude to such an extent, or that the ulceration has affected the soft parts so irregularly, that it will be necessary, in order to give the patient a useful limb, to amputate through the face of the stump, or higher up; all this, however, must be left to the discretion of the surgeon, but no procedures of this kind should be under- taken until the patient's strength has been restored sufficiently to bear the operation. In senile gangrene it has recently been proposed to amputate the thigh high up. This practice has been successfully adopted by Mr. Garlike, Mr. James of Exeter, and others, and certainly deserves a trial in all cases in which the health is otherwise good and the constitution tolerably sound. It has not as yet been adopted in a sufficient number of cases to warrant a positive opinion on its merits; but it would appear that for it to succeed, the amputation should be done high up in the thigh, so that there may be a better chance of meeting with a healthy condition of the vessels and good vitality in the limb; the opera- tion being performed on the principle, that this form of gangrene is dependent on local disease obstructing the vessels of the part, and not always on constitu- tional causes. CHAPTER XXVI. GANGRENOUS DISEASES. BED SORES. When a part of the body is compressed too severely, or for too long a time, even in a healthy constitution, it loses its vitality, and a local limited slough results; this separates, and an ulcer is left, which cicatrizes in the usual way. But in certain deranged states of the health, more especially when the blood is vitiated and the constitutional powers lowered, as during fever, or when the patient is old, debilitated, or paralyzed, the skin covering those points of the body that are pressed upon in the recumbent position, such as the sacrum, the trochanter, the elbows, shoulders, and heels, becomes congested and inflamed, assuming a dull reddish-brown color, and speedily becomes excoriated without any pain being felt by the patient. If means be not taken to relieve the part from the injurious compression to which it is subjected, and more especially if it be irritated by the contact of faeces or urine, the subcutaneous cellular tissue corresponding to the inflamed patch will be found to have become widely softened and doughy, being converted, with the skin covering it, into a tough SLOUGHING PHAGEDENA. 361 greyish slough, from under which a thin ichorous pus exudes. This slough may extend by a process of undermining of the integuments covering it, and on its separation extensive mischief will be disclosed, the fascia and tendons being exposed, or the bones laid bare, and soon becoming roughened and carious. In some cases, even, the inferior aperture of the spinal canal may be laid open, or death result from a low form of arachnitis, in consequence of the irritation spreading to the membranes of the cord. In other cases, again, the patient dies worn out by discharge and irritation. The treatment of these cases is in a great measure of a preventive character. When a patient is likely to be confined to bed for many weeks, especially by an exhausting disease, steps should be taken, by proper arrangement of the pillows, and by the use of the water-bed and cushions, to prevent pressure being injuriously exercised upon any one part. At the same time cleanliness and dryness should be carefully attended to, by proper nursing, by the use of a draw-sheet, and by furnishing the bedstead with the necessary arrangements of bed-pan, etc. The skin on the exposed parts may be protected by the appli- cation of collodion or soap-plaster spread upon wash-leather or amadou, or, what is better, may be strengthened by being washed with spirits of wine, either pure, or having two grains of the bichloride of mercury dissolved in each ounce. If the skin have become chafed, the removal of pressure is imperative, and the abrasion may be washed over with collodion; if a sore has formed, it may be dressed with the balsam of Peru, either pure or diluted with the yelk of egg, spread upon lint. In these cases, also, the use of the prone couch may occasionally be advantageously substituted for that of the ordinary bed pre- viously employed. When sloughs have formed, their separation must be facilitated by the use of charcoal or chlorinated poultices, and the ulcers that are left should be dressed with astringent and aromatic applications, such as catechu, tincture of myrrh, etc.; but no dressing that the surgeon can apply will cause these ulcers to heal, unless the patient's general health improve, and then they will speedily get well under simple treatment. SLOUGHING PHAGEDENA. This affection, which is also commonly known by the names of hospital, con- tagious, or pulpy gangrene, is a disease characterized by a rapidly destructive and spreading ulcer, covering itself as it extends by an adherent slough, and attacking open sores and wounds. It is rarely met with in its fullest extent, except in military practice; the accumulation of the wounded, and the want of the necessary cleanliness and attention during an active campaign, appearing to dispose to it. It used formerly to desolate the civil hospitals, but, thanks to the sanitary measures that are now so generally adopted in these institutions, it has almost disappeared from them, though still an outbreak of it occasionally takes place. During the last few years, it has been met with in most of the London hospitals, and has twice made its appearance in that of the University College. When sloughing phagedaena invades a wound that is previously perfectly healthy, the surface of the sore becomes covered with grey, soft points of slough, which rapidly extend, until the whole of the ulcer is affected. At the Bame time it increases rapidly in superficial extent, and commonly in depth; the surrounding integument becomes cedematous, swollen, and of a livid red color; the edges of the ulcer are everted, sharp cut, and assume a circular outline, and its surface is covered with a thick, pulpy, greyish-green tenacious mass, which is so firmly adherent to the sore that it cannot be wiped off from it, being merely moved or swayed to and fro when an attempt is made to clean it. There is usually some dirty yellowish-green or brownish discharge, 362 GANGRENOUS DISEASES. and occasionally some bleeding; the pain is of a severe burning, stinging, and lancinating character, and the fcetor from the surface is considerable. The ravages of this disease, when fully developed, are very extensive. The soft parts, such as the muscles, cellular tissue, and vessels, are transformed into a grey pulpy mass, and the bones are denuded and necrosed. The larger blood- vessels resist the progress of the disease longer than any other parts, but may at last be exposed, pulsating at the bottom of the deep and foul chasm. There is little risk of hemorrhage taking place, however, in the early stages; but when the sloughs are separating, an artery may give way, and bleeding to a dangerous or fatal extent ensue. Hennen states that there is most danger of this happening about the eleventh day. When the sloughs are thrown off, in the form of reddish-brown or greyish-green viscid and pulpy masses, a very sensitive granulating surface is left, having a great tendency to bleed, and to be again invaded by the sloughing action. Blackadder has described an ulcerated form of this affection, in which a vesicle containing a bloody ichor forms, with a hot, stinging pain; this breaks, leaving a circular ulceration about the size of a split pea. The ulceration once formed, rapidly extends by sharp-cut edges into the surrounding integument. On the two occasions that I have had the opportunity of witnessing out- breaks of this disease, in the University College Hospital, the surface of the wound affected became rapidly covered with a yellowish-grey pultaceous slough. In some cases there was hemorrhage, but most commonly a small quantity of fetid discharge only was poured out, the edges of the sore became sharp-cut and defined, and the ulceration extended further in the skin by an eighth or a quarter of an inch than in the subjacent cellular tissue. In the majority of instances, the disease was confined to the skin and cellular tissue, exposing, but not usually invading, the muscles and bones, though in some cases these were affected. The ulcers, which had a somewhat circular shape, were surrounded by a dusky inflamed areola of some width. When once the morbid action was stopped, they cleaned rapidly, throwing out large vascular granulations. The constitutional symptoms are inflammatory in the first instance, with a tendency to asthenic and irritative fever as the disease advances. In the majority of cases they follow the local invasion of the sore; Blackadder, Rollo, Delpech, and Wellbank, have all found this to be the case, and in the instances at University College Hospital it certainly was so. Hennen and Thompson, on the other hand, state that the constitutional symptoms precede the local ones. This discrepancy of observation may be explained by the difference in the cause of the disease; if it occur from contagion, the constitutional symptoms will be secondary; if from causes acting on the general system, they may probably be primary, to the local affection. All wounds and sores are liable to be attacked in this way, but the disease most frequently affects those that are of recent origin; the more chronic affections, and those that are specific, very usually escape. The causes are of various kinds; primarily it commonly originates from overcrowding in hospitals, from want of cleanliness, ventilation, and change of dressings; from that accumulation, indeed, of animal exhalations arising from the sick and wounded, which is a source of various forms of low fever and of allied diseases; and when so occurring, this disease may be taken as an evidence of the infringement of the sanitary laws in accordance with which the arrangements of the institutions should be regulated. But though it commonly has its origin in this way, especially in the crowding of military hospitals after a hard-fought action, it is met with out of hospitals. Well-marked cases of this affection, some of a very severe character, have at times occurred amongst the out-patients at the University College Hospital. In these cases, as in many others, it was probable that the disease was occasioned by the neglect of hygienic conditions in the close and ill-ventilated houses of the poor aided SLOUGHING PHAGEDENA. 363 possibly by some atmospheric or epidemic influence; influenza, erysipelas, and phlebitis being also very prevalent. This had been observed at the time of the first occurrence of the disease at our hospital, in 1841, and I think it is difficult not to recognize a similarity of cause in these different affections. When once it has occurred it may rapidly spread by contagion, though there is no evidence to show that it is of an infectious character. Hence the necessity of preventing its being spread by nurses or attendants, by the incautious use of sponges, and of destroying the dressings used by the patients. In the treatment of this affection the first point to attend to is to prevent the extension of the disease to patients that are not as yet affected by it. This may be done by separating those that have been seized with it, from the healthy, by ventilating the wards, washing the floors with a solution of the chlorides, whitening the walls, and fumigating the apartment with chlorine gas. The extension of the sore must be stopped by the free application of fuming nitric acid, or of the actual cautery to its edges and surface. I have used both these agents, but give the preference to the nitric acid if strong and freely applied, the sides and edges being well sponged with it. The actual cautery is, however, very useful in those cases in which the surface to be destroyed is very extensive, or if there is a tendency to hemorrhage. Should it not reach the deeper portions of the sore, nitric acid may be freely sponged into them. After the cauterization a strip of lint soaked in a strong solution of the watery extract of opium, should be laid around the margin of the ulcer, so as to cover the surrounding areola; and the separation of the sloughs must be encouraged by the continued application of charcoal, yeast, or chlorinated poultices. When they have separated, and the surface of the sore has cleaned, it may be dressed with a lotion composed of one grain of the sulphate of copper, and five of the watery extract of opium to the ounce of water. The granulations, which are very luxuriant and vascular, will be found to skin over with great rapidity, and the cicatrix like that of an ordinary burn will contract very firmly. Should arterial hemorrhage occur, it must be arrested by the application of a ligature to the bleeding point, but if this does not hold, as will probably be the case from the softened state of the tissues, the actual cautery must be applied, or, the limb at last removed in the event of all other means failing. In some cases it happens that though the sloughing action is checked at one part of the surface, it has a tendency to spread at another. When this is the case it may be necessary to apply the caustic or cautery repeatedly. In others again, the sloughing action cannot be stopped, but opens large arteries, and destroys the greater part of the soft tissues of a limb, and then it may be a question whether amputation should be performed during the spread of the disease, or the patient left to die of hemorrhage or exhaustion. Such a contin- gency is not of common occurrence, but yet it may happen, and the operation be successful, as appears by the following case, though there would necessarily be great danger from a recurrence of the disease in the stump. The wife of a butcher applied at the hospital, with a slight wound of the forearm, inflicted by a hook. It was dressed in the ordinary way, but in the course of a few days she returned with extensive sloughing phagedaena of the part, she was immediately admitted, and the disease was arrested by the energetic employment of the local treatment above described; not, however, until after considerable destruction of the tissues on the inside of the forearm had taken place. She left the hospital before the wound was completely cicatrized, and returned in a few days with a fresh attack of the disease more extensive and severe than the first, and which could not be permanently stopped, either by the actual cautery or nitric acid. The radial artery was opened and required ligature, and the whole of the soft parts, from the wrist to the elbow, were totally disorganized, and the bones exposed. There was now very severe constitutional irritition, and the case was evidently fast hastening to a fatal termination. Under these 364 GANGRENOUS DISEASES. circumstances I amputated the arm midway between the shoulder and elbow; and, notwithstanding that the local disease was progressing at the time of the operation, and the great constitutional disturbance that existed, the patient having a pulse of 160 to 170, at which it continued for more than a fortnight, she made a good recovery; to which the free administration of stimulants greatly contributed. The constitutional treatment of this disease must have for its object the removal of the combined state of debility and irritation in which we find the patient. The bowels should be kept freely opened by warm aperients; as nourishing a diet as the patient will take, with a liberal supply of stimulants, should be ordered, and these may be increased by the addition of the brandy- and-egg mixture, or of ammonia in proportion as depression comes on. At the same time I have found great advantage from the administration of a mixture of carbonate of ammonia, gr. v.; chlorate of potass, Bj ; compound tincture of bark, 3 j ; decoction of bark, % jss, every four or six hours; or if the patient will bear it, quinine in full doses, from five to seven grains of the sulphate every six hours, with an opiate at bed-time, or more frequently if there be much pain and irritation. GANGRENOUS STOMATITIS, OR CANCRUM ORIS. A peculiar phagedsenic ulceration, closely resembling the last-described affec- tion, is occasionally met with in the mouths of ill-fed children living in low and damp situations, most commonly occurring between the second and sixth or eighth years, but more especially about the period of the second dentition. The mildest form of this affection presents itself as small, deep, and foul greyish ulcers, situated on the inside of the lips or cheeks, and attended with a red spongy condition of the gums and much fcetor of the breath. In these cases, good food and air, with nourishing diet, the administration of bark, with the chlorate of potass, and the use of chlorinated lotions, with the honey of borax, will soon bring about a cure. The Spanish snuff (Sabilla) applied to the sore mouth, or placed in a small cambric bag on the tongue, has a very good effect in cleansing these sores, and especially in soothing irritation. In the more severe form of the affection, the true cancrum oris, we find, commonly during convalescence from some of the eruptive diseases of child- hood, or, if mercury have been incautiously administered during a weak state of the system, that one of the cheeks becomes swollen, brawny, tense, and shining, being excessively hard, and presenting a red patch in its centre. In consequence of this swelling, it is -often difficult to open the mouth; but if the surgeon can gain a view of its inside, he will see a deep and excavated foul ulcer opposite to the centre of the external swelling, covered with a brown pulpy slough. The gums are turgid, dark, and ulcerated, the saliva is mixed with putrescent matters, and as the ulceration in the mouth extends, the swell- ing sloughs, and a large, dark, circular gangrenous cavity forms in the cheek, opening through into the mouth; during all this time the child suffers little, but, as the disease advances, it commonly becomes drowsy, and at last dies comatose. When fully developed, this affection is most fatal. Rilliet and Barthez state that not more than 1 in 20 cases recovers. The treatment of cancrum oris is that of hospital gangrene; the sloughing mass should be deeply cauterized with nitric acid, but not with the actual cau- tery, lest the cheek be destroyed, the mouth syringed with the dilute chlorides, and the system supported with beef-tea, wine, and ammonia, in doses propor- tioned to the age of the child. After the cure of the disease, the cheek may be deeply cicatrized, contracted, and rigid, much in the same way as after a burn, requiring possibly some plastic operation in order to enable the child to open its mouth properly. BOILS — CARBUNCLE. 365 BOILS. A boil is a hard circumscribed tumor of a violet or purplish-red color, flat- tened, though somewhat conical, suppurating slowly and imperfectly, and always attended by a small conical central slough of cellular tissue called a core. It consists of an inflammation of the subcutaneous cellular tissue, and of the under surface of the true skin. The tension and hardness accompanying this affection render it extremely painful and annoying to the patient. It is most commonly seated in the thick skin of the back, the neck, or the nates. Boils most frequently make their appearance in young people, but are com- mon enough at all ages, and are usually seen either in very plethoric or in very enfeebled constitutions, often following some of the more severe febrile dis- eases, and attending convalescence from them. In other cases, the system ap- pears to have fallen into a cachectic state, often without any evident cause, and this terminates by a critical eruption of boils. A sudden change in the habits of life, as from sedentary to active pursuits, a course of sea bathing, &c, will also occasion them. They are commonly met with in the spring of the year, but may occur at all seasons, and are occasionally epidemic, as has been the case during the last few years in London. When once they take place, they are often extremely tedious, crop after crop continuing to be evolved. In the treatment of boils, the constitutional condition of the patient, on which the disease is dependent, requires to be carefully attended to. As they most commonly occur in a cachectic and broken state of the system, the pre- parations of iron will be found to act beneficially. This mineral may very advantageously be administered in combination with ammonia and chlorate of potass, after which the patient may be put upon a course of sarsaparilla or bark with the mineral acids. Should this fail, and the boils appear to be dependent on a low state of health, quinine in large doses, in combination with sulphuric acid, may be advantageously used. In other instances again, and especially if the disease be associated with pompholyx, arsenic will be found of service. In many cases, however, the surgeon will be baffled whatever be the treatment he adopts, the tendency to the disease appearing rather to terminate of itself, than brought to a close by remedial measures. During this plan of treatment, it is necessary to keep the bowels free by the occasional administration of an aloetic purgative. If the boils occur in young people who are otherwise tolerably healthy, or in plethoric individuals, this tonic plan of treatment will not suc- ceed ; but saline aperients and the liquor potassae, in doses of from twenty to thirty minims twice a day, will usually speedily remove the affection. In some cases yeast may be advantageously administered. The local treatment of this disease is of a simple character; when they are forming, the most useful dressing is a warm spirit lotion kept.applied with lint and oiled silk; as suppuration comes on, a linseed meal poultice, either simple or made with port wine, may be advantageously applied. Most commonly the boils may be allowed to break, when they discharge a thick pus, together with the central core, thus leaving a small cavity in and under the skin, which, however, soon fills up. The surgeon may in some cases find it necessary to open them with a crucial incision if they are large, and do not appear disposed to break of themselves. When the boils commence as a small irritable pustule, they may occasionally be kept back by touching the point of this with nitrate of silver, or a saturated solution of the bichloride of mercury. CARBUNCLE. A carbuncle consists essentially of a circumscribed and limited inflammation of the subcutaneous cellular tissue, rapidly running into suppuration and slough. Indeed, the formation of pulpy greyish or ash-colored sloughs, whether re- 366 ERYSIPELAS. suiting from the specific nature of the inflammation, or from the strangulation of the parts by the accumulation of serum and blood, is characteristic of the disease. A carbuncle begins as a flat, painful, hard, but somewhat doughy, circum- scribed swelling of the integuments and subjacent cellular tissue. It is of a dusky red hue, slightly elevated, but never losing its flattened circular shape • ss it increases in size, the skin covering it assumes a purple or brownish-red tint, becomes undermined, and gives way at several points, forming openings through which ash-grey or straw-colored sloughs appear, and from which an unhealthy purulent discharge scantily issues. The size of these swellings varies from one to six inches in diameter; most commonly they are about a couple of inches across. Carbuncles are generally met with on the posterior part of the trunk or neck, being rarely seen anteriorly, or on the extremities. I have, however, had to treat a very large carbuncle situated on the abdomen, and have met with them on the shin, forearm, forehead, and often on the face. The constitutional disturbance attending this disease is always of the asthenic type the complexion is peculiarly sallow or yellow, the pulse feeble, and tomnie loaded; and if the tumor be large, or is seated on the head, a fatal termination may take place, the patient sinking into a typhoid state. This affection, with many points of resemblance, yet differs from boils in its greater size, the dusky red of the inflamed integument, its broad flat character, and the large quantity of contained slough in proportion to the small amount of purulent discharge. Unlike boils, carbuncle is very rare in young people, and never occurs in robust individuals. Indeed, it is always occasioned by, and is by itself indicative of a broken state of the constitution, being usually met with in individuals of a debilitated and irritable habit of body who have passed the middle period of life. The treatment of carbuncle consists in supporting the constitutional powers by the use of the preparations of bark in combination with ammonia, dietetic stimulants, and such nourishment as the patient will take, care being had at the same time to clear out the bowels well, as the intestinal canal in these cases will often be found to be offensively loaded. The local treatment consists in making an early and free crucial incision through the whole thickness and extent of the swelling. If the sloughs that are now exposed be loosened, they must be removed, and if not completely detached, the part must be covered with linseed and port wine poultices, and when the sloughs have cleaned off, the sore that is left should be dressed with Balsam of Peru, creasote, or the unguent Elemi. There are two other gangrenous diseases, the malignant pustule, and a pecu- liar dry gangrene of the extremities, induced by eating spurred rye, and hence called\ ergotism. These affections, however, are so rarely met with in this coun- try, that their consideration need not detain us. CHAPTER XXVII, . ERYSIPELAS. Erysipelas is an affection that so frequently and seriously complicates most other surgical diseases and injuries, that its study is- of the utmost importance to the practical surgeon. It usually manifests itself as a peculiar and distinct form of inflammation; as much so as any of the other varieties, the adhesive, ERYSIPELAS. 367 the suppurative, the ulcerative or the gangrenous. Erysipelas, or, as it may be termed, the erysipeloid infiammation, including all those varieties of this condition that are usually spoken of as " diffuse," has a remarkable tendency to spread or diffuse itself with great rapidity by continuity of surface, to change its seat, and not to be limited by any adhesive action. It may extend itself over any continuous surface; the skin, the cellular tissue, the mucous and serous membranes, and the lining membrane of arteries, veins, and lymphatics, are all liable to be affected by it. Hence, to describe it as a cutaneous disease, as has often been done, is in the highest degree incorrect and unphilosophical, and evinces a very limited acquaintance with its true nature. Indeed, not only must we look upon erysipelas as a disease that may affect any surface, external or internal, but we must consider the constitutional disturbance that takes place in erysipelas as the essential disease. This, it is true, is usually complicated with diffuse inflammation of the integument, and then constitutes one of the ordinary forms of erysipelas. But a constitutional fever may occur of precisely the same type as that which we observe to precede and to accompany the local inflammation without any such complication. This I had especial occasion to observe in a very fatal outbreak of erysipelas that took place in one of my wards a few years ago. On that occasion, all the cases in which the cutaneous form of erysipelas appeared were marked by severe constitutional disturbance, attended by much gastro-intestinal irritation. But precisely the same type of general febrile symptoms, and the same irritation of the stomach and bowels, occurred in patients in the same ward, in whom no local or surface evolution of the disease took place, as in those affected by the ordinary cutaneous form of it. The true pathology of the diffuse, low, or erysipelatous inflammations has yet to be made out. They are all closely connected with one another, and are evidently blood or constitutional diseases, under whatever name they go. The similarity of causes, of effects, and of constitutional disturbance, makes it probable that they are all essentially dependent on one common condition of the blood, and that the particular local manifestation that occurs, whether it be erysipelas, phlebitis, low cellulitis, or diffuse abscess, is secondary to this, and perhaps in some degree accidental. A chief characteristic of this erysipeloid fever is its incompatibility with the localization of any inflammation that may exist at or occur after its invasion; and hence, when it attacks the system, it causes already existing inflammations to assume a diffuse or spreading character, extending themselves over any sur- face on which they happen to be situated. It is especially apt, in this way, to cause those inflammations to spread which have not already been localized, by the deposit of adhesive matter. Hence, recent wounds are more liable to be affected by it than granulating ones, in which the inflammation has already taken on a plastic character, which requires to be overcome before the diffuse form can set in. The constitutional fever in erysipelas almost invariably at first assumes the sthenic form, but very speedily runs into an asthenic or irritative type, with a quick feeble pulse, brown tongue, pungent hot skin, and muttering delirium. The disease is truly an affection of debility; it is in consequence of the want of a sufficient degree of power in the part, or in the system, for the deposit of plastic matter, and the limitation of the inflammation by this, that the local affection spreads itself unchecked along the surface it invades. The tendency that invariably exists in erysipelas to the occurrence of sloughing and suppu- ration of the affected tissues, is a further indication of the asthenic and low character of the disease. This view of the nature of the constitutional dis- turbance in erysipelas is of great importance in reference to the treatment of the disease, as it demonstrates the necessity of not lowering the patient's powers too much during the early period of the affection, when it often tempo- rarily assumes a truly sthenic character. 368 ERYSIPELAS. Erysipelas is especially apt to become complicated with low visceral inflam- mation ; the membranes of the brain, the bronchi and lungs, or the gastro- intestinal mucous surface, are commonly implicated in this way; and it is often through these complications that death results. Causes.—Erysipelas may arise from causes existing in the patient himself, or from the conditions by which he is surrounded or to which he is subjected. It commonly originates primarily in want of attention to the hygienic condi- tions that should surround a patient; and is one of the penalties inflicted by Nature on those who neglect or are incapable of attaining those prime requi- sites of health—good food, temperance, cleanliness, and pure air. Were these attended to as they should be, erysipelas and the allied diffuse inflammations would scarcely be met with. Some persons appear to be naturally predisposed to erysipelas to so great a degree, that the application of cold or slight stomach derangement, or a trivial superficial injury may excite it. This predisposition to erysipelas most commonly takes place in individuals of a plethoric and gross habit of body; those especially who have a tendency to gout appearing to be liable to the ready occurrence of the disease. But this predisposition is most generally acquired by habitual derangement of health, and is especially induced by any of the depressing causes of disease, such as over-fatigue, anxiety of mind, night watching, and habitual disregard of hygienic rules as to diet, exercise, air, &c. The habit of body, however, in which erysipelas is most frequently met with as a consequence of very trivial exciting causes, is that which is induced by the habitual use of stimulants to excess. It is more espe- cially in that state of the system characterized by an admixture, as it were, of irritability and of debility, in which no plastic lymph is deposited as the result of inflammation, but in which this condition is followed by a rapid tendency to the formation of pus and slough, and to extension of disease in a diffuse form, that erysipelas is so very readily induced. This condition of body is met with amongst the laboring poor as the result of the privation of the necessaries of life, conjoined with the habitual over-use of stimulants and exposure to the various depressing causes of diseases, arising from bad food, impure air, &c. Amongst the wealthier classes it occurs as a consequence of high living, want of exercise, and general indulgence in luxurious and enervating habits. Some diseased states of the blood appear to predispose, in the highest degree, to the supervention of erysipelas. This is especially the case in diabetes and in granular disease of the kidneys attended by albuminuria. As a consequence of renal disease, erysipelas will occur idiopathically, or from the most trivial causes; a scratch, the sting of an insect, or any of the minor operations in surgery, more especially about the lower part of the body, will occasion it. And not only is it readily induced in this way, but it will extend in an uncontrollable manner in these states of the system, there being apparently in them an utter want of limiting or reparative power in an inflammation however set up. Amongst the circumstances that surround the patient, and that tend to the production of this disease, season of the year and atmospheric changes exer- cise a marked influence. Not only is erysipelas much more frequent in the spring and autumn than at other seasons of the year, but we not unfrequently find it coming on suddenly on the setting-in of cold easterly winds, or on the occurrence of sudden atmospheric vicissitudes. So also erysipelas often assumes an epidemic character, as the result of those peculiar, but, at present, inexpli- cable conditions of the atmosphere, in which disease generally assumes a low type, and in which epidemic catarrhs, influenza, phlebitis, and other allied affections prevail. Epidemic erysipelas is almost invariably of a low form, and is very commonly associated with some peculiar train of visceral complication that distinguishes the particular outbreak of the disease. But not only is erysipelas epidemic, it is also contagious. The contagion of CAUSES AND SYMPTOMS OF ERYSIPELAS. 369 erysipelas, after having been repeatedly denied, can I think no longer be con- tested. Travers, Copland, Bright, Nunneley, and others have adduced cases in proof of its contagious character, and instances have repeatedly fallen under my own observation, in which erysipelas, often unfortunately of a fatal form, has been communicated to the servants, nurses, or relatives of patients affected by it. A remarkable proof of the contagious nature of erysipelas occurred in the spring of 1851, in one of my wards at the University College Hospital. The hospital had been free from any cases of the kind for a considerable time, when on the 15th of January, at about noon, a man was admitted under my care with gangrenous erysipelas of the legs, and placed in Brundrett Ward. On my visit, two hours after his admission, I ordered him to be removed to a separate room, and directed the chlorides to be freely used in the ward from which he had been taken. Notwithstanding these precautions, however, two days after this, a patient, from whom a necrosed portion of ilium had been removed, a few weeks previously, and who was lying in the adjoining bed to that in which the patient with the erysipelas had been temporarily placed, was seized with erysipelas, of which he speedily died. The disease then spread to almost every case in the ward, and proved fatal to several patients who had recently been operated upon. In several instances patients were affected with the constitutional symptoms without any appearance of local inflammatory action, but characterized by the same gastro-intestinal irritation that marked the other cases. Erysipelas may not only spread in this way from patient to patient, but any diffuse inflammation, as phlebitis, inflammation of the absorbents, low or puer- peral peritonitis and pyemia may give rise to external erysipelas,-and in its turn be occasioned by it—a strong argument in favor of the allied nature of all these affections. Then again the contact of dead or putrescent animal matters with recent wounds may occasion it. In this way the disease is not unfrequently originated in hospitals by dressers going direct from the dead house, and espe- cially from the examination of the bodies of those who have died of diffuse inflammation, to the bedside of patients without taking sufficient care to wash their hands or change their clothes. For this reason also it is of great conse- quence that the same instruments be not used for practising operations on the dead, and performing them on the living body. The principal exciting cause of erysipelas is certainly the presence of a wound. It is chiefly recent wounds, however, that are affected by it; when once the adhesive or suppurative inflammation is set up, the wound is not so liable to take it on unless it be in bad constitutions, the formation of limiting fibrine appearing to lessen the liability to the occurrence of the disease. When erysipelas is epidemic, it is well for the surgeon not to perform any operation that can conveniently be postponed until it is less rife; and in no case should a patient on whom an operation has recently been performed be put in a neigh- boring bed, or even in the same ward, as a case of erysipelas. The size of the wound has little influence on the occurrence of erysipelas, which takes place as readily from a small as from a large one. The more severe forms of erysipelas however, chiefly occur in those cases in which the fasciae of the limbs are opened up, when the disease may spread through the deeper intermuscular planes of cellular tissue. Injuries about the head and hands are those that are most liable to be followed by this disease. But though we must constantly bear in mind the constitutional nature of erysipelas, it will be more convenient and practical to describe it as it affects different tissues and organs. With this view, we may divide it primarily into external and internal erysipelas. By external erysipelas is meant that variety of the disease which affects the skin and subcutaneous cellular tissue. This form of the affection has been described with an absurd degree of minuteness so far as the transitory and 24 370 ERYSIPELAS. accidental characters of its duration, shape, and appearance are concerned, by many of the writers on the Diseases of the Skin, who, in their anxiety to record minute and accidental shades of difference in appearance, have entirely lost si«ht of the true nature of the disease. The division adopted by Lawrence into the simple, the (Edematous, and the phlegmonous forms, is a practical arrange- ment that is commonly adopted by surgeons. I prefer, however, and shall adopt the division made by Nunneley in his very excellent work on erysipelas, as founded on the true pathology of the affection. He arranges external erysipelas under the cutaneous, the ccllulo-cutaneous, and the cellular varieties. 1st. The cutaneous erysipelas is the slightest form of the disease, implicating merely the skin; it comprises many of the species of erythema of different writers, and corresponds to the simple erysipelas of Lawrence. The symptoms of this affection are as follows: — A patient is seized with rio-ors, alternate chills and flushes, followed by headache, nausea, a quick pulse, a coated tongue, and hot skin; in from twenty-four to forty-eight hours the rash appears, though sometimes it comes out simultaneously with the constitutional disturbance. If there be a wound, the secretions of this dry up, and the margins become slightly swollen, and affected by the red blush. If the disease occur idiopathically without a wound, it most commonly appears upon the face, next upon the legs, and lastly upon the trunk. The rash is of a uniform but vivid rosy red hue, sometimes becoming dusky, and always disappearing on pressure; it usually fuses away into the color of the healthy skin, but is some- times distinctly margined. It is accompanied by some slight cedematous swell- ing which is often considerable where the cellular tissue is loose, as in the eyelids and scrotum, and there is usually a stiff burning sensation in the part. Vesicles or blebs often form, containing a clear but hot serum, which speedily becomes turbid, and dries into brawny desquamation. The redness may spread rapidly along the limb or trunk, or if the face is affected, travel quickly from one side to the other, causing such swelling of the eyelids as to close them, and giving rise to much tensive pain in the ears. Sometimes the disease disappears in one part of the body, reappearing in another. This, which is the erratic erysipelas, is often a dangerous form of the affection, occurring in advanced stages of pyemia, and indicating approaching death. In these varieties of idiopathic erysipelas, Arnott states that the fauces are always involved. This affection usually disappears without inducing any serious mischief in the part affected, but in some cases abscesses form, more especially in the loose cellular tissue of the neck and of the eyelids. In other cases again, oedema of the part continues with some irritability and redness of the skin and peeling of the cuticle; and in some rare cases the simple erysipelas seems to take on a gan- grenous or sloughing character, especially about the umbilicus and genitals of young children. The constitutional symptoms of the cutaneous or simple erysipelas, present every variety between the sthenic and asthenic forms of inflammatory fever. When the disease occurs in London, it certainly most frequently assumes a low type. There is also in most cases a good deal of derangement of the digestive organs, the tongue being much coated, with tenderness about the epigastrium, dark offensive evacuations, and not unfrequently diarrhoea. When the scalp is affected, severe headache, with symptoms of cerebral inflammation, are commonly met with. Most frequently recovery takes place by the gradual subsidence of the symptoms; this form of the disease seldom proving fatal unless the scalp is affected, and the brain consequently implicated. 2nd. The cellulo-cutaneous or phlegmonous erysipelas differs from the variety just described, in the degree of inflammation, and the depth to which the tissues are affected. The intensity of this form of inflammation is such as invariably to terminate, if left to itself, in diffused suppuration and sloughing of the tissues. In depth it invariably extends to the subcutaneous cellular tissue, and VARIETIES AND SYMPTOMS OF ERYSIPELAS. 371 though generally bounded by the fasciae lying beneath this, not unfrequently implicates these if they have been opened up, extending to the inter-muscular cellular planes, the sheaths of the tendons, and other deep structures of the limb or part. The cellulo-cutaneous or phlegmonous erysipelas is ushered in by the ordinary symptoms of inflammatory fever, accompanied or followed by the signs of severe inflammation in the part affected. The redness is uniform, of a deep scarlet hue, and pretty distinctly bounded; the pain is from the first pungent and burning, though it may soon assume a throbbing character; the swelling, at first soft, diffused, and admitting of distinct pitting, soon increases, and becomes tense and brawny, the skin being evidently stretched to its full extent, and the limb appearing perhaps to be double its natural size. Large vesications or blebs, containing sero-purulent fluid, sometimes of a sanious tinge, make their appear- ance in many cases. This is the condition that usually continues up to the sixth or eighth day after the invasion of the disease, during the whole of which time the constitutional symptoms have presented the ordinary type of sthenic inflam- matory fever; about this time, however, a change commonly takes place, either for better or worse. If, under the influence of proper treatment, and in a tolerably healthy constitution, the inflammation subsides, resolution takes place, with a gradual abatement of all the symptoms. If, however, as usually happens, the disease runs on to more or less sloughing or suppuration of the part, no in- crease of the swelling, pain, or redness takes place, but, on the contrary, some diminution in these signs may occur, giving rise to an apparent, though decep- tive amendment in the patient's condition. The skin becomes darkly congested, and the part, instead of being tense and brawny, has a somewhat loose, soft, and boggy feel, communicating a semi-fluctuating, doughy sensation to the fingers. This change from a tense brawny state to a semi-pulpy condition is indicative of the formation of pus and slough beneath the integument, and should always be anxiously watched for by the surgeon. It must be remembered that it occurs without any material change in the size, the color, or the general appearance of the part, but can only be detected by careful palpation of it; hence the necessity of the surgeon daily examining with his own fingers the state of parts inflamed, and neither trusting to the reports of others, nor to the general ap- pearance of the diseased structures, for the probable condition of the subjacent tissues. If an incision be now made into the affected part, the cellular membrane will be found loaded with an opalescent fluid distending its cells, but not flowing from the wound; the retention of this fluid in the cellular tissue giving a gela- tinous appearance to the sides of the incision, which rapidly degenerate into slough and pus. If the alteration in structure have advanced to a stage beyond this, the cellular tissue will be found to have been converted into dense masses of slough, lying in the midst of thin and unhealthy ichorous pus; these have not inaptly been compared in appearance to masses of decomposed tow, of wet chamois leather, or to the membranes of a foetus a few months old. Whilst these changes are going on below the surface, the skin, at first congested, becomes somewhat paler, and assumes a white or marbled appearance, rapidly running into black sloughs, and being undermined to an immense extent by large quanti- ties of broken-up cellular tissue and of ill-conditioned pus, without any appear- ance of pointing, however extensive the subcutaneous mischief may be. These destructive changes expose muscles, fasciae, and blood-vessels, and may induce necrosis of the bones or destroy the joints. They occur most readily in those parts of the body that possess the lowest degree of vitality, and hence are more common in erysipelas of the legs than in the same affection of the scalp. If the patient recover, there will be tedious cicatrization of the deep cavities that are left, or considerable oedema, often of a solid character, a kind of false hypertrophy of the part, which may continue for some considerable time. In other cases again there may be such extensive local destruction or gangrene of the soft 372 ERYSIPELAS. tissues, with exposure and death of the bones or suppuration of the joints, that amputation of the limb may be required as a means of saving the patient's life. No operation of this kind, however, should ever be practised for the after-con- sequences of erysipelas, unless these be strictly localized with no tendency to spread, all specific constitutional fever having been completely removed, except such as is of a hectic character, and dependent on the exhausting influences of the suppuration and disorganization of the tissues. During the progress of these local changes, the constitutional symptoms have assumed corresponding modifications. At first of an acute inflammatory charac- ter, when suppuration and sloughing have set in, the fever often suddenly assumes an asthenic form, although in some cases there is no diminution in the severity of the symptoms, until after an attempt for a few days to bear up against the exhausting influence of the disease, the constitution gradually gives way, and death speedily supervenes. If the patient survive the stage of slough- ing, and if the discharge continue abundant, hectic with diarrhoea, gastro-intes- tinal irritation, metastatic abscesses or pyemia may carry him off. If recovery eventually take place, it may be at the expense of a constitution impaired and shattered for years. This disease is most dangerous in the old and infirm, or in young children. The immediate danger is always greatest when the head is affected, from the extension of the disease to the membranes of the brain, and the supervention of erysipelatous arachnitis. The remote danger from the effects of suppuration, necrosis, and inflammation of the joints, is greatest when the lower extremities are the seat of erysipelas. A variety of the cellulo-cutaneous erysipelas has been described as cedematous erysipelas. By this is meant not merely that effusion into the cellular tissue which occurs in all the varieties of the disease, but a peculiar form, specially marked by oedema of the cellular tissue, with less inflammation of the skin than usual. There is much swelling, which pits deeply, with but little pain or tension, and but moderate redness of the skin; the constitutional symptoms are less marked than in the other varieties of the disease; it is principally met with in old people, or in persons of a dropsical tendency, in whom it occurs especially about the legs, scrotum, or labia, sometimes giving rise, by the effusion of a sero- plastic fluid, to permanent and solid enlargement of these parts. 3d. The cellular erysipelas, or as it is often termed, diffuse inflammation of the cellular tissue, or cellulitis, is a disease that has been particularly described by Duncan, Arnott, Lawrence, and Nunneley. It always arises from a wound or injury, often, however, of an apparently trivial character, and most commonly affects the sub-cutaneous cellular membrane, though occasionally it extends to the sub-aponeurotic tissue, and then is a more severe and dangerous affection. Though commonly arising as a consequence of ordinary injuries, it is especially apt to follow those in which there has been any inoculation of animal poisons, as in dissection wounds, the stings of insects, and the bites of venomous reptiles. In whatever way arising, it is characterized by the rapidity and extent of the sloughing of the affected tissue, and by great depression of the powers of the constitution. That the diffuse inflammation of the cellular tissue, whether it is limited to a finger, or implicates the cellular membrane of half the body, is a variety of erysipelas affecting this membrane primarily, and the skin secondarily, there can be no doubt. The points of resemblance between cellulitis and ery- sipelas have been well shown by Nunneley. Not only are the local effects pre- cisely the same in the two diseases ; the same swelling, tension, infiltration of pus, and formation of gangrenous shreds and sloughs, but the constitutional symp- toms, though differing perhaps in degree, present no variety as to character. The results also are identical, there being the same impairment of structure locally, the same tendency to involve parts at a distance, and to the formation of secondary abscesses. So also these two diseases occur in the same constitu- tions, in the same states of the atmosphere, and in the same situation ; one form DIAGNOSIS AND PROGNOSIS OF ERYSIPELAS. 373 of disorder may produce the other, and, lastly, the same treatment is required for both affections. The symptoms of cellular erysipelas are great swelling, tension, and pain in the limb, which feels brawny in some parts, cedematous in others. The skin, which is slightly reddened in patches, has a mottled appearance, and speedily runs into blackish sloughs. The extent to which the disease may spread varies greatly; when once it has set in, it commonly runs rapidly up the whole of a limb, extending also to the sides of the trunk; in other cases, again, its vio- lence appears to be principally expended at a distance from the seat of injury; thus, in a case of a punctured wound of the finger, the diffuse inflammation may principally take place in the extended planes of cellular tissue about the axilla and sides of the chest. It is important to bear in mind that this form of ery- sipelas sometimes affects the internal planes of cellular tissue. This may happen, for instance, in the fasciae of the pelvis after lithotomy, or in the anterior medi- astinum after operations at the root of the neck. The sloughing often occurs with remarkable rapidity in the course of thirty-six or forty-eight hours, the cel- lular membrane being broken down into ill-conditioned pus and shreddy sloughs, more especially when the disease has resulted from the inoculation of an animal poison. Death may in such cases occur in two or three days; in other instances, again, several weeks elapse before a fatal result declares itself. The constitutional symptoms are those of asthenic fever in the most marked degree; a quick and feeble pulse, brown tongue, and muttering delirium, being early concomitants of this affection. The diagnosis of the various forms of erysipelas is generally easily made. From the exanthemata, it is distinguished by the character of the eruption, its limited extent, and usual complication with injury. From inflammation of the veins, or of the absorbents, the diagnosis is not always so easy, more especially as the two conditions frequently co-exist. If it be a vein that is inflamed, the general absence of cutaneous redness, the existence of a hard round cord, and the tenderness along the course of the vessel, are sufficient to establish the diagnosis. In inflammation of the absorbents, the redness will be found not to be uniform, but to consist of a number of small and separate red streaks, running in the direction of the lymphatics, and affecting the glands towards which they course; these two affections, however, erysipelas of the skin and inflammation of the absorbents, are almost invariably conjoined; hence a definite diagnosis is not of much importance. The prognosis in any case of erysipelas depends on a variety of circumstances. The form of the disease influences greatly the result, the cutaneous variety being attended with least danger, the cellular with the most. The traumatic is more dangerous than the idiopathic form. Much, however, depends on other circumstances, such, for instance, as the seat of the affection; that attacking the head and lower limbs being the most dangerous; when the head is affected, encephalitis being apt to ensue. When the legs are extensively implicated, sloughing of the skin and cellular tissue, with denudation of the bones and destruction of the joints, may occur. The disease, in all its forms, is most dangerous at either of the extremes of life. The previous state of health of the patient also influences greatly the result. If the constitution be sound, very extensive mischief may be recovered from; if, on the other hand, it is depressed or broken by want of the necessaries of life, by fatigue, over exertion, or in- dulgence in stimulants, a very slight amount of disease may probably prove fatal. The most dangerous complication of erysipelas, and one which when it exists almost precludes the hope of recovery, is a granular state of the kidneys with albuminuria. I have never seen any patient laboring under this disease, and attacked with erysipelas, escape with life; the sloughing and suppuration running on unchecked by any treatment that could be adopted. The particular 374 ERYSIPELAS. type the erysipelas may assume, and the occurrence of gastro-intestinal or pul- monary complications, will also seriously affect the result. Treatment of erysipelas. — The occurrence of erysipelas is best guarded against by attention to hygienic measures, more particularly to proper ventila- tion with pure air, and the avoidance of over-crowding of patients. In hospitals, erysipelas may be produced at will by want of attention in these respects, and it will usually be found that the persistence of erysipelas in certain wards, or even its repeated appearance in certain beds, is owing to some local cause, such as the emanations from a drain, on the removal of which the disease will cease. Scrupulous attention to cleanliness, also, on the part of nurses and dressers should be enforced, and the latter should not be allowed to go straight from the dead-house to the ward without previously washing their hands in some chlorinated solution. When erysipelas has already occurred, its further spread may be prevented by isolating the patients affected, and at once taking active measures to purify the ward from which they have been removed. The curative treatment of erysipelas must always be conducted with reference to the low character of the local inflammation, its tendency to run into suppu- ration and gangrene, the asthenic type that the constitutional fever readily assumes, and the frequent complication of visceral inflammations of a congestive form. The apparent intensity of the local inflammation must not lead the surgeon into the fatal error of employing an over-active antiphlogistic treat- ment, more particularly if the disease be epidemic, when it always assumes a low type. In the treatment of this affection, it is especially important to look to the future, and to remember that, if active depletory measures are employed early, with a view of lessening the present disease, it will be at the risk of inducing more extensive sloughing, and perhaps to lower the patient's powers to such a degree, as to prevent his bearing up under the depressing influence of the after-consequences. In the treatment of the cutaneous or simple form of erysipelas, we must in the first instance clear out the stomach and bowels by an ipecacuan emetic followed by a calomel and colocynth pill, and some saline aperient. If the patient be young, robust, and the disease be of a somewhat sthenic character, he should be kept on a mild diet, and have salines, with small doses of antimony, administered every fourth or sixth hour. If the patient be advanced in years, and the disease assume a lower form, no antimony should be given, but effer- vescing salines, or the acetate of ammonia in camphor mixture, may be admi- nistered. If the disease from the first assume a low type, or if it subside into this, the carbonate of ammonia in five or ten grain doses should be added to the preceding mixture, in which the decoction of bark may then be substituted for the camphor julep. In many of the low forms of erysipelas, medicines are not well borne by the patient, the stomach rejecting them, and then I have seen the best possible results follow the free administration of the brandy-and-egg mixture, to which I am in the habit of trusting in the majority of these cases. During the progress of the disease, simple purgatives must be given from time to time. When this form of erysipelas occurs in persons of a gouty habit, it may often be advantageously treated by the administration of colchicum in salines. The local treatment of this, as of every variety of erysipelas, is of equal im- portance with the constitutional management. Warm applications assiduously continued, especially poppy and chamomile fomentations applied by means of flannels or spongio-piline, afford the greatest possible relief. Cold lotions should never under any circumstances be employed : they not only act injuriously by lessening the vitality of the part, and thus favor local sloughing, but they may chance to cause a retrocession of the disease, and the consequent affection of some internal organ. The local abstraction of blood and of serum from the inflamed part, by the plan introduced by Sir B,. Dobson, of rapidly making TREATMENT OF ERYSIPELAS. 375 with the point of the lancet a large number of small punctures, from a quarter to half an inch deep, is of much value, by lessening the tension and swelling, and consequently diminishing the inflammatory action; a warm fomentation cloth or poultice should be laid over the punctures, so as to encourage bleeding and the escape of serum. Astringent applications to the inflamed surface, such as a strong solution of the nitrate of silver, are recommended by some surgeons. I have seen them pretty extensively employed by the late Dr. A. T. Thomson, but not with any very marked success. A boundary line of nitrate of silver is occasionally drawn around the inflamed part, with the view of checking the extension of the disease. I have often done this, and seen it done by others, but never apparently with any benefit; and have now discontinued the practice as a useless source of irritation. The application of a bandage is occasionally necessary after the disappearance of the erysipelas, in order to remove the oedema that results. In the treatment of the cellulo-cutaneous erysipelas, more energetic constitu- tional and local means are required than those just described. In the early stage of the disease, our object is to prevent the inflammation running into gan- grene of the affected tissues. The fever being at this period commonly of a sthenic character, the more active administration of purgatives, antimonials, or effervescent salines is required. I have never seen a case in which blood-letting is required, and strong antiphlogistics, such as salines, should be given with great caution. The best plan is, perhaps, to give an emetic and purge, to clear out the stomach and bowels, and then to give effervescing salines with carbonate of ammonia, in full doses, gr. x. to gr. xv. As the disease advances, and symp- toms of more or less depression come on, it may be necessary to effect that gra- dual change from a depletory to a stimulating plan of treatment that has already been described in speaking of the management of inflammatory fever; in doing this, the pulse and the tongue must be our guides; as the one becomes feebler and the other browner, so must ammonia, bark, and especially port-wine, and the brandy-and-egg mixture, be administered. In the more advanced stages of the disease, when sloughing and suppuration are fully established, our sole object must be by nourishing diet, and the use of stimulants and tonics, to bear the patient through the depression and subsequent hectic that ensue. The local treatment of the cellulo-cutaneous or phlegmonous erysipelas, must be conducted on essentially the same plan as that of the cutaneous variety, though with the employment of more active means. The part affected must be kept at rest, must be elevated if it be a limb, and have hot chamomile and poppy fomentations assiduously applied, cold being more prejudicial here even than in the last form of the disease; in this way, the swelling and tension may perhaps be removed, and the sloughing of the cellular tissue prevented. In the majority of cases, however, other means will be required to effect this, and with this view none are more efficacious than incisions made into the part; by these an outlet is afforded for the blood and effused serum, which, by distending the ves- sels and cells of the part, produce strangulation of its tissues and consequent sloughing. This mode of practice, originally introduced by Mr. C. Hutchinson, is generally allowed to be the most effectual means we possess for the preven- tion of sloughing; hence the incisions should be made early, before there has been time for the tissues to lose their vitality. So soon, indeed, as they have become brawny, indurated and tense, incisions properly made and placed will afford the greatest possible relief to the part and the patient, taking down the tension by their gaping, and the swelling by the exit they afford to blood and serum. Much difference of opinion has existed among surgeons, as to the extent to which incisions should be practised in these cases. Some recom- mending that one long cut should be made through the inflamed structures; others contending, on the contrary, that a number of small incisions better answer the proposed end. The objections to the long incision are, that so con- 376 ERYSIPELAS. sidierable a wound not only inflicts a serious shock upon the system, but that the loss of blood from it is often so great as to be of serious, and even of fatal consequence to the patient, cases having occurred in which life has been lost from this cause, or the hemorrhage only arrested by the ligature of the main artery of the limb,—and also that a single long incision does not relieve tension so effectually as a number of smaller ones. The incisions consequently should be of limited extent, from two to three inches in length: at most they should not extend deeper than into the gelatinous looking subcutaneous cellular tissue, unless it happen that the disease have extended beneath the fascia, when they may also be carried through it. Mr. South recommends that the incisions should be so arranged in fours, as to enclose a diamond-shaped space, and states that in this way the greatest relief is given to the tension | I of the part: after the incisions have been made, the part should be well poulticed and fomented so as to facilitate the escape of serum. As it is not the object of the surgeon to draw blood in these cases, any undue amount of hemorrhage should be arrested by plugging the wound. After suppuration and sloughing have taken place, as indicated by a boggy feel of the parts, free incision should be made in order to let out pus and sloughs. After this the skin will often be found to be greatly undermined, blue, and thin, with matter bagging in the more dependent parts; if so, egress must be made for it by free counter-openings. During the after-treatment frequent dressing is necessary so as to prevent an accumulation of pus, and the sloughs must be removed as they form. Care should be taken not to destroy any of the vascular connections of the skin with subjacent parts, but in order to get proper cicatrization it will often be found necessary to Jay open sinuses, or to divide bridges of unhealthy and blue integument stretching across chasms left by the removal of the gan- grenous cellular tissue. If the loss of substance be great, the cicatrix that forms may be weak, imperfect, or so contracted as to occasion great deformity of the limb. In other cases, again, the diseased state of the bones and joints may be such as to call for ultimate amputation, either in consequence of the local deformity and annoyance, or in order to free the constitution from a source of hectic and of irritation. Under all circumstances, the patient's health will usually continue in a feeble and shattered state for a considerable time aftei recovery from this form of erysipelas, requiring change of air and great atten- tion to habits of life, a nourishing diet, &c. In the treatment of the cellular variety of erysipelas, it is usually necessary to administer stimulants early; ammonia, wine, or brandy may be required from the very first. The surgeon must judge of this by the constitutional condition of the patient, and more particularly by the state of his pulse and tongue. The local treatment is precisely of the same kind as that adopted in phlegmonous erysipelas, except that the incisions require to be made earlier and perhaps more freely; in all other respects, there is no difference between the general manage- ment of the two forms of the disease. SPECIAL FORMS OF EXTERNAL ERYSIPELAS. Erysipelas of newly-born infants is occasionally met with, more particularly in lying-in hospitals, or in situations where the mother and child are exposed to depressing causes of disease. It usually makes its appearance a few days after the birth, at first about the abdomen and genitals, but spreads rapidly over the whole of the body, being characterized by a dusky redness, which rapidly runs into gangrene of the affected tissues. It has been supposed to arise from inflammation of the umbilical vein, or of the umbilicus itself. It is an extremely fatal affection, owing to the feeble vitality of the child, and presents but few points for treatment; change of air and of nursing, with the administration of SPECIAL FORMS OF ERYSIPELAS. 377 a few drops of Sp. ammonia or brandy from time to time, being all that can be done. Phlegmonous erysipelas of the head is of very frequent occurrence from slight injuries or operations about the scalp and face, more particularly in elderly people and those of unhealthy constitution. In this form of erysipelas there are two special sources of danger; one is from sloughing of the occipito-frontalis muscle, the other from inflammation of the membranes of the brain. The occipito-frontalis sloughs, in consequence of the pressure to which it is subjected by the swelling of the planes of cellular tissue between which it lies; and the encephalitis occurs apparently by the extension of the inflammation inwards. In the treatment of this affection more active antiphlogistic means, such as vene- section, with salines and antimony, are required than in the management of other forms of erysipelas. With the view of preventing sloughing of the muscle, a free crucial incision should be made through the scalp down to the bone, the head, of course, having been shaved at the onset of the disease. Bagging of matter must be prevented by free counter-openings, and the appli- cation of pads and bandage wherever it is likely to occur. However much the scalp may be undermined, or the bones of the cranium exposed, adhesion usually takes place, and the vitality of the parts is preserved. Erysipelas of the scrotum, the "inflammatory oedema," so well described by Liston, is of frequent occurrence, as the result of wounds, ulcers, and other sources of irritation in this neighborhood. In this affection the scrotum swells to a large size, being uniformly red, but with a semi-transparent glossy appear- ance, pitting readily on pressure, and feeling somewhat soft and doughy between the fingers; the integuments of the penis are also greatly swollen and cedema- tous, and sometimes the inflammation extends to the cellular tissue of the cord. The chief characteristic of this form of erysipelas is its tendency to run into slough without any previous brawny or tense condition of the parts, the dartos becoming so distended with sero-plastic fluid that the circulation through it is arrested and its tissue loses its vitality. When an incision is made into it in this condition it scarcely bleeds, and the sides of the wound present a yellowish- white gelatinous appearance. The treatment of erysipelas of the scrotum is simple; it consists in making a free incision about four inches in length from behind forwards on either side of the septum, taking care, of course, not to go so deep as to wound the testes; the part must then be supported on a pillow, and well poulticed and fomented. If this incision be not made at once, a great part, or even the whole of the scrotum may slough away, leaving the testes and cord bare; under these unpleasant circumstances, however, the parts will often with great rapidity cover themselves with a new integument. The oedema of the penis usually subsides of itself, or by making a few punctures in it; should its integuments, however, threaten to slough, a free incision must be made into it, or the prepuce be slit up. Erysipelas of the pudenda is occasionally met with in ill-fed unhealthy children in whom cleanliness is neglected. The parts become of a dusky or livid red, swell considerably, and quickly run into gangrene, which spreads up the abdomen or down the nates. It may prove fatal by inducing peritonitis or exhaustion. In the treatment, ammonia, bark, and the chlorate of potass, with good nourishment, and a little wine, are the principal means to be em- ployed, at the same time that yeast or chlorinated poultices are applied locally. Erysipelas of the fingers, or as it is commonly called " whitlow," is a frequent affection in old and in young people, either occurring spontaneously in cachec- tic constitutions, or arising from the irritation produced by scratches, punc- tures, or the inoculation of the part with poisonous or putrescent matters. It is most common in the spring of the year, when, indeed, at times it appears to be epidemic, large numbers of persons suffering from it without any very appa- rent local cause. 378 ER YSIPELA S. That whitlow is truly an erysipelatous affection of the fingers appears to be the case for the following reasons: — lstly. Because the causes, whether of season, infection, or local irritation, appear to be the same in both affections. 2dly. The constitutional disturbance is always very severe for so slight a dis- ease, and assumes the same character of speedy depression that we observe in erysipelas. 3dly. The inflammation of the affected finger is invariably diffuse, never being bounded by adhesion, but always tending to terminate in suppura- tion and sloughing. And, lastly, so soon as the disease spreads beyond the affected finger, or to the back of the hand, it assumes a distinctly erysipelatous appearance and character. The inflammation of whitlow is in many cases confined to the pulp of the finger, commencing in the dense cellulo-fibrous tissue forming this, and often arising from a very slight injury, as the prick of a pin or splinter, but not unfrequently without any traumatic cause. The part becomes extremely pain- ful, hard, red, and swollen; it then suppurates to a limited extent, with some sloughing of the cellular tissue. In many cases the ungual phalanx, which is imbedded in the cellulo-fibrous digital pulp, necroses when this sloughs; there is usually some inflammation of the lymphatics of the arm accompanying this affection, and not unfrequently a good deal of constitutional fever and irritation. In the more severe cases of whitlow, the inflammation, which is of an exces- sively painful character, owing probably to the tension of the parts, extends to the sheaths of the tendons, and. then constitutes an affection that is fraught with danger to the utility of the finger or hand. In these cases the whole finger swells considerably, becomes red and tense, with much throbbing and shooting pain; the inflammation rapidly extends to the dorsum of the hand, which becomes puffy, red, and swollen, presenting the ordinary characters of erysipelas. Although the palm be greatly swollen, it usually preserves its natural color, or becomes of a dull white, owing to the greater thickness of the cuticle in this situation. Pus rapidly forms, both in the finger and hand, and finding its way into the sheaths of the tendons, will spread up the forearm under the annular ligament. There is usually no fluctuation to be felt in the finger, even though pus may have formed, but in other parts of the hand it may readily be detected in the usual way. In these cases there is always much sloughing conjoined with the suppuration, the cellular tissue of the finger and hand, the tendons or their sheaths, and the palmar fascia, being all more or less implicated. In many cases the joints of the fingers are destroyed, and the phalanges necrose, or if this do not happen, the tissues of the part may be so matted together as the result of sloughing and suppuration, that rigid and con- tracted fingers, or a stiff and comparatively useless condition of the hand, may be permanently left. In the treatment of this affection, the patient should be well purged, and kept upon a strictly antiphlogistic plan during the early stages. At the same time the inflamed finger should be freely leeched, and then alternately poul- ticed and soaked in very hot water for twenty-four or forty-eight hours, being kept during the whole of this time in an elevated position. In this way the inflammation may be sometimes cut short at its onset; should it, however, con- tinue to progress, the finger becoming hard, with much throbbing, a free longi- tudinal incision must at once be made along either side of it, so as to relieve tension and prevent sloughing; this, though a painful procedure, should never be omitted, on account of the importance of the preservation of the full utility of the part. The incision is best made from the proximal towards the distal end of the finger, so that if the patient make an attempt to withdraw the hand during the operation, he will rather facilitate the cut being made than other- wise. In making these incisions, however, the sheaths of the tendons should, if possible, be avoided; if these be opened, the tendons will probably slough, INTERNAL ERYSIPELAS. 379 and the finger be left in a permanently extended and rigid state. The finger must then be well soaked in hot water, and poulticed. In this way the inflam- mation may be arrested, and sloughing happily prevented; should, however, matter have formed, this must be let out as it accumulates, and all hardened and sodden cuticle peeled from the part. After the opening has been made, and any sloughs that have formed come away, it not unfrequently happens that a large and fungoid granulating mass sprouts up; this will, however, gradually subside, as the swelling of the finger goes down and the inflammation abates. If the nail become loosened, it had better be removed, as it may otherwise keep up irritation; it must not, however, be torn off if adherent, but then merely scraped and cut away so far as loose. When the whole of a finger is affected, the hand should be placed on a pasteboard splint so soon as the inflammation has been somewhat subdued, lest contraction of the affected finger ensue, which may eventually extend to the neighboring ones. When the joints are implicated, destruction of the cartilages commonly ensues, but yet, by position, and rest on a splint, a tolerably useful, though stiffened finger may be left. When the bones are implicated, some operative procedure usually becomes eventually necessary. If the ungual phalanx alone be necrosed, it may be excised through an incision on the palmar side of the finger, the pulp and nail being left; in this way I have often preserved a finger that must other- wise have been removed. Amputation of the finger of the metacarpo-phalan- geal articulation will usually be required when the second or proximal phalanges are involved, though here, partial operations by cutting and scraping away the diseased bone, may sometimes be usefully done. During the later stages of these affections, tonics, good diet, and stimulants will be required for the re-es- tablishment of the health. INTERNAL ERYSIPELAS. By internal erysipelas is meant those forms of diffuse inflammation which affect the mucous or serous surfaces, or the lining membrane of arteries, veins, lymphatics. The mucous surface that is chiefly affected by this disease is that covering the fauces, the pharynx, or the larynx. Erysipelas of the fauces may occur in consequence of the disease spreading from the head and face to these parts, or it may commence as a primary affec- tion, occurring perhaps at the same time that the rash appears on the cutaneous surface on some distant part of the body. When the fauces are erysipelatous, they present a bright crimson or scarlet color, with some swelling and thicken- ing of the soft palate and uvula; there is also most commonly some huskiness or complete loss of voice, and occasionally some croupy symptoms. At the same time there is a good deal of low constitutional fever, with a pungent, hot skin, and quick pulse. This form of erysipelas is of a peculiarly contagious character, and occurs not unfrequently in the attendants of those who are laboring under some of the other varieties of the disease; of this I have seen numerous in- stances. In many cases, also, it is epidemic, spreading through a house, and affecting almost every inmate. In the treatment of this affection, the best results are obtained by sponging the inflamed parts freely with a strong solu- tion of the nitrate of silver; and, if there be much constitutional depression, administering full doses of ammonia, with camphor or bark. Should the dis- ease go on to sloughing, constituting some of the forms of" putrid sore throat," which not unfrequently happens, the mineral acids and bark, with chlorinated port-wine gargles, and the brandy-and-egg mixture for support, will be found most useful. In many cases, tlris disease continues limited to the palate and fauces; but in others it extends either upwards or downwards. It may extend upwards through the nares, out of the nostrils, and thus spread over the face 380 ERYSIPELAS. and head. It may extend downwards, affecting the gastro-intestinal membrane, or more frequently implicating the larynx. Erysipelatous Laryngitis, as described by Byland, Budd, and others, is an extremely dangerous affection. The inflammation in these cases commencing in the fauces, rapidly spreads to the mucous membrane and loose submucous cel- lular tissue, external to, and within the larynx, giving rise to extensive cedema- tous infiltration of these parts with sero-plastic fluid, which, by obstructing the rima o-lottidis, may readily suffocate the patient. In consequence of this spe- cial tendency to oedema, the disease has by many writers been termed "cedema- tous lartnujitis." After death, in these cases, the submucous cellular tissue of the fauces, that about the base and fraena of the epiglottis, and especially that which covers the posterior part of the larynx, will be found to be distended with serum or a sero-puriform fluid. This infiltration occupies the rima of the glot- tis, and extending into the interior of the larynx, gives rise to such swelling that its cavity is nearly obliterated. Great as the swelling may be, however, in all these parts, it never spreads below the true vocal chords. This fact, which is of considerable importance, is owing to the mucous membrane coming closely in contact with, and being adherent to, the fibrous tissue of which these are composed, without the intervention of any submucous cellular tissue. The pro- gress of this oedematous inflammation of the mucous membrane, and loose sub- mucous tissue in these situations, is often of an amazingly rapid character, the swelling being sufficient to induce suffocation at the end of thirty-six or forty- ei^ht hours, or even sooner. If the patient be not carried off in this way, there will be a great tendency to suppuration and sloughing of the affected tissues, leading perhaps eventually to death from absorption of pus, and low constitu- tional fever. The symptoms of this affection are strongly marked: the patient, after being attacked with erysipelas of the fauces, attended by some difficulty and pain in deglutition, with huskiness of the voice, is seized with more or less difficulty in breathing, coughs hoarsely and with a croupy sound, and complains of tender- ness under the angles of the jaw and about the larynx. The difficulty in breath- ing increases, and may speedily threaten the life of the patient, giving rise to intense fits of dyspnoea, in one of which he will probably be suddenly carried off. On examining the throat from the interior of the mouth, the fauces will not only be observed to be much and duskily reddened, but by depressing the tongue the epiglottis can be felt, and perhaps seen, to be rigid and erect. In the treatment of this affection local means are of the first importance. The tongue having been well depressed, the posterior part of the larynx, the epiglottis and its fraena must be well scarified by means of a hernia knife, with which this operation may be most readily and safely done. The patient should then be directed to inhale the steam of hot water, and a large number of leeches may be applied under either angle of the jaw, to be followed by large and hot poultices; at the same time, the bowels must be kept well opened, and the patient treated antiphlogistically or otherwise, according to the condition of the constitutional fever. Most frequently, in these cases, I have found antimonials of great ser- vice in the early stages, followed at a later period by support and stimulants. A few hours after the engorged tissues have been unloaded by scarification, the fauces, pharynx, and upper part of the larynx should be well sponged out with a strong solution of the nitrate of silver (^i. to §i.) which must be applied freely, coagulating the mucus, and taking down the increased vascular action. If, understanding the employment of these means, the dyspnoea increase, the face becoming pale, livid, and bedewed with a clammy perspiration, it will be necessary, in order to save the patient from impending suffocation, to open the windpipe. In doing this I prefer the operation of laryngotomy, for reasons that will be mentioned when I come to speak of the diseases and operations of the air-passages. In order that this operation should be successful, it must not, PURULENT INFECTION, OR PYEMIA. 381 however, be too long delayed, and should not be looked upon as a last resource; if done in time, and time in these cases is most precious owing to the rapid pro- gress of the disease, the patient's life may probably be saved; but if deferred too long, congestion of the lungs will have come on, the blood will cease to be properly arterialized, and the patient will sink from a slow asphyxia, even though air be at last freely admitted. If the patient survive to the stage of sloughing, chlorinated gargles and support must be our chief reliance. Erysipelas of the serous membranes is of common occurrence in surgical practice, being frequently met with in the arachnoid and peritoneum. These, like all other serous membranes, are liable to two distinct forms of inflamma- tion, one, which is of a sthenic character, having a tendency to the formation of plastic lymph; the other, which is of a diffuse or erysipeloid form, being always accompanied by the exudation of a plastic unorganizable fibrine. Erysipelatous or " diffuse" arachnitis commonly occurs as a consequence of injuries of the head and erysipelas of the scalp. In these cases there is usually a flushed countenance, bright staring eyes, low muttering delirium, alternating with a comatose condition, and rapidly terminating in death; the constitutional symptoms are those of low irritative fever. On examination after death, the arachnoid and pia mater will be found greatly injected with blood, forming a close red net-work of vessels over the surface of the brain, the substance of which is usually somewhat injected, the ventricles being distended with a red- dish-colored serum. If examined at a later period in the disease than this, the inflamed arachnoid will be found to be covered with a layer of opaque puriform lymph of a greenish-yellow color and slimy consistence. Erysipelatous or "diffuse" peritonitis is not unfrequently met with in aged and cachectic subjects after the operation for hernia, or as a consequence of various diseases and injuries of the pelvic or abdominal organs. In this form of peritonitis, the symptoms are often of a latent character, the disease being chiefly indicated by obscure pain diffused over the abdomen, with tenderness on pressure, and an anxious depressed countenance, a hot skin, and a small and rather hard pulse. On examination after death, the subperitoneal cellular tissue will be found injected, the peritoneum opaque in parts, covered with filmy patches of greyish lymph, and usually containing a largish quantity of opaque dirty-looking turbid fluid, mixed with shreds and flocculi of lymph. This, though closely resembling pus in appearance, is serum with lymph intermixed, and is of a peculiarly acid, acrid, and irritating character. It is this form of peritonitis that is so dangerous to dissectors; inoculations of the fingers with any of this fluid being often productive of the most serious and even fatal consequences. The erysipelatous inflammation of the lining membranes of the vascular sys- tem, will be fully discussed when we come to consider diseases of these parts. CHAPTER XXVIII. PURULENT INFECTION, OR PYEMIA. By pyemia is meant a dangerous and often fatal affection, supposed to depend upon the admixture of pus with the blood. This disease is closely allied to some of the lowest and worst forms of erysipelas, with which indeed it is com- monly associated, and to which it presents great similarity in its causes, symp- toms, and effects. 382 PURULENT INFECTION, OR PYEMIA. Like erysipelas, pyemia commonly occurs at those seasons of the year, and under those atmospheric conditions in which diseases of a low type are preva- lent, frequently as the result of overcrowding in hospitals, and it is in unhealthy and cachectic constitutions that it usually manifests itself. Though it is least frequently met with during the earlier periods of life, yet it may make its ap- pearance at any age, and I have seen very young children carried off by it. Pyemia is never, I believe, an idiopathic or primary affection, but either occurs subsequently to an injury or wound of some kind by which inflammation is excited, which has in most cases reached the stage of suppuration before the pyemic symptoms come on; or in connection with some low form of suppurative inflammation. Thus we often see boils, carbuncles, diffused abscess, erysipelas of the skin, or erysipeloid inflammation of the veins or absorbents precede its occurrence. Wounds of veins, of bones, and of joints, are the injuries that are especially apt to be followed by this disease; and in the puerperal state it is often met with, probably as the result of uterine phlebitis. Pyemia is characterized specially by two series of phenomena. The first is a state of great depression of the powers of the system; the second, the forma- tion of abscesses in various parts of the body. The symptoms are as follow: — The patient is seized with rigors, usually of a very severe and continuous character, but occasionally short and transient, sometimes occurring irregularly, at others being repeated almost periodically twice or thrice in the twenty-four hours, for some days in succession; in some cases these rigors are not attended by any sensation of cold, but in others they are, and then alternating with much febrile disturbance resemble very closely an ague fit; any open wound that may exist at this time usually becomes foul, sloughy, and ceases to secrete pus, though I have seen it continue healthily granulating throughout the dis- ease. The skin is hot, and has a burning pungent feel. The breath has that peculiar sweetish, saccharine or fermentative smell that is commonly noticed in all febrile diseases of a low type; this odor of the breath, and indeed of the body generally, often occurs early in the disease, and must then be taken as a very unfavorable sign. The secretions are arrested, the pulse is quick and feeble, the face is usually pale, with a very anxious drawn look, but sometimes flushed and the eyes bright; there is hebetude and dulness of mind, with slight nocturnal delirium, but perfect consciousness on being spoken to; about this period, patches of erratic erysipelas frequently make their appearance on the surface, and the skin assumes a dull, sallow, and earthy, or a bright yellow, icteric tint, which may extend even to the conjunctivae. The symptoms now indicate an extreme depression of the vital powers, the pulse becoming small and fluttering, the tongue brown, with sordes about the teeth, and low delirium; usually from the sixth to the tenth day, but sometimes earlier, diffuse suppura- tion begins to take place in different tissues, joints, and organs. This may occur in the viscera without occasioning any.material pain; if seated in the cellular tissue, or in the substance of muscles, there is much doughy swelling, with some redness; if in the joints, the swelling is often considerable, the pain usually intense and of a very superficial and cutaneous character, the patient screaming loud with the agony he suffers. These pains, which are chiefly seated in the knees, ankles, hips, and shoulders, often simulate rheumatism very closely. The progress of the disease is usually from bad to worse, sometimes rapidly, but at other times not uninterruptedly so, there being remissions and apparent, though not real, improvement. The patient rapidly wastes, the body becoming shrunken, the muscles soft, and the skin loose and pendulous; great debility also sets in. The abdomen becomes tympanitic, diarrhoea or profuse sweats come on; pneumonia or pleuritic effusions declare themselves ; delirium, from which the patient is easily roused, alternates with sopor, and at last he sinks from exhaustion. Death usually takes place about the tenth or twelfth day, SYMPTOMS OF PYEMIA. 383 though it may occur as early as the fourth, or the patient may linger on for six or seven weeks. In other cases pyemia occurs in a very insidious manner, without rigors, but merely with prostration, and some low fever of an intermittent kind; after a time the skin assumes a yellow tint, as do the conjunctivae. The urine is very high-colored, and perhaps the peculiar odor in the breath or body may be noticed; but the patient continues in a quiet state, his wound clean, and sup- purating healthily. He gets, however, symptoms of low pneumonia or pleurisy, with, perhaps, pain and fulness in one joint, where abscess forms, and then the disease fully declares itself. The formation of numerous purulent deposits, "secondary or metastatic abscesses," as they are often termed, is one of the most marked features of pyemia. These abscesses usually contain a somewhat thin and oily-looking pus; at other times, however, it is thick and laudable. The more oily-looking fluid, though opaque and yellow, and closely resembling true pus, will, on micro- scopic examination, be found to differ from this in the absence of the true nucleated pus-corpuscle, though it contains an immense number of granular cells (figs. 49 and 50.) After removal it often forms a firm fibrinous coagulum. These purulent collections vary greatly in size and in situation, they are found in the viscera, in the cellular and muscular structures, in the serous membranes, and in the joints. Pyemic abscesses differ from ordinary purulent collections, not only in the peculiar character of the pus that they contain, but more particularly in the rapidity with which they form, a few days commonly sufficing for them to attain a large size. So, also, their very widely-spread character, and the insidious manner in which they occur, — the tissues, as it were, breaking down without any inflammation, — constitute the distinguishing features of these collections. The visceral abscesses vary in size from a pin's head to a walnut; in many cases the organs affected are studded with them. These collections are most frequently met with in the lungs, being seated on the surface of the organs, or in the interlobular fissures, next, in the liver, and then, in the.spleen; they are usually surrounded by a darkly-inflamed and condensed layer of tissue, which forms an imperfect wall to the collection. They may occur in other organs; thus, my friend, and late house-surgeon, Mr. Gamgee, has on several occasions observed them in the prostate. When the pus is infiltrated into the cellular tissue and muscles of the limbs and trunk, it will form immense diffuse collections of a thin and serous matter, commonly mixed with shreds of the cellular membrane of the part. These col- lections are most frequently met with, perhaps, in the axilla, down the flank and about the back, in the iliac fossa, thigh or calf, and may either be confined to the subcutaneous, or extend to the deep intermuscular cellular planes in these regions; or may even form in the muscular substance itself, being diffused between the fasciculi which are softened and disintegrated. Most commonly the presence of these collections is indicated by patches of cutaneous or erratic erysipelas, and by a doughy, cedematous, and boggy state of the superjacent integuments. Accumulations of pus in the serous and synovial membranes are common in this disease; the arachnoid, the pleura, or the peritoneum may all be affected in this way. More frequently, however, some of the joints, especially the knees and shoulders, become filled with a thin, yellow, purulent liquid. These arthritic abscesses are usually indicated by the occurrence of intense pain, often of a cutaneous or superficial character, with fluctuation and swelling in the articula- tion affected. It often happens, however, that large accumulations of pus form suddenly in joints, without having been preceded by pain or any other sign of mischief; in these cases the interior of the joint, though filled with pus, will be found to be tolerably healthy, there being no erosion of cartilage or destruc- 384 PURULENT INFECTION, OR PYEMIA. tion of ligament, but merely some inflammatory injection of the synovial membrane. Not only are the appearances just mentioned commonly met with in cases of death from pyemia, but we find the viscera, more particularly the brain and lungs inflamed, and, not unfrequently, a diffused erysipelatous redness of some membranous surface, as of the arachnoid or gastro-intestinal mucous membrane. The diagnosis of pyemia is not always easy in the earlier stages, when the rigors, depression, and other signs of constitutional disturbance may be looked upon as common to other intercurrent diseases. As the affection declares itself, however, the continuance and severity of the rigors, the extreme want of power, the icteric tinge of the skin, the peculiar faint and sickly odor of the breath, and the occurrence of metastatic and visceral abscesses, indicate the true nature of the attack. The question necessarily arises, to what are the symptoms and destructive effects of pyemia due ? There can be little doubt that they are owing to the alterations that take place in the blood itself. It is only in this way that the remarkable diffusion of the disease, the variety of tissues affected, and the wide- spread tendency to suppuration that characterizes it can be explained. That the blood undergoes important changes in this disease is unquestionable; it is thin, dark-colored, and, after having been drawn from the body, forms a loose, spongy coagulum, from which a moderate quantity of rather turbid or milky-looking serum separates. On examination under the microscope it will be found that, besides the ordinary red corpuscles, the blood contains, often in large quantities, corpuscles, that in some cases closely resemble the ordinary white ones of the healthy blood, and at others present such exact similitude to the pus-cell, that the most practised eye fails in detecting a difference. These corpuscles may be few in number, and at other times so abundant that they occupy the field of the microscope to the exclusion of the red. The existence of these corpuscles in the blood, which I believe will invariably be found on careful examination, more especially in that taken from the larger veins, constitutes apparently one, if not the essential element of the disease. That they are true pus-corpuscles, in many cases, would seem to be probable from their microscopic appearances; in others again, they do not present the characters of the true pus-cell, differing from it in the shape, or in the absence of a nucleus, and in their more irregular outline; resembling indeed more closely the white corpuscles, or some of the ill-developed granulation or exudation-cells that are met with in cold or lymphatic abscesses occurring in cachetic constitutions. Whatever differences of appear- ance these corpuscles may present, they can best be compared to those pus-cells that are found in many unhealthy abscesses, and more especially in the diffuse purulent collections occurring in the cellular tissue or the joints in this very disease; and like these I think we must look upon them as products of inflam- mation, though perhaps of a low and aplastic form. The question that next presents itself is, how do these corpuscles find their way into the blood ? and how do the other changes that occur in the physical characters of this fluid take place ? By some surgeons it has been supposed that the pus is actually and bodily absorbed from the surface of the suppurating wound, and so admixed with the blood. This explanation, however, is not tenable, as there is not only no proof, but no reason to believe in the possibility of the absorption of a pus-corpuscle in its state of integrity from the surface of a wound. Then, again, it has been supposed that the pus having trickled, or in some other way found an entrance into the open mouth of a divided vein, as upon the surface of a stump or in a sawn bone, has gained access to the general circulation. But it is difficult to understand how pus can possibly become admixed with the general current of the blood in this way; for if the vein be sufficiently open to allow of the entry of one fluid, it would certainly be so to admit of the escape of the other. The theory that has the most advocates at CHANGES IN THE BLOOD IN PYEMIA. 385 the present day, is, that the pus enters the circulation as a consequence of phlebitis, being formed directly by the lining membrane of an inflamed vein, and thus poured at the moment of its evolution into the current of blood passing along the vessel. This dependence of pyemia on suppurative phlebitis, more especially of a diffuse character, has been strongly advocated by Hunter, Arnott, Berard, and others, and affords an easy solution to the difficulty, and has acquired considerable weight from the fact that in many cases these affections are found co-existing. I am by no means prepared to deny that the pus does in all probability in very many cases become directly admixed with the blood in this way, and that suppurative phlebitis is consequently in these instances the cause of the pyemic symptoms. This explanation would indeed be conclusive, if it could be shown that phlebitis was the only, or even the most frequent form of diffuse inflammation occurring in connection with pyemia, and that it always took place as a precursor and concomitant of the blood affection. But this I believe not to be the case. I have had opportunities of examining the bodies of a considerable number of patients who have died of pyemia, and I have certainly often found evidence of other diffuse inflammations as well as of phlebitis; and in some cases no inflammation of the veins could be detected on the most careful investigation specially directed to this point; and hence I cannot but come to the conclusion that pyemia, though frequently co-existing with, may occur independently of suppurative phlebitis, and cannot in all cases be necessarily considered a consequence of that disease. Tessier maintains that pyemia is always independent of phlebitis, being a primary blood disease. The doctrine, however, is irreconcilable with the established fact, as pointed out by Sedillot, that the injection of pus into the blood produces a disease identical with pyemia; that this affection is always preceded by local inflammation, and usually by suppuration, and that a distinct connection has been pointed out by Hunter, Arnott, and Berard between sup- purative phlebitis and pyemia. Besides this, the presence of cells in the blood resembling the pus-corpuscle admits of proof. In the very excellent essay published by Mr. Henry Lee on this subject, that surgeon expresses his opinion that the introduction of pus into the system from an inflamed or injured vein is rarely the first step in purulent infection, but must have been preceded by some change that has taken place in the blood, by which its coagulating power has been impaired. Mr. Lee's views are supported by a number of ingenious experiments. How are we to account for the changes that the blood undergoes, and which whether resulting from suppurative phlebitis or not, are the essential causes of the pyemic symptoms ? The explanation that I would suggest as to the cause of the presence of the true or imperfectly formed pus-cell in the blood in these cases is the following. For pyemia to occur, I believe it to be invariably and absolutely necessary that a local inflammation previously exist in some part of the body. This may either be external or internal; it may be limited in size to that of a boil, or it may be as extensive as the surface of a sloughy stump. In all cases this inflammation is of, or tends to assume, a suppurative character; and in all, the constitution is broken, and of that kind in which the corpuscular or aplastic lymph commonly forms. It is not difficult to suppose that the blood in circu- lating through the part so diseased, instead of undergoing those peculiar changes that are impressed upon it in its passage through tissues that are sthenically inflamed, and of which the most remarkable is the formation in it of a large quantity of plastic filamentous fibrine, — as evidenced by the hard firm coagulum, by the formation of the buffy coat, and by the tendency to the deposition of coagulable lymph, as well as by the occurrence of constitu- tional fever of the sthenic type, — may undergo alterations in composition, of equal extent, though of a far different kind. It appears not improbable that 386 PURULENT INFECTION, OR PYEMIA. the fibrine formed in the blood in these low inflammations, occurring in broken constitutions and at unhealthy seasons, may assume that corpuscular or aplastic character which we have already seen to be the invariable result of these con- ditions, and that the corpuscles, which are met with intermixed in greater or lesser quantity with the blood in pyemia, and that bear a sufficiently close resemblance to granulation or exudation-cells, to all the various forms of the unhealthy, and occasionally to the typical variety of the pus-corpuscle, are in reality the conditions under which superfibrination of the blood with corpuscular lymph would necessarily show itself. That, consequently, instead of being formed from without, and absorbed or poured into the blood, they are actually generated in that fluid itself during its passage through the unhealthy-inflamed tissue, not however by any conversion of the blood-globule into a lymph or pus- cell, but as a consequence of those changes which we know, by their effects, to be impressed upon the blood by circulation through inflamed tissues, but with the precise nature of which we are still unacquainted. It is also by these blood- changes in pyemia that we may account for the remarkable constitutional depression that exists; for if, as there is every reason to believe, the admixture of plastic fibrine with the blood will occasion sthenic inflammatory fever, the formation of aplastic exudation-matter in that fluid may occasion a correspondingly low type of constitutional disturbance. As the blood circulates through an inflamed vein, not only would those changes take place in it that occur in its passage through other tissues, but it would thus become mechanically mixed with the pus and exudation-matters poured out in large quantity by the lining membrane of the vessel; and hence we may explain the greater liability to the occurrence of pyemia after or in combination with suppurative phlebitis, than in connection with any other inflammatory affection elsewhere situated. When once these corpuscles are admixed with the blood, it is probable that abscess is a necessary result from their mechanically occluding the capillaries, as Cruveilhier long ago showed experimentally to be the case. The pus-cells, being larger than the blood-corpuscles, become arrested in the capillaries of organs, and thus constitute points of irritation, around which inflammation is set up, and in which suppurative action takes place; these changes being first induced in those organs, the capillaries of which are of a very small calibre, as in the lungs. The tendency to suppuration of joints, and to the formation of diffused col- lections in the muscles and cellular tissue, can scarcely, however; be accounted for in this way, and are probably dependent on other causes, amongst which the low crasis of the blood is the most powerful. The treatment of pyemia is of the most unsatisfactory character. It doubt- less happens that patients occasionally recover from this disease, but such a result must be looked upon as a happy exception to its commonly fatal termi- nation. The only plan of treatment that holds out any reasonable hope of success, appears to me to be the stimulating and tonic one. I have certainly 6een service done, in some cases, and indeed recovery effected, by the adminis- tration of large doses of quinine, as much as five grains being given every third or fourth hour, with the best effect. A very serious case of pyemia, lately under my care at the hospital, occurring after amputation of the arm, and accompanied not only by all the symptoms of that disease in a very marked manner, but by pleuritic effusion, swelling and tenderness over one hip, and secondary hemorrhage from the stump, got well by perseverance in the tonic and stimulating plan of treatment. If the depression is very great, the car- bonate of ammonia in ten or fifteen grain doses may be given from time to time; such nourishment as the patient will take, with a liberal allowance of dietetio stimulants, being also administered. In the case of a superficial vein being inflamed, it has been recommended by TUMORS. 387 some of the French surgeons, as Bonnet, Berard, and Laugier, that the actual cautery should be freely applied along the course of the vessel, and they state that the best results have followed this practice. As abscesses form, they must be freely opened; and the diffuse and purulent collections forming in the cellular tissue must be evacuated. CHAPTER XXIX. TUMORS.1 The frequency with which tumors fall under the observation of the surgeon, the great variety in their characters, and their important relations, local as well as constitutional, render their consideration one of great moment. Accord- ing to Hunter, a tumor is "a circumscribed substance produced by disease, and different in its nature and consistence from the surrounding parts." This definition, though not perhaps accurately correct in some forms of tumor, which do not differ in their nature from neighboring parts, is yet substantially a good and convenient one. By a tumor may also be said to be meant a circumscribed mass, growing in some tissue or organ of the body, and dependent on a morbid excess or deviation of the nutrition of the part. The tumor thus formed in- creases in size by an inherent force of its own, irrespective of the growth of the rest of the system, and differs essentially from the normal structure and appearance of the part of the body in which it grows. In order to constitute a tumor, it is necessary that the normal form of the part be widely departed from — a mere increase in its size, so long as it preserves its usual shape, being scarcely considered in this light. Thus, if the tibia be uniformly enlarged to double its natural size, it would be said to constitute a hypertrophy, not a tumor; but, if a comparatively small rounded mass of bone project directly forwards from its tuberosity, it would be said to be a tumor, and not a mere hypertrophy. Surgeons divide tumors into two great classes, the non-malignant and the malignant. This division, though practically convenient, is not scientifically exact. Recent researches have shown that, although some tumors, as the cancers, are always and essentially malignant, and others as uniformly benign, as lipomas and some cysts, yet that many others that are usually innocent may, under certain conditions, at present unknown, take on a truly malignant action : this has led to the establishment of an intermediate group, that may be termed the semi-malignant. The non-malignant, innocent, or benign tumors are strictly local. They resemble more or less completely the normal textures of a part, and hence are very commonly, though not perhaps with strict propriety, termed homomor- phous. They usually grow slowly, are more or less distinctly circumscribed, being often enclosed in a cyst, and have no tendency to involve neighboring structures in their own growth; any change that they induce in contiguous parts being not by the degeneration or conversion of these into their own structures, but simply by the effects produced by their size and pressure dis- placing or atrophying them. They are sometimes single, but not unfrequently multiple, developing either simultaneously or successively; but if in the latter 1 In Paget's Lectures on Surgical Pathology, vol. ii. will be found the most philosophical account of tumors in this or any other language. 3S8 TUMORS. mode, without any connection with preceding growths. If removed by ope- ration, they do not return ; but if left to the natural processes of nature, they may slowly attain a great size, remain stationary, and at last atrophy, decay, or necrose. The essentially Malignant tumors differ widely from those last described. They cannot be considered as strictly local diseases, as in many cases they result primarily from a constitutional vice, or if local in the first instance, have a ten- dency rapidly to affect the constitution. They are essentially characterized by an extreme vegetative luxuriance and an exuberant vitality. They proceed from a germ which, in a manner at present unknown to us, is formed in some organ "or tissue, where it develops by an inherent force of its own, irrespective of neighboring parts, producing a mass which differs entirely in structure and appearance from anything observed in the normal condition of the body; and hence, not unfrequently called heteromorphous. This term, however, cannot be considered strictly accurate, inasmuch as the microscopic elements of which this mass are composed have their several analogues in the normal structures of the body. This mass, which may either be infiltrated in the tissues, or localized by being confined to a cyst, increases quickly in size; not uncommonly indeed the rapidity of the growth may be taken as a measure of the malignancy of the tumor. As it increases in size, it tends to implicate the neighboring structures in its own growth, and to affect distant organs through the medium of the lym- phatics or the blood; if removed by operation it has a great tendency, under certain conditions, local and constitutional, to return in its original site or else- where, though it does not necessarily do so. If left to its own development, a malignant tumor will inevitably soften, necrose, and ulcerate, often with much pain, profuse hemorrhage, and the induction of a peculiar state of constitutional cachexy, which speedily and necessarily terminates in death. Interposed between these two classes, we find a third group that partakes more or less of the characters of both; these may be termed semi-malignant tumors. The malignant tumors are usually of a cancerous nature, but " malignant" and "cancerous" are not synonymous. Every malignant tumor is not a cancer, though every cancer is a malignant growth. Some tumors are malignant in their course, though they present neither to the naked eye nor to the microscope any cancer structure or any heteromorphous constituent, but are strictly homo- morphous, being fibrous, fibro-plastic, or cartilaginous. In most instances such tumors are benign in their course as well as in their structure, but in other cases, and without any evident cause, they affect a truly malignant action; thus the term malignant would have reference rather to the course adopted by the tumor than to the structure of the growth itself, for a tumor maybe anatomically benign, but functionally malignant. Paget has very fully described varieties of the fibro-plastic as well as of the fibrous and cartilaginous tumor, which though preserving throughout a uniform character, microscopical and otherwise, that is not considered malignant, have nevertheless destroyed the patient by repeated recurrence after removal, and by ultimate ulceration, sloughing, and contamina- tion of neighboring tissues, or even of distant organs through the medium of the circulation. He makes the important observation that in different persons and under different conditions the same disease may pursue very opposite courses, appearing in some to be of an innocent, in others of a malignant type; and he makes the very interesting practical remark, which agrees entirely with the result of my own observation, that the children of cancerous parents may be the sub- ject of tumors apparently innocent in structure, but certainly resembling malig- nant growths in the rapidity of their progress, their liability to ulcerate and to bleed, and their great disposition to return after removal. Innocent and malignant tumors are occasionally met with in the same person, four or five different kinds of growth even occurring in one individual. I have INNOCENT TUMORS. 389 seen in one patient a scirrhous breast, an enchondromatous tumor of the leg, and atheromatous cyst on the back, with scrofulous glands in the neck. Ma- lignant and benign formations may even be found in the same mass; thus ence- phaloid and enchondroma are not unfrequently met with together in the testis. This, however, must not be taken as any evidence of the possibility of the con- version of one into the other, and indeed there is no proof that a non-malignant can be converted under any circumstances into a malignant tumor of a different type; a fibrous growth may degenerate and assume all the character of malig- nancy, at last destroying the patient, but there is no evidence that it can ever be changed into a cancerous mass. A malignant tumor may, however, be depo- sited on the site of a non-malignant growth that has been removed : thus I have seen a scirrhous nodule deposited in the cicatrix left after the removal of a cystic sarcoma of the breast. Beside these various forms of tumors, others are met with of a constitutional and specific character, such as those that occur in scrofula and syphilis. NON-MALIGNANT, OR INNOCENT TUMORS. The innocent tumors may, I think, be most conveniently arranged in three great classes. 1st. Encysted tumors of all kinds. 2d. Tumors dependent on the simple increase of size of already existing structures, in the tissues or organs in which they occur; as, for instance, fatty tumor in adipose tissues, exostosis in connection with bone, &c. 3d. Tumors dependent on the new growth of already existing structures, in situations where they are not normally found; as, for instance, a carti- laginous tumor in the midst of cellular tissue, or a fibrous tumor under a serous membrane. I.—E NCT8TED TUMORS Encysted tumors arrange themselves into two great classes. 1st. Those that are dependent upon the gradual accumulation of a secretion in a naturally existing duct or cyst, with dilatation and hypertrophy of its walls: 2d. Those that result from the new formation of a closed cyst in the cellular tissue of the part, and the distension of it by the secretion from its lining membrane. 1st. The encysted tumors arising from simple distension and gradual hyper- trophy of the walls of a duct or cyst are met with in three forms, (a) As encysted tumors of the skin and subjacent cellular tissue occurring in various parts of the body, and dependent on the closure of the excretory ducts of the sebaceous glands: (p) As formed by the accumulation of secretions in, and the closure and dilatation of, the ducts of other secreting glands and organs, as in the sublingual or mammary gland: (y) Those formed by the retention and modification of the secretions in cysts without excretory ducts, as in the bursae. (a) Encysted tumors occurring from the obstruction of the excretory duct of the sebaceous glands, include the various forms of atheromatous tumors that are met with on the surface of the body. These are usually situated upon the scalp, face, neck, or back; sometimes, however, they occur elsewhere ;—thus I have removed a very large one from the forepart of a girl's arm, and others from the labia and groin. In size these tumors vary from that of a pin's head to an orange; the smallest occur on the eyelids, the largest on the shoulders and scalp. They are often very numerous, especially about the head, where as many as thirty or forty may be met with at the same time; and most frequently they form in women about the middle period of life: they are smooth, round, or oval, movable under the integument, either semi-fluctuating or elastic, though sometimes solid to the touch. In some parts where the sebaceous follicles are 390 INNOCENT TUMORS, Fio. 141. large, as on the back, a small black point can often be detected on the surface of the tumor, through which an aperture may be found leading into its interior, and admitting the expulsion of its contents. In structure they are composed of a cyst which varies greatly in thickness, being sometimes thin, filamentous and soft; at others so thick, hard, laminated, and elastic, that it is almost impos- sible not to believe it to be a new formation; these cysts attain their greatest density on the scalp, and are here often very firm, elastic, and resisting, even though of but small size. In structure they are composed of cellulo-fibrous tissue, with an epithelial lining, and generally appear to be a dilated and hyper- trophied state of the sebaceous follicles, though not improbably, as Paget sup- poses, they may at times be new formations. They are usually attached by loose and lax cellular tissue to the subjacent parts; but, if thin, are often pretty closely incorporated with the super-imposed skin; if inflammation is set up around them they become more solidly fixed. The contents of these cysts are very various, most usually consisting of a soft, creamy, pultaceous, or cheesy-looking mass, of a yellowish-white color, which has sometimes in old cysts become dry and laminated, looking not unlike parmesan. In others, again, of old standing and large size, the contents may be found to be semi-fluid, the more liquid parts being of a brown, green, or blackish tint. These various contents are essentially composed of modified sebaceous secretion, such as epithelial scales, fat granules, cholesterine, granular matter, and rudi- mentary hairs in various proportions (fig. 141). The growth of these tumors is often very slow, but not unfrequently after remaining stationary for years, they take on a rather rapid increase. The tumor itself, though painless, may give rise to uneasy sensations by compressing nerves in its vicinity; it usually continues to grow slowly until the patient being annoyed by its presence, gets it removed by operation. If left untouched, it occasionally, though rarely happens, that the sebaceons matter exuding through an aperture on its surface forms a kind of scab or crust, which by a process of sub-deposition becomes conical; and being gradually pushed up from below, at the same time that it assumes by exposure a dark brown color, forms an excrescence that looks like a horn, and is usually considered to be of that character (fig. 142). These " horns" have been met with on the head, on the buttock, and occasionally in other situations, and have been well described by Mr. Eras- mus Wilson; some time ago a woman applied to me with one about an inch and a half long growing from the upper lip. In other cases again, these tumors inflame and suppurate; the skin covering them becomes adherent and reddened, ulceration takes place, and if the cyst be small and dense, it may be thrown off by the suppurative action in the surround- ing tissues. If of larger size, ulceration of the integuments covering it takes place, and the sebaceous matter is exposed; this may then putrefy, become offensive, and break away in unhealthy suppuration. In other cases again, peculiar changes take place in this tissue, large granulations are thrown out in it, and the atheromatous mass appears to vascularize, becoming irregular and nodulated, rising up in tuberous growths with everted edges, exuding a fetid, foul discharge, becoming adherent to subjacent parts, and assuming a senii-ma- Fig. 142. CYSTIC TUMORS. 391 lignant appearance, forming at last a sore perhaps as large as a saucer, as in the annexed figure of a case sent to me by Dr. Bryant (fig. 143). Sebaceous cysts which have undergone this change may however readily be distinguished from such malignant growths by a microscopical examination of their exudation or debris, these consisting of pus and healthy epithelium, mixed up with fatty matters more or less disintegrated. The only diseases with which these tumors can be confounded are abscesses and fatty growths. From an abscess an encysted seba- ceous tumor may be distinguished by its history, slow growth, situation, elasticity, and mobility, and the existence of the dilated orifice of the sebaceous duct, through which some of the contents can be squeezed, the microscopical examination of which will serve to confirm the diagnosis. From a fatty tumor these growths may be diagnosed by their firmer and more regular feel, and in case of doubt by the evacuation and examination of their contents. The treatment of a tumor of this kind simply consists in its removal, after which it is never reproduced. This may most readily be done by transfixing and cutting it across with the scalpel or bistoury, and then seizing the side of its cut edge with a pair of forceps, pulling the cyst out of its loose cellular bed. This plan may commonly be adopted with those seated about the head, face, or neck. When about the back, trunk, or limbs, they usually require to be dis- sected out, being more closely incorporated with the skin, and often adherent by former inflammation to the subjacent parts. In doing this, care should be taken that the whole of the cyst is extirpated; the wound that is left should then be dressed lightly, and speedily heals. If, however, any portion of the cyst be left behind, a troublesome fistula may remain. When occurring upon the scalp, a large number of these tumors may be removed at one sitting; as, however, there is always some danger of erysipelas following operations in this situation, it is only prudent to select a favorable season of the year, and not to operate if the tumor be in any way irritated at the time, or the health out of order. Erysipelas is especially apt to occur after these operations in elderly people of a stout make and florid complexion. The horns and semi-malignant ulcers that result from these growths may require excision. If, however, the ulceration be connected with the cranium by its base, or be very extensive, as in the case depicted above (fig. 143), it will be safer to treat it by the application of a weak solution of the chloride of zinc, or by occasionally touching it with fused potass. (0) Various forms of encysted tumor may arise from the closure and dila- tation of the ducts of other excretory organs; as, for instance ranula by the occlusion of the salivary ducts, encysted hydrocele by the closure of the tubuli testis, or cystic tumors of the breast by the obstruction of the lacteal ducts. These affections, however, constitute special diseases, the consideration of which must be deferred to subsequent chapters. The general principle of treatment in these kinds of affection, consists either in restoring the freedom of the outlet by the excision of a portion of the wall, or obliterating the cyst by making an incision into it, and allowing it to granulate from the bottom. (y) Cysts may arise by the distension of cavities which are unprovided with any excretory duct; as for instance the bursae which often attain a very con- siderable size under these circumstances. The structure of these cysts becomes greatly altered; sometimes the walls are thin and expanded; at others they 392 INNOCENT TUMORS. acquire a thick cellulo-fibrous, almost ligamentous, appearance. Inside they are often warty-looking, from the deposition of imperfectly-organized fibrine, often arranged in a laminated form. Not unfrequently attached to the walls, and floating in the interior, are a number of granular, melon-seed-like bodies, greyish or yellow in color, semi-transparent, elongated or irregular in shape, usually rather hard, but sometimes soft and flocculent. These appear to be composed of masses of imperfectly-organized fibrine, somewhat resembling in structure granulation-cells, and often form in large quantities, so as to block up the interi6r of the cyst, converting it into a solid tumor. The fluid contents of these cysts are usually thin and serous, of a yellowish or brownish color. In their progress these cysts are found to increase up to a certain size, when they usually thicken and harden, in consequence of the fibrinous trans- formation just described; or else inflame and suppurate in an unhealthy manner. They may occur in any of the situations in which bursae naturally exist or are accidentally formed, and which will be mentioned hereafter, but are most commonly met with upon the knee cap, the nates, or the first joint of the great toe. The treatment of these cysts consists in attempting their absorption by the use of stimulating plasters; or, if this fail, in the removal of their contents by tapping. Their cavities are then closed by exciting inflammation and suppu- ration within them, by the introduction of a seton, by injection with stimu- lating solutions, or by the subcutaneous section. If these means fail, excision will be required, more especially if the tumor have assumed a dense and fibrous character. 2d. Cysts occasionally are met with as new formations, filling by their own secretion. They occur in the general cellular tissue, and in connection with the sheaths of tendons, but most frequently about the generative organs, more especially in the ovary, in the broad ligament of the uterus, or in the breast. These cysts vary most widely in size, from that of a millet-seed to tumors weighing many pounds, and filling up the greater part of the abdominal cavity. When small, they are usually thin-walled, and are often imbedded in a matrix composed of imperfect hypertrophy of the organ in which they are situated, as in the breast and testes; when large, as in the ovary, the walls are thick, firm, satiny, and often very tough. Projecting into their interior are solid masses, consisting of cauliflower-like growths, occasionally filling up the whole inside of the cyst with compact solid white layers. These " intracystic" growths cause by their increase in size the gradual absorption of the more fluid contents, until, at last, their development is arrested by the cyst wall. These cysts may be divided into the simple and the compound. The simple, or, as they are commonly called, serous cysts, are met with in almost every situation, being composed of a thin expanded wall, containing a slightly viscid, 6erous fluid. The compound, or, as they are often called, proliferous or multilocular cysts, are especially met with in the ovary, and have been studied with great care by Hodgkin. Of these there are two varieties, the first consisting of an aggre- gation of simple cysts closely packed and pressed together; the second composed of cysts having others growing from their walls. The cavities of these multi- locular cysts present the greatest possible variety in their contents; fluid, from a limpid serum to a semi-solid jelly-like matter, and of every shade, from light- yellow to greenish-black, or dark-brown, is met with in them; solid intracystic growths, cancerous masses, or the debris of epithelial and cutaneous structures are also found in them. Encysted tumors containing hair and fatty matters (pilocystic tumors), are occasionally met with. These would, in many instances, appear to be the remains of a blighted ovum inclosed in the body, as they are congenital, and usually contain some foetal debris, such as portions of bone, teeth, &c. The WARTS. — SARCOMA. — POLYPI. 393 hairs in these tumors are connected with, and grow from, cuticular structures in which sebaceous follicles are commonly distinctly observable. The fatty master which they contain in large quantity, and which may either be solid or perfectly fluid, is in all probability the result of fatty degeneration of the soft tissues of which they are composed. These tumors are most frequently met with in the abdomen, especially about the ovaries, mesentery, and omentum ; they have also been observed in connection with the testes, having probably descended into the scrotum with this gland. A very remarkable case of this kind lately occurred at the University College Hospital under Mr. Marshall. They have also been found about the face, but never, I believe, in connection with the thoracic cavity or extremities. The sanguineous cyst, or hsematoma, is a peculiar variety of the simple form, and has been described by Paget as especially occurring about the neck, the parotid, the anterior part of the thigh, the leg, the shoulder, and the pubes. It is especially characterized by containing fluid blood, more or less altered in appearance. He describes these cysts as being formed in three different ways: either by hemorrhage into a previously existing serous cyst, by transformation from a naevus, or by a vein becoming occluded and dilating into a cyst. These sanguineous cysts may sometimes resemble in general appearance encephaloid disease. A case of this kind was sent to me by my friend, Dr. Henry Bennet —a tumor about the size of an orange, of nodulated appearance, existing in the leg of a woman below the knee, where it had been gradually increasing in size for about a couple of years. So close was the resemblance to malignant disease presented by the tumor, that the limb had been condemned for amputation by some surgeons who had previously seen the case; as, however, the growth, on examination, turned out to be a sanguineous cyst, as its walls were thin and adherent, and as it extended too deeply into the ham to admit of ready removal, I reduced it by successive tappings, and then laying it open, allowed it to granulate from the bottom. When practicable, however, the cyst should always be dissected out. II. — TUMORS ARISING FROM SIMPLE INCREASE OF SIZE OF ALREADY EXISTING TISSUES. These tumors differ from simple hypertrophy of the part " in this, that to whatever extent the hypertrophy may proceed, the overgrown part always main- tains itself in normal type of shape and structure, while a tumor is essentially a deviation from the normal type of the body in which it grows." (Paget). This section comprises, 1st, tumors connected with the integumental struc- tures, as warts, polypi, &c.; 2d, lobular hypertrophies, with more or less modi- fication of glandular structure, as in the breast; 3d, fatty tumors; 4th, vascular tumors; 5th, tumors of nerves; and 6th, tumors of bones. 1st. Simple tumors of this kind that develop on the integumental structures, whether cutaneous or mucous, are warts and condylomata. These essentially consist in an increased deposit of laminated cuticle, usually with some augmented vascularity of the cutis. They exist with especial frequency in the mucous, the muco-cutaneous, and the more perspirable surfaces; thus the prepuce, the vagina, the axilla, and the cleft of the nates are their chosen seats. When oc- curring on the skin, they are usually hard and horny where the cuticle is natu- rally dry, and then constitute true warts; but where the skin is perspirable, and the cuticle moist, they are flattened, expanded, soft, and white, and are then termed condylomata or mucous tubercles. When situated on the mucous mem- branes, they are usually pointed, somewhat pendulous, or nodulated on the surface, very vascular, and bleed readily when touched. Closely allied to some of these warty structures is a peculiar pinkish-white fibro-vascular tissue, which is occasionally met with in old cicatrices as an out- 394 INNOCENT TUMORS. growth of these, and not unfrequently recurs after removal; this disease is termed cheloid. The general principles of treatment of these affections consist in their removal by excision, ligature, or caustics, according to their size, situation, and attach- ments. Excision is usually preferable when they are seated on mucous sur- faces ; the ligatures should be used if they are large and pendulous, and caustics should be employed when they are seated on the skin or a muco-cutaneous surface. Pendulous sarcomatous growths, forming large tumors commonly called "wens," may occur on any part of the surface. They are smooth, pedunculated, firm, somewhat doughy, but non-elastic, pendulous, and movable, slowly increasing without pain, often to a very great size. It is in warm climates, and in the Hindoo and Negro races, that they attain their greatest development, having been met with fifty, seventy, and even a hundred pounds in weight. They are chiefly seated about the genital organs, enveloping the scrotum, penis, and testes in the male, or depending from the labia of the female. That remarkable enlargement of the leg occurring in the Mauritius, and some parts of the West Indies, and hence termed Barbadoes leg, is an affection of this kind. In struc- ture these growths appear to be a simple hypertrophy of the fibro-cellular element of the part affected, being composed of a loose reddish stroma, moist with a serous fluid. In the treatment of these affections, pressure and iodine applications may be tried in the earlier stages, with the view, if possible, of checking their growth; at a later period they must, if large, be removed by operation, though this procedure is at times an extremely severe one, owing to the great magnitude they attain. Polypi are pendulous masses growing from any mucous surface, but more espe- cially from the nose, ear, throat, uterus, and rectum. The term polypus is applied very indiscriminately to various pendulous tumors growing from mucous membranes. The true mucous or gelatinous polyp is composed of the elements of this membrane expanded and spread out, and consists of a loose fibrous stroma covered by epithelium more or less distinctly ciliated, the cilia being often beau- tifully seen when recent specimens are examined under the microscope. The so-called fibrous or medullary polyp consists of other forms of tumor growing from, and covered by, mucous membrane. The true mucous polyp grows rapidly, being a soft and vascular reddish-purple or brown-looking mass, and may expand greatly, giving rise to serious symptoms of obstruction in the passage in which it is situate, bleeding freely when touched, destroying the bones by its pressure, and producing great mischief and disfigurement. It is especially in the nose and uterus that it attains to a large and dangerous size. The treatment consists in removing it according to its situation, its degree of vascularity, and the nature of its attachment, by avulsion, ligature, or excision. 2d. Hypertrophy of glandular structures. — This forms an important series of special affections, chiefly occurring in the lymphatic glands, the breast, and the testes. The parts becomes chronically enlarged and indurated, often with- out any signs of inflammatory action, though in other cases as the result of this condition. On examination, the structure of the gland will either be found to have undergone an imperfect and ill-developed hypertrophy in some of its lobules, or to be expanded and infiltrated with plastic matter, the consequence of chronic inflammation; or else to have undergone tuberculous deposition when occurring in strumous subjects. The principle of treatment in these tumors consists in an endeavor to remove the mass by frictions with the preparations of iodine, or by the application of stimulating and absorbent plasters. If these means fail, methodical pressure may sometimes advantageously be employed, and, as a last resource, extirpation by the knife. 3d. Fatty tume>rs constitute an important class of surgical diseases, as they occur very extensively in almost every part of the body, and at all ages, though FATTY AND FIBRO-CELLULAR TUMORS. 395 they are most commonly met with about the earlier periods of middle life. In the majority of cases they appear to originate without any evident cause; in other instances again they can be distinctly traced to pressure or to some local irritation, as to that of braces or shoulder-straps over the back and shoulders. In one case I have known the disease to be hereditarily transmitted to the members of three generations of a family. Fatty accumulations take place under two forms, one diffused, the other cir- cumscribed ; it is only the latter variety that is termed the adipose tumor. The diffused form of fatty deposition occurs in masses about the chin or nates with- out constituting a disease, though it may occasion much disfigurement. Fatty or adipose tumors may form in all parts of the body as soft, indolent, inelastic, and doughy swellings, growing but very slowly; being either oval or round, but not unfrequently lobulated, and occurring most frequently in the subcutaneous fat about the neck and shoulders; but occasionally met with between the muscles, in the neighborhood of joints, of serous membranes, as of the pleura, and of mucous canals. A very curious circumstance connected with these tumors is that they occasionally shift their seat, slowly gliding for some distance from the original spot on which they grew; thus, Paget relates cases in which fatty tumors shifted their position from the groin to the peri- neum or the thigh. I have known one descend from the shoulder on to the breast. They may attain a large size, but only occasion inconvenience by their pres- sure or bulk; they rarely ulcerate or inflame, nor do they undergo any ulterior changes of structure. These fatty growths have been divided into three varieties, according to their structural differences. The most common form of fatty tumor, that called lipetma, is a mass of yellow, oily, fatty matter and cellular tissue, inclosed in a fine thin capsule, having small vessels ramifying over its surface. This tumor is usually more or less lobulated, often remarkably dentated, and sending out irregular prolongations that extend to some little distance into the surrounding cellulo-adipose tissue. Another variety, the cholesteatoma of Muller, is of much less frequent occurrence; it is a smooth, laminated, white and dry fatty mass, contained in a cyst, and apparently composed of crystalline fat inclosed in meshes of cellular tissue. The third variety of fatty tumor consists of masses occurring in the ovary, or in multilocular cysts in other situations. In the treatment of fatty tumors little can be done except by extirpation with the knife, by which the patient is speedily and effectually ridded of the disease. The tumor being encapsuled and but loosely adherent to adjacent parts, readily turns out and the wound often heals by the first intention. It is true that we have the sanction of Sir B. Brodie's high authority for the administration of the liquor potassae in some of these cases, under which treatment this eminent surgeon states that fatty tumors have occasionally disappeared. Fibro-cellular tumor. — This growth, described cursorily by many writers as the cellular tumor, has been more fully examined by Paget. It is not of com- mon occurrence, and when met with it is most frequently found in the scrotum, the labium, the deep muscular interspaces of the thigh, and on the scalp, in which situations it may form tolerable large masses, attaining sometimes to a weight of many pounds. When occurring about the scrotum and labium, these tumors must not be confounded with elephantiasis of these parts, from which they may be distinguished by being limited and circumscribed masses, and not mere outgrowths. They happen only in adults who otherwise are in good health, and grow quickly, forming soft, elastic, rounded, and smooth tumors; they are not attended by any pain. After removal they are found to possess a thin capsule, to be of a yellowish color, and to contain a large quantity of infiltrated serous fluid, which may be squeezed out abundantly. As these 396 INNOCENT TUMORS. tumors are of a perfectly innocent character, no hesitation need be entertained about their removal. 4th. Tumors dependent on an increase of the vascular tissue, as aneurism by anastomosis, — of the nervous tissue, as some kinds of neuromata, — and of osseous tissue as exostoses, and never extending beyond the structure primarily implicated, constitute such special affections, that it will be more convenient to reserve their consideration until we come to speak of the particular diseases of the structures to which they belong; and it will be sufficient for the present to indicate their existence as pertaining to this group. III. — TUMORS DEPENDING ON THE NEW GROWTH OF STRUCTURES IDENTICAL WITH, OR VERY CLOSELY RESEMBLING, NORMAL TISSUES IN SITUATIONS WHERE TUEY ARE NOT NORMALLY FOUND. This class is an important one, inasmuch as it contains not only innocent growths, but some that are of a semi-malignant character. The fibrous, the fibro-plastic, and the enchondromatous tumors are those that are chiefly met with in it. 1st. Fibrous tumors. — These growths are by no means so common as many of the affections that have already been described; they are met with in various situations, as in the testes and mamma, uterus and antrum, about joints, in the periosteum, in the subcutaneous cellular tissue, and in connection with nerves. The situations in which they are most frequent, and where their structure is and this is the condition in which they are often presented to the surgeon. Eventually, however, they are apt to undergo disintegration, becoming infiltrated, cedematous, and softening in the centre, or at various points of the circumference; they then break down into a semi-fluid mass, the integuments covering them inflame, slough, and an unhealthy suppuration mixed with disorganized portions of the tumor is poured out, leaving a large and unhealthy slough chasm from which fungous sprouts may shoot up: readily bleeding on the slightest touch and giving the part a malig- nant appearance; the patient eventually falling into a cachectic condition, and becoming exhausted by the hemorrhage and discharges. In other cases again, these tumors may degenerate into a spongy calcareous mass of a brownish color and hard consistence; but they never undergo proper ossification. More rarely SEMI-MALIGNANT TUMORS. 397 the interior of these growths softens and undergoes absorption, so as occasionally to form cysts of large size, containing fluids of various shades of color. Paget relates the case of a very large cyst of this kind formed by the hollowing out of a fibrous tumor of the uterus being twice tapped by mistake for ovarian dropsy. The treatment of these tumors is in a great measure palliative, but when so situated as to admit of removal, as in the neck, under the angle of the jaw, or in the antrum, they should always be extirpated. 2d. The next class of tumors, though closely resembling the fibroid in struc- ture, have a great tendency to recur after removal, to disintegrate and contami- nate neighboring parts and even the system at large. They are in their appear- ance innocent, but in their course malignant. This class comprises the so-called semi-malignant tumors, viz., the malignant fibrous, the recurring fibroid, the fibro-plastic, and the enchondromatous tumors. The malignant fibrous tumor closely resembles in its general appearance and microscopic elements the ordinary fibrous growths, but its great characteristic is its recurrence after removal, with much tendency to ulceration, sloughing, and hemorrhage, forming not only in its original locality, but in internal parts of the body at a distance from it. The fibroplastic or myeloid tumor was first described by Lebert, and has been investigated by Paget, who finds it to stand intermediate in structure between the fibrous and fibro-cellular, resembling pretty closely that of granu- lation-cells in the process of development into fibro-cellular tissue, having parallel fibres with wide fibro-plastic cells, and occasional oat-shaped nuclei. It is found about the jaws, in the bones, in the cellular tissue of the neck, and in the mammary gland. These tumors, the albuminous sarcoma of Abernethy, present marked cha- racters. On making a section of them they cut in a uniform, smooth, and somewhat elastic manner; are semi-transparent, shiny, and juicy-looking, of a greenish-grey, bluish or pinkish color, often spotted or stained with dis- colored marks, varying in tint from a blood to a pinkish, brownish, or livid red hue, which, if extensive, gives them a fleshy look; their structure is usually brittle. They most commonly occur in young people, without pain and without any known cause. In the majority of cases they may be safely removed with- out the prospect of recurrence, but occasionally, and without any apparent reason, they return after removal. Lebert relates six cases of this disease in which recurrence took place after operation, with secondary deposits in internal organs. The recurring fibroid tumor has been described by Paget as closely resem- bling in general aspect the common fibrous tumor, whilst in its microscopic structure it is very like the fibro-plastic tumor, its most marked character being its tendency to recur after removal. Of this peculiar and hitherto undescribed disease, he relates two cases, one a tumor of the upper part of the leg, which, between 1846 and the end of 1848; had been removed five times, re-appearing for the sixth time after the last operation, when, attaining a large size, and becoming ulcerated, amputation was deemed advisable; this operation, how- ever, was followed by death. The examination of this tumor presented " very narrow, elongated, caudate, and oat-shaped nucleated cells, many of which had long and subdivided terminal processes." In the second case, a tumor of the shoulder had been removed, and returned four times between May, 1848, and December, 1849, re-appearing in the following year for the fifth time, the patient, notwithstanding, appearing at this period to be a strong and healthy man. He also relates a case by Gluge, in which a similar tumor was five times removed from the scapula, its sixth re-appearance being followed by death. The most interesting of all, perhaps, is a case by Dr. Maclagan, in which, after three removals, no further recurrence of the disease took place. It is a remarkable circumstance that these recurrent tumors appear, according to Paget, to become 398 INNOCENT TUMORS. more malignant in their growth in the later than in the earlier recurrences, ac- quiring more and more the characters of true malignant disease, becoming more painful, rapidly degenerating, and giving rise to an ulcerating fungus, which eventually proves fatal by exhaustion and hemorrhage. 3d. Enchondroma, or the cartilaginous tumor, carefully studied by Miiller, and investigated by Paget, is an exceedingly interesting affection, whether we regard the peculiarity of its structure, its comparatively frequent occurrence, or the large size that it occasionally assumes. It takes place under two distinct forms; most commonly as an innocent growth, but in other cases assuming a malignant tendency and appearance. These two forms present different signs; in the first case, the echondroma occurs as a hard, smooth, elastic, ovoid, round, or flattened tumor, of small, or but of moderate size, seldom exceeding that of an orange, and growing slowly without pain. In the second form, it approaches in its characters to malignant disease, growing with extreme rapidity, attaining an enormous size in a few months, and contaminating the system by the deposit of secondary echondromatous growths in internal organs; under these circum- stances, it would appear to have occasionally been mistaken for the rapidly spreading forms of encephaloid disease. But although occasionally assuming the course that is usually adopted by true malignant growths only, it must be borne in mind that enchondromata, especially of the testes, are not unfrequently associated with encephaloid; and when so, the secondary deposits are usually of the latter character only, although in some rare cases even these have been found of a mixed nature. When these growths attain a tolerably large size, though occasionally whilst they are still of but moderate dimensions, ossification may occur in some parts; whilst a process of disintegration may take place in others, they soften, break down, and liquefy in their interior, causing the skin which covers them to become duskily inflamed, eventually to slough, and to form fistulous openings, through which a thin jelly-like matter is discharged. In some cases it would appear that large tumors of this description, softening in the centre, and becoming elastic and semi-fluctuating, have been mistaken for cysts, and have been tapped on this supposition. In small enchondromata the opposite condition more frequently occurs, the tumor becoming indurated, and undergoing ossification. The accompanying cut is a good illustration of the microscopical characters of these tumors (fig. 145). It shows a clear matrix, in places thinly granular, in others slightly fibrous, imbedded in which are cells and nuclei of various forms and sizes, some round or irregularly oval, from 5«jo-th to gjjotii of an inch in diameter. Many are branched or caudate; some of the spheroidal cells are granular, others have nuclei of irregular outline; inter- spersed among them are a few oil globules. The general appearance is that of foetal cartilage, from which it can with difficulty be distinguished. Most frequently enchondroma occurs in connection with some of the short bones, more particularly those of the metacarpus and the phalanges of the fingers, presenting hard rounded knobs in these situations, where, however, it seldom attains a greater magnitude than a walnut or a pigeon's egg. When large, it is commonly met with in or upon the head of the tibia, or the condyles of the femur, forming in these situations rapidly increasing growths of consi- derable magnitude. It may also form in the parotid region, in the muscular ENCHONDROMA. — CANCER. 399 interspaces of the neck, thigh and leg, and in the testes. When connected with the bones, enchondroma may either spring from the periosteum, gradually en veloping, absorbing, and eventually destroy- ing, the osseous structures, though at first not incorporated with them. This is their usual mode of origin when occurring in the femur or tibia: when seated on the short bones, especially on the metacarpus and pha- langes (figs. 146, 147), they commonly spring from the interior of the osseous struc- ture, expanding, absorbing, and involving its walls in the general mass of the' tumor. When occurring in cellular regions uncon- nected with bone, the enchondroma is softer, and does not present such distinct cartilage cells as in the osseous enchondroma. Most frequently these enchondromatous masses occur in childhood, or shortly after puberty, appearing as it were to be an overgrowth of the cartilaginous element of the osseous system at this period of life. The treatment consists either in excision of the tumor, or amputation of the affected part. Excision may be practised when the tumor is seated in the parotid region, or otherwise uncon- nected with bone. When forming Fig. 147. a part of the osseous structures, it cannot well be got rid of without the removal of the bone that it im- plicates by amputation. If, under these circumstances, excision of the tumor only be attempted, it will be found that the whole mass cannot be removed, and that it rapidly grows again, or that the wound formed by the operation remains fistulous and open. Most com- monly a permanent cure is effected by the ablation of the tumor in one or other of these ways, but cases have occurred of the more rapidly growing form of the disease recurring, after its removal, in a softer state than before, and with a close approximation to malignancy in appearance and action. It is worthy of remark, as showing the connection between enchondroma and malig- nant disease, that cartilaginous masses have been met with in the midst of encephaloid tumors of the bones and testes. CANCER.1 Having now considered innocent tumors, that have no tendency to contami- nate neighboring structures, or to return after removal; and the semi-malignant, which, though innocent in structure, are malignant in their course, and, under 1 It is not my intention to enter largely into the general history of malignant diseases, as space will not admit of my doing so; I would therefore refer my readers who wish for further information on this interesting subject to the works of Abernethy; the papers by Lawrence; the admirable and magnificent " Illustrations of the Elementary Forms of Disease," by Sir R. Carswell; to the excellent and copious monograph by Dr. Walshe; and to Mr. Paget's philosophic Lectures on this subject. In these different sources will be found nearly all the information at present possessed by the profession on the import- ant and interesting subject of Cancer. Fig. 146. 400 CANCER. certain obscure conditions, local or constitutional, as yet undetermined, have a disposition to recur after operation; we next proceed 'to the study of that form of malignant growth which has, as it were, a natural and constant tendency to affect the system, to implicate neighboring structures, and to return in its ori- ginal site, or at a distance from it, after extirpation. Cancer differs from all normal structures by being distinctly and essentially a new product, never, under any circumstances, existing in a healthy system, and possessing vital properties and an organization that is peculiar to itself. Cancer presents itself in four if not five varieties, which differ so much from one another in appearance, in rapidity of growth, in consistence, color, and struc- ture, as at first sight almost to appear to constitute essentially different diseases, but yet having so close a family resemblance, and presenting so many points of identity, that, physiologically and pathologically speaking, they must be consi- dered as mere varieties of the same class of tumors. The varieties of cancer generally admitted are the scirrhus, or the hard cancer; encephaloid, or the soft cancer; colloid, or gelatinous cancer; melanosis, or the black cancer. We meet with cancer, in one or other of these forms, usually the encephaloid, associated with some of the normal constituents of the body. With cartilage, as chondroid; with bone, as osteoid; with an erectile vascular structure, as aneurismal; and with epithelial cells, as epithelial cancer. Other varieties of cancer are met with, deriving their distinctive characters from some pecu- liarity of structure. Thus, when cysts are largely developed in the substance or in the surface of the growth, we have cystic cancer; and when the surface assumes a dendritic and papillated character, the form of the disease is termed villous. These various forms of cancer differ from one another in appearance and consistence; the scirrhus being hard, firm, semi-transparent, of a bluish or greyish color; the encephaloid being brain-like in appearance, soft, and hemorrhagic; the colloid resembling glue, or honey in its comb; the melanosis being black, sometimes solid, at others liquid; and the epithelial form occur- ring as nodules or ulcers, presenting peculiar characters. They vary also in the rapidity of their growth, in their vascularity, and in the order of their malignancy, in all of which respects they may be arranged as follows: 1st. Encephaloid; 2d. Scirrhus; 3d. Melanosis; 4th. Colloid; 5th. Epithelial cancer. Great as the differences amongst them are, however, the points of resemblance are still more striking; thus, one form of cancer may take the place of another, or be associated with it; encephaloid occurring after the removal of scirrhus, or being associated with melanosis; or colloid and scirrhus being met with together in the same tumor. This identity of seat and of recurrence, which tends more than anything else to establish a common origin amongst these tumors, has been specially pointed out by Carswell. Then, again, these tumors are all of a truly malignant character, having a tendency to induce a peculiar and similar condition of system that goes by the name of the cancerous cachexy. In chemical composition, also, they are all very nearly identical, being princi- pally composed of albumen. The microscopic characters of the different forms of cancer have of late years attracted considerable attention amongst pathologists. They consist, in all the varieties, essentially of the same elements, though these may differ somewhat in appearance and in relative preponderance, in the different forms of the affection. In all there is a fibrous stroma or basis, firmer and closer in some, as in scirrhus, than in the others. This yields, by scraping or pressure, a turbid'fluid termed the cancer juice, in which granules, cells, pigmentary and fatty matters, are found in varying proportion. The granules, which are minute, sometimes amorphous, at others presenting that peculiar vibratory condition termed the molecular movement, are met with in all the varieties of cancer, VARIETIES OF CANCER. 401 though they occur in largest quantity in scirrhus. The cells to which great importance has been attached by various observers, and which have often been looked upon as characteristic, or pathognomonic, of the disease, though erro- neously so in the strict acceptation of the term, present, however, such peculiar characters, that it is almost impossible to mistake them. They are large, spherical, fusiform or spindle-shaped, elliptic or caudate, having often two or three terminations, are usually com- pound, granular, have large nuclei, and prominent, well-marked nucleoli (fig. 148). These various appearances are presented by them in all forms of the disease; it is, however, more especially in the encephaloid variety that they assume a large size, and present their most marked fusiform and caudate shapes (fig. 149). The pigmentary cells are principally, if not altogether, found in melanosis. Much diversity of opinion exists Cells from Scirrhus of Breast (rapidly recurring). amongst surgeons as to the value that should be attached to these microscopic signs in determining the true nature of many tumors; some being guided by these appearances alone, others looking upon them as uncertain and fallacious, and trusting rather to the general cha- racters of the growth. The latter, however, appears to me to be too limited a view of the subject, for although the unaided eye of an experienced surgeon may in many cases recog- nize the true character of a tumor, and the mi- croscope in some few in- stances fail to reveal it, yet there can be no doubt that, in many cases, it is only by the aid of this instrument that the real nature of the growth can be determined. It is doubtless true that every one of these mi- croscopic elements may separately occur in the normal tissues and secre- tions of the body, some in those of the adult, others, as the caudate and fusiform corpuscles, in the embryo; but though this be the case, it does not appear that they are Fig. 149. Cells from Encephaloid of Tongue (rapidly growing). ever found in any tumors except those of a cancerous nature; and in these it is rather by the aggregation of these appearances, than by any single one in particular, that the true character of the disease is determined. In these exa- minations, however, the experienced surgeon will find that the appearances presented to the naked eye will assist him much in pronouncing upon the malignant or cancerous character of the tumor. It is certainly a remarkable 26 402 CANCER. circumstance, that the "recurring," or semi-malignant diseases, as well as those that are truly cancerous or positively malignant, present, under the microscope, structures that closely resemble those of tissues in process of development, either in form of imperfect exudative matter and fibro-cellular tissue, as in the fibro-plastic tumors, or in the similarity presented by the corpuscles of encepha- loid to some of those of the soft tissues in the embryo. The general characters that attend the progress of these several forms of cancer present numerous points of resemblance. When once formed, the tumor continues progressively to increase in size with a degree of rapidity, and to an extent, that varies according to its kind; the scirrhous tumors growing most slowly, and attaining but moderate dimensions; the encepha- loid and colloid often with great rapidity, and to an immense size. When the full growth of the tumor is attained, the process of decay commences. The mass softens at some point, the skin covering which becomes duskily inflamed and ulcerated, an irregular sloughy aperture forming, through which the debris of the mass are eliminated in an ichorous or sanious fluid, having often a peculiar fetid smell. The ulcer then pretty rapidly increases, with everted edges, a hard and knobby or soft and fungating surface, and the discharge of a dark fluid, often attended by hemorrhage, and occasionally with sloughing of portions of the mass. Coincident with the implication and ulceration of the skin, there is usually deposit in the lymphatic glands, with great increase of pain, and most commonly with the supervention of the constitutional cachexy; though in some cases this condition precedes the cutaneous impli- cation. This cachexy appears to be the result of the admixture of cancer germs with the blood, and their circulation through the body; or to some other modification in the condition of the blood, induced by the action of this growth on the economy. The exhaustion resulting from the ulceration, sloughing, and consecutive hemorrhage, also commonly increases this cachectic state; in many instances it is not marked until after the skin has become affected, and in others it does not supervene until ulceration is actually set up. In this cachexy the countenance is peculiarly pale, drawn, and sallow, so that the patient has a very anxious and care-worn look. The general surface of the body commonly acquires an earthy or yellowish tint, and not unfrequently large spots of pityriasis or chloasma make their appearance on various parts of it; the appetite is impaired, the voice enfeebled, the muscular strength greatly diminished, and the pulse weak. The patient complains of pains in the limbs, of lassitude, and of inability for exertion; he emaciates rapidly, and frequently suffers by the occurrence of cancerous deposits in internal organs; and at last dies from exhaustion, induced by the conjoined effects of weakening discharges, general debility, and pain. These general characters, however, present certain varieties of importance, according to the form of cancer that is developed. The scirrhus, or hard cancer, is most commonly met with in the breast and lymphatic glands. It occurs in two forms, either as a circumscribed mass, or infiltrated in the tissue of an organ. In either case it forms a hard, craggy. incompressible, and nodulated tumor, at first movable and unconnected with the skin, but soon acquiring deep-seated attachments, and implicating the integument. It grows slowly, seldom attaining a larger size than an orange. It is painful, aching generally, at times with much radiating and shooting pain through it; these sensations vary according to the part affected, and to the sensibility of the individual; the pains are especially severe after the tumor has been handled, and at night are of a lancinating, neuralgic character. It may thus continue in a chronic state for a considerable length of time, slowly increasing, gradually extending its deeper prolongations and implicating the more superficial parts. In some cases, more particularly in elderly people, scirrhus gives rise to atrophy of the organ in which it is seated, causing SCIRRHUS. 403 wrinkling and puckering of the surrounding skin, which becomes adherent to the tumor, which may thus continue in a very chronic state. The ulceration usually takes place by the skin becoming adherent at one point to the tumor either by dimpling in, being as it were drawn down towards it, or else by being pushed forwards, stretched and implicated in one of its more prominent masses; it then becomes of a dusky and livid red, somewhat glazed, and covered by a fine vascular net-work. Softening occurs at one point, where a crack or fissure forms; a clear, gummy drop of fluid exudes from this, and dries in a small scab upon the surface; this is followed by a somewhat bloody discharge of a thick and glutinous character; and the small patch of skin from which it issues becoming undermined, speedily sloughs away, leaving a circular ulcer. This gradually enlarges, becoming ragged and sloughy, with craggy everted edges, having irregular masses arising from its surface, and discharging a fetid sanious pus. The pain increases greatly, and the lymphatic glands be- coming involved the cachexy is fully developed, and the patient is destroyed by it, or by the secondary visceral deposits. In old people, ulceration of scirrhous masses often assumes an extremely chronic character, the growth in them not being endued with the same vitality as in the young. The ulcer in these cases is flat, sloughy, of a greyish-green color, hard and rugged, with puckered edges, much wrinkling of the surrounding skin, and exhaling the usual fetid odor. In younger persons, and especially in stout women with florid complexions, this disease usually makes rapid progress. So also, if inflammation be accidentally set up in the neighboring tissues, cancerous infiltration takes place in them, in consequence probably of the products of inflammation effused around the tumor undergoing cancerous transformation almost as soon as deposited. I had lately under my care an old man with a cancerous tumor of the leg, which, after re- maining stationary for seven years, became accidentally inflamed, and has since then increased with very great rapidity. Occasionally, but very rarely, scirrhous masses slough out, leaving a large ragged cavity, which may even cicatrize, and thus a spontaneous cure has been known to have occurred. The cancerous infiltration will extend to a considerable distance around the tumor into integu- ment that to the naked eye appears quite healthy, but which with the micro- scope will afford unequivocal evidence of the existence of cancer germs diffused through it. The cancer infiltration extends like a halo around the original tumor, and very probably shades off into the surrounding textures. It is of great importance in determining the question of operation to bear this in mind, and not to act on the supposition of the tumor being distinctly and abruptly defined. The secondary deposits from scirrhous tumors may take place in the viscera, or the lymphatic glands; in the former situation, they are usually of an en- cephaloid character, in the latter they assume the scirrhous form. After a scirrhous tumor has been removed, though still feeling firm under the fingers, it is not so hard as when it was in the body, owing, as Dr. Walshe observes, to the escape of its fluids and consequent loss of turgescence. On cutting it with a scalpel it usually creaks somewhat as it is divided, and pre- sents a whitish or bluish-white glistening surface, intersected by white bands, which apparently consist partly of new structure, partly of included cellular tissue. This section has not inaptly been compared to the appearance presented by a cut through a turnip or an unripe pear, hence termed napiform and api- noid by Walshe; and from its reticulated character, carcinoma reticulare, by Muller. On examining the fibrous stroma, or net-work, which forms the basis of the tumor, it will be found to be composed of fibrous or fibro-cellular tissue. The soft greyish-blue granular material seated in the meshes of this, may be squeezed or scraped off in a liquid state as cancer-juice. This is composed of a multitude of nucleated corpuscles, granules, granular cells, and globular, cau- date, or spindle-shaped bodies. 404 CANCER. The encephaloid or soft cancer, or, as it is often termed, medullary sarcoma, is the most malignant and rapidly-growing form of this disease. It is met with in the globe of the eye, in the nares or other cavities of the face, in the arti- cular ends of bones, the testes, and the breast, and often attains an enormous size, equal to that of an adult head, or of half the body. It occurs in two stages, either as a tumor, encysted or infiltrated, or as a fungus after protrusion through the skin. It commences as a tumor, which, though occasionally somewhat hard, is usu- ally from the first, or at all events soon becomes, soft and elastic, being more or less lobulated, growing rapidly, and having a semi-fluctuating feel. The skin covering it is at first pale and loose, with a large net-work of blue dilated veins spreading over it. As the tumor enlarges, the skin becomes adherent, disco- lored, of a purple-brown tint, and at last ulcerates at one point; from this a large fungous mass, rugged, irregular, dark-colored, and bleeding profusely, rapidly sprouts forth, constituting the affection to which Mr. Hey gave the appropriate term of fungus hsematodes; when once this condition has been reached death rapidly ensues from exhaustion and hemorrhage. Pulsation has been met with in particular forms of very vascular encephaloid; in these cases also a loud bruit has been detected that may be heard on the application of a stethoscope, synchronous with the pulsation and the heart's action. These symptoms have been most frequently met with in encephaloid tumors connected with bones, and may, unless care be taken, cause the disease to be confounded with aneurism. The constitutional cachexy in encephaloid occurs early, and is well marked, and secondary affections of the lymphatic glands and viscera often take place, occasionally of a scirrhous character. After removal the tumor is found to be very vascular, displaying on injection a close net-work of vessels. On a section being made, it commonly presents a soft pulpy white mass, closely resembling cerebral substance, stained and blotched with bloody patches, varying in color from a bright red to a maroon- brown, and dependent on blood that has been infiltrated into its substance. In other cases again, its section has been compared to that of a raw potato or a piece of boiled udder. On closer examination its tissue will be found to con- sist of a stroma of delicate fibres supporting the soft medullary or brain-like structure; this may be seen to be composed in a great measure of large quan- tities of corpuscles, nucleated, compound, and granular, fusiform, angular, clubbed, or caudate, often with two terminations. The colloid, gelatinous, or alveolar cancer, may occur in distinct masses, often of very large size, or be infiltrated in the tissue of organs; as it is most com- monly met with in the viscera, it does not so often fall under the observation of the surgeon as the other varieties of cancer. Yet it may form superficially, as is shown by a preparation in the University College Museum of a scirrhous breast containing colloid. In structure it consists of cells filled with a clear semi-transparent yellowish gelatinous or honey-like material, resembling indeed exactly the structure of a honey-comb. The septa forming these cells are distinctly fibrous, and regular in their arrangement. The gelatinous matter contains caudate and nucleated cells in considerable quantity, presenting the same characters as those of the other varieties of cancer. Melanosis or black cancer, has been specially studied by Sir Robert Carswell, who arranged it under the heads of punctiform melanosis, in which the dark pigmentary matter occurs in the shape of minute points or dots scattered over a considerable extent of surface. The tuberiform melanosis, occurring in tumors which vary in bulk from a millet-seed to an egg or an orange, always assuming a globular, ovoid, or lobulated shape, and being principally met with in the cellulo-adipose tissue, or on the surface of serous membranes. The stratiform ENCEPHALOID. 405 and liquiform melanosis, which take place principally upon serous membranes, or in accidental cavities where the black pigmentary matter looks not unlike Indian ink. Melanosis most frequently presents itself to the surgeon in con- nection with the eye, occasionally in the skin and subcutaneous cellular tissues, and rarely in the bones. It resembles somewhat in its general progress and characters the encephaloid form of cancer, ulcerating and throwing out dark fungous masses; occasionally indeed, as Carswell has pointed out, it is distinctly associated with the other varieties of this disease. In microscopic structure it somewhat resembles encephaloid, consisting of a stroma, with caudate, granular, and compound cells, but containing a large quantity of pigmentary matter in granules, molecules, and masses. The diagnosis of the different forms of cancer is not always easily made. Scirrhus when in tumor may very readily be confounded with fibrous tumors and various chronic glandular masses, or with the indurated atrophy of a part; in many of which cases indeed the diagnosis cannot be correctly effected until after removal. In other cases, however, the rugged feel, the lancinating pains, the tendency to the implication of the lymphatics, or to affection of the general health, will commonly serve to establish the diagnosis. When ulcerated, the previous condition of the tumor, the general character of the sore, and the microscopic examination of the debris, may serve to establish its true character. Encephaloid in tumor, may be confounded with abscess, cysts, fatty, erectile, and sanguineous tumors; and when pulsating, with aneurism. In these cases careful palpation, the existence of elasticity, without fluctuation, and the presence of the large and tortuous veins ramifying over the surface of the mass, may establish its true character. When it is fungating, it might be confounded with the sprouting intra-cystic growths, that sometimes spring from the interior of a cystic tumor. Here however a microscopic examination of the debris, as well as the existence or not of contamination of neighboring lymphatics, will estab- lish the true nature of the affection. The causes of cancer are often exceedingly obscure. In many cases it un- doubtedly is of an hereditary character, Velpeau says, in more than one-third of the patients he has met with, not that the disease itself is existent at birth, but that the tendency to it is connate; that tendency manifesting itself at those periods of life and in those organs in which cancer usually develops itself. It may, however, actually be a congenital affection; thus it has been met with in the eye at birth, and in the Museum of University College, is a preparation of a small melanotic tumor existing in the cerebellum of a child that only lived three days after birth. It may occur at all periods of life from the earliest ages; and will evince itself in persons from eighty to ninety years of age. According to Dr. Walshe, the mortality from cancer goes on steadily increasing till the eightieth year; hence the popular belief that the middle period of life is most obnoxious to it, would appear to be an erroneous one. All forms of cancer are not however met with in equal frequency at all ages; the encephaloid being the most common in the young, and scirrhus in the middle-aged and elderly. Colloid rarely occurs before the age of thirty. Cancer often appears without any exciting cause, when it is evidently, as in hereditary and connate cases, the result of some peculiar constitutional condition, the nature of which is altogether unknown to us, but under the influence of which the peculiar growth characterizing it springs up. In many cases, however, it can be dis- tinctly traced to some exciting cause, being immediately occasioned by a blow, injury, or other violence, or by a long-continued irritation of the part, that eventually becomes affected; thus in women a blow on the breast often gives rise to cancer, and the irritation of a broken tooth may occasion it in the tongue. It is a question whether external causes of this kind can give rise to the pro- duction of cancer without the previous existence of constitutional predisposition to the disease. That cancer even when apparently excited by local causes, may 406 CANCER. in reality be of constitutional origin, cannot admit of a doubt; more especially in those cases in which it is hereditary, or in which it makes its appearance almost simultaneously in different parts of the body with a strongly marked cachexy. But in many other instances it certainly appears to be strictly local in its origin, as when it slowly occurs after the infliction of some violence, and without any evidence of constitutional disturbance or contamination. Velpeau truly observes, that those organs which are most exposed to external irritation and violence, are most liable to cancer. It is impossible to look upon those cancers as ab initio constitutional, which arise from external causes in an other- wise healthy individual, slowly increasing in size without any tendency to mul- tiplication or sign of constitutional cachexy, until by the implication of the neighboring lymphatics or glands the cancer germs have entered the system. It is true that it may be argued that the cancer could not be excited locally in these cases, unless a tendency to it already existed in the system. But this appears to me to be a begging of the whole question; there is no proof of the existence of any constitutional infection at the time of the occurrence of the disease, or until it has existed for a sufficient length of time for the lymphatics to be affected and the blood to be poisoned; and it certainly appears to be more reasonable to look upon the local disease as the primary affection, occurring originally in a healthy constitution, but after a time infecting the system gene- rally, than to regard the mere local manifestation as in itself a proof of the con- stitutional nature of the disease. It is true that we are ignorant of the manner how a cancer-germ can be produced by the local action of the part in which it is generated, but we are as little acquainted with the essential mode of produc- tion of an exudation-cell or of a pus-corpuscle, which we know to be the result of strictly local actions; and it seems to me that the difficulty is in no way solved, but simply pushed back a step by the attempt to prove that in all cases of cancer-formation, a constitutional cause or predisposition exists, which im- presses the cancerous character upon local actions taking place in such a system. The cases in which cancer appears to be primarily and strictly a local affection, influencing the constitution secondarily, are by no means of unfrequent occur- rence—we commonly see for instance, a woman in perfect health receive a blow upon the breast, which gives rise to some passing inconvenience at the time; after a lapse of some weeks, though still with an unimpaired state of health, she notices a small lump of a scirrhous character. This may continue station- ary, or but slowly increase for months or years, and it is not until the lymphatics become enlarged, and the glands in the axilla indurated, that the constitution begins to suffer, and a tendency to secondary deposits to manifest itself. In such cases as these it is in vain to argue that the cancer could not have sprung up unless there were a constitutional tendency to it. There is in these cases no evidence whatever of any affection of the constitution, or of any general predisposition to cancerous disease, until after sufficient time has elapsed for the germs to be absorbed, and the blood to be poisoned by them (p. 410). TREATMENT OP CANCER. The treatment of cancer may be considered to be of a constitutional and of a local character. All curative constitutional treatment is, I believe, utterly useless in cases of cancer, no constitutional remedies appearing to have any influence on the progress of this disease. I am not acquainted with any case of cancer, either from my own observation, from conversation with other sur- geons, or from published statements, that affords satisfactory evidence of any internal remedy having cured this disease. It is true that many so-called cases of cancer have, at various times, been stated to have been cured by different medicines, but it must be borne in mind, that in a less advanced state of patho- logical knowledge than exists at the present day, almost all hard chronic TREATMENT OP CANCER. 407 tumors were called scirrhous, and many intractable ulcers, cancers; mistakes which are not unfrequently committed, and sometimes unavoidably so, even with the improved means of diagnosis that we at present possess. Not one of the many remedies that have been vaunted as being specific in this disease, and by which cures have been stated to have been effected, has obtained the con- fidence of the profession, or has, on further trial, corresponded in its effects to the statements of those who introduced it. I therefore think it but waste of time to discuss the supposed advantage to be derived from hemlock, sangui- naria, iron, arsenic, and iodine, in the treatment of cancer. But though cura- tive treatment can effect nothing in these cases, much may be effected in cases that do not admit of operation towards the alleviation of the patient's suffer- ings, and perhaps even towards retarding the progress of the disease, by proper palliative treatment. With this view, the diet should be mild, nutritious, easy of digestion, unstimulating, and sufficient to support the strength under the wearing influence of pain and discharge; and the preparations of opium, of conium, and hyosciamus, must be freely administered in order to relieve the patient's sufferings, and to procure rest. The local means are those upon which the surgeon places the greatest reliance in these affections. In order to prevent the rapid extension of the tumor, it is of great importance to subdue all local excitement going on within and around it; in proportion to the amount of action existing in the part the disease will usually extend with rapidity; any inflammatory condition of the neighboring tissues being especially prejudicial in this respect. Hence, under these circum- stances, the occasional application of a few leeches will often be of considerable service. No counter-irritation, however, ought to be employed in the vicinity of the cancerous part, as it only excites action in and around it, and hastens the process of ulceration; the skin especially is apt to become rapidly infiltrated by the cancerous disease under it, if irritated by the application of iodine and other stimulants. If the tumor be painful, and the skin covering it still un- broken, great relief may be obtained by the application of belladonna plasters. In some cases I have found powdered conium spread on cotton wadding, useful in the same way. As it is of importance to prevent, as long as possible, any breach of surface, the application of these sedative plasters and powders should be persevered in with the view of supporting the integument. The local appli- cation of ice, so as to freeze the tumor more or less completely, has been recom- mended of late years by Dr. J. Arnott; it may, possibly, in some cases retard the growth or lessen the pain, but there is no evidence to show that it can be considered as a curative agent. When the tumor is ulcerated, the foetor must be diminished by the applica- tion of weak solutions of the chlorides, to which opiates may be advantageously added with a view of lessening the pain. Caustics.—The employment of caustics for the destruction of cancers is of old date, and their use has, in all ages and countries, been resorted to by em- pirics, who profess to remove, by secret remedies less painful and more effica- cious than the knife, tumors of a malignant nature. As their application, to use Velpeau's expression, requires neither a knowledge of anatomy or of ope- rative surgery, they have always been popular with many who would hesitate to use the knife. In this country, however, they have never enjoyed any very extended reputation, and in fact have, perhaps, not been legitimately employed to the extent that they deserve, especially in ulcerated and recurrent cancers, or in those so situated on the skin and muco-cutaneous surfaces as not to admit of being very readily or safely extirpated by operation. The great objection to the use of caustics has been the severity and the con- tinuance of the pain induced by them, lasting not only for hours, but for days — more intense and prolonged than any occasioned by the knife; and as it is usually necessary, in order to destroy effectually the morbid growth, to repeat 408 CANCER. the application of the caustic several times, the suffering is often greater than the most resolute patient can submit to. The chief argument in favor of caustics is that when cancers are thus destroyed they are less liable to relapse than when extirpated by the knife. There is, however, no positive evidence in proof of this before the profession; but it is not improbable that the chemical action of the caustics may extend so widely into neighboring tissues as to destroy or render unproductive the cancer cells by which they are infiltrated, and on the development of which the local recurrence of the disease depends. Another advantage urged in favor of caustics, in the correctness of which Velpeau acquiesces, is, that enlarged lym- phatic glands are more likely to go down under their use than when the primary cancer is extirpated by the knife. Some of the advocates of the use of caus- tics in the treatment of cancer pretend that the agent employed exercises a specific action on the morbid structure, which is confined to it, and does not extend to the neighboring healthy tissues. But this assertion is entirely des- titute of foundation. The caustics that have been and that are employed in the treatment of cancers are very various. They cannot be used indiscriminately, and consequently we must briefly consider them separately. 1. The concentrated mineral acids, especially the anhydrous nitric and sul- phuric, are often advantageously employed. The concentrated nitric acid may be usefully applied to small superficial cancerous ulcers; it rapidly destroys the tissues, and does not spread too widely, but it is not potent enough for the destruction of tumors. The glacial sulphuric acid, rubbed into a black paste with powdered saffron, is the caustic which Velpeau extols as the most efficient in cancerous tumors, more particularly if of a fungating or bleeding kind. It converts the part to which it is applied into a thick, hard, carbonized eschar, with but little surrounding inflammation, and as its action is rapid, the pain is not prolonged. On the separation of the hard slough, a healthily granulating cavity will be left, which cicatrizes rapidly with much contraction. It also acts as a hemostatic, rapidly shrivelling and drying up large bleeding and discharging fungi. 2. The caustic alkalies, especially potass and lime, either alone or in combi- nation, in the shape of the Vienna paste, or fused into sticks, are very energetic in their action, but they have the disadvantage of spreading widely if applied to a large surface, and by softening or dissolving the parts, giving rise to a ten- dency to hemorrhage. They may, however, be advantageously used to small cancers of the face. 3. Various mineral salts, more particularly the chlorides of antimony, zinc, and bromium, the acid nitrate of mercury, and the arsenious acid, are often employed with much success in the treatment of cancers, ulcers, and growths. Of the various chlorides, that of zinc is the most useful. This is applied by being made into a paste with from one to four parts of flour, moistened with a little water. It must, in order to act, be applied to a raw surface. M. Can- quoin states that a paste, made of equal parts of the chloride and of flour, four lines in thickness, and applied for forty-eight hours, destroys the parts to the depth of one-and-a-half inch. Where of less strength and substance, its action is proportionately limited. It may sometimes be used in the form of small sticks, which are pushed deeply in several directions into the substance of the part to be destroyed. In other cases the tumor may be deeply and rapidly attacked by applying a layer of the chloride of zinc paste over the whole of its surface. The slough produced by this application is then incised in several directions, until the parts beneath, to which the caustic has not penetrated, are reached by the incisions so made; pieces of lint covered with the paste are put into them, and afterwards fresh incisions made, until the cauterizing influence is extended to the bottom of the tumor, which finally sloughs out in a mass. Of the utility of TREATMENT OP CANCER. 409 his caustic there can be no doubt, but the chief objection to its use is the inten- ity and continuance of the pain occasioned by it. Mr. L. Parker has suggested that this may be prevented or lessened by freezing the part. Landolfi has recom- mended the use of the chloride of bromium in combination with those of gold and zinc, but this caustic does not appear to possess any decided advantage over the simple chloride of zinc, and is objectionable on account of the fumes evolved during its use. Arsenic exercises a powerful action upon cancerous growths, and constitutes the chief ingredient in many of the secret preparations used by empirics; it is, however, a dangerous agent, and excites great inflammation and pain. If too freely used, it may induce poisoning, and not a few deaths have resulted in this way; it should, accordingly, not be applied to a surface exceeding a shilling in size at one time. The most convenient mode of applying it appears to be Manec's paste, composed of one part of arsenious acid to eight of cinnebar, and four of burnt sponge, rubbed down to a proper consistence with a little water. The sulphate of zinc, dried, finely levigated, and made into a paste with gly- cerine, or an ointment with axunge, has been very strongly recommended by Dr. Simpson, as one of the most efficient and convenient of all caustics in rodent and cancerous ulcers. In action it somewhat resembles the chloride of zinc, but is less painful. The treatment by compression is a plan that has been alternately greatly ex- tolled and much depreciated. It was fully tried at the Middlesex Hospital, by Mr. Young, forty years ago, and unfavorably reported upon by Sir Charles Bell at that time; it consequently fell into disuse in this country, but was revived by Recamier in France, and employed largely by him. Although he published a favorable account of this practice, it made but little progress amongst French surgeons, the only one who seems to have used it to any extent being M. Tan- chou, who employs a peculiar topical medication conjoined with it. In this country the practice fell into complete oblivion, until Dr. Arnott, some years ago, invented a mode of employing pressure by means of an elastic air-cushion; since which time it has been pretty extensively employed with varying degrees of success. In employing pressure, Young principally had recourse to plasters and ban- dages. Becamier used amadou applied with an elastic roller; and Tanchou recommends spring pads, under which small bags or pieces of cotton wadding impregnated with various medicinal substances are placed, so as to protect the skin and act upon the tumor. Dr. Arnott's plan consists of pressure exercised by a Mackintosh air bag, held in its place by straps, and pressed upon by a truss-spring, the pressure exercised by which may be made to vary from two- and-a-half to twelve or even sixteen pounds. These different plans should not be employed indiscriminately, but may all be of service in particular cases. I have employed all these methods, but have never found any permanent advan- tage from any of them. The first question that necessarily arises in reference to the employment of pressure in these cases, is whether it can effect a cure. This it could only be expected to do by producing atrophy and the subsequent absorption of the strictly local forms of cancer. The only case on record, with any pretension to a conclusive character in this respect, is one related by Dr. Walshe, in his excel- lent " Treatise on Cancer," of the cure of a tumor of the breast, believed to be cancerous, by compression. But even this instance I cannot look upon as by any means conclusive; for although no one can entertain a higher opinion than I do of the very remarkable diagnostic tact possessed by Dr. Walshe, yet I think there can be no doubt in the mind of any surgeon that it is absolutely impos- sible to determine in many cases, by any amount of diagnostic skill, the true nature of a chronic tumor of the breast, and that in fact we constantly see the most experienced practitioners find after the removal of the tumor that it was 410 CANCER. of a different character to what they had previously anticipated. This difficulty attaches to Dr. Walshe's case, and I think that we possess no proof that the tumor of the breast, which underwent absorption under the pressure of Dr. Ar- nott's apparatus, was of a truly cancerous character, and that it might not have been a chronic mammary tumor or some similar growth, that we know will disappear under this kind of treatment. But if compression cannot be shown ever to have cured a cancer,—can it not retard the progress or relieve the sufferings attendant upon this disease ? I believe that in some cases it may certainly do both, though in others it is as unquestionably injurious. It appears occasionally to retard the growth of the tumor, when applied in the early stage, simply by preventing its expansion, and perhaps by diminishing the supply of blood sent to it by compressing its nutrient vessels, and by causing absorption of surrounding inflammatory infiltration; in these cases likewise it relieves for a time the pain by lessening the turgescence of the part. In other cases, however, I have known it to act injuriously by pressing out and diffusing the tumor more widely, appearing to increase the ten- dency to implication of neighboring parts, and occasioning great suffering. When the tumor is ulcerated, or if the skin covering it is inflamed, pressure cannot be employed with any advantage; and most commonly irritable, sensitive patients cannot support the constriction of the chest that it induces. Excision.—With regard to the question of removing cancers by the knife, much difference of opinion exists amongst surgeons, for though all deprecate indiscriminate recourse to this means in this affection, some go so far as to dis- pute the propriety of ever operating for this disease, whilst others restrict the operation to certain cases of a favorable character. These questions are neces- sarily of considerable importance, and require attentive consideration. The great objection that has been urged against operating in these cases is, that cancer being assumed to be from the first a constitutional affection, it is useless to remove the local tumor, leaving the constitutional vice (p. 406). For such an argument as this to have any value, it must first be shown that cancer is ab origine a constitutional affection, and that it is not a local disease in the first instance, which being allowed to remain unchecked will at last contaminate and poison the system. The evidence we possess would, however, rather lead us to the opposite conclusion, namely, that cancer is originally local, and only becomes secondarily constitutional. This opinion, which Velpeau strongly sup- ports, is founded on the following reasons: — 1st. We constantly see cancerous tumors spring up in individuals who have always enjoyed perfect health, and who are to all appearances perfectly well at the time of the occurrence of the disease. 2d. These tumors are not unfrequently the result of some local injury or irritation. 3d. The constitutional health does not in the majority of cases appear to suffer until some weeks or months have elapsed, when as the lymphatics or glands become implicated, or neighboring tissues invaded, signs of cachexy set in. 4th. If the disease be removed in the early stage and before neighboring parts have become contaminated, the health often improves materially. 5th. In the great majority of cases the patient remains free from any recur- rence of the disease for some considerable period. 6th. In some instances no recurrence whatever takes place, the disease being eradicated from the system, which could not be the case if it were constitu- tional. 7th. We observe the same tendency to recurrence after removal, and to secondary deposit in distinct organs in other tumors which are incontestably primarily local, such as the fibro-plastic and the enchondromatous, and only be- come constitutional in their more advanced stages, and in a secondary manner. OPERATION FOR CANCER. 411 The objections that have been urged against the general propriety of opera- ting in cases of cancer, do not apply so much to the operation itself, the risk attending which is not greater than that of other operations of similar magni- tude, as to the liability of the patient speedily suffering from a return of the disease, so that an operation that is at least unnecessary will have been per- formed. That this objection is in a great measure a valid one, is undoubted; the experience of all surgeons tending to establish the fact that the majority of patients operated upon for cancer die eventually, and usually within a limited time, from a recurrence of the disease. Thus, Sir A. Cooper states, that in only nine or ten cases out of a hundred, did the disease not return in three years; and Brodie has found that it generally proves fatal in two or three years after the operation. After removal of the tumor, the disease may return in the cicatrix, even before this is healed : in the neighboring lymphatic glands with or without the cicatrix having been involved, or in internal organs. When it returns in the cicatrix, it usually makes its appearance in the form of small hard nodules of a purplish-red color, and covered with a very thin integument, which speedily runs into ulceration, presenting the ordinary characters of the cancerous sore. The disease is especially apt to recur if the skin have become involved, if the lymphatic glands are enlarged, or if there be constitutional cachexy before the operation; so also if the tumor is growing rapidly at the time of removal, and especially if the patient be robust and strong with a florid complexion. In determining the question of operating in cases of cancer, several points of great importance present themselves for the consideration of the surgeon. He has first to consider whether the operation is likely to free his patient com- pletely from the affection; or, in the event of its not doing so, whether at least life may not be prolonged by the removal of the cancerous tumor; and, lastly, even though the patient be eventually carried off as speedily as he otherwise would have been, whether his sufferings may not be much lessened by the removal of the local affection. That in some cases a cancerous tumor may be removed With every expectation of the patient being completely freed from the disease, cannot, I think, be doubted; although it may be true that such instances are not of frequent occurrence. Yet they not unfrequently fall under the observation of surgeons, and would certainly tend to prove that the affection is not in all cases of a con- stitutional character, and that if we can happily succeed in removing it during its local condition, there is a good prospect that the patient may be rescued from a return of the affection. Velpeau states that he has perfectly cured patients by the removal of cancerous tumors, at least that no return has taken place for 12, 15, or 20 years after extirpation. The evidence of Sir B. Brodie on this point is extremely valuable; writing in 1846, that eminent surgeon states, that " So long ago as 1832, I removed a breast affected with a scirrhous tumor, and the lady is still in good health—at least, she was so last year. Since the operation she has married, and had children. Last year I was called to see a lady on account of another complaint, on whom I performed the operation thirteen years ago, and found that she continued free from the old disease; and, very lately, I have heard of another lady, whose scirrhous breast I removed six years ago, and who continues well." The evidence of Mr. Fergusson is also very positive on this point, and he speaks in a manner with which I perfectly agree. ^ He says, "Nevertheless, as excision gives the only chance of security —a point on which most parties seem to agree—an operation should always be resorted to, provided the knife can be carried beyond the supposed limits of the disease; and, moreover, I deem it one of the duties of the practitioner to urge the patient to submit to such a proceeding." The opinions of these eminent surgeons, supported as it is by the general practice of the profession, tends to show that in some cases, at least, the disease may apparently be extirpated from 412 CANCER. the system by excising the tumor before the constitution has become implicated. But even though, in many cases, we may not expect to accomplish so desirable a result as this, and to cure the patient completely by operative procedure, may we not reasonably hope to improve his health, to prolong his life, or to relieve the sufferings to which he is subjected, by this means. I am decidedly of opinion that we may do so, and though a patient may at last be carried off by some of the recurrent forms of cancerous disease, his health may have been improved, his life may have been prolonged, and much suffering may have been spared him by a timely operation. This is more particularly the case in en- cephaloid cancer, in which early removal of the disease is unquestionably suc- cessful, in many cases, in prolonging life. The observations of Mr. Paget, on this point, are peculiarly valuable. He states the average duration of life of those patients laboring under this form of disease, in whom the primary affec- tion is removed, to be about 34 months; whilst the average life of those in whom the disease is allowed to run its course, is scarcely more than one year. But I think that the introduction of anaesthetic agents into operative surgery has very materially altered the bearings of this important question. So long as an operation was a source of great pain, and of much consequent anxiety and dread, a surgeon might very properly hesitate in subjecting his patient to severe suffering with so doubtful a result; but now that a patient can be freed by a painless procedure from a source of much and constant annoyance, discomfort, and suffering, the surgeon may feel himself justified in thus affording him a few months or years of comparative ease, though he may be fully aware that at the expiration of that time the affection may return, and will certainly prove fatal. Even then, his condition may be much improved, for the recurrent is often less distressing to the patient than the primary disease, for, as it often takes place in internal organs, it is not attended with the same amount of local pain and distress. In discussing the propriety of operating in a case of cancer, the surgeon can, however, have little to do with general or abstract considerations. He has to determine what had best be done in the particular case that he is actually con- sidering, and it will serve him little in coming to a conclusion as to the line of practice that he should adopt, to refer to the statistics of the gross results of operations, or to general comparisons between the results of cases that are not operated upon and those that are. The whole question narrows itself to the point as to what should best be done in order to prolong the life, or relieve the suffering, of the particular individual whose case is being considered. In order to come to some definite conclusion on this, it is necessary to classify the different cases of cancer, and to arrange them under the heads of those in which no operation is justifiable; those in which the result of any such procedure would be very doubtful; and, lastly, those in which an operation is attended with a fair prospect of success. Cases not admitting of operation. — 1st. The operation ought never to be performed in those cases in which there are several cancerous tumors, existing in different parts of the body at the same time. Here the disease is evidently constitutional, and could not be eradicated by any series of operations. 2d. Then, again, if the cancerous cachexy is strongly developed, or if the disease be hereditary, it is useless to remove a local affection, as the malignant action will certainly manifest itself elsewhere, or, perhaps, even speedily return in the cicatrix. 3d. So also if the tumor be of very rapid growth, and be still increasing, there would appear to be so vigorous a local tendency to cancerous deposit, that it will speedily develop itself again in the cicatrix. 4th. If the tumor be so situated that it cannot be completely and entirely extirpated by cutting widely into the surrounding parts, it ought not to be meddled with; otherwise the affection will to a certainty return in the cicatrix before it has closed. It is not alone necessary to remove the tumor, but the surrounding OPERATION FOR CANCER. 413 tissues to some extent, even if apparently healthy. 5th. If the whole of the affected organ, as a bone, cannot be removed, or, if the skin and glands be involved, it is useless to attempt the extirpation of the growth, as a speedy relapse may be confidently looked for. 6th. In the very chronic and indurated cancers of old people, it is often well not to interfere, as in these cases the affection makes such slow progress, that it does not appear in any way to shorten life, and the mere operation might be attended with serious risk at an advanced age. Doubtful cases. — Those cases in which the result of an operation is of an extremely doubtful character, but in which no other means offer the slightest prospect of relief to the patient, have next to be considered. 1st. Cancers of the eye, tongue, and of the testes belong to this category, for though more liable to return than similar affections of any other part of the body, yet they may be considered fit cases for operation, inasmuch as in no other way has the patient the slightest chance of being relieved from his disease. 2d. In those cancers that are already ulcerated, the surgeon may sometimes operate in order to give the patient ease from present suffering, or, perhaps, as in some cases recorded by Brodie, with the view of prolonging the duration of life; but he can have little expectation of effecting a permanent cure. 3d. If the tumor be of so large a size, or be so situated that its removal cannot be undertaken without so serious an operation as to occasion in itself considerable risk, the propriety of operating is always very doubtful. Cases for operation. — Those cases of cancer in which an operation is, in my opinion, not only perfectly justifiable, but should be urged upon the patient as affording the best prospect of preserving his life, are those in which the disease has appeared to originate from a strictly local cause in persons otherwise in good health, in whom there is no cachexy or hereditary taint. If the tumor be of a scirrhous character, slow in its progress, single, distinctly circumscribed, without adhesions to, or implication of, the skin or glands, and more especially if it be attended with much pain, or with immediate risk to life from any cause, and if the whole of the growth, together with a sufficient quantity of the neighboring healthy tissues in which it is imbedded can be removed with care, the case may be looked upon as a fit one for operation. In all encephaloid cancers also, early operation should be practised with the view of prolonging life. An important question in connection with operations for cancer, is at what period of the growth they may be done with the best prospect of success. Most surgeons, taking a common-sense view of this question, are in favor of removing the affection as early as possible, feeling that as it is difficult to say when the local form of the disease becomes constitutional, it is safer to remove it as soon as its true nature has been ascertained; and I confess that I can see no advantage that can be gained by delay. The necessity for early operation in medullary cancer is admitted by all, but with regard to scirrhous cancer, the opinion is entertained by some, that in many cases there is a better pros- pect of success if the operation be delayed: and it is stated by Hervez de Chagoin and Leroy d'Etiolles, that the result of those cases operated on after the cancer has lasted for some time, is more favorable than that of those in which an early operation has been done; the cancer often appearing to be arrested in its development and to localize itself as it becomes more chronic, and having consequently a less tendency to speedy return after removal. That the result of operations in such selected cases is favorable, is probable enough, as it may be reasonably supposed that the more active varieties of cancer, those that possess the greatest amount of vegetative activity and of reproductive power, may have got into a condition unfavorable to operation, or even may have carried off the patient before any period of arrest in their growth has occurred, during which their extirpation could be practised with a fair prospect 414 CANCER. of success. In delaying operation there is, however, much danger lest valuable time be lost in the employment of means which, ineffective in arresting the disease, may become positively injurious by allowing time to the morbid growth to contaminate the glandular system, or to extend widely through neighboring tissues. If we look upon a cancer as a morbid growth that must necessarily destroy life, either by changes taking place in its own substance or by the contamination of the system, and that is intractable to all medication, whether topical or constitutional, we must look upon its extirpation as the only resource that Surgery offers; and we may assuredly infer, that the liability to constitu- tional infection, and wide-spread local contamination, will be less in proportion to the early removal of the morbid mass. EPITHELIAL CANCER. — EPITHELIOMA, Epithelial cancer differs from the other varieties of the disease in its anatomical structure, in being seated on the cutaneous, or more frequently, the mucous or muco-cutaneous surfaces; and in its being but very seldom the cause of secondary visceral deposits. It resembles the other forms of cancer, however, in its tendency to local infiltration and ulceration, in its extension to the lymphatic system, and in the induction of death by cachexy. This affection is chiefly met with in the neighborhood of the outlets of the body, upon the muco-cutaneous surfaces, being commonly seated upon the lips, the tongue, the cheek, the scrotum, the anus, and the uterus; but it may occur upon the skin of the extremities and trunk, chiefly in the hands, feet, and back. It commences either as a small tubercle, which rapidly ulcerates, or appears from the first as an intractable ulcer of limited size, with hard and everted edges, and a foul surface; it slowly spreads, and appears at first to be local, but after a time contaminating the glands in the neighborhood, it induces cachexy, and destroys the patient by exhaustion. It seldom occurs secondarily in the viscera, though, the liver, lungs, and heart have been observed to be affected; but extensive deposits in the lymphatic glands in the vicinity of the parts affected, even deep in the iliac and pelvic regions, invariably take place after the disease has lasted for some time. It may form in the submucous cellular tissue as a distinct rounded pendulous or fibrous-looking tumor. I removed lately such a growth from the inside of the cheek of an old woman; it looked fibrous on section, but was an epithelial cancer, about the size of a cherry, round and pedunculated. On examination an epithelial cancer will be found to be com- posed of a fibrous basis, with a large quantity of condensed and morbid epithelial scales, closely packed upon it. These scales so closely resemble those of the Fig. 151. Cells from epithelial cancer Is and burst into the mo^ vnththT^^ °*the8G CaTS d°e! n0t differ from that of aneurisms connected with the carotid arteries, and seated at the upper part of the neck • but we J* not in possession of a sufficient number of £11£ enable us to TeLr^Zl th bTwf SS1°n What the r^Ult °f SUrSical interference in them is lik ly to be. If we could give an opinion from the limited number of cases at present P nLV of'the r3 "J t^ ^ ***»* n°fc t0 entertain a ^ « ^t^^lgrfto^Hsss: nt00' as-applied to, Ve cases- m*™\. c xu """'& ™ #lue situation ot the aneurism against the mucoim 546 subclavian aneurism. sion of the artery leading into it, which, in accordance with the principles that have been laid down in speaking of the Hunterian operation, is necessary. After the carotid artery has passed through the carotid canal, and has entered the cavity of the cranium, it or its branches may occasionally be the subject of aneurism; but *as the consideration of these intracranial aneurisms does not fall within the province of the surgeon, it need not detain us. ANEURISM OF THE SUBCLAVIAN ARTERY. Aneurisms of the subclavian occur in order of frequency between those of the carotid and of the brachio-cephalic. They are most frequently met with on the right side, in the proportion of nearly three to one, and this would appear to be in a great measure dependent on their being occasioned by direct violence, or of repeated and prolonged exertion of the arm; thus they commonly occur from falls, blows upon the shoulder, or excessive fatigue of this extremity. From the fact of the aneurisms arising from external violence, we should expect to meet with them most frequently in males, and this we do in a remarkable manner. Of 32 cases, I find only 2 occurring in females, and in both these instances the disease resulted from injury. The disease may be seated in any part of the vessel on the right side, though most commonly it is not dilated until after it has got beyond the scaleni. On the left side it never occurs before its emergence from the thorax, and then, as on the right, aneurism most com- monly happens in the third part of the course of the vessel. An aneurism of the subclavian artery is characterized by a pulsating com- pressible tumor of an elongated or ovoid shape, situated at the base of the posterior inferior triangle of the neck, immediately above the clavicle. If it be small, it will disappear behind this bone on the shoulder being raised; as it increases in size, it fills up the whole of the space between the clavicle and the trapezius, often attaining a very considerable bulk. In consequence of the pressure which it exercises on the brachial plexus of nerves, there is pain, often attended by numbness, and extending down the arm and fingers, usually with some weakness of these parts. In some instances there is a spasmodic affection of the diaphragm, owing to irritation of the phrenic nerve. The external jugular vein is commonly distended and varicose, with oedema of the hand and arm, or even of the side of the body. The tumor does not increase rapidly in size, owing to its being tightly compressed by the surrounding parts, and as the disease never extends inwards, it does not interfere with the trachea or oesoph- agus. In some cases it has been known to extend downwards and backwards, so as to implicate the pleura and the summit of the lung. The diagnosis of these aneurisms is usually easy, and presents no point of a special character. As they increase in size they may become diffused, and burst either externally or into the pleural sac. In some instances a spontaneous cure has been observed. The treatment of subclavian aneurism is in the highest degree unsatisfactory. The attempt at obtaining consolidation of the tumor by constitutional means, by galvano-puncture, or compression, have hitherto failed, except in some very rare instances. A case is reported by Mr. Yeatman of the cure of subclavian aneurism by Valsalva's plan in eighteen months; and another by Dr. Abeille, in which the tumor was consolidated by galvano-puncture. Manipulation, as recommended by Mr. Fergusson, has succeeded in the hands of Mr. Little, and undoubtedly deserves a trial in these cases, when we consider the extreme danger and almost universal want of success that attends other means of cure. The ligature of the brachio-cephalic, and of the subclavian itself, before, be- tween, and beyond the scaleni muscles, has been practised for the cure of this form of aneurism; it has likewise been proposed to apply the distal operation to the treatment of this disease, and to amputate at the shoulder-joint. SUBCLAVIAN ANEURISM. 547 When an aneurism is situated on the right subclavian artery on the tracheal side of the scaleni, there is no way in which the flow of blood through it can be arrested, except by the ligature of the brachio-cephalic artery. When it is situated beyond the scaleni, or even between these muscles, the ligature of the vessel has been practised in the first part of its course before it reaches these muscles. For subclavian aneurisms on the left side, in these situations, no operation conducted on the Hunterian principle would be practicable. CASES OF LIGATURE OF BRACHIO-CEPHALIC. AGE NATURE OF OPERATOR. AND SEX. DISEASE. RESULT. REMARKS. 1. MOTT. m. Subclavian Died on 26th Tied an inch below bifurcation. 67. aneurism. day. Ligature separated in four-teen days. Hemorrhage in twenty-five, stopped by pres-sure. Recurred in twenty-six. 2. Graefe. Subclavian Died on 67th Ligature separated in fourteen aneurism. day. days. Died of hemorrhage. 3. Hall. Subclavian Died on 5th Coats of artery were diseased aneurism. day. and gave way. Wound plugged without success. 4. Dupuytren. Died. Case referred to as occurring 5. Norman. Died. in the practice of Dupuytren. 6. Bland. m. Subclavian Died on 18th Hemorrhage came on on the 31. aneurism. day. seventeenth and eighteenth days. Ligature applied to upper portion of artery. 7. LlZARS. Subclavian Died on 21st Ligature separated on seven- aneurism. day. teenth day. Hemorrhage on nineteenth. 8. Hutin. m. Hemorrhage Died in 12 Punctured wound in axilla, for 26. from axilla after liga-ture of sub-clavian. hours. which subclavian was tied; secondary hemorrhage, and then b. c. ligatured. 9. Arendt. Subclavian Died on 8th Inflammation of lung, pleura, aneurism. day. and aneurismal sac. ^'v'rThe artery was cut down uP°n> but not hgatured, by Porter, Post, Aston Key and Hoffman. ■" Ligature of the brachio-cephalic—Let us now proceed to examine the results that have attended these operative procedures. The brachio-cephalic artery, as may be seen by the accompanying table, has been ligatured 9 times and in every instance with a fatal result. In 4 other instances, the operation has been commenced, but abandoned owing to unforseen difficulties, and this by three of the most skilful operators that their respective countries can boast of Although in reasoning on the propriety of performing an operation, it is not in general worth while taking the difficulties that a surgeon may encounter into consideration provided the operation be at last practicable; yet, when we consider the fact of the ligature of the brachio-cephalic having been attempted and in consequence of unforeseen and insurmountable difficulties left unconcluded in so large a proportion as one-fourth of the cases, and these in the hands of surgeons who were as well able as any to accomplish whatever was in the power of operative surgery to do, we may well hesitate upon the difficulties that beset the operation itself, before proceeding to the consideration of its results. The difficulties to which I allude, do not consist merely in the position and anatomical relations of the vessel, but rather in the condition in which the artery and 548 ANEURISM OF THE SUBCLAVIAN. adjacent structures may be found after the vessel is exposed. Thus, in Mr. Porter's case, the aneurism, which was a large one, occupied the whole of the posterior inferior triangle of the neck, being nearly six inches broad; as no pulsation was traceable in the vessels beyond the aneurism, it was useless to attempt the ligature on the distal side. On exposing the brachio-cephalic, that vessel was found to be diseased, and it was not thought desirable to pass the ligature round it. In consequence of the exposure of the artery, however, the pulsation in the tumor gradually diminished, and at last ceased entirely, its bulk also becoming less. In Mr. Key's case, in which it was impracticable to pass the ligature, it was found after death that the brachio-cephalic was diseased, being dilated imme- diately after its origin into an oblong tumor, which occupied the whole of the artery. It is remarkable that in this case, as in Mr. Porter's, inflammation seems to have taken place in the artery in consequence of the necessary hand- ling to which it was subjected, and that the pulsation in the sac consequently diminished. It would thus appear, that even after the difficulties of the operation have been surmounted, (and these, from the depth of the vessel, its proximity to the centre of the circulation, the neighborhood of large veins, which may become turgid, and a wound of which not only obscures the line of incision with venous blood, but induces a risk of the entrance of air into the circulation, are of serious magnitude,) and the artery has been exposed, its coats may be found so diseased, or its calibre so increased, that it may be undesirable or impossible to pass a ligature round it. The failure in deligating the artery would, however, as we shall immediately see, appear to be less disastrous in its consequences than success in that attempt; for of the 3 cases that have just been referred to, in which this attempt was made and did not succeed, 1 was cured of the disease, the artery being obliterated by adhesive inflammation; and in another, Mr. Key's patient, an attempt to set up this action appears to have been made, the tumor becoming solid and ceasing to pulsate, whereas in every case in which the vessel was ligatured, a fatal result speedily ensued. The results of the ligature of the vessel are in the highest degree discouraging; for of the 9 cases in which it has been done, not one recovered. Death occurred from secondary hemorrhage in 4 cases, from inflammation of lungs or pleura in 2, and in 3 from causes that are not mentioned. In one case, that of Hall, the artery was transfixed by the aneurism needle; hemorrhage occurred at the time, which was arrested by plugging, and did not recur, the patient dying from other causes. In 3 cases, those of Mott, Bland, and Lizars, the hemorrhage came on shortly after the separation of the ligature; but in Graefe's (the most successful) it did not occur for fifty-one days after this, the cicatrix in the artery having then probably given way under the influence of some imprudent movement on the part of the patient. With such results as these, there can, I think, be but one opinion as to the propriety of such an operation being again had recourse to. As its performance has hitherto in every instance entailed death, and, in all cases but one, a speedy death to the patient, it should without doubt be banished from surgical practice; and I can think of no circumstances that should induce a surgeon, in the face of the consequences that have hitherto invariably followed the application of a ligature to this artery, again having recourse to such a procedure. Ligature of the subclavian.—If the aneurism be situated on the right subclavian artery, between or beyond the scaleni, that vessel has* been ligatured on the tracheal side of these muscles; on the left side this operation is not prac- ticable, on account of the depth at which the artery is situated. When we con- sider the anatomical relations of that portion of the right subclavian, which intervenes between the brachio-cephalic artery and the tracheal edge of the scalenus anticus muscle, we are at once struck with the great difficulties of this LIGATURE OF THE SUBCLAVIAN. 549 undertaking; and when we reflect on the position in which the ligature will be placed between the onward current of blood in the brachio-cephalic on the one side, and the regurgitant stream conveyed by the vertebral, the thyroid axis, the internal mammary and intercostal, into the subclavian, immediately beyond the seat of deligation on the other side, we could scarcely, in accordance with those principles on which the formation of a coagulum within a ligatured vessel takes place, anticipate any but the most disastrous results. In reference to the mere difficulties of the operation, Mr. Fergusson justly characterizes it as the most serious in surgery; the proximity of the common carotid artery on one side, the internal jugular vein on the other, the vena inno- minata below, the par vagum and numerous small venous trunks in front, the recurrent laryngeal nerve and pleura behind, constitute relations of sufficient importance to justify Mr. Fergusson's opinion. But supposing these difficulties overcome, and the ligature applied, this must be situated, as has just been stated, in such a position, with a strong current of blood flowing upon either side of it, as to render the formation of an internal coagulum, and consequently occlusion of the artery, impossible, and thus to lead inevitably to the occurrence of a fatal hemorrhage on the separation of the ligature. Besides the danger of secondary hemorrhage from these causes, there would be the additional risk of the coats of the artery being diseased, as we commonly find them in a more or less morbid state in the immediate vicinity of aneurisms; and thus being rendered insus- ceptible of healthy inflammation, ulceration and sloughing would take place along the track of the ligature, thus causing the probability of a recurrence of hemorrhage. Thus, in Colles's case, it was found on exposing the subclavian artery, that the aneurism had extended in such a way towards the carotid, that it was doubtful whether any part of the affected vessel continued sound. On exposing it fully, it was found that only a space of the vessel three lines in length remained free between the sac and the bifurcation of the brachio-cephalic, and it was in this narrow space that the ligature was applied. The subclavian has been ligatured on the tracheal side of the scaleni muscles in 7 cases, all of which have proved fatal, 6 from hemorrhage, and 1 from inflam- mation of the pericardium and pleura. The cases are as follow:— SURGEON. sex. AGE. date of death. cause of death. COLLES. MOTT. Hayden. O'Reilly. Partridge. Liston.1 Liston.2 m. f. f. m. m. m. m. 33. 21. 57. 39. 38. 4th day. 18th day. 12th day. 13th day. 4th day. 13th day. 36th day. Hemorrhage. Hemorrhage. Hemorrhage. Hemorrhage. ■ Pericarditis and pleurisy. Hemorrhage. Hemorrhage. Thus it will be seen, that if this operation is bad in principle it is most unfor- tunate in practice. This table is, to my mind, conclusive as to the merits of the operation, the patient having in every case but one been carried off by secondary hemorrhage from the distal side of the ligature, in consequence of the close proximity of numerous collateral branches (fig. 190), and in this exceptional case the operation, although performed with the utmost delicacy and skill, proving fatal from pericarditis and pleurisy before the period at which secondary hemorrhage might have been expected. Mr. Liston, in one case, ligatured the root of the common carotid, as well as that of the subclavian, 1 In this case the carotid was also tied, but the hemorrhage came from the subclavian (fig- 191)- 3 Fig. 190. 550 ANEURISM OF THE SUBCLAVIAN. hoping in this way to diminish the risk of the supervention of this fatal hemorrhage, by arresting the current of blood which, by sweeping into tho carotid past the mouth of the Fig. 190. subclavian, necessarily washed away any coagulum that would otherwise have formed in this artery. But his ex- pectations were not realized, hemorrhage taking place as usual, and from that portion of the artery which lay on the distal side of the ligature (fig. 191), the blood having been carried into this part of the vessel in a retrograde course, through the connection exist- ing between its vessels arising from it at this point, and those on the opposite side of the head and neck, as illustrated by the annexed cut, taken from the preparation of the case in the University College Museum. Indeed this is the great danger to Fig. 191. be apprehended after ligature of the subclavian artery on the tra- cheal side of the scaleni, depending as it does on the anatomical rela- tions and connections of the vessel, which no skill on the part of the operator can in any way lessen, and which, in my opinion, ought cer- tainly to cause this operation to be banished from surgical practice. When an aneurism is situated on the" subclavian artery, in the posterior inferior triangle of the neck, it is necessarily impossible to ligature that vessel beyond the scaleni, as there would not be suffi- cient room for the exposure of the artery, which, even if laid bare would in all probability be found in too diseased a condition to bear the appli- cation of a ligature. ^ Thus it will be seen, that in every case in which an aneurism of the subcla- vian artery has been subjected to operation, whether by ligature of the brachio- cephalic or of the subclavian itself internul to the scaleni, the result has been a fatal one. As this unfortunate termination to every case that has yet been sub- mitted to surgical interference is in no way to be attributed to want of skill on the part of the operators, who arc, without exception, men greatly distinguished for the possession of this very quality, but is solely dependent on certain anato- mical peculiarities in the arrangement of these vessels, by which their success- ful ligature has been rendered impossible, a repetition of these attempts, which may hasten the patient's death, can scarcely be considered justifiable. What then are we to do ? Are we to leave patients laboring under aneurism of the subclavian artery to inevitable death, without making an effort to save them ? or does surgery offer other modes of treatment besides those just mentioned, by which we may hope to arrive at more successful results ? Without mentioning manipulation, or galvano-puncture, which is certainly LIGATURE OF THE SUBCLAVIAN. 551 deserving of further trials in combination with appropriate constitutional treat- ment, three modes of treatment present themselves : — 1st. Compression on the artery where it passes over the first rib, and conse- quently on the distal side of the tumor. 2d. Ligature of it on the distal side, above or below the clavicle. 3d. Amputation at the shoulder-joint, and the distal ligature of artery. 1st. Compression of the artery on the distal side of the sac could only be effected where it crosses the first rib, and consequently would only be applicable to aneurisms of the first part of this vessel. This plan has never been tried, partly, perhaps, on account of the difficulty in applying pressure in this situa- tion, and partly, probably, on account of the want of success that has attended procedures of this kind when applied to vessels in other situations. The difficulty in applying the compression might, I think, be overcome by the use of the instrument of which a representation is given by Bourgery; and the efficiency of the compression would be materially increased by the employ- ment of the galvano-puncture at the same time, and in this way a coagulum might be formed in the sac. Although much ought not to be expected from this mode of treatment, yet I think it might with propriety be tried in cases of this kind that have been mentioned. 2d. Dupuytren ligatured the axillary artery under the pectoral muscles, for a case of subclavian aneurism, two arterial branches being divided in the incisions through the fat and cellular tissue, and the patient died on the ninth day. This is the only instance, to my knowledge, in which the distal operation has been attempted for the cure of this disease. It could not be expected to succeed; for between the ligature and the sac are the large and numerous alar, acromial, and thoracic branches of the axillary artery, which would continue to be fed by a current sent through the tumor, and thus preclude the possi- bility of its contents being sufficiently stationary for ultimate contraction and cure to result. Laugier performed the distal operation in a supposed case of subclavian aneurism, which afterwards turned out to be one of the brachio- cephalic artery. Ligature of the subclavian artery in the third part of its course, on the distal side of the tumor has been suggested, and may, perhaps, hold out some pros- pect of success in cases of aneurism situated between or internal to the scaleni. In an aneurismal sac springing from the artery in this situation, the principal current of blood would, in all probability, be that which is destined for the supply of the upper extremity. Some of the branches arising from the artery before it has passed beyond the scalenus anticus would, doubtless, be more or less compressed, and thus obliterated, by the tumor, or might be obstructed by an extension of the laminated fibrine over their orifices. If, therefore, the supply to the upper extremity could be cut off, there might be a possibility of those changes taking place within the sac which are necessary for the oblitera- tion of its cavity. The principal obstacles to this desirable result would ne- cessarily be the transversalis colli and humeri arteries; which, being the two vessels that are more particularly destined to carry on the circulation in the upper extremity after the ligature of the subclavian, would necessarily, if not occluded, undergo dilatation, and thus continue to draw too large a current of blood through the sac for stratification of its contents to take place; and if occluded, there would be danger of gangrene of the arm from insufficient vas- cular supply. These difficulties are met by a plan of procedure, the suggestion of which has originated, I believe, with Mr. Fergusson, but which has not, to my knowledge, been had recourse to as yet. It is, 3d, the amputation of the arm at the shoulder-joint, and then the distal ligature of the artery — a des- perate undertaking truly, but for a desperate disease it must be remembered, and one that has never yet, under ordinary surgical treatment, been cured. The artery might be ligatured before the amputation. " It is known," says 552 ANEURISM OF THE AXILLARY ARTERY. Mr. Fergusson, "that amputation at the shoulder-joint is generally a very successful operation; so far as this wound is concerned, then, there might be little to apprehend, but the effect on the tumor is not so easily foretold. Liga- ture of the axillary artery on the face of the stump might here be reckoned like Brasdor's operation, — yet there is a vast difference, for in the latter case the same amount of blood which previously passed towards the upper extremity, would still find its way down, and probably part of it would run through the sac; whereas, were the member removed, as the same quantity would no longer be required in this direction, the tumor might possibly be much more under the control of pressure. The value of such a suggestion remains yet to be tested, however, and it would be futile to reason upon it at present. It might be a judicious venture first to tie the axillary or subclavian under the clavicle, and then, if it were found that the aneurism still increased, ampu- tation might be performed, either immediately before or after the separation of the ligature." Were a case of aneurism of the subclavian artery internal to the scaleni, to present itself to me, the plan that I should adopt would be, first the employ- ment of pressure on the vessel on the distal side of the tumor, if practicable; should this not succeed, I would, if the disease were situated between, or inter- nal to the scaleni, ligature the artery in the third part of its course, and did that not succeed in checking the increase of the aneurism, perform amputation at the shoulder-joint as recommended by Mr. Fergusson. Should the aneurism occupy the artery after it has passed the scaleni, I would not attempt the ligature of the artery below the clavicle, as it is an operation, the result of which is not very satisfactory, and would not prevent a large current through the sac for the supply of the collateral circulation of the arm, but at once have recourse to amputation at the shoulder, and then ligature the vessel, as near as possible to the sac. It is true that even in this case the ligature would be below the branches that are given off under the pectoral muscles, but as the arm would be removed, they could not undergo any increase of activity for the supply of the collateral circulation of the upper extremity. ANEURISM OF THE AXILLARY ARTERY. This artery, though less commonly the seat of aneurism than other large vessels, such as those of the ham, the groin, and the neck, yet is sufficiently frequently diseased, owing partly to its situation; for its proximity to the shoulder-joint causes it to be subjected to the very varied, extensive and often forcible movements, of which that articulation is the seat; and partly to the artery being deficient in that support which would be afforded it by an invest- ing sheath, such as is commonly met with in arteries of corresponding magnitude. Amongst the most frequent causes of axillary aneurism, may be mentioned falls upon the shoulder or upon the outstretched hands, and in many cases the efforts made at reducing old standing dislocations; instances of which are re- corded by Pelletan, Flaubert, Warren, and Gibson; the head of the bone in these cases having probably contracted adhesions to the artery, in consequence of which the vessel was torn during the efforts at reduction. Axillary, like subclavian aneurism, occurs more commonly on the right than on the left side, and is met with in especial frequency amongst men; of 37 cases, only 3 have occurred in women. In axillary aneurism there are three sets of symptoms, attention to which will usually enable the surgeon to recognize the disease; these are, the existence of a tumor in the axilla, the pain that it occasions, and the affections that it gives rise to in the limb. The precise situation at which an aneurism of the axillary artery presents externally, will depend upon whether it springs from that portion of the vessel SYMPTOMS AND DIAGNOSIS OF AXILLARY ANEURISMS. 553 that lies above, beneath, or below the pectoralis minor muscle. If from above, it will appear as a tumor seated immediately below the clavicle and occupying the triangular space between the upper margin of the lesser pectoral and that bone; if it be lower down, it will raise the anterior fold of the axilla, being prevented extending much out of this space, by the dense fascia that stretches across from one side to the other. The tumor, which is at first soft and com- pressible, has a whizzing bruit, and its pulsations, which are expansile, may be arrested by pressure upon the subclavian artery, where it passes over the first rib. It usually increases with great rapidity, owing to the little resistance opposed by the loose cellular tissue in this situation, and most commonly extends downwards and forwards, causing the hollow of the axilla to disappear. In some rare instances, however, the tumor has been known to take a direction upwards under the lesser pectoral, and into the cellular interval above that muscle, or even underneath the clavicle into the acromial angle between it and the trape- zius. Such a course for the aneurism to take is fortunately rare, as it presents serious inconvenience in the ligature of the subclavian, and there is more than one instance on record in which the sac has been punctured in the attempt to pass the needle round this vessel. When the aneurism is seated high up, it not unfrequently happens that the clavicle is pushed upwards by the pressure of the tumor beneath it — a complication of considerable moment in reference to the operation, the difficulties of which are greatly increased by it. The pres- sure of the tumor may give rise to serious consequences upon neighboring parts; thus, it may occasion a carious state of the first and second ribs, and the compression of the brachial plexus of nerves will occasion pain and numbness in the upper extremity. In some cases the brachial artery beyond the tumor would appear to be obstructed, no pulsation being perceptible in it; and the compression of the axillary vein may occasion oedema of the hand and arm, with some diminution in the temperature of the limb, which, if the tumor attain a very, large size, may even amount to symptoms indicative of impending gangrene. The diagnosis of axillary aneurism is usually readily made; there being but two diseases with which it can well be confounded, viz. chronic enlargement and suppuration in the glands of the axilla, and pulsating tumor of the bones in this region. From glandular or other abscess, the diagnosis is generally easy; but I have seen some cases in which, pulsation being communicated to their contents by the subjacent artery, it was somewhat difficult to distinguish the nature of the tumor. Here, however, the history of the case and its speedy progress to pointing will indicate its true nature. From medullary tumor, or osteo-aneurism of the head of the humerus, the diagnosis is not always so easy, and there are at least two instances on record in which the subclavian artery has been ligatured for disease of this kind, on the supposition of its being an aneu- rism. In these instances it has, however, generally been observed that the tumor first made its appearance on the forepart of the shoulder, and not in the usual situation of axillary aneurism; that it was from the first firm, smooth, elastic, but nearly incompressible; and that although it presented distinct pul- sation, there was no true bellows sound, but rather a thrilling bruit perceptible in it. The most important diagnostic mark, perhaps, is the fact of these tumors forming a prominence in situations in which aneurisms of the axillary artery would not at first show themselves, as at the upper, outer, or anterior part of the shoulder. In more advanced stages, when the substance of the bone has undergone absorption, and its shell has become thin and expanded by the out- ward pressure of the tumor, there is often a dry, crackling, or rustling sound perceived on pressure, which is never met with in cases of aneurism. Treatment of axillary aneurism.— I am not acquainted with any instance in which an aneurism of the axillary artery, not arising from wound or injury, has undergone spontaneous cure, or been consolidated by constitutional treat- 554 ANEURISM OF THE AXILLARY ARTERY. ment. Nor is it probable that compression can ever be made applicable to aneu- risms in this situation, inasmuch as the pressure that is brought to bear upon the subclavian must necessarily at the same time influence the whole or the greater part of the brachial plexus of nerves, to such an extent as to be unen- durable by the patient. The ligature of the artery is, therefore, the surgeon's sole resource in the treatment of these cases. The part of the vessel universally selected for the application of the ligature is, in accordance with the Hunterian doctrines, that which lies on the first rib beyond the scalenus anticus muscle; this part presenting the advantage of being sufficiently removed from the seat of disease to insure the probability of the coats of the artery being in a sound state, of being by far the most accessible, and, when deligated, of allowing the collateral circulation by which the vitality of the arm is to be maintained, to remain uninjured. Notwithstanding these obvious advantages presented by the I ligature of the subclavian over that of the axillary artery — in other words, of performing Hunter's instead of Anel's operation for the cure of spontaneous \ axillary aneurism — there would appear to be a tendency in the minds of some surgeons, to advocate the latter instead of the former of these operations; and to substitute for one that offers the advantages that have just been mentioned, a procedure that is not only much more difficult in its performance, and that interferes with the collateral circulation, but that is practised upon a diseased part of the vessel, in dangerous proximity to the sac. Ligature of subclavian in third part of its course. — In order to apply a ligature to that portion of the subclavian artery which intervenes between the acromial edge of the scalenus anticus and the lower border of the first rib, the patient should be placed in a recumbent position, the arm depressed as much as possible, and the head turned somewhat to the opposite side. The integuments of the lower part of the neck should then be put on the stretch by being drawn downwards over the clavicle, and an incision about four inches in length made upon the bone through the integument, the superficial fascia, and the platysma. When tension is taken off the part, this incision will be found to traverse the base of the inferior triangle of the neck; a vertical inci- sion should then be made at right angles to and falling into the centre of the first, and the two flaps of integument and fascia should then be turned up. A quantity of loose cellular tissue will now be exposed, in which a venous plexus, and the lower end of the external jugular vein, will commonly be found. These vessels should be carefully avoided, and the cellular tissue dissected or scratched through with the point of a knife and a blunt probe; should any vein be wounded, a double ligature must be passed underneath it, or either end tied. If the transversalis colli or humeri arteries, as occasionally happens, should in- conveniently traverse this place, they must be drawn out of the way with a blunt hook. By the combined action of cutting and scratching through the cellular tissue, the external edge of the scalenus anticus is reached; this is the udirecting line" down which the finger is run until the tubercle of the first rib is felt. This is the guide to the artery, which will be found immediately above and a little behind it, covered, however, and bound down to the rib by a dense fascia. This must now be very carefully opened with the edge of the knife, and the needle passed from before backwards. In doing this, attention must be paid to the brachial plexus, situated above and behind the artery. There are several points in connection with this operation that deserve special attention. In the first place it is necessary that the shoulder should be depressed as far as possible, so as to bring the superior margin of the clavicle down. This is a matter of much importance; for if the clavicle be thrust upwards by the pressure of a large aneurism, the surgeon will have to find the artery at the bot- tom of a deep narrow wound, instead of on a comparatively plane surface. A case occurred to Sir A. Cooper, in which the attempt to ligature the subclavian artery for a large aneurism of the axilla was forced to be abandoned, in conse- LIGATURE OF THE SUBCLAVIAN. 555 quence of the clavicle being thrust up to too great a height to enable him to reach the vessel. The extent of the difficulty occasioned by this elevation of the clavicle must necessarily depend in a great measure upon the height at which the subclavian artery happens in any particular case to be situated in the neck. It is not uncommon to find it pulsating so high in the neck, that no amount of elevation of the clavicle by subjacent axillary aneurism could raise that bone above the level of the vessel. In the majority of cases, however, in 17 out of 25, as shown by Mr. Quain, in his work on the Arteries, it is either below the level of the bone, or but slightly raised above it; so that if the clavicle were thrust upwards and forwards, the vessel would be buried in a deep pit behind it. Dupuytren was of opinion that the artery coursed high in persons who were thin, with slender, long necks; whereas, in thick, short-necked persons, with muscular shoulders, it was deeply seated. I have often verified the truth of this observation both in dissection and in examining the pulsations of the vessel during life. In order to obviate the difficulty that has occasionally been expe- rienced in reaching the artery when thus buried behind an elevated clavicle, it has been proposed by Mr. Hargrave to saw through the bone. The most serious objection that can be raised against this practice is the fact of the clavicle being sometimes a part of the wall of the aneurism; but supposing the surgeon could satisfy himself that this was not the case, I cannot see any objection to this procedure, provided any very great and insurmountable diffi- culty presented itself in getting the ligature round the vessel without it. In passing the needle round the subclavian, care must be taken that some of the lower cords of the brachial plexus be not included in the noose, and indeed the mistake has more than once been committed of tying these nervous trunks instead of the vessel: thus, Mr. Liston, in the first successful case of ligature of the subclavian in this country, passed the thread round the lower nervous cord; but immediately perceiving his error, turned it to account by drawing aside the included nerve, and thus more readily exposing the artery. Dupuytren, in a case of aneurism of some years' duration succeeded, after an operation that lasted one hour and forty-eight minutes, and which he describes as the most tedious and difficult he ever attempted, in passing a ligature round the vessel, as he believed. After the death of the patient, which occurred from hemorrhage on the fourth or fifth day, the fourth cervical nerve alone was found included in the noose. In a case related by Porter, it is stated that the artery communi- cated such distinct pulsation to the inferior nervous trunk, that there was no means of ascertaining whether it was the vessel or not, except by passing the needle under it. In some cases, as has already been stated, the sac passes upwards below the clavicle into the inferior posterior triangle of the neck; when this is the case, the surgeon incurs the risk of puncturing it from its close proximity to the artery, as it lies on the first rib. This accident happened to Mr. Cusack while ligaturing the subclavian in the third part of its course, for a diffused aneurism of the axillary artery. An alarming gush of blood took place, which was arrested by plugging the wound, but the hemorrhage recurred on the tenth day, and the patient died. In a case related by Mr. Travers, in which the sac was punctured by the needle, which was being passed round the artery, the blood, which was arterial, did not flowjoer saltum, but in a continuous stream. "The hemor- rhage," says Mr. Travers, "was more terrific and uncontrollable than I have ever witnessed," and was not commanded by drawing the ligature tight. It was so great that it was doubtful whether the patient would leave the theatre alive, and was only arrested by plugging the wound with sponge-tents. The patient died of inflammation of the pleura. On examination, the aneurismal sac was found to have a pouch-like enlargement upwards, overlying the artery, where it had been punctured. If it be found that the sac encroaches upon the neck, rising above the clavicle, 556 aneurism of the axillary artery. or that the artery is not sound in the third part of its course, it may be neces- sary to ligature it between the scaleni, by dividing the outer half or two-thirda of the scalenus anticus. This operation should not be considered as one distinct from the ligature of the vessel in the third part of its course, but rather as an extension of that proceeding, if it be found, for the reasons just mentioned, un- advisable to tie the artery on the first rib; in this way it has been practised by Dupuytren and Liston. In its first steps, as far indeed as the exposure of the scalenus anticus, it is the same as that for the deligation of the vessel in the third part of its course. When this muscle has been exposed, a director must be pushed under it, upon which it is to be divided to the extent of half or two-thirds its breadth, when it retracts, exposing the vessel. ^ During this part of the operation, some danger may be incurred to the phrenic nerve, and the transversalis colli and humeri arteries; but if ordinary care be taken, this will not be very great. The phrenic nerve, as I have found by very frequent exami- nations on the dead body, lies altogether to the tracheal side of the incision, if that be not carried beyond one-half the breadth of the muscle; and should it appear to be in the way, may readily be pushed inwards towards the mesial line, being only loosely invested by cellular tissue. I have, however, seen one in- stance in which the right subclavian artery was ligatured for a spontaneous cylindriform aneurism of the axilla, and the patient died on the eighth day, of pneumonia; on examination after death, the edge of the scalenus was found cut, and the phrenic nerve divided. Had the pneumonia in this case anything to do with the injury to the nerve ? I do not think it improbable, as division of one phrenic by paralyzing to a certain extent the diaphragm, and so far inter- fering with the respiratory movements, must necessarily have a tendency to induce congestion of the lung, which would readily run on to inflammation of that organ. I have likewise heard of one case in which incessant hiccough fol- lowed this operation, and after death the phrenic nerve was found reddened and inflamed, having probably in some way been interfered with during the expo- sure of the vessel. Another important point in reference to the ligature of the vessel in this part of its course is the frequency with which a branch arises from the subclavian artery between the scaleni. When this peculiarity exists, there would probably be but a slender chance of the occlusion of the artery by ligature in this situa- tion. The transversalis colli and humeri arteries, though in some danger, whilst crossing over the scalenus anticus, may be avoided by keeping the incision in the muscle between and parallel to these vessels. One principal danger in ligatu- ring the subclavian artery at any point above the first rib, certainly arises from interference with the fine cellular tissue which lies between it and the scalenus muscles, separating it from the pleura, and which is continuous with the cellu- lar membrane of the anterior mediastinum, being indeed the deep portion of the ascending layer of what Sir A. Cooper has described as the " thoracic fascia," and which tends to form the superior boundary of the chest, being continuous in the neck with the deep cervical fascia. After the deeper layers of the cervi- cal fascia have been opened, this fine cellular membrane presents itself, and if inflammation be excited in it, the morbid action will readily extend by mere continuity of tissue into the thorax by the anterior mediastinum, invading ulti- mately the pleura and pericardium. Hence, whenever it is practicable, the surgeon should keep the point of the needle close to that part of the artery which lies upon the first rib, as there is less risk here of opening into the deep cellular tissue of the neck. The general result of the ligature of the subclavian artery in the third part of its course, for spontaneous aneurism in the axilla, is by no means satisfactory. Thus, of 47 cases of aneurism of the axillary artery, not dependent upon any external wound, in which the artery was ligatured above the clavicle, I find 23 cures against 24 deaths. This result is so unfavorable, and so different, indeed, LIGATURE OF THE SUBCLAVIAN. 557 from what I had anticipated, that I was led to analyze carefully the causes of death. I find them as follows: — Inflammation within the chest, &c......10 cases. Suppuration of the sac ...... 6 " Hemorrhage ......... 3 " Gangrene of hand and arm ..... 1 " General gangrene ........ 1 " Not stated.........3 " 24 « Thus it will be seen that the two most frequent causes of a fatal result fol- lowing the operation for axillary aneurisms, are not those that are usually met with after the ligature of the larger vessels. It would therefore appear to be owing to some special condition, dependent either upon the application of a ligature to the subclavian artery in the third part of its course, or upon the situation and nature of the disease for which that operation is had recourse to; and the important point to be determined is, whether these conditions are the accidental or the necessary consequences of the application of a ligature in this situation for the cure of aneurism in the axilla. The inflammation of the contents of the thorax proved fatal in 9 out of 22 cases, or 1 in 2-5, and is the most frequent cause of death, though not, I believe, the most frequent untoward complication of this operation. It might at first be supposed that in this respect the operations on the subclavian artery resembled other of the greater operations, after which pneumonia is so common a sequela; but on closer examination it will be found that this is not the case, that the inflammation, when attacking the thorax or its contents after ligature of this artery for axillary aneurism, is not confined to the lungs, but very commonly affects the pleura and pericardium as well as or even in preference to these organs. It would, therefore, appear probable that it arose from causes that are essentially connected with this disease or operation. These are referable to three heads. 1st. Inflammation of the deep cellular tissue at the root of the neck, extend- ing to the anterior mediastinum, the pleura and pericardium. This would ap- pear to have been the cause of the supervention of inflammation in a patient of Mr. Key's, and has been especially adverted to by that excellent surgeon in the relation of the case of a patient on whom he performed this operation. 2d. The sac may, by its pressure inwards, encroach upon and give rise to inflammation of that portion of the pleura that corresponds to its posterior aspect. This occurred in a case in which Mr. Mayo, of Winchester, operated, and is more liable to happen if suppuration has taken place in the sac; when this happens, adhesion may take place between it and the pleura, or even the tissue of the adjacent lung, and the contents of the suppurated tumor be dis- charged into the pleural cavity or air-tubes, and so coughed up. Of this curi- ous mode of termination there are at least two cases on record, one by Mr. Bullen, in which the patient recovered; the other by Dr. Gross, in which the patient died from the escape of the contents of the sac into the cavity of the pleura. 3d. Division of the phrenic nerve would necessarily, by interfering with the respiratory movements, induce a tendency to congestion and inflammation of the tissue of the lungs; and although such an accident must be a very rare one in cases of ligature of the subclavian for axillary aneurism, yet it undoubtedly has occurred, as I have myself witnessed in one case. Suppuration of the sac is the most common, though not the most fatal acci- dent after ligature of the subclavian for spontaneous axillary aneurism. It was the immediate cause of death in 6 cases, and occurred in 2 of the patients that 558 ANEURISM OF THE AXILLARY ARTERY. died of inflammation of the chest; and took place in 6 cases that recovered, in all 14 cases out of 45, or nearly 1 in 3, a much higher proportion than is gene- rally observed in cases of ligature for aneurism. What is it that occasions this greater frequency of suppuration of the sac in these than in aneurisms in other situations? The only cause to which it appears to be attributable is the great laxity of the cellular membrane in this situation, which allows the tumor to increase so rapidly in size as to excite in- flammatory action in the surrounding tissues, which may speedily run into sup- puration. So long as the contents of the tumor continue fluid, they will neces- sarily excite less irritation on surrounding structures; but when once they have become solidified, whether by the gradual deposition of laminated fibrine, dur- ing the progress of the disease, or more suddenly, in consequence of those changes that take place in the contents of an aneurismal sac after the ligature of the artery leading to it, the indurated mass acting like any other foreign body sets up inflammation in the cellular tissue that is in immediate contact with it, and thus disposes it to run into suppuration. The more speedily the solidifica- tion takes place, the more disposition will there be to the occurrence of this accident, the neighboring parts being unable to accommodate themselves to the sudden extension and compression they are compelled to undergo. The period at which suppuration of the sac may be expected to occur in cases of axillary aneurism, after the ligature of the subclavian, must necessarily in a great measure be dependent on the state of the sac at the time of the operation. If inflammatory action have already set up around it, it may happen in a few days after the artery has been tied. But if this morbid action have not already commenced, the period at which suppuration may most probably be expected is between the first and second month. The period at which suppuration and rupture of the sac take place does not influence the probable termination of the case to any material extent; as in the cases that proved fatal, death occurred at various periods between the seventh day and the second month; in Aston Key's case, on the ninth day, in Mayo's, on the twelfth, in Belardini and Graefe's, at the end of the first month, in Rigaud's at the sixth week, in B. Cooper's in the second month. The recoveries, likewise, took place at all periods after the ligature of the vessel, between a few days, as in Porter's, and six weeks, as in Halton's case. An axillary aneurism that has suppurated may either burst externally or into the lungs or pleura, or both. It is most usual for it to burst externally; the tumor enlarging, with much pain and tension, a part of the skin covering it becomes inflamed, fluctuation can here be felt, and if an incision be not made into it, it will give way, discharging most usually a quantity of dark-colored pus, mixed up with more or less broken down and disintegrated coagulum and fibrinous deposit, and perhaps sooner or later followed by a stream of arterial blood. Occasionally, but more rarely, the sac extending backwards becomes adherent to the pleura, and may give way into that cavity, or by pressing upon, may become incorporated with the lungs. Of this remarkable termination, two instances are recorded, in one of which recovery took place. The first case of the kind is one in which Mr. Bullen ligatured the subclavian artery for axillary aneurism. Eighteen days after the operation the tumor began to increase, and to take on the symptoms that are indicative of suppura- tion. On the twenty-sixth day six or eight ounces of bloody pus were expecto- rated during a paroxysm of coughing, and the tumor suddenly diminished to one-half its size; it was now punctured, and five ounces of the same kind of matter let out with great relief. When the patient coughed, air passed into and distended the sac through an aperture between the first and second ribs, near their sternal extremities, through which the contents of the tumor had escaped into the lung. The discharge from the external aperture greatly decreased, ACCIDENTS AFTER LIGATURE OF THE SUBCLAVIAN. 559 the cough lessened, and finally, three months after the operation, the patient was quite well. Dr. Gross tied the subclavian artery for axillary aneurism on the 18th of February. After the performance of the operation the contents of the tumor solidified, and its volume progressively diminished. On the 15th of March, the patient suffered from fever, and slight tenderness on the apex of the tumor was perceptible. On the 16th, he was suddenly seized with intense pain in the chest, which was particularly severe at the base of the right lung, and extended up towards the axilla. The respiration throughout the right lung was bron- chial, and there was dulness on percussion over the lower ribs; the aneurismal tumor had suddenly disappeared at the time of the attack. On the 18th, the patient experienced a sensation, as if a fluid was passing from the pleuritic cavity into that of the aneurismal tumor; and, upon auscultating, a plashing sound was heard at every inspiration, the noise resembling that produced by shaking water in a closed vessel. On the 20th he died. Upon dissection the aneurism was found to communicate by an aperture, one inch and three- quarters in length, by an inch and a half in width, with the pleural cavity; this opening was situated between the first and second ribs, and was obviously the result of ulceration and absorption, caused by the pressure of the tumor. Both ribs were denuded of their periosteum. The right side of the chest con- tained nearly three quarts of bloody serum, intermixed with laminated clots and flakes of lymph; the former of which had evidently been lodged originally in the aneurismal sac (Norris, in American journal, 1845, p. 19). Besides these cases, a somewhat similar one has been recorded by M. Ncret, of Nancy. A patient was admitted into the hospital, laboring under hemoptysis, and on examination was found to have an aneurism of the left subclavian artery as large as a chestnut. He died shortly after admission, and on examination the aneurism was found to communicate with a large cavity in the upper part of the lung. The cause of death in Dr. Gross' case was probably the fact of the sac opening and discharging its contents into the pleural cavity. This does not appear to have occurred in Mr. Bullen's, in which a communication was esta- blished directly with the lung, the contents of the abscess finding exit through the air-tubes, as is the case, occasionally, in hepatic abscess, adhesion having previously taken place between the opposed surfaces of the pleura. The principal danger, and the most frequent cause of death after the suppu- ration of the sac, is the supervention of profuse arterial hemorrhage. This may either occur from the distal extremity of the artery opening into the sac, or from one of the large branches which serve to support the collateral circulation round the shoulder, such as the subscapular or posterior circumflex, coming off either immediately above or below the sac, or from the sac itself. When hemorrhage does not take place after the suppuration of the sac, it must be from the fortunate circumstance of the occlusion of the main trunk, where it opens into the tumor. It can scarcely be from the occlusion of the principal collateral branches, as there would, in this event, be a difficulty in the preser- vation of the vitality of the limb. It is easy to understand, that if the sac sprint from the axillary, at a little distance above the orifices of the subscapular and circumflex arteries, all that portion of the main trunk which intervenes between the tumor and these vessels might be occluded, and thus hemorrhage be prevented on suppuration taking place; whilst the collateral circulation would take place uninterruptedly through these vessels. If this portion of the artery have not been occluded by inflammatory action, the safety of the patient must depend upon the accident of a coagulum or piece of laminated fibrine being fixed or entangled in the mouth of the sac. This may prevent for a time the escape of arterial blood, which, on such a plug being loosened, may break 560 ANEURISM OF THE AXILLARY ARTERY. forth with impetuosity, and either at once, or by its recurrence at intervals, carry off the patient. Another danger may be superadded in these cases on the suppuration of the sac and the supervention of hemorrhage, namely, the occurrence of inflamma- tion of the pleura, lung, and pericardium, from the extension inwards of the morbid action going on in the sac. Secondary hemorrhage does not frequently occur in cases of ligature of the subclavian artery in the third part of its course, except as a consequence of suppuration of the sac. I am only acquainted with two cases in which it proved fatal from the hemorrhage taking place from this artery at the part ligatured. One of these happened to Liston, and the preparation is preserved in the Museum of the College of Surgeons (No. 1695). In this case, it may be seen that the artery was diseased at the point ligatured, and that the bleeding occurred, as usual, from the distal side of the ligature. ^ Gangrene of the hand and arm is but seldom met with as a sequela of the operation we are considering. This is doubtless owing to the freedom of the anastomosing circulation between the branches of the transversalis colli and humeri, and those of the subscapular, circumflex, and thoracic acromial arteries; as well as between the superior thoracic and the branches of the first and second intercostals and internal mammary, by which the vitality of the limb is readily maintained. The principal risk from gangrene would doubtless arise from the subscapular artery being in any way occluded or implicated in the disease, as it is on the anastomosis of this vessel that the limb is mainly depend- ent for its supply of blood. But, at all events, this danger is small, the only case in which it appears to have given rise to a fatal termination being one in which Mr. Colles tied the artery; gangrene of the limb coming on after much constitutional disturbance of a low type, with rapid, weak pulse, thirst, sweats, restlessness, and delirium. In Blizard's case, there was sloughing of the sac, and pericarditis, the gangrene being confined to two fingers; and in Brodie's case, it occurred in both the lower as well as in the upper extremity, and must, therefore, have proceeded from some constitutional cause, altogether independent of the mere arrest of circulation through the subclavian. The case of an axillary aneurism becoming inflamed, and threatening to run into suppuration before the surgeon has had an opportunity of ligaturing the subclavian artery, is one that is full of important practical considerations, and one that admits of little delay, for if the sac rupture, or be opened, fatal hemorrhage is the necessary and inevitable result. It would obviously be impossible, in a case of spontaneous aneurism, with any fair chance of success, to lay open the tumor, turn out the coagula, and ligature the vessel above and below the mouth of the sac; the coats of the artery being not only diseased, but still further softened by inflammation and supervening suppuration, would not be in a condition to hold a ligature. There are two other courses open, viz., the ligature of the vessel, or amputation at the shoulder-joint, and in the selection of one or other of these, the surgeon must be guided by the progress the disease has made, the condition of the limb as to circulation and temperature, and whether the contents of the tumor are solid or fluid. If the tumor be of a moderate size, and circumscribed, the arm of a good temperature, and not very cedematous, the ligature of the artery may hold out a reasonable chance of success. It is true that this is but a chance; for as the blood will, immediately after the noose is tied, be carried by the supra and posterior scapular arteries into the subscapular and circumflex, and by them into the axillary at no great distance from the mouth of the sac, or enter, perhaps, directly into the mouth of the latter if the profunda or circumflex should chance to take their origin from the dilated portion of the vessel, the only safeguard against the supervention of hemorrhage as soon as the sac has burst or been opened or has discharged its contents, will be the occlusion by LIGATURE OF THE AXILLARY ARTERY. 561 inflammatory action of that portion of the artery that intervenes between these two collateral branches and its mouth, or the accidental entanglement in the latter of a mass of laminated fibrine. Yet under the circumstances, as to the condition of tumor and limb that have just been mentioned, it would be but right for the surgeon to give the patient a chance of preserving his limb. Should, however, hemorrhage occur on or after the discharge of the contents of the sac, the subclavian having previously been ligatured, what should be done ? If the bleeding be moderate, an attempt should be made to arrest it by plugging the wound, and by the application of a compress and bandage. If it recur, or is so profuse as to threaten the life of the patient, what course should the surgeon then pursue ? Two lines of procedure are open to him: either cutting through the pectoral muscles so as to lay the sac open fully, and attempting to include the bleeding orifice between two ligatures, or amputation at the shoulder-joint. If a surgeon were to undertake the first of these alternatives in a case of spontaneous aneurism, of which alone we are now speaking, he would, in all probability, find the part in such a condition as would prevent the possibility of his completing the operation he had commenced. After laying open a large sloughing cavity, extending under the pectoral muscles, perhaps as high as the clavicle, and clearing out the broken-down coagula and grumous blood it con- tains, in what state would he find the artery ? Certainly, the probability would be strongly against its being in such a condition as to bear a ligature, even if it could be included in one. Its coats, in the immediate vicinity of the sac, could not, in accordance with what we know to be almost universally the case in spontaneous aneurisms of large size or old standing, be expected to be in anything like a sound, firm state, and would almost certainly give way under the pressure of the noose; or the vessel might have undergone fusiform dilata- tion, as is very common in this situation, before giving rise to the circumscribed false aneurism, in which case it would be impossible to surround it by a ligature; or, again, the subscapular or circumflex arteries might arise directly from, and pour their recurrent blood into the sac or the dilated artery, and lying, as they would, in the midst of inflamed and sloughing tissues, no attempt at including them in a ligature could be successfully made. Under such circumstances as these, the danger of the patient would be considerably increased, by the irrita- tion and inflammation that would be occasioned by laying open and searching for the bleeding vessel in the sac of an inflamed, suppurating, and sloughing aneurism, and much valuable time would be lost in what must be a fruitless operation; at the close of which it would, in all probability, become necessary to have recourse to disarticulation at the shoulder-joint, and thus remove the whole disease at once. I should, therefore, be disposed to have recourse to disarticulation at the shoulder-joint at once, in all cases of profuse recurrent hemorrhage, following sloughing of the sac of an axillary aneurism, which could not be arrested by direct pressure on the bleeding orifice, after the subclavian has been tied. There is another form of axillary aneurism that requires immediate amputa- tion at the shoulder-joint, whether the subclavian artery have previously been ligatured or not; it is the case of diffuse aneurism of the armpit, with threatened gangrene of the limb. Ligature of the axillary artery. — Should ligature of the axillary artery at any time be required, the vessel may be secured in two ways, in the space that intervenes between the lower margin of the clavicle and the fold of the axilla. The first is by an incision, either straight or somewhat semi-lunar, parallel to and immediately below the inferior border of the clavicle; this must be carried through the pectoral muscle, and when this is divided, some loose cellular tissue, in which the thoracica suprema artery ramifies, is exposed. 36 562 ANEURISM OF THE FORE-ARM. This must be scratched through cautiously, until the fascia covering the vessels is reached. On opening this, which must be done in the most careful manner, by making a small aperture in it and then passing a grooved director under it, the vein first comes into view. This must be drawn downwards, when the artery will be found immediately above and behind it in the deep hollow formed by the clavicle above, and the edge of the lesser pectoral below. This opera- tion is an exceedingly difficult one, on account of the depth and narrowness of the wound and the muscular character of its walls, as well as from the embar- rassment occasioned by the numerous venous and arterial branches which ramify across the space in which the artery lies. After the vessels have been exposed, the passage of the ligature around them will be greatly facilitated by bringing the arm to the side of the body, so as to take off all tension in the wound. The safer and simpler operation consists in making an incision from the centre of the clavicle directly downwards, in the course of the vessels, to the middle of the anterior fold of the axilla. In this way the skin, superficial fascia, and pectoralis major must be successively divided. The lesser pectoral will then be exposed, and the artery may either be ligatured below this, without further division of muscular substance, or if it be thought desirable to deligate it under this, the muscle must be cautiously cut through. When this is done a very distinct and firm fascia will come into view; this, being pushed up, must be carefully opened, when the artery and vein will be seen lying parallel to one another, the artery not being overlapped by the vein, as it is higher up. The vein having been drawn inwards, the aneurismal needle must be carried from above downwards between it and the artery. The great advantage of this operation is, that the wound is open and free, and that, con- sequently, the artery can be more readily reached in any part of its course. The disadvantage is the great division of muscular substance that it entails. This, however, need not leave any permanent weakness of the limb, as by proper position ready and direct union may be effected between the parts. ANEURISM OF THE ARM, FORE-ARM, AND HAND. Spontaneous aneurism rarely occurs below the axilla, but yet it may occa- sionally be met with at any part of the upper extremities. Thus Palletta, Flajani, Pelletan, and others, relate cases of spontaneous aneurism at the bend of the arm; and Liston states that he once tied the brachial artery in an old ship-carpenter, who, whilst at work, felt as if something had snapt in his arm. Mr. Pilcher has recorded a case of aneurism under the ball of the right thumb, which was produced by repeated though slight blows with the handle of a hammer used by the patient, a working goldsmith, in his trade; the radial and ulnar arteries were tied immediately above the wrist, and the disease thus cured. Aneurism has also been met with in this situation after attempted reduction of the thumb. Spontaneous aneurism in the fore-arm is of extremely rare occurrence. I am only acquainted with one, that recorded by Mr. Todd, as occurring in a woman twenty-eight years of age, which had existed for several years before the brachial was ligatured, when pulsation in the tumor ceased, though it continued solid and hard for some months after the ope- ration, and in 1849, a man was admitted into University College Hospital, for a tumor that presented all the characters of aneurism, and that was situated in the upper third of the ulnar artery of the right fore-arm. The brachial was ligatured by Mr. Arnott, when pulsation and bruit ceased in the tumor, though some enlargement of the arm continued for some time afterwards. Rare as spontaneous aneurisms are in these situations, the traumatic forms of the disease are, as has already been stated (page 178), of frequent occurrence, ANEURISM OF THE ARM, FORE-ARM, AND HAND. 563 and may require the ligature of the brachial, or of either of the arteries of the fore-arm. In cases of aneurism in this situation, direct pressure might be tried with advantage, provided they are of small size and unattended by inflammation of the superjacent integuments. Compression to the trunk of the artery above the tumor is rarely applicable on account of the pain that is induced by the pressure upon the neighboring nerves which cannot be isolated from the artery. Ligature of the brachial artery.—The brachial artery may be ligatured in the middle of the arm, which is considered the seat of election of this operation, by making an incision about three inches long, parallel to and upon the inner edge of the biceps, which is the " directing line;" the fascia, which is exposed, must be opened carefully to a corresponding extent, when the median nerve will commonly be seen crossing the wound; this must be drawn downwards with a blunt hook, when the artery, accompanied by its two veins, will be exposed; these vessels must then be separated from one another, and the ligature passed and tied in the usual way. In performing this operation the principal point to attend to is to cut down upon the inner edge of the biceps, which will be the sure guide to the artery. If the surgeon keep too low, he may fall upon the ulnar nerve and the inferior profunda artery, which might possibly be mistaken for the brachial; but by taking care to expose the lower fibres of the biceps in his early incision, he will avoid this error. In the upper part of the arm, the brachial artery, where the axillary termi- nates in it, will be found lying immediately behind, and covered by its vein. On drawing this to the inner side, the artery will be seen, the plexus of nerves being somewhat above and behind it. In ligaturing the artery in this situation, care must be taken to divide the integuments, which are extremely thin, with great caution; when by rotating the arm outwards and bending the elbow, the artery will be thrown forward and rendered less tense, so that a ligature can easily be passed around it. At the bend of the arm, the brachial artery may be reached by making an incision about two inches in length in a direction downwards and inwards, about half an inch internal to the edge of the tendon of the biceps. After carrying it through the skin and fascia, the vessel will be found accompanied by its veins, in the triangular space bounded externally by the biceps tendon, and internally by the pronator teres. In performing this operation, the veins at the bend of the arm, with the filaments of the internal cutaneous nerve, must be divided to some extent, though they should be spared as much as pos- sible. The artery will be found about half an inch to the inner side of the tendon, accompanied by the median nerve, which is to its ulnar side. The radial and ulnar arteries should never, I think, be ligatured above the middle third of the arm except in cases of direct wound; any attempt at deli- gating them at the upper part of the fore-arm, will not only be attended with great difficulty, but with the danger of crippling the muscles in this situation, and thus impairing the after movements of the arm, and may always have the ligature of the brachial substituted for it. The radial artery may be ligatured near the wrist, by making an incision about two inches in length, half an inch to the outside of the tendon of the flexor carpi radialis, the "directing line;" when, after the division of the super- ficial and deep fascia, the artery, accompanied by its two veins, will be exposed, and may be tied in the usual way. The ulnar artery above the wrist, may be readily ligatured by making an incision about two inches in length, a little above, and one-third of an inch to the radial side of the pisiform bone, parallel to the tendon of the flexor carpi ulnaris, which is the "directing line" to the vessel. After dividing the fascia covering it, the artery, with its two accompanying veins, will be found to the radial side of the ulnar nerve. 564 ANEURISM BY ANASTOMOSIS, AND NEVUS. CHAPTER XXXIX. ANEURISM BY ANASTOMOSIS, AND NEVUS. Aneurism by anastomosis, is a disease of the arteries, in which the vessels become excessively elongated, tortuous, and serpentine; sometimes they assume a varicose condition, being dilated into small sinuses, and are always very thin- walled, resembling rather veins than arteries in structure. This kind of dilata- tion of the vessels will give rise to pulsating tumors, often of considerable size, and of a very active and dangerous character. They may be situated in almost any tissue or organ of the body, but are most commonly met with in the sub- mucous and subcutaneous cellular tissue, and most frequently occur in the upper part of the body, especially about the scalp, orbit, lips, and face; but they have been met with in other situations, such as the tongue, and even in internal organs, as the liver, and I have seen very active growths of this kind on the nates and foot. In some cases, aneurism by anastomosis occurs in bones, in which it forms a special disease, and is not uncommonly associated with enceph- aloid. Indeed, there is certainly a great tendency for aneurism by anastomosis and encephaloid to run into one another, the limits between them not being very clearly defined, especially when occurring in connection with osseous tissue. It will generally be found that the arteries leading to, though at a considerable distance from the aneurism by anastomosis, are tortuous, enlarged, with thin and expanded coats, and pulsate actively; in fact, constituting that condition that goes by the name of cirsoid dilatation of the vessels. Aneurism by anastomosis forms tumors of varying magnitude and irregular shape; they are usually of a bluish color, have a spongy feel, are readily com- pressible, not circumscribed, and with large tortuous vessels running into and from them on different sides. Their temperature is generally above that of neighboring parts; and a vibratory or purring thrill, amounting in many cases to distinct pulsation, may be felt in them. This pulsation or thrill is synchro- nous with the heart's beat, may be arrested by compressing the tumor or arteries leading to it, and returns with an expansive beat on the removal of the pressure. The bruit is often loud and harsh, but at other times of a soft and blowing character. These growths rarely occur in infancy, but generally make their appearance in young adults, though they may be met with at all periods of life, and often as the consequence of an injury of some kind. It is of importance to effect the diagnosis between ordinary aneurism and that by anastomosis. In many cases the situation of the tumor at a distance from any large trunk, as on the scalp, the outside of the thigh, or the gluteal region, will determine this. Then again the outline of the growth is less distinct than in true aneurism; and tortuous vessels will be felt leading to it from different directions. The swelling also is doughy, and very compressible; but when the pressure is removed, the blood enters it with a whizz and thrill, not with the distinct pulsating stroke that is found in aneurism. The pulsation, not so forcible as in aneurism, is more heaving and expansive. The bruit is louder, more superficial, sometimes having a cooing note. By pressure on the arteries leading to the tumor, these signs are usually not entirely arrested, though diminished in force, the blood entering it from the neighboring parts, and in a less direct way. The treatment of aneurism by anastomosis must depend upon the size and situation of the growth. When it is so placed that it can be ligatured or ex- cised, as on the lip, or when of small size, about the neck, face, or scalp, it should be removed in one or other of these ways. I always prefer, in cases of nevus, the ligature applied, as will immediately be described, as being the safest, NEVUS. 565 and upon the whole the readiest mode of getting rid of such a tumor. If ex- cision be practised, it is necessary to be very careful to cut widely of the disease; if it be cut into, fearful hemorrhage may ensue, which can only be arrested by pressure, and which in several instances has proved fatal. If the disease be very large and extended, as is commonly seen on the scalp, or when deeply seated, as on the orbit, neither ligature nor excision of the tumor can be practised, and it becomes necessary to starve it by cutting off its supply of blood. This may be done either by ligaturing the principal branches leading to it, or the main trunk of the limb or part. The simple ligature of the arterial branches leading to the tumor has never, I believe, been followed by success, at least in 10 recorded instances in which it has been had recourse to, the disease has not in one instance been cured. It has, however, been success- fully conjoined by Dr. Gibson, in 2 cases of aneurism by anastomosis of the scalp, with incisions made round the tumor at intervals between the principal feeding arteries, which at the same time were tied. The main trunk leading to the tumor has been ligatured in a considerable number of cases. The brachial and femoral arteries have been tied for disease of this kind situated on the extremities, and in some instances with success; but the carotid is the vessel that has been most frequently deligated in conse- quence of the tumor being so commonly situated on the scalp and in the orbit. This operation has been done in 20 recorded cases, and in 5 instances both the carotids were ligatured at intervals of several weeks. In all of those cases in which the double operation was performed, the patients ultimately recovered. In some of the cases in which one carotid alone was tied, the disease being seated upon the scalp, was not cured, and it was afterwards found necessary to have recourse to ligature of the tumor, to excision, and to other means of removal; indeed, when seated upon the scalp, this disease appears to be more intractable than in any other part of the body, owing probably to the freedom of the arterial supply from the numerous vessels that ramify in this region. Here, however, much benefit might be derived after ligature of the carotid, by adopting the plan suggested by Dr. Gibson, of tying the feeding arteries, and making incisions between them down to the bone. The ligature of the carotid has answered best for diseases of this kind in the orbit; of 6 instances in which the artery has been tied for aneurism by anastomosis in this situation, in 5 a cure was accomplished. NEVUS. This disease, under which those various affections are included, termed mother's marks, erectile tumors, and vascular growths, constitutes an important and interesting section of surgical affections. It appears to consist essentially in an excessive development of the vascular tissue of a part, and differs greatly as to nature, cause, and treatment; according as the arterial, the capillary, or the venous elements of the tissue predominate. The predominance of the arte- rial tissue we have already considered, under the head of aneurism by anasto- mosis, it now remains for us to describe the capillary and venous nevi. Capillary nevi appear as slightly elevated but flat spots on the skin, of a bright red or purplish tint, and having occasionally granular or papillated elevations, with some larger vessels ramifying on their surface. They often spread super- ficially to a considerable extent; they are usually situated on the face, head, neck, or arms, but occasionally, though more rarely, on the back, the nates, the organs of generation, and the lower extremities; they are, I believe, always con- genital, though often at birth of a very small size, not larger than a pin's head, from which they may spread in the course of a few weeks or months to patches an inch or two in diameter. In many cases no inconvenience results from this disease, except the deformity it entails, but occasionally, more especially when 566 ANEURISM BY ANASTOMOSIS, AND NEVUS. the growth is at all prominent, there is a great disposition to ulceration of an unhealthy and hemorrhagic character. When bleeding occurs, it is usually in a trickling stream, and without any degree of force. Venous nevi are of a dark purple or reddish color, usually very prominent, and often forming distinct tumors of considerable size, which may either be smooth and ovoid, or else somewhat lobulated. On compressing a growth of this kind, it subsides to a certain extent, feeling doughy, soft, and inelastic, and on the removal of the pressure fills up again. In some cases, when consolidated by inflammation, or containing cysts, it cannot be lessened in bulk by pressure. These nevi are usually about the size of half a walnut, but sometimes much larger. I have removed them from the nates and the back fully as large as an orange. They less frequently occur upon the head and face than the capillary form of the disease; most of the instances that I have seen have been met with in the lower part of the body, about the nates, back, lower extremities, and organs of generation. Subcutaneous nevi are occasionally met with, of a mixed character, forming soft, doughy, and compressible tumors, which may be recognized by being capable of diminution by pressure, on the removal of which they slowly fill out again to as large a size as before; they also become distended when the child screams or struggles, and are usually of an oval shape, smooth, and uniform. The skin covering the tumor is often unaffected ; at other times it is implicated in an oval patch on the most prominent part of the growth, and occasionally the surround- ing veins are bluish and enlarged. In structure, the capillary nevi appear to be composed of a congeries of small tortuous vessels, of a capillary character; the venous nevi appear made up of thin tortuous veins, dilated into sinuses and small pouches. In the midst of these masses, cysts are not uncommonly found, sometimes con- taining clear, at other times, a dark, sanguinolent fluid. These cysts are probably venous sinuses, the openings into which have become occluded. The treatment of nevi may be conducted on three principles. 1st, by means calculated to excite adhesive inflammation in them, and so to produce plugging and obliteration of the vas- cular tissue of which they are composed; 2d, by agents that de- stroy the growth; and 3d, by removal with the knife or ligature. Each of these different plans of treatment is peculiarly appli- cable when the disease assumes certain forms, and affects certain situations. ^ 1st. When the disease is of small size, and occurs in such situations that its destruction by caustics, or removal by knife or ligature, would be attended by serious deformity, as when it is seated about the eyelids, upon the tip of the nose, at the inner angle between the eye and the nose, or about the corners of the mouth, it is best to endeavor to procure its obliteration, by ex- citing the adhesive inflammation in it. This may be done in various ways. If small, the nevus may be vaccinated. If larger, the most convenient plan consists, perhaps, in passing a number of fine silk threads across the tumor in different directions, and leaving them in for a week or two at a time, until they have produced sufficient inflammation along their tracks, then with- drawing them, and passing them into other parts of the tumor. In this way its consolidation may gradually be effected. Another very useful plan is to break up the substance of the growth sub- cutaneously, by means of a cataract needle, or tenotome, and in the intervals between the different introductions of this instru- ment to keep up pressure upon it. In other cases, again, passing acupuncture LIGATURE OF NEVUS. 567 needles into it, and then heating them by means of a spirit-lamp, or injecting the perchloride of iron into it by means of a small glass syringe with a screw- piston rod and a fine sharp-pointed nozzle (fig. 192), will induce the requisite amount of inflammation. In all these different ways the surgeon may succeed in curing the disease. 2d. When the nevus is small, very superficial, of the capillary character, with an exceedingly thin covering of cuticle, and so situated, as upon the arm, neck, or back, that a moderate amount of scarring is of little consequence, it may most conveniently be removed by the free application of nitric acid. This should be well rubbed on by means of a piece of stick, and after the separation of the slough produced by it, its application must be repeated as often as there is any appearance of the granulations springing up, which will occasionally happen at one angle of the wound, and is indicative of a recurrence of the vascular growth. 3d. When the nevus is of large size, constituting a more or less distinct tumor, and is of a somewhat venous character, it may occasionally be excised. In doing this, however, care should be taken to cut wide of the disease, and no operation with the knife should be undertaken unless the growth be either so situated, as upon the lip, that the parts may readily be brought or compressed together, or upon the nates or thigh, and of a very indolent and venous character. As a general rule, it is far safer, and more convenient, to extirpate the growth with the ligature, and this, indeed, is the mode of treatment that is most generally applicable to tumors of this kind in whatever situations they may occur, as it effectually removes them without risk of hemorrhage, and leaves a sore that very readily cicatrizes. The ligature requires to be applied in different ways, according to the size and situation of the tumor. In all cases, the best material for this purpose is firm, round, compressed whip- cord. This should be tied as Fie. 193. tightly as possible, and knot- ted securely, so that there may be no chance of any part of the tumor escaping complete and immediate strangulation. It is well, if possible, not to include in the noose any healthy skin, but to snip across with a pair of scissors that portion of integument which intervenes between the cords that are tied together; at the same time care must be taken to pass the ligatures well beyond the limits of the disease. When the tumor is small, an ordinary double ligature may be passed across its base, by means of a common suture needle, and the noose being cut and the thread tied on either side, strangula- tion will be effected. When of larger size, and of round shape, the most con- venient plan of strangulating the tumor is that recommended by Liston. It consists in passing, by means of long nevus-needles, fixed in wooden handles, and having the eye near their points, a double whipcord ligature, in opposite directions across the tumor; then cutting through either noose, and tying together the contiguous ends of the ligature until the whole of the growth is encircled and strangled by them. In doing this, a few precautions are necessary : thus, the 568 ANEURISM BY ANASTOMOSIS, AND NEVUS. first nevus-needles should be passed across the tumor unarmed (fig. 193 a), and used to raise up the growth somewhat from subjacent parts. The second needle armed (fig. 193 b), as represented in the annexed wood- Fia. 194. cut, carrying the whip-cord ligature by means of a piece of suture silk, should be passed across the tumor in the opposite direction to, but underneath the first needle; the needle (h) being withdrawn, the ligature is carried across, and the first one having been armed in the same way, carries its noose through the tumor as it is drawn out. The two nooses having then been cut, an assistant must seize, but not draw upon six of the ligature ends; the surgeon then having divided the intervening bridge of skin, ties pretty tightly, in a reef-knot, the two ends that are left hang- ing out; as soon as he has done this, he proceeds to the next two, and so on until he gets to the last (fig. 194). When he ties these, he must do so with all his force, especially if the tumor is large, as by drawing on them he tightens all the other nooses, and drags the knots towards the centre of the growth, which is thus effectually strangled. He then cuts off the tails of the ligature. After the tumor has sloughed away, which happens in a few days, if properly and tightly strangled, the sore is treated on ordinary principles. If the nevus is altogether subcutaneous, the skin covering it should not be sacrificed, but being divided by a crucial incision, may be turned down in four flaps, and the ligature then tied as directed. In some situations, as in the ante- rior fontanelle, it may be dangerous to pass the threads across the base of the tumor, lest the membranes of the brain which lay immediately beneath it be wounded. This difficulty I have readily overcome, by making a puncture on one side of the tumor, and then pushing an eyed-probe conveying the whip-cord across its base through the soft spongy tissue of which it is composed, and cut- ting down upon its point, where it projects on the opposite side of the tumor drawing it through; the second threads are tied in the same way, and the mass firmly strangulated. Although I have seen convulsions follow the ligature of nevi in this situation, I have never met with a fatal result. In some cases, the nevus is so flat and elongated that the application of the quadruple ligature, as above described, cannot include the whole of it. Under Fia. 195. Fig. 196. these circumstances, I have found the ligature about to be described eminently useful, having successfully employed it in a great number of instances. Its great advantage is, that while it completely and very readily strangles the LIGATURE OF NEVUS. 569 tumor, it does not inclose an undue quantity of integument, and thus does not produce a larger cicatrix than is necessary for the eradication of the disease. It is applied in the following way :—a long triangular needle is threaded on the middle of a whip-cord about three yards in length; one half of this is stained black with ink, the other half is left uncolored. The needle is inserted through a fold of the sound skin, about a quarter of an inch from one end of the tumor, and transversely to the axis of the same. It is then carried through, until a double tail, at least six inches in length, is left hanging from the point at which it entered; it is next carried across the base of the tumor, entering and passing out beyond its lateral limits, so as to leave a series of double loops about nine inches in length on each side (fig. 195). Every one of these loops should be made about three-quarters of an inch apart, including that space of the tumor, and the last loop should be brought out through a fold of healthy integument beyond the tumor. In this way we have a series of double loops, one white, and the other black, on each side (fig. 195). All the white loops should now be cut on one side, and the black loops on the other, leaving hanging ends of thread of corresponding colors. The tumor may now be strangulated by drawing down and knotting firmly each pair of white threads on one side and each pair of black ones on the other. In this way the tumor is divided into segments, each of which is strangulated, by a nose and a knot: by black nooses and white knots on one side, by white nooses and black knots on the other (fig. 196). The cicatrix resulting from the removal of a nevus is usually firm and healthy, but in some instances I have seen it degenerate into a hard warty mass requiring subsequent excision. The ligature may be used successfully at all ages. I have repeatedly tied large nevi in infants a month or two old, without meeting with any accident. It has been proposed by Mr. Curling to ligature the nevus subcutaneously, by passing a thread around its base, under the skin, and then tightening it. This may succeed when the growth is of small size, and is useful when so situated that a cicatrix is objectionable. Mr. Startin has very ingeniously proposed a plan, which I have advantageously adopted in some cases, of elastic subcutaneous strangulation, by fixing a vulcanized india-rubber ring, put upon the stretch, on to the noose of the ligature, and then keeping up steady traction upon it. The annexed cut (fig. 197) represents a nevus with two ligatures (a, a) passed subcutaneously round it, in opposite directions, and attached to india-rubber rings (b, b), to which tapes are tied, by which the traction is made. Fig. 197. HEMORRHAGIC DIATHESIS. In connection with diseases of the arteries, it may be stated that, in some constitutions, it is found, though, fortunately, very rarely, that there is a great tendency to very troublesome, indeed almost uncontrollable, bleeding from trivial wounds; life being put in jeopardy, or even lost, by the hemorrhage resulting from the extraction of a tooth, the opening of an abscess, lancing the gums, or some equally slight, unimportant surgical nrocedure. The blood in 570 DISEASES OF THE NERVOUS SYSTEM. these cases does not flow in a jet, but continues to trickle in an oozing stream, apparently from the capillaries rather than the arteries of the part. This dis- position is usually congenital, and in most cases hereditary; in other instances it appeared to result from the acquirement of some peculiar cachectic or scor- butic condition. The precise condition on which this hemorrhagic tendency is dependent has not been very clearly made out. When hereditary, it occurs in individuals who are robust, strong, and otherwise healthy. When acquired, it is usually met with in individuals who have been depressed in power by over- work, bad and insufficient food, or venereal excesses; and is evidently owing to defective nutrition. In all cases, the blood is thin and watery, apparently defi- cient in fibrine, and the capillaries easily lacerable and not sufficiently contrac- tile. In such cases as these, care must be taken not to make any surgical wounds if they can possibly be avoided; though it is a remarkable fact, that this condition seems only to have been met with after trivial injuries of the kind above mentioned, and not to have been encountered in any really serious surgical case. In the treatment of the diathesis little can be done. It has been proposed to administer saline hydragogue purgatives, with a view of inspissating the blood. I should, however, imagine that an improvement of the general health, by careful attention to food, exercise, etc. would be the best means of increasing the plasticity of this fluid. In the event of actual bleed- ing occurring in such cases as these, the employment of pressure, or the appli- cation of the actual or electric cautery, will constitute the best means of arrest- ing the hemorrhage. In some cases the electric cautery may be advantageously substituted for the knife, when it is desirable to remove parts in persons suffer- ing from this diathesis. By this means, the smaller amputations even may be performed, as has been successfully done by Mr. Marshall. CHAPTER XL. DISEASES OF THE NERVOUS SYSTEM. Inflammation of the nerves, or neuritis, is not of very unfrequent occurrence, being usually the result of rheumatic inflammation, of wounds, or strains. When rheumatic, it principally affects the nerves of the face and of the lower extremity. The symptoms consist of tenderness on pressure along the course of the nerve, with severe continuous pains, ramifying down its trunk and branches, with occasional violent exacerbations, especially on moving or touch- ing the part, and at night; there is usually swelling along the course of the trunk, and some constitutional pyrexia. When chronic, this condition may readily be confounded with neuralgia, of which, indeed, it constitutes one variety. On examination after death, in these cases, the sheath of the nerve will be found injected and swollen, and the nervous tissue softened. The treat- ment consists in the employment of antiphlogistic means; cupping or the application of leeches, according to situation, poppy or belladonna fomentations, and local emollients. When rheumatic, the acetous extract of colctncum is the best remedy that can be administered; when of a more chronic and nocturnal character, the iodide of potass, either alone or in combination with sarsaparilla, may advantageously be given. NEURALGIA. 571 NEURALGIA. In this disease, pain in the course of a nerve or greatly increased superficial sensibility, is the characteristic symptom. It is of all degrees of severity, some- times moderate, at others unendurable, even by those who possess the greatest fortitude; when severe, it usually comes on suddenly, with a kind of shock, and continues of a sharp darting or tearing character, coursing along the trunk or ramifications of the affected nerve, the distribution of which may often be distinctly indicated by the direction the pain takes. It is often accompanied by other sensations, such as a tickling, smarting, or creeping feeling on the affected surface; in some instances relieved by pressure, in others increased by the slightest touch, or movement of the part. Occasionally there is spasm in the muscles supplied by the affected nerve ; in others, heat and redness of the sur- face, with increased secretion from the neighboring organs, as a flow of saliva or tears, when the nerves of the eye or jaw are implicated. The duration of an attack may vary from a few moments to many days or months, the pain being most commonly intermittent or remittent, often irregularly so, but in some instances the periodicity is well marked. This disease may affect almost any part of the body; it is most commonly seated distinctly in the trunk and branches of a nerve. The divisions of the fifth pair are especially liable to be affected; it may extend to the whole of the branches of this nerve on one side of the head and face, or more commonly it is confined to one of its principal divisions, such as the infra-orbital, which is espe- cially liable to be affected by it; in many instances it is seated in the temporal and dental. Not unfrequently some of the terminal twigs merely, of one of these nerves, become the seat of intense pain; thus, occasionally, the affection is found limited to a patch on the cheek, brow, or temple; from which it scarcely ever shifts. The posterior branches of the dorsal spinal nerves, and the inter- costals, are also very commonly affected, though not to the same extent as the fifth pair. In other cases the whole of an organ, or part, becomes the seat of neuralgia, though no one nerve may appear to be distinctly implicated; thus, the testes, the breast, the uterine organs, or one of the larger joints, as the hip or knee, is occasionally the seat of severe suffering of this kind. An extreme degree of cutaneous sensibility is a marked feature in the affection, in some cases the patient wincing and suffering severely whenever the skin is pinched or touched, however lightly. The causes of this very painful disease, are very various; in many instances they appear to be purely of a nervous character; depressing influences of all kinds being especially likely to produce it; thus, debilitating diseases, mental depression, and particularly exposure to malaria, are common occasioning causes; those forms of the disease that arise from malarial influences, or from exposure to simple cold and wet, usually assume a very intermitting or periodical charac- ter, and are commonly seated in the nerves of the head. The hysterical tem- perament very frequently disposes to the spinal and articular forms of neuralgia. Various sources of peripheral irritation, as loaded bowels, the irritation of worms, and carious teeth, may be recognized as producing some of the more obscure varieties of the disease. Neuralgia may also arise from any compression exercised upon the trunk of a nerve, and thus indeed some of the more intractable forms of the affection have their origin. Thus, the pressure of a tumor of any kind, or of a piece of dead bone, may give rise to the most intense pain in the part supplied by the irritated nerve; and it is not improbable that in many of the cases of neuralgia in the branches of the fifth, pain may be owing to periosteal inflammation, or other disease of the osseous canals, through which these nerves pass. The diagnosis of neuralgia, though usually effected without any difficulty, is in some cases a little embarrassing, as the pain may occasionally simulate that 572 DISEASES OF THE NERVOUS SYSTEM. of organic disease or inflammation of a part. From organic disease of the part that is the seat of suffering, such as the hip, the knee, the testis, or the breast, this disease may usually be distinguished by the co-existence of cutaneous sen- sibility, the existence of the hysterical temperament, and the absence of the other signs that would accompany lesion of structure in the part affected. From inflammation the diagnosis is usually sufficiently easy by attending to the intermittent character of the neuralgic pain, its occurrence in hysterical tempera- ments, and in the absence of the constitutional symptoms of inflammation. But occasionally when local inflammatory irritation is conjoined with the neu- ralgia, the diagnosis is truly difficult. Here the presence of cutaneous sensibility and the relief of the pain by firm pressure will indicate neuralgia; whereas, in inflammation there is no tenderness of surface, but the suffering is aggravated by deep pressure. The treatment of neuralgia must have reference to the cause of the disease, and will be successful or not according as this may be more or less readily removed. So long as the conditions that primarily occasion the disease subsist, the pain is likely to continue ; and if these conditions are irremovable the dis- ease may be looked upon as necessarily incurable, though the suffering may be alleviated by appropriate means. When arising from any central nervous affec- tion, there may be the fear of the ultimate occurrence of disease of a more serious type, such as epilepsy, insanity, &c. When occurring in the hysterical temperament, the administration of the more stimulating and stronger preparations of iron, such as the sulphate, the sesquichloride, or the mistura ferri comp., either alone or in combination with quinine, with attention to the state of the bowels and of the uterine functions, and a general tonic regimen calculated to brace and improve the general health, such as sea-bathing, the cold douche, or sponging will be found to be of essen- tial service. In some of these cases the combination of zinc, especially the vale- rianate with the fetid gums, will remove the disease when iron does not influence it much. At the same time the application or inunction of belladonna or aconite plasters and liniments may be of service. When the neuralgia is distinctly periodical, quinine in full doses, or the liquor arsenicalis, will usually effect a speedy cure. When rheumatic, occurring in debilitated subjects, and attended by distinct nocturnal exacerbations of pain, no remedy exercises so great an impression upon it as the iodide of potass, especially when administed in com- bination with quinine. In the more severe and protracted forms of the disease, relief may be occa- sionally obtained by attention to the state of the liver and digestive organs, by a course of some of the more purgative mineral waters, and by the occasional exhibition of aloeties or croton oil, followed by the administration of tonic reme- dies. In many cases, all these means, however, are unfortunately unavailing, and the sufferer is doomed to an existence of constant pain, except when the disease appears to cease of itself, or has its intensity blunted by the administra- tion of the more powerful sedatives, such as morphia internally, or aconite or atropine externally. In these distressing cases, the sufferer is ready to grasp at any means of relief that is held out to him, and section of the affected nerve is not unfrequently recommended as a last chance of the removal of the disease. It is clear, however, that such an operation, though occasionally productive of temporary relief, cannot in many cases be expected to benefit the patient mate- rially; for by it the cause of the neuralgia is not removed, and it can conse- quently only be of service when the pain is peripheral, occasioned by some local irritation existing between the part cut and the terminal branches of the nerve. If dependent on any central cause, or on local irritation existing higher up than the point divided, it must eventually be useless. Thus, if the source of irrita- tion exist in the dental branches of the infra-orbital, the division of this trunk might be useful; but if the pain be occasioned by any pressure to which this ■ NEUROMA. 573 nerve may be subjected in its passage through its canal by a carious state of the bones, or by disease of the periosteum, it would be unavailing; though it is a remarkable fact that it not unfrequently happens after these operations that there is a temporary cessation in the pain for a few weeks or months. In some of these cases, however, the pain shifts its seat from the branch operated on to another division of the same trunk; thus, if the infra-orbital be divided, the submental becomes the seat of pain. Or this may ascend, as it were, to the point at which the nerve was divided; as, in amputation for neuralgia of the knee, the pain may return to the stump, and again when this is removed a second or even third time. The nerves on which this operation has been most frequently performed are the infra-orbital and the submental. Should it ever be thought necessary to do it, it would be proper not only to divide the nerve but to excise a portion of it, otherwise reunion will speedily take place, and the continuity of the nerve being re-established the operation will fail. The procedure simply consists in cutting down on the trunk where it escapes from the foramen, isolating and dissecting out a portion of it; in doing this, no great difficulty can be experienced by any one possessing moderate anatomical knowledge. [In a recently published paper Dr. Carnochan, of New York, strongly advo- cates the performance of a novel operation for the cure of aggravated cases of tic-douloureux of the face, or neuralgia of the second branch of the fifth pair of nerves. He believes that in such cases the " key of the operation is the removal of the ganglion of Meckel, or its insulation from the encephalon." In the operations which he reports, Dr. Carnochan, after making free incisions on the face, perforated both the anterior and posterior walls of the antrum, and removed the ganglion of Meckel from its position in the spheno-maxillary fossa. He at the same time exsected a portion of the superior maxillary nerve an inch and three quarters, or two inches in length, dividing the trunk of the nerve across, immediately below the foramen rotundum. The examination of the portion of nerve removed, in every instance revealed similar appearances. The trunk was thickened, vascular, and enlarged; the neurilemma and nerve proper being alike affected. The result of the three ope- rations reported was satisfactory in the highest degree; no unfavorable conse- quences followed, and the patients were completely relieved of their agonizing complaint. An operation somewhat similar to the above has been repeatedly and success- fully performed by American surgeons for the excision of the inferior dental branch of the lower maxillary nerve. To effect this an incision should be made over the perpendicular ramus of the lower jaw, and the masseter muscle divided in the direction of its fibres down to the bone. The crown of a trephine should then be applied upon the bone at a point immediately below the entrance of the nerve into the dental canal. The trunk of the nerve to the extent of half an inch or more in length may thus be easily exposed and removed. The relief afforded to the patient has, as far as we are aware, in every case been prompt and enduring.] NEUROMA. By neuroma is meant a tumor connected with a nerve. These growths have been well described by Mr. R. W. Smith, in a recent Monograph on the subject, in which, indeed, the principal part of our knowledge of this subject is contained. These tumors vary in size from a millet-seed to that of a melon, are usually solid, and composed of fibrous tissue, but when they attain a large bulk, cavities may form in them, containing a yellowish or brownish serous-looking fluid, apparently owing to the disintegration of the central portions of the mass. In shape they are 574 DISEASES OF THE NERVOUS "SYSTEM. usually oval or oblong, their long axis corresponding to the course of the nerve (fig. 198); they grow slowly, and are movable trans- Fig. 198. versely, but not in the direction of the nervous trunk on which they are seated; they have no appearance of ma- lignancy, and however large they become never contract adhesions to the integument nor involve its structure. These tumors commonly only affect the nerves of the spinal system, but Berard has met with one case of the disease on a ganglionic nerve. Most commonly the tumors are single, and then are usually attended with very severe lancinating or neuralgic pain, which extends, however, only to the parts below the tumor, and is commonly of a paroxysmal character. This pain is evidently owing to the stretching of the nervous twigs as they pass along the convexity of the growth. When single and painful, these tumors commonly go by the name of the painful subcutaneous tubercle, and are then usually met with from the size of a pin's head to that of a cherry-stone, commonly seated upon the limbs, and most frequently in connection with the nerves of the lower extremity; but they may be situated upon the arm, the trunk, or even on the scrotum and cheek, where, however, they are not so commonly met with. Wherever they occur they are acutely and intolerably painful on being touched, and are usually tender as well. In structure, the painful subcutaneous tubercle resembles exactly the ordinary neuromatous tumor, being composed of a white or greyish fibrous mass developed in the neurilemma, and having nervous filaments stretched through or over it- The nervous trunk above and below the tumor is normal; it is only where it comes in contact with it, and is exposed to its pressure, that it undergoes the change indicated. It is a very remarkable fact, that though neuromatous tumors when single, or when but two or three exist, are most acutely painful, yet, that when they are generally diffused over the body they lose their sensibility and are unattended by any inconvenience, except such as arises from their numbers and bulk. The number of these masses thus formed is often amazingly great; # thus, in one of Mr. Smith's cases, he counted in the two lower extremities alone more than 250 of these tumors, besides those in other parts of the body. In another case related by Mr. Smith, there were upwards of 200 small neuromata scattered over the sides of the chest and abdomen, 450 on the right lower ex- tremity, and upwards of 300 on the left, altogether probably not less than 2000 of these growths in "this unprecedented case." Traumatic neuromata may arise from the wound, or partial division of nerves, and occasion the most intense agony. Sometimes growths of this description of a fusiform shape, and varying from a cherry-stone to a pigeon's egg in size, are met with in stumps after amputations; in many instances unattended by inconvenience, but occasionally giving rise to a very severe degree of pain. The treatment of painful neuromata whether of an idiopathic, or traumatic character, or existing in stumps, consists in their excision. After removal, the part supplied by the nerve, which is usually necessarily divided, becomes paralyzed for a time, but may eventually regain its sensibility. In some cases, however, by cautious dissection, the tumor may be removed from the nerve that is in contact with it, without cutting this across. This has been done by Velpeau in the case of a neuroma of the sciatic nerve. When these tumors are numerous, they should not be interfered with, and if unattended by pain, they need not be excised unless their bulk prove inconvenient. TETANUS. 575 TETANUS. Tetanus is a disease consisting essentially in an excited state of the spinal cord and the medulla oblongata, in fact of the whole true spinal system, giving rise to painful and continued spasms of the voluntary muscles and the diaphragm, alternating with incomplete relaxation and usually terminating fatally. This, which is one of the most serious and distressing diseases to which the nervous system is liable, is, in the great majority of instances, of a traumatic nature, being the consequence of some wound that implicates or irritates a portion of the peripheral nervous system; the local irritation so produced, being propagated to, and exciting the nervous centres, the excitation of which becomes persistent, and continues after the local cause has been removed, inducing reflex muscular movements in various parts of the body. The irritation of the nervous system, however, that induces tetanus, may arise from other sources besides surgical wounds, occasioning the idiopathic form of the disease; thus, for instance, the presence of worms in the intestinal canal, exposure to cold and wet, and even the uterine irritation following abortion, have been known to occasion it. These causes, however, rarely give rise to it in this country, and we must consequently regard it as a disease chiefly arising from traumatic lesion of some kind. Tetanus may be occasioned by injuries that do not give rise to breach of surface; thus I have known it occur in a child who was suddenly thrown down upon its back by another at play; and Dr. Reid mentions a case produced by the stroke of a whip. But certainly in the great majority of cases, it is directly occasioned by a wound of some kind; and then it will generally be found that a nervous twig has been lacerated, divided, or inflamed, thus in a case of tetanus following a wound of the knee, in a patient, who died in University College Hospital, a small branch of the internal cutaneous nerve was found to have been injured and was inflamed; and, in another patient who died of tetanus about sixteen days after treading on a rusty nail, a black speck was found in the internal plantar nerve, where it had been wounded by the nail. In another case under my care, in which tetanus resulted from a bruise of the back, and terminated in death, the injured nerve (a dorsal branch) was found lying bare and reddened in the wound, and on tracing it up to the spinal cord, its sheath was found to be much injured, ecchymosed, and with a large vessel running down it. The kind of wound, as well as its situation, doubtless influences materially the occurrence of the disease. Though it certainly more frequently follows punctured, torn, and lacerated, than clean-cut wounds, yet it occasionally complicates these, even when the result of surgical operations; thus, it has been known to follow the removal of the breast, amputations, the ligature of the larger arteries, and the operation for hernia. It is the common belief, both in the profession and out of it, that wounds of the hands and feet, and more especially of the ball of the thumb and of the great toe, are more likely to be followed by tetanus than those in other situations. I think the truth of this opinion may be doubted; though it is not improbable that tetanus may occur more frequently after injuries of these regions, simply because punctured and lacerated wounds are more common here than elsewhere. It cannot well be supposed to be owing to the tendons and fascia that abound here, as it is seldom, if ever, met with after operations for tenotomy, which are so commonly prac- tised on the feet. Tetanus is especially apt to occur in feeble and debilitated individuals, and, indeed, may be looked upon as a disease of debility; hence any condition that lowers the tone of the nervous system is especially likely to occasion it. Thus, in unhealthy tropical climates, as in some of the West India Islands, and amongst the marshes of Cayenne, it is said to occur with peculiar frequency, the most trifling scratches or punctures being followed by the disease. The 576 DISEASES OF THE NERVOUS SYSTEM. exposure also of the wounded on the field of battle to cold, wet, and night air, is especially liable to occasion it. Thus, after the battle of Bautzen, where the wounded were left on the field during the night, exposed to severe cold, Larrey found on the following morning that more than one hundred were affected by tetanus. It may occur at all ages, but I believe is most frequently met with at the early and advanced periods of life. I have at least most commonly seen it either in very young or in old people; most frequently, certainly, in the young. In this country it rarely opcurs amongst infants, but in hot climates it is said not unfrequently to be met with shortly after birth, from the irritation occa- sioned by the ligature of the umbilical cord. Tetanus at times appears to occur epidemically. No case may occur in a hospital for a year or two, and then several will happen at or about the same time. This I have often observed. Tetanus may take place at any period after the infliction of the wound that occasions it. In hot climates especially it may occur very speedily; thus, Dr. Robinson relates the case of a negro servant in the West Indies, who scratched his finger with a broken plate, and died of tetanus in a quarter of an hour. It is very seldom, however, in temperate climates, that it supervenes before the fourth or fifth day. Larrey, who had great experience of this dis- ease during Napoleon's campaigns in Egypt, met with it most frequently be- tween the fifth and fifteenth days after the infliction of the wound. According to the experience of the surgeons of the Peninsular War, under whose obser- vation many hundred cases came, the disease does not show itself after the twenty-second day; but though this may be the general rule, Sir G. Blane has related a case in which it took place as late as a month after the infliction of the wound. It is stated that it may occur after the cicatrization of a wound is completed; when this happens the disease must rather be looked upon as being of an idiopathic character, accidentally occurring in a person who has been recently injured. r Tetanus may be acute or chronic, being in some instances fatal in the course of a few hours, but usually lasting for several days. If the patient survive this time, the disease will commonly run on to the eighth or tenth day, and occasionally even for a longer period than this ; thus, S. Cooper mentions a case in which it continued in a soldier for five weeks after amputation. As a general rule, the more acute the case, the more dangerous is the disease. In chronic cases there is good hope of the patient's recovery. Symptoms. — The invasion of the disease is often preceded by a general uneasiness on the part of the patient, a sensation of fear, or a sense of impending mischief. Abernethy was of opinion that tetanus was usually ushered in by a disturbed state of the digestive organs, the stools being offen- sive, and indicative of much gastric irritation. When the disease sets in gra- dually, it may be somewhat difficult of recognition in its early stages; if it comes on suddenly, its nature is immediately evident. It is a remarkable fact that the cramps do not begin in the parts injured; but, wherever this may be situated, they are always first noticed in the muscles supplied by the portio dura of the seventh; and throughout, it is principally these and the muscles of respiration that are affected. The first symptoms usually consist in the patient being unable to open his mouth widely, to take food or drink, the muscles about the temples, jaw, and neck, feeling stiff and rigid; this con- dition has given to the disease the popular term of lock-jaw. As the affection advances, the countenance assumes a peculiar expression of pain and anguish, the features are fixed or convulsed from time to time, and the angles of the mouth drawn up, constituting the appearance called the "risus sardonicus." When fairly set in, the disease is marked by spasms of the voluntary muscles of the most violent character, with much pain and partial remissions. The pain is of that kind that attends ordinary cramp in the muscles, as of the legs, and TREATMENT OF TETANUS. 577 is usually very severe. The spasms are often of a jerking character, the patient being suddenly thrown up, or twisted on one side; the breath being drawn with a loud sobbing catch from spasm of the diaphragm, and from the same cause there is usually violent pain experienced in the epigastric region, darting across to the spine. The muscles of the trunk are usually affected next in order of frequency to those of the head and neck, the body being bent back- wards so as to form a complete arch; more rarely it is drawn forwards, and still less frequently to one side. In some cases the body becomes perfectly rigid, like a piece of wood, the belly being drawn in, and the chest expanded. It is said that in severe cases the spasms have been of so violent a character, the muscles have been ruptured, teeth broken, and the tongue lacerated. In the numerous cases of tetanus that I have unfortunately witnessed, it has never fallen to my lot to see any effects of this kind produced, the spasms, indeed, not in general being of a very violent, though of a continuous, and very painful character. The intellectual faculties are not disturbed in these cases, and the mind continues clear to the last. In most instances there is a good deal of heat of surface, and quickness of pulse, not from any febrile disturbance, for this disease is unattended by symptoms of pyrexia, but apparently simply from the violence of the muscular contractions. The prolongation of life appears to depend greatly upon the intensity of the convulsive movements: the more severe these are, the sooner does death result. The fatal termination occurs not so much from any great physical lesion, or disturbance of important parts, as from exhaustion, consequent on the frequency of the tetanic spasms. The morbid appearances found after death throw little light on the nature of this affection. Indeed, the only morbid condition that is constantly found, is a degree of inflammation of a nervous twig leading from and implicated in the wound, that has occasioned the disease. This morbid state I have never found wanting. In all cases of fatal tetanus that I have seen in which a careful dissection has been made, these signs of inflammation of a nerve communicating with the wound have been found, and the vascularity, which is often very intense, may be traced up the neurilemma often to a considerable distance; besides this, there is usually a degree of congestion of the brain and spinal cord, with some bloody fluid in the ventricles and in the subarachnoid space. Nothing in any way of a special character has been revealed by these investigations, which, as yet, have not elucidated the true nature of tetanus, any more than that of many other nervous diseases, such as hysteria and chorea. The treatment of tetanus is of a local and of a constitutional character. The local treatment has for its object the removal of the irritation that has induced the tetanic condition. It is true that when once tetanic excitement has been set up in the cord it has a tendency to continue, and cannot be removed by the mere abstraction or cessation of the local irritation that gave rise to it in the first instance. It is, however, only reasonable to suppose that other treatment will succeed best if local irritation be removed, and, indeed, so long as this continues to keep up the centric nervous disturbance, no general means can be expected to succeed; as they will have not only to combat already existing disease, but also to overcome the continuous excitement maintained by the local disturbance. Hence, it is of use to get the wound into as healthy a state as possible, and to see that it is clean, free from foreign bodies, and not inflamed. In order effectually to remove all local disturbance, amputation has been had recourse to, but though this may have succeeded in checking some of the more chronic forms of the disease, yet other and milder local means have sufficed equally well, and in the majority of cases it has had no effect, and hence so severe an operation can scarcely be recommended for adoption. The division of the injured nerve, if there be one that has been punctured or lacerated, has occasionally proved successful. Thus, in a case of tetanus following injury of 37 578 DISEASES OF THE NERVOUS SYSTEM. the supra-orbital nerve, Larrey cut this across, and the patient was cured. In a midshipman, in whom tetanus came on the day after the sole of the foot had been wounded by treading on a rusty nail, Murray divided the posterior tibial nerve, and thus cured the patient. In those cases in which no special nerve appears to have been injured, Listen's recommendation of making a /\ shaped incision down to the bone, and above the part, so as to insulate it completely, may be advantageously followed. After the nerve has been divided, or the part properly insulated, some solution of atropine may be applied to it, so as still further to lessen local irritation. In the constitutional treatment of the disease, it is necessary to bear in mind that tetanus is an affection of debility, the violence of the spasmodic paroxysms giving an appearance of false strength to the patient, and that the principal source of danger and death is from fatigue induced by the energy of the mus- cular movements and the consequent want of rest. The means adopted should, therefore, have for their object the removal of irritation and the support of the patient's strength, to enable him to hold up against the disease. The first thing to be done is to clear the bowels well out with a dose of calomel and scammony, or a drop of croton oil, aided, if necessary, by turpentine enemata. The patient should then be kept perfectly quiet in a room by him- self, a screen, or muslin curtains, as recommended by Dr. Marshall Hall, being drawn round the bed: noise or movement of any kind increasing the spasms greatly. With the view of allaying the spinal irritation, the most effectual means consist perhaps in the plan recommended by Dr. Todd, of applying an ox's gut or gullet filled with ice along the whole length of the spine. This is a powerful depressing agent, and, unless care be taken, may lower the heart's action too much, or indeed completely extinguish it. It may, however, be applied with safety for six, eight, or ten hours, the condition of the patient being looked to in the meanwhile. Sedative or antispasmodic agents are seldom of much service. I have seen many drugs of this kind employed, without producing any material effect in lessening the violence of the convulsions. In some cases, however, the inhalation of ether and chloroform materially lessens their severity and gives the patient temporary ease; and there are instances on record from which it would appear that these agents have occasionally effected a cure. Mr. Miller speaks highly of the cannabis indica pushed to narcotism, 3 grains of the extract, or 30 minims of the tincture being given every half hour or hour. In one case, at Dr. Garrod's suggestion, I tried atropine cnder- mically on a blistered surface, and gave conium internally in large doses, and although the patient, an old man, eventually died exhausted, yet these agents appeared to exercise a marked influence in diminishing the violence of the spasms, and I should be induced to attach much importance to their adminis- tration. Dr. Elliotson has spoken highly of the preparations of iron, especially of the carbonate, in these cases. At the same time that measures such as these are had recourse to, it must not be forgotten that the disease is one of great exhaustion, and that the patient will die worn out, unless he be supplied with plenty of nourishment. Beef-tea and wine should, therefore, be administered by the mouth, and nutritious enemata by the rectum, and in this way the powers of life may be supported until the violence of the disease expends itself. In the more acute forms of tetanus all remedies appear to fail, the patient speedily being destroyed by the disease. In the subacute or chronic varieties recovery may take place, and it is in these cases that sedatives, such as conium and cannabis indica, have been of use. I am, however, disposed to think that in these chronic cases much may be done by simple, and little by specific treatment — clearing out the bowels by turpentine enemata, the internal admin- istration of calomel with some sedative, and keeping up the powers of the system till the disease wears itself out. PERIOSTITIS. — OSTEITIS. 579 DISEASES OF THE ORGANS OF LOCOMOTION. CHAPTER XLI. DISEASES OF BONES. PERIOSTITIS. Inflammation of the periosteum is of common occurrence, as the result of injuries, as a consequence of syphilis and rheumatism, or as a natural process dependent on disease of the subjacent bone. It often affects the membrane covering the shaft of a bone, and very commonly attacks the articular end, becoming associated with inflammation of the contiguous joint. When acute, the membrane becomes thickened, soft, and vascular, and loosens from the sub- jacent bone. When chronically inflamed, the periosteum becomes thickened by the deposit of plastic matter within and beneath it, and the subjacent bone usually participates in the changes, undergoing hypertrophy and induration. In some cases, but rarely, suppuration and death of the layer of bone imme- diately subjacent to the affected membrane take place. The symptoms of periostitis consist of a hard but somewhat puffy swelling, not distinctly circumscribed, and attended by much pain in the part, especially at night, with tenderness on pressure. In the treatment of the acute form of the affection, the free application of leeches, with hot fomentations, and the exhibition of calomel and opium, will arrest the disease, and give relief to the patient. In the more chronic form, the continued administration of the iodide of potass will take down the swelling, remove the nocturnal pains, and materially improve the local condition of the part. Added to this, the occasional application of leeches and repeated blister- ing will be of essential service. If there is much thickening, considerable relief will be afforded by the free division of the periosteum down to the bone, either through the skin or by means of a tenotome slid under it. osteitis. Inflammation of bone may arise from the same constitutional causes as the preceding disease, but most commonly occurs as the result of injury, either accidental or inflicted by the surgeon in an operation. When a portion of bone is inflamed, the periosteum and medullary membrane participate in the morbid action, and, together with the affected osseous structure, becomes highly vascu- lar; at the same time the inflamed bone becomes expanded and softened, partly in consequence of changes induced in its organic constituents, and partly in consequence of the cancellated structure becoming more cellular from inter- stitial absorption ; the cells becoming filled with a sero-sanguineous fluid. The compact structure of inflamed bone undergoes a peculiar kind of laminated expansion, so that a section of it presents an appearance of concentric parallel layers. When the inflammation is chronic, the bone is likewise expanded, but instead of becoming looser in its texture and softened, as in the acute form of the disease, it becomes very dense, indurated, and compact; looking and cutting more like ivory than ordinary bone. Sometimes considerable elongation, with- out much or any thickening, will take place. I have seen as the result of chronic osteitis the tibia one and a half to two inches longer than its fellow. 580 diseases of bones. The symptoms of osteitis consist of enlargement of the affected bone, with deep-seated pain and great tenderness in the limb; the pain, as in periostitis is greatly increased at night, and, when the disease is chronic, is much influ- enced by the state of the weather. In the treatment of the acute cases, our principal reliance must be on local leeching, with calomel and opium; in the more chronic form of the affection, when the bone has become thickened and enlarged, nothing of a curative kind can be adopted, and the only remedy consists in the administration of iodide of potass for the relief of the pain, with perhaps the occasional application of leeches. After a time, when all morbid action ceases, the hypertrophied bone does not give rise to any very serious inconvenience, except such perhaps as may be occasioned by its bulk. Osteitis is principally of importance to the surgeon from its connection with other more serious diseases of bones, in which it not unfrequently terminates. These conditions are suppuration of the bone, its ulceration, caries, and suppuration of bone. Suppuration of bone may occur in two forms, the acute and the chronic. The acute form of suppuration (osteo-pyelitis) is invariably of a diffused character. It usually arises as the result of injury inflicted Fig. 199. on bones in operations, as for instance in amputations, or the excision of joints, but sometimes occurs in connection with compound fractures. In it, the medullary membrane is pri- marily affected, the inflammation rapidly extending through the whole of the medullary canal and adjoining cancellous structure, which speedily becomes filled with pus. Mr. Stanley observes that the medullary membrane in this disease becomes vascular like the conjunctiva in chemosis, and is often black and gangrenous (osteo-myelitis). This purulent infiltration of the interior of the bone is very apt to give rise to phlebitis and pyemia, and hence becomes a most formidable affection, the pus finding its way into the veins of the bone, and from thence into the general current of the circulation. Osteo- pyelitis, phlebitis, and pyemia constitute a pathological se- quence that is by no means an uncommon cause of death after operations implicating the medullary canal. When the diploe of the skull is affected, the sinuses and cerebral veins may be found after death highly inflamed and filled with pus. In a case in which I excised the elbow-joint, the patient died of pyemia, and after death the interior of the humerus was found to be inflamed and filled with pus, and the axillary vein in a state of suppuration (fig. 199). The invasion of this disease, after an operation, is indicated by great and deep-seated pain, with much swelling, tension, oedema, and gene- ral redness of the limb or stump. The wound becomes sloughy, all discharge from it ceasing, rigors occur, and the symptoms of pyemia speedily set in. The treatment must be directed to the constitutional condition induced by the affection. The more chronic form of suppuration of bone usually assumes a circum- scribed character, and leads to the formation of abscess. These abscesses are usually met with in the cancellated structure, and occur with especial frequency in the head and lower end of the tibia. In some instances they are tolerably rapid in their formation, but in the majority of cases are excessively chronic. When of a more acute character, they are probably the result of the softening of tubercle previously deposited in the bone; and forming in the cancellous suppuration of bone. 581 Abscess in the head of the Tibia. Fig. 201. structure, are very apt to undermine the contiguous cartilage of incrustation and eventually to burst into the neighboring joint (fig. 200). When of a more chronic character, they are usually of very small size, and are deeply seated in the substance of the head, or in the medullary canal of the bone; the osseous sub- stance covering them having long been the seat of chronic inflammation, becomes greatly thickened and indurated. Most commonly the quantity of pus con- tained in these abscesses is extremely small, and it is often mixed with cheesy or tuberculous matter, or contains portions of necrosed bone intermingled with it. In some cases, however, Mr. Stanley has observed that abscesses of bone are large, containing a con siderable quantity of fluid. The symptoms of chronic abscess of bone are usually of the following character. The patient, after the receipt of an injury, perhaps, has noticed that at one spot the affected bone has become swollen and pain- ful ; the skin covering it preserving its natural color in the majority of cases, but in some instances be- coming red, glazed, and cedematous; the pain, which is of a lancinating and aching character is usually remittent, often ceasing for days, weeks, or months, and then returning under the influence of very trivial causes, with its original severity. It is especially troublesome at night, and is always associated with a degree of tenderness of the part; and indeed, in the intervals of its accession, it will be found on careful examination that there is always one tender spot in the enlarged and indurated bone. The persistence of these signs will usually point to the existence of a small circumscribed abscess under the thickened wall of the bone. But it must be borne in mind that the same local symptoms may be induced by the presence of a small por- tion of dead bone confined within an impervious casing, or even that they may arise from the simple pressure of osseous struc- ture, thickened by chronic inflammation. For all practical pur- poses the diagnosis is of little consequence, as the treatment is the same, whether the pain and other symptoms arise from the confinement of a few drops of pus, the inclusion of necrosed bone, or the pressure of the hypertrophied osseous tissue. The proper treatment of circumscribed abscess of bone has been pointed out by Brodie. It consists in trephining the bone with an instrument having a small crown, so as to make an aperture for the exit of the pus, of this size (fig. 201, 1). So soon as a vent has been given to this, which is often cheesy, and occasionally very offensive in its character, the patient will experience great and permanent relief. In performing this operation, there are several points that deserve special attention. The bone must be exposed by a "J" or V shaped incision, made over the spot which has been found to be uniformly tender on pressure; and to this the trephine should be applied. The trephine should have a small and deep crown of this size and shape (fig. 201), and it is well always to be provided with two instruments of the same shape and size that will exactly fit the same hole, lest one become disabled by the density and hardness of the osseous case that has to be perforated, as I have seen happen. When the trephine has penetrated to a sufficient depth, the button of bone may be removed 582 DISEASES OF BONES. by means of an elevator; but care should be taken not to perforate the whole thickness of the bone. The diseased cavity will very commonly at once be opened in this way, a small quantity of pus escaping, which may, however, readily be overlooked, as it is carried away in streaks with the blood, which flows freely from the cut bone. Should no pus escape, perhaps a portion of dead bone, or some dark gritty masses of disorganized osseous tissue are exposed; if so, they must be removed with a gouge. But if neither of these conditions are found, the surgeon must not be disappointed, but pierce the neighboring osseous tissue in different directions by means of a perforator, when perhaps the abscess will be opened; should it not be so, the patient will still, in all probability, be materially benefitted by the removal of the circle of bone, and the consequent relief to the compression of the osseous tissue. After the operation, the cavity left must be dressed from the bottom with wet lint, and a poultice be afterwards applied; it will gradually fill up with fibrous tissue, leaving the limb unimpaired in utility and strength. CARIES. By caries some surgeons mean a kind of ulceration of bone; others, again, a species of disintegration of the osseous tissue; and Stanley includes under this term the various changes consequent on the chronic suppuration of the cancel- lous structure. But caries, I think, properly means a disease of the bone charac- terized by increased vascularity, softening, and ultimate disintegration of the osseous tissue. It appears to consist in a breaking down of the organized portion of the bone, in consequence of which the earthy matters become eliminated in a granular, molecular, and almost diffluent form in the pus formed by the inflam- mation of the surrounding more healthy structures. On examining a portion of carious bone, it will be found to be porous and fragile, of a grey, brown, or blackish color; in parts broken down in softened masses, and at others hollowed out into cells, which contain a reddish-brown and oily fluid. The process of wasting which goes on in the bone, appears to be partly the result of ulceration, and partly of disintegration of its tissue. In many cases, small masses of dead bone lie loose and detached in the carious cavity. Around this carious portion, the bone, as well as the medullary and periosteal membranes, is usually extremely vascular; and, in many cases, hard- ened compact masses of osseous tissue will be found deposited around, or even forming the exterior wall of the carious cavity. These changes are most com- monly met with in the cancellous structure, but the compact tissue may likewise be affected. As it so frequently occurs in the cancellated tissue, it is commonly met with in the heads of bones; and here the disease is extremely dangerous, being apt to undermine and destroy the contiguous articular cartilage, and thus implicate the joint. This caries of the articular ends of bones is consequently a most serious affection, and is a very frequent cause of incurable joint disease, such as suppuration and destruction of cartilage, followed perhaps by partial anchylosis. Any bone may be affected by caries, but it is perhaps more fre- quently met with in the short and cancellous bones. Caries occurring in strumous constitutions, and affecting the short bones, as those of the tarsus, or the cancellated heads of the long bones, as the tibia, usually, if not always, commences in the centre of the bone, which becomes congested, softened, and disintegrated, in many cases without any external cause, but apparently simply from the diminution of vitality in those parts of the osseous structure which are farthest from the periosteum, and which do not, like the deeper structures of a long bone, receive a supply of blood from an internal or medullary membrane. In these cases, the inflammation of the soft investing parts, and the destruction of the joint, which usually ensues, is consecutive to the disease in the bone. SYMPTOMS AND TREATMENT OF CARIES. 583 The symptoms indicative of the occurrence of caries are of a very equivocal character, and are not unfrequently, in the early stages, mistaken for those of ordinary phlegmonous abscess or rheumatism. They consist of pain in the bone, with a good deal of redness and swelling in the soft tissues covering it; abscess at last forms, often of considerable size, and on letting out the pus, the character of the disease will be recognized, as the bare and rough bone may be felt with a probe, which sinks into depressions upon its surface, which, though rough, yields readily to the pressure of the instrument. The cavity of the abscess gradually contracts, leaving fistulous openings, which discharge a fetid pus, usually dark and sanious, intermixed with granules of bone, and containing a superabundance of the phosphates. The fistulous openings are generally sur- rounded or concealed by high spongy granulations, and the neighboring skin is duskily inflamed. Caries usually occurs in constitutions that have been debili- tated by struma or syphilis, often without any other apparent cause. In syphi- litic constitutions it is apt, however, to affect the surface of the bone, disinte- grating and eroding this in a remarkable manner. This condition has been described by Stanley as true ulceration of bone, and he regards it as distinct from caries, and analogous to ulcers of the soft parts. Here the disease does not penetrate deeply, but leaves the surface rough and porous, with a good deal of inflammation in the soft parts around the affected bone. He states, that it only occurs in adults, and in males, and is very chronic in its character; it is met with primarily in the bones of the spine, but also occurs on the articular surfaces in advanced stages of joint-disease. The treatment of caries must be conducted in reference to the constitutional cause that occasions it, the removal of which is the first and most essential ele- ment in effecting a cure. If it arise from syphilis, this must be eradicated ; if from struma, the general health must be improved. By the removal of causes such as these, the disease will often cease spontaneously, and even undergo cure, more especially in young subjects. Hence, it is well not to be in too great a hurry to interfere, by operative means, in the caries of the small bones of chil- dren. I have often seen cases, especially of caries of the bones of the hands and feet, in which an operation for the removal of carious bone was apparently indispensable, get well spontaneously by change of air, and attention to the general health of the child; the disintegrated particles of the diseased bone being eliminated piecemeal. In the first stage of caries, which is inflammatory, measures should be taken by means of appropriate local and constitutional antiphlogistics to subdue the activity and limit the extension of the disease; and when this has fallen into a chronic stage, constitutional alteratives should be employed. Amongst these, cod-liver oil, the iodides, and change of air, more especially to the sea-side, when the patient is young, should hold the first place. When, however, the disease has fallen into a chronic condition, and nature seems unable to eliminate the carious bone, all reparative action having ceased, or being inefficient for the restoration of the integrity of the part, an operation becomes necessary. When the operative procedure has reference to the diseased part itself, it is impossible to be too careful in delaying it until the acute stage of the disease has passed, and the inflammation in the bone and surrounding tissues has subsided into a chronic state. Unless this be done, the excited action set up by the operation will infallibly give fresh impetus to the disease, which will make more rapid progress, and may perhaps terminate in diffuse suppuration of the bone. The operations practised upon carious bones are of three kinds; consisting either in simple removal of the diseased portion of bone; — in the excision of the carious articular end; — or, in the amputation of the whole of the bone affected. The removal of the carious portion of bone is best effected by means of the 584 DISEASES OF BONES. gouge. This instrument is especially useful in those cases in which short, thick bones, or the articular ends of the long bones, are affected, Fig. 202. without the neighboring joints being implicated. In applying the gouge, the diseased portion of bone should be exposed by a crucial incision; and if necessary, its cavity opened by a small trephine. The gouge, fixed in a short, round handle is then freely applied, and the diseased tissues scooped and cut out. In order to do this efficiently it is desirable to be furnished with instruments of different shapes and sizes, so that there may be no difficulty in hollowing or cutting away every portion of bone that is implicated. I have found the gouge-forceps (fig. 207), a very useful addition to the gouge in clearing away angular fragments and projections of bone, and thus removing the whole of the diseased structures. In some cases Mr. Mar- shall's osteotrite (fig. 202) will be found a very serviceable in- strument, clearing away the softened carious bone without risk to the surrounding healthy structures. In removing the carious bone with these instruments, the surgeon may be sometimes at a loss to know when he has cut away enough. In this he may generally be guided by the dif- ference of texture between the diseased and healthy bone; the former cutting soft and gritty, readily yielding before the in- strument, whilst the latter is hard and resistant; so that when all the disease is removed the walls of the cavity left will be felt to be compact and smooth. In some cases it is true that the healthy bone may have been softened by inflammation; should there be any doubt as to the condition of what has been gouged out, it may be solved by putting the detritus into water, when, if carious, it will either wash white or black: whereas, if healthy, but inflamed, it will preserve its red tint. In operating on young children espe- cially, it is well not to have the gouges too sharp, lest the inflamed, but other- wise healthy, though somewhat softened bone be cut away together with the disintegrated caries. The cavity that is left should be lightly dressed from the bottom, and allowed to heal by granulation, when it will gradually fill up by fibrous material deposited in it. When the caries affects the articular ends of the bones, as those that enter into the formation of the elbow or shoulder-joints, it may be so situated as not to admit of removal in the way just indicated, but to require excision of the diseased articulation : these operations we shall consider in a subsequent chapter. When the caries involves a bone so extensively that neither of the preceding plans can successfully be put into operation, it becomes necessary to remove the disease either by the resection of the whole of the bone, if it be of small size, or by the amputation of the limb, if of greater magnitude, or if it affect the neighboring joints extensively. Thus, for instance, resection of the os calcis may be required for caries of that bone, whilst if the whole of the tarsus is affected, amputation is the only resource. In some cases of chronic disease of the tarsus, however, large portions of different bones may successfully be removed; and indeed I look upon these operations of gouging away and scraping out carious bones as preferable to the more formal operations of excision of special bones. In a case of very extended disease of the outer side of the ankle and foot, I removed three inches of the fibula, the greater part of the astragalus, the upper and outer part of the calca- neum, and the whole of the cuboid, leaving a large triangular cavity in the bones, which readily filled up, a most excellent limb resulting. NECROSIS. 585 NECROSIS. The transition from caries to necrosis is easy; caries may be regarded as the granular disintegration or molecular death of the osseous tissue, conjoined with suppuration of the surrounding healthy parts; whilst necrosis must be looked upon as the death of the osseous tissue as a whole, a condition indeed closely resembling that of gangrene of the soft parts. Whilst caries, however, chiefly affects the cancellous structures, necrosis is met with in the compact tissue of bone, and far more frequently occurs in the shafts than in the articular ends of the long bones. It is, however, occasionally found in the cancellous structure; thus in the head of the tibia, or in the os calcis, small masses of necrosed bone are not unfrequently found lying in the midst of carious or suppurating cavities. The different bones are affected by necrosis, with varying degrees of frequency. The tibia, at its anterior part is most frequently diseased; the femur in its lower third is also very commonly affected. The lower end of the humerus is not so often necrosed; but not uncommonly the phalanges of the fingers from whitlow, — the cranium from syphilis, — the lower jaw, from the emanations evolved in the manufacture of phosphorus matches, — and the clavicles and ulna, from injury or constitutional causes, are found affected by necrosis. The causes of necrosis are of very various character. We have just seen that it is predisposed to by the structure of particular parts of bone, and is more frequent in some bones than in others :—amongst the more constitutional causes, we may rank in the first line those cachectic conditions of the system that result from scrofula and syphilis, and those debilitated states of constitution that so frequently follow upon typhus fever: in these various states, the bone may sud- denly lose its vitality, more especially if the limb be subjected to slight accident, as concussion, or to exposure to some degree of cold. In some cases the disease results from the vitality of the bone being destroyed by the extension of inflam- mation to it from the neighboring tissues, as in some cases of whitlow, or by the bone becoming exposed by a neighboring abscess. Traumatic causes frequently give rise to necrosis. Thus the denudation of a bone by its periosteum being stripped off, may lead to its death; but though the bone thus injured often loses its vitality, yet, if the membrane be replaced, its life may be preserved; or even when exposed, adhesions may take place between it and the neighboring soft parts, or granulations be thrown out by its surface, which eventually form another periosteum. Necrosis frequently occurs as the result of the detachment and denudation of a portion, of bone in cases of bad compound fracture; so also the application of certain irritants, as the fumes of phosphorus, may occasion this disease, and hence it has occasionally been found that in lucifer-match manufactories, necrosis of the lower jaw is of fre- quent occurrence as a consequence of the acrid fumes that are eliminated getting access to the bone through carious teeth, or being applied to the exposed alveoli. In whatever way it originates, the necrosis may affect the outer laminae of the bone only, when it may be denominated peripheral; or the innermost layers that surround the medullary canal may perish, and then it may be termed cen- tral; or the whole thickness of a shaft, or of the substance of a short bone, may lose its vitality. The portion of bone that is necrosed, called the seques- trum, presents peculiar characters, by which its nature may at once be recog- nized. It is of a dirty yellowish-white color, and has a dull opaque look, and after exposure to the air, it gradually becomes of a deep brown or black tint; the margins are ragged, and more or less spiculated, and the free surface toler- ably smooth, but its attached surface is very irregular, rough, and uneven, pre- senting an eroded or worm-eaten appearance. When the sequestrum forms in the cancellous structure, it is usually of a blackish-grey color, irregular but 586 DISEASES OF BONES. somewhat ovoid in shape, as if the bony matter had been partially dissolved away, and here is frequently conjoined with caries of the surrounding bone. The symptoms of necrosis are divisible into two distinct periods. In the first the bone dies and undergoes separation, and an attempt is made by nature at the expulsion of that portion of it which has lost its vitality. In the second period the reparative processes for the restoration of the proper length and shape of the shaft are carried on: the particular character of the symptoms depends however not only on the stage, but also in a great measure on the seat and extent of the necrosis. In all cases it is ushered in by symptoms of local inflammation of a more or less intense and painful character; the skin becoming glazed, cedematous, and of a purplish-red tint; abscess, often of large size, and discharging great quantities of fetid or bloody pus, forms in the limb, and burrows widely, in proportion to the extent of the necrosis, amongst its cellular planes. If the suppuration be not so extensive as to jeopardize life, as occa- sionally happens when the thigh is the seat of disease, the patient sinking into rapid hectic, the suppurating cavity will gradually contract, leaving fistu- lous and sinuous tracts, often of great length and extent, leading to rough and bare bone, discharging a fetid and ichorous pus, and having their orifices sur- rounded by protuberant and glazed granulations. All these symptoms of inflam- mation, abscess, and wide-spread suppuration, have for their ultimate objects the separation and elimination of the dead bone, and the proper formation of new bone, as a substitute for that which has died. In the peripheral necrosis of the shafts of the long bones, as of the femur or tibia, the inflammatory symptoms just indicated are well marked, and the dis- ease usually runs a rapid course up to the period of the formation and discharge of the abscess. In the case of central necrosis, the pain is usually more severe than in the former case, and is peculiarly deep-seated and throbbing, being especially intense at night. The limb becomes very cedematous, red, and glazed; the bone enlarges greatly, and abscess at last forms, which spreads widely in the planes of cellular tissue, undermining the muscles, and producing general destruction of the limb, the tissues of which become rigid and condensed, having sinuses leading down through them. On introducing a probe into these channels, the instrument passes tbrough apertures in the bony case, termed cloaca (fig. 203), at the bottom of which the dead bone will be felt rough and bare. Though this is the general condition that occurs in central necrosis, it occasionally, but rarely happens, that a small portion of some of the internal lamellae of the bone dies, and being included in a greatly thickened case of new bone, gives rise to symptoms of osteitis, or closely resembling circumscribed abscess of bone, but not to those characterizing necrosis. When the whole thickness of a shaft dies, the symptoms are always of a very acute kind, the extent and gravity of the inflammatory and suppurative condi- tion being proportioned to that of the amount of bone that loses its vitality. It is a remarkable fact, however, that the articular ends usually escape, though these sometimes even become affected, and the joints involved. When the short cancellated bones or the articular ends of long bones, become the seat of necrosis, it commonly happens that the disease is far more chronic than in the cases described; abscess forming, which at first may not reveal its true nature, or being preceded by continual pain, may be looked upon as a disease of a rheumatic character. Suppuration at last occurs, sometimes rapidly opening into the neighboring joint, and disorganizing it with extreme constitutional disturbance, but more commonly it runs a very chronic course. On passing the probe down the fistulous openings that lead through the indurated and thickened 6oft parts, an aperture may usually be felt in the bone, at the bottom of which lies a necrosed mass not larger than a hazel-nut, surrounded by carious bone. Acute necrosis often attacks the long bones, especially the tibia and femur. PATHOLOGY OF NECROSIS. 587 In these cases violent and deep-seated pain occurs in the limb, which swells greatly Abscess soon forms along the whole line of bone; great constitutional disturbance ensues, and, unless the limb be amputated, death will usually speedily result. This form of necrosis chiefly occurs in young and cachectic subjects. On examination after removal, the bone will be found white, opaque, and dead-looking; the periosteum is detached, new bone is deposited, the sur- rounding parts infiltrated, and, usually, abscess around the bone to its whole length. In many cases the articular ends escape, the necrosis being confined to the shaft of the bone, which will be found to be detached from one or both epiphyses. To these the periosteum of the shaft, greatly thickened, will con- tinue to be adherent, and would have formed the organ for the reproduction of the bone, had the limb admitted of being saved. In extreme cases, the articu- lar ends even are involved, and the joints secondarily affected. The process of the separation of the dead bone, and of the formation of a new osseous tissue to supply the place of that which is necrosed, is one of the most interesting phenomena that the surgeon can study. The separation of the dead bone, or its exfoliation, is precisely similar to the mode in which a slough in soft parts separates, the time required being the only difference. Inflammatory action is set up so as to form a true line of demarcation and of separation in the substance of the bone that is still living, and that is immediately contiguous to that which has lost its vitality. In this way a groove is gradually deepened around the edge of the sequestrum, by the absorption, or rather disintegration of the earthy matter of the living bone, which is carried off by the pus formed in the course of this process; pus that, according to B. Cooper, contains 2£ per cent, of phosphate of lime. Along this gradually deepening line of separation, plastic matter is thrown out, from which granulations are formed which consti- tute a barrier as it were between the living and dead bone, and extending into the under surface of the sequestrum, become so implanted in the hollows and depressures which are there found, that this may continue to be firmly attached to the subjacent living bone after all osseous connection between them has ceased. This process of exfoliation may often be beautifully seen in the separation of the outer table of the skull in cases of necrosis of that bone. When occurring between the shaft and articular ends of a long bone, the process is precisely similar, though the line of separation is not quite so regular. When once the dead bone has been detached by the formation of this line of separation, nature adopts steps for its ultimate removal from the body, there being no evidence that it ever, under any circumstances, undergoes absorption. Miescher has shown that the detachment of small scales of bone may take place by the disintegration of their substance by a process of " insensible exfoliation," as he terms it. This process is a purely mechanical or physical one, and probably goes on in all dead bone that is in contact with pus, just as we see it take place in the ivory pegs used in the treatment of ununited fracture. It is this disintegration of the surface of the dead, together with the absorption of the margin of the living bone, in the formation of the line of separation, that explains the fact that the sequestrum will always be found to be of much smaller size than the cavity in which it is lodged. The ultimate expulsion of the loosened or exfoliated sequestrum is effected by the growth of the granulations below it pushing it off the surface, or out of the cavity in which it lies. When the necrosed bone is peripheral, it will be readily thrown off in this way, although it may for a time be fixed and entangled by the mere pressure and extension of the granulations. When the sequestrum is invaginated within old or new bone, the process of elimina- tion is necessarily very tardy, and may be difficult or impossible without sur- gical aid. The time required for the exfoliation and separation of dead bone varies greatly. When superficial and small in size, a few weeks may suffice; 588 DISEASES OF BONES, Fig. 203. but when affecting the long bones, or especially those of the ilium, the process may be extended over several years, and may terminate in the death of the patient from exhaustion before it is con- cluded ; the constitution being harassed and worn out by hectic induced by profuse suppuration. Or the disease may fall into a chronic state, the limb becoming rigid, with much condensation of tissues, with fistulous apertures lead- ing down to exposed but attached bone, and thus being a source of constant annoyance and suffering to the patient. The reparative process adopted by nature for the resto- ration of the integrity of the bone, a portion of which has necrosed, varies according to the extent of the loss of sub- stance. When the outer lamellae alone are necrosed, new bone is deposited by the surrounding periosteum, and the depression that has formed on the surface of the old bone is filled up by a kind o'f cicatricial fibrous tissue, which ulti- mately ossifies. If the whole of the inner lamellae of the shaft die, constituting central necrosis, the outer layers of bone become greatly consolidated and thickened by osseous matter deposited from the periosteum, in which, in the ma- jority of cases, the circular or oval apertures termed cloacx form for the ultimate extrusion of the sequestrum (fig. 203.) In some cases, however, no cloacae form, the dead bone continuing to be incased in the thickened outer layers. When the whole of a shaft dies, the reproduction takes place from various sources, principally from the periosteum, and perhaps the medullary membrane, if that is left, which become thickened, vascular, and detached from the necrosed bone. That the periosteum takes the principal share in the reproduction is evident from the fact that where it is deficient or has been destroyed, apertures (cloace) are left in the case of new bone. Then again the soft tissues of the limb generally, if thick, as in the thigh, contribute to the formation of plastic matter, which gradually ossifies, and so tends to strengthen the new case; and, lastly, the articular ends of the old bone still preserving their vitality, throw out sufficient osseous matter to consolidate themselves firmly to the new shaft that is formed. Thus it will be seen that the new bone is formed by the vascular and healthy tissues generally that sur- round the seat of disease, though in this reparative action the periosteum and medullary membrane take the chief share. In acute necrosis there is no time for reparative action to take place, but the periosteum will be found much thickened and vascular, separated from the dead bone, and occasionally lined with scales of new ossific matter, the first step towards the reproduction of a new shaft. The new bone which is deposited on those parts of the surface of the shaft from which scales of the old osseous tissue have been separated, or that enve- lopes the sequestrum when the whole thickness of the shaft necroses, is at first rough, porous, cancellated, and very vascular; after a time it gradually becomes more compact and harder, at the same time that it assimilates in bulk and shape to the bone, whose place it takes. When the new bone is deposited around the sequestra so as to envelope these in a kind of case, apertures of an oval or cir- cular form, cloacae, are formed in it; these serve for the escape of the discharges, and it is eventually through these that the dead bone is extended; they are said to correspond with points at which destruction of the periosteum has taken place. The case of new bone, which necessarily exceeds in circumference the old bone, as this is included within it, gradually contracts both in texture and in size, becoming firmer and smaller after the removal of the sequestrum; and OPERATIONS FOR NECROSIS. 589 the cloacae closing so soon as all dead bone has been extruded, it eventually acquires the proper size and shape of the bone; the medullary canal even be- coming lined by a proper membrane forming in it. The new bone usually forms with a rapidity that keeps pace with the death and separation of the old bone. In acute cases of necrosis in which amputa- tion has been performed but a few weeks after the setting in of the disease, a thick layer of new bone will sometimes be found under the periosteum; but in some instances, when the whole of a shaft is necrosed, the new case is not com- pleted, or has not become attached to the articular ends before these are sepa- rated from the shaft. In other cases again, though complete, it has not sufficient strength to resist the contractions of the muscles of the limb; under these circumstances, it may spontaneously fracture, as Fig. 204. happened in a case of necrosis of the thigh lately under my care in the hospital, or become shortened or bent. In other instances again, when the periosteum is deficient, new bone does not form (fig. 204); but as the sequestrum separates, the limb becomes shortened, loose, deformed, and useless. In the treatment of necrosis, the indications to be accom- plished are sufficiently simple, though the mode in which they have to be carried out often requires much patience and skill on the part of the surgeon. The first point to be attended to is to remove any constitu- tional or local cause that has occasioned or keeps up the dis- ease ; unless this be done, it is clear that the whole of the rest of the treatment must be ineffectual; thus, for instance, if the death of the bone appear to result from scrofula or spyhilis, those conditions must be corrected. So, again, if it arise in the lower jaw, from the fumes of phosphorus, the patient must necessarily be removed from their influence ; or, if it be threat- ened in consequence of denudation of bone, the best mode of prevention will be to lay down the flaps of integument, and so cover the exposed surface. After the cause has, in this way, been removed or counter- acted, the separation of the sequestrum should be left, as much as possible, to the unaided efforts of nature. The less the sur- geon interferes with this part of the process the better, for as has been justly observed by Wedemeyer, the boundaries of the necrosis are only known to nature, and the surgeon will most pro- bably either not reach, or pass altogether beyond them. Here much patience will be required for many weeks or months, and the utmost that the surgeon can do is to attend to the state of the patient's health, treating him carefully upon general principles, removing inflammatory mischief, by appropriate antiphlogistic means, opening abscesses as they form in the limb, and, at a later period, supporting the patient's strength by good diet, tonics, and general treatment, calculated to bear him up against the depressing and wasting influence of continued suppuration, and of the irri- tation induced by the disease. So soon as a sequestrum has been detached from the adjacent or underlying bone, by the proper extension of the granulating line of separation, the surgeon must proceed to its removal. In most cases it is sufficiently easy, when the necrosis is superficial, to ascertain that this separation has taken place, as the flat end of a probe may be pushed under the edge of the detached lamina. When, however, the sequestrum is deeply seated, it is not always so easy to ascertain that the separation has occurred, though, in the majority of cases, the introduction of a probe through one of the fistulous openings leading to the necrosed bone, and firm pressure exercised upon this, will enable the surgeon to 590 DISEASES OF BONES. I detect that degree of mobility which is characteristic of its being loose. In other cases, however, the sequestrum, though completely removed from all osse- ous connections, still continues to be fixed by the pressure of the surrounding granulations, and by the extension of its spiculae into the corresponding cavities of the new osseous case. This especially happens when the necrosis is central and invaginated, and the cloacae leading to it of such small size that but a limited portion of it is exposed. Here a more careful examination will be re- quired, and its looseness may sometimes be determined by pressing upon it with a probe in a kind of jerking manner, or by introducing two probes through different cloacae, at some distance from one another, and alternately bearing upon the exposed bone with one or other of them. Then, again, if the sound elicited by striking the end of the probe against the sequestrum, is a peculiarly hollow one, the detachment of the bone may be suspected. The duration of the disease, also, will probably throw some light upon the probable state of things inside the new case. The separation of the sequestrum having been ascertained, the surgeon must adopt measures for its extraction. If the necrosis is peripheral, all that is necessary is to make an incision down to it through the soft parts, and then to remove it with a pair of forceps, or to tilt it off the bed of granulations on which it is lying, by introducing the end of an elevator beneath its edge. When the necrosis is central, the sequestrum being imbedded in the new case, or covered in by old bone, the operative procedures for its removal are of a more complicated character. The difficulties here consist in the depth from the sur- face, and the obstacle offered by its passage through the soft parts in some cases, and in others, in the length and magnitude of the sequestrum in proportion to the small size of the cloacae, and the manner in which it lies, in a parallel direction to these openings. In cutting down upon the bone the surgeon must be guided by the direction and the course of the fistulous tracks that lead to the principal apertures in the new case, the incisions being carried in the axis of the limb, and carefully directed away from large blood-vessels and nerves. In many instances, however, the hemorrhage is somewhat abundant, in consequence of the injected state of the tissues furnishing a copious supply of blood, and their rigid condition preventing retraction of the vessels; this, however, may be arrested by the pressure of an assistant's fingers, and will soon gradually cease of itself. The bone having been freely exposed, it will sometimes be found that Fig. 205. Fig. 206. Fig. 207. Fig. 208. the cloacaa are of sufficient size to admit of the ready extraction of the seques- trum. But in the majority of cases, this cannot be done at once, and the apertures must be enlarged, either with the gouge or the trephine, according to the density of the new case, and amount of room required. Occasionally, when two cloacae are close to one another, the intervening bridge of bone may very conveniently be removed by means of cutting pliers, of different shapes, as in figs. 205, 206, and 208, or by means of a Hey's or a straight narrow saw (fig. 209), and space thus given for the extraction of the sequestrum. Very conve- OPERATIONS FOR NECROSIS. 591 nient pliers, for this purpose, are those represented in fig. 207. They are made by Mr. Coxeter, with gouge ends, and hence may be termed gouge-forceps. I have found them extremely serviceable in many operations upon the bones. Fig. 209. Care, however, should be taken not to remove more of the new case than is absolutely necessary, as the aperture so made in it will not be filled up again by osseous matter, but will be closed by fibrous tissue, and thus the ultimate Fig. 210. soundness of the limb might be endangered. For the extraction of the seques- trum the most convenient instrument is a pair of strong necrosis forceps, well roughened at their extremity, and straight or bent as the case may require (fig. 210). Occasionally the sequestrum is so shaped and placed that it cannot be seized with this instrument; under these circum- stances, it will be useful to drive a screw-probe (fig. 56) into it, by which it may either be extracted, or so fixed as to admit of seizure, and removed by the forceps. In some cases, additional and convenient purchase may be given to the dead bone, by fixing a bone-forceps, such as represented in fig. 211, firmly into it. If the sequestrum is too large to be removed entire through the cloaca, it may perhaps best be extracted piecemeal, having been previously divided by passing the points of narrow, but strong, cutting pliers into the interior of the bone. ^ After the removal of the sequestra, a smooth, hollow cavity will be left in the new case, from the bottom and sides of which blood usually wells up freely, issuing abundantly from the vascular bone, and from the granulating mem- brane lining its interior. Should this hemorrhage be at all troublesome, pressure will always sufficiently arrest it. Lint must then be lightly introduced into the bottom of the wound and the part elevated; a good deal of inflam- mation is frequently set up after these operations, but that must be combated on general principles. If the sequestrum have been a long one, and involve the greater part of the shaft of the bone, it may happen that the new case has not sufficient strength to maintain the limb of its proper length and shape, and that it will bend or break under the action of the forces and weight to which it is subjected. In 592 DISEASES OF BONES. order to prevent this accident, it will be necessary to put it up in light splints or in a starch bandage. After the removal of the dead bone, the fistuhe will speedily close, and the limb eventually regain its normal size and shape. If the necrosed bone be so situated that it cannot be removed, occupying too great an extent and continuing to be firmly fixed, and if, at the same time the patient's health have been worn down by constant discharge, and symptoms of hectic come on; or, if the limb have generally been greatly disorganized by the morbid processes going on in it, amputation must be had recourse to as a last resource. It is especially in the lower third of the femur that these severe forms of necrosis occur, necessitating amputation of the limb. As an idiopathic disease, necrosis of the tibia is rarely met with requiring this operation but when it is the result of bad compound fractures, or of other serious injuries the removal of the limb may become imperative. In acute necrosis, however of the lower end of the thigh or of the tibia, involving the contiguous joints and attended by extensive abscess of the limbs, amputation is imperative. Amputation may also be required in necrosis for hemorrhage from the sinuses and abscesses, the bleeding being either the result of general oozing from their walls, or arising from the laceration of a large arterial trunk by the point of a rugged sequestrum. In other cases, again, removal of the limb may be rendered imperative by the implication and suppuration of a neighboring joint. Resection of the whole of the necrosed bone may, in some cases, be advan- tageously performed; thus, in the case of necrosis of the ungual phalanx occur- ring from whitlow, where, by the removal of the dead bone, the end of the finger may be preserved, so also in necrosis of some of the metatarsal and tarsal bones, resection may be advantageously practised. When the ilium and pelvic bones are affected, it is seldom that any operative measure can be had recourse to with advantage. In some cases, however, if the disease be limited to a portion of the crest of the ilium, or to the tuber ischii, the dead bone may be removed. In these cases it, however, not uncommonly happens that disease of a similar kind exists elsewhere, about the sacrum or spine, that will eventually destroy the patient. In a case in which I removed a portion of the crista ilii for necrosis that was apparently confined to that bone, it was found, on the patient dying some weeks afterwards of erysipelas, that the lumbar vertebras were also diseased. Necrosis of the flat bones, such as the sternum, scapula, and bones of the pelvis, is an excessively tedious process, there being but very little tendency to the formation of the line of separation, and the detachment of the sequestrum, which will continue bare, rough, and adherent for many years. Should it be so situated that it can be removed, it must be excised, even though not detached; but, unfortunately, in the pelvis, it often happens that the necrosed portion is so deeply placed that it cannot be safely excised: here we must leave the patient to the chance of the bone being at length so loosened as to admit of extraction. Necrosis of the cranial bones occurs as the result of injury, of scrofula, or syphilis. In this form of the disease there is the special danger of inflammatory action extending to the brain and its membranes. When attacking the vault of the skull, the necrosis is usually the result of syphilis, is often confined to the outer table, which may exfoliate in large plates, and is less liable than in some other situations to give rise to cerebral disease. When affecting the lower part of the frontal bone, the outer wall of the frontal sinus, or the supraorbital ridge, the disease is generally strumous, and the process of separation is extremely slow; and it will usually be necessary for the surgeon to remove, by means of the trephine, gouge, or cutting pliers, the attached, but rough and dead, bone. When the petrous portion of the temporal bone is the seat of necrosis, death will usually result from encephalitis. When the mastoid process is attacked, the sequestrum will often separate, and may be removed. STRUCTURAL CHANGES IN BONE. 593 Necrosis may affect the alveolar process, the body or the ramus of the lower jaw. In these cases, the dead bone may usually, the separation having taken place, be extracted through the mouth without the necessity of incising the integuments covering it; but, when very extensive, it may require to be removed by external incision. The patella is rarely necrosed. I have, however, met with one instance of primary necrosis of this bone leading to disorganization of the knee-joint, and necessitating amputation. When the ribs are necrosed, abscesses and sinuses will often form to a consi- derable extent on the side of the chest. These must be laid open, and the dis- eased portion of bone scraped away by the gouge. In doing this, care must, of course, be taken that the adjacent intercostal space be not punctured by an unfortunate slip of the instrument,—an accident that is best avoided by pro- tecting the gouge well with the finger. CHAPTER XLII. STRUCTURAL CHANGES IN BONE. The bones are liable to various structural changes, by which their size, shape, and consistence are modified, or in consequence of which they become the seat of tumors of various kinds. Hypertrophy of bone usually results from inflammation of the osseous tissue, but in some cases it may occur apparently without having been preceded by any signs indicative of this condition; it then resembles in character some of the forms of exostosis that will presently be mentioned. Atrophy of bone some- times occurs as a natural result, in old age. In other cases, again, it happens as a consequence of fracture, the nutritious artery of the bone, as has been pointed out by Mr. Curling, having been torn across, and one of the fragments consequently receiving insufficient vascular supply. Atrophy of bone also com- monly occurs from disuse, as is the case in old dislocations. In cases of hyper- trophy, the bone is not only enlarged in circumference, and also perhaps in length, but indurated, becoming specifically heavier. In atrophy, on the other hand, it is thinner, lighter, and more porous than usual, the compact structure disappearing, and the cancellous being expanded. Rickets is a disease of early life, usually being met with in scrofulous children, and never occurring after the age of puberty. In it the structure of the bones is changed, the earthy matter being deficient and the organic material in excess, so that the bone continues to be soft, flexible, and cartilaginous in structure, at an age when its tissue ought to have undergone proper consolidation. It appears to be atrophied, and the cancellous structure to be expanded into cells of varying magnitude, which contain a brownish-red serous fluid. In conse- quence of the change of structure and the loss of firmness in the bones in this disease, considerable distortion of the body takes place. The head early appears large and expanded; indeed, Killian states that the rickets always first appear in the head, the forehead being especially protuberant; according to Mr. Stan- ley, this arises not from enlargement of the cranial bones, but in consequence of the want of development of those of the face; the head thus appearing large from its disproportion to the small face. The shape of the limbs is much changed and distorted, in consequence of their yielding to the pressure of the superincumbent weight; the pelvis becoming contracted, and the thighs and legs 38 594 STRUCTURAL CHANGES IN BONE. bent either forwards or outwards. The joints are usually swollen, the articular ends of the bones appearing enlarged. In early life the chest will be observed to be deformed in a peculiar manner, being narrowed above, where the upper ribs are contracted and pressed in, out expanded below, apparently from the weight of the abdominal viscera, which are often tumefied, and in these cases drag on the lower ribs. As puberty advances, lateral curvature of the spine commonly takes place. In ricketty children there is a general delicacy of appearance, and often a strumous habit of body, though, according to Bokitan- sky, they are not usually tuberculous; if they live, however, past the age of puberty, they may eventually become sufficiently powerful in frame. The treatment of rickets must be conducted on the same general principles that guide us in cases of scrofula; pure air, good food, and plenty of it, regular exercise, and the administration of tonics, especially the preparations of iron, with scrupulous attention to the general habits of life of the child, will generally improve his condition to the utmost limits compatible with the powers of his constitution, and by improving the nutrition of the system tend to the more healthy deposition of osseous matter. In some cases the administration of lime- water with milk seems to be of service in supplying those elements that are required by the system. It is of much importance in preventing deformity in these cases not to allow the child to walk or stand much, but to let it take exercise in donkey-panniers or hand-chairs, and to support those limbs that have a special tendency to become excurvated, with properly constructed steel supports, which will be found of much use, provided they are not too heavy, or interfere with the action of the muscles. Methodical friction should also be employed, so as to stimulate the muscles; as these become more vigorous, their osseous attachments have a tendency to become stronger. Mollities and fragilitas ossium. Osteomalacia. — A very rare but most destructive and dangerous disease of the bones, characterized by softening and fragility of the osseous structure, is occasionally met with. This affection has of late years been studied with much attention by Curling, Solly > Stanley, and Maclntyre, and it is principally from the labors of these gentlemen that we are acquainted with its true pathology. In this disease the bones are bent, their epiphyses swollen, and their shafts broken in various parts of the body. Occasionally, though very rarely, only one is fractured; but in other cases, as in Tyrrell's, there may be as many as twenty-two fractures; or, as in Arnott's, thirty-one. These fractures are unattended by any attempt at the formation of callus. The body becomes singularly and distressingly distorted. On examining the bones after death they will be found to be light, soft, and somewhat gritty; bending, and at the same time readily snapping across; occasionally they are expanded and thickened. This happens especially with the skull, which becomes often con- siderably increased in substance. On cutting the bones, which are soft, and yield something like cartilage, the knife usually encounters a kind of gritty sensation. On making a section of the bones they appear of a deep reddish- brown, or maroon color, and will be seen to contain cavities of various sizes, small or large, but always of a circular or oval shape, and generally filled with an oily, red, and grumous fluid; though sometimes they contain clear serum. On examining this red grumous matter under the microscope, Solly remarks that, as it shows a cell development, it is probably an adventitious morbid product, and not simply fatty matter altered by the effusion of blood into it; and Dalrymple has shown that this material is composed of granular matter, nucleated cells, and a few caudate corpuscles; he therefore believes it to be a disease essentially malignant in its nature, but differing from other malignant affections; for " instead of progressively reproducing and developing themselves without limitation, the new and morbid formations which replace the original and sound structure, seem to have been at an early age of their existence removed RICKETS. — MOLLITIES OSSIUM. 595 by absorption and carried out of the system" (Maclntyre). The bone itself has been found by Solly on microscopical examination to have its laminated structure absorbed, the osseous corpuscles diminished in number, and the Haversian canals enormously distended. In chemical composition the diseased bone has been found by Dr. Leeson to be composed of 18-75 animal matter, 29T7 phosphate and carbonate of lime, and 52-08 of water in every hundred parts. The cause of the complaint seems altogether unknown; it would appear that in many cases it is connected with a rheumatic tendency, as in every case recorded, the affection has been preceded or accompanied by severe pains, or distinct rheumatic attacks. It most commonly, though not invariably, occurs in females, a fact pointed out by Killian, and exclusively attacks adults, commencing even at very advanced ages. One of the most important points connected with this affection is the condition of the urine in it. In all cases that have been recorded, this excretion has been seen to contain large quantities of earthy matter. Solly pointed out that this is the phosphate of lime, which has been absorbed from the bone, and thrown out by the kidneys in the urine; and sometimes the elimination of these matters is so abundant that it forms, as in one of the cases which he relates, a solid calculus clogging up the interior of the kidney. In Dr. Maclntyre's case, the earthy matters of the bone appear to have been, in the first instance, absorbed, and carried off from the kidney by the urine, but afterwards an animal matter of a peculiar and apparently previously undescribed character, was discharged in great abundance. He says, that on adding nitric acid to the urine " a slight yellowish opacity was the first announcement of a change going on in the mixture; this gradually deepened in tint, with increasing consistency of the fluid, till the whole congealed into a bright and somewhat resplendent mass, presenting very much the appearance of a heap of nitrate of urea scales, blocking up the tube. It further resembled that substance in liquefying on the application of heat, and again concreting on cooling, but no crystalline arrange- ment could be perceived, the sparkling appearance being evidently due to numerous air-bubbles entangled in the mass. Perfect redissolution took place when the tube was held for a few minutes in the flame of a spirit-lamp, or plunged into hot water at 160° or 170°, the ordinary coagulating point of albumen; and the fluidity thus acquired persisted under ebullition, however prolonged." (Med. Chirurg. Trans, vol. xxxiii. p. 29.) The symptoms of this disease are, in the early stages, of an extremely obscure and insidious character. The patient complains, in the first instance, of pains of a wandering character about the limbs and trunk; these assume usually a rheumatic character, though they have been observed to be of a much more severe, persistent, and intractable nature, than in any form of that affection. The patient becomes debilitated, unfitted for exertion, and emaciates. Sponta- neous fracture now occurs in some bones under the influence of the most trivial causes; others become bent, and the body consequently greatly mis-shapen and distorted, occasionally in the most wonderful manner. The urine will be observed to present some of the abnormal characters above described, and death eventually results from general exhaustion. The diagnosis of this affection has to be made in the early stages from rheu- matism. This is not so easy, and, indeed, is at first impossible; but after a time, when the peculiar phosphatic condition of the urine, and the fragility or distortions of the osseous system manifest themselves, the true nature of the affection reveals itself. From rickets the diagnosis may usually be pretty readily made, by observing that, whilst rickets is a disease of childhood, osteo- malacia is an affection peculiar to adult or advanced life. The occurrence of severe pains, and the greater amount of distortion, with the tendency to spon- 596 STRUCTURAL CHANGES IN BONE. taneous fracture, which is observed in this disease, is never noticed in ricketty children. With regard to treatment, but little can be done; the administration of tonics, and a general supporting plan of treatment, may arrest for a time the progress of this terrible affection; but when once it is declared, it usually pro- gresses from bad to worse, and at last destroys the patient. Opiates may be employed to allay the pain, and in Dr. Maclntyre's case some temporary advan- tage appeared to result from the administration of alum; but no remedy has appeared to exercise any decided or continuous advantage in this complaint, which there is reason to believe, with Solly, is of a truly malignant character. Tubercle of bone. — The deposit of tuberculous matter in bone plays an im- portant part in many diseases of this tissue in children and young people of a scrofulous habit of body, being a common cause of some of the most intractable forms of chronic osteitis, circumscribed abscess, caries, and necrosis. As tuber- cle is almost invariably deposited in the cancellous structure, it is a frequent cause of those forms of inflammation of the articular extremities of long bones, that terminate in the destruction of the contiguous joint. In the short bones, as those of the tarsus, it commonly leads to caries and necrosis, and forming, as it often does, in the bodies of the vertebrae, it very frequently gives rise to some of the most destructive diseases of the spine, attended by the formation of large lumbar and iliac abscesses. When once tubercle has been deposited in a bone, it usually sets up a low form of inflammation in the surrounding osseous tissue, which rapidly runs into a carious condition, with the formation of curdy pus, in which masses of half-disintegrated tubercle may be seen. If this destructive action takes place with great rapidity, portions of the bone will be found to necrose in small masses, which lie at the bottom of these tuberculous and carious cavities, as may commonly be observed in some forms of strumous caries of the os calcis and head of the tibia. When the tuberculous deposit has been very extensive, and is of a more acute character, it may cause inflammation and disintegration of the whole of the articular end of a long bone, with separation of the epiphysis. These destructive changes may take place with great rapid- ity: I have seen them happen, in a lad whose thigh I amputated for acute tuberculous infiltration of the lower end of the femur, in less than a month from the first occurrence of the complaint, the patient, at the time of the ope- ration, being nearly exhausted by hectic, induced by the abundant discharge from the diseased bone, and from immense abscesses in his thigh. When, on the contrary, the tuberculous matter is deposited in small quantity in an otherwise healthy bone, it may, as it undergoes softening, dispose to the occurrence of circumscribed abscess, at the same time that chronic thickening and condensation of the surrounding bone takes place. It is in consequence of this condensation of the peripheral portion of the bone by the deposit of fresh layers of osseous tissues under and by the inflamed periosteum, and the difficulty that the tuberculous abscess necessarily experiences in traversing these hypertrophied osseous structures, that it is so apt, when deposited in the vicinity of a joint, to work its way through the cartilages into the cavity of the articulation; as on this surface no fresh deposit or condensation of osseous tissue can take place, and consequently no additional obstacle be offered to the onward progress of the tubercle, or rather of the curdy pus into which it has become transformed. The presence of tubercle in osseous tissue thus not only gives rise to destruc- tive changes in the bone and adjacent articulations, but will occasion inflamma- mation and extensive suppuration in the neighboring soft parts; indeed, some of the largest chronic abscesses that form in the body, those connected with diseased dorsal or lumbar vertebrae, owe their origin, in the majority of cases, to the deposit and disintegration of tubercle in the bones. When once tuber- cle in bone has given rise to caries and perforation of the osseous tissue covering TUBERCLE OF BONE. 597 it, together with plastic infiltration, and abscess and sinuses of the soft parts, these conditions will continue in a permanent manner; the fistulous tracks leading down to the bone and the cavities in it, remaining open so long as any tuberculous matter is left at the bottom of them; and in this way the patient may eventually be exhausted by the copious and continuous discharge from these osseous vomicae. In some favorable cases, as the result of natural pro- cesses, and in others by those operations that the surgeon practises for caries, the whole of the tuberculous matter may be disintegrated, and thus eventually eliminated, a true vomica being left in the bone, or scooped out by the gouge, and then the fistulous track, whether in the soft parts or in bone, having no longer this kind of foreign body lying at its bottom, will gradually close, not by the contraction of its osseous walls, which is of course impossible, but by the deposition of a fibrous tissue by which the cavity is occluded. Nelaton has pointed special attention to the pathology of tubercle of bone, and to the important part that it plays in the diseases of the osseous structure. He describes two forms of tubercle in this situation; the first is the encysted variety, which occurs in the form of small masses, of an opaque white or yel- lowish color, contained in the cyst, which is soft, vascular, and spongy, appa- rently of a cellular structure. This variety is stated by Nelaton to be the most common. I have certainly not found it so, but have most frequently met with the infiltrated opaque tubercle. The other form in which tubercle occurs, according to Nelaton, is an infiltration into the cancellous structure of bones. This may be in the form of semi-transparent granulations of a greyish or rosy tint, opalescent and slightly transparent; occasionally, these granulations are firm, so as almost to resemble cartilaginous deposits in the interior of the bone. The osseous structure, in the midst of which this kind of tuberculous matter is deposited, does not appear at first to undergo any material alteration. The other form of tubercle is that in which it is infiltrated as opaque puriform mat- ter of a pale yellow color, soft, and without vascularity (figs. 212, 213). The osseous tissue, under the influence of this disease, often becomes, as Nelaton Fig. 212. Fig. 213. observes, more condensed than natural, the cells being obliterated so as to resemble the compact substance of bone. In some cases it may continue thus chronically thickened and indurated, but in other instances the tuberculous 598 STRUCTURAL CHANGES IN BONE. Fig. 214. inflammation will give rise to rapid and destructive inflammation of the sur- rounding osseous tissue, which becomes excessively vascular, and crumbles down into a carious state, with some necrosed masses intermixed. In other instances. a°ain, as is not unfrequently observed in some of the forms of caries of the spine, or of white swelling, slow suppuration takes place in the interior of the bone, and on the sides or in the centre of the abscesses thus formed, hardened and white ivory-looking masses and knobs of osseous tissue may be seen to be deposited, these apparently consisting of the tuberculous bone that has undergone some special modification of structure. The treatment of tubercle of bone resolves itself into that of its effects. As its existence cannot be recognized except by the changes that it induces in the bone, the treatment must be directed exclusively to these. Thus, if it occasion circumscribed abscess, that must be opened; if caries, the diseased cavity and tissue must be scooped out, or re- moved in accordance with the principles already laid down; and, if disease of the neighboring articulations result, it must be managed as will hereafter be explained. It is of importance, however, to recognize the dependence of these various affections on a tuberculous state of the bone; for, as this is always of a scro- fulous character, it should necessarily occasion the constitutional measures that are employed to be specially directed to the removal of this cause. Thus, good food, sea-air, the administration of iron, of the iodides, and cod-liver oil, will form most important elements in the treatment, without which, indeed, it cannot be brought to a successful termination. The progress of these cases is generally excessively tedious. Stanley gives, indeed, two years as the time required for a strumous bone to recover itself, and in very many instances this period may even be exceeded. In this, as in all other of the chronic inflamma- tory affections of the bone, it is of considerable moment to continue the means of cure until the disease is fully recovered from, for relapse will occur with special readiness in the tubercular affections, if the patient be allowed to use the diseased limb or part too soon. TUMORS OF BONE. Exostosis. — By exostosis is meant the growth of a bony tumor from some of the osseous structures of the body. The causes that immediately give rise to this disease are usually extremely obscure. There can be no doubt that, in some instances, it is predisposed to by syphilis, scrofula, or cancerous affections; and that in other cases, again, it is hereditary; but, in general, it occurs without any distinct or appreciable exciting cause. Exostoses are of two kinds: the one hard and compact, the other softer, and more spongy. The hard, or ivory exostosis, is a structure that differs both in appearance and composition from true bone. It is extremely compact and white, having a granular section closely resembling that of ivory, and presenting somewhat radiating fibres. In chemical composition, it is found to differ from healthy bone in containing more of the phosphate and less of the carbonate of lime, and also in the proportion of animal matters being smaller. This kind of exostosis principally grows from the flat bones, and as it is generally of small size, seldom produces much inconvenience, unless it be by projecting into and compressing important parts; thus, Cloquet relates the case of a tumor of this kind growing from the pubes, and perforating the bladder, and they are TUMORS OF BONE. 599 occasionally found to project into the orbit, or from the inner table of the skull, upon the brain. When these bony tumors are left to themselves, they usually become stationary after a time. In some instances they have been known to necrose, and to slough away, as it were, from the parts in which they are situated. Of this termination Hilton and Boyer relate instances. The spongy, cancellous, or cellular exostoses grow rapidly, often attain a con- siderable size, and are very commonly multiple. When numerous, they will often be found to be somewhat symmetrical in their arrangement. Not unfre- quently they stretch across from one bone to another, bridging over joints, and thus giving rise to anchylosis; in shape, they vary greatly, sometimes being globular, at others spinous. In structure and chemical composition, they are identical with cancellated bone. The symptoms of exostosis are simply those produced by a hard, thick, and slowly-growing tumor, connected with a bone, and pushing forwards the soft parts covering it. In many cases, it produces serious inconvenience by its pressure, either upon neighboring organs or mucous canals, or it may occasion ulceration of the skin lying above it. Treatment. — If an exostosis is so situated as to occasion inconvenience or deformity, it will be necessary to remove it; and as it is a local disease, there is no fear of its returning, provided this be fully done. If, however, the whole of it be not taken away, it may grow again, and Stanley accordingly recommends that if it be so situated, as upon the cranium, that its base cannot be extirpated, potassa fusa or nitric acid should be applied to the part that is left, so as to produce exfoliation of it. The removal of these tumors is best effected by a Hey's or chain saw, or cutting pliers. In some situations, as when close upon joints, or springing from the cervical vertebrae, they cannot be interfered with; and in other cases, as occasionally happens in the neighborhood of the orbit, their density and hardness may be such, that the saw can scarcely work its way through them. There is a peculiar kind of exostosis occurring from the upper surface of the last phalanx of the great toe, pushing up the nail, and giving rise to great inconvenience. This may be removed by exposing its base and cutting it off with a pair of sharp pliers, without amputating the toe. There is a species of bony growth, called osteoma, consisting of a uniform elongated mass of new bone, deposited on some of the osseous surfaces, somewhat resem- bling a node, and differing from ordinary exostosis in not being pedunculated, that does not admit of removal, and is not amenable to any treatment. Enchondromatous, or osteo-cartilaginous tumors are often met with. These have already been described when speaking of enchondroma and its pathology (p. 398), and need not, consequently, be more than adverted to here. They usually require the resection or amputation of the affected bone, according to the attachments and size of the growth; but Stanley states that in some cases, where the cartilaginous tumor of bone is of small size, it may be influenced and eventually dispersed by the local application of iodine and mercury. Cystic tumors of bone of various kinds are commonly included under the terms osteosarcoma and spina ventosa, which terms having also been occasionally applied to various other solid growths, whether of a fatty, fibrous, gelatinous, or cartilaginous character, as well as to various kinds of malignant tumor springing from bones, have occasioned much confusion in the pathology of these affections. The cystic tumors of bone have been well described by Nelaton. They consist of cysts, having various kinds of fluid and solid contents. The cysts may be unilocular, and these are commonly filled with solid matter, or multilocular, and they then contain fluid. The solid masses are usually of a fibrous or fibro-cartilaginous character, filling up completely the cavity in which they are situated, and then attaining a very considerable size. They occur prin- cipally about the jaws and articular ends of long bones, especially the humerus, the femur, and the tibia. The cysts with fluid or semi-fluid contents attain a 600 STRUCTURAL CHANGES IN BONE. Fig. 215. Cystic tumor of lower end of femur. much larger size than the last, being often met with as large as a cocoa-nut or a foetal head. On a section being made of them, they are found to be com- posed of a multilocular cyst, each cavity havin«' distinct walls, and often communicating with others. The fluid contained within these cysts is of various characters, thin and serous, sero- sanguinolent, viscid, or dark-colored, often asso- ciated with masses of fibrous tumor, appearing as if it proceeded from the central softenin» of these large growths. The same situations are affected by the compound as by the single cysts, but they are also met with in the shafts of long bones. From whatever part they pro- ceed, their walls are composed of expanded bone, not uniformly thinned, but thickened and noduled at various parts, whilst it is per- forated at others (fig. 215). These cystic tumors principally occur in adults, being rarely met with in children. They constitute smooth, round, or oval growths, increasing slowly but steadily, with little or no pain, the skin covering them being of the normal color, and the veins usually blue, en- larged, and tortuous. When a certain size has been attained, so that the shell of bone is ex- panded into a very thin lamella, and before it is perforated, pressure on the tumor occasions a peculiar crackling or rustling noise like that produced by pressing together a broken egg-shell, or the crackling of tin-foil. Under this the elasticity or even semi-fluctuation of the tumor may be felt. This fluctuation is particularly marked after a time, when the osseous envelope has become still more expanded, or is partially or wholly absorbed. Treatment___When the contents are solid, there is usually no means of ridding the patient of the tumor, but by the removal of the whole growth; by excision, if it is favorably situated for such procedure, as in the jaws; by ampu- tation, if in the limbs. When the contents of the tumor are fluid or semi-fluid, it must, if large, be treated in the same way as the solid growths are; but, if small, or if of moderate size, so as not to have materially affected the integrity of the bone, then it may suffice to remove one side of the wall of the cyst by the trephine or by excision; and then stuffing the cavity with lint, allowing it to granulate, and its walls to contract. This plan has proved especially success- ful in some of the cystic tumors of the lower jaw. And I have had occasion to practise it with success in a small cyst forming in the outer condyle of the humerus. Hydatids---Cavities are occasionally, but very rarely, found in bones, in which large numbers of hydatids are lodged; according to Stanley, both the acephalocyst and the cysticercus cellulosa have been found in this tissue, but most frequently the first. In these cases a cyst forms in the bone, which becomes thin and expanded, resembling the ordinary fluid cyst tumor, but which, on examination, is found to contain these entozoa. The treatment, as Mr. Stanley observes, must depend on the situation and extent of the disease; if it is a long bone that is affected, and that is much expanded, amputation must be had recourse to; if a flat bone, the cavity must be scooped out, and dressed from the bottom with stimulating applications, so as to get it to fill with healthy granulations. Malignant osteoid, osteo-cancer or osteo-cephaloma are true malignant tumors OSTEO-CANCER. 601 of bone, constituting very serious but not very rare forms of cancer. Two distinct forms of cancer of bone are included in this disease. In one form the morbid growth is central, springing from the medullary canal; in the other it is peripheral, being attached to the compact osseous substance. Encephaloid of bones is harder and more fibrous-looking than the same affection elsewhere. The cancer-cell also is not so well marked, and indeed may be absent altogether. In the central cancer of bone, the tumor is found to grow in the substance of, or to spring from, the interior of the medullary canal of the bone. It is usually situated at or about the articular ends, expanding the bone, which be- comes completely enveloped and incorporated in the structure of the growth, either in the form of osseous rays diverging from the centre of the tumor, or more rarely as a thin shell of bone surrounding the mass, as in the more simple growths springing from this tissue. Under either circumstance it is important to bear in mind that this form of disease is never localized, but always invades the whole of the bone; the freedom of communication between the upper and lower ends of a long bone is so great, that, as has been shown by Richet, water injected at one end exudes in a few seconds at the other. Hence the juices of a malignant structure might easily traverse the whole length of the bone, and we accordingly find on examining the osseous tissue at a distance from the tumor, that there are red patches in it here and there indicative of its infiltra- tion with the morbid structure. In the peripheral form of cancer of bone, which is probably the most common variety, the osseous tissue is not so completely invaded; for, although the dis- ease may be situated upon, or be in intimate contact with, the outer layers of the bone, which are incorporated in it, it does not extend into the cancellous tissue, or the medullary canal. The tumor appears to spring from the perios- teum, and after removal and maceration, stalactitical projections and radiating fibres may be traced into it from the outer layers of the bone. In this form of osteo-cancer, the muscles that are attached to the affected portion of bone will often be found to be extensively infiltrated with cancer-cells. These tumors, whether central or peripheral, are chiefly of the encephaloid species of cancer, and are met with in all stages of development and of decay. Occasionally, some colloid, and more rarely melanotic matter is intermixed; but scirrhus, I believe, is never found in bone. They most frequently occur in the head of the tibia and the lower end of the femur; occasionally in the humerus and in the jaws, more especially about the antrum. It is a remark- able fact, long ago pointed out by Petit, and more recently insisted on by Richet, and which I have often had occasion to verify, that although the epiphysis may have been completely converted into encephaloid matter, the cartilage of incrustation and of the neighboring joint (fig. 217) never becomes implicated; and this, although the growth may eventually involve and include the whole of the rest of the articulation, by extension to the capsule and its soft parts. When internal organs become secondarily affected in these cases, the deposit will generally be found in the lungs. The symptoms of these tumors are as follow: there is a rapidly-growing enlargement of the bone, usually with much lancinating pain, having a globular shape, feeling elastic, and sometimes semi-fluctuating. The skin covering it, at first pale, with numerous reticulated and blue tortuous veins, afterwards becomes discolored, being eventually implicated in the morbid mass. In some cases fracture of the bone takes place at the affected part (fig. 216); the neighboring tissues are speedily contaminated, the lymphatic glands become enlarged, cancerous cachexy sets in, and the patient eventually sinks. In other cases, again, the disease being central, the progress, especially in the early stages of the disease, is less rapid, though it at last develops itself with fear- ful violence. So long as the disease is confined within the walls of the bone, it develops itself but slowly, and does not show much disposition to affect the 602 STRUCTURAL CHANGES IN BONE. constitution. I had lately a patient under my care, a man whose thigh I am- putated for cancer of the head of the tibia, that had existed for four years Fig. 216. Fig. 217. Osteocephaloma of the head of the hume- rus with spontaneous fracture of the shaft, in which I amputated successfully at the shoulder-joint. Section of tumor — upper end and head of humerus destroyed, but carti- lage of incrustation unaffected. Tumor divided by white vertical lines,—the pe- riosteum; inside which only were the osseous spiculse found. without contaminating the neighboring parts, whose constitution appeared sound, and who made a good recovery. But when once the soft parts become engaged, the system is speedily contaminated. In some instances, pulsation of a thrilling kind, with or without a blowing murmur, is distinctly perceptible, especially in an advanced stage of the affection, when the vascularity of the tumor is greatly increased. The diagnosis of osteo-cancer has to be made from other tumors of bone, and from aneurism. The malignant growths of bone may readily be confounded with those various forms of non-malignant disease that are commonly included under the term spina ventosa. In making the diagnosis, we may reasonably come to the conclusion that the growth is cancerous, if it occur in early life before puberty, or between this period and the early adult age; if it increase with great rapidity, and with much pain, especially of a lancinating character; if, to the touch, it present a somewhat diffused pulpiness, with much elasticity, great tension, and, at points, a semi-fluctuating feel; and, more especially, if the veins are greatly enlarged and tortuous, the neighboring lymphatic glands involved, and cachexy ultimately setting in. These conditions differing from the slow growth, the more circumscribed character and more solid feel of the non-malignant tumors, which have no tendency to the implication of neigh- boring structures, and which occur at later periods of life, usually enable us to make the diagnosis. There is one tumor, however, viz., enchondroma, which OSTEO-CANCER. 603 occasionally in the rapidity of its growth, closely resembles the malignant dis- eases. Here the diagnosis is confessedly extremely difficult, though the more solid character, the less degree of elasticity, and the absence of lymphatic en- largement, or implication of contiguous tissues, will often enable us to establish the true nature of a tumor before its removal. The diagnosis from aneurism is necessarily unattended by any difficulty so long as the sac is pervious to fluid blood, and presents the characters that are met with in this condition. But if the sac have become consolidated by the deposit of stratified lamina, and thus have assumed the characters of a solid tumor, it may readily enough be mistaken for a tumor springing from the osseous structures, and amputation has occasionally been performed on this sup- position. In these cases, however, the history of the progress of the disease will do more to elucidate its true nature than anything else, attention being more especially paid to the early symptoms of the tumor, when the aneurism was still filled with blood. Treatment. — No means are of any avail in cases of osteo-cancer except the removal of the part diseased by amputation or excision. These operations are however not very promising, as there are few forms of cancer in which the disease returns more rapidly in a secondary manner, than that of the bones. The rapidity of recurrence will, however, greatly depend upon the form of the disease, the time at which amputation is performed, and on the part where it is practised. It should always if possible be had recourse to in the earliest stage of the disease, before glandular or constitutional infection has set in. If the glands are enlarged, and cachexy has already occurred, little can be expected in the way of ultimate cure, but yet I have known cases in which, even under these unfavorable circumstances, the patient has made a good recovery; his life having been prolonged for months. I believe that return is much more speedy and certain after amputation in the peripheral than in the central form of osteo-cancer, provided in the latter the whole of the bone has been removed, owing to the more extensive contaminations of the soft parts in the former than in the latter case. The selection of the line at which amputation should be performed is of great importance, and the result will materially depend upon the judgment displayed in this. If the limb be removed in the continuity of the diseased bone there must necessarily be a great probability of the very rapid return of the morbid action in the stump, and this probability amounts to a certainty in those cases in which the disease is central, and in which the whole of the medullary canal and cancellous structure are implicated, and infiltrated with cancer. In cases of peripheral osteo-cancer, this return in the same bone may not take place; indeed, I have seen one case of the kind in which the disease affected the lower end of the tibia, and that bone was amputated in its upper third; in this case, after a lapse of some months, fatal recurrence of the disease took place in the pelvic bones, but not in the stump. As, however, the peripheral is more rare than the central form of the disease, and as there are no means of ascertaining the precise kind before removal, the rule, I think, should be definite to amputate at or above the next joint; at the hip-joint, in cancer of the femur; in the thigh, for that of the bones of the leg; and at the « shoulder, when the upper arm is affected. Where the lower part of the femur, however, is involved, amputation through the trochanters may sometimes be substituted for disarticulation at the hip joint, the latter operation being so formidable and so fatal that the surgeon may think it advisable not to subject the patient to so serious a risk; or the amputation might be performed through the trochanters, and then the head of the bone extirpated from the acetabulum. In this way the severity of the operation and the extent of incised surface would be lessened, whilst the whole of the diseased bone would be removed In the peripheral form of osteo-cancer, however, the muscles inserted into the 604 STRUCTURAL CHANGES IN BONE. affected bone often become speedily contaminated by the disease, and this con- tamination may spread widely through the substance of any particular muscle. Hence I think the rule in these cases should be to amputate not only above the diseased bone, but, if practicable, above the origins of the muscles in the neigh- borhood of the disease; thus if there be a malignant tumor of the bones of the forearm, amputation should be done above the humeral attachments of the mus- cles of the forearm. The propriety of excision of some bones, as of those of the face, in this dis- ease must depend on whether the morbid deposit is limited to the structures that can be excised. This operation can rarely be advantageously practised in malignant tumors, there being in general too great an implication of the soft structures in the neighborhood to make such a proceeding justifiable. Sanguineous tumors are occasionally met with in bones; according to Stanley they are of two kinds. 1st. Those in which the tumor is composed of a vas- cular substance, having the general characters of erectile tissue, and bearing on section a close resemblance to certain nevi (fig. 218). This tumor may be removed without the liability to reproduction. The 2d form of sanguineous tumor consists of a cyst formed in the cancellous structure of a bone, and con- taining either fluid or coagulated blood. According to Stanley, this tumor ex- pands the osseous walls, and will gradually cause ulceration of the skin and pro- fuse hemorrhage. The treatment consists in the amputation of the limb, or the excision of the affected bone, as was successfully done by Travers, who removed a clavicle that was the seat of this disease. Aneurism by anastomosis of one of the parietal bones. pulsation communicated to them from a neighbor- ing artery; but the true pulsating tumors of bone owe their pulsations to some inherent peculiarity of structure, which appears to consist either in the develop- ment of a vascular tissue of abnormal cbaracter, or else in the simple enlarge- ment and dilatation of the vessels of the bone. In the first, and most frequent class of cases, those in which new tissue is developed in the osseous structure, we usually find them partake of an encephaloid character; a creamy, curdy, or brain-like, soft and very vascular mass is formed as an essential and principal constituent of the tumor. This might consequently with propriety be termed an encephalo-osteo-aneurisma. This abnormal mass will be found to present every shade of transition from true encephaloid cancer to a purely vascular tissue of an erectile character. In the second, and more rare form of the dis- ease, a structure is developed in the bone which originally, and, in many cases OSTEO-ANEURISM. 605 throughout, is a vascular, erectile growth, closely resembling capillary nevus in its structure, composed of an infinity of blood-vessels, interlacing in every pos- sible way, so as to form a soft, reddish-yellow tumor. In other cases, again, a hollow cavity is formed in the bone, scooped out of the cancellous structure and filled with blood, which is partly liquid and partly coagulated, and into which arterial branches freely open. The shell of bone surrounding this cavity is very thin and expanded, being usually absorbed at one point, where it often becomes at last perforated. This is the form of disease that constitutes the true aneurism of bone. These various kinds of pulsatory tumor of bone have been met with in almost all parts of the body; most commonly the cancellous articular ends of the long bones, more particularly of the tibia, the radius, the humerus, and the femur, have been found affected. The pelvic bones are also not unfrequently the seat of these growths, and they have been encountered in the cranium, the ribs, and indeed in connection with most of the osseous structures. In its early symptoms an osteo-aneurism closely resembles the ordinary forms of spina ventosa, being oval in shape, uniform, and elastic to the touch, grow- ing slowly, without enlargement of the veins or discoloration of the skin, cha- racters that it possesses in common with most other tumors of bone. The special signs by which it is individualized, however, are its pulsation and bruit: the pulsation is very distinct, superficial, and commonly of a thrilling character; in other cases it is directly impulsive, and distinctly expansive; the bruit is most usually soft and blowing, but not unfrequently harsh, loud, and whizzing. In some cases the bruit is absent, though the pulsation continues distinct; this, according to Nelaton, is most frequently the case in true osteo-aneurisma. In the pulsating encephaloid form of the disease, I have heard the bruit peculiarly loud, rough, and superficial. On compressing the main artery leading to the part of the limb in which the tumor is situated, all movement and bruit com- monly cease in it, and it lessens in size. By pressing upon the tumor when it is thus diminished, it will commonly be found to have a bony margin, with a central depression, more especially in those cases in which there is no encepha- loid entering into its composition, the growth being apparently composed of erectile and expanded osseous tissue, filled with fluid blood. In some cases, however, the tumor is fed by several arterial branches, which may be felt dis- tinctly pulsating under the skin. This is more particularly the case when it occurs upon the bones of the pelvis and the scapula, and then the bruit and pulsation cannot be made to cease in it. All these signs are commonly some- what intermittent, appearing perhaps in the earlier stages of the disease, and disappearing as it advances; or the reverse may occur, the pulsation and bruit becoming distinct as the disease increases in size and meets with more resist- ance in its outward growth. Diagnejsis. — It is of considerable importance in many cases to diagnose the different forms of pulsating tumor of bone from one another, some being of a truly cancerous character, whilst others appear to consist of simple expansion of the vascular element of the bone, with atrophy of its osseous substance, and consequently the prognosis also in the two conditions is very different. The true osteo-aneurism has so many signs in common with the pulsating encepha- loid tumor of bone, that in many cases it is almost impossible to effect the diagnosis; yet it is well to bear in mind that the malignant form of the disease is not unfrequently multiple, occurring, with pulsation and bruit, in more situ- ations than one; thus I have seen growths of this kind, with their signs well marked, springing both from the pelvis and ribs. The true osteo-aneurism is only met with in the articular ends of long bones, whereas the malignant dis- ease, though commonly occurring in these situations, is also frequently found seated in other parts of the body. Besides these, there are two conditions which, in many cases, will enable the surgeon to determine that the pulsating 606 STRUCTURAL CHANGES IN BONE. tumor is an osseous aneurism; viz., the absence of all bruit, though the pulsa- tion be distinct, and the detection by firm pressure, and after the tumor has been diminished by the compression of the artery leading to it, of an osseous margin around its depressed centre. From ordinary aneurisms, the diagnosis of these affections is, in many cases, attended by almost insuperable difficulties. So great are these, that there are many cases on record in which the most experienced surgeons of the day have ligatured arteries for tumors that were supposed to be aneurismal, but which have turned out to be pulsating growths connected with bone. The principal points to be attended to in effecting the diagnosis, are the situation of the tumor, which may occur away from the ordinary sites of aneurism, in parts of the body where there is no vessel large enough to give rise to such a disease, as for instance, about the head of the fibula or the side of the pelvis. Then, again, its incorporation with the subjacent bone, the want of a distinctly limited and circumscribed outline, and the existence in many cases of plates of bone in the wall of the tumor, giving rise, perhaps, on pressure, to the peculiar rustling or crackling sound characteristic of bony growths, will enable the sur- geon to come to a conclusion as to the true nature of the tumor. In this he will be further assisted by its giving on compression a soft, doughy, or spongy feel, or appearing as a depression surrounded by an osseous margin. In many cases also the less impulsive character of the beat of the tumor, the peculiar shrill and tremulous whizz in the pulsation and bruit, will throw much light on the nature of the disease. But yet it cannot be doubted, that when tumors of this kind occur in some of the ordinary situations of aneurism, as about the brim of the pelvis, and in the popliteal space, that the diagnosis is surrounded with difficulties that no amount of surgical skill or tact may be able to over- come. From ordinary tumors of bone, the existence of pulsation and bruit will always suffice to distinguish the growths under consideration. Treatment. — Incision into a pulsating tumor of bone, or any attempt to re- move it without its osseous connections, is clearly contrary to the rules of good surgery; and when it has been practised, the hemorrhage has been of the most alarming and dangerous character. Resection has been had recourse to in some instances, as when the disease has been seated on the cranial bones, but without success. Liston, in a tumor of this kind growing from the scapula, which he called " an ossified aneurismal tumor of the sub-scapular artery," excised the greater portion of the bone from which it sprang; but fungous growths reap- peared in the wound, by which the patient was at last exhausted. When the disease has proceeded to such an extent as to produce extensive alteration in, and destruction of the tissue of the bone affected, amputation of the limb is the only resource left to the surgeon. This operation is also called for in those cases in which the disease returns after other means, such as the ligature of the artery, have been practised. In these cases, if the disease partake at all of the encephaloid character, the limb must be removed at a point above the affected bone. The result of the ligature of the main artery leading to the tumor depends greatly upon the nature of the growth. When it is partly composed of en- cephaloid or other solid tissue, but little good can result from this proceeding, the tumor continuing to increase by an inherent growth, that will continue as long as the vitality of the limb is maintained; and we accordingly find that in all such cases in which this operation has been practised, the progress of the tumor has either not been retarded, or if the pulsations have been stopped, and its size lessened for a time, the activity of the symptoms has speedily re- turned, and amputation been rendered necessary. When, however, the tumor has partaken more of the characters of true osteo-aneurism, then a more favor- able result has followed the ligature of the main artery of the limb. In a cat;e of this kind seated in the radius, in which Roux ligatured the brachial artery, SYNOVITIS. 607 a complete cure resulted. The same also occurred to Lallemand; and in a patient of Dupuytren's, there was no return of the disease for six years, when it recurred, and amputation became necessary. These results are sufficiently satisfactory to justify the surgeon in having recourse to the ligature, or perhaps the compression of the main artery of the limb, in those cases in which the tumor could be ascertained not to partake of the nature of encephaloid. CHAPTER XLIII. DISEASES OF JOINTS. The various joints of the body may become the seat of inflammatory affections of an acute or chronic character, of strumous disease, or of various other morbid conditions, such as more or less permanent rigidity, or anchylosis, the formation of foreign bodies within their cavities, or their malignant degeneration. In studying these various articular affections, it must be borne in mind that a joint is composed of a number of different tissues, of synovial membrane, cartilage, ligament, bone, and capsule, or investing fibrous expansion. In any of these structures the disease may primarily begin, though eventually the morbid action often spreads to other tissues besides that which was originally involved. The merit of having been the first to point out the true mode of studying these affections in reference to the different structures in which they have originated, and to have set aside that coarse pathology which, under the general terms of " arthritis" and of " white swelling," confounded together these various diseases, is certainly due to the labors of Sir B. Brodie. SYNOVITIS. Inflammation of the synovial membrane, the most common perhaps of all the articular affections, may be acute, subacute, or chronic in its characters. What- ever form it assumes, synovitis usually results from exposure to cold, especially in rheumatic or syphilitic constitutions. In these cases it commonly happens that more joints than one are implicated at the same time; and the affected articulations are most frequently those that are most exposed by the thinnest covering of soft parts, and by being especially subjected to transitions of tem- perature, such as the knees and ankles. Injuries of joints, as blows, bruises, wounds, or sprains, will also frequently occasion this inflammation; but when arising from this cause, it is seldom of an unmixed kind, being usually associated with inflammation of the other textures that enter into the composition of the articulation. As uncomplicated acute synovitis is never a fatal affection, it is seldom that we have an opportunity of studying its pathology. It would, however, appear from the result of the examination of joints in cases of synovitis from injury, as well as from the result of experiments of Richet, Bonnet, and others, who have induced traumatic synovitis in animals, that there is in the first instance an in- flammatory congestion and vascularity of the membrane, attended by loss of its peculiar satiny polish. The synovia is then increased in quantity, as well as altered in quality, becoming thin and serous, and after a time intermixed with plastic matters that are poured out with it. If the disease progress favorably, these products are more or less completely absorbed. If, however, as is more 608 DISEASES OF JOINTS. rarely the case, the inflammation goes on to an unfavorable termination, the vascularity and swelling of the synovial membrane increase, until at last it becomes so turgid and distended with blood and effused fluids, that a kind of chemosis of it results; a thin, purulent-looking fluid, composed of granular corpuscles floating in a serous liquid, is poured out, and disintegration, with thinning and erosion of the cartilage, and probably complete destruction of the joint, ensues. In other cases, granulations are thrown out on the looser por- tions of the membrane, which, becoming injected with blood-vessels, constitute fringed and villous membranous expansions, lying upon the subjacent, disinte- grated, and eroded cartilage. The termination of synovitis will depend mainly on its cause. When of a simple uncomplicated character, arising, as the result, perhaps, of rheumatic influences, it will in most cases terminate in complete resolution. In other instances, however, plastic matter may be thrown out, that either assumes the form of warty vegetation or concretions within the joint, or of bands stretching across its interior, or incorporated with its capsule, occasioning more or less per- manent stiffness. When synovitis arises from wound it usually goes on to sup- puration within the joint, superficial erosion or disintegration of the cartilage, and eventually, if the limb be not removed, to complete disorganization of the interior of the articulation, and to more or less complete anchylosis. The same happens in the puerperal inflammations of joints, and in those that arise from pyemia, in which cases the morbid action commencing on the synovial membrane extends downwards to the cartilages, eventually leading to destructive disorgani- zation of them. The symptoms of synovitis consist of pain and heat of the joint, with disten- sion and fluctuation of it. If it be large and exposed, the pain is severe, espe- cially at night, being greatly increased by moving or pressing upon the articu- lation ; it is usually sharp, but when the disease occurs in rheumatic or gouty constitutions, of a gnawing character. In purulent synovitis occurring from pyemia, it is usually very superficial, indeed almost cutaneous. On laying the hand on the joint it will be felt to be hot. The swelling of the affected joint is considerable, and evidently depends on the accumulation of fluid within the synovial sac, the extreme outline of which is rendered apparent by the tension to which it is subjected. Thus in the knee it rises up high in the thigh under the tendon of the quadriceps extensor, in the elbow under that of the triceps. There is but little if any effusion into the surrounding tissues, and hence the outline of the joint can be distinctly felt, and undulation perceived in it. The limb is usually semiflexed, as giving the patient most ease, and the joint cannot be moved. The constitutional febrile disturbance is tolerably severe, especially if the affection occur in a rheumatic constitution. The disease, at first acute, may terminate in a subacute or chronic form; or subacute at its commencement, it may fall into a chronic condition. Chronic synovitis is characterized by all the symptoms of the acute variety of the disease, but in a less severe degree. The swelling and weakness of the joint are the most conspicuous local conditions. In some cases, the swelling from accumulated serous fluid is so considerable as to constitute a true dropsy of the joint, hydrar- throsis. This accumulation of fluid, partaking in various degrees of the charac- ters of serum and synovia, is usually preceded or accompanied by evidence of synovial inflammation; but, though this generally happens, it is not invariably the case. Richet, in particular, has recorded instances from which it would appear that inflammation is not a necessary, or invariable accompaniment of the affection, the synovial membrane being indeed preternaturally white, and looking as if it had been washed or soddened; and though these cases are rare, those that commonly present themselves to the surgeon being of a decidedly inflam- HYDRARTHROSIS.— SYNOVITIS- 609 matory character, yet their occasional occurrence is sufficient to establish the existence of a passive, as well as an inflammatory form of the disease. The presence of an abnormal quantity of fluid in the joint is always readily perceived by its fluctuation and undulation, by the deformity that it produces, and by the peculiar shape that it communicates to the part. Thus in the knee, which is the most common seat of this affection, the patella will be felt to float, as it were, on the subjacent liquid; and the capsule of the joint projects dis- tinctly in three situations, viz., on either side of the ligamentum patellae, and above that bone. In the elbow, there is a soft and fluctuating swelling on either Bide of the olecranon, and under the tendon of the triceps; and in the shoulder there is a general soundness and distension of the articulation. It is said, that in some cases, the distension of the joint has been so great, that the synovial membrane has been ruptured, and the fluid poured forth into the surrounding cellular tissue. In these cases, it is probable, however, that some destructive change in the synovial membrane preceded its rupture. The chronic subacute synovitis and hydrarthrosis usually terminate favorably; but, occasionally, more particularly in strumous constitutions, the disease runs on to suppurative destruction of the joint. This, however, is rare, but yet its occurrence, in some instances, should make the surgeon careful not to confound the fluctuation of the serous accumulation with that of the purulent collection. In the latter instances there will always have been the precursory symptoms of inflammation. The treatment of synovitis depends partly on the severity of the symptoms, and partly on the cause of the disease. If the inflammation be acute and arise from injury, it requires to be actively treated by venesection, if the patient is young and strong; but in all instances by the free and repeated application of leeches to the inflamed articulation, followed by fomentations and accompanied by perfect rest of the part on a splint, or on pillows properly arranged. In some instances the cold irrigation will be found to be of essential service; at the same time saline purgatives with antimony must be given, and the patient kept on a low diet. If the disease is of a rheumatic character, leeches must be applied, followed by hot fomentations, and rest of the part in the elevated position; at the same time, colchicum, with salines, if there be much febrile disturbance, and if there be much pain at night, in combination with Dover's powder, should be adminis- tered. In some instances, where colchicum disagrees, great benefit will result from the administration of Dover's powder and calomel, in small but frequent doses. When the disease is of syphilitic origin, leeches are not often required; but the application of blisters, followed by calomel and opium, will be attended with marked success. When the synovitis is of a subacute or chronic character, the same principles of treatment must be adopted, modified according to the intensity of the affec- tion. In these forms of the disease, rest is perhaps the most important element in its treatment, everything else proving nugatory unless this be attended to; the limb is usually best fixed by leather splints, buckled on so that they may be removed in order to make the necessary applications to it. In these cases repeated blisterings over the whole of the joint constitute perhaps the most use- ful local means that we possess; in a more advanced stage, counter-irritation by means of stimulating embrocations, together with douches, either of warm sea- water or of some of the sulphurous springs, such as those of Harrowgate, Aix, or Bareges, will prove most useful; and when all inflammatory action has been subdued, and weakness of the joint merely is left, this should be properly strapped with soap-plaster, spread upon leather. Among the internal remedies likely to be of most service, may be mentioned the iodide of potass, either alone, or in some bitter infusion. In hydrarthrosis, rest and repeated blistering will usually promote the removal 39 610 DISEASES OF JOINTS. of the fluid. In addition to this, the employment of pressure and friction, with absorbent remedies, as the iodine or mercurial ointment, conjoined with the in- ternal administration of the iodide of potass, or a mild mercurial course, will often procure the absorption of the fluid. If these means fail, we have a very powerful means of cure at our command in the subjection of the joint with tinc- ture of iodine. This plan, a sufficiently bold one, has been much employed in Paris by Jobert and Velpeau, and in Lyons, by Bonnet. These surgeons use the tincture diluted with two or three parts of water. A small trochar is intro- duced into the joint, a moderate quantity of the serous fluid is let out, but not all, and then a corresponding quantity of the iodine solution is thrown in; and after being left for a few minutes, allowed to escape. Inflammation of the joint, which is a necessary result of this procedure, comes on. This is then treated by ordinary antiphlogistic means, and, according to the statements of the French surgeons, has in no case been followed by any serious consequences, but in several instances by a complete cure without anchylosis; a new and healthy action having been imprinted on the synovial membrane. The mode of treat- ment does not appear as yet to have met with much support in this country, yet it certainly deserves a trial, though it should not lightly be had recourse to, as it is evident that the induced inflammation might exceed the expected limits. After dropsy of the joint has been removed, the articulation is usually left weak for some length of time, in consequence of the stretching to which its ligaments have been subjected; here cold douches and an elastic bandage will constitute the best modes of treatment. ARTHRITIS. By arthritis, is meant inflammatory disease of an acute or chronic kind, of the whole or greater part of the structures that enter into the formation of a joint. This affection may commence in the synovial membranes, and then spread to the other articular tissues, or it may begin in the cartilages or bones, and in some rare instances it may perhaps take its origin in the fibrous capsule sur- rounding the articulation ; whether it can ever commence in the ligaments is a question that is not as yet satisfactorily determined. In arthritis, the principal changes are undoubtedly found to take place in the cartilages, at the same time it must not be supposed that all morbid appearances that are found in these structures are the result of inflammation, as erosion and absorption of their tissue may take place, independently of any diseased action. The long-continued disuse of a joint, as in the treatment of fractures, may occa- sion this; and in old people it is very common to meet with a porcellanous or ivory-like deposit on the articular ends of the bones, which, however, does not prevent the joints being used, though it may occasion stiffness and pain in them. According to Quekett this porcellanous deposit is of two kinds, one consisting of unorganized earthy matter; the other, of true bone, having the Haversian canals filled with phosphate of lime. In acute arthritis the cartilages are usually found ulcerated and eroded in patches of varying size, exposing bone, which is rough and vascular. The remains of the cartilage are softened, inelastic, opaque, and thickened, and separate easily from the subjacent bone, which can be felt rough and grating. The synovial membrane is usually thickened and very vascular; the vascu- larity being most distinct about those parts, where the erosions and grooves in the cartilage are deepest, and often assuming a dentated or fringed appear- ance. In other parts, especially about the circumference of the joint, masses of plastic matter are deposited underneath, and upon the synovial membrane; these are smooth and semi-transparent, having a somewhat fatty look; the ligaments are relaxed, vascular, and softened, and the interior of the joint filled with thin, flaky, and light-colored pus. The capsule and the cellular tissues PATHOLOGY OF ARTHRITIS. 611 around are thickened, and either infiltrated with pus, or clogged with the same kind of plastic matter that is seen in the interior of the joint. The articular end of the bone is enlarged, soft, and vascular; and in strumous cases may be the seat of Fig. 219. tuberculous infiltration (fig. 219.) The changes that take place in the carti- lages in this disease have excited much atten- tion amongst surgeons, and a good deal of difference of opinion exists as to the mode in which they are induced. Many surgeons hold the doctrine that cartilage being extra- vascular, the changes that take place in it are accomplished through the medium of the contiguous synovial membrane or bone, and consequently are secondary to disease of these tissues. We may, I think, conclude -that this disease of cartilage may arise in three ways: 1st. Through the medium of the synovial membrane; 2d. Through the medium of the subjacent bone; and 3d. By means of changes taking place in the cartilage itself. 1st. The destruction of cartilage, as the result of synovial disease, may best be studied in cases of wound of a joint. In these cases it will be found, if the joint be examined before complete disorganization of it has oc- curred, that the diseased action spreads from the synovial membrane, where it is most in- tense, downwards into the substance of the cartilage, which, superficially diseased, becomes more healthy the deeper the examination of it is carried. Immediately under the swollen, gelatinous-looking, brightly-injected synovial membrane, the cartilage will be found to be reddened, roughened, and softened. On examining a thin slice of this, it will be found to be composed of granular matter and nuclei of cells whose walls have disappeared. At a little greater depth than this it will present an opaque matrix, with cells, some perfect, others imperfect or disintegrating, and below this level we shall come to healthy white cartilage, with clear matrix and well-formed cells. The disorganization of the cartilage will eventually go on to its complete removal, and to the exposure of bare and roughened bone. It is in this way that destruction of joints as the result of punctured wounds, pyemia, or puer- peral inflammation, results. Aston Key advocated the doctrine that a peculiar disease was set up in the synovial membrane by which a fimbriated or fringed vascular network or tissue was formed, by means of which the cartilage was absorbed; and that as this membrane extended, so did the removal of the cartilage go on. , That an appearance of this kind in inflamed joints is of common occurrence is doubtless the case, but Goodsir has shown that Key erred in attributing the disintegra- tion of the cartilage to this membrane; for he states that a fibrous tissue forms in a diseased joint as the result of the disintegration of the cartilage, and that this, which is connected either with the synovial or osseous surfaces, speedily becomes vascular. So far, therefore, from being the organ by which the carti- lage is removed, it is the result of prior disease in this structure. At the same time it cannot, I think, be doubted that a villous injected state of the synovial membrane will modify the nutrition of the subjacent cartilage in such a way, that disintegration, erosion, and apparent ulceration of it will ensue. 2d. Disease of cartilage primarily dependent on morbid action in the sub- 612 DISEASES OF JOINTS. jacent bone is, I believe, one of the most frequent modes of the disorganization of joints in strumous subjects, and most certainly leads to those rapidly destruc- tive affections of joints, in which amputation or excision is required. In these cases, either as the result of violence, or from constitutional causes, the articular ends of a bone, or the whole of a bone if it be one of the tarsal, becomes congested, inflamed, carious, or necrosed, sometimes infiltrated with tubercle. (Fig. 220, a.) In consequence of this disorganization of the osseous tissues, the incrusting carti- lage becomes detached, its under or at- tached surface softened, and at last per- '"" foration takes place. (Fig. 220, b.) This process of disintegration and at last per- foration and erosion of the cartilage, takes place in a direction from below upwards. So soon as perforation occurs, the whole of the interior of the joint becomes acutely inflamed and suppuration is set up in it, the ligaments loosen, and complete disor- ganization ensues (fig. 220). On examin- ing the diseased patch of cartilage in such cases as these, it will be found to correspond to the carious or tuberculous bone, from which it is separated by some bloody fluid; it will also be seen that the under edges of the erosion or perforation in the cartilage are separated to some extent from the subjacent bone, from which they readily peel off, and that they are bevelled off towards the aperture. 3d. That cartilage is susceptible of primary change of the nature of inflam- mation or ulceration, induced by the action of its own vessels, is the opinion of Brodie, Mayo, and Liston, all of whom have observed true vascularization of cartilage. This condition, however, is extremely rare, and is certainly not one of the more common forms of joint-disease, seldom occurring except in the more chronic stages of arthritis. These, however, are not the sole changes that take place in cartilage in arthritis; the observations of Goodsir, of Rainey, and of Redfern, all point to the fact that cartilage, like other extravascular tissues, is subject to other trans- formations, independent of the prolongation of vessels into it. The changes that ensue are, according to Redfern, of the following kind:—The cartilage- cells enlarge, become rounded, and granular-looking, and instead of containing two or three nuclei, a considerable number are enclosed in the cell-wall; even- tually these corpuscles break up and are disintegrated. The matrix of the car- tilage now softens, and according to Redfern, splits up into fibres or bands which become nucleated. A species of fatty degeneration also, as pointed out by Rainey, takes place, and helps to soften and break down the structure of the cartilage. In the more advanced stages of disease of cartilage, we find masses of porcellanous deposit attached to the ends of the bones in plates and layers, taking the place of the eroded cartilage. In other cases, again, a soft, pulpy, and vascular fibro-plastic deposit of a greyish, ashy, or reddish-brown color, with whitish streaks of a firmer material running through it in various directions, takes the place of the cartilage that has been removed, or that has undergone fibro-cellular degeneration. On ex- amination under the microscope, this will be found to be composed of plastic material, with cartilage-corpuscles intermixed, and with the subjacent bone in a state of disintegration and softening. This condition of joints I believe to be analogous to the "pulpy degeneration of the synovial membrane" of Brodie. It would appear, from the microscopical examinations that I have made of this PATHOLOGY AND CAUSES OF ARTHRITIS. 613 material, in various cases after the removal of joints, to which my attention was first directed by Dr. Quain, as occurring in a patient of his, whose elbow-joint I excised, that it is either fibro-cellular degeneration of the cartilage, or an imper- fect attempt at repair set up in the articulation, after the removal of the carti- lage by previous disintegration and disease. On making a vertical section of the surface of the diseased articulation in the case alluded to, it was found that the pulpy and villous substance covered the bone to the thickness of a line and more in some parts. The bone was found to have its cells filled with oil-glo- bules, but surrounded by tolerably healthy osseous tissue, showing the usual laminae and bone-corpuscles. Nearer the diseased surface the laminae and cor- puscles became less distinct, and, still nearer, the cells of the bony tissue appeared to be surrounded merely by a layer of fibrous texture, in which irre- gular particles of bone were observed. These particles, which were elongated, irregular in form, and rounded off at the angles, were very aptly compared, by Dr. Quain, to crystals in a state of solution. At the diseased surface, the place of the cartilage and synovial membrane was occupied by a fibrous texture abounding in cells, larger than pus-cells, nucleated and spherical, containing numerous granular particles. Irregular masses of cartilage, undergoing the same process of softening as the bony particles already mentioned, appeared in this fibrous texture. Tbe morbid appearances found in this case were so character- istic that they may be taken as the type of this peculiar morbid condition, which I have since repeatedly met with in other articulations besides the elbow, more particularly those of tbe fingers and the knee, and which always, I believe, con- stitutes an incurable form of disease. I have only met with this condition in instances in which the articular affection has been of very old standing, and fallen into a truly chronic state. When repair takes place in a joint, the cartilages of which have been eroded or destroyed, it is by the articular ends of the bones becoming connected, and the surface from which the cartilage has been removed filled up by fibro-cellular tissue, forming a kind of cicatricial material that leaves the joint permanently stiffened. In other cases again, porcellanous deposit takes the place of the eroded cartilage, and, in some instances, the exposed osseous surfaces may grow, or become soldered together, forming a permanent anchylosed and immovable state of the articulation. Under no circumstances does cartilage, when once destroyed, become regenerated. Causes.—In some instances, acute necrosis of the shaft of one of the long bones, as of the tibia, will run on to destructive action in the terminal articula- tions, the cartilages becoming undermined, softened, and perforated. It not unfrequently happens that the arthritic disease is the result of a morbid condi- tion of the articular ends of the long bones, or of those short bones that enter into the formation of the joint; this we especially see in diseases of the foot, of the elbow, of the knee, and hip; but it is a condition that, I believe, may occur in any joint. The bones usually become, in the first instance, the seat of tuber- culous infiltration; this runs into unhealthy suppuration, which gives rise to caries and limited necrosis (fig. 213, a); as the diseased action approaches the articular surface, the incrusting cartilage becomes loosened, detaches, and at the same time gradually disintegrates, and becomes perforated (fig. 213, b), nutrition in it being arrested or modified by the morbid state of the subjacent bone. When once the cartilage becomes affected, the whole of the interior of the joint speedily suppurates, and is destroyed. In other cases, inflammatory congestion, but without the formation of tuberculous matter, takes place in the articular ends, which become somewhat expanded, and then, without any suppuration occurring in the osseous structure, the cartilage gradually separates or peels off, and becomes softened and necrosed. This condition is often met with in dis- ease of the tarsal articulations. Diseased action is very seldom primarily set up in the ligaments of the joint, 614 DISEASES OF JOINTS. though these structures commonly become elongated, softened, and destroyed, as a consequence of other forms of articular disease. But though primary inflam- mation of the ligaments is so rare an affection as to have been denied by many, yet it certainly does occasionally occur. This is especially seen in the hip-joint, where the inflammatory affection may commence in the ligamentum teres; illus- trative of which there is a very beautiful model in the University College Museum. Inflammation may commence in the fibrous capsule of the joint: this we find more particularly to be the case when the affection is of a rheumatic character; in these cases inflammation, running into suppuration and slough of this struc- ture, will commonly spread to the internal parts. In some instances, this form of disease gives rise to the deposit of masses and layers of bone in the cellular structures outside the articulation. Arthritis commonly results from wounds of joints, or injuries, such as sprains and fractures occurring in their vicinity, more particularly in young people, and in those of a lymphatic constitution. It also occurs as a not unfrequent accom- paniment of pyemia (p. 381), and of some of the morbid conditions of the puer- peral state. The puerperal inflammation of joints is of a very destructive cha- racter, most generally speedily terminating in suppurative disorganization. One or several joints may be affected, and the knee is the one that I have seen most frequently and seriously involved. Puerperal arthritis probably depends upon a purulent infection of the blood as the result of uterine phlebitis. Arthritis not unfrequently occurs as a consequence of scarlatina, and I have especially seen the knee-joint affected in a destructive manner after this disease. In some forms of albuminuria there is also a great tendency to inflammation of the joints, and indeed I have so frequently seen that form of renal dropsy which follows scarlet fever accompanied by serious inflammation of some joint, as almost to look upon one condition as the sequence of the other. The symptoms of arthritis that are most marked are the pain, heat, swelling, and peculiar position of the joint. The pain is often severe, tensive, and throb- bing ; so acute is it sometimes that the patient screams with agony, he cannot bear the bed to be touched, the room to be shaken, or the slightest movement communicated to the limb : any attempt at examination of the joint in such cases being attended with insupportable agony. There are usually nocturnal exacer- bations, and the pain is commonly referred with especial severity to one particular spot in the joint; thus it is generally felt at the inner or under side of the knee- joint, and at the outer aspect of the hip. The heat of the diseased joint is considerable, and is often accompanied with more or less superficial redness. The swelling is uniform, involving the whole of the articulation, and not pro- jecting at certain parts of it, as when the synovial membrane alone is affected; it is generally not very considerable, and has a soft and doughy, rather than a fluctuating, feel. As the disease advances, however, the swelling generally increases suddenly, and to a considerable extent, either in consequence of the irritation of the synovial membrane, or of the accumulation of pus within or around the joint. In many cases the synovial membrane gives way, and the pus from the interior of the joint becomes widely diffused through the muscular interspaces of the limb, forming enormous abscesses and long sinuous tracts. The position of the affected limb is peculiar, and that attitude is insensibly adopted in which the patient will have the greatest amount of ease; thus the knee is semi-flexed and turned outwards, the thigh is adducted, and the elbow is bent. Spasms or startings of the limb, often of a very sharp and painful character, come on at times, more particularly at night. The constitutional disturbance is very severe, and of an actively febrile type. As the disease progresses, suppuration takes place within the joint, which becomes hot and red, with a good deal of throbbing pain, and at last fluctuation is perceived where the coverings are thinned. In some cases the suppuration PATHOLOGY AND CAUSES OF ARTHRITIS. 615 occurs with very great rapidity, and luxation of the head of the bone takes place. In other cases an abscess forms external to the articulation, and extensive purulent collections become diffused through the limb. As the joint becomes loosened by the destruction of its ligaments, the bones become mobile, and grate against one another where the incrusting cartilage has been removed, thus givin°- rise to very severe suffering. The cartilages may however in some cases be very extensively destroyed, and yet no grating take place; this is owing either to the destructive action being limited to the edge of the incrusting cartilage, the opposing surfaces being sound, or else to the interior of the articulation being filled up with plastic matter after the removal of the cartilages. But though abscess, either within the joint or external to it, usually forms when the bones grate and the cartilage disintegrates, yet it occasionally happens that these con- ditions may take place — those symptoms that are indicative of the erosion of the cartilage, such as painful startings of the limb, grating, and preternatural mobility of the joint, — and yet no abscess forms; all the symptoms subsiding under proper treatment, and the joint recovering, though perhaps with a certain degree of anchylosis. If suppuration take place, the constitutional disturbance usually partakes of the irritative type, the patient suffering severe pain, and being worn out by want of rest. Hectic may occur and death from exhaustion and irritation, unless the diseased part be removed; in other cases it falls into a state of chronic thickening, with perhaps fistulous openings leading down to the diseased structures, and in some of the more favorable instances the patient may recover, with a permanently rigid joint. Abscess may form external to, but close upon, the capsule of a joint, and closely simulate disease of the articulation. In these cases the absence of serious constitutional disturbance, the irregularity of the swelling, greater on one side than the other, the absence of all rigidity about the joint, and of other severe local symptoms, such as pain, starting, looseness, or grating, will enable the surgeon to effect a correct diagnosis. In the treatment of acute arthritis, perfect rest of the articulation is of the first moment. Unless this is secured no after-treatment can be of any avail. The limb should be comfortably supported on pillows, or laid upon a well-made and softly-padded leather-splint; at the same time blood should be freely taken away by cupping or leeching the affected part, and this local depletion must be followed by assiduous fomentations. In the acute stage of the disease the internal remedy from which the most essential service may be derived is the calomel and opium pill (gr. ij. and gr. ^) every fourth or sixth hour, at the same time that a strict antiphlogistic regimen is persevered in. After the violence of the symp- toms has been subdued, the joint may be repeatedly blistered; but in many instances most benefit will be derived by the application of the actual cautery. This agent, when properly applied, yields much more certain and successful results than any other form of counter-irritation with which I am acquainted. The patient having been anaesthetized, a cauterizing iron heated to a black-red heat should be rapidly drawn over the diseased articulation in a series of parallel lines, across which an equal number of cross bars are again drawn so as to char but not destroy the true skin. A good deal of inflammatory action is thus set up, followed by slight suppuration. When this has subsided, the application of the hot iron may, if necessary, be repeated; in this way the deep gnawing pain will usually be readily removed, and suppuration of the joint may be averted. For counter-irritants to be of any use, they must be employed before suppuration has set in; I believe that it is only torturing the patient unnecessarily to have recourse to these agents when once pus has formed in the articulation. In order that full benefit should be derived from this plan of treatment it must be perse- vered in steadily for a considerable length of time, and should be conjoined with a moderately antiphlogistic and alterative treatment. With this view, the bichloride of mercury in doses of from £ to T\j of a grain may be advantageously 616 DISEASES OF JOINTS. given with the compound decoction of sarsaparilla, or, if there be much debility, with the compound tincture of bark, nourishment, and even stimulants being conjoined with it, in proportion to the advance of the debility. When suppura- tion has taken place in this joint, more particularly if the skin covering it be reddened at any one part, the abscess should be freely opened. In some cases, even when abscess has formed, the joint being perfectly loose and grating, by perseverance in the above plan of treatment, both local and con- stitutional, a good and useful limb may be left; and although there be mobility and grating, provided there be no sign of abscess, the surgeon should never despair of obtaining a satisfactory result. The practice of making free incisions into a suppurating joint, as advocated by Mr. Gay, is a great improvement on the former method of merely puncturing it. If a small aperture only is made, air gets admixed with the pus, which becomes offensive and irritating, and being unable to escape freely, sinks to the bottom of the articulation with debris of the disintegrated cartilages, &c, giving rise not only to much local mischief, but to proportionate constitutional disturbance. By freely laying the joint open, all this is prevented; exit is given to the pus through one or two incisions that extend the whole length of the articulation; no constitutional disturbance can occur from pent-up and putrid matter, and the joint has a better chance of healthily granulating. After the formation of abscess the prognosis is more unfavorable, when large joints such as the knee or hip are affected; or, when those are implicated which are important to life, such as the articulations of the vertebrae; so like- wise, when the articular ends of the long bones are affected it is seldom that the joint can recover itself, as we have caries or necrosis complicating its dis- ease and keeping it up. When the articulation is very sinuous as in the carpus, or when a number of small joints communicate with one another, if not directly by synovial membrane, at all events indirectly through the medium of ligament and of fibrous tissue, as in the tarsus, a cure can scarely be anticipated. In all these cases, hectic and great constitutional irritation usually come on; or the joint becoming useless or cumbersome, its removal must be practised either by excision or amputation. The result will at last in a great measure depend upon the state of the bones that enter into the conformation of the joint. If these be sound, or not primarily affected, and the patient's constitution has got over the effect of the occurrence of suppuration in the joint, anchylosis more or less complete may be confidently looked for. But if the articular ends of the bones be primarily or deeply implicated, then excision or amputation will be the only alleviation. When an inflamed joint appears to be disposed to undergo a cure, its repair by anchylosis must be facilitated by keeping it in a proper position, such as will be most useful to the patient in after-life; the straight one for the knee and hip, and the semiflexed for the elbow. At the same time it may be useful to strap the joint firmly in the proper position in the way recommended by the late Mr. Scott, when it is the knee that is affected, or when the hip or elbow are implicated, fixing it well by means of starch bandages. Scott's plan of treatment consists in spreading on pieces of lint, the strong mercurial oint- ment, to every ounce of which 3J of camphor has been added; strips of soap- plaster spread upon leather are then cut of a proper length and breadth, and the joint firmly and accurately strapped up, the limb having previously been bandaged as high as the joint that is strapped. This dressing may be left on for a week or two until it loosens or gives rise to irritation; over the whole a starch bandage may be applied. In many cases, I have found it advantageous to strap up the joint with a plaster composed of equal parts of the emplast. ammoniaci cum hydrargyro and the emplast. saponis or belladonna?. These applications not only fix the joint and promote the absorption of the plastic STRUMOUS DISEASE OF JOINTS. 617 matter that is deposited around it, but by acting as gentle counter-irritants remove the remains of the inflammation that may be going on within it. STRUMOUS DISEASE OF JOINTS. By "white-swelling" is meant a very chronic form of arthritis occurring in scrofulous subjects. These diseases present peculiar characters; the affected joint is enlarged and rounded, the bony prominences being effaced by a uniform, doughy, semi-elastic, or pulpy swelling, occupying the interstices of the articu- lation. The integuments covering it preserve their white color, and there is usually but little pain felt except in moving the limb, and the position is always that in which the patient has most ease, the joint being generally semiflexed. There is a degree of stiffness and rigidity in the joint, and in consequence of the wasting of the limb from disuse, the affected articulation appears more swollen than it really is. This condition has not in many cases any definite starting-point, but appears slowly to supervene upon some slight injury, as a twist, or blow, or strain ; at other times it commences with a subacute synovitis, assuming its peculiar characters by occurring in a strumous constitution, and is especially liable to happen in children and females. The general health does not appear at first to suffer much, but as the disease advances symptoms of irritation and hectic declare themselves. This affection is always characterized by a special tendency to run on to suppuration. This tendency may be checked by proper treatment, but in the great majority of cases it at last passes into this condition. The joint suffers from exacerbations of intercurrent attacks of inflammation, the limb swells and becomes cedematous, and abscess finally forms in and around the joint; often around, before it takes place within. When this is opened, the constitutional symptoms become more severe, hectic speedily sets in, and strumous deposit takes place in other organs, such as the lungs, which at last carries off the patient. In this affection the tissues immediately external to the joint, as the fibrous capsule and the investing cellular membrane, are always much thickened and infiltrated with fatty and plastic matter; this gelatinous infiltration having a great tendency to run into unhealthy suppuration greatly adds to the mischief that ensues. In the interior of the joint we find much the same kind of changes that have been described as characterizing acute arthritis; the carti- lages have lost their polish, their elasticity, and their firm hard section, being softened, eroded, and disintegrated; the synovial membrane is removed in parts, and is here and there vascularized; in others it is replaced together with the cartilages, either by large quantities of the semi-transparent gelatinous- looking fatty deposit, or by the pulpy grey or brownish fibro-cellular material that is met with in arthritis. The ligaments are inflamed, softened, and destroyed, being converted into somewhat similar materials; and the interior of the joint is filled with a purulent-looking synovial fluid, thin and yellow, usually containing a large quantity of fatty matter. The bones undergo important changes in this disease, the articular ends becoming expanded and enlarged; and though this was denied by Crowther, Russell, and others, it is affirmed by more modern surgeons, and I have had repeated opportunities of determining the fact. In all the cases that I have examined the osseous tissue has under- gone important changes, the compact structure becomes thin and expanded, and the cells of the cancellated, filled with a bloody and fatty serous fluid. It is softened, often cutting readily with the knife, and owing to the deposit of fat presents a more homogeneous section than healthy bone. In many cases, tu- berculous matter is deposited in it. From this it would appear that the princi- pal changes that take place in a joint affected with white swelling consist in a 618 DISEASES OF JOINTS. kind of fatty degeneration of the tissues that enter into the formation of the articulation, associated with an unhealthy strumous inflammation of the parts, and the consequent deposition of considerable quantities of semi-transparent and lowly-organized plastic matter which, in its turn, has a tendency to undergo the same structural change, or to run into unhealthy suppuration. In the treatment of white swelling, we must bear in mind that we have to manage a truly scrofulous inflammation and its effects. Our first object should be to prevent, if possible, the occurrence of suppuration. In the early stage, when the affection has come on insidiously, without any very active symptoms, we must trust to general anti-strumous treatment, to the influence of diet, of sea-air, and the administration of alteratives, cod-liver oil, and iodine. In the local treatment, rest, with perfect immobility of the articulation, is the most important element, without which all the rest is futile. The limb should be put into such a position as is not only most easy to the patient, but that would leave the most useful member in the event of a stiff joint resulting. If the symptoms are of rather an acutely inflammatory kind, leeches may be applied; these, however, must be used as sparingly as possible, being confined either to the earlier stages of the disease, or to the subdual of any more active intercur- rent inflammation. Rest is best secured by leather or gutta-percha splints in the earlier stages, and at a later period, by the application of the starch bandage to the limb. This kind of application will be found to give the most efficient support, and will keep the whole of the limb perfectly motionless, so that the patient can take open air exercise, and walk with the aid of crutches, without the risk of injuring the diseased joint. In this respect, the starch bandage presents great advantages over the short leather splints generally used. It may readily be cut open opposite the diseased joint, so as to admit of the application of proper dressings to it. The actual cautery is extremely beneficial in these cases applied as directed (p. 615), or caustic issues may be put in, at a little distance from the articulation, so tbat there may be no risk of the inflammatory action penetrating to it. After all inflammation has, in this way, been removed, and nothing but thick- ening and stiffness of the joint are left, measures must be adopted for removing these conditions, and restoring the flexibility of the articulation by frictions with somewhat stimulating and counter-irritant embrocations, and eventually its strength, by douches of sea-water. The swelling and puffiness that are left, together with the debility dependent on relaxation of the ligaments, are perhaps best remedied by the use of Scott's strapping; but pressure should not be ap- plied so long as there is evidence of active inflammation going on in the articu- lation, which it would certainly increase. If abscess forms, this must be freely opened by an incision of a proper length, the joint poulticed, and the patient's general health attended to, so as to pro- mote the evolution of granulations, and the prevention of hectic. In these cases, if the limb can be preserved, its after-utility, and the patient's comfort, will mainly depend upon the position in which it is allowed to anchylose ANCHYLOSIS, OR STIFF JOINT. Anchylosis is invariably the result of the destruction of a joint by chronic inflammation, being the only mode in which nature can effect its repair, and consists in tbe more or less complete consolidation of the parts around and within the articulation. It is of two kinds: the incomplete, or fibro-cellular, and the complete, or osseous. In the incomplete, or fibro-cellular anchylosis, the stiffness of the joint may be dependent on thickening and induration of its fibrous capsule, or on the formation of fibroid bands as the result of inflamma- tion within the joint, or in consequence of the cartilages and synovial mem- ANCHYLOSIS. 619 brane being in part or wholly removed, and their place supplied by a fibroid or fibro-cellular tissue, by which the articular ends are tied together. Fig. 221. It may also be materially increased by the tonic contraction of the muscles around the joint. The complete or osseous anchylosis is of two kinds : in one, all the soft parts within the joint are destroyed, and the osseous surfaces have coalesced, or are fused together by direct bony union. This is most com- monly seen in the hip, knee, and elbow (fig. 221). In the other, there has been fibro-cellular deposit, or degeneration within the joint, and the bones, united partly by this, are also tied together by arches or bridges of osseous matter, thrown out external to the articulation, and stretching across from one side to the other. It has been supposed that these masses proceed from the ossification of the ligaments, or even the muscles; but, from the inequality of their appearance, it is evident that they are new and accidental formations. In the incomplete anchylosis there is always some degree of mobility, however slight, and, indeed, perhaps only perceptible on deep and close examination. In the complete form of stiff joint, the articulation is perfectly rigid and immovable. It not unfre- quently happens, in old standing cases of diseased joint, that more or less com- plete anchylosis is taking place at one part of the articulation, whilst caries or necrosis of the bones is going on at others. Under such circumstances, exci- sion or amputation will, probably, be the course to be pursued. The treatment of anchylosis is, in the first instance, of a precautionary nature, —that is to say, that when the surgeon finds that the establishment of anchy- losis is, as it were, the natural means of cure adopted by nature in a deeply- diseased joint, his efforts should be directed to seeing that the joint becomes anchylosed in such a position as will leave the most useful limb to the patient:—- thus, if it be the hip or knee, that the anchylosed joint be in the straight posi- tion ; whilst if it be the elbow, that it be placed at a right angle. When once the anchylosis has occurred, the treatment to be adopted will depend partly on the degree of stiffness, whether it be fibrous or osseous, and partly on the object to be attained, whether this be merely the restoration of mobility in a part anchylosed in a good position, or the remedying of the de- formity occasioned by faulty anchylosis. 1st. In attempting to restore the mobility of a joint anchylosed in a good position, as of a straight but stiff knee, the surgeon may usually succeed if the anchylosis be only of a fibrous character, (when some degree of movement will always be perceptible in the part,) by the employment of passive motion, frictions, and douches, more particularly with warm salt water or the mineral sulphureous springs. In the more obstinate cases, and where the immobility appears to depend, in some degree, at least, on fibrous bands stretching across the limb, an attempt might be made to divide these subcutaneously. _ In doing this no mischief can result, for the synovial structure of the joint having been destroyed, no dangerous amount of inflammation can be set up in it. . . .. „ 2d. When fibrous anchylosis has taken place in a faulty position, — it, for instance, the knee be bent, or the elbow straight, the first thing to be done is to place the limb in such a position that it will be useful to the patient. This may most readily be done by chloroforming the patient, and then forcibly 620 ON EXCISION OF JOINTS AND BONES. flexing or extending the limb, as the case may require, when with loud snaps and cracks it will usually come into proper position. Should any of the tendons in the vicinity of the joint appear to be particularly tense, they may be divided subcutaneously. The inflammatory action that follows this forcible extension or flexion of the limb is usually but of a very trivial character; an evaporating lotion and rest will speedily subdue it. Indeed, it is surprising what an amount of violence may be inflicted on an anchylosed joint without any bad conse- quences ensuing. After the limb has been restored to its proper position, passive motion and frictions may tend to increase its mobility. 3d. When osseous anchylosis has taken place, and the position of the limb is a good one, it will generally be wiser for the surgeon not to interfere; except in the case of the elbow-joint, which, under these circumstances, may be excised with advantage, so as to substitute a movable for an immovable articulation. If the position be a faulty one, the osseous union may be divided, or a wedge- shaped piece of the bones may be taken out, and the position of the limb thus rectified. 4th. Amputation may be required in cases of faulty anchylosis with so much atrophy of the limb as to render this useless, or in cases in which there is necrosed or carious bone co-existing with anchylosis and rigid atrophy of the muscles of the limb. CHAPTER XLIV. ON EXCISION OF JOINTS AND BONES. To the surgeons of this country is undoubtedly due the merit of originating and carrying out the practice of excising diseased joints and bones with the view of saving a limb, by the removal of those morbid structures that would otherwise have necessitated amputation. Although the older surgeons, dread- ing amputation, on account of the difficulty they experienced in arresting the hemorrhage from a stump, had recourse to various gouging, scooping, and scraping operations in cases of diseased bone, yet they never attempted the excision of a joint, or indeed the resection of a whole bone. The articulated ends of bones were first excised in a compound dislocation of the elbow as far back as 1758, by Wainman of Shripton, and afterwards by White, Bent, and Orred in cases of compound dislocation of the humerus. In 1762, Filkin of Northwich excised the knee for disease, and in 1775, Justamond cut out the olecranon and two inches of the ulna for diseased elbow-joint. The first distinct publication on the subject was by Mr. Park, in 1782, the object of which was to show that in some of those affections of the knee and elbow for which amputation had hitherto been considered indispensable, surgery possessed another resource " in the total extirpation of the articulation, or the entire removal of all the bones which form the joints, with as much as possible of the capsular ligament." In the same year, Moreau excised the ankle-joint, and some years subsequently, the head of the humerus and the knee-joint. The new practice made few converts, however, and in 1805, Mr. Park, in another publication expresses his mortification that it had not met with the success in this country that it deserved, and that if it had not been for the Moreaus in France it would have fallen into complete oblivion. Although these operations continued to be occasionally performed, it was not until a quarter of a century later that they were again prominently brought before the profession, and the ON EXCISION OF JOINTS AND BONES. 621 second revival was due to the Edinburgh surgeons, chiefly to Liston and to Syme. Since then, they have continued to gain in favor, and now constitute that department of surgery which has been termed the conservative, or more correctly the preservative. Before proceeding to discuss the different resections in detail, we must endeavor to lay down some general rules for their performance in those cases in which they are alone admissible. The excision of an articulation may be practised for the following reasons: — 1st. As a substitute for amputation in cases in which the joint is so exten- sively diseased, that the patient will be worn out by the discharge or pain, unless it is removed. Here a useful limb may be secured by the sacrifice of the diseased part. 2d. In some cases of articular disease in which amputation would not be justifiable, excision may be done in order to hasten the cure, and thus to save years of suffering to the patient. 3d. Excision may be done in cases in which amputation is not practicable : as in disease of the hip-joint or temporo-maxillary articulation. 4th. As a substitute for other and less efficient treatment, in order to restore the utility of a limb or joint; as in osseous anchylosis of the elbow, or faulty anchylosis of the knee. 5th. Excision may be required in bad compound dislocations and fractures into joints, especially in gunshot injuries; as of the head of the humerus and elbow. . As a general rule, such resections are more required for diseases of the articular ends of bones than for simple disorganization of a joint. If only the soft structures of a joint are involved, it usually happens that without the necessity of resection a useful limb will result — if in the upper extremity with fair mobility of the articulation — if in the lower, with more or less complete anchylosis, not perfect mobility perhaps, but yet sufficient for a fair basis of support. But when the constitutiou is very strumous, or the bones very extensively affected, we can scarcely look for recovery of the limb to such an extent as to become useful to the patient. For resection to succeed, the following conditions appear to me to be DGCGSSRl'V " —— 1st. That the disease be not too extensive, so that its removal would entail such an amount of mutilation of the limb, as to render it less useful to the patient than an artificial member would be. This is especially important in the lower extremity. If the bones are so extensively affected as to require to be shortened by a considerable extent —for several inches —a limb would be left, that instead of serving as a proper basis of support to the patient, would only be an incumbrance. In the upper extremity, length and strength are of less consequence than in the lower; the preservation of the hand is the chief thing to aim at, and if this be effected, the bones may be encroached on to a greater extent than is proper in the lower limb. 2d. The disease for which resection is practised should be allowed to become chronic before any operation is undertaken: for this there are two reasons. First, because in the acute stage of disorganization of a joint, it is not always possible to say, however unpromising the case may appear, whether anchylosis may not result, so that as useful a limb would be left as could be obtained by resection. And, secondly, if the joint be excised whilst acute and active disease is going on, inflammation and diffuse suppuration of the medullary canal is apt to set in_a condition very apt to be followed by phlebitis and pyemia. In the only fatal instances of resection of the elbow-joint that I have witnessed, death resulted from this cause, the operation having been performed whilst the articu- lar affection was acute. 3d. The soft parts about the joint must be in a sufficiently healthy state. 622 ON EXCISION OF JOINTS AND BONES. There are two morbid conditions connected with the soft parts that may inter- fere with the success of resection. First, they may be so thinned and per- meated by sinuses, and so adherent to the bones, that an insufficient covering would be left. Or, secondly, the long-continued existence of strumous disease in joints and bones may give rise to a great deposit of lowly-organized plastic matter around the articulation. This material becomes insusceptible of healthy organization, and slowly suppurates. Sinuses form in it, the integuments cover- ing it become blue and doughy, and the soft parts around the seat of operation fall into a state of strumous disorganization that prevents alike the formation of a false joint, of osseous anchylosis, or of the healing of the wound, and thus leads inevitably to the ultimate amputation of the limb. 4th. The state of the patient's constitution must necessarily influence the surgeon materially in his determination whether to resect or to amputate. If the constitution be tolerably sound, or if the general health has given way, pro- vided that it has done so as the simple consequence of pain, irritation, and continued discharge, resection will have a fair prospect of success. But if the patient be very highly strumous, or decidedly phthisical, there will be little prospect of his being able to bear up through the long convalescence that follows resection. A^slight degree of pulmonary disease, however, that appears to be rather the result of the long-continued irritation of the local affection than of any constitutional taint, need not be a bar to these operations. In such cases, I have several times had occasion to observe that the general health improved rapidly after the removal of the local disease. 5th. The extremes of life are unfavorable to resections. In very early child- hood, these operations are seldom necessary, the natural processes usually suffi- cing, with very little assistance, in eliminating diseased bone, and the disorgan- ized joints admitting readily enough of anchylosis. If the disease is too severe for this, it will usually be found to be associated with so strumous a constitution as to interfere with healthy reparative action of any kind. At advanced periods of life, destructive joint disease is not very common, and when it does happen, it is generally not in constitutions fitted to stand up against the prolonged drain consequent on these operations. It is at the early adult age that the diseases most frequently occur that render resections necessary, and at which these ope- rations are best borne. When a bone, as the os calcis, has been entirely removed, it is never of course regenerated, but its place is occupied by a firm fibrous cicatrix. When partial excision of a bone is practised, the result varies according to the tissue that is removed. If a portion of the compact tissue is cut away, callus is thrown out. If it is the cancellous structure that is scooped out, the cavity left is filled up by a dense fibrous mass, which may eventually ossify. When a joint has been excised, cither osseous or ligamentous anchylosis may take place, and the surgeon should endeavor to secure osseous union in some, fibrous in other cases. Thus, when the knee has been excised, as a sound and firm limb is desirable, osseous anchylosis should if possible be brought about; whilst in the upper extremity, where mobility is of more use than strength, ligamentous union is most desirable. In these cases, the ends of the bones become rounded, and are united by a dense mass of fibrous tissue which enve- lopes them, and to which the insertions of those muscles that are naturally connected with the articular ends that have been removed, become attached. The instruments required for resection are of a somewhat varied character; strong scalpels and bistouries, straight and sharp-pointed. In addition to these, I have found a strong-backed, probe-pointed bistoury, with a limited cutting edge, of great utility in clearing the bones. The pliers should be of various sizes and shapes (figs. 205 to 208), and gouges will be found useful for scooping out suspicious patches on the cut osseous surfaces. For ordinary purposes, a small amputating saw will, I think, be found the most convenient instrument for EXCISION OF THE SHOULDER. 623 dividing the bones, but in some cases a narrow keyhole saw, or that introduced by Mr. Butcher (fig. 222), will answer best. The last instrument is especially Fig. 222. useful when it is intended to cut the bone obliquely, or when the space is limited; for, as the blade is narrow and its angle can be changed at pleasure, any required direction can be communicated to the cut. The chain-saw is perhaps not used so frequently as it might be. With regard to the steps of the operation, they must of course vary with the different resections, but there are some general rules that may be laid down as applicable to all cases. 1st. The incisions through the soft parts should be sufficiently free to expose thoroughly the bones to be removed. By making them, as far as practicable, parallel to tendons, blood-vessels, and nerves, parts of importance may readily be avoided. 2d. As little of the bone as possible should be removed. It is seldom that the shaft need be encroached upon, and care should always be taken to avoid opening the medullary canal. It is of importance, also, not to mistake rough- ened deposits of new for caries or necrosis of the old bone. 3d. The gouge may be applied to any carious or tuberculous cavities, or patches, that appear upon the surface of the freshly-cut bone, and, in this way, shortening of the bone by the saw may be materially avoided. 4th. Skin, however redundant, should seldom if ever be cut away. The flaps, at first too large, soon shrink down to a proper size, and if trimmed are very apt to become too scanty. 5th. After the operation, light dressings only should be used. As healing always takes place by granulation, no accurate closing of the wound is neces- sary, but it is sufficient to lay the limb on a pillow, or well padded splint, and to apply water-dressing. When it begins to granulate, more accurate attention to position is required. 6th. The constitutional after-treatment should be of a nourishing or stimu- lating character. As there will be a great drain on the system, and a prolonged confinement to bed, the strength must be kept up under it by good diet. These operations are always of a serious character, in many cases fully as much, or even more so, than the amputation of a corresponding part, owing to the large wound that is often inflicted, in the more extensive division of the bones,—to the necessity of making the incisions in the midst of diseased or injured struc- tures— and to the more prolonged character of the after-treatment. Hence it is of especial importance that the general health should be carefully maintained after these operations. Excision of the shoulder-joint is not so commonly required as that of many other articulations; disease of this joint not being of very frequent occurrence, and, when it happens, often terminating in false anchylosis, without suppu- ration taking place. When abscess and necrosed bone are met with about the 624 ON EXCISION OF JOINTS AND BONES. shoulder, it will frequently be found that the coracoid or acromion processes are at fault rather than the joint itself, and extraction of sequestra formed there may prevent excision of the articu- lation. When practised, it has usually been required for strumous disease, especially occurring in young people. It has not unfrequently, of late years, been performed, and with very considerable success, for gunshot injury of the head of this bone. M. Baudens relates 14 cases in which it has been practised for these injuries during the Crimean campaign, and of which only 1 proved fatal. The articula- tion may most readily be ex- posed by making a semi-lunar flap about three inches in length, commencing at the pos- terior part of the acromion, cut- ting across the line of insertion of the deltoid, and carried up to the inner side of the coracoid process. Or the surgeon may adopt T ~T or l~l shaped inci- sions. I think, however, that the elliptical, or \J shaped is preferable, or less muscular fibre is sacrificed by it. By a few touches of the scalpel a large flap composed of the deltoid muscle may thus be raised, and the diseased articula- tion fully exposed. As the capsule and the ligaments are destroyed by the morbid action that has taken place in them, the head of the bone may readily be turned out of the glenoid cavity; and being freed by a few touches of the knife, and isolated by passing a spatula behind it, may be removed with a narrow saw (fig. 224). In doing this, the shaft of the humerus should be encroached upon as little as possible, not only that the bone may not be shortened more than is necessary, but in order that wound of the circumflex arteries may be prevented, which will certainly happen if the incision be carried too low down. After the removal of the head of the bone, the glenoid cavity must be examined; if this be carious, it may be removed most conveniently by means of gouge- forceps and the gouge, care being taken that all diseased bone is thoroughly scooped away. After the operation, the flap must be laid down, and re- tained in position by two points of suture, and the arm well supported in a sling, the elbow especially being raised. The wound unites by granulation, and though the deltoid muscle does not recover its full utility, a very excellent limb and most useful fore-arm and hand are left to the patient, as may be seen by the accompanying drawing (fig. 224), taken from a lad whose shoulder-joint I removed some years ago. I last saw this boy about four years after the operation had been performed, and then found that the upper end of the humerus had been drawn up underneath and between the acro- mion and coracoid processes, where a false joint The arm was extremely useful, and the parts below the elbow well Fig. 224. had formed. EXCISION OF THE ELBOW JOINT. 625 developed. The upper arm was two and a half inches shorter than the other. The excision of this joint is not devoid of danger. Velpeau records 13 cases of death following it, and states that many more have occurred. The scapula has occasionally been excised in part, or in whole, for gunshot injury or disease. Most commonly these operations have been practised after the arm had been removed at the shoulder-joint, the state of the scapula requir- ing its ablation at a later period, an operation that I saw admirably performed about ten years ago by Mr. Fergusson. Occasionally, however, the scapula has been excised without previous amputatien of the arm. Thus Liston removed three-fourths of the bone for a vascular tumor springing from it. South excised the whole of the body of the scapula by sawing through its neck, and Syme has recently taken away the bone with its processes entire. Operations such as these are rarely required, and when called for can scarcely be performed in ac- cordance with any positive rule, the operator varying the extent and arrange- ment of his incisions according to the extent of the disease, the situation of sinuses, &c. In whatever way practised, there is one rule, however, that should be attended to, viz., that the axillary border of the bone should be the last to be interfered with, on account of the hemorrhage that may be expected from this situation. The Clavicle has been partially or wholly excised by Travers, Mott, and others. In caries or necrosis of this bone, portions of it may be gouged away or extracted without much difficulty; but when in consequence of the growth of tumors, the removal of the whole or greater part of the bone is required, the operation is one of the most hazardous in surgery, as a glance at the anatomy of the parts lying beneath the bone, and encroached upon by the morbid growth, will indicate. In Mott's case 40 ligatures were applied. The sternal end of the clavicle has been excised by Mr. Davie of Bungay in a case in which dislocation backwards had resulted from deformity of the spine, and the luxated end gradu- ally pressing upon the oesophagus, threatened the life of the patient. The bone was cut through by means of a Hey's saw about an inch from its sternal end, and the sterno-clavicular ligaments having been divided, the portion of bone was forcibly elevated, and at last extracted. Excision of the elbow-joint has been more frequently practised than that of any other of the articulations, and the result has upon the whole been far more satisfactory. This operation may be required, 1st, for a chronic disease of the joint; 2d, for osseous anchylosis; and 3d, for injury. In those cases in which it requires to be excised for disease, it will generally be found that after disease has existed for a considerable time in the joints, the limb will be useless, and the soft parts around it swollen, spongy, and perforated by fistulous openings. In other cases there will, however, be very little external evidence of mis- chief, merely one or two fistulous aper- tures leading down to the condyles and to the olecranon, the joint being permanently lexed and swollen, and the arm so useless that it cannot support the weight of the hand. On exposing the arti- culation, perhaps caries, with complete destruction, and with or without necro- sis of the articular ends, the loose pieces of dead bone lying in the cavity of the olecranon, or in one of the condyles, may be found. Most commonly the radius is the last bone that is affected, the ulna and opposite side of the humerus being generally first diseased. If osseous anchylosis have occurred, whether in the straight or bent position, excision of a portion of the consolidated bone may also advantageously be practised, as in these cases a useful and movable articulation may be substituted for one that is rigid and fixed. In cases of compound frao- 40 626 ON EXCISION OF JOINTS AND BONES. ture or dislocation of the elbow-joint, more or less complete resection of the protruding, and possibly splintered fragments, may be required. Fig. 226. Excision of the elbow-joint is a very successful operation. I have only lost one patient out of ten cases in which I have done this operation. The princi- pal danger after excision of the elbow-joint probably arises from diffuse suppu- ration of the humerus. I have seen this happen in two fatal cases; and in a third, in which the patient lost his life, it is probable that death, which was attributed to pneumonia, remotely occurred from the same cause. The elbow- joint may be excised in three ways: 1st. By an t— shaped incision (fig. 225); 2d. By the H incision; and 3d, By a single longitudinal incision (fig. 226). Of the two first, I prefer the h- shaped, as it leaves a better result, with less cicatrix, than the H incision. The patient having been laid prone, the perpendicular cut should be made parallel to, and a line or two to the outer side of the ulnar nerve; being com- menced at least two inches above the olecranon, and carried down to about the same distance below it. The transverse incision should then be made directly across the olecranon, to the outer side of the joint, and extended as far as the extremity of the outer condyle (fig. 225). The two triangular flaps thus made must be dissected up, the knife being carried close to the bones. Or the trans- verse incision may be dispensed with, and the bones readily exposed and turned out by the 3d method, that of the single perpendicular incision (fig. 226). This must be of sufficient length to allow of the sides being held well apart, and then it constitutes the simplest plan of excising the elbow that can well be devised. After the bones have been fairly exposed, they must be cleared to the inner side of the joint; in carrying the incisions in this direction, the edge of the knife should always be kept against the bones, and their sinuosities closely followed, so that the ulnar nerve being dissected out from behind the inner condyle, may escape injury. If the incisions are properly planned, and the knife kept in contact with the bone, the nerve ought not to be exposed during the operation, more particularly as it is usually imbedded in a quantity of plastic tissue. When the posterior part of the joint has been laid bare in this way, the knife should be carried round the tip of the olecranon, and this process then removed with cutting pliers. By forcibly bending the joint, pushing the forearm upwards, and lightly touching the ligaments with the point of the knife, the interior of the articulation will be fully exposed. If the whole of it is dis- eased, the surgeon must, of course, excise it completely; if it is only partially EXCISION OF THE WRIST. 627 affected, it is better also to practise complete excision than to limit the removal to those portions only that are implicated. By means of a small narrow saw, the articular end of the humerus is separated from the rest of the bone; the upper end of the ulna and head of the radius may either be removed in the same way, or by means of cutting pliers. There is never any necessity to place a spatula before the bones, as the parts of importance anterior to the joint could not easily be wounded, being completely protected by the brachialis anticus. Tne ulnar nerve will occasionally, however, be in some danger, and it must be guarded or drawn on one side by a bent copper spatula. In this operation it is of great consequence, so far as the after-utility of the arm is concerned, not to remove more of the bones than is absolutely necessary; the shaft of the humerus, for instance, should never be encroached upon, but it will be quite sufficient to limit the excision to the articular surface; should any carious por- tions of the bone extend beyond this, I think it is better to scoop them out with the gouge than to remove them in any other way. The excision of the ulna and radius should not be carried so low as to divide the insertions of the brachialis anticus and biceps. In some instances, no vessels require ligature, though there may be free general oozing; but most commonly one or two must be tied. In some cases, it is said, that the bleeding has proved extremely troublesome. This, however, I have never seen. After the operation, the limb should be laid upon pillows nearly in the extended position, so that the cut portions of bones are in close approximation with one another. If the excision has been practised through a single straight incision, there will be but little if any gaping of the wound, the flaps falling closely together. If any transverse cuts have been practised, the edges cannot so readily be brought into apposition. At the end of a week or ten days, when granulations have sprung up, it may be put in a slightly bent leather splint, and as the healing process goes on, this may gradually be flexed, until at last it is brought to a right angle. The fibrous union that takes place between the bones will be closer, and a more compact and useful false joint will form, than if the osseous surfaces be too widely separated in the first instance, and be allowed to unite by a lengthened ligamentous tissue. Until the con- traction of the cicatrix has fully taken place and the neighboring tissues are quite firm, the joint should be supported by one lateral leather splint, on the inner side of the arm. Much of the success in the result of excision of this, as of other joints, will depend upon the care and attention bestowed on the after- treatment of the case. The position of the parts and the relation of the bones to one another should be scrupulously attended to, bagging of matter prevented, and exuberant granulations repressed. At the same time the patient's strength must be kept up by constant attention to diet, fresh air, &c. In this way good ligamentous union will take place. In a case which I had once the Fig. 227. opportunity of examining, about six- teen months after the operation, it , was found on dissection that the . ends of the bones were rounded and ^ firmly united by a dense ligamentous structure. In this way a most excel- lent and useful limb will result with but little deformity, as may be seen by the accompanying cut (fig. 227), which was taken nearly two years after operation from a patient of mine. A coachman, whose elbow-joint I excised, was able to drive, to lift a pail of water, and to do all the duties of his employment nearly as well as if the arm had been left in its normal condition. Excision of the wrist is not an operation that has found much favor with sur- geons. Most commonly when the carpus is diseased the morbid action rapidly 628 ON EXCISION OF JOINTS AND BONES. extends with great constitutional irritation to all the small bones that enter into its formation, and although in some cases a few of these may have been success- fully taken away, yet methodical excision of the whole of the joint has not been followed by very satisfactory results, having either been attended by persistence of the disease in the soft parts, or followed by a stiff and useless hand and arm. A great objection to excision of the wrist consists in the superficial character of the articulation, and its close connection with the flexor and extensor tendons; hence, when the wound cicatrizes, consolidation of these and of their sheaths is apt to result, and loss of that utility of hand, the preservation of which should be the great object in the performance of the operation, is entailed. The operative procedure varies according to the amount of disease. When only a few of the carpal bones are diseased, they may readily enough be removed, through an extension of any fistulous openings that exist over them. But when the lower articular ends of the radius and ulna are implicated, a more formal operation is required; and one that is not unattended by some little difficulty, on account of the necessity of saving the extensor tendons of the fingers and thumb. Those tendons, however, that are inserted into the metacarpus, such as the supinators, and the radial and ulnar extensors, may be divided; for, as an- chylosis will, under the most favorable circumstances, result, their preservation can be no object. The surgeon has the choice of two modes of exposing the radio-carpal articu- lation. A horse-shoe flap, with its convexity downwards, may be made on the dorsal aspect of the joint, and then dissected up without dividing the extensor tendons of the fingers; the articulation is thus freely exposed; the carpal bones may be removed, and the lower ends of the radius and ulna clipped off. Or a longitudinal incision may be made on either side of the joint, the lower ends of the radius and ulna removed, and the carpal bones that are diseased, extracted. Of the two operations I prefer the former, as it gives more room; but even by it, the removal of the bones without cutting across the extensor tendsns is a troublesome procedure. In whatever way performed, excision of the wrist-joint is not a very satisfactory procedure, and in most of the cases in which it has been done, secondary amputation has been required; the wound not healing, or the hand being left in a useless state. Excision of the ulna or radius.—One or other of the bones of the forearm has occasionally been excised with advantage; leaving a sufficiently useful limb with good power in the hand. Dr. Carnochan, of New York, and Mr. Jones, have successfully excised the whole ulna. Dr. Butt of Virginia, has removed the whole radius.1 In a Fig. 228. case which was under my care about two years ago, I also re- sected successfully the whole radius with the exception of its articu- lar head, which was sound, and a useful arm, of which the an- nexed figure is a good representation, was left (fig. 228). These ope- rations do not require any specific rules for their performance; the bone is exposed by a long incision, and then carefully dissected out from the parts amongst which it lies. 1 [The excision performed by Dr. Butt was not that of the radius, as stated in the text, but a resection of the ulna. The report of the case is somewhat confused, and it seems as if only the lower three-fourths of the bone were removed. See Philadelphia Journal of the Medical and Physical Sciences, for 1825.] CONSERVATIVE SURGERY OF THE HAND. 629 Conservative surgery of the hand. — In the removal of diseased or injured portions of the hand, it is, as a general rule, of the greatest consequence to sacrifice as little as possible of the healthy or uninjured structures. In all ope- rations on the hand, indeed, we must have two great principles in view, — the preservation of the utility of the member, and the maintenance, so far as prac- ticable, of its symmetry. Utility is necessarily the primary consideration ; but if a part is not useful, it may, as in the case of the head of the middle metacarpal bone in amputation of the corresponding finger, be sacrificed for the purpose of preserving the symmetry of the maimed limb. The hand is the organ of pre- hension and of touch, and in all operations applied to it we should endeavor as far as practicable to maintain its efficiency in both these respects. It is also of importance to bear in mind that two great classes of actions can be carried out by the hand; those that require force, and those that require delicacy of manipu- lation rather than strength. By a surgical operation we may sometimes succeed in preserving one, though we are compelled to sacrifice the other, and in this respect, our procedure should be a good deal influenced by the occupation of the patient. Thus, by partial excision, we may leave a hand that would enable a clerk to hold his pen, but that would be almost useless to a laborer or black- smith. In looking at the hand in a surgical point of view, we may consider it as being composed of two constituents — the hand proper, and the thumb; the thumb being an accessory hand, an opponent to the rest of the member, through the medium of which the movements of ab- and adduction are chiefly performed, and without which the member is susceptible of a comparatively limited utility, being capable of little beyond flexion and extension. Hence the thumb is of equal importance to the rest of the hand, and the preservation of its three bones is as much to be considered as that of the remaining sixteen that enter into the conformation of the metacarpus and fingers. In all cases of injury or disease implicating the thumb, every effort ought to be made for its preservation. Even if it be left stiffened and incapable of flexion, it will be a most useful opponent to the rest of the hand. Should it be found necessary to shorten it, care must be taken that as little curtailment as possible be practised — a portion of a pha- lanx, or its metacarpal bone even, is of essential utility in giving strength and breadth of grasp to the hand. In cases of disease, a very useful member may be left by the removal of a portion or the whole of the ungual phalanx, of the metacarpo-phalangeal articulation, or even by the excision of the metacarpal bone, the phalanges being left behind. These various operations are easy of performance; an incision through the diseased and disorganized soft parts will expose the necrosed bone or carious joint, which must be removed by cutting- pliers or a narrow saw. When the thumb has been forced back or badly lacerated by powder-flask or gun-barrel explosions, it may often be saved by being replaced and maintained in position on a splint, with light water-dressing over it; and should amputation be required, it must be done in accordance with the rule just mentioned, viz., of saving as much as possible of the injured part. In the conservative surgery of the fingers, the preservation of flexion and extension in the part left, is the main thing to be aimed at; a rigid stump is always in the way. The preservation of these movements becomes more im- portant in proportion as the palm is approached. It is of more consequence that the proximal phalanx, which carries the rest with it, should be capable of beino- bent into the palm, than that the distal can be flexed on the second. If the proximal phalanx can be bent down, a very small degree of movement in the distal one will be sufficient to furnish pliability enough in the finger to make it a useful member; but if the proximal one is stiffened, no amount of mobility in the distal phalanx can make it useful. In preserving these movements it is necessary to be particularly careful of the 630 ON EXCISION OF JOINTS AND BONES. sheaths of the tendons. If they be in any way opened or injured, it will gene- rally be found either that the tendon sloughs, or that it becomes consolidated, and matted to its sheath in such a way that all movement is lost, or at least greatly impaired. The only phalanx that can be excised with advantage is the distal one. It often happens in the destructive disorganization that results from whitlow, that this necroses; when, instead of amputating the end of the finger, it maybe removed by an incision on its palmar aspect. Disease of the phalangeal articu- lations usually leads to amputation of the affected finger. The rules for per- forming these various operations have already been laid down at pp. 25-26, to which I must refer the reader. Resection of the metacarpal bone, either of the thumb or index finger, without the removal of the corresponding digit, is occasionally required, more particu- larly in cases of injury; and may readily be done by making a longitudinal incision over the dorsal aspect of the bone to be removed, carefully detaching it from surrounding parts by keeping the edge of the knife close against the bone, avoiding the tendons, and then, either disarticulating, or, what is prefer- able, cutting across the neck of the carpal end of the bone, turning it out, and separating it from any distal attachments it may retain. After the removal of the metacarpal bone of the index finger in this way, but very little deformity results. Conservative surgery of the lower extremity. — In all conservative operations that are practised on the lower extremity, it is of essential importance that a good basis of support, of sufficient length and stability, is left to the body. These operations differ thus in some important respects from those that are practised on the upper extremity. In the latter, the preservation of the hand, even though in a mutilated condition, is the thing that the surgeon aims at; and provided this be attained, it matters comparatively little how much the arm may be shortened or impaired in power. In the lower extremity, however, strength, length, and solidity are essential to the patient's comfort; and, unless these can be secured, his interests are better considered by the removal of the limb, and the adaptation of some artificial contrivance, than by his being left with a shortened, wasted, and crippled member, which is unequal to support the weight of the body. Resections of the Foot. — In looking at the division of the foot into its three great component parts — toes, metatarsus, and tarsus,—we shall perceive that firmness of gait is given by the foot resting on the heel behind, and the ball in front, formed by the projection of the broad line of the metatarso-phalangeal articulations, more particularly that of the great toe, — whilst elasticity is com- municated to the tread by the play of the toes and metatarsal bones. The elas- ticity of the foot may be lost without any very serious inconvenience to the patient; but the preservation of stability and firmness of gait are of essential importance; and, as these are secured by the heel, the ball of the great toe, and the breadth of the anterior part of the foot, these are the most important parts to preserve in all resections of this part of the body. The foot is frequently the seat of strumous disease; to this it is disposed by the alternations of temperature to which it is subjected, its liability to sprains and injuries, and by the cancellous and spongy structure of its bones, together with its extensive articulating surfaces. When affected by strumous inflamma- tion it becomes painful, the patient being unable to bear upon the toes or anterior ball of the foot. Swelling takes place of a uniform character, tender- ness at some point opposite the bones or articulations that are chiefly involved, and eventually abscess forms, leaving sinuses through which the probe passes down upon softened and carious bone. These evidences of disease are usually much marked about the dorsum and sides, the sole being often comparatively free from disease; an important point in reference to operation. CONSERVATIVE SURGERY OF THE FOOT. 631 In studying the conservative surgery of the foot, it must be borne in mind that at least six distinct and separate articulations exist between the different tarsal bones, and between these and the metatarsus; that any one of them may be distinctly and separately affected, and that, as they vary very greatly in size, complexity, and importance, the danger to the foot will differ much according to the articulation that is the seat of disease; it will also, as a general rule, be found that the prospect of successful excision of tarsal or metatarsal bones, will be much influenced according as the operation opens up large and complicated synovial surfaces common to many of the bones, or is confined to a synovial surface of more limited extent. The smaller synovial membranes, disease of which is seldom attended by serious risk to the whole foot, and which readily admits of the application of excision, usually with removal of the contiguous bones, are the following: — 1st, that between the metatarsal bone of the great toe and the internal cuneiform ; 2nd, that between the fourth and fifth metatarsal bones and the cuboid; 3rd, the calcaneo-cuboid; 4th, the posterior calcaneo- astragaloid. The remaining two synovial membranes are of large size and com- plex in their arrangements, dipping, as they do, deeply into the foot, and corre- sponding to the articular surfaces of many bones, their disease is always of serious, and often fatal importance to the preservation of the member. They are, 1st, that membrane which extends between the astragalus and scaphoid into the anterior calcaneo-astragaloid articulation, and 2nd, the large and com- plex anterior tarsal synovial membrane, which comes into relation with the scaphoid, the three cuneiform bones, the cuboid, and the second and third metatarsal bones. Strumous disease may commence either in the bones, or in the articulations of the foot. The bones that are most frequently the seat of primary disease are, the calcaneum, the astragalus, the scaphoid, the cuboid, and the metatarsal bone of the great toe. When limited to one or two of these bones, excision is usually practicable; but when the morbid action extends, through the influence of the connecting articulations, to other bones of the tarsus or metatarsus, partial amputation will be required. Primary disease of the articulations of the foot is a frequent cause of opera- tion, and the particular operation required will in a great measure depend upon the extent of the implication of the synovial membranes of the foot. When the calcaneo-astragaloid or the calcaneo-cuboid articulations are alone affected, resection of the bones and joints implicated will often be attended by very satisfactory results; but when the large anterior tarsal synovial membrane is in a state of chronic disease, either as the result of primary morbid action set up in it, or secondarily to diseases of the scaphoid, the cuneiform, or of either of the metatarsal bones connected with it, then resection is scarcely admissible, and Chopart's amputation offers the best means of relief. The inflammation of the large and complicated anterior tarsal synovial membrane commonly commences in disease of the scaphoid. It may usually readily enough be recognized in its earlier stages by the pain and swelling that take place across the line of articu- lation between the scaphoid and cuneiform bones, the pain being greatly in- creased by bending the foot down, and extending across the whole breadth of the foot. For, although usually most severe at the inner side, which is the first affected, yet the external section of this complicated articulation, that between the external cuneiform and the cuboid, becoming involved, causes suffering to be experienced on the outer side of the foot as well. In the more advanced stages of this particular disease, the foot assumes a remarkable bulbous or clubbed appearance; the symmetry of the heel and the outline of the ankle is unim- paired, but the forepart and dorsum of the foot are greatly swollen, glazed, and possibly perforated by sinuses discharging thin unhealthy pus. I look upon this disease of the anterior tarsal synovial membrane as a distinct affection of the 632 ON EXCISION OF JOINTS AND BONES. foot, requiring to be diagnosed from the other strumous inflammations, and in its advanced stages requiring Chopart's amputation. The phalanges and articulations of the toes seldom require resection; as a general rule their amputation is preferable. The only case that I am acquainted with in which resection of a phalanx is required, is when an exostosis has formed under the nail of the toe, pushing it up, when the removal of that portion of bone from which it springs, is the best course to pursue. The great toe not unfrequently requires removal in whole or in part; but, entering largely as it does into the formation of the arch of the foot, no more of it should be taken away than is absolutely necessary. It is especially of importance that the ball of the great toe be, if possible, preserved; and occa- sionally this may be effected by excision of the metatarso-phalangeal articulation rather than by the amputation of the member. With regard to the removal of the toe and its metatarsal bone, I must refer to p. 55. Whenever it is practi- cable the proximal end of the bone should be saved, in order that the insertion of the tendon of the peroneus longus may be preserved. The other metatarsal bones with their toes occasionally require removal. This is more particularly the case with the fifth. The middle metatarsal bones cannot advantageously be taken away, leaving merely the first and last; but the two, three, or even the whole four of the external metatarsal bones may be advantageously resected, and a useful foot be left. Mr. A. Key has recorded a case in which, in consequence of injury, he amputated the four outer metatarsal bones, the cuboid, and the external and middle cuneiform, leaving merely the line of bones supporting the great toe. The first metatarsal bone was left, sup- ported only by the slender articular surface of the internal cuneiform, but it soon got firmer attachments, and a very good foot resulted, by which the patient retained in a great measure his elasticity of tread. The os calcis, from its exposed situation, large size, and spongy structure, is more frequently the seat of caries and necrosis than any of the other tarsal bones; and very commonly the morbid action is limited to this bone; in other instances it extends into the calcaneo-astragaloid or calcaneo-cuboid articu- lations. When the disease is situated in the posterior or lateral parts of the bone, the neighboring articulations are seldom involved, and then the removal of the morbid structures by gouging will usually succeed in effecting a cure. I have frequently had occasion in this way to scoop out great portions, some- times the whole of the interior of the calcaneum, with the most excellent results. If the upper or anterior portions of the bone are diseased, so as to involve its articulations with the astragalus and cuboid, its excision should be practised. The operation is a very successful one, and leaves a flat but useful foot. Occa- sionally, however, after the removal of the bone, disease is set up in the neigh- boring parts requiring amputation; this I have seen more than once happen; and, of 10 cases collected by Mr. M. Greenhow, it became requisite in 2 even- tually to remove the foot. The excision of the os calcis is usually performed by turning a heel-flap back as in disarticulations at the ankle joint, and then carrying incisions forward into the sole of the foot, by which another flap is turned up, and thus the calcaneo- cuboid articulation exposed and opened (fig. 30); after which the knife is car- ried between the astragalus and calcaneum, and that bone detached. By this operation the sole of the foot is somewhat extensively incised and cicatrices are left over the heel. In order to avoid this inconvenience, I have found that disarticulation of the os calcis may readily be performed in the following way. The patient lying on his face, a horse-shoe incision is carried from a little in front of the calcaneo-cuboid articulation round the heel, along the sides of the foot, to CONSERVATIVE SURGERY OF THE FOOT. 633 a corresponding point on the opposite side. The elliptic flap thus formed is dissected up, the knife being carried close to the bone, and the whole under surface of the os calcis Fig. 229. thus exposed. A perpendicular incision about two inches in length is then made behind the heel, through the tendo Achillis in the mid line and into the horizontal one. The tendon is then detached from its insertion, and the two lateral flaps dissected up, the knife being kept close to the bones from which the soft parts are well cleared (fig. 229). The blade is then carried over the upper and posterior part of the os calcis, the articulation opened, the interosseous ligaments divided, and then by a few touches with the point, the bone is detached from its connections with the cuboid, which, together with the astra- galus, must then be examined, and if any disease is met with the gouge should be applied. By this operation all injury to the sole is avoided, and the open angle of the wound being the most dependent, a ready outlet is afforded for the dis- charges. The astragalus though often diseased is rarely affected without the neighboring bones partici- pating in the morbid action. It is so wedged in between the arch of the malleoli above, the calca- neum below, and the tarsal bones in front, that it is not long before disease spreads from it to the contiguous articulations and osseous structures. Disease primarily originating in the astragalus may spread in three directions: upwards into the ankle-joint, downwards to the calcaneum, and for- wards to the scaphoid, and thence through the large anterior synovial mem- brane to the rest of the tarsal bones. The treatment will vary according to the direction and extent of the disease. It may be arranged under four heads. 1st. When the astragalus alone is diseased, either gouging or excision may be required. If the morbid action be limited to the outer side of the bone, or to its head, it is possible that by freely opening up the sinuses and applying the gouge, the caries may be entirely removed. But this operation is not so satis- factory here as elsewhere in the foot, as it is by no means easy to avoid opening the astragalo-scaphoid articulation, and if this is done, disease will almost inevitably extend through the tarsal articulations. Excision of the astragalus alone, though sometimes required for disease, is perhaps more frequently called for in those cases of compound dislocation in which the bone, having been thrown out of its bed, eventually becomes carious or necroses. The operation may readily enough be done by making an incision across the outer and anterior aspect of the ankle, exposing the bone, cutting across its neck with pliers, and then with strong forceps forcibly elevating it from its bed and detaching it by the cautious application of the knife, more particularly to the inner side, where the plantar arteries are in danger. The result of this operation is very satis- factory, a good and movable articulation may be left between the malleoli and calcaneum, and the limb is but little shortened. 2d. When the disease has extended from the astragalus to the malleolar arch, excision of the ankle-joint will be required. This operation may con- veniently be performed in the following way. A semi-lunar incision about four 634 ON EXCISION OF JOINTS AND BONES. inches in length should be made along the outer and anterior aspect of the joint, round the lower bor- Fig. 230. der of the exter- nal malleolus (fig. 230), and should be carried sufficiently forwards to give space without dividing the extensor tendons or the dorsal artery. The peroneal tendons having been divided, the lower end of the fibula should be cut across and detached. The astragalus which will now be exposed, should then be se- parated from its con- nections, which, if it be much diseased, may usually be readily done. If not deeply affected it will be more firmly held, and should be then cut across with pliers, and each fragment lifted out of its bed. The foot should now be well drawn to the inner side, the lower end of the tibia carefully isolated, the knife being used with great caution and kept close to the bone, lest the posterior tibial artery be injured. When the ligamentous structures attached to the bone have been separated, the inner malleolus may be cut off with bone forceps, and as much as necessary of the lower end of the tibia removed with a narrow- bladed or a chain-saw. Should there be any disease in the articular surfaces of the calcaneum or scaphoid this must be gouged away. The part should then be lightly dressed, and the limb placed on a Liston's splint. 3d. When the disease has extended to the calcaneum from the astragalus, amputation at the ankle-joint may be required, or should the surgeon prefer it, he may excise both the diseased bones, as has been successfully done by Mr. T. Wakley. 4th. If the disease has extended from the astragalus to the scaphoid, and thence into the anterior range of tarsal joints, the foot will have become so extensively disorganized, that partial resection will be of little or no service, and disarticulation of the ankle-joint should be practised. Excision of the cuboid bone either in whole or in part may be required; when the whole of the bone is taken away, the fifth metatarsal bone with the little toe will probably also require removal. The scaphoid is very commonly the seat of primary disease, and as this bone is connected in front with the large tarsal synovial membrane and posteriorly with that which is common to the calcaneo-astragaloid and astragalo-scaphoid articulations, the greater part of the tarsus is apt to become speedily involved in the morbid action. The extent of this implication is such that excision of the primarily diseased bone would probably seldom be attended by much benefit, and Chopart's amputation or disarticulution at the ankle-joint becomes neces- sary. Next to disease of the astragalus, I look upon strumous inflammation of the scaphoid as most destructive to the integrity of the foot. In chronic disease of the ankle and tarsal bones, it will occasionally happen that an excellent and useful limb may be left after excision of a less formidable kind than those just described. In a lad who was some time since under my care with very extensive disease of these parts of old standing, I removed the lower three inches of the fibula, gouged away a considerable portion of the end of the tibia, and of the astragalus, calcaneum, and cuboid, removing a whole EXCISION OF THE KNEE-JOINT. 635 handful of carious bone. Yet a perfect cure resulted, the patient recovering with a strong and useful foot. The malleoli alone seldom require resection. Should either of them do so, the operation may readily enough be accomplished,—in the outer malleolus, by dividing the bone with cutting pliers, but in the inner malleolus, more care is required in avoiding the flexor tendons, the artery, and nerve, and the bone had better be cut across with a chain-saw. Excision of the knee-joint may be required either as a substitute for amputa- tion in cases of extensive dis- ease and disorganization of the Fig. 231. articulation, or may be practised in some cases of deformity re- sulting from old disease or in- jury by which the limb has been rendered useless. This operation, originally practised at the close of the last century by Park, Filkin, and the Mo- reaus, fell into disfavor until it was revived in 1850, by Mr. Fergusson, since which time it has been extensively practised. Excision of the knee-joint may be performed by making a horse-shoe incision with the convexity downwards, extend- ing from the side of one condyle of the femur across the tube- rosity of the tibia to a corres- ponding point on the opposite condyle (fig. 231). By this incision, the ligamentum patellae is divided, and that bone turned up in the elliptical flap; the crucial ligaments are then to be cut across, any remaining lateral attachments divided, and the bones cleared for the saw. In doing this the limb must be forcibly flexed, and the knife care- fully applied to the posterior part of the head of the tibia; for this purpose a blunt-pointed resection knife is the best. The articular surfaces must now be sawn off. This may best be done by Butcher's saw. The lower end of the femur should first be removed, and then a slice taken off the tibia by cutting from behind forwards, the blade of the saw being turned horizontally; care should be taken not to remove more bone than is absolutely necessary, lest the limb be too much shortened. As not unfrequently happens, carious cavities will be found extending below the level of the section that has been made. When this is the case, it is better to apply the gouge to them than to saw the bone below their level. It is usually sufficient to remove from one-third to three-fourths of an inch of the tibia, and about one inch to an inch and a half of the femur (figs. 232 and 233). Should, however, the operation be required, for disease of the limb consequent upon the deformity resulting from badly reduced fractures or dislocations about the knee, as has been done successfully by Mr. Humphry of Cambridge, it may be necessary in order to get the limb into good position, to remove a wedge-shaped piece from one of the bones. If the patella is much diseased, it must be removed; if it be only slightly carious, it may be scraped or gouged out, and in accordance with that principle of conservative surgery by which no sound part is removed, it should be left, becoming consolidated with and strengthening the joint. The anterior articular surface of the femur, which extends some way up the fore-part of that bone, 636 ON EXCISION OF JOINTS AND BONES. may advantageously be sliced off, so as to leave an osseous surface instead of a cartilaginous one, for the patella to attach itself to. Fig. 232. Fig. 233. In some cases no ligatures will be required, but usually two or three of the articular arteries furnish sufficient hemorrhage to require restraint. The patel- lar flap when laid down will often appear inconveniently long and thick, but it is better not to curtail it, unless the bones have been shortened more than usual, as it will contract and eventually fit in well. I have always found the operation as I have just described it, easy of per- formance and good in its results, but various modifications are adopted by dif- ferent surgeons. Thus, some make two parallel incisions on either side of the patella or an H shaped incision, and thus open the articulation from the side. That excellent surgeon, Mr. Jones, of Jersey, who has had great experience in this operation, has advised that the skin be dissected up by means of a semilunar incision, and then that the ligamentum patellae be preserved by being pushed with the patella and the quadriceps extensor tendon to one side, the joint then opened and the bones sawn. Others again advise that the patella be removed, and Mr. Holt has recommended that after the excision the soft parts of the ham be perforated to allow the discharges to drain through. The successful issue of the operation will mainly depend on the care taken in the after-treatment of the case. After the operation, the limb should be at once put up securely in a Liston's splint, and well-supported. During the after-treatment, when granulations spring up, it may most conveniently be placed in a long leather trough, extend- ing from beyond the foot to the pelvis, and well padded, particular attention being paid to the position of the limb, and especially to the prevention of any bowing outwards which is apt to take place. In order to prevent displacement it has been proposed to divide the hamstring tendons; this, however, I have never found necessary, nor does it seem to me to be advisable to complicate the operation by such an addition to it. The protuberance of the flap, if at all exces- sive, may be diminished by the pressure of a many-tailed bandage. In this way osseous anchylosis will ensue, and a good and useful straight limb result. In two cases I have succeeded in getting a good limb with a partially movable joint; both these cases were in children, and I am disposed to think that in young patients this result may often be satisfactorily attained. In adults, how- ever, osseous anchylosis should always be aimed at. In determining the propriety of performing this operation, there are two points to be considered : — 1st. The danger attending it; and 2d, the nature of the result. The danger attending excision of the knee-joint is not great when compared to that which follows the operation, amputation of the thigh, instead of which it is practised, or indeed capital operations generally. According to Mr. Butcher, the operation has been performed 82 times since its revival in 1850 up to 1857. Of these 15 proved fatal, and in 8 amputation of the thigh was required, of which 1 case had a fatal issue. In some instances there is reason EXCISION OF THE KNEE-JOINT. 637 to believe that the unsuccessful result was owing to want of due attention to the after-treatment of the case. I think, therefore, we are warranted in concluding that this operation, though serious, is not attended by any very great amount of risk to the patient. The 2d point that has to be determined, is as to the utility of the limb after the operation, the propriety of performing which, depends in a great degree upon whether the limb that is left is more useful than an artificial one. On this point, the result of recorded cases is in favor of the operation. In one of Mr. Park's cases, operated on in 1783, that surgeon states that the patient, a sailor, seven years after the operation, "was able to go aloft with considerable agility, and to perform all the duties of a seaman." In some of the later cases the result has been equally good. One of Mr. Jones' patients, a boy, "could run and walk quickly without any aid of a stick, could stand on the limb alone, and pirouetted and hopped two or three yards without putting the sound limb to the ground." In several of my own cases an excellent strong and straight limb has been left, useful for all ordinary purposes. After the operation, osseous anchylosis takes place with a firm cicatrix, the limb is shortened by from two to three inches, but by means of a high-heeled shoe this inconvenience is greatly remedied. It has been urged against the excision of the knee-joint that convalescence is tedious and prolonged, but this argument can with justice have but little weight; if a useful limb can be preserved to the patient, it can matter but little if a few additional weeks are devoted to the procedure by which it is obtained;—and, indeed, it is a question, whether in many cases the patient may not be able to walk just as soon after the excision of the knee-joint as after amputation of the thigh; for as has been very properly remarked, though the amputation wound may be healed in three or four weeks, it may be as many months before an artificial limb can be worn. Excision of the head of the femur has of late years been a good deal talked about and practised in some cases of hip-joint disease. This operation may, however, most conveniently be considered in connection with that affection (P-657). Amputation in joint-diseases. — In those cases in which excision of the dis- eased joint is not advisable, in consequence of the acute character of the arti- cular disease, the existence not only of considerable suppuration, but of great local and constitutional irritation, or the peculiar nature of the joint affected, amputation may be the sole resource left to the surgeon. It is especially in articular disease of the fingers and toes, of the tarsus, carpus, ankle, and knee, that this operation is required; and though much less frequently practised now than formerly, yet the cases of destructive disease of joints requiring amputa- tion are amongst the most frequent in operative surgery, and will doubtless continue to be so. The surgeon, however, must be careful whilst he avoids continuing to make ineffectual attempts to save the limb at the great hazard of the patient's life, not to amputate until it is clear that all other means have failed, the patient continuing to lose ground, so that a further perseverance in local and constitutional treatment would probably end in his death, excision not being practicable. So far from amputation being an opprobrium to surgery in such cases as these, I look upon it as one of the greatest triumphs of our art, that by a simple and easy operation which removes the spoiled and useless limb, the life of the patient may be saved, and his health speedily restored. It commonly happens that a patient who has been racked with pain, and been wasting in body for weeks before the local source of irritation was removed, sleeps soundly the night after the operation, and rapidly gains flesh and strength. As phthisis not unfrequently co-exists with the advanced forms of strumous joints, the question of amputation under these circumstances becomes one of 638 DISEASES OF JOINTS. very considerable importance. If the phthisis be rapidly progressing, and there be a strong hereditary tendency to the disease, or if it have advanced to softening of the lung, and the formation of vomica, it would be useless to operate. If, however, the phthisis be of a very slight and incipient character, and be apparently due to the local irritation of and discharge from the diseased joint, to the confinement to bed that it necessitates, and to the general depravation of health that ensues, amputation may not only be safely, but advantageously practised; and I have performed it in many such cases, to the manifest advantage of the patient. LOOSE CARTILAGES IN JOINTS. It sometimes happens that in the interior of the joint the synovial membrane assumes a warty condition, as the result of chronic irritation of the articulation. For this condition, which gives rise to occasional uneasiness and puffiness about the joint, with a crackling or creaking sensation when it is moved, but little can be done beyond the application of discutient plasters and the use of elastic bandages. Loose cartilages, as they are termed, are not unfrequently met with in the different articulations. These in many cases are not truly cartilaginous, but appear to be composed of masses of condensed and indurated fibroid tissue, not very dissimilar in structure to the warty synovial membrane just referred to. In other cases, however, it is probable that they may be of a truly cartilaginous formation. These bodies vary in size from a barley-corn to a chesnut; when small, being rounded in shape; when large, being somewhat flattened or de- pressed on the surface; they are smooth, sbining, and usually of a yellowish or greyish white color. They are most frequently met with in the knee, but not uncommonly occur in the elbow or the joint of the lower jaw, and occasionally in the shoulder. Most commonly only one is found, but their number may range from this up to fifty or sixty. They commonly give rise to very severe pain in particular movements of the limb. This comes on suddenly, prevents the patient either straightening or flexing the joint completely, and is often so intense as to cause faintness or sickness. It is usually followed by a degree of synovial inflammation and by relaxation of the ligaments. These attacks of pain and of sudden irritability of the part come on at varying intervals, as the result of movements of it; they commonly happen in the knee whilst the patient is walking. It is difficult to say to what this severe pain is due. Richet thinks it may be owing to the synovial membrane being pinched between the foreign body and one of the articular surfaces. In some cases the loose cartilage can be felt by carrying the finger over the joint, when it may be detected under the capsule, slipping back perhaps when pressure is exercised upon it. The treatment consists in supporting the joint with an elastic bandage or knee-cap, so as to limit its movements, and thus prevent the liability to the recurrence of the attacks of pain. Any inflammatory action that has been excited requires to be subdued by proper antiphlogistic treatment. If it occasion great and frequent suffering, so as to interfere seriously with the vitality of the limb, and if the cartilage appear to be of large size, and single, means may be taken for its extraction. No operation, however, should be undertaken with this view so long as the joint is in an irritated state, as the result of a recent attack of pain; this must be first subdued, ami then the operation may be proceeded with. The extraction may be effected by directing the patient in the first instance to make those movements by which he usually gets the cartilage fixed in the joint. So soon as the surgeon feels it (as this operation is commonly required in the knee) he should push it to one side of the patella, where he must fix it firmly with his fore-finger and thumb; he NEURALGIA OF JOINTS. 639 then draws the skin covering it to one side, so as to make it tense, and cuts directly down upon the cartilage by a sufficiently free incision to allow of its escape. The wound which, when the skin is relaxed, will be somewhat valvular, is then closed by a strip of plaster, and the limb kept at rest for a few days until it has united. Severe inflammation of the joint less frequently follows this operation than might have been expected, the synovial membrane having probably undergone some modification of action that renders it little liable to this process. It does however happen that acute synovitis may set in, and this has terminated in suppuration of the joint, requiring amputation, or leading to anchylosis; hence it is an operation that should not lightly be undertaken. It has been proposed by M. Goyrand, in order to obviate the dangers of an external wound into the joint, to remove the loose cartilage by subcutaneous section; this he proposes to accomplish in a way that I have seen practised by Mr. Liston; viz., by passing a tenotome obliquely under the skin after fixing the foreign body in the way that has already been described, dividing the synovial membrane freely, and then squeezing the cartilage into the cellular tissue outside the joint, where it may be allowed to remain until removed by a fresh incision after that in the synovial membrane has healed, or left and be eventually taken up by the absorbents of the part. A useful modification of this method consists in fixing the loose cartilage, dividing the capsule subcutaneously over it, and then pressing the foreign body into the opening thus made, retaining it there by a compress and plasters. Adhesion speedily ensues, and eventual absorption of the loose cartilage. NEURALGIA OF JOINTS. Severe pain may occur in joints without organic disease, either from the pressure on a nerve leading to the articulation or distributed in its vicinity, or from some neuralgic condition of the joint itself. Thus there may be severe pain in the knee in consequence of pressure being exercised upon the obturator nerve, or the joint generally may be excessively painful — especially in girls or young women — owing to some hysterical condition or uterine irritation, the nature of which in many cases is not very clear. It is this class of cases, occurring in hysterical females, that should especially be considered as neuralgia of the joints, to which the attention of the profession has principally been directed by the labors of Sir B. Brodie. In these cases it is generally found that the hip, knee, ankle, or shoulder is the joint affected — the hip and the knee being especially liable to it — severe pain is complained of in it; and it is rendered comparatively useless, often with a good deal of distortion. On examination it will be found that the pain, which is commonly very severe, is superficial and cutaneous, not existing in the interior of the articulation or increased by pressure of the articular surfaces against one another, and is not strictly confined to the joint, but radiates for some distance around it. This pain is often intermittent in its character, and is frequently associated with neuralgia elsewhere, as in the spine; and not unfrequently with uterine irritation or disease. At the same time it will be observed that all the signs that ought to accompany a severe attack of inflam- mation in a joint, such as would be attended by a corresponding amount of pain, are absent; there being no painful startlings of the limb at night, or constitutional fever and irritation; and the suffering being increased by causes, such as mental and emotional disturbance, that do not influence organic disease. Attention to these various circumstances will usually enable the surgeon to diagnose the nature of the attack without much difficulty; the only cases in which he will really experience any, being those in which the tissues around the joint have been thickened, indurated, and altered in their characters by the 640 DISEASES OF THE SPINE. application of issues, moxae, &c.; or by some slight articular ties having at some time existed, but been cured. The treatment must be of a general character, directed especially to re-estab- lish a healthy condition of the uterine organs. If there be amenorrhcea, and anemia, aloetics, and the preparations of iron must be given; if uterine irrita- tion or ulceration exist, this must be removed by proper local means, and the general health attended to. The most efficient treatment that can be directed to the affected joint, is, I think, the application of cold douches and the employment of electro-magnetism, which I have found to cure cases in which all other means had failed; the application of atropine and aconite may be of service to allay the pain when especially severe. CHAPTER XLV. DISEASES OF THE SPINE. Caries of the vertebre.—This disease, which consists, in its full development, in destruction of the bodies of the vertebra?, with disintegration of the inter- vertebral fibro-cartilage, most commonly occurs in young children, sometimes but a few months old; but is not unfrequently met with at all ages up to that of thirty. It is always, I believe, a strumous affection, consisting essen- tially in tubercular infiltration of the bodies of the vertebrae, followed, as commonly happens, in this morbid condition, by congestion, caries, or necrosis of the osseous tissue that is in contact with, or the seat of, the deposit. In consequence of these changes going on in the bodies of the vertebrae, they become thinned, eroded, and gradually hollowed out anteriorly. The disease is usually limited to the bodies of the vertebrae, leaving the spines, the arches, and the tubercles unaffected; but in some in- stances even these structures, which are of a more compact character, be- come eventually implicated. In this way the bodies of from three to six or eight of the vertebrae maybe destroyed, the corresponding intervertebral fibro- cartilages, which derive their supply from the contiguous bones, becoming disorganized, as these undergo de- struction. These changes commonly occur about the middle dorsal ver- tebra?; if extensive, they may implicate the upper or lower dorsal, or upper lumbar, and always give rise to angular projection backwards of the diseased CARIES OF THE SPINE. 641 part of the spine, corresponding in extent to the amount of destruction of the vertebrae (fig. 234). The mechanism of this excurvation, which is the most marked feature in this disease, is easily understood by reference to the pathology of the affection. The bodies of the vertebrae being thinned and weak- ened, at last give way under the pressure of the weight of the upper part of tho body, and the remains of the disintegrated bodies being fused together, cause the upper part to bend over, and the spines to project posteriorly. The degree of bending forwards and of posterior excurvation corresponds to the amount of the destruction of the bodies of the vertebrae. It is seldom that the spinal marrow becomes compressed or injured during the progress of this disease. In some cases, however, more particularly in adults, it becomes softened opposite the seat of curvature, and thus paralysis may be occasioned. The symptoms of the disease, when it is fully developed, are well marked; but in children it often comes on very insidiously, commencing with a degree of weakness in the back, with an inability to stand upright, and with a tendency to lean the body forwards, or to support it by resting the hands on the knees, or seizing hold of anything that will serve as a temporary support. On examina- tion, a few of the spines about the middle of the back will be found to be a little more prominent than the rest, and on pressing or tapping upon them pain will be complained of. The child usually becomes stunted in its growth, and if the disease is not arrested by proper treatment, continues more or less hump- or round-backed for life. In other cases it will run on to the formation of abscess, as will immediately be described, strumous manifestations occurring elsewhere, and death eventually resulting. In adults, the symptoms will vary somewhat according to the seat of the affection. It is most dangerous and rapidly fatal when the cervical vertebrae are implicated, for, as the bodies of these are shallow, caries readily penetrates to the spinal canal, and the cord may thus be irritated. When the dorsal or lumbar vertebras become diseased, the affection is not of so immediately serious a character to the life, though it, may be to the figure, of the patient. In adults it often commences with pain in the loins or back, apparently of a rheumatic character, shooting round the body or down the thighs. On examining the spine, which feels weak to the patient, tenderness on pressure or on tapping will be experienced at one point, and he will wince when a sponge wrung out of hot water is applied to this part, although there may be no appearance of excurva- tion. The lower limbs now become weak, and the patient walks with a peculiar shuffling, tottering gait, the legs being outspread, and the feet turned out. The weakness of the limbs is especially marked in going upstairs, and may be tested by directing the patient to stand unsupported on one leg, and raise the other so as to place the foot upon the seat of a chair, which he will probably be unable to do. The deformity of the spine now slowly increases, the patient becomes unable to stand, and spasms of the muscles of the lower extremity come on, together with a tendency to relaxation of the sphincter ani, and retention of urine. Abscess now commonly makes its appearance, and in some cases it occurs before any of the other signs, except pain and weakness of the spine, but certainly before any deformity has taken place. When the abscess forms, as Mr. Stanley has observed, the pain and irritation of the spinal cord are usually lessened for a time. It must not, however, be supposed that abscess necessarily forms in all cases; indeed, the formation of matter will, I believe, chiefly depend upon whether the disease of the vertebrae be tuberculous or not. Simple congestive or inflam- matory caries of the spine may take place to a very considerable extent, and yet no suppuration occur, the bodies of the vertebrae undergoing erosion, and absorption, and coalescing so as to become fused together into one soft and friable mass of bone, across which bridges of osseous tissue are sometimes thrown out, so as to strengthen the otherwise weakened spine. In these cases 41 642 DISEASES OF THE SPINE. masses of porcellanous deposit will not unfrequently be found intermixed with and adherent to the carious bone. Indeed, this anchylosis and fusion of the bodies of the diseased vertebrae may be looked upon as the natural mode of cure of angular curvature of the spine; the only way in which it can take place when once it has advanced to any considerable extent. When abscess forms in connection with diseased spine, it is probably the result of the continued irritation of the tuberculous deposit, and it may become the most prominent and marked feature of the affection, giving rise almost to a distinct and independent disease. The situation and course of these abscesses depend entirely upon the part of the spine affected; thus, for instance, when the cervical vertebrae are diseased, the abscess may come forwards behind the pharynx, and may occasionally extend under the sterno-mastoid muscle to the side of the neck, where it opens; sometimes, though very rarely, it may pass into the chest, and in other cases down into the axilla. When the disease is seated in the dorsal vertebrae, it usually passes forwards under the pillars of the diaphragm down the side of the aorta and the iliac vessels into the iliac fossa, and then presents through the anterior wall above Poupart's ligament. In other cases, again, when the lower dorsal or upper lumbar vertebrae are dis- eased, the pus gets into the sheath of the psoas muscle, thus constituting the common affection termed "psoas abscess;" and passing along this, under Pou- part's ligament, presents in the thigh; or it may continue its course downwards, burrowing under the muscles of this region, until it reaches the popliteal space, and even pass from this some distance downwards on to the calf or ankle. I have seen an abscess opened by the side of the tendo achillis, which took its origin in disease of the dorsal vertebrae (fig. 135). In other cases, again, these abscesses take a different course, and, descending into the sub-peritoneal cellu- lar tissue of the pelvis, may present by the side of the rectum in the perineum, or pass out of the sciatic notch, and down by the side of the trochanter. The quantity of pus contained in these collections is sometimes enormous, and abscesses of this description attain a greater magnitude than those of any other part of the body. In other cases the abscess may follow the course of both psoas muscles, and project on either groin, at the same time. The diagnosis of caries of the spine is made at the first sight of a patient affected by the disease, when once the angular deformity has taken place. It is, however, difficult before excurvation occurs, being only indicated at this period by the existence of pain in the back, and by some symptoms of spinal irritation. At this stage it may be mistaken for spinal or intercostal neuralgia, for rheumatism, or for chronic nephritis. The persistence, however, of a con- tinuous fixed pain in the back should always lead to a suspicion as to the true nature of the disease, lest the grievous error be committed of treating as mere neuralgia or rheumatism, what may turn out to be incurable disease of the spine itself. Here the tenderness on pressure, the increased sensibility to the appli- cation of heat, with a tendency, though it be very slight, to projection of some of the spines, the feeling of weakness in the back, and especially the occurrence of these symptoms in early childhood or youth, at a period when the other dis- eases rarely occur, would lead one to suspect the true nature of the affection. The diaejnosis of the connection between abscesses in the situations mentioned and those arising from diseased spine, is not always easy, as purulent collections of various kinds may form in the different planes of cellular tissue in the neighborhood of the vertebral column, without any disease existing in it, and these often attain a very considerable bulk before they present externally, which they usually do in the groin. Abscess in the groin may arise from the following causes: 1st, from large lymphatic collections in the subcutaneous or intermus- cular planes of cellular tissue; 2d, from disease of the cellular tissue around the kidneys; 3d, from pericoecal abscess (on right side only); 4th, from iliac abscess, whether forming merely in the iliac fascia, or dependent on disease of PSOAS AND ILIAC ABSCESS. 643 the pelvic bones; 5th, from hip-joint disease, the abscess being pelvic; 6th large buboes or glandular abscesses; 7th, from an empyema perforating the pleura and finding its way down behind the diaphragm. The diagnosis of these various collections may, however, with a little caution, be readily made from the ordinary form of spinal abscess that descends along the psoas muscle. In the first place, in all these cases there is an absence of that dorsal pain and tenderness, with more or less excurvation, which, though not invariably present, is commonly met with in psoas abscess. Then, again, if the collection be peri- nephritic, there would have been previous, or there are co-existing, symptoms of renal disease. If it occur in the cellular tissue around the coecum, the pus will be peculiarly offensive, will present itself in a less distinct manner, and will probably be associated with symptoms of intestinal irritation. In those rare cases in which an empyema has found its way between the layers of the abdomi- nal muscles, and presented in the groin, the stethoscopic signs will point out the nature of the affection. In abscess connected with disease of the hip-joint, there will be special evidences of the source of the pus. The only real diffi- culty consists in diagnosing large psoas abscess presenting in the thigh or in other parts of the lower extremity, and dependent on disease of the vertebral column, from iliac abscess taking its origin in the loose cellular tissue of the iliac fossa, whether it be connected or not with disease of the corresponding bone; and in these cases the difficulty is often not a little increased in conse- quence of the iliac abscess finding its way into the sheath of the psoas. In iliac abscess, the disease usually commences at or after the middle period of life, always in adults; and, as Mr. Stanley has observed, usually presents itself externally, immediately above Poupart's ligament, being conducted for- wards to this situation by the fascia iliaca. Psoas abscess, on the contrary, most commonly occurs in the earlier periods of life; extends down into the thigh along the course of the psoas muscle, so that it always presents below Poupart's ligament. It is also commonly associated with some indication of irritation of the muscle in the sheath of which it is situated; thus, there is an inability to stand upright, to extend the leg, and pain is complained of in walking. Psoas abscess, also, in many cases, occurs suddenly, the patient finding, on washing himself in the morning, that he has got a large soft tumor in the upper part of the groin, whereas iliac abscess comes on more gradually, and presents in a more diffused and less circumscribed manner. The prognosis in caries of the spine is always bad; the deformity always continuing more or less marked; and the patient, though he may eventually recover, by anchylosis taking place, continues hump-backed in after-life. Very commonly the disease terminates in abscess and death. It was long ago remarked by Boyer, that the most fatal cases were generally those in which the spine pre- served its straight position; whereas, when it was much curved, death seldom resulted. The truth of this remark I have had frequent occasion to verify; and the circumstance would appear to be owing to the fact, that when the spine con- tinues straight at the same time that the bodies of the vertebrae are tuberculous and carious, anchylosis cannot occur, the spinal canal is opened, and the cord irritated; whereas, when they have fallen together, and very considerable gib- bosity has resulted, anchylosis more readily takes place, and thus an imperfect cure is effected. Treatment. — In infants, the utmost that can be done is to direct that they should be laid prone upon a pillow or small couch constructed for the purpose; that the general health should be attended to by tonics suited to their age; that they should have the advantage of country or sea air; and that some counter- irritant, as the tincture of iodine, should be applied by the side of the spine. In children that are somewhat older, and in adults, great advantage may be derived by strictly forbidding them to walk, stand, or sit erect; confining them rigidly to the prone couch, and adopting a general plan of tonic treatment. At 644 DISEASES OF THE SPINE. the same time counter-irritation may be applied with great advantage by means of caustic issues or moxae to either side of the spine. In fact, the principles of treatment in these cases are extremely simple: the improvement of the general health by good diet, tonics, and sea air, in order to remove the strumous condi- tion with which this disease is always associated, and the employment of counter- irritants suited to the age of the patient, to lessen the local action in the verte- bra), is all that can be done. Rest in the horizontal position is the most important element in the treatment; if the patient be allowed to stand upright or to sit, the weight of the head and shoulders will tend to curve forward the weakened spine, and by their pressure increase the already existing irritation in it. The horizontal position relieves the diseased parts of this additional source of distress. In these cases the prone position is preferable to the supine, and the patient, if old enough, should always be laid upon a properly constructed prone couch, such as was introduced into practice by the late Mr.Verral. This position is certainly the best, for not only is the projecting angle formed by the excurvated spine not injuriously compressed, as it would be in the supine or lateral position, but the patient is more comfortable; and it is far easier to make the necessary appli- cation in the way of issues and moxse than could otherwise be done. At the same time, the back not being the lowest part of the body, there is a less ten- dency to congestion of the spinal veins, and to consequent increase of the inflammatory softening of the bones. When the disease has in this way been arrested, for which many months—at least twelve or eighteen—will be required, the patient may be allowed to get up and move about, by wearing proper stays so as to support the trunk. It is of considerable importance in the treatment of this disease, that the patient should not be allowed to get or sit up too soon, before the consolidation of the diseased vertebrae has taken place, otherwise he will to a certainty suffer a speedy relapse, or the excurvation will greatly increase. If debility of the lower limbs or paraplegia should come on, the administra- tion of the bichloride of mercury in doses from the twentieth to the sixteenth of a grain has been strongly recommended by Latham and Stanley. Issues will also be of use in relieving the nervous symptoms, though they may have had little effect on the disease of the bones. When abscess has formed the surgeon should be in no hurry to open it; but in accordance with the principles laid down when treating of those affections, he should delay doing so, lest injurious fatal constitutional irritation be set up. When it becomes necessary, from the approach of the matter to the surface to give exit to it, this should be done by valvular incision, closed, as soon as the pus has been discharged, by means of hare-lip pins, or in the way described (page 347). The hectic or constitutional irritation that supervenes about this period, must of course be treated on general principles. Disease of the atlas and axis, and of the atlas and occiput, constitutes one of the most serious forms of vertebral caries. In these cases there is pain, swelling, with great difficulty or absolute inability in moving the head; after a time induration of the cellular tissue, with swelling and fluctuation behind the pharynx come on, pushing forwards its posterior wall against the nasal aper- tures, causing the tongue to be extruded, occasioning much difficulty and dis- tress in breathing, and giving rise to a peculiar nasal tone in the voice. The abscess may point here, or extend outwardly under the muscles of the neck. Patients affected by this disease truly present a remarkable as well as distress- ing appearance. The neck being perfectly rigid, they are unable to turn the head, but when they want to look round have to twist the whole body; at the same time, the weakness in the neck usually compels them to support the head with both hands, putting one under the chin, the other under the occiput, and so holding it. The disease often terminates fatally by luxation of the vertebras forwards, compression of the cord and sudden asphyxia, or more slowly by hectic LATERAL CURVATURE OF THE SPINE. 645 and gradual interference with the respiratory functions. The treatment must be conducted on precisely the same principles as that of angular curvature, by absolute rest, counter-irritation and tonics. As groat and immediato danger may result from the sudden displacement of the vertebrae, and the consequent compression of the cervical cord, the head usually requires to be steadied by machines calculated to support it and limit its movements. Disease of the sacro-iliac articulation occasionally occurs. I have had several cases under my care at the University College Hospital, in which the symptoms and post-mortem appearances of the disease were well marked. It commences with pain, tenderness over the junction between the sacrum and the ilium; this is followed by weakness, difficulty in progression, abduction of the limb on the affected side, and some elongation of it from swelling of the affected articulation, and thus a tendency to displacement forwards and downwards of the whole side of the pelvis. After a time abscess forms, which usually acquires a very con- siderable size, extending under the gluteal muscles, and at last, after many months, or even a year or two have elapsed, pointing by the side of the coccyx or into the rectum. Most frequently this disease terminates in death by hectic, consequent on opening the abscess. Sometimes, but very rarely, anchylosis may take place, and then the limb on the affected side may continue perma- nently lengthened, for the reason already adverted to. In the treatment the same principles of rest and counter-irritation must be carried out that constitute the basis of the management of all similar affections. LATERAL CURVATURE OF THE SPINE. This affection, on account of the frequency of its occurrence, and the tedious- ness of its cure, has received a good deal of attention from various surgeons, and much has been written upon it by those who have specially devoted themselves to its treatment, but Fig. 235. yet, the whole of its pathology and management lie in a very narrow compass. Lateral curvature of the spine most commonly commences at an early period of life, usually between the ages of twelve and eighteen; seldom before the one, and not very commonly after the other; it rarely, if ever, occurs but to females, at least I have never heard of, or seen a marked case of the kind in lads. It appears to consist simply in a relaxation of the ligaments and muscles of the spine, in consequence of which the vertebral column, being no longer able to support the weight of the head, neck, and shoulders, becomes curved to one side, a correspond- ing deviation taking place in the opposite direction at a lower portion of the spine, in order to preserve the equilibrium between the two sides of the body (fig. 235). The first curve usually takes place in the upper or. middle dorsal region, the convexity tending towards the right side; the second, or compensating curve, occurs in the lumbar region, the convexity looking towards the left. In some instances there is a quadruple curve. At the same time that these lateral curves take place, there is always a tendency to rotation of the bones of the spine upon one another, in such a way that the bodies of the vertebrae that form the dorsal curve, are twisted slightly to the left, whilst those that enter into the formation of the 646 DISEASES OF THE SPINE. lumbar curve are slightly turned to the right. This twist is sometimes slight, but in such instances it is very marked, so that there is a double curvature, lateral and rotatory. On examining the bones and intervertebral fibro-cartilages after death, even in cases of very considerable distortion, no disease will appear in them, except, perhaps, that the bodies of some may have been slightly com- pressed where they form the principal concavity of the arch. The ligaments appear to be stretched, relaxed, and somewhat weakened in these cases; and the muscles are usually pale, flabby, and apparently wanting in power. From a consideration of the pathology of this affection, and from the par- ticular age at which it manifests itself, before the bones have become completely ossified, or the ligaments have acquired their due degree of rigidity, its me- chanism becomes sufficiently apparent. The spinal column being composed of a number of separate bones, possesses no firmness in itself, or power of self- support, but is maintained in the erect position by the close manner in which its separate elements are knit together by ligamentous and muscular structures, and by the way in which, when thus bound together as a whole, it is supported on either side by the strong mass of the erector spinae muscles. The proper tension of these ligamentous supports, and muscular masses, is especially necessary for it to maintain the weight of the head and shoulders, which is thrown on the cervical and upper portion of the dorsal spine. If, from any cause, the ligaments become relaxed, and the muscles lose their tension, or if the weight of the upper part of the body increase disproportionately to the augmentation in the strength of the ligaments and muscles that support the spine, the vertebral column will necessarily give way under the pressure to which it is subjected in a direct line from above downwards, and will conse- quently become curved. Most commonly, indeed almost invariably, this takes place in a lateral direction, the spine yielding more readily in this than in any other. In some rare cases, however, the lower portion of the cervical, or upper dorsal region, will project backwards in an angular manner, and in other cases, of still less frequent occurrence, there may be incurvation of the spine in the lumbar or dorso-lumbar region. These various kinds of deformity, as has already been stated, chiefly occur in girls about the age of puberty; at a time of life when the tonicity of the mus- cular system not unfrequently becomes lessened by the occurrence of anemia and those states of impaired health that so frequently attend the establishment of the uterine function; and before the osseous and ligamentous structures of the body have fully developed. At this period of life, also, it frequently happens that the spine becomes rather suddenly elongated by a rapid increase in growth taking place, or that it becomes overweighted by the system deve- loping itself, and the shoulders and bust becoming stout and expanded. Indeed, so frequent is the occurrence of a certain degree of lateral curvature of the spine from these various causes, about the age of puberty in girls, that few escape a tendency to deviation, of so slight a kind, however, as not to admit of recognition as a disease. But if this tendency be allowed to go on unchecked, or if it be increased by injurious habits, amongst which all one-sided postures in which the body is twisted, as in playing some musical instruments, or in lean- ing over a table in drawing and writing, the slight deviation may rapidly in- crease until it assumes the true characters of lateral curvature of the spine. I do not think that there is any evidence to show that this is either a strumous or a ricketty affection; indeed, so far as my observation goes, I should certainly say that strumous girls are less liable to the disease than those of a nervous or bilious temperament. A ricketty tendency would, of course, increase the dis- position to the affection, but I think it is very rarely associated with it. Amongst the more common predisposihg causes must undoubtedly be reckoned the indolent and sedentary occupations, and the luxurious enervating habits that are commonly encouraged in girls in the higher ranks of life, and which, LATERAL CURVATURE OF THE SPINE. 647 by preventing due muscular development, at the same time that they induce a general loss of tone in the system, may directly occasion the disease. The signs of this affection, when it is well marked, are distinctly obvious. The serpentine character of the curve, its double nature, the convexity on one side looking to the right shoulder, and on the other, to the left loin, will render its nature evident. Most commonly it commences in a gradual manner, the first condition that frequently attracts attention being the prominence of the right scapula, which is supposed to be " growing out;" or the sterno- clavicular articulation on the same side, or some of the cartilages of the ribs have been observed to project. Whenever the surgeon is consulted for such symptoms as these, he should at once examine the spine, which he will gene- rally find to have an inclination to the right side. In the early stages of the disease, when the deviation is not very distinctly marked, the readiest mode of determining it is to let the patient stand upright, taking care that the feet are well placed together, and that the attitude is not forced, but natural; the sur- geon should then run his finger down the back from one spinous process to another, touching each as he passes it with a pen dipped in ink; in this way, when he has reached the lower part, he will have mapped out the course of the vertebral column, and thus may see at a glance the nature and extent of its dis- Fig.236. placement. At the same time he will pro- bably observe that the two hips do not exactly correspond, the left being some- what thrown out. Very commonly there is a good deal of neuralgic tenderness about the spine, and at this early stage there may be anemia and symptoms of impaired nutrition. As the disease advances, the curvature becomes more distinct, and at the same time, owing to the torsion of the column, assumes a slightly angular cha- racter where most convex. The ribs on the right side are thrown out and bulging, and carry up the scapula with them, whilst those on the left are sunk and depressed (fig. 236). In fact, the whole of the right side of the chest and body partakes in the projection of the spine on that side, and thus adds much to the general deformity; whilst the left side of the chest is corres- pondingly hollowed and sunk in. When the disease has advanced in this way, it always occasions great general debility, ema- ciation, and pallor, the nutrition of the body being impaired partly by the com- pression to which the thoracic and abdominal organs are subjected, and partly, doubtless, by irritation set up in the spinal cord, induced by the curvature. During the early part of the disease the spine preserves its flexibility, and whilst the curve is still recent, and the patient young, if the weight of the head and shoulders be taken off, it will at once resume its straight direction. Thus, if the patient be lifted off the ground by raising her up with the hands under the axillae, or if she be laid down on her face on a flat couch, the back will fall into a straight position, or may readily be made to do so by slight traction. After the disease, however, has existed for some years, or if the patient has passed that age at which consolidation of the bones and ligaments takes place, the distortion will continue permanently in whatever position she is placed. This is not only owing to the deformity of the spine, but to the ribs, and liga- 648 DISEASES OF THE SPINE. mentous and muscular structures generally of the trunk, having become fixed in their abnormal position. The treatment of lateral curvature of the spine should be conducted on rational principles, and when divested of the mystery with which some inte- rested specialists have surrounded it, becomes as simple as that of any other chronic surgical affection of the bones, joints, or muscles. There are three principles of treatment that require to be carried out in the management of these cases. The first is the improvement of the general health; unless this is effected, nothing can be done; the second is to strengthen the muscles of the spine; and the third, to take away as much as possible the weight of the head, neck, and upper extremities. The administration of some of the milder prepa- rations of iron, with a course of aloetics for the regulation of the uterine func- tion, is of great moment; at the same time a nourishing diet of animal food should be allowed, and the patient encouraged to take exercise in the open air. By these means the nutrition of the system will be improved, and the tone of the muscles greatly restored. The muscular power may be more directly strengthened by having the back well sponged with cold salt or vinegar and water every morning, and methodically rubbed from top to bottom. The fric- tion should be principally directed to the erector spinae muscles on either side of the vertebral column, and may be done either with the naked hand, or with some slightly stimulating embrocation. At the same time, if the patient's strength will permit of it, but not otherwise, the use of the hand-swing may be allowed, or calisthenic exercises practised; these, however, should not be con- tinued if they induce a feeling of fatigue or exhaustion. Whilst this plan is being persevered in, the patient should be made to lie recumbent for a few hours daily, sitting or standing as little as possible. By these means, assidu- ously continued for some length of time, the muscles of the back may be strengthened, and the increase of the deformity prevented; and in this way the slighter cases of lateral curvature, those in which there is rather a tendency to, than a full development of the disease, may be cured. When the affection is further advanced, though the spine still continues flexible, there being decided projection of the ribs on one side, with prominence of the shoulder and hip, with apparent difference in the length of the limbs, and much impairment of the general health, more decided measures of treat- ment must be had recourse to. In these cases, as in those just described, the constitutional powers must be carefully attended to on ordinary medical princi- ples ; iron, and good living, with fresh air, being the basis of the treatment. At the same time that we endeavor to improve the strength of the system in this way, and that of the muscles of the back, specially by cold bathing and fric- tions, it is essential that we adopt means to take off the weight of the head and shoulders, and to prevent its continuing to keep up, and to increase the deformity. This may be done in two ways: by keeping the patient in the recumbent posi- tion, or by allowing her to go about, wearing proper supports. The recumbent position in the treatment of lateral curvature of the spine, though a valuable means as an adjunct to other measures, has been greatly abused, by being employed as an exclusive plan. This, I think, should not be, except when the patient is unable to stand or walk with comfort, as happens in some of these cases, when it may be necessary to confine her for a time to this position, until the proper muscular power is restored by other means. These instances, however, are very rare; too much so to constitute the rule in the treatment. Whenever the recumbent position is employed, prone seems to me to be far preferable to the supine, for reasons mentioned when speaking of angu- lar curvature of the spine; and the best couch for the purpose is certainly Ver- ral's. The patient should be kept on this during the intervals of exercise, not being allowed to sit or stand, even at meals; she will very soon become accus- SPINA BIFIDA. 649 Fig. 237. tomed to a position that, at first appears constrained, and will, probably, speedily be enabled to sleep on it. The best mechanical contrivance for supporting the weight of the head and shoulders, is Tavernier's belt, either in its original form, or as modified and represented in the accompanying wood-cut (fig. 237). By it, the projection of the right shoulder may be gradually brought down, the left one raised, and the weight of the whole of the upper part of the body sup- ported. By this contrivance alone, properly and carefully adjusted to the condition of the deformity, many patients may be treated without the necessity of any confinement whatever; the spine being gradually restored to its proper direction by very gradually in- creasing the pressure and support of the instrument, at the same time that the gene- ral health is carefully attended to, and the patient has the benefit of sea-air. In the majority of cases, however, I think it is well to conjoin the use of this instrument with that of the prone couch; the patient sleeping on the couch, or reclining on it at meals and when in the house, whilst she wears the belt out of doors, and for the purpose of exercise; taking care to apply it and take it off in the recumbent position. In this way many severe cases of spinal curvature may be successfully treated without interfering with the patient's education, or her usual habits. In long-standing cases of deformity of the spine, when its flexibility is lost, and the projection of the ribs has become per- manent, the patient will derive great com- fort and support from the use of this excellent instrument, and the increase of the disease may thus be prevented, even if direct amelioration be not effected. SPINA BIFIDA. It occasionally happens from congenital malformation that the spinous pro- cesses of some of the vertebrae are deficient, and their laminae either absent or separated; in consequence of this the meninges of the spinal cord in this situa- tion are unprotected, and project through the aperture in the bones, giving rise to a tumor at the part where the arrest of development in the osseous structures occurs. This tumor is usually of an oval shape, its long axis corresponding to that of the spine. It is generally met with about the size of a walnut or an orange, but occasionally attains an immense bulk, equal to that of a child's head. In some cases this tumor is lobulated, having an imperfect septum stretching across it • in other instances two or more of these tumors have been met with in the spine. The skin covering it is usually of its normal color, but when the tumor is of considerable size it may have a bluish or congested appearance, and admit of a certain degree of transparency. On examining the tumor which is hard though elastic when the child is held upright, it will be found that it becomes soft when the child is laid horizontally. It usually becomes tense during expiration, and softer during inspiration. In some cases fluctuation is perceptible and by pressure the bulk may be lessened. Spina bifida may be met with in any part of the vertebral column; it is, however, almost invariably 650 DISEASES OF THE HIP-JOINT. found in the lumbar region, the cases in which it appears higher up being of very rare occurrence, but instances of the kind are mentioned by Cruveilhier. When it occurs high up in the cervical or upper dorsal spine, it has been found that the spinal cord and nerves are usually adherent to the walls of the tumor • when in the lumbar region this is not the case. The prognosis of this affection is necessarily unfavorable, the child usually dying, at an early age, of convulsions. In other cases the tumor increases in size, gives way, and death results from spinal meningitis. In the treatment of spina bifida but little can be done in the way of operation when the tumor is of very large size, and the skin covering it inflamed or ulce- rated ; or when a large portion of the bones appears to be deficient. In those cases, however, in which the child is otherwise healthy and strong, the tumor being of small size at its base, or pediculated, and in which little pain or other inconvenience arises from pressing upon it, some means may be adopted for relieving or curing the deformity. The simplest mode of relief is to employ pressure on the tumor, by means of a compress and bandage; or, what is better, an air-pad, similar to those used for umbilical hernia, and kept in place by an elastic india-rubber band. In addition to pressure exercised in this way, the recommendation of Sir A. Cooper may be followed, and the tumor punctured with a grooved needle from time to time, care being taken, however, to prevent the ulceration of the punctures by cover- ing them with collodion. In this way, by the combination of puncture and compression, cases have been cured. All other plans of treatment, by which the tumor is opened and air allowed to enter it, are fraught with danger, and will, I believe, be inevitably followed by the death of the child from inflamma- tion of the meninges of the cord and convulsions. CHAPTER XLVI. DISEASE OF THE HIP-JOINT. • Hip-disease presents so many points of peculiar and serious importance that it is usually, and not improperly, considered as a distinct affection, apart from other joint-diseases. Like all these it may be of an acute, subacute, or chronic inflammatory character, most commonly occurring in strumous subjects; indeed I think its connection with scrofula is generally more distinctly marked than that of most other affections of the joints. It almost invariably occurs before the age of puberty. Out of 48 cases of this disease, of which I have taken notes, I find that in 16 only did it take place at or after fifteen years of age, and of these, in 6 cases only did it happen above the age of twenty; thus it may be considered essentially a disease of childhood or early youth. It commonly comes on from very slight causes; over-exertion in a long walk, a sprain in jumping, a fall, or sitting in the wet, are usually the circumstances to which its occurrence is attributed. All the inflammatory affections attacking the coxo-femoral articulation are usually confounded under the term " Hip Disease " or " Coxalgia." This is too general an expression; and we shall find included under it several distinct forms of disease that differ from one another in pathology, symptoms, result, and treatment. On looking at the hip-joint in a surgical point of view we find it to be composed of three distinct parts; viz., the soft structures, the acetabulum, and the head of the femur. Any one of these may be principally or primarily SYMPTOMS AND PATHOLOGY OF HIP DISEASE. 651 affected, and we may accordingly divide hip-joint disease into the three distinct forms of arthritic, acetabular, and femoral. This division is not a purely pathological one, but is of a practical character, especially in its bearing on the question of excision. Before proceeding to describe each separate form of coxalgia, we may consider briefly the four pathological conditions which are more or less common to each variety of the affection; viz.,pain, suppuration, dislocat'wn, and anchylosis. 1st. Pain.—The pain in hip-joint disease varies greatly according to the form the affection assumes. In the more chronic forms of the disease it is at first slight, and, perhaps, rather referable to the knee than the hip; this is particu- larly the case in the femoral variety. In the arthritic form it is always very acute, seated in the joint itself and greatly increased by any movement, however slight, of the limb. In the acetabular form of the disease the pain is not at first referred to the joint but rather to the iliac fossa or side of the pelvis; it afterwards becomes severe, gnawing, and deeply seated in the articulation. However slight the pain may be, it is always greatly increased on moving the limb, on pressing the surfaces of the articulation together, or by abduction. Hence the usual position of the patient with the foot raised and merely sup- ported on the point of the toes, the knee and hip being flexed and adducted. 2d. Suppuration is not a necessary consequence of inflammation of the hip- joint, though in strumous subjects it more commonly occurs than not. We often see the arthritic variety of the disease run its course without suppuration, but in the acetabular and femoral, abscess always forms sooner or later. These abscesses usually form behind the joint, under the gluteal muscles; they may open in this situation or burrow under tbe fascia lata, and present on the outer aspect of the thigh below the tensor vagina? femoris. Sometimes they occur in front of the joint under the pectineus, and in the acetabular form of the disease they are commonly infra-pelvic, forming in the iliac fossa, and presenting above or under Poupart's ligament, or passing down by the side of the rectum or through the sciatic notch, and thus finding their way downwards upon the back of the thigh. 3d. Dislocation.—In the advanced forms of hip-disease, dislocation of the head of the femur commonly occurs and may arise from three causes :—1st. The destruction of the joint, the capsular ligament having given way in consequence of inflammatory softening and ulceration, and the head of the bone being thrown out of the cavity by the action of the surrounding muscles. 2d. Caries and partial absorption of the head of the femur may have taken place, so that it no longer fills up the cotyloid cavity, and the ligaments being at the same time destroyed, it slips out on to the dorsum ilii. 3d. A fungous fibro-plastic mass may sprout up from the bottom of the cavity and thus tend to push the bone out of it, and after it has been so extruded, this growth will completely fill the acetabulum. The occurrence of dislocation is, in the great majority^>f cases, preceded by the formation of abscess in and around the joint; but in some instances it hap- pens in consequence apparently of the softening of the ligaments, the head of the bone beino- thrown out of the acetabulum, without the supervention of abscess or any sign of suppuration. In these cases a false joint may be formed upon the dorsunfilii, where the head of the bone lodges. When it is lying in a suppurating cavity it will always be found to be in a carious state, and then no attempt, or at least an imperfect one, is made at the construction of an arti- culation around it. Dislocation takes place chiefly in the femoral variety of the disease, in which the head of the femur is more or less destroyed, and the acetabulum filled with fibro-plastic deposit. In the acetabular form, the head of the bone is not thrown out of the cavity, which is carious, and which becoming at last perforated, may allow the upper end of the femur to slip into the pelvic cavity. 652 DISEASES OF THE HIP-JOINT. 4th. Anchylosis may occur either with or without previous suppuration. If the joint has suppurated and the head of the bone is thrown on the dorsum ilii, a false joint may eventually form, or osseous anchylosis in a more or less faulty position take place. If the head of the bone continue in the acetabulum with- out suppuration, osseous anchylosis (fig. 221) may ensue with but little short- ening of the limb. The Arthritic form of hip-joint disease may commence in any of the soft structures of the joint, in the capsule, the synovial membrane, the cartilages, or the ligamentum teres. Mr. Aston Key believed that the ligamentum teres was very frequently the starting-point of inflammation of the hip-joint, and other surgeons have referred its origin to each of the other structures men- tioned. Without denying the possibility of disease sometimes commencing in the ligaments, illustrative of which we have a beautiful model in the Museum of University College, I believe that it more frequently commences in the car- tilage incrusting the head of the femur, for though it is extremely difficult to prove this, opportunities of dissecting this form of hip-disease in its early stages being very rare, yet the symptoms that attend it so closely resemble those accompanying the diseases of this structure in other joints, that it is difficult not to infer that this may be the case in the hip. In this form of the disease the patient is seized with signs of acute inflam- mation of the joint, coming on pretty rapidly, and with great constitutional disturbance and pyrexia. The pain in the joint in these cases is of the most excruciating character, accompanied by spasms and twitchings of the limb, and marked by nocturnal exacerbations. The suffering is so intense, that the patient cannot bear the slightest movement of the limb; a fit of coughing, the weight of the bed-clothes, or the shaking of the bed by a person leaning against it, will give rise to the most intense agony; and in the intervals of his suffering the patient is in constant fear of a return of the pain, to which he looks for- ward with much anxiety. In these cases the limb is everted, abducted, per- fectly helpless, and motionless; the nates will be found flattened, and there is usually some fulness about the anterior part of the joint, under the pectineus muscle, or to its outer side, above the trochanter. There is also sometimes true elongation of it in consequence of the capsule becoming distended with fluid, and pushing the head of the bone downwards. On measuring the limb, in order to ascertain its true length, it is necessary to examine the two together, and to place the sound in exactly the same position as the diseased one; unless this be done, error will very probably creep in, for on measuring the lower extremity, from the anterior superior spine to the lower border of the patella or the inner malleolus, it will be found to be of greater length when adducted or extended than when abducted or bent. In some cases the distension of the capsule with synovial fluid, as the result of the inflammation in the joint, may be so great as to lead to its rupture, and to the sudden dislocation of the head of the bone on to the dorsum ilii, with great pain and much shortening; this, however, is of very rare occurrence, the dislocation seldom taking place until after abscess has formed within the joint, and the articulation has been thus destroyed. In this, the acute form of hip- disease, various terminations may take place; the result depending greatly upon the constitution of the patient, and the manner in which the affection is treated. Under the most favorable circumstances, as the inflammatory action is subdued, the disease falls into the subacute condition, and recovery gradually but very slowly takes place, with a limb that continues somewhat stiff and partially anchylosed, as well as wasted and somewhat shortened from disuse. Sometimes, complete anchylosis occurs without the previous formation of abscess. In other, and the majority of instances, abscess forms, and then the patient may either be worn out by the continued irritation of diseased bone, or by the pro- fuseness of the discharge; or great shortening taking place either by the SYMPTOMS AND PATHOLOGY OF HIP DISEASE. 653 absorption of the head of the bone, or its dislocation out of the acetabulum, the cavity of the abscess may ultimately contract, the carious portions of bone exfo- liate, and the sinuses close after years of suffering. Under the most favorable circumstances, when once the joint has been acutely inflamed, a year or two will elapse before the patient can use his limb with any degree of security. The safety of the patient depends in a great measure on preventing the occur- rence of suppuration. If the constitution be of a very strumous character this can rarely be done, but if tolerably healthy, the disease may be prevented passing on to this stage, and then the patient may recover with a useful, though somewhat stiff and crippled limb. If suppuration occur, it is very seldom that an adult patient recovers, hectic and exhaustion speedily carrying him off. The life of children may, however, be saved even under these circumstances; but they will be left permanently lamed. In the acetabular form of the disease, the first serious symptom is often abscess in the iliac fossa, with pain around the hip rather than in the joint itself. This however becomes tender on pressure, the patient cannot bear on the limb, but no alteration in its length takes place, although it becomes greatly wasted. The abscess which was at first intra-pelvic soon passes down under Poupart's ligament, or finds its way by the side of the rectum, or through the sciatic notch into the gluteal region. Hectic comes on, the sufferings become greatly increased, and death from exhaustion speedily ensues in this, which I believe to be the most fatal form of hip-disease. In the femoral form of coxalgia, the disease usually commences in a very insidious manner. It assumes a subacute character, and is chiefly met with in young children. The first symptom that usually attracts attention is that the child limps and walks in a peculiar shuffling, hopping manner; he does not stand firmly upon both feet, but rests on the toes of the affected one, the knee of which is bent. On examining the condition of the limb it will be seen to be everted, somewhat abducted, slightly flexed upon the thigh, with the knee partly bent, and apparently shorter than the other. This shortening, however, is apparent and not real; for on laying the child on its back, it will be found that the pelvis is placed obliquely; the anterior superior spine on the affected side being raised to a higher level than that on the sound one, and at the same time turned somewhat forwards; measurement of the limb from this point to the ankle, will show that there is no alteration in its length. The obliquity of the pelvis, which is of very early occurrence in diseased hip, is owing to the child lifting the foot off the ground in order to avoid pressing on it in walking or running, and in doing this he is obliged to raise, not only the limb, but the corresponding side of the pelvis. This apparent shortening will commonly give place, after keeping the child in bed for a few days, to a simulated elongation of the limb; the pelvis on the affected side descending below its natural level. At the same time that these symptoms are noticed, the child usually complains of pain in the hip, especially on pressing over the pectineus muscle, or behind the trochanter; this is increased by standing, walking, or any attempt to bear upon the joint; abduction also, and rotation of the limb outwards, is particu- larly painful, and any concussion of it, as by striking the heel or knee, will greatly increase the suffering. At this stage of the disease, the patient will often refer to the knee rather than the hip as the seat of pain, and a careless surgeon might be misled and treat the wrong joint; the more so as there is not unfrequently a good deal of cutaneous sensibility about the inner side of the knee-joint. This pain appears to be seated in the obturator nerve, the articular branch of which sent to the hip-joint becoming implicated in the disease, com- municates a radiating pain that is felt at the extremity of the long descending branch which is distributed to the knee. On turning the child upon its face it will be observed that the nates are somewhat flattened, the fold being in a great 654 DISEASES OF THE HIP-JOINT. Fig. 238. S>> measure obliterated, and, if it be a female, the vulva on the affected side will be seen to be placed at a lower level than on the sound one. As the disease advances, abscesses may form at any part in the vicinity of the joint. They most commonly occur under the glutei muscles, but sometimes at the anterior part, under the pectineus muscle. When in this situation, they occasionally give rise to very severe suffering down the inner side of the thigh by exercising pressure upon the obturator nerve, which may sometimes become tio-htly stretched over the subjacent cyst of the abscess. It is about this period that true shortening of the limb takes place, which at the same time becomes adducted and inverted, thus assuming a very different position to what it pre- sented in the early stage of the disease. The different positions into which the limb falls in the two stages of the complaint are evidently due to alterations in the muscular action brought to bear upon it. In the early stage, these strong external rotators, which are in close relation with the joint, become irritated by the extension of inflammatory action to them, or by the pressure to which they are exposed by the distended capsule; and hence, being called into increased action, the limb is everted, at the same time that it is slightly flexed and adducted by the irritation to which the psoas and iliacus are subjected. As the disease advances, these muscles become wasted, undergo fatty degeneration, absorption, or disintegration, by the formation of abscesses underneath and around them; hence, the action of the adductor muscles being no longer counterbalanced, the limb is drawn upwards and forwards, and turned inwards (fig. 238). The shortening of the limb may arise, in very chronic cases, from general atrophy of the member, consequent upon disuse; and this, no doubt, in all instances, after a time, in- fluences its condition. Most commonly, however, it oc- curs from absorption of the head of the bone, and in other cases from its dislo- cation upon the dorsum of the ilium. In these cases, the remains of the dislo- cated head can be felt through the thin and weak- ened muscles in its new situation, and in other in- stances may be felt lying at the bottom of a cavity in a carious state (fig. 239). After the formation of abscesses, the health, which may up to this time have kept pretty good, speedily gives way, exhaustion and hectic coming on, and the patient, perhaps, at last sinking from the wasting influence of the diseased bone, and the discharges it occasions. In making the diagnosis of coxalgia, care must be taken not to confound it in its early stages with an ordinary attack of rheumatism; a mistake that not unfrequently happens; the alteration in the shape and position of the limb, the obliteration of the fold of the nates, and the limitation of the pain to the one joint, will usually prevent the surgeon falling into this error. With disease of TREATMENT OF HIP-DISEASE. 655 the knee care must be taken not to confound hip disease, in consequence of the pain in the early stages being commonly referred to that joint; here the absence of any positive sign of disease about the knee, and the existence of all the signs of disease in the hip that have already been noticed, will enable the surgeon to diagnose the true seat of the affection. Lateral curvature of the spine, accom- panied by neuralgic tenderness in the hip, occasionally gives rise to apparent shortening of the limb with pain and rigidity; but in these cases the existence of the spinal affection, the superficial nature of the pain, and the absence of increase of suffering when the joint is firmly compressed, or of painful startings at night, will indicate the true nature of the affection. Abscess may occasion- ally, though rarely, form in the vicinity of the hip without that joint being diseased. Should this take place towards the anterior aspect of the articulation under the pectineus muscle, it may, by its pressure upon the obturator nerve, occasion pain in the thigh and knee, as in those cases in which the articulation is affected; here, however, the sound state of the joint at its posterior and outer part, the absence of all obliquity of the pelvis, and of the other signs of the true hip-disease, will enable the diagnosis to be effected. The treatment of disease of the hip must be conducted with reference to the form of the disease, the acuteness of the attack, and the severity of the local and constitutional symptoms. In all cases this affection must be managed in accordance with those general principles that guide us in the treatment of in- flamed joints. When the disease is of the acute arthritic kind, the patient must of course be kept in bed, and be treated with calomel and opium, pretty freely administered, having a full dose of opiate at night, in order to prevent the painful startings of the limb. The inflamed joint should be leeched, or, if the patient can bear it, cupping-glasses may be applied behind the trochanter; it must also be com- fortably arranged upon pillows, so as to be kept in as easy a position as possible, and great relief will be afforded to the patient by the application of hot poppy fomentations. When the inflammatory action has been somewhat subdued, the joint may be conveniently fixed by means of a leather splint or the starch bandage. Of the two, I prefer the starch bandage, as being more easily applied, and forming a better fitting and more secure casing to the limb. In applying it, the limb should be bandaged from the toes upwards, well padded about the knee with cotton wadding, and the bandage carried in repeated turns round the hip and body in the form of a spica; at the posterior part of the hip it should be strengthened with a piece of pasteboard lined with calico, sufficiently long to extend down the whole of the back of the thigh to below the knee, so as to support that joint also. It is of much importance to do this, as otherwise the hip cannot be kept immovable. In applying this, or any other apparatus, in the more' acute form of the disease, the patient will commonly require to have chloroform administered, as the pain occasioned by the necessary move- ments would otherwise be too severe to be borne. After the starch bandage has well set, a trap may be cut in it opposite any part of the joint to which it may be thought necessary to make applications, and the perineal aspect of the appa- ratus must be well lined and covered with oiled-silk, so as to prevent its being injuriously soiled. In this way the limb may be immovably fixed in a proper position by a light and firm apparatus that will seldom require to be changed during the treatment of the case. When the disease has fallen into a somewhat chronic condition, or from the very first of the subacute or femoral variety, a different and less active line of treatment requires to be pursued. In these cases, rest and perfect immobility by means of the starch bandage are indispensable; in conjunction with this, the employment of counter-irritants, more particularly the caustic issue, will be attended with great advantage; the issues may readily be applied through traps, cut in the apparatus behind the trochanter, and at the forepart of the 656 DISEASES OF THE HIP-JOINT. joint opposite the pectineus muscle. At the same time a course of moderate alteratives and tonics conjoined, will be found most advantageous. To children a powder composed of a grain of mercury and chalk, two grains of carbonate of soda, and three of rhubarb, with or without half a grain of quinine, may be administered twice a day. To adults, the bichloride of mercury in small doses with sarsaparilla or bark will be found most useful. This alterative plan must be persevered in for a sufficient length of time, and as the symptoms of inflammatory action subside, and those of strumous disease manifest themselves more unequivocally, cod-liver oil, with the iodides pf potass or of iron, may be advantageously substituted. During the whole of the treatment, the general health requires careful super- vision, the diet must be attended to, and should be as nutritious as possible, the state of the bowels regulated, the skin kept in good action with a flesh- brush, and the patient reside in well-ventilated apartments. It will very generally be found that the liver is peculiarly apt to get out of order in this disease, the patient becoming jaundiced and feverish; these complications must be treated on general principles. As the health improves, a change to the sea-side will be attended with great advantage, and the patient may be allowed to move about on crutches, having the foot suspended in a sling, as in the case of a fractured thigh. Under such circumstances the best result that can usually be looked for is a stiff joint (fig. 240); Fig. 240. but even if this forms, the patient's condition will be far from unfavorable, for the want of movement in the hip becomes counter-balanced by the greatly increased mobility of the lumbar vertebrae, enabling the patient freely to rotate the pelvis. As abscesses form they should be opened early; no good resulting by delaying to give exit to the pus, which only spreads more widely, disorganizing the soft structures, and means should be taken, by tonic remedies and nourishing food, to keep off hectic. If dislocation has taken place, and the limb consequently becomes a good deal shortened or deformed, being perhaps adducted and inverted so far as to be twisted over the other, or drawn up upon the abdomen, much may be done to lessen the deformity by putting the patient under chloroform, bringing down the limb, and fixing it in a starch bandage. Anchylosis may thus be sometimes got in a good position, and the patient's condition be greatly improved. It is a question whether an at- tempt at reduction should be made in these cases of consecutive dislocation, as it is very rarely that it would prove permanently successful, the acetabulum being either filled up with fibrous matter, or the head of the bone so diseased and lessened in size, that it would not remain in its cavity when put back. Occasionally, however, the re- duction may be successfully effected. In a woman, under my care, at the hospital, with spontaneous dislocation of the hip of about a month's duration, reduction was effected by means of the pulleys, and the head of the bone replaced in the cotyloid cavity, where it remained for some weeks; becoming, however, displaced again in consequence of its being neces- sary to remove a bandage that was applied, as she became affected with inflam- mation of the chest, and could not bear its pressure. If anchylosis is likely to occur, the surgeon must endeavor to secure it with the limb in a straight posi- EXCISION OF THE HEAD OF THE FEMUR. 657 tion. After a stiff joint has formed, the mobility of the lumbar vertebrae will be found to be greatly increased, so that at last the patient will walk with little inconvenience, rotating the pelvis on them. If the anchylosis be not osseous, and especially if the head of the bone be still in the acetabulum, the limb may be straightened by forcible extension under chloroform, and the heel thus brought to the ground. The excision of the head of the femur, in some forms of hip-disease, has of late years been much discussed. This subject has more especially had attention directed to it by the writings of Fergusson, H. Walton, and H. Smith. " But even yet," says Mr. Fergusson, who is one of its greatest advocates, " experience as to the results of this operation is so limited, that I can scarcely say more on the subject than express a belief, that in some instances of disease, and of gun- shot injury of the neck or head of the bone, such a proceeding might be of service." The cases requiring it are necessarily not very numerous. It may, however, be stated, that when the disease is of the femoral kind, being limited to the head and upper end of the femur, the acetabulum and pelvic bones not being involved, but the head of the bone displaced from its cavity, and lying in a carious or necrosed condition on the dorsum of the ilium, with sinuses leading down to it, the patient's general health reduced by hectic, consequent upon the profuseness of the discharge and the irritation of the disease, the surgeon would certainly be justified in cutting down upon, and removing the source of all this mischief, with a view of preserving the patient's life, in accordance with those general principles that guide us in the management of diseased bone in other situations. The cases, however, in which this peculiar combination of circumstances occurs, and in which such an operation would consequently be required, are rarely met with. The great objection to the ope- ration, in the majority of instances, being the extension of disease to the coty- loid cavity and the bones of the pelvis, involving them to a considerable extent, and in such a way as to prevent the complete removal of the diseased osseous structures. Even if the patient's life be not endangered,, the removal of the carious bone may be rendered necessary in order to obtain sound anchylosis between the upper part of the femur and the pelvis, and thus to secure a useful limb to the patient. In hip-disease the acetabulum will be found to possess far greater reparative powers than the head of the femur, so that even when diseased it may recover itself; its disease, when moderate, is therefore no absolute bar to the perform- ance of excision of the head of the femur. In many cases examination with a probe will enable the surgeon to detect the existence of disease in the bones of the pelvis, as well as in the head of the femur; but in other instances it may not be possible for him to do so, the probe not being able to reach the carious bone, owing to the quantity of dense plastic matter that is thrown out around it. Under these circumstances, the question as to the propriety of performing the operation may, to a certain extent, be determined by the position of the head of the femur. If this has been dislo- cated early in the disease, and be lying in a carious condition upon the dorsum ilii, the probability is that the morbid action is confined to it, the acetabulum being filled up with fungoid plastic matter. If, however, the displacement has been of recent occurrence, it is not unlikely that the osseous surface of the cotyloid cavity is involved. If the head of the bone still continue in its socket, the operation should not, generally, be undertaken; for in these cases, if the dis- ease is far advanced, the morbid action will almost invariably have extended to the bottom or sides of the acetabulum. But even in such a case as this, those excellent surgeons, Mr. Jones of Jersey, to whom modern conservative sur- gery is so deeply indebted, and Mr. Hancock, have successfully removed not only the head of the femur but a large portion of the diseased acetabulum. The operation itself is not difficult of performance, the carious head of the 42 658 DISEASES OF THE HIP-JOINT. femur, lying at the bottom of an abscess or of sinuses, may readily be exposed by a X shaped incision over it (fig. 241). Fig. 241. When it is exposed it may be turned out by drawing the limb over the opposite thigh, rotating it inwards and pushing it upwards, when it may be cut off through the neck or trochanter by means of an ordinary saw, or what is better, by pass- ing the blade of Butcher's saw behind and cutting forwards. In planning the incisions, care must of course be taken not to cut too far forwards, lest the an- terior crural nerve be wounded; or too freely backwards, lest a gluteal artery be injured. After the operation the wound must be dressed in a simple manner, and a long splint applied. Mr. Fergusson recommends that the extension should be made from the opposite thigh, round the upper part of which a laced socket is fixed, to which the band is attached (fig. 242). In such cases as these, much advantage will be derived by the use of the bracket thigh-splint. Shortening of the limb will necessarily result, but Fig. 242. as this has already occurred, being the inevitable consequence of all disease of the hip that gives rise to the dislocation of the bone, it need scarcely be taken into account; the operation being rather done with the view of saving the patient's life in the only way that is practicable, than to improve the length of the limb. The result of excision of the hip-joint depends on the extent of osseous dis- ease. When the head of the bone is solely the seat of caries, lying dislocated on the dorsum ilii, the operation may be done with a fair prospect of success. When the acetabulum is but slightly implicated, a portion of its lip being pos- sibly diseased, the gouge may be successfully applied to this, and the result of the operation will not be materially changed. But if the pelvic bones be pri- marily or chiefly affected, and more particularly if the head of the femur be still lying on the cotyloid cavity, with perhaps perforation of the bottom of this and intra-pelvic abscess, little good can be expected or result from an operation for the proper performance of which it would be necessary to remove the greater part if not the whole of the acetabulum, and thus open up the cavity of the pelvis. But that such a desperate operation as this even may be performed with a successful result, is proved by the interesting cases to which reference has just been made; and as the "acetabular" form of hip-disease is necessarily fatal if left to itself, these cases may encourage surgeons in attempting to save the CHRONIC RHEUMATIC ARTHRITIS OF THE HIP. 659 patient by the only alternative open to them. The statistics of the operation are not very perfect, but as far as I can ascertain it has been performed 38 times, with 14 deaths as its direct result. CHRONIC RHEUMATIC ARTHRITIS. A peculiar disease has of late years been described by Mr. Adams and Mr. R. W. Smith, to which the name of " chronic rheumatic arthritis" has been given. It commonly affects the hip, but has been met with in the temporo- niaxillary articulation, and also occurs in the shoulder; at least I have met with cases of disease of this joint presenting all the characters of this affection during life, though as there has been no opportunity of examining Fig. 243. the state of the parts after death, it is impossible to speak positively as to the true nature of the disease. Chronic rheumatic arthritis is an ac- tive disease of the bones and fibrous expansions about the joint, being especially charac- terized by considerable in- crease in the size and by al- teration in the shape of the osseous structures, which be- come porous in some parts, porcellanous in others, with thickening of the fibrous cap- sule of the joint, deposit of masses or plates of bone in it, and ultimate destruction of the cartilages and synovial membranes. The suffering attending the disease is considerable, it greatly cripples the utility of the joint, at last produces incomplete anchylosis of it, and is incurable. CHRONIC RHEUMATIC ARTHRITIS OF THE HIP. This form of the disease commences with a degree of pain and stiffness about the joint, increased at night, and especially in damp or cold weather, presenting in this respect the ordinary characters of a rheumatic affection; as the disease advances, the pain is much increased by standing or walking, and the move- ments of the joint become gradually more and more impaired. The patient experiences the greatest difficulty in bending the body forwards from the hips; he consequently is unable to stoop, or to sit in the ordinary position, being obliged to keep the limb straightened in nearly a direct line with the trunk. The difficulty in walking, in standing erect, in stooping, and in sitting increase. The limb becomes shortened to the extent of about an inch or more, owing to changes that take place in the head of the bone. The pelvis also assumes an oblique direction, and hence the apparent shortening becomes considerably greater. The knee and foot are everted, and the heel raised. The shape of the hip also alters considerably; it becomes flattened posteriorly, the folds of the nates disappear, but the trochanter seems to project, and on examination seems larger and thicker than natural. On rotating the limb it will be felt that the movements of the bone are extremely limited, and crackling or osseous crepi- tation will often be felt around the joint. As Mr. Smith remarks, the lumbar vertebrae acquire great mobility, the thigh on the affected side is wasted, but the calf retains its natural size and firmness. 660 DISEASES OF THE HIP-JOINT. On examination after death, it will be found that the joint, the bones, and the surrounding parts have undergone remarkable changes. The capsular ligament is thickened, and the synovial membrane is of a bright red color, vascular, and fringed in some parts, whilst it has disappeared in others. The ligamentum teres is destroyed, and the head of the bone denuded of membrane, the vascular fringes being attached around the neck. The head of the bone becomes remarkably altered in shape, being flattened, greatly increased in size, or placed more or less at a right angle with the shaft, sometimes elongated, and always very irregular and tuberous. The neck is more or less absorbed, and in some cases appears as if it had undergone fracture. The acetabulum generally becomes enlarged, sometimes of a more or less circular and flattened shape; at others, projecting at its rim, narrowed, and embracing tightly the head of the femur (fig. 236). Both it and the upper part of the thigh-bone become porous, and perforated with numerous small foramina. Stalactitical masses of bone and porcellanous deposits are commonly thrown out about the base of the trochanter, but more particularly along the intertrochanteric line within the capsule of the joint, and not unfrequently in the soft tissues around it. In many cases the apparent increase in the size of the head of the bone is dependent on the depo- sitions of these masses of osseous tissue upon it, rather than on any expansion or osteoporosis of the upper articular end of the femur. These masses of bone constitute one of the most important characters of the disease, and it is their presence that communicates the peculiar crackling that is felt in the hip during life. The muscles and soft structures in the vicinity of the joint are necessarily wasted, partly from disuse and partly from the pressure of the morbid masses of bone. This disease most frequently occurs amongst the poorer classes, and is almost invariably met with in males. It usually occurs about the age of fifty, though sometimes earlier. I have seen two instances of it in individuals little more than thirty years of age, one of whom was a female. It is an incurable affec- tion, and, as it is commonly attended by much suffering, constitutes a source of great discomfort to the patient. It occasionally happens that individuals laboring under this affection, meeting with a fall or contusion on the hip, present many of the signs of fracture of the neck of the thigh-bone, such as shortening, eversion, with some crepitation perhaps, and inability to move the limb. The diagnosis may in general readily be effected by attention to the history of the case, and by eliciting the fact that the symptoms have existed to some degree before the accident, although the pain and immobility may have been increased by it. In the treatment of this affection little can be done. Rest and the habitual application of warm or stimulating plasters will afford relief, and, in many instances, the administration of the iodide of potass with sarsaparilla will lessen the nocturnal pain. Mr. Smith recommends an electuary composed of guaiacum, sulphur, tbe bitartrate and carbonate of potass, and ginger, with a small quantity of rhubarb, and I have certainly seen benefit result from the administration of this remedy in some cases. When the disease is once fairly established, and has assumed a very chronic character, nothing can be done except to mitigate the pain by some such means as those recommended, conjoined with rest and careful attention to the general health. Chronic rheumatic arthritis has also been described by Mr. Smith as occasion- ally affecting the temporo-maxillary articulation in individuals of rather ad- vanced life. This disease is mostly symmetrical, and gives rise to an enlarge- ment of the condyle of the jaw, which can be felt under the zygoma, attended with much pain in opening the mouth, a sensation of cracking or grating in the joint, and some enlargement of the lymphatic glands by the side of the neck. The pain is generally increased at night, and influenced by the state of the weather. The face becomes distorted, the affected side of the jaw projecting DISEASES OF THE BURSJE. 661 and being pushed towards the opposite side, but when both joints are affected the chin projects, the entire jaw being drawn forwards. This distortion is chiefly owing to the destruction of the articular eminence; for when this takes place, the external pterygoid muscle draws the jaw forwards and to the opposite side; but when both articulations are equally affected, these muscles displace it directly forwards; the glenoid cavity becomes enlarged, the fibro-cartilage disappears, and the condyle is sometimes greatly thickened and flattened, and always rough, being devoid of cartilage. In such cases as these there is little to be done by medicine, but the treatment must be conducted on the same principles as in the same affection when attacking the hip. When affecting the shoulder, chronic rheumatic arthritis gives rise to con- siderable enlargement of the head of the humerus, wasting and rigidity of the deltoid, and inability to move the elbows upwards, except by the rotation of the scapula on the trunk. In fact, the scapulo-humeral articulation being fixed, all movements of the shoulder are effected through the medium of the scapula, which becomes more mobile than natural. The articulation is the seat of much pain, lancinating at times, but generally gnawing and intermittent, being de- pendent on the state of the weather, and greatly increased in cold and wet seasons. The whole of the arm becomes wasted and weakened in power. In two instances 1 have seen this disease in young and otherwise robust and healthy men, between twenty and thirty years of age, coming on without any apparent cause. In both cases the joint continued permanently rigid, though the pain was relieved by the use of the iodides and local counter-irritation. CHAPTER XLVII. DISEASES OF THE APPENDAGES OF THE JOINTS. DISEASES OF THE BURSAE. The bursae which naturally exist, either under the skin, beneath the muscles and ligaments, or around tendons, are subject to various diseases. Not only do the normal bursae become affected, but these sacs are sometimes developed from continued friction in situations where they are not naturally met with, and here also they may undergo disease; thus, for instance, bursae have been found to be formed at the projecting point of a hump-back, on the prominent parts of club-feet, or at the extremity of stumps. In the following situations bursae naturally occur, and may consequently be expected to be met with in a diseased state. Behind the angle of the lower jaw, on the symphysis of the chin, on the angle of the thyroid cartilage, on the acromion, external and internal condyles of the humerus, olecranon, styloid pro- cesses of the ulna and radius; on the dorsal surface of the metacarpophalangeal articulations, as well as on their palmar surfaces, and on the dorsal aspect of the phalangeal articulations; on the anterior superior spine of the ilium, the great trochanter, the tuberosity of the ischium, the lower superior and outer parts of the patella, on each condyle of the femur, the tuberosity of the tibia, the two malleoli, the calcaneum, the dorsal aspect of the toes, and on the plantar aspect of the heads of the first and fifth metatarsal bones. Besides these situations they occur under the deltoid, the gluteus maximus, between the lower end of the scapula and the latissimus dorsi, and in the ham. 662 DISEASES OF THE BURSiE. The continued irritation of bursae by the pressure that is exercised upon them, may cause them to inflame, to enlarge, to become thickened, or to undergo various changes in structure. This enlargement of the bursae in particular situations is often connected with special employments, by which continuous and severe pressure is exercised upon certain parts of the body; thus frequent kneeling will occasion enlargement of the bursa patellae, hence called " house- maid's knee." Miners are occasionally subject to an enlargement of the bursa lying over the olecranon, hence called " miner's elbow," and in any situation a new bursa may be formed by continuous pressure and friction conjoined. The contents of enlarged bursae vary greatly; they may be composed simply of a serous fluid of a clear straw color; at other times this becomes dark and brownish, with much cholesterine intermixed, and may contain a number of whitish bodies, of a fibrinous or cartilaginous appearance, about the size of grains of rice and not unlike them. On examination under the microscope, I have found these granular bodies composed of a fibro-plastic material, in some cases resembling imperfectly-developed granulation cells ; they would therefore appear to consist, as Sir B. Brodie long ago pointed out, of masses of lymph that have either been deposited in the shape in which they are found, or that have been divided and broken down, after being originally formed in larger masses. The wall of the enlarged bursa is sometimes thin, at others greatly thickened by the deposit of concentric layers of plastic material within it. In some cases the deposit of plastic matter may go on into the interior of the bursae, until their walls assume a very great thickness, and almost a cartilaginous hardness, and indeed may continue to increase until the cavity is completely obliterated, and a dense fibrous tumor formed in its place. Enlarged burse are readily recognized; forming, whilst their contents are thin and serous, indolent oval tumors with distinct fluctuation; commonly occurring in the situation of some of the normal bursae. As they become more solid they become elastic and hard, and often crackle on being pressed when they contain the rice-shaped bodies; but at last acquire all the characters of an ordinary solid growth, as the deposition within them increases. Not un- frequently these enlarged bursae inflame; or, indeed, an attack of inflammation in them may be the first cause of their enlargement. In either case they become hot and tense, the skin covering them is red, often doughy, and cedematous; and although there is no connection between the bursa and the neighboring joint, yet it may happen that the inflammatory action spreads to the latter, from simple continuity of tissue. Suppuration very frequently occurs in an inflamed bursa; the tension increases, the oedema and redness become more considerable, and tbe pain assumes a throbbing character. When the bursa is opened, thick pus often mixed with shreds of sloughy tissue is evacuated. The treatment of these bursal tumors must depend entirely upon their nature and actual condition. When inflamed,—rest, the application of leeches, followed by tepid lead-lotions or poultices, and general antiphlogistic treatment will com- monly subdue the increased action in them. If suppuration take place, they must be freely opened and the pus evacuated. When in an indolent condition, the surgeon has the choice of various plans of treatment, conducted on different principles. If the sac be thin, the fluid of a serous character, and the disease recent, it may often be removed by blistering, more particularly when it occurs in the ham or under the deltoid muscle. In some cases it may conveniently be obliterated by puncturing the cyst and then employing pressure upon it. The surest mode, however, of closing the sac consists in exciting inflammation in it, either by the injection of the tincture of iodine as recommended by Velpeau, or by passing a small seton through it. The injection is readily effected by tapping the cyst with a moderate-sized trochar and then throwing in about 3J of the compound tincture. Inflammation will be excited, some discharge will usually take place, and on its cessation the walls of the cyst will have become aggluti- TREATMENT OF ENLARGED BURSuE. 663 Fig. 244. nated together. In these cases I generally prefer, however, as the most certain method, the introduction of a seton composed of a double silk thread. This may conveniently be passed through the canula after tapping the sac, in the way figured in page 348; a poultice should afterwards be applied, and the threads left in for about six days. Discharge will take place through the aperture by which they have been introduced, and which may, if necessary, be enlarged; the cyst gradually contracts around them, and after their removal it will be found to be closed. When the cyst contains a number of the rice-like bodies, the seton may still be used, but it should be thicker than that just recommended, and the aperture by which it is introduced should be very free in order to admit of the escape of the pus and granules. If the walls of the cyst are very thick, or its contents semi-solid, or if the tumor have become solid, it must be dissected out. This operation is most commonly required for solid bursal tumors, situated over the patella or the tuberosities of the ischium; from both of these situations they may be removed with facility. In dissecting out these solid bursae, an operation by the way which is occasionally required on both knees, care should be taken not to make the incisions too wide of the disease; and more especially, to avoid separating the attachments of the fascia of the limb from the edge of the patella, otherwise the layer of cellular tissue leading into the popliteal space will be opened up, and deep infiltration and abscess of the limb, sometimes even of a dangerous character, may result. Enlarged bursae, especially those situated over the patella, not unfrequently inflame and suppurate; under such circumstances a free incision should be made through their wall and the contents mixed with pus let out. When the bursa that lies towards the plantar surface of the head of the metatarsal bone of the great toe becomes enlarged, or when a new serous sac is formed upon the inner and posterior aspect of this bone, the disease termed a bunion occurs. In this affection the enlargement of the bursae is usually secondary to an alteration in the shape and position of the great toe, which, in consequence of the pressure of narrow, pointed boots, has been thrown outwards in an oblique direction, so as to lie over, or under, some of the contiguous digits (fig. 244) ; in this way a sharp angle is formed at the junction between the first phalanx and the metatarsal bone of the great toe. This angle being constantly pressed upon by the boot, becomes irritated, and, for its protection, the bursa that is there naturally situated becomes enlarged, or an adventitious one forms. From time to time the bursa and the projecting angle become irritated and inflamed, and the morbid action thus set up may run on to suppu- ration of a very troublesome kind, a thin, unhealthy pus being formed, which is discharged through an opening that speedily becomes fistulous, and may degenerate into a most troublesome, indolent sore. In the treatment of this affection, the first thing to be done is to change the direction of the toe, by wearing properly-shaped boots. The faulty position, which appears to be the primary cause of the affection, may perhaps be more effectually remedied in some cases, by the division of the external lateral ligament of the metacarpo-phalangeal articulation, or of the tendon of the adductor pollicis, or the inner head of the flexor brevis pollicis; the toe, when restored to its position, being for a time kept fixed upon an under-splint. Pressure upon the bunion may at the same time be prevented, by wearing oyer it a piece of amadou spread with soap plaster, and perforated in the centre with an aperture corresponding to the size of the tumor. If accidental inflammation 664 DISEASES OF THE BURSJE. be excited in the part, it must be allayed by the application of leeches, warm foot-baths, and poulticing; the cutaneous irritation that is left may best be removed by painting the surface with a strong solution of nitrate of silver. GANGLION. Two distinct kinds of ganglion are met with: the simple, situated upon the sheaths of tendons, and the compound, consisting in a dilatation of the sheath itself. The simple ganglia consists of cysts, varying in size from a cherry- stone to a large marble, and containing a clear transparent fluid of a yellowish color, which is sometimes thin and serous, at others, gelatinous and semi- coagulated. They occur as a smooth, globular, elastic, and tense tumor, usually situated on the back of the wrist, where it forms a distinct round projection • they may also occur on the dorsum of the foot. In both situations, they are distinctly connected with the sheaths of the extensor tendons, and, indeed Paget looks upon them as being cystic transformations of the fringe-like processes of synovial membrane lining the sheaths of the tendons. As they increase in size, they often give rise to painful sensations in the parts below them, by pressing upon neighboring nerves; thus, a ganglion at the back of the wrist often produces pain and weakness in the hand, by compressing some of the branches of the musculo-spiral nerve that are stretched over it. The compound ganglia are chiefly met with in the palm of the hand, and the dorsum, sole, or inner side of the foot. They consist of a dilatation of the sheaths of the tendons in these situations, and may often attain a very con- siderable bulk, and then usually become irregular in shape, owing to several tendons being implicated by them. Often in this form of ganglion, the sheath is simply thickened as well as dilated, and the contained fluid is clear and yellowish, though usually thinner than in the simple ganglion. The sheath itself is vascular, and lined by a red, fringed, and velvety membrane; the fluid may then be dark and bloody, and contain masses of buff-colored fibrine or a large number of granular bodies, like those met with in certain forms of enlarged bursae. These I have found to be composed of imperfectly-developed granulations, in which the remains of blood-vessels were visible, probably thrown off from the inner wall of the vascular sheath. This form of the disease, at times, puts on almost a malignant appearance, is extremely chronic in its char- acters, and may occupy a very extensive surface; in a case of the kind that was under my care, some time ago, the dorsum and greater part of the inner side of the foot were involved. The treatment of these diseases must depend upon their character and size. When small and simple, as on the back of the wrist, they may commonly be got rid of by being ruptured by forcible pressure with the thumb, or by a blow with the back of a book, or by being tightly compressed, by means of a six- pence wrapped in a piece of lint, and firmly strapped upon the swelling. If they do not disappear in this way, the better plan is to puncture them by means of a valvular opening, to squeeze out their contents, and then to employ pres- sure. If they give rise to much pain and weakness, and do not disappear by the means indicated, they may be dissected out, if it be thought advisable to have recourse to this somewhat severe procedure, which is not altogether unat- tended with the risk of inflammation extending up the sheath of the tendon. I have, however, on several occasions done it, without any troublesome consequences ensuing. A ganglion situated in the palm of the hand, and extending under the annular ligament some little distance up the flexor tendons of the fore-arm, is a very troublesome disease. Mr. Syme recommends that the cyst should be laid open, and the annular ligament divided. This seems to me an unneces- sarily severe procedure, and I have in several instances cured the affection by DISEASES OF THE MUSCLES. 665 milder means; in one, by injecting a small quantity of tincture of iodine into the cyst through a puncture in the palm, and in two or three other cases by the use of the seton; and this is the plan that I should recommend for adoption. In the side or sole of the foot, these ganglionic tumors, when of large size, and filled with semi-solid fibrinous matter, may require to be dissected out. Inflammation of the sheath of the tendons — tenosynovitis — is occasionally met with as the result of strains and twists of the hand, about the wrist, of the extensor tendons, or the long head of the biceps. In this affection there is swelling of a puffy character, with tenderness upon pressing upon or moving the part; and usually a peculiar fine crackling sensation is communicated to the surgeon's hand when he examines the affected part. This crackling is especially marked in those cases in which the inflammation and effusion have become chronic, when the disease appears to partake of the nature of a diffused ganglion. The treatment, when the disease is acute, consists in leeching and blistering, with rest of the part; when it is chronic, the application of blisters and the mercury and ammoniacum plaster will be found most useful. CHAPTER, XLVIII. AFFECTIONS OF MUSCLES AND FASCIAE. Strains of muscles, especially of those of the back and loins, attended by pain, weakness, and some rigidity, are not unfrequently met with as the result of sprains or injuries of various kinds, more especially in rheumatic constitu- tions. They may be best remedied by the use of Corrigan's iron, dry cupping, stimulating embrocations, and the internal administration of colchicum or guaiacum. CONTRACTIONS AND RETRACTIONS. Under the head of muscular contractions are included various deformities, such as squint, wry-neck, club-foot, club-hand, some of which are congenital, others acquired. In all of these conditions, the deformity is primarily owing to an affection of the muscular system, and not to disease of the bones or liga- ments, which are only secondarily implicated. The causes of these deformities are very various, but they may be referred to three heads. 1st. The continuous faulty or abnormal position of a limb, as in an unreduced dislocation, or an anchylosed joint, will be followed by the disuse of a certain set of muscles, which consequently become shortened and atrophied, and acquire a rigid state. This condition is consecutive to the displacement, but renders it permanent; it is apt to occur after fractures, if the parts are kept for too long a time in one position, and more particularly if bound and matted together by the pressure of tight bandages. A somewhat similar cause sometimes operates on the foetus in utero; an abnormal position in the uterine cavity being very frequently the immediate occasion of some of the varieties of congenital club- foot. 2d. Irritation being set up in the central portions of the nervous system, may produce deformity by deranging the proper antagonistic action of certain groups of muscles. This condition gives rise to many of the congenital, as well as the 666 SPECIAL DEFORMITIES. non-congenital deformities. It may act by producing more or less complete paralysis of one set of muscles, the contractility of their antagonists continuing normal, and thus the relative balance of action being destroyed, the stronger will draw the part over to their side. The influence of this want of proper balance of parts in paralysis, producing deformity, may be well seen in palsy of the portio dura, where the face is distorted by being drawn to the sound side; or in squint, where the external rectus being paralyzed, the eye is drawn in- wards. According to Mr. Tamplin, deformity from paralysis is never congenital, though it is not unfrequently met with in the non-congenital cases. Central irritation may occasion deformity in another way, by producing tonic or perma- nent spasm of one set of muscles, the other remaining perfect in their contract- ility, but over-balanced by the continued contraction of their antagonists. This would appear to be the case in some forms of squint. 3d. Peripheral nervous irritation may occasion contraction of the muscles and deformity. This we commonly see happen in cases of contraction occurring from the irritation of worms in the intestinal canal, in the so-called hysterical contractions from uterine irritation, etc. From all these various causes contrac- tion and deformity may arise. In some cases deformity will cease after the removal of the cause; but in other instances, in which it has been of long duration, the deformity will continue, owing to the muscles having fallen into a kind of rigid atrophy, being shortened and wasted, and consequently unfitted for the proper exercise of the actions of the part. The general treatment of deformities consists in removing the cause of the contraction in those cases in which it is dependent on central, peripheral, or nervous irritation that admits of remedy. Thus, if squinting arise from pres- sure upon the brain, the eye will resume its straight direction when the con- gested vessels are relieved, or the effused fluids absorbed; or if a contraction of the ham-string muscles arise from the irritation of worms in the intestinal canal, a dose of purgative may cure the affection. When, however, the deform- ity is of a congenital or more permanent character, the employment of orthopcedic means and the division of the tendons is the only mode of restoring the natural condition of the part. This orthopoedic department of surgery owes, in a great measure, its existence to the labors of Delpech and Stromeyer, and its perfection to those of Little and Tamplin. By tenotomy, as at present practised, is meant the subcutaneous division of a tendon by means of a very narrow-bladed knife (fig. 245) introduced obliquely through a puncture by its side. In doing this, it should be borne in mind that the normal anatomical relations of parts are often a good deal disturbed in cases of deformity; and thus tendons may be approximated to arteries and nerves from which, in the healthy condition of the limb, they are widely separated. The tendon may most conveniently be divided, in the majority of cases, by introducing the blade beneath it sideways, and then turning the edge against it, scratching through it by a kind of sawing movement, whilst the parts are Fig. 245. made tense by an assistant. A drop or two of blood only are lost in this simple operation, and, as the divided tendon retracts with a kind of snap, a gap will be left between the two ends, of from half an inch to an inch in width, accord- ing to the previous amount of tension in the part. If the muscles have been contracted for some years, it will commonly be found that the fasciae in the neighborhood of the tendon have become rigid and unyielding, forming cords or bands stretching across from the side of the gap. If these are very tense, TENOTOMY. — SQUINT. 667 they may be divided in the same way; but in many instances it will be found, after a lapse of a short time, that they will yield, and consequently will not require division. After the section has been made, the small puncture should be closed with a strip of plaster or some lint soaked in collodion. The part should then be left without any apparatus being applied for three or four days. At the expiration of this time, lymph will have been thrown out, and then proper mechanical contrivances may be adjusted for gradually restoring the normal position of the limb or part; if this be done too soon, the cicatrix will be extended at too early a period after the deposit of the plastic matter, and the division will become weakened and too much elongated. The divided ten- don unites like one that has been ruptured, by plastic matter that gradually assimilates to and at last closely resembles its substance. Tamplin states that, on examining the tendo achillis of a boy who died twelve months after it had been cut across, no trace of injury could be noticed, except a slight globular appearance opposite the seat of incision. In cases of congenital malformation, the question frequently arises as to whether tenotomy should be performed in early infancy, or delayed to a more advanced age. As a general rule, I think that the sooner these operations are done the better; they are not more difficult at an early period of life than at any other, no danger attends them, and by being performed during infancy, there is a far less chance of the deformity being permanent, than if the operation is delayed for some years. SPECIAL DEFORMITIES. By squint or strabismus is meant a want of parallelism in the position and motion of the eyes. Most commonly a squint is convergent, the edge of the cornea being buried under the inner angle of the lids, more rarely the divergent form is met with. In convergent strabismus, one eye only is generally affected, but in some cases both are implicated, though one eye is almost invariably worse than the other; and this gives an appearance as if there were an alternation of squinting in the two eyes. In order to ascertain which eye squints, the simplest plan is to direct the patient to look at a distant object, when the sound eye only will be directed towards it, the affected one being turned inwards. Squint may arise from a variety of causes; it not unfrequently comes on in children after infantile complaints, such as measles or scarlatina, and as Sir C. Bell has observed, commonly depends upon weakness of the external rectus, owing to some paralytic affection of the sixth nerve, seldom upon spasm of the internal rectus. In many cases it is indicative of disease of the brain or nervous centres, occasioning paralysis or irritation of the motor nerves of the eye; in other instances it may occur from the irritation of worms in the intestinal canal, and not unfrequently is dependent upon some disease of the eyelids or eyeball. Thus'the various inflammatory affections of the conjunctiva and eyelids may occasion it; or, it may, as not unfrequently happens, when it occurs in adults, be dependent on the difference in the focal length of vision, owing to amaurosis or the failure of sight in one eye; and lastly, in children it may be induced by habit or imitation. The treatment of squint must to a certain extent be influenced by its cause. Thus the removal of congestion of the brain or the expulsion of worms from the intestines may cure the affection; or, if it have followed simple debility in children, it will disappear as their strength improves, and they will thus out- grow it. If, however, the deformity be of a permanent character, it may readily be remedied by the simple operation that was introduced by Dieffenbach. The operation for squint should not I think be performed until the child has attained its eighth or tenth year, as it is not very easy to do it satisfactorily before this period, owing to the restlessness of infants; and, in very many instances, the 668 SPECIAL DEFORMITIES. squint gradually disappears as a child grows older without any operative pro- cedure being had recourse to. Indeed, in many cases it may be better to defer it till the adult age is reached. On the other hand, it should not be delayed too long, lest some contraction of the features or deformity in the other eye be left, and thus a very satisfactory result be not obtained. The operation is suffi- ciently simple; it may most conveniently be done by bandaging the sound eye, and then directing the patient to look outwards with the affected one; a fold of the conjunctiva near the inner canthus is then seized with the forceps, and snipped transversely with a pair of rather sharp-pointed scissors. By dilating the wound slightly with the scissor blades, the tendon of the internal rectus will be exposed, which may be seized with the forceps, and readily cut across; or, a very convenient plan consists in passing a curved director underneath it, raising it upon this, and then dividing it either with the scissors or a small curved bistoury. During the operation the eyelids must be held apart by an assistant, who may if necessary use the eye speculum for this purpose. After the operation, a piece of wet lint should be laid upon the eye, and if any fungous granulations spring from the wound, they must be snipped off or touched with the nitrate of silver; some double vision may be left, but this gradually wears off. Mr. Critchett advocates the subcutaneous section of the muscle in strabis- mus, as being less likely to be followed by those inconveniences and deformities that attend its division in the ordinary way, viz., depression of the caruncle, slow healing, an unsightly cicatrix, and often more or less prominence and eversion, that are as disfiguring as the condition for which the operation is done. Wry-neck, torticollis, or Caput obstipum may arise either from spasm or from paralysis of one of the sterno-mastoid muscles, the head in the first instance being drawn to the affected side, in the second, to the opposite one. Although wry-neck is usually owing to contraction of the sterno-mastoid muscle, yet in some cases the trapezius is also at fault, more especially its anterior border and clavicular margin. It usually comes on in childhood, and not unfrequently commences with an ordinary stiff neck from cold; after existing for some time it becomes conjoined with a certain amount of twist of the cervical spine, and a tendency to lateral curvature. Besides these, which may be considered the true forms of wry-neck, deformity in this situation may occur from diseased cervical vertebrae, or from the traction of the cicatrix of a burn. These, however, are peculiar conditions depending upon causes that are irrespective of the state of the muscles, and may readily be distinguished from the true form of the disease. The treatment of torticollis arising from permanent spasm of one of the sterno- mastoids, which is the common form of the affection, may best be conducted by dividing the inferior attachment of the muscle, and thus allowing the head to regain its proper position. The division of the muscle is a somewhat delicate operation, on account of the important structures that lie immediately behind it. By making the incision, however, through it, from behind forwards, close to the sternum and along the clavicle, there can, if ordinary care is employed, be little risk of doing any damage, as these bones carry the lower attachment of the muscle forwards, and separate it from subjacent parts. The tension also into which it is thrown by its spasm draws it away from the carotid sheath. In several instances in which I have had occasion to perform this operation, no difficulty whatever has been experienced in dividing the sternal attachment of the muscle, which is usually very tense and prominent, by passing an ordinary tenotome behind the tendon, with its flat side towards it, just in front of the upper margin of the sternum, and then cutting forwards, whilst the muscle is put well upon the stretch. ^ In dividing the clavicular insertion, the safest plan I think con- sists in making a puncture with a scalpel upon and down to the clavicle in the cellular space, that lies between the two attachments of the muscle, and then pushing a long, blunt-pointed, narrow-bladed tenotome between that bone and the insertion of the muscle, dividing this in a direction forwards. After the CLUB FOOT. 669 operation the head should be drawn to the opposite side by means of proper apparatus. In this way the curvature of the cervical vertebrae may gradually be corrected; should it, however, have existed for a considerable time, it may have assumed a permanent character; and a twist in the neck will continue for life. After the division of the tendon the deep fascia of the neck will some- times be found stretching across in firm and tense bands; these, however, had better not be interfered with, as they will generally yield, and much risk of injuring the subclavian and carotid vessels would attend any attempt at their division. In those cases in which the wry-neck appears rather to be dependent upon paralysis of one sterno-mastoid, than spasm of the other, electricity, and the application of strychnine to the blistered surface over the muscle, will be found most useful. In spasm of both sterno-mastoids, the head is thrown forwards, the muscles projecting in great relief. In these cases the disease will usually be found to have had a rheumatic origin. Club-foot.—Deformities of the feet are commonly single; but not unfrequently they affect both extremities. They appear to be more frequent in boys than in girls. Four varieties of club-foot are recognized; — the talipes equineus, in which the head is elevated; the talipes calcaneus, in which the anterior part of the foot is drawn up; the talipes varus, in which the foot is twisted inwards; and the talipes valgus, in which it is twisted outwards. These conditions may occur in the simple forms just mentioned, but most commonly the varus is com- plicated with the talipes equines, and not unfrequently the valgus with the cal- caneus. Bonnet, of Lyons, has made a classification of talipes, according as it is occasioned by an affection of the internal or of the external popliteal nerve. When the muscles supplied by the internal popliteal are affected, we have the talipes equineus, equineo-varus, and varus. When the external popliteal is affected we have the calcaneus and valgus. On dissecting a foot affected by talipes, it will be seen that but little alteration has taken place in the condition of the bones. In some preparations of this kind, that are in the University College Museum, these are nearly in a normal condition (figs. 247-250). Ipdeed, in the talipes equineus and calcaneus, they are scarcely, if at all, altered, but in the varus and valgus, if of old standing, the astragalus will generally be found atrophied, more particularly about its head, which may be somewhat twisted, and the scaphoid and cuboid will be seen to have undergone similar changes. The ligaments are necessarily somewhat altered in shape, being lengthened on the convexity, and shortened on the con- cavity of the foot; the direction of the tendons is altered, and the muscles not only of the foot, but of the leg and thigh, are generally atrophied from disuse, so that the limb in old cases is withered and shortened; indeed, so great an in- cumbrance may it occasionally become under these circumstances, that amputa- tion of the leg may be insisted on by the patient, and may with propriety be performed by the surgeon. Talipes equineus is characterized by elevation of the heel, and great tension of the tendo achillis, so that the foot is extended in nearly a straight line with the leg, and the patient walks on his toes, which are placed at a right angle to the foot (figs. 246, 247). In this deformity there is no lateral displacement. According to Mr. Tamplin it is never congenital. It most commonly arises from disturbance of the nervous system, during teething, or from the irritation of worms in children. In adults it may come on from some disease, such as abscess in the calf of the leg, by which the gastrocnemius muscle is crippled. It is the most important of all the forms of club-foot, as it commonly com- plicates the other species. The treatment consists in dividing the tendo achillis, and bringing the heel well down. The tendo achillis is best divided about an inch above its insertion into the os calcis. The patient should be laid prone, and the surgeon grasping the foot 670 SPECIAL DEFORMITIES. extends it forcibly, so as to throw out the tendon in good relief, and make it tense; he then slides a tenotome beneath it, and cuts slowly through it from Fig. 247. beneath upwards, bearing well upon the foot; as the division proceeds, he will hear the tendon cracking as its fibres are successively cut through. The division snould never be made from above downwards, as the posterior tibial artery or its malleolar branches might readily be wounded. The talipes calcaneus is an extremely rare variety of club- foot. In it the heel is de- pressed, the toes and anterier part of the foot being ele- vated (fig. 248) ; it is always, I believe, congenital, and arises from contraction of the extensor tendon. In order to bring down the foot, the tibialis anticus, the extensor communis, the extensor pollicis, and the peroneus tertius, may all require to be divided as they pass over the dorsum; a straight splint should then be applied, and the foot drawn down to it. A minor degree of this affection consists in a peculiar projection upwards of one or two of the toes associated Fig. 248. with some tension of the extensor ten- don ; by dividing this, and keeping the foot on a flat splint, this deformity may commonly be corrected. In some cases, however, the toe is so promi- nent, and the contiguous ones are squeezed under it in such a manner, that the foot is completely crippled, and amputation of the displaced digit is required in order to restore the utility of the member. Talipes varus. — In this deformity the foot is twisted inwards, and the sole is contracted, the patient walking side of the foot, where the skin covering the tarsal end metatarsal bone often become excessively dense and firm, occasionally forms (figs. 249, 250). In most cases there is some elevation of the heel, the affection partaking somewhat of the equineus character. It is the most common form of congenital deformity, both feet being found similarly affected; but it may be non-congenital, and then it is limited to one. The treatment consists in the division of the tendo achillis, together with the tendons of the tibialis anticus and posticus, which are the muscles principally at fault. In most cases the plantar fascia is contracted, and requires division wherever it feels tense and projecting. In the section of the tibialis posticus tendon in the sole of the foot there is much danger of wounding the posterior tibial artery, which lies close to it. The best way to avoid this vessel is to puncture the sheath of the tendon with a sharp scalpel introduced directly downwards, and then to divide it in a direction forwards, away from the vessel, with a blunt tenotome. There will also be less risk of this accident on the outer of the fifth and a bursa CLUB-FOOT. 671 occurring if the tendo achillis be divided first, so that the others may be ren- dered more tense, before their section is undertaken. But in cutting through Fig. 249. Fig. 250. the tendo achillis there is also some risk of wounding the artery, as in bad cases of varus these two structures lie nearly parallel to one another, the tendo achillis being drawn out of the median line towards the inner ankle. Indeed, in one instance, I have seen the posterior tibial artery punctured during the division of this tendon, or rather in an attempt to divide some tense bands that lay be- neath it; the bleeding, which was very free and in a full jet, was, however, readily stopped by pressure, no bad consequences resulting. The proper plan of treatment, when such an accident occurs, is, when the artery is merely punc- tured, to cut it completely across, and then to apply firm pressure, by means of a pad and bandage, over the bleeding orifice. Mr. Tamplin states that he has seen no ill effects follow this accident. If a circumscribed false aneurism has formed, it must be laid open, the clots turned out, and the vessel tied. No ex- tension of the foot should be practised for some time in such cases, lest the coagulum be disturbed. In ordinary cases of varus, after a lapse of four or five days, Scarpa's or Lit- tle's shoe, or Aveling's Talivert may be applied; or the foot be well abducted by means of a wooden splint, fixed to the outer side of the leg, and provided with pegs, so placed that the toes can be drawn up, and the foot well turned out by rollers and tapes attached to them. Talipes valgus —flat or splayfoot — is the anti- Fig. 251. thesis to varus. In it there is a tendency in the first instance to the obliteration of the arch of the instep, so that the sole becomes perfectly flattened; and as the disease advances, a tendency to eversion of the foot usually takes place (fig. 251). When it has advanced to this extent the toes and anterior part are often somewhat raised, so as to constitute the variety termed calcaneo-valgus. In this kind of deformity the ligaments of the sole of the foot, which bind the bones together so as to form the arch, are weakened and elongated, and the pero- neal and extensor tendons commonly tense. It is not so frequent a form of club-foot as the other varieties, and commonly affects only one extremity. When both feet are everted there is usually knock- knee as well. The treatment consists in the division of the tendons of the pero- neus longus, and brevis, behind the outer ankle; and of that of the extensor 672 SPECIAL DEFORMITIES. communis on the dorsum. Scarpa's shoe may then be applied, and the arch of the foot restored by wearing a pad under the sole for some considerable time. The talipes calcaneo-valgus is not a congenital affection; and as it commonly arises from a partially paralyzed state of the gastrocnemius, the treatment is not very satisfactory. In talipes calcaneo-valgus the projection of the heel backwards is obliterated, and the outer side of the foot curved round towards this, so that the little toe approaches the point of the heel. Weak ankles not uncommonly occur in ricketty children ; the ligaments being relaxed, the joints appearing to be swollen, and the child unable to walk or stand without great difficulty. Under these circumstances, attention to the state of the general health, douching with salt-water, the application of an elastic India-rubber bandage round the ankle, or the use of light iron supports, will be found most useful. The deformity termed genu-valgum, knock or X knee, usually affects both extremities, though it is generally more fully developed in one than the other. In it the knee forms the apex of a triangle, the base of which would be repre- sented by a line drawn from the trochanter to the outer ankle. It is usually conjoined with some curvature of the bones of the leg. It is not a congenital affection, but commonly occurs in consequence of children being put upon their feet too early, the limbs thus giving way under the weight of the body. Brock states that out of 221 cases that he examined, 17 originated about the period of the first dentition; and about 200 between that age and the 15th or 18th year. Some occupations are said to predispose to it, smiths being especially liable to the disease. In it there is relaxation of the internal lateral ligament; the biceps, the external lateral ligament, and often the vastus externus are very tense; and the patella thrown outwards. The external condyle of the femur will generally be found to be small and the hollow of the ham to be obliterated. The treatment consists, in the slighter cases, in applying a well-padded splint along the outside of the leg and thigh; this must extend from the trochanter to the outer ankle, being fixed to a pelvic band at the upper part, and into a boot below. Where it corresponds to the knee it should be provided with a hinge, and should have a broad well-padded strap passing from its under side, over the inner side of the knee, and attached by buckles to the upper part of the splint, in such a way that by tightening these the knee may be drawn out- wards. This apparatus should be constantly worn for many months, and if pro- perly adapted may effect a cure. When the deformity is of old standing, and the parts about the outer side of the joint very tense, the biceps tendon may require division. In doing this care must be taken not to injure the peroneal nerve. In some cases the vastus externus and contiguous portion of the fascia lata may also be advantageously divided, and the padded splint then applied as directed. CONTRACTIONS OF THE KNEE-JOINT. Contraction of the knee-joint is one of the most distressing deformities to which the human frame is liable. If severe, the leg is bent at nearly, or per- haps at quite, a right angle with the thigh. It is fixed in this position, so that the patient cannot put the sole of the foot, or even the points of the toes, to the ground; hence the limb becomes useless for the purpose of progression, and, from want of exercise, atrophies. But a leg with a badly-contracted knee is worse than useless — it is a positive incumbrance; for, as the foot cannot be brought fairly to the ground, the limb projects behind in a most awkward manner, swaying as the body moves round, constantly in the way, and liable to injury. From want of exercise, the nutrition of the limb thus affected becomes CONTRACTIONS OF THE KNEE-JOINT. 673 impaired; the foot is usually habitually cold, the circulation in it languid, and the toes become liable to chilblains and troublesome ulceration. In the less severe form of contracted knee, the inconvenience, though not so great as that just described, is yet very considerable; for, as the patient can never bring the heel or sole to the ground, he rests insecurely on the tips of his toes, and walks but unsteadily with the aid of a crutch or stick. This deformity may be of two kinds — 1st, it may consist of simple flexion of the leg on the thigh, at a greater or less angle, and with more or less mobility, according to the degree of anchylosis; 2d, in addition to this, there may be horizontal displacement of the bones, the head of the tibia being thrown backwards, the femur and patella remaining in situ, but apparently projecting more than is natural. In examining a case of contraction of the knee-joint, the patient should be placed on his face, with the thigh extended. The leg on the affected side will then be raised more or less perpendicularly, and the amount of contraction may be judged of by the angle that it forms with the thigh. The degree of mobility also may readily be ascertained. In this way a more correct idea of the amount of contraction can be obtained than by examining the patient whilst lying on the back, when, in consequence of the thigh being flexed on the abdomen, the extent of the angular deformity cannot be so well determined. Contraction of the knee-joint may arise from a great variety of pathological conditions. Some of these are altogether external to the joint, being seated in the nerves or muscles of the limb; whilst others, and the majority, are dependent on some morbid change that has taken place within the joint itself in its liga- mentous or osseous structures. As the contraction depends on such very varied causes, the treatment, having reference to the cause as well as to the actual morbid conditions, must be equally diversified. Contraction from nervous irritation is usually associated with general hysteria, of which it is but a local symptom, and commonly occurs in girls and young women. In this form of contraction there is no evidence of disease within the joint; no redness, swelling, or other sign of inflammation; but there is great pain and tenderness about it. This pain, as usual in hysterical cases, is super- ficial and cutaneous, and radiates to some distance beyond the articulation. Any attempt at straightening the limb not only greatly increases the pain, but also calls the muscles about it into such forcible action that it is impossible to improve its position. These local symptoms are connected with the ordinary signs of an hysterical temperament, with spinal irritation, and often with uterine derangement. ... The treatment of these cases of hysterical contraction of the knee is simple. The first thing to be done is to straighten the limb. This can only be effected by putting the patient under the influence of chloroform, when, all sensibility being suspended, the muscular opposition, which is partly voluntary, and no doubt in some measure reflex, is no longer called into action, and the limb falls of its own accord almost into the straight position, in which it must be retained by means of a long splint, lest the retraction recurs with returning conscious- ness; and then, the hysterical condition being removed by treatment calculated to improve the general health, the tendency to the return of the deformity will be obviated. . „ , We occasionally see contraction of the knee from spasmodic action ot the hamstrings, arising from some irritation applied to the nerves at a distance from the°part. Just as we have spasm of the internal rectus of the eye occa- sioning squint, so long as the irritation that gives rise to the spasm lasts; so we may have spasm of the hamstrings, with contraction of the knee as a C°Most commonly, however, the joint itself is at fault, owing either to inflam- 43 674 SPECIAL DEFORMITIES. matory action of a subacute character going on within it, or to the chronic and permanent changes induced by former inflammatory attacks. In inflammation of the knee, the patient naturally and instinctively places the limb in the semi-flexed position, as being that in which there is least ten- sion exercised on the structures that enter into the joint, and consequently that which is most congenial to his feelings. This position, which is immediately assumed on the occurrence of acute and active inflammation in the joint, comes on more gradually in cases of subacute inflammation, and here the symptoms of disease in the joint may be so slight that the contraction may be considered the chief ailment, and engross too exclusively the surgeon's attention. The next class of cases that we have to consider are those of a more chronic and intractable kind, lasting often for years, dependent upon structural lesions of a deep and important character in and around the joint, and requiring very active surgical interference for their cure. These chronic forms of contracted knee appear to arrange themselves in four distinct varieties, being dependent— 1st, on consolidation and contraction of the ligamentous structures in or around the joint; 2d, on permanent contraction of the muscles; 3d, on both these con- ditions conjoined; and 4th, on osseous anchylosis. Each of these varieties will require separate consideration, as each demands a special mode of treatment for its cure. Those cases of contraction of the knee that depend on consolidation of the ligamentous structures in and around the joint, resulting from former inflam- matory attacks, are not only the most numerous, but the most readily amenable to treatment. In these cases the knee is usually fixed at, or near, a right angle, and admits of but very limited motion, to such a degree only, in most instances, as will allow the foot to move to the extent of two or three inches. _ The ham- string muscles are not tense, even when the knee is extended to its utmost; and, indeed, in some cases are flaccid, and feel soft. Not unfrequently the leg admits of extension up to a certain point, with as much freedom as natural, and then the further movement of the limb is checked by a sudden stop. If this be not dependent on the tibia coming in contact with an anchylosed patella, it is owing to shortening of the crucial ligaments, or to the formation of adhesions within the joint. In this form of contraction, the knee is often much distorted, owing to the head of the tibia being partially dislocated backwards, or having its axis directed more or less to one side, most commonly inwards, constituting a kind of genu valgum. These distortions are, I believe, dependent on soften- ing and consequent relaxation either of the ligamentum patellae, or of one or other of the lateral ligaments. When the head of the tibia is displaced back- wards, it will most generally be found that the ligamentum patellae has been either partially absorbed, and thus weakened, or is elongated, the patella being drawn upwards or to one side. Fig. 252. In either way the action of the extensor muscles of the thigh upon the head of the tibia is weakened, and that bone being consequently brought under the influence of the hamstrings, with- out a counterpoise, is drawn back- wards (fig. 252). In those cases in which there is lateral rotation of the tibia, the faulty position may have arisen from the attitude that the limb has been allowed to as- sume during the progress of the disease in the joint. In the treatment of this form of contraction of the knee, simple extension of the limb will often prove sum- CONTRACTIONS OF THE KNEE-JOINT. 675 cient. This may either be done gradually by means of the screw splint behind the knee, or forcibly and at once under the influence of chloroform. I prefer the latter method, not only as being the speediest, but as being perfectly safe and effectual. The mode of effecting forcible extension is as follows : — The patient being fully under the influence of chloroform, and lying on his face, the surgeon, standing above him, seizes the foot of the affected limb with one hand, whilst with the other he steadies the limb just above the knee. He now extends the limb gradually but forcibly; as it comes forwards the bands of ad- hesion in and around the joint will be felt and heard to give way with loud snaps and cracks, distinctly audible at some distance. Should there be much resistance within the joint, the surgeon may apply his own knee or elbow to the upper surface, and thus increase the force with which the limb is acted upon. In this way I have never found any contractions of the kind now under con- sideration able to resist the surgeon's efforts, or any difficulty in effecting at once the extension of the limb. Nor have I ever seen any evil consequences result; indeed, it is surprising what an amount of force a joint that has been contracted for any length of time may be subjected to without inconvenience. In these cases it would appear as if the synovial membrane lost its suscepti- bility to inflame, just as we find is the case with serous membranes that have been the seat of chronic inflammation and its consequences. Beyond some pain for a few days, and slight heat, easily subdued by cold evaporating lotions, I have never seen any ill results arise; but then care must be taken that no in- flammatory action is going on within the joint at the time of this manipulation, as it certainly would be followed by injurious results. After the extension has been made, the limb should be fixed on a long splint, well padded, some eva- porating lotions applied, and the patient kept in bed for a few days, when, with the aid of a starch bandage, he may Fig. 253. walk about. After extensio.. has been effected, the position of the \ head of the tibia backwards may still occasion considerable \ deformity and weakness of the limb (fig. 253). This con- '. dition is best removed by the use of the instrument of which the following sketch (fig. 254) is a good representa- tion, and was designed and constructed by that excellent surgical mechanician, Mr. Bigg. The diagram (fig. 253) represents the limb of a patient whose tibia has become displaced backwards, the angular contraction having been remedied. In the centre of the end of the femur and the head of the tibia, two letters (X and Z) are placed to de- signate the axis of each bony head, beneath and above which the displaced joint has formed its abnormal axis. The dotted lines represent the leverage formed by the cylindrical surface of the tibia and femur. The arrows are placed in such a direction as the bones would take in resuming their normal position. It will readily be seen that any instrument capable of acting in the mechanical directions shown by the arrows, would accomplish not only the restoration of the joint, but extend, if contracted, the extremities of both femur and tibia. Fi"\ 254 shows the application of the instrument by which this can be effected. An additional advantage that this instrument possesses over any other with which I am acquainted, is the appli- cation of spring power, by means of which flexion of the knee becomes an element towards its restoration. 676 SPECIAL DEFORMITIES. Instead of arresting muscular action, and thus giving rise to atrophy of the limb, movement is conducive to the perfect action of the apparatus, so that the patient experiences but little inconvenience from its use, all the ordinary positions assumed by the knee in walking, sitting, or standing, being preserved. By this form of apparatus, then, three important points are secured, viz.: replacement of the head of the tibia; extension Fig. 254. of the angle of the leg; and free muscular action during the period of treatment. Fig. 254. A and B are three levers, composed of metal, corresponding in their direction to the perpendicular position of the femur and tibia. C and D are two axes, placed exactly coincident with the centres of the articular ends of the bones. E and F are two powerful springs, whose action takes place in opposing directions, similar to the arrow-indicators in fig. 253. Thus F presses the lever B in an anterior direction, bearing the end of the tibia forward, whilst E presses the lever A in a pos- terior direction, bearing the end of the femur backward. As C and D are found acting above and below the actual axis of the knee- joint, they mutually influence the point formed by the apposition of the heads of the tibia and femur; and as it has already been explained that the femur really offers a fixed resistance, and the tibia moves beneath it, the head of the latter bone is turned anteriorly in a semi-circu- lar direction consequent on the upper centre (C) being a fixed point, and the lower centre (D) rotating around it. G is an elastic knee-cap; H, a padded plate. When the ligaments are tense, there is a chance of pressing the anterior surface of the tibia against the posterior surface of the femur. This is readily obviated by having the shaft (A) made to elongate, when the centre (C) being a little lowered, pushes the lever (B) down- wards, carrying the tibia with it and thus separating the osseous surfaces of the joint. The next class of cases of contracted knee that we have to consider are those in which the hamstrings are at fault, either alone or in addition to those results of chronic inflammatory action within the joint that we have just been describing. In these cases the hamstrings will be found to be tight, and in proportion as the leg is extended on the thigh, they will become tender, until at last all further extension is resisted, apparently by their traction, and not by any sudden check or stop within the joint itself. Of the division of the hamstring tendons I need say little. It is as simple an operation as any in surgery, unattended by any difficulty or danger, provided the surgeon introduces the tenotome parallel and close to the side of the tendon to be divided, and cut in a direction from the inside or popliteal aspect towards the skin. After the division of the tendons, it not unfrequently happens that tense aponeurotic bands will be found to stretch along either side, or perhaps down the centre of the popliteal space. This may lead to the erroneous idea on the part of the surgeon that he has not fairly cut the tendons across; but this is an error. The bands alluded to are condensed, sharp-edged prolongations of the fascia lata, formed during the period of contraction of the joint by the DEFORMITIES OF THE ARM AND HAND. 677 retraction and thickening of this membranous expansion. Such condensations as these had better be left untouched, as they will readily stretch out under gradual extension, or be ruptured by forcible traction of the limb. If, on the other hand, the surgeon be tempted by their apparently superficial and safe position to proceed to their division, he may be led into a serious dilemma by being brought more readily in contact with the popliteal vessels than is desirable or safe. In these cases the anatomical relations of parts are so much altered by the narrowing of the popliteal space, and by the projection of the head of the tibia backwards or by its lateral rotation, that the surgeon is unable to calculate with sufficient nicety the precise position of the large vessels and nerves in the neighborhood of which he is about to act, and he might thus injure one or other of these at a time that he thought he was operating at a safe distance from them. After the division of the hamstrings, the knee does not commonly come readily into the straight position, but forcible extension will be required to break through the adhesions within and around the joint. This may be done at once without inconvenient results, or it may be deferred for a week if the surgeon thinks better to delay extension after tenotomy. Osseous anchylosis of the knee is not of very frequent occurence. The only remedy in such cases would be the operation practised by Dr. Rhea Barton,— of sawing out a wedge-shaped portion of the anchylosed bones, and then bring- ing the limb into the straight position. Judging by the excellent results that have followed resections of the knee-joint, such an operation is not unlikely to be attended by good success. Should there be much atrophy of the limb with shortening of it, and possibly necrosed bone with old sinuses and occasional abscesses about the knee, amputation will place the patient in the condition of most comfort. DEFORMITIES OF THE ARM AND HAND. Contractions of the arm are not of very frequent occurrence, except as the result of burns. I have however met with three distinct forms of contraction of the fore-arm: — 1st. The case in which there is anchylosis of the elbow- joint, the fore-arm being bent usually at a right angle with the arm, the result of chronic disease of the articulation. Here, if the anchylosis be incomplete, a very useful limb may be restored by breaking down adhesions under chloroform by forcible flexion and extension, and then using passive motion, friction, and douches. If the anchylosis be complete, the bones should be resected, and a false joint allowed to form. 2d. The biceps may by its contraction occasion a permanent flexion of the arm. In such cases division of the tendon may be practised, due care being taken of the artery and nerve. This operation is most safely done by introducing the tenotome to the inner side of the tendon, slipping it under, and cutting upwards and outwards, the artery being guarded and pushed to the inner side by the pressure of the left forefinger. 3d. The fore-arm may be forcibly pronated and flexed as the result of chronic inflamma- tion of the radio-humeral articulation. Here forcible supination and extension under chloroform is the best remedy. A deformity resembling club-foot has occasionally, though very rarely, been met with in the hand. The contraction may occur in two directions; either in the sense of preternatural flexion, or in that of abnormal extension of the member. It is always congenital, and has been principally described by Cruveilhier, Voillermier, and Smith of Dublin. In most of the cases that have been met with, there was a certain amount of deformity of the lower end of the radius with congenital dislocation of the wrist; and in Mr. Smith's case there was an accessory semi-lunar bone in the carpus. Little, if anything, can be done by surgery for the relief of this deformity, though some benefit might 678 SPECIAL DEFORMITIES. possibly result from the division of any tendons that were preternaturally tense. A tendency to contraction of the fingers, which are drawn into the palm of the hand, is occasionally noticed; most commonly this commences in the little finger, and thence gradually extends to the ring or middle finger, which become so forcibly and firmly curved inwards, that their extension is not practicable. It commonly results from frequent and continued pressure on the palm of the hand, as in leaning on a round-ended stick in walking, or in those trades in which an instrument requires to be pressed into the hollow of the hand. On examining the contracted fingers, projecting ridges will be felt extending from the palm to their anterior aspects; and on endeavoring to straighten them, these ridges will be found to become stretched, and the palmar fascia to be rendered tense. The skin covering these ridges is usually healthy, but sometimes adhe- rent to them. So firmly are the fingers contracted, that by no effort can they be extended. The cause of this contraction of the fingers has given rise to a good deal of difference of opinion amongst surgeons. Dupuytren appears to have been the first who endeavored, by dissection, to ascertain its true character. He found, on examining a hand that was the seat of this disease, that after the removal of the skin, which was loose and flaccid, the contraction continued as before, and this, therefore, could not be its seat; but that the palmar fascia, which was exposed, was tense and diminished in size, whilst, from its lower aspect, some cord-like prolongations passed up by the side of the fingers, and that when these were divided, the contraction was immediately removed, the tendons, the bones, and the joints being perfectly sound. He considered these fibrous cords to be the digital prolongations of the palmar fascia, and consequently looked upon this membrane as the seat of the disease. M. Goyrand, who has carefully dissected hands affected in this way, states that these fibrous cords, which he also looks upon as the seat of the affection, are not prolongations of the palmar fascia, but are ligamentous structures that extend from its anterior inferior aspects to the sheaths of the flexor tendons, into which they are inserted oppo- site the second phalanx; being an hypertrophied condition of the subcutaneous filaments of fibro-cellular tissue that naturally exist in this situation. The treatment of this deformity consists in dividing each tense digital liga- mentous prolongation by a subcutaneous incision. This should be done oppo- site the second phalanx, where it is usually most tense; but, if the other finger- joints be affected, a separate section may be required opposite each phalanx. Should the skin be adherent to the fibrous band, it must be divided with it, and the finger then extended. FUNGUS OF THE DURA MATER. 679 DISEASES OF REGIONS. CHAPTER XLVIII. DISEASES OF THE HEAD AND NECK. FUNGUS OF THE DURA MATER. Sometimes without external or apparent cause, at others in consequence of a blow or fall, a fungous tumor grows from some part of the dura mater, usually on the vertex or the parietal regions. As it increases in size it produces absorp- tion of the cranium covering it; the bone becomes thinned and expanded, crackles like parchment on pressure, sometimes without being raised above its proper level, but more usually pushed up by the pressure of the growth be- neath, which at last protrudes under the scalp. More usually this perforation of the cranium is gradual, but in some cases it would appear to have been sud- den, the first intimation the patient had of the existence of disease being the presence of a tumor under the scalp. When the skull is perforated, the sharp edges of the circular opening can be distinctly felt; and the tumor that pro- trudes pulsates distinctly, as evidenced both by the finger and the eye. Symptoms of cerebral disturbance,—loss of sight, double vision, deafness, or epileptic fits, with fixed pain in the head, — usually precede, for a considerable time, the external appearance of the tumor. In some rare cases no such symp- toms indicated the existence of intra-cranial disease, and the first evidence of the disease has been the sudden protrusion of a pulsating tumor through the skull. If the tumor is compressed, and especially if attempts be made to push it back under the bone, giddiness, syncope, and convulsions are produced; and as the disease makes progress, death from paralysis and coma ensues. The result of the treatment of fungus of the dura mater is not very satisfac- tory; but yet as the disease would appear to be almost of necessity fatal, if left to itself, something should be attempted, not, however, until the tumor has fairly appeared through the bones. The scalp covering it should be turned back by a crucial incision, and the tumor exposed. The aperture in the skull through which it has protruded, may then, if necessary, be enlarged by the use of the trephine, or Hey's saw, so as to lay bare the full extent of the base of the tumor, which must then be carefully dissected away from the dura mater. Fungus of the cranium may occur which at first closely resembles the dis- ease just described. It differs from it, however, in this respect, that the tumor is devoid of pulsation and cannot be pushed back. It is vascular, in structure resembles the pulp of a red gooseberry, or a broken-down mulberry. In a case of this kind which I had an opportunity of seeing some years ago, the growth was successfully removed by my friend Mr. B. Phillips. Hernia Cerebri, resulting from wound or ulceration of the dura mater, has already been described (p. 290). Encephalocele or congenital hernia of the brain is a rare malformation, usually speedily fatal. Mr. Z. Lawrence finds that of 39 instances in which it occurred, 21 were males, 18 females; that the protrusion may vary from the size of a pea to that of a tumor exceeding the child's head • that the occiput is its chief seat, — of 79 cases, 53 being in this situation. In 6 instances, the subjects of this malformation reached an adult a«-e • in all the remaining cases they died early, or were still-born. Surgery offers little in these cases, though in one instance the protruding portion of brain was successfully sliced off, the patient surviving. 680 DISEASES OF THE HEAD AND NECK. Encysted Tumors of the Eyelids.—Small cysts are not unfrequently met with lying between the tarsal cartilage and the conjunctiva. At first they occasion no inconvenience, but as they increase in size they cause the conjunctiva cover- ing them to become injected, papillated, and granular, thus at last occasioning a considerable amount of irritation and lachrymation. These tumors may be removed either by being dissected out, or by being obliterated by inflammation set up in them. If the tumor is to be dissected out, the eyelid must be everted, and the cyst, having been exposed by dividing the conjunctiva covering it with a fine scalpel, must be drawn forwards with a hook and removed by a few touches of the knife. This little operation is, however, at times somewhat troublesome, and in preference to it I always induce the obliteration of the cyst by exciting inflammation in it. This may most conveniently be done by everting the lid, and then making a crucial puncture into the cyst with a lancet; the contents having escaped or been squeezed out, and the part well dried with a piece of lint, a pointed silver probe dipped in nitric acid should be quickly introduced through the puncture, the inside of the cyst stirred up and a little sweet oil having been poured over the lid, it may be replaced. Some induration will be left in the site of the cyst for a few weeks, but as that subsides the tumor will be found to have disappeared. Puncture of the Lachrymal Sac. — This operation is frequently required in those cases in which, the nasal duct having become obstructed, the lachrymal sac becomes distended by the accumulation of the tears, inflames, and either threatens suppuration, or, having given way, a fistulous opening has been left, below the under angle of the eye, through which tears often escape — the ordinary fistula lachrymalis. If a fistula have not already formed, the sac being merely distended, the passage through the nasal duct may sometimes be restored by the careful introduction of a very fine silver probe into it through the puncta, or the sac may be injected through the same orifice by means of one of Anel's syringes. Should these measures not prove successful, the permeability of the duct may be restored by catheterism from below; for this purpose a steel probe or sound, bent nearly to a right angle at about one inch from the extremity, should be passed into the nostril beneath the inferior turbinate bone; by a slight to and fro movement, the point of the instrument may be made to enter the orifice of the duct, and then by directing the handle downwards and inwards it will pass up along the canal into the lachrymal sac. Should these means, however, not prove successful in restoring a passage for the tears, or should a fistula have formed, the sac must be punctured and a style passed into it from above. This Fig. 255. operation may be performed in / the following way. The patient's ,/V head being well supported on / / the breast of an assistant, and ' / the lower eyelid having been put / well on the stretch by traction with the finger at the outer angle, the surgeon feels for the tendo oculi, the under surface of which is the guide into the lach- f rymal sac. In many cases, how- I ever, owing to the swelling and / induration of parts this tendon cannot be felt, and then the guide 1 must be the edge of the orbit ' below and a little to the outer side of the puncture. Having ascertained this, he rests the little finger on the cheek, and holding a strong DISEASES OF THE EAR. 681 narrow-bladed bistoury between the fore-finger and thumb, with the flat of the blade parallel to the face and the edge turned outwards he passes the point downwards and inwards well under the tendon of the orbicularis, the handle resting against the middle or outer third of the eyebrow (fig. 255). He then, by carrying the handle inwards and somewhat forwards until it rests against the bridge of the nose, causes the point to take a direction backwards, downwards, and slightly inwards, for about three-quarters of an inch, when the nasal duct will be fairly entered, which may be known by the bistoury supporting itself. The style may then be introduced along the blade, which should be firmly pressed inwards. Extirpation of the Eyebull.—This operation may be required for cancer of the eyeball, either of an encephaloid or melanotic character (fig. 256). It is also occasionally called for when in consequence of injury or disease one eye has become disorgan- Fig. 256. ized and the vision of the other is sympatheti- cally affected, and can only be preserved by the removal of the globe that is already useless. The operation may be performed in the following way: — The surgeon standing in front of the patient, makes an incision through the outer commissure of the lids as far as the edge of the orbit. The eyelids are then well everted and held apart with a wire speculum. The surgeon next passes a double hook into the globe and draws it well forward; then with a curved broad pair of scissors he divides the conjunctiva at its upper part, and then proceeds to cut across the several muscles of the orbit, and lastly the optic nerve. Should any of the structures within the orbit now present an unhealthy or suspicious ap- pearance he clears them out. The hemorrhage, which is usually rather abun- dant, may be readily arrested by a pledget of dry lint pressed into the orbit and retained by means of a circular bandage. If the lachrymal gland is diseased, it must of course be removed with the eyeball. If sound, it may be left, as it atrophies and gives no trouble. Extirpation of the lachrymal gland may be required for cancerous degenera- tion. This operation may be performed from the outer or from the inner side of the lid. Whenever practicable it should be done from the inner aspect. It may be performed in the following way: The outer commissure of the lids having been divided as far as the edge of the orbit, the upper eyelid is everted by an assistant; the surgeon then divides the conjunctiva covering the tumor, and fixing a hook in it draws it forwards, and with a few careful touches of the knife divides its attachments. After the removal of the tumor the lid drops into its normal position, and the commissure is closed by a suture. DISEASES OF THE EAR. Inflammation of the external ear, otitis, or ear-ache, is usually a rheumatic affection, and is characterized by intense pain, generally associated with hemi- crania — a kind of combination, indeed, of inflammation and neuralgia. This pain is much increased at night by warmth of the bed, and is generally accom- panied by throbbing and noises in the ear. The treatment, at first antiphlogistic, generally and locally, may advantageously, after a time, give place to quinine and the iodide of potass, with the external application of aconite. Occasionally the affection runs on to the formation of abscess in the meatus externus, attended by excessively painful throbbing. With the view of relieving this, leeching, poulticing, and early lancing will be required. 682 DISEASES OF THE HEAD AND NECK. Otorrhoea, a fetid discharge of a muco-purulent character, usually occurring in strumous children, and often associated with enlarged glands under the angle of the jaw, may be of two kinds; either proceeding simply from the mucous surfaces and being inflammatory, or it may be connected with necrosis of the petrous portion of the temporal bone, being associated with disease and destruc- tion of the tympanum, and necessarily of the internal ear. In the first case, astringent injections containing some of the chlorides in solution may advan- tageously be used, and will commonly arrest it. If, however, it proceed from disease of the bones, it is necessarily of a far more serious character, and the membranes at the base of the brain becoming irritated by the extension of the morbid action to them, convulsions and death usually eventually result. In some of these cases, phlebitis of the sinuses and of the cerebral veins ensues, and proves fatal to the patient. The external ear is occasionally the seat of special affections; thus, in idiots, hypertrophy of this structure is occasionally met with; and in gouty subjects, tophi, or gouty concretions, are occasionally deposited in it. Paget, Brack, and Panzetta have described a fibrous tumor that occasionally forms in the lobule of the ear, from the irritation produced by piercing it, and as "one of the penalties attached to the barbarism of ear-rings." These tumors are of a semi-malignant character, like the warty growths of cicatrices, and, after excision — which is their only treatment — are somewhat apt to return. We not uncommonly find that the meatus becomes blocked up by accumula- tions of wax, dark, indurated, and pipe-like; or forming balls and masses that lie in contact with the tympanum. These chiefly occur in individuals of the bilioso-phlegmatic temperament, and are a common source of temporary deafness amongst young people. They not only impair the sense of hearing materially, but are very apt to give rise to noises in the head, and crackling sensations on opening and shutting the mouth. Their presence is best ascertained by exami- nation with a well-constructed ear-speculum; those introduced by Mr. Toynbee, of a double convex shape, are the most useful. The treatment of these concre- tions consists in softening the wax by the introduction of a little glycerine into the ear for a few nights, and then repeatedly washing out the meatus by the injection of tepid soap and water, or water containing a little soap liniment, thrown in with a large syringe; as the fluid regurgitates from the tympanum, it will at length bring away the dark and hardened ceruminous masses. Polypi are occasionally met with, situated rather deeply on one side of the meatus: they are usually hard and fleshy looking, though sometimes soft and gelatinous, as in the nose; sometimes pediculated, but at others situated on a broad base, they produce serious inconvenience by obstructing the external ear, and require to be pulled off by means of forceps, or, if too firmly fixed for this, cut off with scissors; the surface from which they spring should then be touched with the nitrate of silver, so as to prevent a recurrence of the growth. Occasionally the cuticle of the external ear, and that covering the tympanum, becomes thickened and indurated, assuming a dull white appearance, which then may give rise to some amount of deafness. Under these circumstances, glycerine, the citrine ointment, or the solution of the nitrate of silver, will be extremely useful in restoring the healthy action of the integument of the part. It is not my intention to enter into the general pathology of the various kinds of deafness, or to discuss the causes of this affection. It may be stated generally, however, that it may arise from obstructions of the external ear from disease, ulceration and perforation of the tympanum, from various inflammatory affec- tions, chiefly of a subacute and chronic character, of the internal and middle ear; from paralysis of the acoustic nerve, dependent on cerebral lesions, or local paralysis; and, lastly, from obstruction in the Eustachian tube, or from disease of the throat. Mr. Toynbee has especially shown that many cases of so-called DISEASES OF THE NOSE. 683 Fig. 257. "nervous" deafness, together with singing, ringing, boiling, and other noises in the head, are in reality dependent upon chronic inflammatory affections of the internal and middle ear, and that the treatment best adapted for their cure consists in constitutional and local means of an alterative and antiphlogistic character. DISEASES OF THE NOSE. Epistaxis, or bleeding from the nose, is very common in children and in young people about the age of puberty, more particularly in girls antecedent to the menstrual period; it may either be of an active or passive character, but is most usually dependent on congestion of the mucous membrane. It may com- monly be stopped with- out much difficulty by the use of domestic re- medies, but occasionally it is so copious, amount- ing to many ounces, as to exhaust the patient and to require surgical interference. In the majority of cases the application of cold water and ice to the forehead and bridge of the nose, with rest, and a free aloetic purge, will ar- rest the bleeding. If, however, it do not stop in this way, it will be necessary to plug the nostrils. In many cases it may be sufficient to plug the anterior nares with a pledo-et of lint; very commonly, however, the posterior nares require to be plugged as well. This is best done by carrying a long piece of strong whip- cord aloncr the floor of the nose through the posterior nares into the pharynx, by means of Bellocq's sound; or, if this be not at hand, by threading the cord through an elastic catheter, and carrying this into the pharynx, then seizing the cord as it appears behind the soft palate, and drawing it forwards into the mouth, at the same time that the catheter is taken out of the nostril. In this way the string will pass through the nose, round the back of the soft palate, into and then out of the mouth (fig. 257). To the centre of the piece of string that hangs out between the lips, a plug of lint, about the size of the end of the thumb, should be firmly tied; this is then drawn up into the posterior nares by pulling on the end of the ligature that hangs from the nose, being guided m its passage behind the palate by the fingers introduced into the mouth. When the bleeding has ceased, it may readily be withdrawn by means of the string that hangs out of the mouth. . . , The mucous membrane of the nose is not unfrequently chronically inflamed, especially in strumous children; that portion of the membrane covering the tur- binate bones becoming thick, soft, and vascular, and projecting like a broad fringe from their surface. It is usually of a bright-red color and covered with muco-pus. This swelling at all times produces snuffling and a peculiar intona- tion of voice, but increases in wet weather, and then may become so great as seriously to obstruct the breathing. The treatment consists in attention to the general health; more especially to the eradication of the strumous diathesis. Much benefit may also be derived by the local application or injection of astrin- gents, as a strong solution of the nitrate of silver applied by means of a camel s- 684 DISEASES OF THE NOSE. hair brush, and sulphate of zinc and oak-bark lotions snuffed up, or injected by means of a proper syringe. In many instances, when this disease occurs in strumous children, change of air will effect the greatest amount of benefit. Abscess occasionally forms either on the mucous membrane or on the septum, and thus may lead to necrosis of the cartilages and bones, with much discharge and fetor, separation of these, flattening of the nose, depression of its bridge, and great deformity. These various forms of abscess, followed by necrosis, are commonly syphilitic, and then are associated with ulcers and a foul and fetid discharge, which has a tendency to cake upon their surface, forming dark and rugged crusts, and constituting the different kinds of ozoena. The septum may be the seat of chronic ulcerations consequent upon the irritation of decayed teeth, producing disease of the antrum, and escape of morbid secretion from this into the cavity of the nose, and this "coming in contact with the septum, produces thickening and ulceration of it. The treatment of these conditions must be conducted by the local application of nitrate of silver, black wash, and the chlorinated lotions; the general treatment consists usually in the adminis- tration of the dilute mineral acids, the iodide of potass, and sarsaparilla. Ulcers and fissures of a less serious character, though very painful and chronic, often occur at the angle of the ala and septum, or between the ala and tip; their treatment consists in touching them from time to time with the nitrate of silver, or in the application every night of the white precipitate or citrine ointment, at the same time that the general health is attended to, cachexy removed, and the strength restored, by the administration of iron, bark, and sarsaparilla. Lipoma is a chronic hypertrophy of the cutaneous and subcutaneous struc- tures, and of the cellular tissue of the nose, forming a large reddish-blue, vas- cular-looking, soft, tremulous, and lobulated mass, enveloping the end of the nose, and producing excessive deformity of it. There are all degrees of this disease, from mere clubbing of the end of the organ to the formation of a set of pendulous lobular tumors attached to it. The sebaceous glands and crypts appear to be the structures chiefly implicated in this disease. The patient's appearance may be greatly improved by the removal of these growths. This may be done readily enough by making an incision down the mesial line to the alar cartilages, and then dissecting it off these on either side; especial care, however, being taken in doing this not to encroach upon the nostril. This is best avoided by directing an assistant to keep his finger in it whilst the dissec- tion is being prosecuted, so that he may warn the surgeon of the too near approach of the knife. The surface is then left to granulate and cicatrize. The nose is frequently the seat of lupus and various forms of epithelial cancer, many of the deformities of this feature being referable to this affection ; indeed, lupus may be looked upon as almost specially affecting this organ, destroying one or both alae, the columna, or perhaps the whole of the nose. The considera- tion of the nature and treatment of these affections in this situation presents nothing special; but that of the cure of the deformities induced by them, which is full of interest to the surgeon, will be considered in detail when we come to speak of the plastic operations that are practised on the face. Tumors of very different structures and composition are met with in the nos- trils, and to all of these which possess the common characters of being pendu- lous and blocking up these passages, the term polypus is given. Thus surgeons commonly speak of the benign, the soft, the gelatinous or mucous polyp, as well as the sarcomatous or fleshy, and the malignant polyp. The term however should properly be confined to a soft and pendulous mucous growth, the fleshy and malignant polypi being merely varieties of fibrous or encephaloid tumors, springing from the bones in the nasal fossae, or from the ethmoidal and sphe- noidal cells. The true mucous nasal polyp, is a soft, moist, gelatinous tumor, of a greyish- yellow color when lodged in the nasal fossae, but when it descends into the ante- NASAL POLYPI. — MODE OF REMOVAL. 685 rior nares, or beyond them, and is exposed to the air, it becomes of a reddish- brown or purple tint, and somewhat shrivelled on the surface. It is usually lobulated, pedunculated, or bottle-shaped, and not very vascular except at the root, where it is permeated by largish thin-walled vessels that bleed freely on the slightest touch. In structure it is homogeneous, and composed of the elements of mucous membrane, covered by tesselated and ciliated epithelium, the ciliae of which may often be seen under the microscope in active movement after the removal of the growth, beating about the blood-corpuscles and fluid in which it lies. These tumors may grow from all points of the surface of the turbinate and ethmoid bones, and have indeed occasionally, though very rarely, been observed to project into the nose from the frontal sinuses and antrum. Most frequently they grow from the inferior spongy bone towards the outer side of the nostril, sometimes from the roof of the nares, but never take their origin from the septum. These polypi are usually numerous and of all sizes; as they increase, they commonly extend forwards into the anterior nares, but when of large size, they may be seen to reach into the posterior fauces, hanging down behind the palate. The symptoms occasioned by the presence of these polypi, depend on their interference with respiration and speech; and on the visual changes they occa- sion. The respiration through the affected nostril is impeded, the patient being unable to blow through it when directed to do so, and his speech is thick and nasal. There is snuffling and mucous discharge from the nostril, and all these symptoms are worse in damp than in dry weather. On examining the interior of the nose, by opening the nostril widely with the forceps or nasal speculum, and then directing the patient to blow down, the lower end of the polyp may be distinctly seen, and if large, will descend on a level with, or even beyond the nasal aperture. By the introduction of a probe, the size and extent of the tumor, together with the position of its pedicle, may be readily ascertained. As it grows, it impresses changes on the shape of neighboring bones, producing expansion and flattening of the nose, inducing caries of the spongy bones, and, interfering with the flow of tears down the nasal duct, occasions a watery state of the eyes, which, together with the change of shape in the features, and the peculiar character of voice and respiration, enables the surgeon at once to recog- nize the nature of his patient's disease. Polypi chiefly occur in young adults after the age of puberty; but they are not unfrequently met with at later periods of life. The diseases with which nasal polypi may be confounded are, 1st. Chronic thickening of the mucous membrane covering the spongy bones; from this the absence of any pedunculated growth around which a probe can be passed, toge- ther with the florid red character of the thickened membrane, and the fact of this almost invariably occurring in strumous children, are sufficient to distin- guish them. 2d. Abscess of the septum; from this the history of the case and the fact of the polyp never being attached to this part of the nose, will establish the diagnosis. 3d. There is a peculiar malformation of the septum consisting in a deviation of it to one side, that may at first be a little puzzling; but here the examination of both nostrils and the discovery of a depression on one side of the septum corresponding to the projection on the other, will reveal the true nature of the case. 4th. The fibrous and malignant tumors of the nostril will be found to differ sufficiently in consistence and appearance from the ordinary polypi to prevent their being confounded with them in many cases; but yet in some instances, much care will be required in coming to a definite opinion as to their true nature. Nasal polypi may generally be most readily removed by avulsion, with forceps; occasionally, but rarely, when they are very large with a broad base, and espe- cially when extending into the throat, they require the application of the liga- ture. In removing these growths by the forceps, instruments of good length 686 DISEASES OF THE NOSE AND CHEEKS. but very slender construction should be used, those generally sold are too thick ■ the interior of the blades should be properly serrated, and have a longitudinal groove, so that the root of the tumor may be tightly grasped. The patient should be made to sit on rather a low chair, and as there is generally a good deal of bleeding, a towel should be pinned over his clothes, and a basin placed before him to receive the blood and expectorated matters. The surgeon then having ascertained by the introduction of a probe, or by means of the blades of the forceps the situation of the pedicle of the polyp, grasps this firmly and pulls it off with a twisting movement of the hand. He proceeds in this manner, twisting off rather than pulling away polyp after polyp, until the whole of the nostril is cleared, which may be ascertained by examination and by directing the patient to compress the sound, and to blow through the affected side of the nose. The bleeding, which is often very free, stops on the application of cold water. At about the end of a fortnight the patient should be examined again, as it not unfrequently happens that small polypi, which had been prevented descending into the nares by the presence of the larger ones, now come down and require removal. These procedures must be had recourse to from time to time until all tendency to fresh formations of this kind has ceased. The ligature is chiefly required for those polypi that pass into the pharynx through the posterior nares. They may best he tied by passing a loop of strong whipcord, by means of a double canula, through the nose, and then, expanding the noose round the tumor in the throat and making it grasp its pedicle, knot it tightly. In some instances the polypi attain a great size, producing absorp- tion of the nasal bones, of the nasal process of the superior maxilla. In such cases it may be necessary, in order to extract them, to slit up the nose and pos- sibly clip away with forceps the osseous surface from which they spring. The fibrous polypi may grow to a large size, extending into the throat, and, perhaps, finding their way from the nose into situations where they are little expected. Thus they have been met with in the pterygo-maxillary fossa, and have been known to pass into the orbit through a hole in its inner wall. Malignant tumors of an encephaloid character occasionally form in the nos- trils, chiefly in children and young people, and, being attended by great expan- sion of the bones, with a fetid discharge of bloody matter and disintegrated por- tions of the growths, may end by speedily exhausting the patient. In such cases the surgeon may make an attempt to extract the growth by slitting up the nose, but it is seldom that anything very effectual can be done by operation, and it should be borne in mind, that some of the malignant growths that pro- ject into the nostrils take their origin from inside the cranium, or the sphe- noidal cells, and that the nasal portion is only the external protrusion as it were of a deeply-seated tumor. Calculi are occasionally met with in the nasal fossae, where they simulate a foreign body; and here extraction may be practised with a pair of forceps. But sometimes these rhinolites are situated under the mucous membrane. In two cases I have dissected round calcareous bodies of this kind, about the size of cherry-stones, from under the mucous membrane of the ala of the nostril in children. The frontal sinuses, though rarely, are occasionally the seat of disease. Abscess may form here with much pain and expansion, and possibly caries of their anterior wall, attended by the local signs of inflammation and with danger of concomitant inflammation of the membranes of the brain. Under such circumstances it may be proper for the surgeon to consider the advisa- bility of removing by a small trephine the anterior wall of the sinus, and thus giving exit/ to the retained pus. There are a few cases recorded in surgical writings, of polypi springing from these sinuses, and finding their way down into the nose after producing expansion of it and much inconvenience. Here CONGENITAL MALFORMATION OF LIPS. 687 Fig. 258. likewise the propriety of trephining and so extracting the morbid mass would have to be considered. The cheeks are occasionally the seat of encysted tumors and cancerous growths, either springing from their inner surface, or taking their origin as lupoid ulcers on the outside. The encysted tumors in this situa- tion may readily be removed by a little simple dissection. The cancroid ulcers and tumors, such as represented in fig. 258, seldom admit of operative interference. One of the most troublesome surgical affections situated in the cheek, is a salivary fistula, occurring in consequence of injuries, abscess, or operations, by which the parotid duct has been opened so as to cause a trick- ling of saliva through the external aperture that has been made into it. If the fistulous opening be recent, the lips of the external wound may be brought together and made to close, whilst the internal aperture is free. If it be of old date, a seton composed of a few threads may be passed into the fistula from the inside of the mouth, so as to allow the saliva to find its way along this, whilst union of the external orifice is attained by paring its edges and Wringing it together with hare-lip pins. My colleague, Mr. Marshall, has succeeded in closing an aperture of this kind by restoring the canal by means of a wire heated by galvanism, and then getting the external orifice to contract. DISEASES OF THE LIPS. The lips frequently require surgical interference. They may be the seat of tumors of various kinds, encysted or erectile, which require extirpation by the knife or ligature. In dealing with these, the surgeon must be guided by the circumstances of the individual case, but he should, if possible, avoid cut- ting through the whole thickness of the lip, and if compelled to do so, he must act°as will be described when we come to speak of cancer of this region. These growths more frequently occur on the lower lip. When encysted, they are usually small transparent tumors, with thin walls, containing a glairy straw- colored fluid. These should always be dissected out; mere excision of a por- tion of the wall being followed by recurrence of the disease. Erectile tumors of the lip are usually of an active character, and may either be excised, if of moderate extent and implicating the whole thickness of the lip; or if of large size and projecting from the mucous surface, they may be safely ligatured. I have had under my care some cases of nevus of the upper lip, implicating the whole substance of the part, and have successfully removed them by the repeated application of the potassa cum calce. . Hypertrophy to a great extent occasionally occurs in this situation. This is often of an cedematous character, being kept up by the irritation of fissures or cracks; if so, these must be cured, when the size of the lip will gradually diminish again. Sometimes, however, it becomes permanent, continuing alter the cure of the fissure; under these circumstances it may be necessary to excise a portion of the lip, and then to bring the edges together by means of sutures ^ Congenital malformation of the lips is of common occurrence. Contraction or even complete closure of the orifice of the mouth has been met with at 688 DISEASES OF THE LIPS. birth; such a condition must be remedied according to circumstances by the skill of the surgeon. By far the most common malformation in this situation, is the condition termed hare-lip. This consists of a perpendicular fissure through the upper lip. A similar condition has been described in the lower lip, but I have never seen such a case, or met with anybody who has. In hare-lip, the cleft is usually on one side only; and then it is said to be single, and most frequently, so far as I have observed, occurs upon the left side. Not unfrequently there is a fissure on both sides of the mesial line; and then the hare-lip is said to be double. The cleft never passes through the mesial line. When double, the fissure is deeper on one side than the other, and usually extends into the nos- tril, though sometimes it stops short of that. In these cases, the nose is usually flattened and expanded, and between the fissures there is always a cen- tral or median lobule, consisting of the inter-maxillary bones in a rudimentary condition; to this a small triangular piece of lip is commonly attached. In many cases this is pushed forwards, and tilted on its base, so that the alveolar border projects forwards. Sometimes the projection is so considerable that it is attached to the tip of the nose. The cleft in hare-lip corresponds to the line of junction between the embry- onic inter-maxillary bones and the superior maxilla. The fissure when single, may be confined to the lip, but in the majority of cases it extends to the upper jaw. In other cases again, the fissure extends back into the palate; this more frequently happens when the hare-lip is double, and in these cases every variety of palatal deformity is met with. The cure of hare-lip can only be effected by a properly conducted operation. In the performance of this, the first point that has to be determined is the age at which it should be done. On this there has been, and is still, a good deal of difference of opinion. Surgeons generally are, however, I think, agreed that the operation should not be performed during dentition; at all events not during the cutting of the incisor teeth, when there is much local excitement and general irritability of the nervous system; but they are not agreed as to whether it should be done before or after dentition. In support of the opinion that it is more prudent to wait until after this period, it is alleged that very young infants are especially liable to convulsions; that the performance of operations in them is troublesome; and that it interferes with suckling. These statements, however, are not carried out by what we meet with in practice. I think that there is no evidence to show that there is any danger in operating during early infancy; indeed, I believe that very young children, those but a few weeks or months old, bear operations remarkably well. I have repeatedly operated at these tender ages, not only for hare-lip, but for hernia, the removal of tumors, nevi, the division of tendons, &c, and have never seen any bad result follow. Besides this, the performance of the operation is easier at a very early age than when the child has reached its first or second year; when its intelligence being more developed, it knows what it has to suffer, and screams and struggles more than a very young infant does, whenever it sees the surgeon, or he makes an attempt to examine the wound or dressings. After the opera- tion, also, the child will, when young, take to the breast without difficulty and with the greatest avidity. The act of suction is advantageous, as in it the sides of the incision are more closely compressed and brought together. At very early ages union of the wound takes place with great readiness and solidity, and as no time has been given for the rest of the features to become distorted, there will not be that permanent flattening and deformity of the face which is apt to continue after the hare-lip is cured if the operation be deferred to a more advanced age. For these various reasons I agree with Dubois and Fergusson, that the operation had best be performed early, and, if possible, at OPERATION FOR HARE-LIP. 689 about the sixth week after birth, or from that to the third month, which may, I think, be considered the time of election for this procedure. In the treatment of hare-lip, there are three points that require special attention: 1st. To procure union by the direct adhesion of the cut edges of the fissure; 2d. That the union should be attended by as little deformity as possible; and 3d. The avoidance of all traction on the line of incision that may interfere with these results. These principles of treatment are carried out by paring the edges of the fissure freely, bringing them together by means of the twisted or interrupted suture, and taking off all tension by means of strips of plaster and the cheek-compressor. But the details of the treatment vary so much, according as the fissure is single or double or complicated by more or less projection of the inner-maxillary por- tions, that the steps of each operation require to be separately described. , The operation for single hare-lip is performed in the following way: — The child having been well pinned in a jack-towel that swathes it tightly, the surgeon, sitting down, places his feet on a stool so as to raise them, and cover- ing his knees with a piece of tarpaulin, holds the child's head firmly between them. He then, putting the lip on the stretch by seizing the extreme edge of the cleft with a pair of artery forceps, pares the edges of the cleft by transfixion with a narrow-bladed bistoury, or fine scalpel, from above, downwards, first on one side, then on the other, taking care that the incisions unite neatly and cleanly above the upper angle of the fissure, which must be well cut out; and that they extend sufficiently far outwards to cut away the rounded portion of the prolabium which forms the side of the base of the fissure. Care should be taken that enough is cut away; there is more danger usually of taking too little than too much. In single hare-lip, where the lips are very lax, the incisions may be straight, but in double hare-lip they should be somewhat concave inwards; in this way there is less likelihood of an unseemly notch being left (fig. 260). Fine hare-lip pins, made of soft iron wire, with steel points, should then be deeply introduced through the lip from one side of the fissure to the other. At a very early age one pin may be sufficient; at a later period two are required. If two are used, the lower pin should be introduced first underneath, or through the cut labial artery, in such a way that its pressure may stop the bleeding from this vessel, which is often rather free. In passing this pin, great care should be taken to bring the opposite sides of the fissure well in contact, so as to be on a level below, that no irregularity may be left in the prolabium; the twisted suture is then applied in the usual way, first round the lower pin, and then round the upper one, and lastly the two are united by a few cross turns (fig. 259). The pins are Fig. 259. then cut short, and a piece of plaster put under their ends to prevent excoriation of the skin. In addition to the pins and twisted suture, I invariably introduce one point of interrupted suture through the mucous membrane of the lower part of the fissure, just inside the mouth; and I look upon this as of great conse- quence in order to prevent the notching, which is otherwise very apt to occur, in consequence of that portion of the incision between the lower pin and the edge of the lip being kept open by the child in suck- ling, or protruding its tongue against it. At the end of about the third or fourth day, the pin may be removed by oushing it through the lip by a gentle rotatory movement, in such a way that the cut end does not tear or lacerate the aperture in the lip. The sutures may be left on for two or three days longer; the lip being supported by a strip 44 690 DISEASES OF THE LIPS. of adhesive plaster, or by a piece of lint soaked in collodion, which I have found to form a firmer and more secure support than the plaster, and should indeed be continued for about a fortnight after the operation, so as to prevent stretch- ing of the cicatrix and notching of its lower Fig. 260. part. The point of interrupted suture may be left in for about six days. If the fissure be wide, and child restless, so that there is danger of the parts being dragged upon dur- ing its screaming or crying, it is a very good plan to apply the spring cheek-compressor, invented by Mr. Hainsby, here represented slack (fig. 260). The operation for double hare-lip is per- formed on the same principles as that for the single form of the disease, viz., of pro- curing union by adhesion between the oppo- site surfaces. The difference in the opera- tions consists in dealing with the intermedi- ate portion of the lip and alveolus. If this portion of the lip be small or fixed to the tip of the nose, as in fig. 262, it should be cut off, as it would prevent the lateral segments coming into proper apposition; but if large, it should be well pared on either side, and transfixed by the hare-lip pins, and thus be interposed between and united to the pared lateral surfaces; indeed, it is always advisable not to remove this, unless it be awkwardly situated, as in fig. 261, when left, though the union may not appear quite so perfect and uni- form as it would if the lateral halves had been directly united, yet eventually the case will turn out better; the central portion becoming developed, and forming the natural mesial projection of the lip, which is lost when the lateral halves are directly united. In some of these cases great nicety is required in planning the incisions, and in the introduction of the sutures. The central portion is most advantageously pared in a somewhat concave manner, so that the freshly cut edges of the lateral halves are received into and more accurately Fig. 261. Fig. 262. fitted upon it. When the intermediate alveolus is small and rudimentary, and more particularly, if it be very prominent, it had better be cut off with a pair of bone-nippers, and the lip brought together over the cut surface. Most com- monly there will be free bleeding from the dental artery deep in the bone, and which requires to be touched with a red-hot needle or wire before the hemor- rhage from it will cease. Whenever practicable, however, this central portion should be saved, as by its removal not only are the incisor teeth sacrificed, but OPERATION FOR HARE-LIP WITHOUT PINS. 691 a gap is left which causes some deformity in after-life. If the intermediate por- tion be large and not projecting, it should be left, and the edges of the lip brought together over it. If it be projecting and large, it should be bent forcibly back; this is best done by seizing it with a pair of necrosis forceps covered with wash-leather. If, by any chance, union by the first intention fail, the lip tearing open, the granulating surfaces must be brought in contact with one another again, when they will in all probability cohere as readily as they would have done in the first instance. Treatment by Simple Suture.—During the last few years I have been in the habit of treating hare-lip of all kinds, double as well as single, with the simple interrupted suture alone, without using any pins. I have in this way treated most successfully many cases in children, whose ages have varied from a few days to four years, with most satisfactory results, and with less marking of the lip than I have ever seen attend union by means of the twisted suture, to which I now generally prefer it as being equally safe, more simple, and followed by less scarring of the lip. When the fissure is single, the edges, having been pared in the usual way, should be brought together by two points of suture, the first passed deeply near the free edge, and in such a way as to compress the cut coronary artery; the other nearer the nasal angle. These sutures should be of thick well-waxed den- tist's twist, that will not cut out too readily. A point of fine interrupted suture should then be inserted through the mucous membrane inside the lip. The lip may then be supported by two narrow strips of plaster, one placed between the sutures, the other between the upper suture and the nose. On the third day the upper suture should be taken out, but the lower one may be left in for a day or two longer, when it and the one through the mucous membrane may be removed together, unless the latter has already cut its way out. The lip must then be supported for a few days with a strip of plaster. In the ease of double hare-lip the same plan is to be adopted, first on one side, then on the other; but in these cases, as the gaps are wider, and the tension, more particularly when the intermaxillary prominence is very pro- jecting, is apt to be considerable, it is necessary to support the cheeks, and thus to prevent undue traction on the stitches, by means of the cheek-com- pressor. In this way all risk of the stitches cutting out before union is com- pleted is avoided, and excellent and solid union will speedily be obtained even in the worst cases of double hare-lip, with great intermaxillary projection and fissured palate. Ulceration is not unfrequently met with on the prolabium, frequently of a simple character, though chronic, when it will commonly yield to the application of nitrate of silver and to proper constitutional treatment, more especially the administration of the preparations of arsenic. Not unfrequently warty growths and various forms of epithelial cancer and cancroid diseases appear upon the lips. These affections are not removable by therapeutic means, and require surgical interference. Cancroid ulcers of the lip either commence as warty growths, which gradu- ally ulcerate like the ordinary forms of tubercular lupus, or beginning as a crack or fissure become indurated, the edges having a tendency to spread, the submaxillary glands to become involved, and the disease eventually to prove fatal by the pain, exhaustion, and constitutional irritation induced by them. These ulcers almost invariably occur in men, affect the lower lip, and are met with after the middle period of life. Of 14 cases in which I have operated, 7 were above sixty, and 4 between fifty and sixty years of age; in one case only did the disease occur under thirty. This disease is at first entirely local, often being induced by some irritation, as by a rugged, broken tooth, or by smoking a clay pipe, and when removed does not, I believe, very commonly return. At least, of the very many cases that have been operated upon at the University 692 PLASTIC SURGERY OF THE FACE. College Hospital, I have only known one patient return with a recurrence of the disease, and I do not recollect any case of secondary affection of this de- scription apply to that institution from other hospitals; I cannot, therefore, but come to the conclusion that the operation for cancer of the lip frequently rida the patient permanently of disease. When the glands under the jaw are enlarged in these cases, it may be a question whether the operation should be done; but I think decidedly that extirpation of the disease and removal of the enlarged glands, provided the surrounding soft parts are not involved, should be practised, if the patient be otherwise in a good state of health, as he will thus be placed in a more favor- able condition than he was before the operation, and will have a better chance of prolongation of life. When once the true nature of the disease has been ascertained, the opera- tion should be performed with as little delay as possible; but before it is done, it is well that any very prominent or broken tooth should be removed, and the tartar cleared away from the incisors. The operation requires to be somewhat modified according to the situation and extent of the affection; if this be tole- rably limited, a V shaped cut, extending widely around it, and carried suffi- ciently low to include any indurated prolongation of the absorbents, should be practised; the edges of the cut should then be brought together by two hare- lip pins with a twisted suture, just as in the case of a simple hare-lip. When the disease occupies a considerable longitudinal extent, but does not dip down very deeply, a slice of the lip should be shaved off, including the whole of the morbid structure; and it is often surprising, under these circumstances, how little deformity will result, so soon as the disease is removed, the tissues of the lip speedily rising to their natural level, and thus preventing any material de- formity being left. In some cases the disease occupies a square surface, and then it is necessary to excise a large portion of the lip; when this is done, a considerable gap will be left, which requires to be filled by some plastic opera- tion, such as we shall immediately consider, which may most conveniently be done at the time that the excision is practised. PLASTIC SURGERY OF THE FACE. By plastic or reparative surgery is meant those processes by which mutila- tions are repaired, and loss of structure replaced. As these operations are principally practised for deformities of the face, we may conveniently discuss them here. It has been long known to surgeons that parts of the body may retain their vitality sufficiently to become again adherent when attached but by a very narrow tongue of tissue, to the part from which they have been all but separated. This has often been observed in cases of injuries of the face and fingers, portions of which have been nearly completely severed, and yet have united again on being replaced. But there are even a sufficient number of cases on record to show that certain parts, when completely separated, may, after being replaced, again become adherent. The most remarkable instances of this kind are those related by Dr. Hoffacher, and which are attested by Chelius and Velpeau. Dr. Hoffacher was officially appointed to attend as surgeon at the duels which were at one time frequent amongst the students at Heidelberg, and, as at these encounters broad-swords were used, he had an opportunity of seeing a considerable number of incised wounds, and has related no less than 16 cases in which portions of the nose, lips, or chin, had been sliced off, and being put on again, contracted adhesions. Amongst the most remarkable of these, is a case in which the end of the nose was sliced off by a cut with the broad-sword, and fell under a chest of drawers; it was not found for some time, but on being recovered and washed, was stitched on, when it became firmly attached. In another instance, a dog that was in the room PLASTIC SURGERY OF THE FACE. 693 snapped up the detached portion of the organ as it fell to the ground, but the nose being immediately taken out of the animal's mouth and put on again, became firmly fixed! In order that union should take place between parts that have been separated completely or nearly so, and the rest of the body, it is necessary that they be soft and vascular, and more especially that their structure be of a homogeneous character, such as is met with in the tissues of the face; where no very large blood-vessels, nerves, tendons, or bone are found. It is the same in plastic operations, which succeed best under similar conditions of tissue, and which are conducted on the same principle as an attempt at union in a partially severed structure. Union in plastic operations is effected by primary adhesion between the flap of skin that is partially detached, and the raw surface on which it is laid and attached. Should, however, this mode of union fail from any accidental cir- cumstance, the surgeon need not despair, as the parts may unite by adhesive inflammation or even through the medium of granulation in a very satisfactory and complete manner. For proper union to be effected it is necessary that the edges be cleanly and evenly cut, so as to adjust themselves accurately to one another. This may often be most skilfully effected by making the incision in the part that is to receive the flap somewhat oblique or bevelled, thus securing a more accurate adaptation of the edges. After the flap has been formed and the part in which it is to be transplanted properly pared, the operation should be delayed a few minutes until all bleeding has ceased. This is of much importance, as the interposition of a layer of co- agulated blood will materially interfere with union. In bringing the parts into apposition great care must be taken that no undue traction or constriction be exercised, lest their circulation be interfered with, and their vitality be endangered. The parts may be maintained in apposition by sutures, collodion, or the appli- cation of a strip of isinglass plaster. The sutures should be as fine as possible, introduced with a small needle, and knotted on the sound parts. Occasionally fine hare-lip pins may advantageously be used. In some instances instead of sutures a small spring forceps (fig. 52), termed a " serrefine," may be employed, but most generally interrupted sutures are the best. The use of collodion is of great advantage in plastic surgery, as it not only secures adhesion, but by ex- cluding the air lessens the chance of suppuration. For a plastic procedure to succeed, it is absolutely necessary that no morbid action be going on in the seat of operation, and not only that none be actually in progress but that all have ceased for some considerable time. This is more particularly the case when the deformity for the remedying of which it is prac- tised has resulted from syphilitic or cancerous ulceration. In both cases it is necessary to see that the constitution is sound as well as that all local disease has been eradicated; otherwise the irritation of the operation might set it up a°ain and the new flap be invaded and destroyed. From want of this precaution I have more than once seen disappointment result. As a general rule, plastic operations practised for the repair of mutilations from injury are more successful than those that are had recourse to after disease. The patient's general health must be in a sound state lest the adhesive action, on which the success of the operation is dependent, be interfered with. No routine system of treatment should be adopted, but a few days of rest, good diet and a dose or two of aperient medicine, may be prescribed before the operation is proceeded with. In the after-treatment of the case a nourishing but unstimulating regimen should be observed. In performing these various plastic operations three methods have been em- ployed. In the first, the flap of skin that is intended to repair the lost 694 PLASTIC SURGERY OF THE FACE. structure is transplanted from a distant part, as the arm for instance. This operation, which was introduced by the Italian surgeon, Tagliacotius, and hence commonly called by his name, has in a great measure fallen into disuse, on account of the difficulty of its execution, and the great uncertainty of obtaining a successful result. The second plan consists in transplanting the reparative structure from some part in the neighborhood of the organ to be repaired; the skin from the forehead, for instance, being used for the formation of a new nose ; that from the chin for the restoration of the lost lip. This procedure, which seems first to have been adopted by the natives of India in restoring the loss of the nose, is the method that is most commonly employed in this country in plastic operations on the face. The third method consists in loosening the skin by a process of subcutaneous section to some distance around the part to be repaired, and then drawing it forwards with or without incision through its substance. This gliding operation is chiefly practised for the closure of fistulous openings. It is principally for deformities and loss of the nose and lip that plastic opera- tions are of much service; they may, however, occasionally be had recourse to in other situations, as about the cheeks and eyelids, but seldom with an equal amount of success. In the practice of this very interesting branch of surgery there is much opportunity for the display of manual dexterity, on which, indeed, almost the whole success of the operation depends, and a vast deal may be done in apparently the most unpromising cases by management, skill, and patience. In these operative procedures the names of Serres, Dieffenbach, Liston, and Jobert, deservedly take the first rank. The only plastic procedures the performance of which can be reduced to dis- tinct rules, are those for the restoration of a lost nose, rhinoplastic, and for partial loss of a lip, cheiloplastic. As these operations are commonly practised for loss of the part from cancroid, strumous, or syphilitic disease, especial care must be taken before they are commenced, that all morbid action has entirely ceased for at least a year or two, lest the irritation of the operation set it up again, and thus the new flap be invaded and destroyed; I have more than once seen much disappointment ensue from want of attention in this respect. When the operation is performed for cancroid disease, ablation of the morbid part may be done at the moment of operating — the affection being a local one; when for struma or syphilis, the disease is constitutional, and care must be taken that all morbid action has thoroughly and completely ceased. RHINOPLASTIC OPERATIONS. Restoration of Columna. — When the columna and a portion of the septum are destroyed, a large gap is left at the nasal aperture, and the nose becoming flattened in consequence of its tip falling in, great deformity necessarily results. The upper lip also losing that amount of support which it receives from the columna, becomes pendulous, projecting, and thickened at the end, thus adding to the disfigurement. The restoration of the columna is effected from this thickened and prominent upper lip, which, by being reduced in size, is rendered far more shapely. The operation consists in cutting through the whole length of the lip from above downwards on either side of the mesial line so as to leave a tongue about one-third of an inch in width. This is then turned up, and its end being well pared, and the under surface of the tip of the nose properly vivified, it is fixed there by means of a fine hare-lip pin and twisted suture, which should be left in for about four days. Union takes place in a few days, but until this is firm the new columna must be properly supported with narrow strips of plaster fixed to the cheeks on either side. No twisting of this small flap is required, as the mucous surface speedily becomes cutaneous, and vice versa. The division in the upper lip must be treated in the same way as an FORMATION OF A NEW NOSE. 695 ordinary hare-lip, and unites without difficulty, lessening greatly the deformity in this part. Restoration of Ala.—When one ala only is deficient, the rest of the nose being sound, a flap of skin of the proper shape to restore the deformity may be raised from the cheek and applied to the edges of the part requiring it, pre- viously pared, and fixed there by a few points of fine suture. If the loss of the substance of the ala be very considerable, or if it extend to a part of the body of the nose, then it is more efficiently restored by bringing a long narrow flap from the forehead in the way that will immediately be described. In the majority of cases the destruction of the ala and of the body of the nose is so considerable, that other plans than those just described are required for the repair of the deformity. The methods that may be had recourse to are the Tagliacotian and the Indian operations. Occasionally fistulous openings are met with through the nasal bones leading into the interior of the nostrils. Such apertures as these are, perhaps, best closed by paring the edges and then bring- ing forward a flap of neighboring skin by the gliding operation. Restoration of Nose. — The Tagliacotian operation consists in taking the integument and cellular tissue required for the repair of the lost organ from the inside of the arm. Here a flap of sufficient extent should be marked out and dissected up with its subjacent cellular tissue, leaving it merely attached to the limb by a root at its distal end. No attempt at fixing this flap to the nose should be made for at least a fortnight, during which time it should be kept upon a piece of wet lint, and allowed to thicken, granulate, and become vas- cular, so as to fit itself for adhesion to the new surface to which it is to be applied. The remains of the deformed nose having then been properly pared and the flap shaped, they must, after all bleeding has ceased, be properly adjusted and fixed to one another by points of suture. The arm must then be closely attached to the head so as to be as nearly as possible immovable. At the end of about ten days when adhesions have taken place, the connecting medium may be cut across and the part left to be supported by the vitality that it may gain from the new surface to which it is now attached. This process is com- paratively seldom had recourse to, for obvious reasons. The uncertainty of maintaining the vitality in the flap, the extreme tediousness of the prolonged constrained position in which it is necessary to keep the patient, and the great difficulty of guarding against movements of the arm, especially during sleep, and which, however slight and involuntary, would be sufficient to disturb union between the opposed surfaces and occasion the failure of the operation, have caused this plan of procedure to fall into disuse; and it is now, I believe, universally abandoned by surgeons in this country, having been replaced by the more certain procedure of borrowing the skin for the new nose from the forehead. This, the Indian operation, a knowledge of which was brought to this country by Mr. Carpue, in 1814, is extremely successful in its results, though requiring a good deal of nicety for its proper execution. The operative procedures required by this method are somewhat complex, and may conveniently be divided into three distinct periods; the 1st consisting in the dissection of the flap from the forehead, and its attachment to its new situation; the 2d, the separation of the root of the flap where it is turned down from the forehead, and the formation of a proper bridge to the nose; and the 3d, the formation of the columna nasi. 1st. In the shaping of the flap, care must be taken that it is of sufficient size, as durin"- the after part of the treatment, it often has a tendency to shrivel, and more inconvenience usually results from its not having originally been made large enough than the reverse. The size adapted to the particular face may best be judged of by moulding a thin piece of gutta percha to the nose, then flattening it out by dipping it in hot water, and using this as the guide 696 PLASTIC SURGERY OF THE FACE. for marking the outline of the flap upon the forehead. This should be traced with tincture of iodine, which will not wash off so readily as ink by the flow of blood, which is often rather free. This flap should be of the shape in fig. 263, taking care that it is rather square at Fig. 263. the angles, and not too much rounded off. The size will necessarily vary ac- cording to the character of the counte- nance, and the extent of loss that has tu be repaired. When the whole of the nose requires restoration, it is usually necessary to make it about two and a half to three inches in length, by about the same in width at the broadest part. It may either be taken from the middle of the forehead, or obliquely from one side. If the latter, the right side is the most convenient. It must now be dis- sected off the forehead; in doing this care must be taken not to remove the pericranium, but at the same time to cut the flap as thick as possible, especially at its root between the eyebrows. It must also be but little handled, and, above all, not pinched, either with fingers or forceps. The dissection should be com- menced at the root, so that the outline may not be obscured by blood; and this part should be left long, in order to admit afterwards of a very gradual and easy twist. In order to facilitate this, it is also desirable to make the incision on the right side a little lower than that on the left. After the flap has been raised throughout the whole of its extent, a piece of wet lint should be applied to the forehead, with a view of arresting the bleeding, before the next step is taken. This consists in paring the surface and edges of the stump of the nose, and removing the integuments from it in such a way as to leave a triangular raw surface. In doing this care must be taken, whilst a good base of attachment is left, not to remove the parts too widely, lest the cheeks, by separating, have a tendency to gape too much, and the nose to become flattened out. The integu- ments also should be dissected away in such a manner as to form a deep groove shelving inwards, so as to receive and hold the flap more securely and with less overlapping of the edges. The operation must now be discontinued for a few minutes until all bleeding has ceased, and the cut surfaces have become glazed; this point is of great importance in securing direct adhesion, and must be care- fully attended to. The bleeding having been arrested by exposure to the air, and by the torsion rather than the ligature of any spouting branch, the flap from the forehead should be brought down by a twist from left to right, and attached by a few points of fine suture on either side to the edge of the incision around the nasal aperture. A pledget of soft lint, moderately greased, should now be gently insinuated under the flap, the lower part of the incision in the forehead drawn together by a point of suture, but not so as to constrict the root in any way, and the rest of the exposed surface covered with water-dressing. The parts will then present the appearance of fig. 265, taken from a patient of mine the day after the operation. Fig. 264 represents the deformity for which the operation was performed. The patient should be put to bed with a piece of soft lint laid over the whole of the face, so as to maintain its temperature, and if it be winter, placed in a room that is kept well warmed day and night. The diet for the first few days should be simple, but abundant, consisting chiefly of nutritious slops. The dressings must not be disturbed for three days; by this time, if all goes well, the flap will be found somewhat tumid, warm, and sensitive, but pale in FORMATION OF A NEW NOSE. 697 color. The plug in the nose will now require changing, lest it be rendered offensive by the discharges; its withdrawal and the substitution of another Fig. 264. Fig. 265. must be done with the greatest gentleness, the surgeon bearing in mind that any undue pressure or traction may destroy adhesions and prove fatal to the vitality of the flap. If the sutures produce no irritation, they may be left in till the fifth or sixth day, by which time the adhesions will be tolerably perfect, and they may with safety be cut and withdrawn. As the adhesions strengthen and the vitality of the flap improves, it must be elevated by putting underneath it a larger plug of lint, for which, after a time may be substituted a small gutta- percha tube moulded to the figure of the inside of the nose. QMema of a some- what solid character is apt to come on in the flap, giving it a white appearance, but this is of little moment, and will gradually subside as the circulation through it becomes more actively established. The flap gradually becomes thicker and firmer, throwing out granulations from its under surface, which eventually becomes clothed with mucous membrane. The wound in the fore- head must be dressed like an ordinary ulcer, and be well touched with nitrate of silver from time to time, to insure its contraction. It usually cicatrizes with great readiness, and leaves remarkably little deformity. 2d. The next step in the operation is the division of the root of the flap, which may be done about a month after it has been fashioned, when its vascu- larity, through its lateral adhesions, will be perfected; the division of the root is best done by passing a narrow-bladed bistoury under the twist, and cutting upwards towards the eyebrows, removing a wedge-shaped portion of the soft parts so as to make a smooth and proper bridge. 3d. The addition of the columna is now all that is wanted to make the nose complete. This must be made from the upper lip at the same time perhaps that the bridge is fashioned, and may be cut and fixed in the way that has been already described in speaking of the restoration of this feature, the interior of the apex of the new nose having been well pared to receive it. The columna requires to be well supported by means of a narrow strip of plaster passing from one cheek to the other, and usually requires a good deal of fashioning before it is perfect; indeed this is the part of the operation that I have found always most troublesome, and requiring most attention. The new nose must be con- tinued to be supported from beneath, for some months after its formation, by plugs of lint, or small gutta-percha tubes, as it will evince a great tendency to contract and to alter in its general outline and shape, becoming, if the surgeon 698 PLASTIC SURGERY OF THE FACE. is not careful, either depressed or dumpy. The sensibility of the new nose is entirely destroyed for a time after the division of the bridge, but it slowly returns from all sides, appearing first in the neighborhood of the adhesions between it and the cheeks, then near the columna, next in the bridge, and thus Fig. 266. Fig. 267. the organ at last has its sensations restored; for this, however, several months will usually be required, and the part in which it returns last of all is its central portion. The annexed cuts give a very faithful representation of a patient on whom I operated, before and after the restoration of the lost organ (figs. 266 and 267). The success of the case will depend very greatly upon the minute attention that the surgeon bestows on the details of the operation, and on the care that he takes in the after-treatment. During the operation the chief points to be attended to are, that the flap is made of sufficient size, and that all oozing has ceased before the cut edges are brought into contact, and that no tension or constriction be exercised. The principal causes of failure in the operation or in the result, so far as concerns the after-appearance of the patient, are in con- sequence of gangrene of the flap, in whole or in part, taking place from the root being too narrow, too tightly twisted, or the flap too roughly handled in its dissection. So also if it be cut too small and not properly supported after- wards, the result will not be very satisfactory. Other accidents occasionally happen; thus erysipelas may occur, destroying at once the vitality of the flap, or, coming on at a later period, when the new nose will slough under the attack of inflammation, which it has not sufficient vitality to resist, as happened in one of Mr. Liston's earlier cases; or it may be destroyed by a return of the lupus which proved destructive to the old one. Hemorrhage may also occur from underneath the flap. In the last case operated on by Mr. Liston before his death, and which was completed by Mr. Morton at University College Hos- pital, hemorrhage to the extent of more than a pint took place on the ninth day without any evident cause, from under the flap, and could only be arrested by plugging. Lastly, the operation is not without its dangers. Dieffenbach lost two patients out of six on whom he operated in Paris; their constitutions, pro- bably, being in an unfavorable state. When the nose is depressed and flattened, in consequence of the loss of the cartilages, vomer, and septum, though the external parts remain entire, Dieffenbach has proposed a plan for raising it, by slitting it longitudinally FORMATION OF A NEW LIP. 699 into three pieces; dissecting the lateral slips from the osseous attachments, then paring the edges to such an extent that they overlap, and stitching them together, to bring the whole organ forwards by pushing long hare-lip pins across its base, so as to elevate and narrow its attachments, which are brought more into the mesial line. Fergusson has improved this procedure by not slit- ting the nose down, but by dissecting it away from the bones from within the nostril, and then pushing long steel-pointed silver needles across from cheek to cheek, and twisting their ends over perforated pieces of sole leather, through which they had previously been passed, thus bringing the whole organ bodily forwards. The columna is next fashioned in the way that has already been described, and the nose thus completed. CHEILOPLASTIC OPERATIONS. The restoration of a portion of the lip, that has been lost by accident or disease, is not so readily effected as that of the nose, but yet, a good deal may be done to restore the deformity. The plan originally introduced by Chopart consists, when it is the lower lip that is deformed, in carrying an incision from behind the lower jaw, down to the os hyoides, so that a square flap may result, which is detached from above downwards. This flap is then brought up and fixed to the pared edges of the remaining portion of the lip by points of suture, the head being kept .properly inclined, in order to prevent undue tension. After sufficient union has taken place to preserve the vitality of the flap, its lower attachment may be divided. The flap should, if possible, not be twisted, though it is not always practicable to avoid this. This operation is not usually very satisfactory in its results, as the new flap is apt to become cedematous and inverted at the edge, or the flow of saliva may interfere with proper union. In those cases in which the greater portion of the lower lip has been ex- Fig. 268. cised for cancerous disease affecting its upper margin, the most successful procedure for the restoration of the deformity, consists in a modification of the plan recommended by Serres, and from this I have derived excel- lent results, as in the case which is here re- presented (fig. 268). The object of the operation is to raise the lower lip on a level with the incisor teeth. This is effected in the following manner: an incision, about three quarters of an inch in length, is made directly outwards from the angle of the mouth, on either side, into the cheek; from the extremity of this, a cut is carried ob- liquely downwards on to the upper margin of the lower lip, so as to excise the included triangular piece; the lower lip is then dis- sected away from the jaw, from the inside of the mouth, and a V shaped piece taken out of its centre. By means of a hare-lip pin on either side, and a point of suture, the incisions in the angle of the mouth are brought accurately together, and in the same way the vertical one, in the centre, united (fio-. 269). In this way the whole of the lower lip is raised, and brought more forwards. If care has been taken, in removing the cancer from the edge of the lip, to leave the mucous membrane rather long, which may always be done, as the skin is affected to a greater extent than it, a good prolabium may be formed, and the restoration effected with but little deformity. Care must be 700 PLASTIC SURGERY OF THE FACE. taken to prevent union occurring between the inside of the lower lip and jaw by the interposition of a strip of oiled lint. Mr. Syme has introduced an operation by which the cancerous ulcer of the lower lip having been removed in a triangular form, by two incisions extending from the angles of the mouth to the chin, the cuts are carried obliquely down- wards and outwards, on each side, under the body of the jaw, and made to terminate in a slight curve outwards and upwards (fig. 270). The flaps thus Fig. 269. Fig. 270. formed are detached from their subjacent connections, and the whole raised upwards, so that the original triangular incision comes into a horizontal line, and is made to constitute the margin of the new lip; the secondary incisions under the jaw coming together in a vertical direction, in which they are re- tained by twisted and interrupted sutures. Fig. 271. BLEPHAROPLASTIC OPERATIONS. Blepharoplasty, or the operation by which the eyelids are repaired, is occa- sionally required for loss of substance,—the result of wounds, cicatrices, or ope- rations. It is less satisfactory in its results than most of the other plastic pro- cedures about the face; but yet may, in some cases, improve materially the patient's appearance. When the upper eyelid requires repair, the flap is taken from the forehead; when it is the lower lid, from the cheek or temple. This operation may be performed either by the gliding method, or by twisting a flap into its new situation. When by the gliding method, a triangular flap is cut and partially detached (fig. 271 a), and then drawn gently forwards until it corresponds to and fills up the gap that requires repair, when it is there fixed by a few points of suture. When the twisting method is employed, an oval flap is detached (fig. 271 b), except its pedicle, and twisted down, to be planted on the raw surface. Occasionally neither of these methods (fig. 272) is applicable, and then the procedure, that was successfully adopted in a case of which the annexed cut is a representation, may be adopted. Here there was a deep and hard cicatrix across the lower eyelid, causing eversion of its outer portion, and adhesion of the inner part to the ball of'the eye. After dividing the adhesions and removing the cicatrix, I made a semilunar incision so as to dissect up the eyelid, and then fixed it by points of suture in its new situation, where it became firmly adherent (fig. 273). Operations of various kinds are frequently performed on the eyelids that are truly of a plastic character. ^^mnroggS^^ BLEPH AROPL ASTIC OPERATIONS. 701 Thus in Symblepharon, or adhesion between the lid and the eye-ball, the adherent portion of lid may be included between V shaped incisions removed and the edges of the cuts brought together (fig. 274 a). Fig. 272. Fig. 273. In Epicanthis, or the projection of the nasal fold of the eyelids, an elliptical portion may be removed parallel to the nose, and the edges of Fig. 274. the incision brought together with sutures. In Ptosis, or drooping of the upper eyelid, an oval portion of the lid may be raised horizon- tally, and removed so as to leave an oval gap (fig. 274 b), the edges of which being brought together will lessen the depth of the lid, and thus diminish the deformity. In Entropium, or inversion of the eyelid, the same operation may be prac- tised on it, and thus, by the contraction of the cicatrix, the tendency to its turning inwards lessened. But various other procedures are at times required in order to remedy this deformity. Thus a Fig. 275. vertical instead of a transverse flap may be removed; or Crampton's plan may be followed, which consists in making a vertical incision through the whole thickness of the lid, near either angle (fig. 275 a), and then removing a transverse fold of tbe skin, bringing the edges of that wound together in the usual way. This operation is chiefly applicable when the tarsal cartilage is contracted and shortened as it were; or lastly, when the tarsal cartilage is much contracted and in- verted, the whole edge of the lid may be removed by passing a Beer's spatula between it and the ball, and then cutting upon it. In Ectropium, or eversion, the lid may be well everted and a portion of the conjunctiva raised with a pair of forceps and snipped off. This operation sel- dom succeeds however; and it is usually better to remove a wedge-shaped por- tion of the lid, of size proportioned to the amount of eversion; or Dieffenbach's method may be tried, which consists in making a transverse incision through the lid down to the conjunctiva, seizing this, drawing it forwards until the lid is restored to its proper shape, then removing the projecting fold and bringing the edges of the incision together in tbe usual way (fig. 275 b). Besides these more regular plastic operations, various other procedures may be required for the restoration of deformities of the face, in which the surgeon 702 PLASTIC SURGERY OF THE FACE. may display much ingenuity and benefit his patient greatly. The annexed cuts (figs. 276, 277) represent a case lately under my care, before and the day after Fig. 276. Fig. 277. operation, in which there was a large aperture by the side of the nose, with loss of the bones of the nasal fossae, that was successfully closed by a flap of skin taken from the forehead. DISEASES OF THE TONGUE. Infants and even adults are said to be tongue-tied, when the frenum linguaa is shorter than usual, causing the end of the tongue to be depressed and fixed, so that it cannot be protruded beyond the incisors. If this malformation be considerable, suckling and distinct articulation may be interfered with, and then division of the fold becomes necessary, which may readily be done by snipping it across with a pair of round-ended scissors. In this little operation, the risk of wounding the ranine arteries that is sometimes spoken of, may be avoided by keeping tbe point of the scissors downwards towards the floor of the mouth. Prolapsus of the tongue has occasionally been met with, either as a congenital or an acquired condition; it has been described by Lassus and Crosse as con- sisting either in a want of power in the retractor muscles or in hypertrophy of that organ. In this condition, the tongue lolls out of the mouth, is greatly swollen, of a purplish color, but somewhat dry, with constant dribbling of saliva. If the swelling have existed for a long time, it may give rise to de- formity of the teeth, and of the alveolus of the lower jaw, which is pushed forwards. In the treatment of this affection, little can be done unless it be excessive and of a permanent character, when excision of a portion of the tongue by knife or ligature may be required. In children, the ligature would certainly be the safest, as excision might be followed by abundant hemorrhage, not very easy to arrest. Glossitis is a rare affection, more particularly when occurring idiopathically; most commonly it results from profuse and injudicious salivation. In this dis- ease the tongue is greatly infiltrated with serum and blood, becoming immensely swollen, so as to hang out of the mouth, with profuse salivation and inability on the part of the patient to swallow or speak, with perhaps a threatening of suffocation. The treatment is as simple as it is efficient; it consists in making DISEASES OF THE TONGUE. 703 a long and free incision along the dorsum of the tongue on either side of the raphe, which gives free and immediate relief by the escape of the blood and infiltrated fluids. I have seen a patient, who was nearly suffocated by the im- mense size of his tongue, relieved at once, and get nearly well in the course of a few hours by such incisions. Purgatives, especially of a saline character, are also useful, but these cannot be administered until after the swelling has been relieved in the way just mentioned. Abscess of the tongue, though rare, occasionally occurs. A boy was brought to me some time ago with an elastic fluctuating tumor of slow growth, and about the size of a small plum, situated deeply in the centre of the tongue; on puncturing it, about half an ounce of healthy pus was let out, after which the cyst speedily closed. The epidermic covering of the tongue may become the seat of various morbid changes; amongst the most remarkable of which is psoriasis. In this affection the tongue is indurated, shrivelled and dry, having cracks upon its surface, with patches of a dead-white color, and irregular shape, varying in size from that of a split-pea to an inch in diameter; this condition exactly resembling psoriasis of the palms of the hands, may occur with or without scaly disease of the general integument. I have seen it in both conditions, and have always found it a most difficult affection to treat. The preparations of arsenic with Plummer's pill and sarsaparilla, have, however, appeared to afford the best results. In some instances, it is evidently of syphilitic origin, and then it requires to be treated on the general principles that guide us in the manage- ment of the constitutional forms of that disease. The surface of the tongue occasionally assumes a glazed and warty character, as if covered with a layer of boiled sago, the mucous membrane being cedema- tous, elevated, and papillated, but at the same time glassy and semi-transparent, and without induration. This condition, which is usually of syphilitic origin, requires the constitutional treatment for that disease. Fissures or cracks not uncommonly appear upon the side of the tongue, usually opposite the molar teeth, sometimes dependent on irritation of stumps, but not unfrequently on dyspepsia. These cracks may in some depraved states of the constitution extend rapidly, eroding away a considerable portion of the side of the organ in a short time, so as to leave a large and deep sloughy cavity with much dusky inflammation around it, with great fetor of the breath, and a copious discharge of saliva which trickles out of the corners of the mouth; the patient being usually destroyed in from three to six months, by the irri- tation of the discharges, the inability to take food, and the supervention of hemorrhage. This disease, which is a combination of sloughing and ulceration, is best treated in the early stages by the application of leeches beneath the jaw, and the use of chlorinated gargles, with a moderately antiphlogistic regimen; as it advances, the internal administration of arsenic is useful in some cases, with the application of the balsam of Peru, either pure or diluted with the yelk of egg, and the employment of gargles composed of the chlorides and the tinc- ture of myrrh. Syphilitic tubercle is not unfrequently met with in the tongue, as one of the advanced symptoms of constitutional syphilis, forming an indurated irregularly circumscribed mass, of a round shape, situated deeply in the substance of the organ, or toward the centre of the tip. The surface covering the tubercle is of a dusky red or coppery color; it rarely runs on to ulceration, though rhagades and fissures occasionally form around it; there is no fetid discharge and no destruction of the organ in these cases. The treatment consists in the adminis- tration of small doses of bichloride of mercury in sarsaparilla, under which it will rapidly disappear. Various cancerous and cancroid diseases may occur in the tongue. These affections usually commence with tubercles, or fissures, or as a solid mass in 704 DISEASES OF THE TONGUE. the body of the organ; most commonly the disease is situated at the sides, but occasionally the tip is affected. If as a tubercle or warty growth, it is usually flat, indurated, and of a purplish-red color, gradually running into ulceration; if with a fissure, this from the commencement has an indurated base, a foul surface, and an everted edge. As the ulceration extends, a chasm with ragged sides, a sloughy surface that cannot be cleansed, and a widely indurated base, gradually forms; there is great fetor of the breath, profuse salivation, and as the disease progresses, implication of the mucous membrane and of the struc- tures of the floor of the mouth, and of the submaxillary or sublingual glands, takes place. The lymphatic glands under the jaw usually become involved at an early period, but I have known the disease exist for a year or two without their becoming implicated. Cachexy at last supervenes, and the patient dies from the conjoined effects of exhaustion, irritation, and poisoning of the system. In the majority of instances, the disease assumes a cancroid form, but tumors of the tongue may occasionally occur, presenting all the characters of scirrhus. In one instance I have seen cancer of the tongue assume a truly encephaloid character; it was a case in which the disease had twice been removed, and recur- ring a third time, assumed the character of a large, soft, fungating growth, with rapid implication of the floor of the mouth and maxillary glands, death speedily occurring from exhaustion. The diagnosis of these various forms of disease of the tongue is important. The foul and sloughing ulcer may be distinguished from all others by the rapidity of its progress, its eroding action, and the absence of all induration at its base. Syphilitic ulceration, with an indurated base, commonly closely resembles cancer of the tongue; so closely indeed, that it is only with great difficulty that the diagnosis can be effected. This, however, may generally be accomplished after a time, by observing that the syphilitic ulcer is elongated, irregular, and does not rapidly extend; the cancerous ulcer on the other hand is of a circular shape, has eroded edges, and spreads with considerable rapidity. The influence also of treatment will after a time throw light upon the nature of the disease, and the scrapings of the cancerous ulcer when examined under the microscope, will always reveal its true character. The diagnosis between the syphilitic and cancerous tubercle is most impor- tant; here the duration of the disease and the co-existence of constitutional syphilis must be taken into account. It is also of much moment to attend to the situation of the tumor, the syphilitic tubercle being almost invariably met with deeply in the substance of the organ, whilst the cancerous growth is com- monly seated at its edges or tip. In the treatment of cancer of the tongue therapeutic means are utterly use- less ; and no measures hold out any chance of recovery to the patient except the removal of the diseased structure. This may be effected either by the ligature or the knife, and should be done as early as possible, before glandular or constitutional infection has come on. When the free portion of .the tongue only is diseased the morbid structure may readily and safely be excised; any hemorrhage that ensues being arrested by the ligature of the bleeding points, or by the introduction of ice into the mouth. When the organ is more exten- sively diseased it has been proposed to divide the lower jaw, and thus to get a view of the whole of the tongue, and to remove as much as proper, treating afterwards the section in the bone as a fracture of it. When, however, the tongue is very deeply diseased excision is objectionable, as the hemorrhage that follows may be so considerable as to be stopped with difficulty, and, indeed, to require the application of the actual cautery for its arrest. In these deep can- cerous affections of the tongue also, there is usually great enlargement of the submaxillary glands, with infiltration of the floor of the mouth and of the neighboring soft parts to such an extent as to render it impossible with safety or advantage to excise the diseased mass. OPERATIONS FOR CANCER OF THE TONGUE. 705 The ligature is the plan usually had recourse to, and which, indeed, I think, is in all cases, except where the tip is alone involved, preferable to excision; but though there is no risk of hemorrhage when this means is used, yet it is not without objection on account of the painful nature of the process and its tediousness. Mr. Hilton has removed the first objection by proposing and prac- tising the section of the gustatory nerve prior to the application of the ligatures. This operation may be done by drawing the tongue forwards and dividing the mucous membrane and submucous tissue vertically for three quarters of an inch, opposite the molar teeth, over the hyoglossus muscle, and across the upper por- tion of the sublingual gland; much venous bleeding usually occurs, which embarrasses the search for the nerve, yet with a little dissection this may be exposed and divided, when sensation will cease in the whole of that portion of the tongue which is anterior to the line of incision. By means of the ligature any portion of the tongue, however deeply seated, may be securely strangled. For the purposes of this operation strong thick saddler's whipcord is the best, as it does not readily cut through the soft and brittle tissue of the organ, as would be the case if the small compressed cord usually sold by the instrument- makers is used. In removing cancer of the tongue by ligature, the patient should be conve- niently seated opposite a strong light. The surgeon then passes a strong silk thread doubled, through the tip of the tongue, by which an Fig. 278. assistant draws the organ out of the mouth; a wooden wedge is next placed between the teeth of the upper and lower jaws, on the side opposite to that on which the operation is to be per- formed, and the ligature is then passed by means of an ordinary nevus needle, or what is often more convenient, a corkscrew needle curved on the side as well as to the point (fig. 278). In many cases the plan described for ligaturing fiat nevi will be found the most convenient mode of passing the whipcord round the cancer of the tongue (fig. 279). In whatever way the ligatures are applied, care should always be taken to pass them through the healthy tissue of the organ wide of the disease, and they should then be tied very tightly, so as to strangle the Fig. 279. 8 mass effectually. Great swelling of the tongue, followed by profuse salivation and some fetor of the breath attend this operation, but the mass, if properly constricted, will slough away in a few days, leaving a large gap that readily fills by granulation. When the disease exists so far back in the tongue that it cannot readily be reached from the mouth, Cloquet, Arnott, and others have successfully strangled it by making an incision in the hyoid region, between the genio-hyoid muscles, forcing the ligatures by means of long needles through the base of the tongue, and then drawing them tight through the aperture in the neck, so as effectually to constrict the diseased mass. 45 706 DISEASES OF THE TONGUE. Regnoli has successfully extirpated large portions of the tongue for cancerous disease of the back of the organ, by making an incision of a semi-lunar shape, along the line of the lower jaw from one angle of the bone to the other, thus opening into the cavity of the mouth through its floor, then making a vertical cut through the centre of this, from the os hyoides forwards, clearing the parts by a little dissection, and drawing the tongue through the opening down upon the anterior part of the neck, where the diseased structures may be ligatured or excised (fig. 280). The wound is then closed and united in the usual way. By this means the surgeon can reach portions of the organ that cannot be got at in any other way. The ecraseur has been successfully used by Chassaignac in removing tumors of the tongue that could not otherwise be extirpated. In such operations two Fig. 280. Fig. 281. or more instruments are commonly required, which, as Chassaignac represents (fig. 281), must be passed through the substance of the tongue in opposite directions, so as to isolate and detach the diseased portion of the organ. When, however, the floor of the mouth is implicated in the morbid action, nothing should, I think, be attempted, as it is impossible to extirpate the whole of the disease, and partial removal of it will only be followed by rapid recur- rence and increased activity of development. I do not think that the enlarge- ment of the submaxillary glands merely should be any bar to the operation, provided the disease be limited, and the constitution good, as under these circumstances the glands may be excised, as well as the disease of the tongue removed; or, if they be not of any very considerable size, they may be left, when they will perhaps subside without the necessity of operation, as their enlargement may probably be dependent upon simple irritation; or should they continue indurated, they may readily be removed at a subsequent period. Tumors of various kinds, encysted, fatty, and erectile, are met with in the tongue, and underneath it in the floor of the mouth. They require extirpation by the ligature, or enucleation with the handle of the scalpel or fingers, accord- ing to their situation and size, and for these irregular operations no special directions can be given. In removing such tumors as these, when situated under or by the side of the tongue, the knife must necessarily be used with much caution. It must, however, be borne in mind, that if these growths cannot be reached from the inside of the mouth, they may be got at by incision through OPERATIONS FOR CANCER OF THE TONGUE. 707 Fig. 282. the mylo-hyoid region, where there is but a slight thickness of soft parts between the surface and floor of the mouth. Ranula is perhaps the most remarkable of these buccal tumors. This disease occurs under two forms; 1st, as a globular swelling, semi-transparent, evi- dently containing fluid, and often attaining the size of a walnut or pigeon's egg, situated under the tono-ue, pushing this organ upwards and backwards, and consequently interfering with deglutition and speech (fig. 282). The walls of the cyst are usually thin, with small vessels ramifying on them; its contents are glairy and serous. This form of ranula is usually said to be a dilatation of Wharton's duct; but it certainly appears to me that there is no proof of the disease being of this nature, and, in- deed, it is not very easy to understand how so small a duct can be dilated to so large a size as is occa- sionally attained by these tumors, which seem, in some cases at least, rather to consist of distinct cystic formations such as commonly occur in connection with other secreting glands. The treatment of this form of ranula consists either in passing a seton through its walls, so that contraction may take place on this, or else in the excision of a large portion of the anterior wall of the cyst, the remainder contracting, until it at last becomes obliterated. 2d, Besides the ordinary form of ranula, an encysted tumor, partaking ot tnis character, is occasionally met with, lying above the mylo-hyoid muscle, between it and the buccal mucous membrane, projecting, however, more distinctly into the neck than into the mouth; occupying, perhaps, all the space between the lower jaw and the os hyoides on one side, and attaining the size of an orange. In a case of this kind in a lad of twenty, lately under my care, the contents of the tumor, which closely resembled cream cheese in character, were found to be composed of well-formed epithelial scales and much fatty matter. Such tumors are, I think, best treated by having a free opening made into them from the mouth, their contents squeezed or spooned out, and the cavity being stuffed with lint allowed to granulate and contract. If an attempt be made to extirpate them from without, the profuse and perhaps dangerous hemorrhage, the firmness with which the cyst wall is incorporated with surrounding parts, the danger attendant on the free use of the knife in the neighborhood of such important parts as lie between the mylo-hyoid muscle and the base of the tongue, will render such an operation not only an unsatisfactory, but a hazardous procedure. 708 DISEASES OF THE JAWS. CHAPTER L. DISEASES OF THE JAWS. DISEASES OF THE GUMS. Abscess of the gums is of very frequent occurrence, from the inflammation of decayed teeth. Here a free and early incision should be made, which, by giving exit to the pus, will afford immediate relief. Spongy and sloughy ulceration of the gums will occur as the result of consti- tutional cachexy in anyway induced — by mercury, Fig. 283. malaria, syphilis, &c. They are best treated by tonics, in conjunction with the chlorate of potass and mineral acids internally. If spreading actively, escharotics, such as the muriatic acid or creosote, may be advan- tageously applied. If not making much progress, a solution of the nitrate of silver, with chlorinated or tannin gargles, will be useful. Epulis is a tumor of a fibrous character, springing from the periosteum and edge of the alveolus, and im- plicating the osseous walls, growing up between, and loosening the neigboring teeth, which it displaces and envelopes in its structure. It is most frequently met with in the lower jaw. and commonly about the molar teeth (fig. 283). This tumor is red, smooth, and lobulated, at first hard and semi-elastic, like the ordinary structure of the gum, but after a time softening by disintegration, and ulcerating on the surface, with a purulent or sanious dis- charge; it appears simply to be a circumscribed hypertrophy of the gum. Tbe treatment of epulis consists in the removal of the whole of the mass and of that portion of the alveolus from which it springs. As it evinces a great tendency to reproduction, it must not simply be shaved off the bones, but a portion of the osseous structure must be removed as well; unless this point be attended to, the growth will to a certainty be reproduced. In performing the operation, the first thing to be done is to extract a tooth contiguous to and on either side of the tumor; a cut must then be made with a saw through the alveoli of the teeth that have been removed, down to a level with the base of the growth. In doing this care must be taken not to cut too near the remain- ing teeth, lest the alveoli be opened and their support lost. If the tumor is large it may be necessary to saw deeply, but the base of the lower jaw should in all cases be left intact, the whole of its substance not being sawn through, so that, though a considerable portion of bone be removed, yet the length of the jaw may be preserved. For this purpose Hey's saw should not be used, it is a higgling instrument, difficult to manage in this situation; but a straight and stiff-backed saw, with as deep a blade as the mouth will conveniently admit, will be found most useful (fig. 209). The epulis, included between two vertical cuts, may now be removed with cross-cutting forceps, and the bleeding stopped by placing a plug in the wound and compressing it against the teeth of the upper jaw by means of a bandage passed under the chin. Should there be a spouting dental artery, it may be necessary to apply a red-hot wire in order to arrest its bleeding. The cut surface will speedily granulate, and the cavity fills up with fibrous tissue. Cancerous ulcers and fungous growths from the alveolar processes, malignant epulis, as they are called, occur in the same way as the last; but they are soft, DISEASES OF THE ANTRUM AND UPPER JAW. 709 purplish, very vascular, grow rapidly, and are speedily reproduced after removal; they principally, I think, occur in males advanced in life. The same operation requires to be practised for these diseases as for the simple epulis, and as there is usually much hemorrhage following their removal, a red-hot iron must be applied to the bleeding surface. DISEASES OF THE ANTRUM AND UPPER JAW. Our present knowledge of diseases of the jaws, and of the operative procedures necessary for their removal, is chiefly due to the labors of Gensoul and of Liston. Mr. O'Shaughnessy also, who appears to have had many opportunities of wit- nessing these affections amongst the natives of India, has added much to our acquaintance with their pathology and treatment. The antrum may be the seat of fluid accumulations or of solid tumors. Dropsy of the antrum from accumulation of mucus within this cavity occasion- ally occurs. As the aperture leading from this cavity into the nose is a little above its floor, there may be a natural tendency for the fluid secreted here to accumulate to some extent before it is discharged. If, however, this aperture be from any cause blocked up, the secretion may increase to so great a degree as to occasion serious inconvenience by its outward pressure. In cases such as these, the accumulation of fluid has been known after a time to expand the walls of the cavity; and in this way the floor of the orbit or the roof of the mouth may be caused to bulge, the nasal cavity may be encroached upon, and the cheek rendered round and prominent — an indolent semi-elastic tumor forming in it and protruding it outwards, and giving rise to the egg-shell or parchment crackling on pressure. The treatment in these cases consists in making an opening into the cavity of the antrum with a strong perforator through its most expanded and thinnest part, and leaving a plug of lint in the aperture, so as to allow the discharge to escape freely. The shape of the cheek may be restored by the gradual pressure of a spring pad or double-headed roller. Suppuration may take place in the antrum, being usually excited by the irritation of a carious molar tooth, or by some injury of the face, and occasioning perhaps much pain, with throbbing or lancinating sensations. The pus, as it forms, will sometimes overflow, as it were, into the nose through the aperture between these cavities, and then may keep up constant irritation, with much fetor in the nostrils; in other cases, it drains through the socket of a tooth into the mouth; and in other instances again, its exit being prevented, it gives rise to enlargement of the cheek, the soft parts of which become brawny and inflamed, and the bones expanded, so that at last they are thinned to such an extent, that, as in dropsy of the cavity, they crackle when pressed upon. Any portion of the wall of the cavity —the orbital, buccal, palatal, or nasal—may thus be expanded and fluctuation be felt through it, and the lachrymal duct being com- monly obstructed, the eye on the affected side becomes watery. The treatment of this condition consists in the extraction of any carious tooth seated in the neighborhood of the antrum, or if they be all sound, in the removal of the second molar, the fangs of which come in close relation to, and frequently perforate the bottom of the cavity. In this way an exit should be given to the matter; but as it will not discharge itself sufficiently freely, the antrum must be opened through the alveolus, or through the canine fossa under the cheek, provided it be much expanded in this situation, so that its cavity is easily reached. The perforation into the antrum may readily be made, or the socket of the tooth enlarged, by means of a triangular antrum-perforator, such as here repre- sented (fi°\ 284). As the matter draws away, the cavity will gradually contract, and the deformity thus be removed. It is well not to attempt 710 DISEASES OF THE JAWS. to perforate in the site of teeth that have been extracted for some length of time, as here the bone becomes unduly consolidated, and I have consequently seen failures in reaching the cavity occur. The matter that is discharged is often very offensive, or it may be thick and pasty from the absorption of its watery parts. After the aperture has been made, the cavity should be syringed out with tepid water, and its shape gradually restored by pressure. Tumors of various kinds spring from the upper jaw, taking their origin either from its surface, from the interior of the antrum, or from the pterygo-axillary fossa. Those that grow from the surface of the bone, are either some of the various forms of epulis that spring from its alveolar border, and must be treated as already described, or they are exostoses growing from the outer surface of the bone, projecting perhaps up into the orbit, and requiring removal with the saw, bone-nippers, or gouge. In doing this, care must be taken not to destroy the nasal process of the bone, lest the lachrymal sac be opened. The tumors that spring from the cavity of the antrum or from the posterior part of the upper jaw are of very various kinds;—fibrous, cartilaginous, osseous, fatty, fibro-plastic, erectile, and encephaloid growths may all be met with in this situation. In the Museum of University College, which is very rich in specimens of these tumors, most of the above varieties will be found. The fibrous tumor is perhaps the most common; it principally occurs in elderly people, and may attain a very considerable bulk. The encephaloid comes next in order of frequency, and the osseous and enchondromatous occur, but are ex- tremely rare. The osseous tumors are remarkable as occasionally appearing to set up a spontaneous attempt at elimination, by necrosis taking place in them. These various growths are most commonly connected with, or spring from, the mucous membrane of the antrum, and in growing gradually expand and dilate the walls of this cavity, pressing the bone outwards, thinning them, and giving rise to a considerable outward projection of one side of the face. The tumor thus formed is usually smooth, round, or oval, slightly lobed perhaps, more especially if of a fibrous character, and has in many cases a ten- dency to hang downwards so as to overlap the lower jaw to a certain extent; at the same time it encroaches more or less upon the other cavities lying in the vicinity of the antrum. Thus, it pushes down the palate, causing considerable swelling in the roof of the mouth; displaces the alveolar processes and teeth, giving rise to irregularity in their outline; and when encroaching upon the orbit, occasioning stillicidium lachrymarum, or even impairment of vision. As the tumor enlarges, it obstructs the nasal cavity, and stretching back into the pharynx, interferes with respiration and deglutition. When it is of an ence- phaloid character, obstruction of the nasal fossa will be found to be one of its earliest signs; and the integuments will be observed speedily to become in- volved, the gums implicated, and the submaxillary absorbent glands enlarged. In the diagnosis of these tumors there are three principal points to be at- tended to: — 1st, to distinguish them from fluid accumulations; 2d, to deter- mine whether the growth is simple or malignant; and, 3d, to ascertain its seat. In making the diagnosis from fluid accumulations in the antrum, the history of the case, and the uniform enlargement of the cavity without the tumor project- ing externally beyond any part of its walls, may enable the surgeon to deter- mine that it is not of a solid character. But in many cases this is not sufficient, and it becomes necessary to have recourse to an exploratory puncture by means of the perforator, through one or other of the more thinned and expanded parts already indicated. This should never be omitted in cases of doubt, for it has happened even to so good a surgeon as Gensoul, that after making incisions through the cheek with the view of extirpating the tumor, the bones were found to be expanded by an antral abscess, and that, consequently, the opera- tion had been undertaken unnecessarily. In determining whether the growth be of a simple or malignant character, TUMORS OF THE ANTRUM. 711 the surgeon will experience much difficulty, so long as it is confined to the cavity of the antrum; but when once it has perforated and got beyond its walls, this point is easily solved. Whilst the tumor is still confined within the antrum, much light may however be thrown upon its nature by attention to the rapidity of its growth; the greater this is, the more reason there is to suspect its malig- nant character. But though attention to this sign is of value, yet too much importance must not be attached to it; for though as a general rule, the fibrous and cartilaginous tumors may increase less rapidly than the malignant, yet it may happen that these attain a very great bulk in a short space of time. With regard to the age of the patient, that is of comparatively little value in a diag- nostic point of view. I think, however, that as a general rule, simple tumors most frequently occur in the young, whilst the malignant forms of the affection are commonly met with at the middle or advanced periods of life. It is of much importance, even in a diagnostic point of view, to examine the condition of the submaxillary glands. When the disease is malignant, they become en- larged and indurated, at a very early period. In a case lately under my care, the malignant character of a tumor whilst still in the antrum, was determined by the fact of there being a long chain of indurated lymphatic glands, lying under the angle of the lower jaw, where they had become secondarily affected by absorption, before the bones had been perforated by the growth. When once a malignant tumor has got beyond the cavity of the antrum, and is thus relieved from the pressure of its walls, it grows with great rapidity, insinuating itself extensively amongst the bones of the face and skull, by creeping through the foramina and fissures, encroaching greatly on the nasal cavity and orbit; im- plicating the integuments of the cheek and soft structures within the mouth; and throwing out sprouting masses in these several situations, which present all the characters of the true malignant fungus. A point of very great importance in relation to operative interference is to determine whether the tumor springs from the cavity of the antrum, or takes its origin behind the superior maxilla in the pterygo-maxillary fossa. In the former case, the nasal or palatal walls of the antrum are expanded, and the line of teeth rendered irregular. In the latter, the maxillary bone will be found to be simply pushed bodily forwards, there being little if any deformity in its outline, the line of teeth not being displaced, or the walls of the antrum, — palatal, nasal, or orbital, expanded. Yet it must be borne in mind that the difficulty of the diagnosis is greatly increased by the fact that a tumor, though not originating in the antrum, may pass into the orbit, through the spheno- maxillary fissure, and may make its way forwards amongst the bones of the face, partly by creeping through, and partly by displacing them. In the treatment of tumors of the antrum, nothing can be done except to extirpate the growth; and it is consequently of great importance to distin- guish those forms of the disease in which an operation can be undertaken with safety, and with a fair chance of success, from those in which none should be performed. When the tumor, springing from the antrum, is of a simple character, the disease should be removed, together with the whole of the supe- rior maxilla, the tumor, whatever size it has attained, being generally encysted, and the bones expanded around it; so that it is well bounded, and does not im- plicate neighboring parts. Here, as Liston justly observes, no nibbling or grub- bing operations should be done, but free excision of the whole mass practised. When the tumor springs from the pterygo-maxillary fossa pushing the bones of the side of the face forwards, I think it is doubtful whether the surgeon ou°-ht to interfere, as the base of the skull may be implicated to such an extent that the patient may die a few hours after the operation, as I saw happen in a case of Listen's. When once a malignant growth of this part has passed beyond the osseous boundaries of the antrum, it should not be interfered with. So Ion"- as it is contained within this cavity, where indeed it is often impossible 712 DISEASES OF THE JAWS. to ascertain, until after removal, the true nature of the affection, it may be excised, provided the glands in the neck be not greatly enlarged. If they are much implicated, even though the walls of the antrum be not perforated, I think it is safer not to interfere, as a cure by operative procedure must be hope- less. Whenever the soft structures of the cheek are involved so as to require partial excision with the tumor, no operation should be performed, as the dis- ease will probably have become constitutional, cannot be completely extirpated, and will speedily recur in the cicatrix. The operation of the excision of the upper jaw together with the malar bone for tumor of the antrum, was first proposed by Lizars in 1826, though Gensoul of Lyons was the first surgeon by whom the operation was actually performed, in May, 1829. It may conveniently be done in the following way: The central incisor on the diseased side having been extracted, the point of a bistoury should be entered opposite the external angular process of the frontal bone, and carried with a semi-circular sweep into the angle of the mouth. From the upper end of this incision, a cut about one inch in length may be carried along the zygoma. Another incision is made from the nasal process of the superior maxillary bone, down to the side of the nose, round the ala, which it detaches, and through the centre of the upper lip into the mouth. The flap thus formed is dissected upwards until the margin of the orbit is reached, the soft parts are then carefully separated from the floor of this cavity, and the infra-orbital nerve dissected and drawn upwards with a curved copper spatula, which protects them and the globe of the eye. The next step in the operation consists in the division of the bones. This may best be done with strong cutting pliers; the zygoma should be first cut across, the external orbital angle next divided, and then the internal angle cut through by putting one blade of the forceps into the nostril and the other into the orbit. The palatal arch must next be cut across by notching it deeply with a Hey's, or a narrow-bladed saw, and then passing the pliers into the mouth and nose, cutting through the line of the groove and the alveolus of the incisor that had been extracted. The whole mass having thus had its osseous connections separated, is depressed, drawn forwards, and readily removed by breaking down adhesions with the finger, or with the bistoury by the division of a few remaining soft parts. In the early stage of the operation, during the incisions through the cheek, there is often a good deal of hemorrhage; this may be arrested by pressure, or by the ligature of any vessels, such as the facial, or transverse fascial, that bleed with great activity, and if necessary by the application of the actual cautery to the bones. However much the soft parts may be stretched no skin should ever be removed, as it will all eventually contract. In the later stage of the operation after the removal of the tumor there is not so much hemorrhage as might be expected, though some branches of the internal maxillary will require ligature. By an operation such as this, the whole of the superior maxillary and malar bones may, if necessary, be removed, and the large cavity that is left between the eye and mouth, having some lint introduced into the bottom so as to support the parts in the orbit and the cheek, may be allowed to granulate; the cheek being replaced and retained in situ by a few points of twisted suture evenly introduced through the line of incision in it, and in the upper lip. After cicatrization is complete, the deformity resulting from such a procedure will be far less than might at first be anticipated. In some cases the malar bone and floor of the orbit will be found to be sound. When this is the case they should both be left, and with this view, after the cheek has been turned up, as just described, a deep groove should be made with a narrow, straight-backed saw, below the orbit directly across from the nasal process of the maxillary, and the outer edge of the malar bones. The removal of the growth may now be effected by cutting through the nasal process DISEASES OF THE LOWER JAW. 713 with the forceps, and then applying them to the horizontal groove made below the orbit, after which the palatal arch may be divided as already directed. Mr. Fergusson has in some cases succeeded in removing tumors of considerable magnitude by a single incision through the cheek, from the angle of the mouth upwards and outwards; and in other cases by slitting open the upper lip in the mesial line, and then carrying the knife along the side of the base of the columna into the nostrils, by which simple incision this distinguished surgeon has shown, that sufficient relaxation of parts can be obtained to excise the greater portion of the superior maxillary bone. DISEASES OF THE LOWER JAW. The lower jaw is not unfrequently the seat of necrosis, which may arise either from some constitutional cause, from local injury or irritation, or from the specific action of the fumes of phosphorus. In this disease we must wait until the bone has become loosened, and then by incisions through the gum, or through the structures of the lower part of the cheek, or under and along the lower angle of the jaw, reach the diseased bone and extract this; separating, if necessary, any part that may still be adherent by means of cutting pliers. Tumors not unfrequently spring from the lower jaw. Like those in the superior maxilla they may either be simple or malignant. Amongst the simple, we most commonly find the fibro-cystic. Fibrous tumors are also occasionally met with, and more rarely osseous and enchondromatous growths. The malig- nant tumors are principally of an encephaloid character. These various growths frequently occur in early and middle life, and usually spring from the diploe, between the two tables of which the bone is composed. They project into the mouth and on to the side of the neck, forming large rounded uniform, or imperfectly lobed masses. Occasionally malignant diseases spring from the neighborhood of the bone, and, without invading its structure, envelope it so as to give rise to an appearance of morbid implication of it. Epulis not unfrequently springs from the alveoli of the lower jaw; however large this may be, it is always a disease of the alveoli, and can implicate the bone only by extension to it. It is usually sufficient to remove the mass with the alveoli from which it grows, the base of the bone being left, which is a great advantage, as it prevents shortening of the jaw. Operation. — Extract the tooth on either side of the growth, cut with Hey's saw down the alveolus on either side, then make a cross-cut under the tumor into the bone with the saw, and next apply cross-cutting forceps so as to remove it. In the cystic and fibro-cystic tumor of the jaw the growth is expanded into cysts having more or less solid matter intermixed, partaking of the character of epulis. These cysts are of various degrees of thickness; some being thin and membranous, others having the walls partly composed of fibrous tissue, and others again having expanded bony lamellae largely entering into their compo- sition, so that on pressure they occasionally communicate the semi-crepitant sensations peculiar to the cystic expansions of the osseous structure. The fluid contained in these cysts is a viscid liquid, usually semi-transparent, yellowish, or bloody. In the lower, as in the upper jaw, it is of great importance to diagnose the simple from the malignant affections, as in the latter form of disease an opera- tion is rarely justifiable, the soft tissues around the bone being usually impli- cated to such an extent as not to admit of removal, and consequently of the full and complete extirpation of the disease. The malignant tumors may generally be readily detected by the rapidity of their growth, their pulpy or elastic character and infiltration of neighboring parts, with implication of the sub-maxillary glands. The treatment of tumors of the lower jaw depends in a great measure upon 714 DISEASES OF THE JAWS. the character of the growth. In cystic tumors of moderate size, with thin walla and but little deposit of fibrous tissue around the cysts, the best mode of treat- ment consists in cutting down on the expanded portion of bone, opening the cyst by means of the antrum-perforator, small trephine, or cutting-pliers, accord- ing to its size and the thickness of its walls; letting out the fluid contained within, and then by introducing a plug of lint get it to granulate from the bottom, and gradually to contract. When the cysts are so large that they have destroyed the integrity of the bone, or when they are associated with a large quantity of fibrous tissue, so as to constitute true fibro-cystic tumors, excision of the diseased bone must be practised. This, also, is the only plan of treatment that can be had recourse to in other affections of this bone. The operation of excision of a portion of the lower jaw for tumor of that bone was first performed by Dupuytren. As the growths for which this operation is performed are usually situated between the symphysis and angle of the bone, seldom extending beyond the middle line, the operation is generally limited to one side of the face. In some instances, however, the tumor may encroach so far that it may be necessary to remove more than the half of the bone; and in other cases, again, though of very rare occurrence, the whole of the bone has been disarticulated. When the tumor is of small size, and is situated about midway between the symphysis and angle of the jaw, it may be reached by making a semi-lunar incision of sufficient length under the lower edge of the bone, dissecting up the flap thus formed, then carrying the knife cautiously along the inner side of the jaw, so as to detach the mucous membrane of the mouth and the mylo-hyoid muscle to a sufficient extent. One of the teeth on either side of the tumor having been previously drawn, the jaw must now be deeply notched through their alveoli into its base with a narrow strong-backed saw, and cut through with pliers. After the fragment of diseased bone, with the attached tumor, has been removed, the teeth should be tied together with strong silver wire, or a silver cap should be fitted upon the teeth of the two portions of bone that are left, and attached by an elastic spring to another silver cap put on those of the upper jaw, so as to prevent the displacement that would otherwise occur in the smaller fragment. Union takes place after a time by fibrous tissue, which be- comes sufficiently dense to make the jaw strong and useful. In those cases in which the tumor encroaches upon the angle and ramus of the jaw, it is, better to remove the bone at the articulation on the affected side, for if the articular end including the coronoid process be left, it will be displaced forwards and upwards by the action of the temporal and external pterygoid muscles, and be a source of much inconvenience and irritation to the patient, unattended by any corresponding utility. In these cases the removal of one lateral half of the jaw will consequently be required, and the operation may be performed in the fol- lowing way: — The point of a strong bistoury or scalpel should be entered im- mediately behind the articulation, carried down the posterior margin of the ramus behind the angle, and under the body of the bone beyond the anterior limits of the tumor, where it must slope gradually upwards, terminating at some distance from the lips, which should not be encroached upon; the convex flap thus formed is dissected up, and the facial artery and any other branches requiring ligature tied. The knife is then carried behind the jaw in front of the tumor, and one of the incisor teeth having been extracted before the opera- tion commenced, a saw should be applied to the bone in this situation, and its section finished by means of the cutting-pliers; the surgeon then dissects under and around it; in this situation a scalpel, curved on the flat, will be found useful, keeping the edge of the knife close to the bone and tumor. When he has cleared the tumor and ramus, he depresses the body of the bone forcibly with his left hand, in order more readily to divide the attachment of the temporal muscle to the coronoid process. This having been done, the only part left is CLEFT PALATE. 715 the disarticulation, which is best effected by opening the joint from the front, whilst the bone is well depressed and twisted somewhat outwards, the edge of the knife being kept close to its neck, scraping the bone so as, if possible, to avoid wounding the internal maxillary artery, when any remaining attachments having been cut through, the disarticulation is effected. In depressing the bone to get at the temporal muscle and the joint, care must be taken not to use too much force, lest it happen that the ramus gives way, having been weakened by the disease; a good deal of trouble being consequently experienced in removing the fragment left behind, which can only be done by seizing it with necrosis forceps, thus dragging it forwards, and then dividing the muscle and capsule. Should the internal maxillary artery have been divided, it must be ligatured, or the termination of the external carotid, where the vessel divides into the tem- poral and internal maxillary, tied : any other branches that bleed will necessarily also require the ligature; and then the cavity having been lightly filled with lint, should be left to granulate; the cheek being laid down and attached along the line of incision by hare-lip pins and twisted sutures. A kind of fibrous tissue forms in place of the jaw that has been removed, and comparatively little deformity results. When the disease of the bone extends beyond the symphysis, a thick ligature should be passed through the end of the tongue, which must be drawn forwards by an assistant, lest on the division of the insertion of its muscles into the lower jaw it be forcibly retracted into the pharynx, and thus occasion suffocation. CHAPTER LI. DISEASES OF THE THROAT. CLEFT PALATE. Various degrees of congenital deformity may occur in the palate and uvula; thus the uvula alone may be bifid, or the cleft may extend through the greater part or the whole of the soft palate; or, the hard palate may be divided as well; and, lastly, the separation may extend forwards to the integuments of the face, giving rise to the complication of hare-lip. The soft palate and uvula are most frequently cleft without the hard palate being divided; but, in some, though rare cases the lip and the hard palate are fissured without the soft one being cleft. These malformations necessarily give rise to great inconvenience, by interfering with deglutition, and rendering the speech nasal and imperfect. Durino- the swallowing of fluids, especially, there is a tendency to regurgitation through the nose, though this is occasionally prevented by the approximation of the edges of the fissure. In the treatment of these malformations, the first question to be determined is the age at which the operation should be performed. As the success of the operation depends in a great measure upon the patient remaining perfectly tranquil and steady during the necessary procedures, which are of a tedious and protracted character,—upon his assisting the surgeon by opening his mouth, and not stru°-°-ling on the introduction of the instruments, — and, after the operation in^making as little movement as possible in speech or deglutition for some day's • it is usually considered expedient not to interfere with this malfor- mation until the patient has attained the age to understand the necessity of re- maining quiet, and to be able to control his movements; but yet some recent 716 DISEASES OF THE THROAT. observations by Fergusson and Sedillot have shown that the necessary operation may be done successfully on young children. It need scarcely be remarked, that the general health ought to be in the best possible state, before any pro- cedure requiring immediate union of parts be attempted. The operation for the cure of a cleft in the soft palate may be said to have been introduced by Roux; for although several attempts at the cure of this deformity had been made by surgeons before his time, yet he was the first to establish staphyloraphy as a distinct operation. Many modifications of Roux's plan have been practised by Graefe, Warren, and others, in order to render it more easy of execution and certain in its results; but to Fergusson is due the great merit of introducing a new principle of treatment in the operation—viz., the application of myotomy to it, and thus paralyzing the movements of the muscles of the palate. Fergusson found that the great cause of failure in these cases was the mobility of the parts, and the traction exercised by the muscles, principally the levator palati, and the palato-pharyngeus on the line of union; in order to obviate this, he conceived the happy idea of dividing these muscles. Before Fergusson laid down the principles of this operation, various cuts had been made in the palate by different surgeons, with a view of taking off the tension after the sutures were tied, more especially two parallel incisions, one on either side of the line of union; these, however, were done almost at hap- hazard, and in an empirical way, without the recognition of any distinct princi- ple being involved. In the operation, as performed by Mr. Fergusson, there are four distinct stages. 1st. The muscles of the palate are divided, by passing a curved lancet- ended knife through the fissure behind the velum, midway between its attach- ment to the bones and the posterior margin, and about half-way between the velum and the end of the Eustachian tube; by cutting deeply with the point of the knife in this situation the levator palati is divided. The uvula is then seized and drawn forwards, so as to put the posterior pillar of the fauces on the stretch, which is to be snipped across, so as to divide the palato-pharyngeus. 2d. The next step in the operation consists in paring the edges of the fissure from above downwards by means of a sharp-pointed bistoury. This is best done by seizing the lower end of the uvula, putting it on the stretch, and cutting first on one side and then on the other, leaving the angle of union to be after- wards removed. The patient should then be allowed to remain quiet, and to gargle the mouth with cold water or to suck ice, so as to stop the bleeding. 3d. When this is arrested, the surgeon proceeds to the next step, that of intro- ducing the sutures; this may be done by means of a nevus needle, armed with a moderate-sized thread, being passed from below upwards on the left side of the fissure, about a quarter of an inch from the margin ; the thread should now be seized with forceps, and one end of it pulled forwards through the fissure. This may again be threaded in the needle and passed through the opposite side of the fissure from behind forwards, through the right side; as the point of the needle appears, the thread should again be seized and the needle at the same time withdrawn; the suture is then tied by means of the surgeon's knot, and in this way from two to four sutures may be passed, according to the extent of the fissure, tied lightly, and the knots cut close. In tying the knots great care should be taken that no undue traction be exercised upon the parts; in fact, the use of the sutures is not to draw, but simply to hold, the parts to- gether ; the division of the muscles has caused these to be relaxed, so that they hang down loosely and merely require to be held in apposition by the sutures. The patient must next be put to bed, and every care taken to avoid any move- ment of the palate. He should be restricted to fluid but nourishing food for a few days, and should be directed to swallow this with as little effort as possible, and indeed should not be allowed anything solid until complete union has taken place. All coughing, spitting, or swallowing of the saliva should be interdicted. DISEASES OF THE HARD PALATE AND UVULA. 717 4th. The stiches should be left in for several days, and indeed need not be dis- turbed so long as they produce no irritation. They usually require removal by the eighth or tenth day, but occasionally may be left with advantage for some time longer, until they excite irritation, or until union is perfect; they should then be cut across with scissors and drawn out, the upper one first, the middle next, and the lower one last. Should there be any aperture left in the palate, where union has not taken place, this may be closed by touching it with a point of nitrate of silver. The voice in these cases does not usually at once recover its natural tone after the operation, although in some cases it may; but at the end of a month or six weeks the patient may be put through a course of instruction with a view of regulating the movements of the tongue and the actions of the soft palate. Fissures of the hard palate are usually closed by means of " obturators" made of gold, vulcanized India-rubber, or ivory. Dr. Warren, of Boston, has pro- posed to close the fissures here by dissecting the soft tissues from the palatal arch between the margin of the cleft and the edge of the gum, and then uni- ting them in the middle line by means of stiches, in the same way as in fissured soft palate. This operation has lately been brought before the profession in this country by Mr. Pollock, who has invented some ingenious instruments for its proper performance. Mr. Pollock's operation is as follows: — An incision having been made along the edge of the cleft, at the junction of the nasal and palatal mucous mem- branes, the soft covering of the hard palate is carefully dissected or scraped down off the bones by means of curved knives, great care being taken that the mucous membrane and its subjacent fibro-cellular tissue, which varies greatly in thickness in different cases, are not perforated; when this has been well loosened on either side, it will be found to hang down as a curtain from the vault of the mouth, — the two parts coming into apposition along the mesial line, or possibly overlapping. The edges being then smoothly pared, are brought into apposition by means of a few points of suture introduced in the ordinary way and without any dragging. On this point great care is necessary. The knots having been tied, the°patient is confined to bed for several days, and on an abundant, but fluid or pulpy diet. Union will usually be found to be perfect at the end of a week. At a later period, the fissure in the soft palate, which always accompanies that in the hard, should be cleared; but it is of the greatest consequence that this be not attempted at the same time that the operation is done on the hard palate. In dividing the levator palati, Mr. Pollock adopts a different practice to that of Mr. Fergusson. Instead of cutting from behind, he passes a ligature through the curtainof the soft palate, so as to contract and draw it forwards; and then pushing a narrow-bladed knife through the soft palate to the inner side of the hamular process, by raising the handle and depressing its point, he divides readily the muscular fibres. This method of dividing the levator palati, which is analogous to the plan employed and depicted by M. Sedillot (figs. 285 to 288) appears to be more simple and easy of execution than the division of the muscles of the velum from behind. The gap that is left closes without difficulty by granulation, and seems still more to take off tension from the PaThe uvula occasionally becoming elongated, and hanging down into the pharynx so as to touch the epiglottis and sensitive mucous membranes in its neighborhood, gives rise to a tickling or spasmodic cough which can only be cured by removing the pendulous body. This little opeijation may be readily done by seizing the end of the uvula, with a pair of polypus forceps, and snip- ping across its root. Of late I have been in the habit of using a pair of "vul- 718 DISEASES OF THE THROAT. sellum scissors " (fig. 289), which I have had constructed for the purpose, by which the uvula is cut off at the same moment that it is seized, thus rendering the operation easier and less irritating to the patient. Fig. 285. Fig. 286. Fig. 287. Fio. 288. The tonsils are not unfrequently the seat of disease, becoming inflamed or permanently enlarged. When inflamed they become swollen and red, with much pain in the side of the neck and ear, increased by any attempt at swallow- ing ; there is usually rather a profuse secretion of saliva, and a good deal of swelling under the angles of the jaws; the tongue is much coated with thick Fig. 289. pasty mucus, and the voice is thick and nasal. The treatment consists in the application of leeches under the jaw, of fomentations, the inhalation of the steam of hot water, and low diet, which need scarcely be enforced, on account of the difficulty and pain in swallowing. If the mouth can be opened, much AFFECTIONS OF THE TONSILS. 719 relief may be given by scarifying the tonsils with a probe-pointed bistoury, and if abscess form, it should be opened early, which may most readily be done with a gum-lancet. The tonsils often become chronically indurated and enlarged, sometimes as the result of repeated attacks of inflammation of these parts, but in the majority of instances independent of any inflammatory mischief, though when once en- larged these organs are constantly liable to inflammatory attacks. Hypertrophy of the tonsils most commonly occurs as a strumous disease in scrofulous children, who have a tendency to congestion of the mucous membrane of the nose, and to enlargement of the lymphatic glands of the neck. In such cases as these the enlargement of the tonsils may gradually subside as the child grows older and stronger, and the treatment should be directed to the improvement of the general health and strength, by means that are ordinarily had recourse to in the management of strumous affections; the internal use of iron and the local application of the tincture of iodine or of nitrate of silver being occasionally serviceable. In the majority of instances, however, the disease will not be influenced by any therapeutic means that may be adopted; and as the enlarge- ment, continuing or increasing, gives rise to difficulty in respiration, and thus interferes with the due arterialization of the blood in the lungs, and impairs the child's speech, it becomes necessary to remove the projecting portions of the enlarged growths. This may most conveniently be done by means of the ordinary tonsil-guillotine; the ring of the instrument being passed over the tumor, the cutting blade is pushed forwards, and thus a slice of the projecting part of the growth is removed. In some cases not a little difficulty is experi- enced in getting the tonsil fairly into the ring of the instrument, more particu- larly if the child is unruly; this may be obviated by drawing it through with a vulsellum or double hook, and indeed in some of the machines sold for the pur- pose a kind of prong is attached, which being fixed into, draws forwards the tonsils before it is sliced off (fig. 290). In performing this operation, especially Fig. 290. in children, it is most convenient for the surgeon to stand behind the patient, as he can thus look better into his mouth and has more command over the head. Should a guillotine not be at hand, the tonsil may be removed by seiz- ing it with a vulsellum, drawing it forwards, and then taking off a slice with a probe-pointed bistoury, the base of the blade of which should be wrapped round with a piece of plaster, to prevent its wounding the tongue. In excising the tonsil in this way, care must be taken to cut downwards and inwards towards the mesial line, and on no account to turn the edge of the knife outwards lest the internal carotid artery be endangered. The hemorrhage that follows this operation is usually very trifling, but I have known it to be sufficiently abun- dant to endanger the patient's life. In such cases ice and gallic acid will usually arrest the bleeding. In one case to which I was called I found a gargle of spirits of turpentine suspended in mucilage effectual after all other means had failed. 720 DISEASES OF THE THROAT. DISEASES OF THE PHARYNX. Inflammation of the pharynx of a diffuse erysipeloid character, with low fever, not unfrequently occurs; it is best treated by tbe application of a strong solu- tion of nitrate of silver, the use of emollient gargles, and the internal adminis- tration of ammonia, with bark, stimulants, and support. If it have a tendency to run into sloughing action, the internal administration of the mineral acids, with bark and stimulants, the nitrate of silver lotion and chlorinated gargles are useful. Sometimes abscess forms in the substance of the velum, and then requires to be opened with the knife that is delineated at page 346. Abscess occasionally forms in the cellular tissue behind the pharynx, the pos- terior wall of which is consequently pushed forwards so as to occlude the poste- rior nares, giving rise to a peculiar nasal intonation of voice; it also may inter- fere with breathing by pressing upon the upper part of the larynx. This kind of abscess is often connected with disease of the bones at the base of the skull, or of the upper cervical vertebrae. In many cases, if left to itself, it would burst through the mucous membrane into the mouth, but in others it comes for- wards under the sterno-mastoid muscles into the forepart of the neck. By ex- ploring the pharynx with the finger, which may readily be done, tension and fluctuation through its posterior wall may easily be made out. In these cases, the treatment simply consists in letting out the matter by puncturing the tense membrane covering it. This may be done by means of a sharp-pointed bistoury properly protected, or the ordinary abscess knife. The pus let out is usually offensive, even though the bones be not affected. Tumors are occasionally met with in the post-pharyngeal cellular tissue, giving rise to the same swelling, difficulty in respiration, and deglutition, and lateral projection, as occurs in abscess of this region. These growths are mostly can- cerous, and speedily prove fatal. Polypi in the pharynx usually come down from the nasal cavities, but sometimes spring from the inside of this canal on one or other of its margins. They are usually, when truly pharyngeal, of a malignant character, and grow with great rapidity. The uses of the part are necessarily interfered with, and death may eventually result from obstruction to deglutition and respiration. Cancer of the pharynx of an epithelial character has occasionally been met with. This form of the disease, which is of rare occurrence, does not differ from similar growths elsewhere. DISEASES OF THE 03 S O P H A G U S . All diseases of this mucous canal have a tendency to occlude its passage, and hence are commonly described as strictures of it. In some instances the con- striction of the oesophagus may be of a purely nervous or spasmodic character; but in the majority of instances it is the result either of fibrous or cancerous degeneration of the walls of the canal, or of the projection of malignant growths into its interior. The spasmodic stricture usually occurs in hysterical women, and not unfre- quently results from local irritation occurring after the removal of a fish-bone or some such body from the canal. It is often chiefly seated in the constrictors of the pharynx. In it the symptoms are usually intermittent, the patient expe- riencing difficulty in swallowing certain articles of food, or at particular periods of the day, whilst at other times deglutition is perfect. In many instances it appears simply to be a variety of the hysterical globus. In the treatment of this affection, the patient must be put upon an anti-hysterical plan, with cold douches and electricity to the neck, and the occasional introduction of the bougie to blunt the sensibility of the part. Organic stricture of the oesophagus usually occurs either at the commence- INFLAMMATION OF THE LARYNX. 721 ment or end of the canal, most frequently at the former, opposite the cricoid car- tilage. The patient first complains of difficulty in deglutition, he finds that a portion of the food that he has apparently swallowed, returns into his mouth after a time, and that he is obliged at last to confine himself to slops. On ex- amining the oesophagus by means of a bougie, the surgeon will find a part that appears to be constricted, and at which the point of the instrument is either arrested altogether or passes with difficulty. After a time the patient gradually becomes cachectic, and a painful and distressing death will at last occur from low starvation, or from the irritation occasioned by the formation of abscess around the seat of disease. In the treatment of organic stricture of the oesophagus, care should be taken that the patient is principally kept upon nutritious slops, or upon meat that has been well chopped up, as larger fragments are apt to become impacted at the seat of constriction. Means should at the same time be taken to dilate the stricture. If it be of a fibrous character, such a plan of treatment will be of use ; if cancerous, it is useless to attempt its dilatation, and upon the whole, I think it better not to irritate the disease by pushing instruments through it. In intro- ducing bougies into the strictured part of the oesophagus, there is often a good deal of difficulty in getting the point of the instrument into the narrowed por- tion of the canal. This is more particularly the case when the constriction com- mences suddenly; the oesophagus, as is frequently the case, being dilated into a pouch-like sac above it, in which the food is apt to lodge and the end of the instrument to be arrested, and at the bottom of which a narrow orifice exists, leading into the lower portion of the canal. In these cases much patience and care may be required in overcoming the difficulty. In a patient who had a strictured oesophagus of this kind, who had not swallowed food for nine days, and who was consequently nearly exhausted by starvation, I succeeded, after much difficulty, in getting a No. 5 gum elastic catheter into the stricture, through which nutriment was injected into the stomach. In this case much benefit was afterwards derived by gradually dilating the stricture, which was done on the same principle that has been introduced by Mr. Wakley in the treatment of urethral strictures, — by getting a narrow instrument through the constriction, and then slipping a larger one over it. I first introduced a long narrow bougie through the stricture as a guide, and then slid a gum-elastic tube, well rounded at the end over this; and although the patient eventually died of cancerous degeneration of the oesophagus, with abscess, he was by these means kept alive for many months, enabled to swallow food, and put in a state of com- parative comfort. It is needless to observe that, in the treatment of stricture of the oesophagus by bougies, no force should be employed, lest by any accident the walls of the canal be perforated, or the constriction be dependent on the pressure of a tumor or of an intra-thoracic aneurism. Indeed, it is well, in all cases of difficulty of deglutition dependent on lesion of the oesophagus, that the thorax should be examined, with a view of ascertaining whether such disease may exist, before any treatment by dilatation is undertaken. In cases in which the stricture has become impermeable, the patient must necessarily speedily sink, exhausted by starvation. Sedillot seems to think, that, under such circum- stances, it would be justifiable to lay open the stomach, with the view of intro- ducing food directly into that organ. This plan, however, appears to be some- what too heroic to be adopted in practice. The consequence of such an opera- tion would probably be to save the patient the horror of a lingering death from starvation, by more speedily terminating his existence. DISEASES OF THE LARYNX. Inflammation of the larynx principally occurs in adults, from exposure to cold, to the infection of erysipelas, or to the general occasioning causes of the low 46 722 DISEASES OF THE THROAT. forms of inflammation; it differs essentially from the croup of children, which is attended by an albuminous exudation, and spreads downwards into the bron- chi; whilst in laryngitis, there is no effusion of plastic matter, and the disease is confined to the larynx itself. Laryngitis may not only be of an acute or chronic kind, but it likewise presents two distinct varieties, according to the parts affected, the cause from which it arises, and the condition of constitution in which it occurs; in one, the true acute laryngitis, the inflammation is chiefly seated in the mucous membrane and cartilages; in the other, the cedematous laryngitis, the affection chiefly occurs in the submucous cellular tissue, within and around the larynx. In all inflammatory affections of the larynx, whether acute or chronic, there is great danger to life; the rima glottidis, that narrow chink through which all the air destined for respiration must enter, becomes readily occluded, and asphyxia consequently results. This may happen either by the swelling of the lips of the glottis, from the effusion of plastic matter within or upon them, or by the occurrence of spasm in the larynx; indeed, there is always more or less spasm conjoined with all the inflammatory affections of this part of the air-tube, and this spasm being superadded to already existing mechanical occlusion, com- monly proves fatal. These laryngeal spasms do not at first recur oftener than at intervals of half an hour or an hour, but as the disease advances they become more frequent, and in any one of them the patient may be carried off. It is of importance to bear in mind that death may occur in these cases, although a con- siderable portion of the cavity of the larynx continue free. Thus Dr. Cheyne states that there is always in croup at least three-eighths of the cavity of the larynx open for the transmission of air, and that death must consequently result from some other cause than mere mechanical obstruction. This freedom from permanent occlusion commonly occurs in cases of laryngitis, and the immediate cause of death in the majority of instances appears to be spasm, conjoined with defective arterialization of the blood, which becoming dark and poisonous, causes congestion of the lungs or brain, and thus low pneumonia and con- vulsions. In acute laryngitis the symptoms are those of local inflammatory action of an acute kind, conjoined with those indicative of interference with.the proper admission of air to the lungs. The cartilages and the mucous membrane are the parts principally inflamed, and but little effusion takes place under the mucous membrane; hence the symptoms are not always indicative of such early or intense interference with respiration, as is met with in the cedematous form of the disease. In acute laryngitis there is pain and tenderness on pressing upon the larynx, more especially about the pomum adami. The voice at first is harsh and rough, then stridulous or sonorous, with difficulty in deglutition. The difficulty in swallowing is often at first the most prominent symptom, and continues throughout; dyspnoea, often of a spasmodic character, then comes on, the lips becoming livid, the features pale, and bedewed with perspiration, the eyes watery and bloodshot, and the respiratory muscles being called into violent action, the nostrils are dilated, gasping efforts at breathing, and sudden fits of increased difficulty in inspiring come on; at the same time the pulse becomes feeble, though it continues rapid, and unless efficiently relieved, the patient will speedily sink. When it proves fatal, the acute usually runs into the cede- matous form of laryngitis. The treatment in this disease should be actively antiphlogistic. No time must be lost, otherwise the patient will fall into a hopeless state of asphyxia. Free blood-letting, the application of an abundant supply of leeches to the larynx, and the administration of calomel in large doses, with antimonials, must be had recourse to. If notwithstanding the administration of these remedies, the difficulty in respiration continue to increase, the windpipe must be opened before the lungs and brain become irretrievably engorged. It is no easy matter (EDEMATOUS LARYNGITIS. 723 to determine when it is no longer prudent to trust to active antiphlogistic treat- ment, and when operation should he had recourse to; indeed the determination of this point may be considered as one of the nicest questions in surgery. As a general rule it may be stated, that if notwithstanding the antiphlogistic means above indicated, the dyspnoea get gradually more urgent, and paroxysms of spasmodic difficulty of breathing become more frequent and severe, then no time should be lost in the performance of the operation, for however short a period the disease may have existed. I can truly say that I have seen several cases lost by delaying the performance of this operation, but never one by opening the windpipe too early. Indeed if the opening be even made somewhat early, I do not think that much, if any, harm results, as the larynx is thereby set at rest; and on the laryngitis being subdued by the continuance of proper treat- ment, the aperture which simply served as a breathing-hole may be allowed to close by granulation. In cedematous laryngitis, the disease is seated chiefly, if not entirely, in the submucous cellular tissue, and frequently comes on in the course of chronic affections of the larynx. It may, however, be of a distinctly erysipelatous cha- racter, occurring as the result of exposure to infection, or to atmospheric vicis- situdes. In fact, in many cases it appears to be at times epidemic, and in its pathological conditions resembles closely phlegmonous erysipelas of the part; the mucous membrane becoming red, pulpy, and swollen, and the cellular tissue lying beneath it infiltrated with semi-puriform plastic matter. In this form of the disease, the fauces are reddened, dusky, and swollen; there is much and early dyspnoea, the voice becomes hoarse, rough, and speedily extinct, with much difficulty in deglutition, and on passing the finger over the back of the tongue, the epiglottis will be felt rigid and turgid. There may be some degree of ten- derness about the larynx, but the local symptoms, which are less acute, are attended by a greater amount of dyspnoea than in the active form of laryngitis. In cedematous laryngitis there is also a good deal of spasm associated with the local turgescence. These spasms sometimes come on early, and carry off the patient at once, and are very apt to be brought on by speaking or swallowing; but as the disease advances, more continuous dyspnoea may supervene, with great restlessness, a quick, small pulse, and convulsive breathing, the counte- nance being pale, sunk, and clammy, and the eye dull. Stupor at length super- venes, which speedily terminates in death. The cedematous infiltration in this form of laryngitis is principally confined to the submucous cellular tissue around the epiglottis, at the margins of the glottis, and to that which lies at the back of the thyroid ggi cartilage. In these situations the tissue is distended with sero-plastic fluid, of an opalescent character, so as almost completely to occlude the rima glottidis (fig. 291). It is a pathological fact of much importance that this effusion never extends below the true vocal cords; being limited at this point by the direct adhesion of the mucous membrane to the subjacent fibrous tissue, without the intervention of any cellular membrane. It is of great importance to make the diagnosis between the two forms of laryngitis. In the acute variety of the disease, antiphlogistic treatment is of great moment; in the cedematous form it is comparatively useless, for here effusion sets in early, and nothing is left for the surgeon but to open the air-passages, so as to give the patient breathing-room, whilst the disease is being subdued. In making the diag- nosis, the epidemic character of the affection, the absence of much pain in the larynx, and the dusky-red and swollen fauces point to the cedematous variety. Then also the effect f^. of antiphlogistic treatment should be taken into account. If, after its active 724 DISEASES OF THE THROAT. employment, no alleviation of the symptoms occurs, it is only reasonable to suppose that the obstruction to breathing is owing rather to a purely mechanical obstacle than to simple inflammation. ... The treatment of oedematous laryngitis must be antiphlogistic, though the constitution will not usually bear any very active measures of this description. Leeching under the jaws and over the larynx, the administration of antimonials and salines, will be especially serviceable. In many cases, scarification with a hernia knife or probe-pointed bistoury about the root of the epiglottis, the sides of the olottis, and the back of the thyroid cartilage, will be found the most ready means of unloading the infiltrated mucous membrane. In these cases it is, however, especially necessary to open the windpipe before it is too late, and the luncrs become engorged. After the proper employment of the means that have been indicated and their failure, the less delay there is in opening the air- passap-es through the crico-thyroid membrane the better. The surgeon should not wait until extreme and continuous dyspnoea has set in; this may never occur, the difficulty in breathing being rather of a spasmodic than continuous character, and in one of these spasms life may suddenly become extinct. The lungs also may become fatally congested if the difficulty in breathing be allowed to con- tinue too long. The operation adds but little to the patient's danger, but the increased risk is immense if it be delayed to an advanced period. Not unfre- quently this operation is delayed until too late; there is, I think, more risk of doing this than of opening the windpipe too early. When once dyspnoea with laryngeal spasm has fairly set in, every moment is precious, and the patient may at any time be carried off by the recurrence of the spasmodic seizures. The patient does not die gradually asphyxiated, but is suddenly seized with a spasm that terminates his existence. If the oedematous laryngitis become chronic, sloughing and putrid suppu- ration of the submucous cellular tissue may occur, as in phlegmonous erysipelas of other parts of the body, and the patient may die partly from asphyxia and partly from typhoid symptoms, with putridity of the breath and mouth. In these cases the administration of stimulants and tonics, more particularly port wine and bark, with free sponging of the part with a strong solution of nitrate of silver, will be urgently required. The larynx is liable to various chronic diseases of a serious character, some of which are incurable, leaving a permanent impairment of voice, or alteration in the use of the larynx. These affections present great variety, and as many of them are attended by loss of voice, they are included under the general term of aphonia. In many cases this affection results simply from cold in relaxed and debilitated subjects, or after long exercise of the voice in persons not accustomed to public speaking. This affection commonly occurs amongst clergymen, and hence is familiarly known as the clergyman's sore throat; it is also of frequent occurrence amongst singers, but may be met with among all classes of the community. Aphonia commonly appears to depend upon chronic inflammation of the mucous membrane of the rima glottidis, but is more espe- cially dependent on disease of that extensive mucous surface which stretches from the base of the epiglottis over the back of the thyroid cartilage. In many instances it may also extend into the interior of the larynx, and at last may implicate the vocal cords. In all these situations the membrane is red- dened and inflamed, ulcerated at points, and secreting a thin and acrid mucus. In other instances again, the disease implicates the soft palate, the back of the nares, and the neighboring parts; and in these cases the morbidly inflamed surfaces will be seen to secrete a thick puriform fluid, which usually hangs in a broad streak down one side of the posterior wall of the pharynx. The symptoms of this chronic irritation of the mucous membrane in these situations consist of habitual tickling or spasmodic cough, a veiled or hoarse character of voice, with perhaps, at last, complete extinction of it, so that it TREATMENT OF CHRONIC LARYNGITIS. 725 cannot be raised above a whisper; at the same time there is usually a feeling as if there was some constant cause of irritation in the throat, attended by a desire to cough up and expectorate. As the disease advances, the expectoration becomes more and more puriform, the cough increases, the patient emaciates, is affected with night-sweats, and at last sinks from what is called laryngeal phthisis. When the posterior nares and the neighboring parts of the pharynx are affected, the symptoms are not so severe, though they may eventually be- come so by the extension of the disease downwards. These affections are very frequently mistaken for chronic bronchitic, or catarrhal attacks. From the first they may be distinguished by the absence of all auscultatory signs in the chest, and examination of the pharynx will prevent the disease being confounded with an ordinary catarrh. This examination, however, requires to be properly done, so that a full view may be gained of all the parts engaged in the morbid action. This is best obtained by seating the patient opposite a good light, and then, depressing the root of the tongue at the same time that it is drawn forwards by means of a proper tongue-depressor or spatula, directing the patient to inspire. In order to examine the mucous mem- brane at the back of the pharynx, and in the neighborhood of the posterior nares, the velum may be raised by any convenient instrument. The treatment of these various chronic inflammations of the mucous mem- brane of the pharynx and larynx requires to be conducted by the topical appli- cation of a solution of the nitrate of silver, which may almost be looked upon as specific in these diseases. The practice of treating chronic disease of the larynx by the application of a strong solution of the nitrate of silver is by no means of recent origin. Many years ago it was employed by Sir C. Bell, and before him M. Bretonneau applied the solution in these cases by means of a sponge attached to a piece of whale- bone. Of late years this practice has been brought very prominently before the profession by Trosseau, and by the American surgeons, especially by Horace Green and J. Warren. Of the great value of this treatment in laryngeal disease there can be no doubt. I believe it to be almost impossible to bring deeply-seated and very chronic inflammatory or ulcerative affections of this part of the air-passages to a satisfactory termination by any other means. The mode of application that is the simplest and most effectual, consists in depressing the tongue with a proper spatula, and then passing a throat-sponge, consisting of a small piece of this material firmly attached to a curved whalebone stick, and saturated with a solu- Fig. 292. --------------------------------_= tion of nitrate of silver, down to the parts that are diseased, so that the liquid may be applied to the whole of the affected surfaces. This solution should vary in strength from half a drachm to a drachm of the salt to an ounce of distilled water; most commonly, the latter strength will be most useful. This plan of treatment has been much practised of late years in this country, and with con- siderable success in a large number of cases. Some of its advocates, however, not content with curing in this way disease that is visibly seated in the throat, state that the morbid action extends down the trachea into the bronchi, and that it is necessary to follow it in these situations. They accordingly speak of pass- ing the proband between and beyond the vocal cords, and of sponging and mopping out the interior of the larynx and the lower parts of the air-tube, and of applying the caustic solution to them, as if this were a proceeding that could 726 DISEASES OF THE THROAT. be adopted with as little difficulty as passing the sponge into the nares. I can- not believe, however, that this practice, though commonly spoken about and professedly employed, is ever in reality carried out. Any one acquainted with the physiology of the larynx knows how acutely sensitive it is, and how it resists the introduction of any foreign body by the most violently spasmodic fits of coughing, in its normal state; and any surgeon who has seen the effects resulting from the fair and complete inhalation of a drop or two of the solution of the nitrate of silver in a morbid and irritable condition of this tube, must feel sure that no sponge saturated with a solution of this caustic could ever have been thrust down beyond and between the vocal cords. On inquiring into the evidence on which is founded the doctrine of the passage of the sponge probang through and beyond the vocal cords, I have failed to discover that any of a positive character exists, and so far as I can gather from the writings of its supporters, it would appear that the reasons from which it is inferred to do so may be arranged under the following heads: — 1st. The sensations of the patient. 2d. The sensations of the surgeon. 3d. The analogy offered by the introduction of tubes for the purposes of artificial respiration, and by the inhalation of foreign bodies. These different conditions we must, examine somewhat in detail. 1st. The sensations of the patient. — The exquisite degree of sensibility pos- sessed by the larynx need not be dwelt upon here. Mr. Porter in his admirable work " On the Surgical Pathology of the Larynx and Trachea," very justly says, " It (the larynx) is placed as an outwork to protect the important organ of respiration, and rejects vehemently and with spasmodic violence, every sub- stance that can by possibility prove offensive or injurious." Many years ago Magendie shows that this was the most sensitive part of the respiratory tube; and in the year 1843 I published in the " Medical Gazette" a series of experi- ments, which demonstrated the same fact. Since then I have had repeated opportunities of verifying the correctness of these observations in the human subject in cases of cut-throat and aerial fistula, in which, by means of probes introduced through the artificial opening, I have tested the extreme sensibility of the larynx as compared with other parts of the air-passages, and have often observed the spasmodic irritation and great distress suffered by the patient when its mucous membrane is touched from within, and this, even though the part is no longer subservient to the purposes of respiration, and the sensation of asphyxia not experienced, which" would otherwise be induced, and which would greatly aggravate the distress. If a long, bent probe, or a gum-elastic catheter, be passed over the back of the tongue, two classes of sensations will be elicited, according to the part that is touched. If the instrument be directed down the pharynx, and altogether behind the larynx, into the oesophagus, as in the introduction of the stomach- pump tube, the patient will experience some little distress, which is easily quieted. The face will become slightly congested, and the eyes, perhaps, some- what suffused, with a disposition to cough, a slight feeling of choking, and some constriction about the chest. All these sensations, however, are transitory. These symptoms may be termed pharyngeal. If, on the other hand, the probe or tube be bent forwards, so as to touch the lips of the glottis, and more particularly if an attempt be made to push it on into the larynx, then a widely different train of symptoms will be induced. The patient suffers extreme distress and anxiety; there is great sensation of constriction about the chest and throat, spasmodic difficulty in breathing, and an inability to speak; the countenance becomes much congested and livid, the eyes protrude and stream with tears, he stands up", gropes wildly with his hands, and is pacified with great difficulty. As the attack goes off, there are deep, TREATMENT OF CHRONIC LARYNGITIS. 727 sobbing inspirations, and catches in the breathing. These symptoms, which are analogous to those induced by the irritation of the inside of the larynx through an aerial fistula, may be termed laryngeal. The first class of symptoms is produced by the application of an irritant to the mucous membrane of the pharynx; the second, to irritation of the larynx. Their severity will, in a great measure, depend upon the nature of the irritant applied. They will necessarily be far more severe when a sponge soaked in a caustic solution is thrust down the throat, than when a smooth and unirritating gum elastic tube is passed. Both these classes of symptoms are commonly met with after the application of the throat probang. When the pharyngeal symptoms occur, there can be little doubt that no sponge saturated with a strong solution of nitrate of silver has penetrated into the glottis. But is not the case different when the laryngeal symptoms are fully developed ? Must these not, when existing in their full intensity, be taken as evidence of the introduction of the sponge probang through the glottis ? To this I have no hesitation in answering in the negative. I have repeatedly brought on these symptoms, in the most marked degree, without the use of a sponge at all, or the introduction of any solid body into the larynx. In fact, if a drop of a strong solution of the nitrate of silver is fairly inspired into the larynx, the most intense distress, and appearance of impending asphyxia will be induced. I saw this well exemplified some time since at the hospital, whilst applying a strong solution of nitrate of silver by means of lint wrapped round a probe to a syphilitic ulcer on the soft palate, altogether away from the larynx; a drop was accidentally inhaled, when the patient was sud- denly seized with one of the most intense attacks of laryngeal spasm that I have ever seen; for a few moments she appeared to be about to die asphyxiated, and had all the laryngeal symptoms above described fully marked. In many cases I am in the habit of applying the solution of the nitrate of silver by means of a strong glass tube bent nearly at right angles about an inch from one extremity. A few drops of the solution are introduced into the bent end of the tube, and this being passed over the back of the patient's tongue, so as to overhang the glottis, the other end is closed by the pressure of the finger. The patient having previously emptied his chest, is then told to take a deep breath, and, at the moment of doing this, the finger being removed from the tube, the solution contained at its bent end is inhaled fairly into the larynx; and, when so applied, will produce the symptoms already described. Thus, then, we may conclude, that when the pharyngeal symptoms exist alone, the sponge cannot have passed into the true air-passages; and that the laryngeal symptoms, however intense they may be, afford no evidence of more than the inhalation of a drop or two of the caustic solution into the glottis. 2d. Sensations of the Surgeon. — The little reliance that can be placed on the mere sense of touch in many explorations of the mucous canals is well known to surgeons. It often happens, for instance, that in the attempt to relieve retention of urine from enlarged prostate, the catheter is supposed to be lodged in the bladder, when it has only reached the dilated sinus of the urethra: so also in passing bougies up the rectum, that the instrument has entered the sigmoid flexure, when, in reality, it has curled back upon itself. Those practitioners, however, who believe in the possibility of passing the sponge probang beyond the vocal cords, rely much on the sensations communi- cated by its passage through this narrowed portion of the larynx. They say that in passing the instrument to the proper depth, a certain sense of obstruction is felt; against this, which is believed to be the vocal cords, the_ sponge is firmly pressed for a moment, when the obstacle yields, and the instrument passes onwards into the air-tubes. On the withdrawal of the probang, the same feeling of constriction is experienced by the sponge being drawn up against the cords. These sensations are undoubtedly experienced. I have many times 728 DISEASES OF THE THROAT. felt them myself, and, had I judged by them alone, could have been almost certain that I had passed the instrument between and below the vocal cords, and this belief would have been strengthened by the circumstance that in many of the instances in which this constriction was felt the laryngeal symptoms were manifested. I soon found, however, that this was by no means uniformly the case, but that it not unfrequently happened that the pharyngeal symptoms only were induced; and that consequently, in accordance with what I believed to be the proper state of sensibility of the larynx, the interior of that tube could not have been traversed by the caustic sponge. Finding also the same sensation often experienced in the introduction of bougies and tubes into the oesophagus and stomach, it was clear that it could have nothing to do with their progress through the larynx; and I was led to conclude that it was occasioned by the passage of the instrument through that narrowed portion of the end of' the pharynx, or the beginning of the oesophagus, where the cartilages of the larynx, projecting backwards, give rise to a certain amount of constriction, compressing the gullet, as it were, against the spine. Here the instrument meets with a certain degree of obstruction, which is partly mechanical and partly occasioned by spasm of constrictors of the pharynx, and, on this being overcome, passes on with a sudden slip, again to meet with a degree of constriction on being withdrawn. In numerous experiments on the dead body that I have made on this point, I have very frequently found that the instrument had passed into the oesophagus, when, from the sensation it gave, those who had introduced it felt confident that it had entered the air-passages. In fact, the shape of the sponge probang, as it is always sold (fig. 292), is such that it cannot be made to enter the larynx, and to pass beyond the vocal cords in the dead body, without the employment of a considerable degree of force, and by means of those manipulations which are alone admissible in the living patient. A probang, with a short curve, such as those that are uniformly employed, has a natural tendency to take the direct passage, as it were, down the oesophagus, instead of turning forwards to enter the larynx. When the curve is much increased, as in an ordinary catheter, the sponge may, during life, be passed between the lips of the glottis, but it cannot even then be made to pass between and below the vocal cords, in con- sequence of the curve being too large to be admitted into the diameter of the trachea. The evidence of the New York Academy Commission fully warrants this statement; for the reporters remark, that notwithstanding the most perse- vering efforts with the whalebone slightly bent, as used by Dr. Green, and with patients who quietly submitted to the test of experiment, the results were entirely negative. In no instance did it enter the trachea. In two instances, with the whalebone curved like a common catheter, the sponge was thought to have entered the larynx, but with repeated attempts it could not be forced between the vocal cords, and the suffocation was so great that it was necessary to withdraw the instrument. The fallacy of the sensations of the surgeon is well illustrated in the following extract from the report of the Commission of the New York Academy: — " We witnessed in cases 11 and 21 the fallacy of Dr. Green's opinion as to the success of his experiment, though based on so large an experience. In both instances, whilst positive that he had successfully passed the instrument (an elastic tube) into the trachea, the patient vomited through the tube, and thus demonstrated his error." From these observations, then, I would conclude that the sensations of the surgeon afford no reliable evidence as to the course taken by the instrument. 3d. In asserting that the sponge probang can be passed into the air-passages, much reliance has been placed on the analogy afforded by the introduction of tubes for the purpose of artificial respiration, and in the occasional inhalation of foreign bodies. Does any such analogy really exist? I think not. It TREATMENT OF CHRONIC LARYNGITIS. 729 seems to me that so very different a degree of irritation would be set up by the introduction of a smooth, well-oiled tube of small calibre, through which the patient can breathe, and from which consequently there is no risk of suffocation, and the passage of a caustic sponge, which not only would stimulate the part violently, but would necessarily induce temporary asphyxia by blocking up mechanically the air-passage, that no analogy can be drawn from the one case to the other. To do so, seems about as reasonable as to infer, that because a gum-elastic or silver catheter may be passed along the urethra, therefore a whalebone rod, tipped with a sponge soaked in a caustic liquid, might also be introduced into the bladder. With regard to the introduction of foreign bodies into the larynx, it appears to me that there is no analogy whatever between this accident and the passage of the caustic sponge. In the one case, the parts' are taken by surprise, the foreign body being accidentally sucked into the chest by a rush of air, during inspiration, through an open glottis. In the other case, the patient is prepared for what is about to take place, involuntarily and instinctively resists, and, hold- ing his breath, keeps the glottis closed. But setting aside this question of analogy, which is of little moment, is the introduction of tubes, even into the larynx so very easy and simple and certain a procedure as some writers seem to suppose it to be ? On the dead body, undoubtedly nothing is easier than to pass a catheter into the larynx, and down into either bronchus; but is it so in the living? That excellent surgeon, Mr. Porter, of Dublin, when speaking of the introduction of Desault's tubes through the rima glottidis, in cases of cut-throat, says : "Awkward and reiterated attempts produce inconceivable distress, and even when performed with the utmost dexterity, it must unavoidably excite cough and restlessness." And again : " Every time the instrument touches the larynx, the patient becomes anxious and restless; he tosses himself about, and coughs convulsively; and each motion, whilst it increases his own distress, renders the performance of the operation more difficult.....Can such a patient endure the irritation that a few mo- ments' unsuccessful poking at the rima glottidis will inevitably occasion ?" The truth of these remarks must be acquiesced in by every surgeon who has ever attempted the operation there described. On this point, the evidence of the New York Academy Commission is pecu- liarly valuable. That Commission, in its inquiry, employed two tubes, the size of a No. 10 catheter: one, selected by Dr. Green, was slightly bent at its ex- tremity, and was one of the kind employed by him in his practice. The other consisted of a catheter with a wire stilette, bent with a curve, the segment of a circle six inches in diameter. This tube does not appear to be used in practice, but was employed for the purpose of comparison. The result of the experiments with these tubes was, that Dr. Green (who was the only one that employed it) failed in passing the tube with the small curve in thirty-five out of thirty-eight trials, or in about ninety-two per cent, of the cases; and that the tube with the large curve was passed in eight cases out of thirteen; whilst the sponge pro- bang failed in every case (eighteen) in which it was tried. "From these experiments it would appear that the instrument best adapted to succeed in cathetcrism of the air-passages is the tube having a large curve; whilst the least adapted to enter the trachea is the sponge probang. In the course of these experiments a point of much interest was elicited by the Commission, —viz., that a patient might blow out a lighted candle or col- lapse and inflate a bladder attached to its free extremity, through the tube even though it had never entered the trachea, but had been purposely passed into the oesonhasus. , . ,, i • ,i . On this third point, then, I think we are warranted in the conclusion that there is not sufficient analogy between the introduction of the sponge probang and that of a catheter tube into the larynx, to lead us to suppose the passage of 730 DISEASES OF THE THROAT. the former instrument possible, because that of the latter is occasionally prac- ticable ; and that the introduction even of a tube of the same shape as the sponge probang is an operation of extreme difficulty, failing in far the greater proportion of cases in which it has been attempted; and that the introduction of foreign bodies into the larynx is effected under totally different conditions to that in which the sponge is attempted to be passed. Finally, I think that we are fully justified in adopting the conclusion of the Commission of the New York Academy, that there is no reliable evidence that the sponge probang has ever been passed through and beyond the vocal cords. The inhalation of the nitrate of silver in powder is most conveniently done by mixing it, in proper proportions, with some innocuous, impalpable powder, such as ground and dried sugar. The strength may vary from one part of the nitrate of silver to twelve, sixteen, or twenty of the sugar. A small quantity of the powder so prepared should be put into the end of a thick glass tube, which has been bent nearly at right angles, about one inch from its extremity. The surgeon, placing his finger over the orifice of the straight part of the tube, carries the bent end behind the tongue, over the epiglottis; he then directs the patient to make a sudden inspiration, and at the moment of his doing so takes away his thumb, so as to allow the powder to be drawn out of the tube and into the air-passages along with the current of inspired air. In this way the nitrate of silver may, in some cases, be very conveniently applied to the whole of the affected mucous surfaces without the irritation produced by the friction of the sponge. The injection of the solution of the nitrate of silver may easily be done by means of the instrument that is here delineated (fig. 293), and which I have had constructed for this purpose. It consists of a silver tube, perforated at the Fig. 293. end, and having a small piston moving in it with a sponge attached to its lower surface. The instrument is charged by dipping the end in the solution, and then drawing back the piston-rod. It is then passed into the pharynx, or be- tween the lips of the glottis, and the fluid injected into the air-passages or upon the inflamed surfaces in a number of fine streams, by pushing down the piston and compressing the sponge. By means of this laryngeal syringe the nitrate of silver can be applied to any part of the pharynx, without irritating the tender mucous membrane by the contact of a rough body, and by applying its nozzle to or between the lips of the glottis, the fluid may be readily thrown down into the interior of the larynx with the greatest certainty and ease. In those cases in which it is wished to apply the solution of the nitrate of silver into the air- passages, I far prefer using this simple instrument to the ordinary sponge, the mere pressure of which upon a tender mucous surface may be a source of irrita- tion. When the mucous membrane behind the velum, or of the posterior nares is affected, the solution may readily be injected against these parts by turning the end of the instrument upwards, and then injecting it directly on to the affected surfaces. In whatever way the caustic is used, its application should be repeated about every second or third day, in order to insure its full effects In some instances, however, advantages may be obtained by using it every day; in others, again, a longer interval is required than that just stated. In the more advanced forms of chronic disease of the larynx, the mucous membrane becomes infiltrated with plastic deposits, which also form upon its surface in the shape of vegetations, and at last run into ulceration, with much SPASMODIC CROUP. 731 narrowing of the rima and muco-puriform discharge. These diseases are often of a syphilitic origin, and after continuing for some length of time give rise to hoarseness, cough, shortness of breath, a pale, pasty and cedematous look about the face, with suffused eyes and constant difficulty in breathing. Under these circumstances there is a constant tendency to acute inflammation supervening on the chronic laryngeal disease, and the affection commonly proves fatal by the induction of oedema glottidis, often coming on with great rapidity. Necrosis of the cartilages of the larynx not unfrequently happens in the more advanced forms of this affection, attended with all-the signs, constitutional and local, of the so-called laryngeal phthisis, and by the expectoration of large quan- tities of fetid puriform sputa, often streaked with blood, and occasionally con- taining masses of the necrosed and disintegrated cartilage. In many cases abscesses form outside the tube, and after much irritation and distress open externally, and not unfrequently they are met with to such an extent as to undermine and disorganize the greater portion of the tissues of the anterior part of the neck. Where they correspond to the necrosed patches of cartilage they give rise to aerial fistula, through which bubbles of air escape during respiration. In the treatment of these more severe diseases of the larynx, the daily appli- cation of nitrate of silver will be found of great benefit. It should be freely applied to, or injected upon the mucous membrane about the epiglottis, within the lips of the glottis, and more especially that loose and filamentous tissue which is extended over the back of the thyroid cartilage, and which is commonly the seat of much chronic irritation, and the chief source of the muco-puriform discharge. At the same time the internal administration of the bichloride of mercury with sarsaparilla will often be found of great service, more particularly in those cases in which the disease is of a syphilitic character; the patient being kept in a regulated temperature, not allowed to exert his voice, and avoid- ing all laborious exertion. Whenever acute inflammation supervenes in these cases, with a tendency to oedema about the glottis, the patient should be nar- rowly watched, as he may readily be carried off by the sudden swelling of the lips of the rima, or the supervention of spasm. In such cases as these, the air- passages may require to be opened to allow of respiration to be carried on, and this operation must not be delayed until such time as the patient falls into an asphyxial condition. Nervous affections of the larynx occur both in children and adults. In children this affection, commonly called spasmodic croup, comes on suddenly and runs its course with great rapidity. The child is seized, often without pre- vious warning, with difficulty in breathing, uses violent efforts to inspire, be- comes black in the face and convulsed, and may die before anything can be done for his relief. In other instances again he gapes and gasps a few times, and eventually recovers himself with a long deep-drawn whooping inspiration. In such cases as these, the treatment at the time of the fits consists in dashing cold water in the face, in exposing the body to a cur- rent of cold air, and in using friction to the extremi- ties. If asphyxia occur, artificial respiration must be kept up either through an opening made in the wind- pipe or by the mouth. In the adult, these spasmodic affections of the larynx may come on either from pure hysteria, or from irritation of the laryngeal nerves by the pressure of tumors or aneurisms upon them. In other instances again they appear to arise from the presence of some local inflammatory mischief about the glottis. In the hysterical form of the affection the ordinary reme- dies for hysteria, together with cold douches, will Fig. 294. be of essential service. 732 DISEASES OF THE THROAT. In some cases, however, the obstruction to respiration is so great, that the sur- geon may almost think it necessary to have recourse to operation. When the disease arises from irritation to the trunks of the nerves, such a procedure is seldom justifiable, as the occasioning cause is usually in itself of a fatal character. Tumors or polypi occasionally form in the larynx. They are commonly gra- nular, or small cauliflower-looking bodies, though they occasionally attain the size of a hazel-nut (fig. 294). They necessarily interfere with respiration, and at last may give rise to asphyxia by obstructing the cavity of the larynx. OPERATIONS ON THE WINDPIPE. The windpipe may require to be opened either to allow of the formation of a temporary breathing aperture, in consequence of the obstruction of the larynx from causes that are speedily removable; or, the air-passages may require to have a permanent aperture established in them in those forms of chronic laryn- geal disease, in which the obstruction depends upon such organic alterations of structure as are not remediable. Amongst the conditions that require the tem- porary opening of these passages may be mentioned, all acute inflammatory affections of the larynx, together with the various nervous or spasmodic diseases of this organ; so also certain traumatic conditions may require this operation, as the impaction of masses of food in the gullet inducing asphyxia and not admitting of immediate removal, the presence of foreign bodies in the air-pas- sages, and oedema of the glottis from wounds of the thyro-hyoid membrane. The establishment of a permanent aperture in the air-passages is especially required in chronic diseases of the larynx, attended by thickening of the mucous membrane, abscess, or necrosis of the cartilages, and in fact such conditions as do not admit of removal; so also in polypi of the larynx a permanent opening below the obstructed point may be required. It is a question whether the windpipe should be opened in cases of croup. Were croup merely a disease of the larynx it would doubtless be proper to per- form the operation; but it has been incontestably shown that in this affection when it is severe, the inflammation is not confined to the larynx, but usually extends down the bronchi even to the lungs, which become engorged and affected, so that death very commonly results from this cause, as much or more than from the laryngeal disease. Hence opening the trachea alone will not suffice in saving life in the majority of instances, as the child will ultimately die of broncho-pneumonia. In this respect, the result of tracheotomy in croup differs remarkably from that of the same operation for acute laryngitis in the adult. A serious objection also to the performance of this operation in croup is the difficulty attending it; the struggles and screams of the child, by in- ■creasing the tendency to spasm, interfere materially with the surgeon's attempt to open the windpipe. Indeed I have known more than one case in which the bleeding was so profuse as to prove fatal. But although, as a general rule, I fully agree with Porter in strongly reprobating this practice in croup, yet cases are doubtless occasionally met with, in which the disease is so clearly limited to the larynx—the respiration being free throughout the lungs and bronchi—that the surgeon may feel himself justified in endeavoring to save the little patient, struggling against overpowering asphyxia, by opening his windpipe. In several such cases,.to which I have been called by other practitioners, and which were apparently most favorable to the operation, I have considered myself justified in doing this, though in no instance have I as yet succeeded in eventually saving a child by this operation; and I think that the general experience of surgeons in this country is unfavorable to its performance. Trousseau, who strongly advocates tracheotomy in croup, has, however, published a large number of successful cases in favor of this proceeding. But even in Paris it is not a very successful procedure; thus it appears that at the Hospital for Sick Children in OPERATIONS ON THE WINDPIPE. 733 that city, the operation has been performed 215 times in the last five years, and that of these only 47 were cured. Unless we assume that the disease, as occur- ring in Paris, is different from the form of croup we meet with here, I think it may fairly be doubted whether an operation could be necessary in many of these instances, and whether a large proportion of the children might not have reco- vered under ordinary medical treatment. When it has been determined to open the windpipe for acute disease, more especially supervening on chronic laryngitis, the less delay there is in having recourse to operation the better, as the patient may at any moment be seized with laryngeal spasm, and be carried off. The operation ought always, however, to be completed, even though the patient has apparently expired before the windpipe has been opened, for resuscitation may, even in these extreme cases, be effected by artificial respiration. When life hangs on so slender a thread as it does in urgent cases of laryngeal obstruction, the first touch of the knife may cause a spasmodic seizure that may give rise to apparent death. It has twice happened to me to operate under such circumstances, and in both cases to be fortunate enough to save the patient's life. In one case to which I was called about five years ago by my friend Mr. E. Baker, the patient, an elderly woman, was apparently dying from the supervention of acute upon chronic laryngeal disease. I lost no time in making an incision into the crico-thyroid membrane, but at the first touch of the knife she sunk back apparently dead. I immedi- ately completed the operation, and introduced a large silver tube, through which the lungs were inflated, when, in the course of a few minutes, the action of the heart recommenced, and the patient eventually recovered. She has never, however, been able to breathe without the silver tube, which she wears in her windpipe up to the present time. In another case to which I was hastily sum- moned by my friend Mr. Tweed, I found the patient, a young woman, in the last stage of asphyxia from acute disease of the larynx. I immediately pro- ceeded to operate, with the assistance of my then house-surgeon, Mr. Lister. As the patient's neck was short and thick, and the veins excessively turgid, there was profuse hemorrhage on the first incisions being made; whilst waiting a minute or two until this would cease before opening the windpipe, the patient fell back and apparently expired. I lost no time in plunging the scalpel into the crico-thyroid membrane, and cutting down through the cricoid cartilage, so as to make a free aperture into the air-passages. On endeavoring to set up artificial respiration, 1 found the chest clogged with inspissated mucus, which prevented the entrance of air into the lungs; the life of a fellow-creature being at stake, and dependent on the immediate and full establishment of arti- ficial respiration, I felt there was only one thing to be done, and that was to empty the chest of the matters that loaded it, and that this must be done instantaneously. I accordingly applied my lips to the wound and sucked out three or more mouthfuls of blood and mucus, when I had the satisfaction to see that air could be got to enter the lungs. By keeping up artificial respiration for some time, the heart began feebly to act, the face to become less livid, and the circulation to be re-established; the patient eventually did well, and is now alive and in good health. In opening the windpipe, the surgeon has the choice of two situations, in which he may make the aperture, — either in the crico-thyroid membrane by laryngotomy, or in some part of the trachea by tracheotomy. _ Besides these two established operations, some surgeons have performed a, third, — laryngo- tracheotomy, by opening the membrane and dividing the cricoid cartilage with the upper rings of the trachea. Whichever operation is performed, so soon as the windpipe is opened, the patient is seized with an attack of spasm and convulsive cough, often attended by much struggling and distress, during which the whistling occasioned by the passage of the air through the new passage is very loud and marked. The 734 DISEASES OF THE THROAT. patient, however, soon reoovers himself, and then breathes naturally and easily the signs of asphyxia disappearing. Laryngotomy is an easy operation, the crico-thyroid membrane is almost superficial, and may readily be reached by making a vertical incision in the mesial line, between the sterno-thyroid muscles, about an inch in length, and then a cross cut through the membrane with an ordinary scalpel. The air- passage having thus been opened, a silver tube, curved on the flat, may be readily introduced and retained by tapes round the neck. The only trouble- some result that can occur in this operation is the wound of a small arterial branch, the inferior laryngeal, that crosses the membrane. I have never seen any trouble arise from this, but should it occur the hemorrhage would readily be arrested by pressure or ligature. Tracheotomy consists in making an opening into some part of the trachea, by exposing the tube and cutting across one or more of its rings. In performing tracheotomy the patient's shoulders should be supported with pillows, and his head be thrown as much back as practicable. An incision about an inch and a half in length should then be made with a scalpel directly in the mesial line from the cricoid cartilage downwards. After dividing the integuments, any veins that present themselves should be avoided as carefully as possible, being held aside with a blunt hook. By using the point of the scalpel to a limited extent, and dilating the deeper portions of the incision with its handle or with a director, the trachea may be reached with safety; it must then be opened by pushing the point of the knife, with its back turned towards the sternum, between two of the rings, and cutting upwards, through about three of them (fig. 295). The tube must then be introduced and retained by tapes round the neck. This operation is often attended by extreme difficulty, and not unfrequently with a considerable amount of danger. The difficulty in exposing the tube increases greatly as the incisions approach the sternum, and are far greater in stout short-necked persons than in those of a different development. There are three situations in which the trachea may be opened, either above, underneath, or below the isthmus of the thyroid body, which usually crosses the air-tube opposite its third or fourth ring. Above the isthmus, the trachea is comparatively superficial, and is not covered by any venous plexus, nor does any other source of difficulty present itself to the surgeon. Where the isthmus crosses the trachea, this tube is overlaid by a venous plexus as well as by the glandular structure. Below the thyroid gland, the air-tube is overlapped by the sterno-hyoid and sterno-thyroid muscles and by the inferior thyroid veins, which are of large size, together with some tracheal branches from the inferior thyroid artery; and not unfrequently an irregular arterial branch ascends in this situa- tion in front of the trachea to supply the thyroid body. The carotid arteries also are in close relation to the vessel on either side, and opposite the episternal notch it is crossed by the left carotid and by the innominata, which vessel has been seen by Mr. Macilwain to cross the tube at the very point where tracheo- tomy is usually performed. A glance at these important relations will suffice to indicate the difficulty that must, in many cases, occur in exposing and open- ing the trachea. This difficulty is greatly increased when the veins of the neck have become turgid in consequence of the pulmonic obstruction. It will also be seen that the trachea is less covered, and may consequently be much more readily reached above, than below the isthmus of the thyroid gland; and though some surgeons, as Velpeau for instance, have recommended the opening to be made in the lower part of the tube, the greater number advise that it should be entered in its upper part, though the incision may, if necessary, be carried down- wards as low as, or even through the isthmus. The difficulties occurring in tracheotomy are chiefly referable to three causes; DIFFICULTIES IN TRACHEOTOMY. 735 1st, the risk of profuse hemorrhage; 2d, the difficulty in opening the air-pas- sage ; and 3d, trouble in introducing the trachea-tube. 1st. The hemorrhage in this operation may occur either from arteries, veins, or the thyroid gland. Arterial hemorrhage is less frequent and troublesome than the bleeding from other sources. When it occurs it chiefly happens from the wound of some anomalous branch, or from that of the small tracheal vessels. Desault has however mentioned a fatal case in which death arose from a wound of the carotid. The arterial anastomosis of the isthmus of the thyroid body may, if this part be enlarged, occasion some difficuly in the performance of the operation, but the main source of danger unquestionably proceeds from the venous bleeding. Not only are the plexuses of veins of large size, more particu- larly where they cover the lower part of the trachea, but as has already been observed they become immensely gorged by the asphyxia that necessitates the operation. Hence, when wounded, the bleeding may be so abundant as scarcely to be controllable, and may retard very greatly the after-steps of the operation. Many surgeons of authority in these matters, advise that the windpipe should not be opened so long as the bleeding is abundant, lest the blood entering the bronchi and lungs through the aperture, asphyxiate the patient. I think, how- ever, that in many cases the best way to arrest this hemorrhage is by opening the trachea, and thus enabling respiration to go on, for as the lungs unload themselves the bleeding will cease. 2d. Another difficulty in tracheotomy sometimes consists in opening the tube after it is exposed. In consequence of the convulsive breathing of the patient, the sterno-mastoids are put upon the stretch, thus increasing considerably the depth of the wound in the neck, and at each short and gasping respiration, the air-tube is rapidly pumped or jerked to and fro, approaching to and receding from the surface in such a way that the scalpel cannot be thrust into it with safety. In order to do this with the least risk, a sharp pointed hook should be passed between two of the rings, and the tube being thus fixed, opened by cut- ting upwards (fig. 295). Or the hook being grooved along its convexity, as Fig. 295. Chassaignac recommends, is to be introduced under the cricoid cartilage, the air- tube pulled up and opened by sliding the scalpel along the groove of this hook- Fig. 296. director I have found it advantageous in some cases to open the trachea with a cutting-hook, such as is here represented (fig. 296). By means of an instru- 736 DISEASES OF THE THROAT. ment of this kind, the trachea is first fixed and then divided without danger to the patient. The danger from hemorrhage, and the difficulty in opening the trachea, are much greater in children than in adults. Before the age of puberty, this tube is deeply seated, covered with a quantity of Fig. 297. loose granular fat, containing many veins, and is of small size, so that a slight deviation of the incision to one side or the other may readily lead the sur- geon astray, and into dangerous proximity with the carotid artery. 3d. After the trachea has been opened, the next point is to introduce, in cases requiring it, a proper tube. In the first instance, one of a conical shape should be employed, as it is not only introduced more readily than a cylindrical one, but fills up completely the aperture in the trachea, so as to prevent the draining of blood into the lungs. In passing the tube, some little difficulty may occa- sionally be experienced, owing to the elasticity of the sides of the incision in the windpipe, in conse- quence of which one of them is apt to get doubled under the end of the instrument. This may he avoided by the use of Dr. Fuller's bivalve tube introduced closed, and then expanded by slipping a canula into it; or one side of the cut in the trachea may be held aside with the forceps or a blunt hook, whilst the tube is slipt under the other. If the rings of the trachea are very rigid and unyielding, the silver tube may most conveniently be introduced by expanding the incision by means of the trachea-forceps (fig. 297), and then passing the tube between or under their blades. My friend and colleague, Mr. H. Thompson, has recommended a very simple and most ingenious mode of opening the trachea, by which the dangers and difficulties of the old operation, such as have just been described, are in a great measure avoided. This operation consists in making the puncture at once into the windpipe by means of the tracheotome as here depicted (fig. 298), which Fig. 298. serves at the same time as a guide to the tube into the opening. By means of this instrument a puncture is made transversely through the skin and cellular tissue, and between the first and second rings of the trachea, so that the carti- lages are not injured. When the blades have been introduced they should be held there by the left hand, and the screw in the handle gradually turned, so that the separation of the blades may dilate the contiguous structures until the aperture is sufficiently large to allow a tube to be introduced. Mr. Thompson states that the proper point for introducing the instrument may always be determined by feeling for the projection of the cricoid cartilage, and defining its lower border clearly with the finger. The point of the instru- ment should then be introduced transversely in the mesial line a quarter of an inch below this cartilage, when it will enter the space between the first and second rings. The screw is then to be turned, the blades expanded, and the tube introduced, as above described. This operation is certainly one of the DIFFICULTIES IN TRACHEOTOMY. 737 safest, easiest, and most speedy modes of opening the trachea, and appears to be a very great improvement upon the ordinary methods of performing trache- otomy. It is not, however, applicable to children, nor would it, I think, be desirable to have recourse to it in those cases in which the trachea requires to be opened for the extraction of foreign bodies from the windpipe, as the vertical incision tends to facilitate their escape. On comparing tracheotomy as ordinarily performed, with laryngotomy, I think there can be little doubt that the surgeon should give the preference, in all cases where it is practicable, to the latter operation, on account of its greater simplicity, safety, and rapidity, though in these respects it appears to be equalled by the method introduced by Mr. Thompson. In all those cases in which the obstruction to respiration is dependent upon inflammatory effusions into the sub- mucous cellular tissue, whether it be dependent upon idiopathic or erysipelatous laryngitis, or upon the irritation and inflammation excited by swallowing boiling water or the stronger acids, the swelling, for reasons that have already been mentioned, never extends below the true vocal cords; hence an opening into the crico-thyroid membrane will always be below the seat of obstruction. An objection it is true has been urged to laryngotomy in these cases, that it does not allow of the patient wearing a tube without much irritation being induced. This, however, I have not found to be the case in my practice. I have at pre- sent two patients under observation, in both of whom I introduced a silver tube in this situation a considerable time back, and in whom no special irritation has been occasioned by it. In one case the tube has been worn for eight, and in the other for nearly five years; the larynx in both instances having been nearly completely occluded by chronic disease. When the windpipe requires to be opened for the extraction of a foreign body, tracheotomy should be performed in preference to laryngotomy, as the latter operation does not admit of sufficient space for its expulsion or extraction. In children, tracheotomy is almost always a tedious and often a dangerous operation, the exposure of the trachea requiring very careful dissection, and much time being often lost before it can be punctured, owing to the free hemor- rhage which usually occurs. In my opinion, laryngotomy is the operation that should, as a general rule, be preferred, and this opinion is based on the following reasons: — 1st. That as in laryngotomy the air-tube is always opened below the seat of obstruction, there can be no necessity to make an aperture further from the seat of disease. In laryngitis, whether that affection assume the acute or chronic character, the obstruction in breathing is in a great measure mechanical, and dependent upon the infiltration of the submucous cellular tissue of the larynx, and partly of the large plane of this tissue, which lies behind the box of the larynx, and which, by expanding, as it were, into the pharynx, obstructs deglu- tition, and afterwards, by the extension of this swelling and infiltration to the lips of the glottis and the interior of the larynx, causing an impediment to the entrance of air into the bronchi. But, as has been pointed out by Mr. Prescott Hewett, this submucous cellular tissue terminates at the true vocal cords, where the mucous membrane becomes directly applied to the subjacent fibrous struc- tures, the swelling and consequent mechanical impediment is confined to the limits of the thyroid cartilage, and any opening made below this will clear the lowest limit of the disease, which is always accurately and almost mathematically bounded below by the vocal cords. Hence an aperture in the crico-thyroid membrane is quite as effectual as one in the trachea. 2d. Laryngotomy is a far safer operation than tracheotomy. On this point I need scarcely dwell; a glance at the anatomy of the parts concerned will be sufficient to establish it. The crico-thyroid membrane is nearly subcutaneous, and no parts of importance can be wounded in opening it, if we except the small inferior laryngeal artery, which crosses it, and which might be cut across, 47 738 DISEASES OF THE THROAT. but from which I have never seen any trouble arise. The trachea, on the con- trary, is not only deeply seated, but covered by a large plexus of blood-vessels, which, when rendered turgid by the asphyxiated condition that exists when these operations are required, pours out a large quantity of dark blood, and thus seriously embarrasses and delays the surgeon at a time when the life of the patient depends on the speedy admission of air to his lungs. 3d. Laryngotomy can be much more quickly performed than tracheotomy. This I look upon as an inestimable advantage in many of the cases requiring operation; a few seconds, more or less, being sufficient to turn the balance either in favor of life or of death. The rapidity with which laryngeal obstruction — partly mechanical and partly from spasm — sets in, is sometimes so great, more particularly when an acute inflammation supervenes on chronic disease of the larynx, that life may be extinguished before the surgeon has time to open the windpipe, if he endeavors to do so by tracheotomy. In extreme cases, such as where the lungs have become slowly engorged, the action of the heart is already enfeebled, and a sudden spasm occurring at the glottis, will at once place the patient beyond recovery. But even though life appears for the moment extinct, it is the imperative duty of the surgeon to open the air-passages as speedily as possible, and to endeavor, by means of artificial respiration, to recall the flicker- ing spark; and it is impossible to experience a greater satisfaction in the exer- cise of our profession, or to witness a greater triumph of art, than in thus snatching a patient out of the very jaws of death. It is a practice with some surgeons not to open the windpipe until all, or nearly all, the bleeding has ceased. But in this way much valuable time may be consumed, and the patient may be fatally exhausted by a tedious and pro- longed operation, and by the loss of an unnecessarily large quantity of blood. The hemorrhage in these operations is almost entirely of a venous character, and is, in a great measure, dependent on the distension of the veins of the neck that occurs in asphyxia, as the result of the accumulation of blood in the right cavities of the heart, consequent upon the obstructed circulation through the lungs; and the bleeding will continue so long as that obstruction remains unre- moved. But as the respiratory process is re-established, this obstruction to the pulmonic circulation diminishes, the cardiac cavities become unloaded, the venous turgescence of the neck subsides, and the hemorrhage proportionately lessens. This I have repeatedly found in asphyxia artificially induced in ani- mals, and have more than once seen in the human subject in cases in which it has become necessary to open the windpipe at once, without waiting to arrest hemorrhage. Hence, except in those instances in which an arterial twig or large venous trunk has been wounded, and which must, of course, be secured, the occurrence of bleeding, though tolerably smart, need not deter the surgeon from opening the windpipe; as the relief afforded to respiration will induce a corresponding and rapid dimunition in the venous turgescence of the neck, and in the consequent flow of blood from the wound. Trachea-tubes should be of such a calibre throughout as to admit of respira- tion being carried on through them without any effort on the part of the patient. Many of those that are to be met with in the instrument-makers' shops, though very wide at the mouth, are far too narrow and contracted at the lower aperture to allow a free and unimpeded passage for the air of respiration, being made very conical in order to admit of easy introduction, and to occlude completely the opening in the windpipe, so as to prevent the entry of any blood by the side of the tube. The disadvantage attending this mode of construction may in a great degree be remedied, by having a longitudinal opening like the large eye of a catheter cut in the side of the tube, immediately above the inferior aperture. One great difficulty that the surgeon has to meet in cases of tracheotomy or laryngotomy is to keep the tube from being clogged and obstructed by mucus. TRACHEOTOMY — TRACHEA-TUBES. 739 It is usually stated that the tube may be kept clear by the occasional introduc- tion of a feather, of a piece of sponge fixed to a stick, or a bit of lint wrapped round a probe. In this way it is true that the frothy or spumous mucus that collects in the tube may be readily enough cleared away; but this simple means will in very many cases be found to be quite ineffectual in removing another kind of mucus that in certain conditions rapidly accumulates to a considerable extent within the tube. On examining a trachea-tube that has been worn for but a few hours, it will be found that its interior becomes gradually lined by a coating of dry, gummy, and very tenacious mucus, which is so firmly adherent to the metal as to render it necessary, before the tube can be properly cleaned, to detach this lining by means of a penknife or pointed probe; or, what is better, by pouring boiling water through the tube. This tenacious mucus, collecting, as it does, in largest quantity at the inferior aperture, and at the curve of the trachea-tube, may block up its calibre to a very great and dangerous extent, whilst the mouth of the tube appears to be perfectly pervious and free, and though feathers and pieces of stick, armed with sponge or lint, have been intro- duced from time to time; but these, passing over this dry mucus, are quite unable to detach it from the side of the tube, and merely bring away the sputa and more frothy mucus. Mr. Obre has devised a very simple means to remedy this inconvenience. It consists in the trachea-tube being made of uniform calibre throughout, and having an interior tube accurately fitted to it, and projecting about one-eighth of an inch beyond the lower extremity of the outer tube. It is in the projection of the internal tube beyond the lower end of the external one that the great utility of this contrivance consists. If the two tubes are of the same length, or still more, if the innermost tube be the shorter, a plug of mucus may be left at the end of the outer canula, on the withdrawal of the inner tube. But if this be the longer of the two, the end of the outer tube will be effectually cleared every time it is withdrawn, which may be done as often as any mucus collects, without in the slightest degree disturbing the patient. The two tubes are Fig. 299. Fig. 300. Fig. 301. fixed by means of a button, attached to the edge of the outer one (figs. 299, 300). I have found it convenient to have the ordinary set of three trachea- tubes made in this way, the internal tube being the largest, the middle the next in length, and the external the shortest. By this arrangement the smaller trachea-tube is made to serve the purpose of the internal canula. When used for laryngotomy, these may conveniently be curved on the flat (fig. 301), their longest diameter being lateral instead of antero-posterior, thus adapting themselves to the form of the aperture in the crico-thyroid membrane. 740 DISEASES OF THE THROAT. DISEASES OF THE PAROTID. Parotitis or mumps is a common affection, especially in children, though it not unfrequently occurs in adults. It usually arises from cold and wet, and is frequently infectious. Both sides of the neck are usually affected, and the swelling, stiffness, and pain are often considerable, though it very rarely happens that suppuration occurs unless it be in the lymphatic glands of the neighbor- hood. Metastasis, though of rare occurrence, has been described as occasionally happening to the testicle or breast. The treatment for this affection is of a simple character, the application of hot fomentations and leeches if it be severe; the administration of saline purgatives, and, as the affection is on the decline, frictions with camphorated oil will hasten its resolution. Tumors of the parotid itself are not so frequent as morbid growths situated upon or in the vicinity of this gland, yet occasionally they occur either upon it, or consist in an actual transformation of its structure. The tumors usually met with here are of a fibrous nature and often encysted; they are hard, deeply attached, but yet movable on careful manipulation; round, and often attain a very great size, up to that of, a cocoa-nut even (fig. 302); the skin covering them is thin but not adherent, and not unfre- quently a net-work of veins covers the mass. These growths frequently send prolongations under the lower jaw, and then occupy the whole of the space between its angle and the mastoid pro- cess; when firmly bound down, they involve the blood-vessels and nerves in this important region, coming into rela- tion with the styloid process and its muscles, and even pressing upon the pharynx. In consequence of the large size that these tumors may attain they have a tendency to produce atrophy of the parotid, and often by interfering with the cerebral circulation occasion various congestive symptoms about the brain. In some cases the parotid may undergo cancerous infiltration, the tumor then presenting the characters and running the course of the ordinary forms of malignant disease. It is of importance to effect the diagnosis in their early stages between the non-malignant and the malignant varieties of this affection. In the fibrous tumor there is always mobility, and although the attachment may be deep, the skin is not involved, and the outline of the mass is usually well defined, square, and somewhat lobulated. In the scirrhous growth there is no mobility, but the mass is solidly fixed, its outline is ill-defined, the skin soon assumes a reddish- purple color, brawny, and presents the usual characters indicative of subjacent malignant action. When these tumors are medullary, they grow with consider- able rapidity, feel soft, pulpy, and are ill-defined in their outline, especially under the ear and by the ramus of the jaw. In the treatment of these tumors, extirpation is necessarily the only course that can be adopted; and this should not be attempted if the disease be malig- nant in its characters; for as it would be impossible to get away its deeper attachments, the growth to a certainty would easily return. Even if the disease be of a simple character, care must be taken that every lobule and prolongation be extirpated, for if any is left, however small, it will, without doubt, become TUMORS OF THE NECK. 741 the nucleus of a new tumor. In removing tumors in this situation, the super- ficial incisions should be made free, and either longitudinal or crucial, so that the whole mass may be fairly exposed. The edge of the knife must then be directed against it, and the dissection carried on from below upwards, so that one division of the blood-vessels supplying it may be sufficient. After the tumor has been well loosened by the division of investing fasciae and structures, and it is surprising how movable it often becomes after this has been done, though it may previously appear to have been incorporated solidly with the subjacent tissues, it should be taken hold of by the hand or a large double hook, and drawn well forwards whilst the deep dissection is being carried on. In prosecuting this, the surgeon must particularly guard against wounding the external carotid artery and the portio dura nerve, which are especially exposed to injury. In some cases the division of these structures cannot be prevented, as they are incorporated in the mass that is undergoing removal. The hemor- rhage under these circumstances would of course be abundant, but may imme- diately be arrested by the ligature of the divided artery; indeed, in most cases the bleeding is profuse, owing to the unavoidable section of nutrient vessels and of large subcutaneous veins, but may generally be readily arrested by ligature and pressure. In other instances, however, by keeping the edge of the knife carefully against the tumor and by drawing it well forward, so as to loosen it in its cellular bed at each stroke of the scalpel, removal of the morbid mass may be effected without the division of any important vessel or nerve. After the extirpation of some small tumors of a fibrous or encysted character lodged in the substance of the parotid, there is often a great tendency to copious secondary hemorrhage, requiring pressure, or even the application of the actual cautery for its arrest. Excision of the parotid itself is occasionally spoken of, but is Very rarely if ever done. I believe that in most, if not all, the cases in which it is stated that complete removal of this gland has been accomplished, tumors overlaying and compressing it, have been mistaken for it. It is evident that a diseased parotid could not be removed without the division of the external carotid and the portio dura. Tumors of the neck. Besides tumors in the parotid region, fatty, fibrous, and encysted growths are not unfrequently met with in the submaxillary space, and in the posterior triangles of the neck. In these situations they may occa- sionally attain a considerable size, though they seldom extend very deeply, being superficial to the deep fascia. Hence when the integuments and superfi- cial structures covering them are divided, the growth may be insulated with sufficient facility, its fixity being in a great measure due to its being bound down by the investing fascia rather than to its having contracted deep adhesions. Before determining upon the removal of a tumor situated in one of the triangles of the neck, it is necessary that a diagnosis be effected of its nature, and that some opinion be formed of the probable extent of its deep attachments. The first point to ascertain is, whether it be simple or malignant. If simple, it will usually have been many years in growing; it will be hard but not stony, lobulated or somewhat square-shaped; the patient's general health being good. It will generally be found to be movable, though not perhaps to any great extent, and will present no sign of incorporation with neighboring structures; the fibres of the platysma will not appear to spread over it, and the sterno- mastoid may be traced to one side of or below it. Under such circumstances the removal of the tumor may be undertaken by any surgeon possessing a fair share of anatomical knowledge and manual skill, with every prospect^ of success. But if the tumor be of stony hardness, have implicated the skin, be immovable, the whole head moved on any attempt at drawing it aside; if it be defined under the jaw and ear, or rapidly growing, soft and pulpy to the feel, deeply seated under the angle of the jaw, evidently below the platysma and deep fascia of the neck, and possibly beneath the sterno-mastoid, then no attempt at 742 NATURE AND TREATMENT OF BRONCHOCELE. extirpation should be undertaken, as the mass could either not be removed with safety, or if it were by any possibility extirpated, then necessary contami- nation of the neighboring parts would certainly lead to a speedy recurrence of the disease. A peculiar cystic tumor, the hydrocele of the neck, has been described by Maunoir and Phillips. The disease usually appears in the posterior inferior triangle, forms a largish bladder-like tumor, unilocular in some cases, multilocu- lar in others; filled with a yellow or chocolate-colored sero-albuminous fluid, and may attain so large a size as to interfere with deglutition and respiration; the skin covering these growths is not discolored, but thin and expanded. The treat- ment consists in the introduction of a seton after the tumor has been tapped. Enlargement of the lymphatic glands of the neck either terminating in chronic induration or abscess, is of such common occurrence as to constitute perhaps the most frequent form of glandular enlargement. The tumors thus formed, present nothing peculiar in their progress or treatment when occurring in this situation, except that when abscess forms it should be opened early by a small incision, and in such a direction, corresponding to the natural folds of the skin, as to leave as little scarring as possible. BRONCHOCELE. The thyroid gland is subject to various chronic enlargements which commonly go by the name of bronchocele. It may be simply hypertrophied, and may then attain a very considerable size; in some cases forming an immense lobulated tumor on the forepart of the neck, such as is met with in various districts of this country and of the continent, in which the disease is endemic. In the majority of instances these tumors are, however, of but very moderate size, commencing at first as a mere fulness and uniform or rounded enlargement of the isthmus, or of one of the lateral lobes of the thyroid gland, and gradually increasing, until perhaps by the pressure of the growth confined between the sterno-mastoid muscle and the deep structures of the neck, respiration and deglutition become seriously affected. There is a remarkable connection between tumors of the thyroid gland of this kind, and a general anemic condition of the system. In London nothing is more common than to find a certain degree of bronchocele in pale and bloodless women and girls; indeed so frequent is the coincidence that it is impossible not to regard it in the light of cause and effect. Mr. W. Cooper has pointed out the fact, that great prominence of the eyeballs is frequently associated with these conditions. In some cases cystic tumors are met with in this gland, either associated with general hypertrophy of it, or occurring independently of this. These cysts, which may be single or numerous, usually contain a dark bloody-looking fluid, and have often cauliflower-like excrescences projecting into their interior. In some instances pulsation has been observed in a bronchocele. This may either be communicated by the artery lying beneath it, or be owing to the very vascular character of the tumor itself. In either case, when confined to one lobe only, care must be taken not to confound the beatings with carotid aneurism, a mis- take that I have known to occur, and the diagnosis of which has been adverted to at page 539. The treatment of bronchocele must vary according to the size and character of the tumor; when small, and associated with anemia, and of comparatively recent formation, it is best treated by improving the general condition of the patient by the administration of iron internally, especially the iodide, with the external application of the iodine or iodide of lead ointment. When of large size, its absorption cannot, I think, be expected to take place by these or any other means, and the question then arises as to the propriety of having recourse to operative interference. The excision of the tumor is seldom to be thought of; DISEASES OF THE BREAST. 743 its vascularity is so great, and the arterial supply that it receives from both sets of thyroid arteries so abundant, that any attempt at extirpation must generally be attended by such profuse hemorrhage as necessarily to prevent the completion of the operation. Cases have, it is true, occurred to Roux and others, in which laro-e bronchoceles have been successfully extirpated; but these operations must be looked upon as altogether the exception in the treatment of the disease; and cases are certainly not often met with in which a surgeon would think it proper to undertake so serious a procedure for an affection that is not necessarily mortal. In the event of its being thought desirable to operate, the better plan would be, after exposing the tumor, to enucleate it as much as possible with the handle of the scalpel, ligaturing carefully all the vessels divided as they were cut. The ligature of the thyroid arteries has been practised by some surgeons, and it is stated, with a certain degree of success. The difficulties and danger of the operation, the uncertainty of its results, and the readiness with which the arterial supply would be forwarded to the tumor from other sources, have caused it to be but little resorted to by surgeons of the present day. The introduction of a seton across the tumor is occasionally attended by beneficial results. This operation, however, is not unaccompanied by danger; a patient on whom it was being performed in the neighborhood of London a few years ago, having lost his life by the puncture of a vein at the root of the neck, into which air was spontaneously admitted. In some instances the employment of pressure has been of use, especially in conjunction with the iodine inunctions; though it is not easy to apply this means, and any considerable degree of it can necessarily not be_ borne, on account of the increased difficulty of respiration that is thus occasioned. In fact, the compression exercised upon the tumor by the sterno-mastoid muscle in some of these cases is occasionally so considerable, that it becomes necessary to divide its tendon subcutaneously, in order to relieve the trachea from the constriction to which it is thus subjected. When the tumor is chiefly of a cystic character, the fluid contents may be drawn off by tapping, and an endeavor may be made to get the cysts to close by inducing inflammation in them by the injection of tincture of iodine. CHAPTER LII. DISEASES OF THE BREAST. These affections when occurring in the female, are of great interest to the surgeon, not only on account of their great variety, but from the difficulty of diagnosis attending them and the importance of determining the question of operative interference in connection with them. The mammary gland is subject to certain anomalies as to development; thus, in some instances, it has been found to be altogether wanting. Sir A. Cooper and Froriep both relate instances in which this structure was not developed, and in which the ovaries were also deficient. A more remarkable anomaly con- sists in the development of a number of supernumerary breasts Birkett has collected 14 reported cases, in which there were more than two breasts; more frequently there is but one supernumerary gland, sometimes two and occasion- ally though very rarely, three have been met with, constituting quintuple 744 DISEASES OF THE BREAST. mammae. Supernumerary nipples have likewise been found to occur; two to each breast have been met with, each communicating with the gland, and passing milk. Most frequently the supernumerary breast is situated somewhere in the neighborhood of the normal gland, as on the anterior part of the thorax; and where four are developed they have been found placed in two parallel rows one above the other. Occasionally they have been met with in very strange situa- tions ; thus they have been seen on the outer part of the thigh, in the groin and on the back ; and children have even been known to have been suckled by these abnormal breasts. Diseases of the breast seldom occur before puberty, being most frequently met with either during lactation, when the functions of the gland are in a high degree of development, or towards the termination of menstrual life, when the actions of the organ are necessarily influenced by the changes that are taking place in the uterine system. Before puberty, the breast occasionally, but rarely, becomes the seat of inflammation and abscess, in all probability acci- dentally so, these changes taking place in it in the same way that they might in any other part of the body. More serious disease has, however, been met with in the mammary gland, even at this very early age; thus, Mr. Lyford has recorded a case of cancer of the breast in a girl of eight. As the period of puberty approaches, the breasts often swell, become hard, knotty, and somewhat painful, indicative of some commencing change in the generative system. In other cases again a precocious hypertrophy may take place, frequently attended with severe neuralgia in the part. When puberty occurs the breasts naturally enlarge, and often become tender, and occasionally one undergoes a certain degree of hypertrophy, increasing greatly in bulk beyond the other. These various changes, though exciting alarm in females, cannot be regarded as of any serious importance, and seldom require more than the simplest surgical treatment. Neuralgia of the breast occasionally occurs to so severe a degree as to con- stitute a positive disease, either in girls or at a more advanced period of life, when it not unfrequently complicates other more serious affections of this organ. It is especially apt to occur in young, delicate, unmarried females of the hyste- rical temperament, though it is often met with in strong, ruddy-looking women, who are perhaps subject to neuralgic pains in the back, and in other situations. Most commonly the catamenia will be found to be irregular, and uterine con- gestion, inflammation, or ulceration, will be discovered on examination; indeed, of late, since the attention of the profession has been drawn to these affections, I have scarcely ever failed to detect one or other of these conditions in the uterus in cases of irritable breast. In neuralgia of the breast the mammary gland may be of its normal size and consistence, but in some instances the whole of it is more or less indurated and hypertrophied. There is always much general pain and aching deeply in its substance, with cutaneous tenderness of its surface, and lancinating or radiating sensations that extend into the axilla and down the arm. These painful sensa- tions are commonly increased before the menstrual period, and not unfrequently alternate in opposite breasts. The diagnosis of this affection from the more serious mammary disease may usually be effected by attending to the superficial and radiating character of the pain, to the temperament of the woman in whom it occurs, its shifting seat, and the absence of any positive signs of disease in the breast. The treatment consists especially in attention to the condition of the uterine organs; unless this be done in a proper way, the disease will prove to be ex- cessively rebellious and troublesome to manage. By using the speculum, how- ever, when necessary, and removing any uterine irritation that may be found by proper remedies, this affection will yield with far greater readiness than by any other plan of treatment. At the same time, anti-hysterical constitutional HYPERTROPHY OF THE BREAST. 745 Fig. 303. remedies may be employed; the preparations of iron administered, when neces- sary ; and the local pain relieved by the application of belladonna and opiate plasters, or inunctions with atrophine ointment. Simple hypertrophy of the breast not unfrequently occurs, associated with very severe neuralgia of the organ. An increase of size, such as naturally takes place during pregnancy, between the fourth and the ninth months, will occasionally commence at puberty, and go on until the organ attains an enor- mous bulk, as in fig. 303, which represents the breast of a girl of fifteen. In some cases the breast has been found to weigh as much as twenty pounds after death; and after removal, a breast of this kind, taken from a young woman under thirty, has weighed no less than twelve pounds, being entirely composed of its normal tissues, greatly hypertrophied. In these cases of hypertrophy, both breasts are usually affected, though one is com- monly more so than the other. When first this morbid condition commences, the breast preserves its usual shape, though it is increased in bulk; but as it enlarges it gradually projects forwards, drawing down the skin of the shoulders, of the sides of the chest, and even of the back, and hanging downwards, until, as in a case mentioned by Berard, it has been known to reach to the knees. The treat- ment of this affection is very unsatis- factory. The general health must be attended to, and an endeavor may be made to excite lactation, and thus to un- load the vessels of the breast by the em- ployment of galactogogue remedies. I do not think that amputation of the organ should be performed in these cases, unless the growth attain so great a size as to render life a burden. The lobular hyper- trophy of the breast, described by Sir A. Cooper, as occurring chiefly in unmarried women between thirty and forty years of age, and which appears on manipula- tion to be composed of several solid but movable masses, that after a time begin to diminish in size, until the breast at last atrophies, and is in a great measure absorbed, seems to me to be rather a species of the chronic mammary tumor than of pure hypertrophy. The lacteal secretion is occasionally the cause of abnormal conditions in the breast; thus the milk may appear at unusual times, a twelvemonth, tor instance, after weaning; it has occasionally been known to be secreted in chil- dren, and in some remarkable instances in men. In other instances, again, after parturition, there is a total absence of milk, either owing to want of development in the gland, or to debility on the part of the mother, I he oppo- site condition will occasionally occur, and an excessive flow of milk may con- tinue in hysterical females after the child has been weaned. In such cases as these, the galactorrhea may be checked by the employment of tonics, the administration of acids, &c. ___ It may happen during lactation that one of the lactiferous ducts becomes obstructed, either by its becoming obliterated by inflammation or occluded by 746 DISEASES OF THE BREAST. the deposit in it of a small concretion — a lacteal calculus. In either case the walls of the duct may be expanded, so that at last it constitutes a moderate- sized cyst, fluctuating on pressure, and evidently containing fluid. In some cases the lacteal tumor has been known to attain an enormous size. A M. Walpy has related a case in which he drew off ten pounds of milk by tapping a collection of this kind. These tumors may exist for a considerable time. Dupuytren records an instance in which it had existed for ten months, and Cooper one of a year's duration. In these chronic cases the milk usually under- goes changes; becoming creamy, thick, and oily, and in some instances would appear by the absorption of its watery parts to leave a solid residue. In other instances, again, the milk appears as if diffused through the substance of the glands and its ducts, constituting a spongy semi-fluctuating tumor. Velpeau has pointed out that these lacteal deposits undergo a series of changes, somewhat similar to those that take place in blood that has been extravasated, becoming absorbed in whole or part in some instances, in others left fluid, and in others becoming encysted. In these cases the readiest mode of getting rid of the tumor is, as Sir A. Cooper advises, to make an oblique puncture from the nipple towards it, by means of a trochar and canula, so that a fistulous track may be left, along which the milk is discharged, and thus got rid of, the child being at the same time weaned, so that the secretion may cease. In some cases after weaning, the milk may be diffused into the substance of the gland or collected into masses of curd, forming hard nodules, which give a good deal of trouble, and may eventually go on to ^ome of the forms of inflammation that will imme- diately be described; these swellings are usually best got rid of by frictions with somewhat stimulating embrocations, such as camphorated oil, &c, by which their absorption is promoted. Infiammation of the breast may take place at any period of life, but is usually associated with that change in the function of the gland which occurs during lactation. It is commonly met with during the first month or two after the birth of the child, and seldom occurs during weaning. The inflammation may affect any one of the constituents of which the breast is composed, and may be limited to this; thus it may take place in the nipple—in the subcutaneous cel- lular tissue lying between the skin and the gland—in the gland itself, or in that extensive plane of cellular membrane upon which the gland rests, and which intervenes between it and the pectoral muscle. But although the inflammation commonly affects these different parts, yet in many cases the whole of the breast appears to be affected, and no distinct implication of any special tissue can be made out. Infiammation of the nipple and areola usually occurs at an early period of lactation in delicate women, and especially during their first pregnancy. It commences in the follicles of the part, accompanied by superficial ulceration, abrasion, fissure, and cracks, with oozing of a small quantity of thin, sero-puri- form fluid, great pain during suckling, so much so indeed as to prevent the proper continuance of this act; and is usually accompanied by a great deal of constitutional irritation. In some instances the fissured state of the nipple would appear to precede the setting in of inflammation; in other cases again, the inflammation is the primary condition. When the areola and nipple are inflamed, these parts become conical, red, and swollen, with much pain, owing to the density of the subcutaneous tissue in this situation. When this disease, commonly called cracked nipple, has set in, most relief is afforded by the appli- cation of the nitrate of silver to the bottom of the fissures, and over the inflamed surface. This application, though painful at the time, gives the patient after- wards more complete ease than any other with which I am acquainted. In some instances the application of the citrine ointment, and in other and slighter ca^es that of collodion is useful. When inflammation exists, with superficial TREATMENT OF INFLAMMATION OF THE BREAST. 747 abrasion, but without any distinct crack, the employment of astringent applica- tions, such as the tincture of myrrh and of catechu, borax and honey, or spirit and water, may be useful. In these cases also, a leaden nipple shield may be employed with advantage, and the state of the infant's secretions should be carefully attended to; the occurrence of aphthous ulcers in the mouth being followed with especial frequency by the disease in question. Abscess of the areola not unfrequently occurs in suckling women, with the ordinary signs of local inflammation, terminating in circumscribed suppuration. The treatment consists in the application of warm poultices made with lead lotion, and lancing the part early. In doing this, care should be taken that the cut be made from the centre of the nipple towards the circumference of the areola, so as not to cut the lacteal ducts. The infiammation of the breast, which, as it generally terminates in suppura- tion, is usually called milk abscess, may occur in three situations; 1st, in the subcutaneous cellular tissue; 2d, in the bed of cellular tissue in which the mammary gland is lodged; and 3d, in the gland itself. 1st. Inflammation, followed by abscess of the subcutaneous cellular tissue of the breast, though commonly occurring during lactation, is more frequently met with than any other form of inflammation in this region at other periods of life, more particularly about the age of puberty. Its symptoms are those of simple phlegmonous inflammation of these structures, differing in no way from abscesses of this kind in other situations, except that it is always distinctly circumscribed. 2d. When inflammation occurs in the cellular plane which lies between the mamma and the pectoral muscle, it diffuses itself over the whole of the cellular layer, and almost invariably runs into abscess with considerable rapidity, giving rise to great pain in this situation of a deep, heavy, and throbbing character, much increased by moving the arm and shoulder, attended by swelling, oedema, and a slight red blush upon the skin. The breast becomes prominent, is conical and projecting, the whole organ being pushed forwards by the pressure from behind; the subcutaneous veins become engorged, and at last abscess forms. It is not always easy in these cases to determine whether suppuration has_ taken place or not, the depth at which matter forms rendering it impossible in the early stages to detect fluctuation until it approaches the surface; its presence may, however, be suspected by the occurrence of deep-seated throbbing pain, oedema, and some superficial redness. The abscess at last points at some part of the margin of the gland, usually at its lower and outer side, where the matter seems to gravitate; after a time, however, it will commonly appear at other points of the circumference of the gland, beyond which it always extends, though it seldom, if ever, perforates the structure. I have, in more than one instance, seen a series of four or five apertures, forming a large circle round the margin of the gland. It very commonly happens that the aperture through which the pus discharges itself in these situations, degenerates into fistulous canals, by no means easily closed. 3d. Inflammation of the gland itself is not of such frequent occurrence as either of the other forms of abscess; when the whole of the organ is affected, it gives rise to great swelling of the breast, with severe aching and lancinating pain, and much constitutional disturbance, usually of an irritative type. JNot unfrequently one lobule only of the gland becomes inflamed and then the local signs are proportionately limited, and occasionally cease. As Velpeau has pointed out, one lobule after another may become inflamed, so that a succession of abscesses forms in different parts of the gland. As the inflammation advances to suppuration, the skin is reddened, assumes a dusky hue, becomes glazed, has a peculiar greasy appearance, and pits on pressure. When matter has formed, the tension of the superficial parts with oedema and perhaps deep-seated fluctua- tion determine its presence. 748 DISEASES OF THE BREAST. In the treatment of inflammation and abscess of the breast occurring during lactation, it must be borne in mind that we have not a sthenic inflammatory con- dition to deal with, but that the disease almost invariably happens in pale deli- cate women, commonly of a strumous habit, and weakened by recent parturition ; indeed the affection appears to be rather an inflammation of an irritative and congestive, than of a sthenic character. It is therefore obvious that antiphlo- gistic means of an active nature are not admissible; and the best plan of treat- ment appears to consist in keeping up the strength of the patient by proper con- stitutional support, at the same time that the local inflammation is checked by topical antiphlogistic measures. The first thing to be done is to prevent the occurrence of suppuration; if this can be accomplished, which is, however, rarely the case, much will be gained. In order to effect this, the breast should be supported in a sling, so as to lessen congestion in it, and the arm at the same time should be fixed to one side in order to prevent traction of the pectorals and movement of the submammary cellular tissue. If the patient's strength is good, leeches may be applied; in the majority of cases, however, they will not be required, but warm evaporating lead lotions or the assiduous application of chamomile or poppy fomentations may be substituted in their stead ; at the same time the milk should be drawn off by means of a breast-pump or sucker, the child being put to the unaffected breast or weaned, and an occasional saline purgative administered. When suppuration is impending, the application of fomentations may be continued, the patient being allowed a more liberal supply of nourishment, with a moderate quantity of malt liquor; and so soon as matter can be felt, it should be cut down upon and let out by an aperture in the most dependent position. It is of great importance that the matter should be let out early, and by an opening into the lowest part of the abscess; if it is not, it burrows deeply, diffusing itself through the cellular tissue under, beyond, and around the gland, and opening at several points, leaves long fistulous tracks per- forating the breast in various directions. When suppuration is going on, the patient's strength must be supported with tonics, the mineral acids, bark and quinine. Porter must be liberally allowed, and plenty of nourishment given. The sinuses that are left may usually be got to close by attention to the state of the general health: should they not do so, however, the employment of pres- sure and the use of stimulating injections may, in time, accomplish this. In the event of their proving rebellious, it has been proposed to slit them up, but this is an unnecessarily severe practice, and may, I believe, in all cases be dis- pensed with. Chronic or encysted abscess of the breast, is a disease of great importance, inasmuch as it simulates closely various tumors in this situation; so much so, indeed, that it is only with extreme difficulty that the diagnosis is effected in some cases. It may commence either as the result of acute lacteal inflammation, but more commonly without any distinct cause; as the consequence, probably, of a very chronic and gradual engorgement of the cellular tissue in this region. An indurated indolent swelling forms, and this may gradually soften in the centre, but fluctuation may for a long time be very indistinct, and even absent, being obscured by the thick wall of plastic matter that is thrown out around the collection of pus. It is owing to the deposition of this dense mass of limiting fibrine that the encysted abscess is commonly developed as a hard and apparently solid lump. It is in general not very distinctly circumscribed, and of but moderate magnitude, after a time remains stationary, or but slowly increases with but little pain during a space of many months; and is not unfrequently attended with retraction of the nipple. The diagnosis of this form of abscess is of great importance, inasmuch as it has not unfrequently been excised for tumor of the breast. I am acquainted with many instances in which this mistake has been committed. Such an error may, however, commonly be avoided by observing that the abscess commences CHRONIC MAMMARY TUMORS. 749 during lactation; that although it is of slow formation and without pain it is not distinctly circumscribed, but gradually fuses in an irregular manner into the neighboring tissues; that it is not freely movable, but rather incorporated with adjacent parts; and that elasticity, or even fluctuation may be commonly felt at one part of it. Should there be much doubt in the case, the introduction of a grooved needle by giving issue to the pus, will always determine its true nature; indeed this simple means of diagnosis should never be neglected in all cases in which there is reason to suspect the possibility of the apparent tumor of the breast being in reality an abscess. The cure of these encysted abscesses of the breast may most conveniently be effected by making a puncture into them, and then passing a seton across them in a perpendicular direction ; the inflammation thus excited in the tumor will speedily lead to its being softened down, and even- tually disappearing. TUMORS OF THE BREAST. The study of the various tumors of the breast, more especially in a diagnostic point of view, is of the first importance to the practical surgeon; for though it might be supposed that it would be easy, if not to recognize the minuter shades of pathological- difference between morbid growths so superficially situated as those of the mammary gland; at all events to diagnose the malignant from the non-malignant affections of this organ; yet in practice nothing is more difficult in many cases; and it not only requires great experience, but also an intimate acquaintance with the special course and symptoms of each particular disease, to come to a correct conclusion as to its nature. Even with all the light that expe- rience and a careful examination of the characters of the tumor may throw upon the nature of the disease, it will be impossible for the surgeon to avoid occasional errors in their diagnosis. NON-MALIGNANT TUMORS. Mammary tumors may be of a simple or a malignant character. The recogni- tion of the different varieties of simple tumor that affect the breast gland, is principally due to Sir A. Cooper; and this department of surgical pathology has of late years been much extended by the researches of M. Velpeau and Mr. Birkett. The non-malignant tumors of the breast comprise the chronic mammary tumor, the different varieties of cystic growth, the painful tubercle, hydatid cysts, and various forms of fibrous, cartilaginous, and osseous growths. The chronic mammary or adenoid tumor is perhaps the most common variety of these benign structures. It usually occurs as the result of blows, squeezes, or lacteal irritation, and is almost invariably met with in young women under thirty years of age; seldom if ever occurring at a later period than forty; usually in persons otherwise hearty; and most frequently in those of a sanguineous nervous temperament. This tumor is generally of small size, though occasion- ally it may attain the bulk of the fist. On examination after removal, it appears irregularly lobulated, and its cut surface will be found to present a bluish or greyish-white color, which after exposure to the air assumes a rosy tint, and on pressure, drops of a thick creamy fluid will often be seen to exude. Under the microscope it has been found, by Mr. Birkett, to consist of imperfectly developed hypertrophy of the glandular tissue; the terminal cells of which are filled with epithelial scales. This tumor usually commences as a small, movable, finely nodulated growth, attached by a pedicle to one side of the mammary gland; it is hard and incom- pressible, often appears isolated, and not generally painful; it increases slowly, and without discoloring the skin or becoming attached to it, and is often many years in attaining a moderate size. It is often floating as it were in the sub- 750 DISEASES OF THE BREAST. stance of the gland, into which it can be pushed back. These tumors are fre- quently mistaken for cancerous growths, and the diagnosis is often as difficult as it is important; though, in many cases, the otherwise good health of the patient, the mobility of the mass, the absence of all implication of the skin or glands, the want of hardness and of a circumscribed character will usually indi- cate its true nature. The treatment consists in attention to the general health, and the employ- ment of local absorbent remedies. In this way tumors of this description have occasionally disappeared; in some instances they have been known to become spontaneously absorbed after marriage or during pregnancy. If obsti- nate, their dispersion may be facilitated by the occasional application of two or three leeches, followed by inunction of the iodide of lead ointment; and the internal administration of Plummer's pill, and the compound decoction of aloes. In addition to these means, the employment of compression will be found espe- cially serviceable; this may be applied either by means of Arnott's slack air- cushion, or by using a pad to which a spiral spring is attached, and which being compressed by a proper arrangement of bandages across the chest will keep up steady and continued pressure upon the tumor. I have employed this kind of apparatus, which is far less expensive and cumbersome than the air-compressor, in several cases of mammary tumor with great advantage. The advantage attending it is that it can be used in conjunction with absorbent ointments, which cannot be used with the air-bag, as the grease entering into their compo- sition destroys the macintosh cloth of which it is made. In this way absorption may not unfrequently be secured ; and I am disposed to think that not a few of the so-called cases of cancer of the breast that have been reported as having been cured by pressure, were, in reality, instances of the chronic mammary tumor in which absorption had been brought about in this way. Should the growth attain too great a magnitude to admit of absorption by the means that have just been recommended, its excision must be practised. In doing this it is not necessary to remove the whole of the breast, but it will be quite sufficient to extirpate the tumor itself. If the growths implicate the edge of the mam- mary gland, this may be done by two incisions that radiate from the nipple as from a centre, thus inclosing a triangular portion of the breast. If it be movable and be in the substance of the gland itself, it may often be enucleated through a simple incision. It occasionally happens that the chronic mammary tumor becomes the seat of intense neuralgic pains of a very severe and paroxysmal character, attended with very considerable cutaneous sensibility, constituting the form of disease that goes by the name of the painful mammary tumor. This condition most frequently occurs in early life, and in women of an irritable and delicate consti- tution ; it is commonly associated with disorder of the uterine functions, the pain increasing at the catamenial periods, and appearing to be essentially owing to the implication of some of the twigs of the intercosto-humeral nerves in the disease. The treatment of this affection must have special reference to the removal of the neuralgic condition. This is commonly best effected by the internal administration of alteratives and tonics, more particularly of the pre- parations of iron and zinc, with cod-liver oil if necessary, and by the inunction of the iodide of lead ointment, conjoined with belladonna or aconite into the affected breast. In many cases the application of a few leeches, from time to time, more particularly in the vicinity of the axilla, will lessen the neuralgia more effectually than any other plan of treatment; and, in others, again, pres- sure will be found serviceable. If all other means fail, excision of the tumor may in this, as in the last case, ultimately be found necessary. Cystic tumors of the breast are amongst the most common of the non-malig- nant affections of this organ. They may occur in three distinct forms: 1st. As a single unilocular cyst; 2d. As several of these cysts occurring together; and CYSTIC TUMORS. 751 3d. As the cysto-sarcomatous tumor, in which the cystic development appears to be superadded to a structure analogous to that of the chronic mammary tumor. Besides these forms of non-malignant cystic tumor, we occasionally meet with cystic cancer of the breast. The single or unilocular cyst of the female breast, described by Sir B. Brodie as the sero-cystic tumor, and by Sir A. Cooper as a variety of hyatid tumor usually occurs in the form of a small thin sac, about the size of a filbert, con- taining a clear serous fluid, imbedded in the granular substance of the breast, and movable under the skin; most commonly more than one cyst of this kind is present in the breast, though as one attains a greater development than the others, the smaller ones may readily escape detection. These cysts, when single and small, always contain a clear serous fluid, but as they increase in size, or become multiple, their contents may assume a greenish, brown, or blackish tinge. They may continue for a great length of time of small size, but in other cases, again, they gradually increase until they contain several ounces of serum. Sir B. Brodie is of opinion that they are originally formed by a dilatation of the lactiferous tubes, and refers to a preparation in which this position can be demonstrated. The diagnosis of the affection may usually be readily effected by feeling the globular elastic cyst or cysts under the skin; the mammary gland being movable, and not adherent to any of the adjacent structures. In those cases, however, in which the tumor lies deeply, the diagnosis may not so readily be made, more especially from some of the cystic forms of cancer to which I shall by and by have occasion to advert. Whenever the surgeon has any doubt about the existence of fluid in a tumor of the breast, he should introduce an exploring trochar, when, if the disease be cystic, the fluid will be discharged. If the tumor prove to be solid, no ill consequences will result from the simple puncture. Two instances have lately occurred to me, in which, from want of this simple precaution, very excellent surgeons had condemned as cancerous, tumors of the breast that proved to be cystic. Unilocular cysts of the breast occasionally attain an immense size, at the same time that their walls continue thin and supple. In some of these instances, the fluid continues to the last of a truly serous character; in other cases, however, it becomes more or less glairy or mucilaginous, and hence Velpeau has described this variety as the sero-mucous cyst. In other cases, the walls of the cysts have been known to undergo calcareous degeneration. When these cysts attain a very large size, their walls being thin, and the skin covering them tense, they may become translucent, and thus constitute a true hydrocele of the breast, resembling in many respects similar serous tumors that form in the neck. In the majority of instances, as has already been observed, no material change takes place in the cyst, except, perhaps, its gradual increase in size; but in other instances, peculiar changes occur in them, in consequence of which they become filled up by a dense solid growth springing from their interior, at last under- going ulceration, and giving rise to a series of destructive changes. The patho- logical phenomena that accompany these changes have been ably investigated by Sir B. Brodie. He finds that, in the first instance, one or more membranous cysts, containing serum, are formed in the breast; the fluid gradually becomes darker in color, and opaque; after a time, a fibrinous excrescence, of a lobulated or foliated form, springs up into the interior of the cyst, gradually displacing and occasioning absorption of the contained fluid, and, at last, filling up the whole of its interior; and then coming in contact with the capsule by which it is compressed, or with which it may be firmly incorporated, the whole tumor is converted into a solid mass, in which the remains of the cysts still continue to be perceptible. Sir B. Brodie thinks there is reason for believing that a growth of a fibrinous substance takes place from the outer side of the cyst as well, thus adding to the general size of the breast. If one of the larger cysts be laid open, or if the pressure of the intra-cystic growth cause inflammation and ulceration 752 DISEASES OF THE BREAST. of its capsule, this may at last be perforated, and a fungous mass will sprout through it, presenting many of the ordinary symptoms of a malignant growth, being irregular, dark-colored, bleeding readily, and increasing rapidly in size. When such changes as these have taken place, the tumor assumes a formidable character, and will rapidly prove fatal by the induction of exhaustion and hectic. Tumors of this description, composed of cysts having intra-cystic growths sprout- ing from their interior, may attain an immense magnitude and weight. They have been met with of six, eight, or even twelve pounds weight, but the largest is one described by Velpeau, which weighed forty pounds. The various forms of cystic tumor that have just been described, when asso- ciated with the development of fibrinous intra-cystic matter, constitute forms of the so-called cystic sarcoma. Another variety of this disease, however, is not unfrequently met with, in which the sarcomatous or solid element of the tumor preponderates over the cystic part of the growth. In these cases the tumor will be found to be composed of a dense, white, lobulated, or foliated structure, closely resembling that of the chronic mammary tumor, and consisting either of imperfect hypertrophy of the breast-gland, or of the deposit of a fibrinous ma- terial. This mass is studded throughout with a number of small cysts, varying in size from a pin's head to a hazel-nut, and usually containing clear fluid. If some of these cysts increase out of proportion to the rest, the tumor will assume more of the true cystic character. This form of cystic sarcoma usually occurs in women from thirty to thirty-five years of age, as the result of injury or as the remote consequence of some inflam- matory action during lactation. On examining a breast affected in this way, it will be found that the tumor, which may either be confined to one lobe, or im- plicate the whole of the gland, is hard, heavy, and solid to the feel; on careful examination, however, its surface may be felt to be finely nodulated; and, occa- sionally, a larger cyst than usual may be found projecting, which is recognized by its elastic feel and globular shape. The disease is slow in its growth, and does not implicate the adjacent cutaneous or cellular structures; hence, the tumor is movable on the pectoral muscles, and the skin is unattached to it. The axillary glands, also, are not enlarged, at least not to any material extent. The nipple will always be found to be normal in its shape, and not depressed. The treatment of these various forms of cystic and sarcomatous growths varies, according to the size of the cysts, and the quantity of solid matter deposited inside and around them. When the cysts are small, the fluid contents may be let out by puncturing with a small trochar; but a cure cannot usually be effected in this way, as the fluid readily re-accumulates. In such cases as these, Sir B. Brodie has found considerable advantage in the application of stimulating em- brocations, more particularly of one composed of equal parts of camphorated spirit and weak spirit, with one-eighth part of liquor plumbi. In other cases, blistering and the application of the tincture of iodine, may be serviceable. Under these plans of treatment I have several times seen the tumor disappear, occasionally it will suppurate and is thus got rid of. Should, however, these plans of treatment produce no good effect, it may be necessary to remove the whole of the breast affected by the disease. It is better either to leave the tumor and treat it by palliatives, or to remove the whole breast; partial removal of the breast, extirpation of the tumor, with its lobe of the mammary gland, is not usually a very successful operation. Often very severe inflammation of the glands and of the succeeding textures is set up. This I have seen on several occasions, and therefore think it better that the breast should either be left, or removed in toto. Such an operation, however, should not be undertaken in the early stages, as the tumor may continue for many years without seriously troubling or endangering the patient, and may perhaps eventually undergo atrophy or absorption. If, however, it show a disposition to increase, to become troublesome by its bulk, or painful, it should then certainly be extirpated, and MALIGNANT TUMORS OF THE BREAST. 753 this operation may always be performed with a good prospect of success, inas- much as the disease is not malignant, and does not tend to contaminate the constitution. It is a remarkable fact, however, which has been adverted to by Lawrence and Brodie, that even though the whole of the breast be extirpated, a similar affection occasionally recurs in the cicatrix, requiring subsequent ope- ration ; and then, perhaps, being permanently eradicated. This must either be owing to some portion of the cystic structure having been left in the first opera- tion, or to the development of new cysts in the site of the former; but to which cause it is referable is still uncertain. A still more remarkable circumstance connected with these tumors is, that after their removal a recurrence of cancer will occasionally take place in the cicatrix. The repeated recurrence of these cystic tumors is very remarkable. Mr. Caesar Hawkins relates a case in which the growths had to be removed eight times for as many recurrences. Besides these tumors, the breast is occasionally the seat of other morbid orowths; as for instance, fibrous, osseous, and cartilaginous masses have been met with in this situation. All these affections, however, are of extremely rare occurrence, and when they form it is almost impossible to determine their true nature until after removal. Their extirpation is usually practised on account of the obscurity attending the diagnosis, and the fact of their commonly being mistaken for cancerous growths. Sir A. Cooper describes a scrofulous tumor of the breast, the precise nature of which is not very apparent from the account given by that surgeon. It is not improbable, however, that it is of a tuberculous character; and Velpeau states that he has found tubercles occurring in the breast in two forms. In the first, principally deposited in the skin and subcutaneous cellular tissue; and in the other, of a fibro-tuberculous character, affecting the gland itself. Hydatids of the breast are of rare occurrence, and have been principally described by Sir A. Cooper, and cases have been related by Graefe and others. These hydatid tumors are so excessively rare and obscure that their true nature would not in all probability be suspected until after removal. They present the ordinary characters of a deeply-seated cyst, with fluctuation and some indu- ration round the globular swelling, and an absence of pain. In such a case as this, an incision into the tumor will cause the escape of the acephalocysts, and the ultimate suppuration of the cavity in which they lodged, which will gradu- ally cicatrize. In some rare cases, tumors containing foetal remains have been met with in the breast; these cases, however, are rather matters of surgical curiosity than of practical importance. MALIGNANT TUMORS OF THE BREAST. All the various forms of cancer have been met with in the breast; scirrhus, however, occurs with far greater frequency than any of the other varieties. Occasionally the encephaloid form of the disease is met with, but colloid very rarely occurs; indeed, the only case of colloid of the mammary gland, with which I am acquainted, is that in a preparation in the University College Museum. Cancer of the breast, whatever form it assume, is invariably pri- mary : it may affect one lobe only, or be infiltrated into the whole gland; and it may commence in the nipple or in the skin covering the breast. Most fre- quently only one side is affected, but in some cases both mammary glands are implicated. . Scirrhus is that form of cancer that is commonly met with in the breast; it may occur in several ways, either as affecting the nipple, as being deposited in the form of an intra-mammary tumor, or as infiltrating the whole substance of the oroan. It most commonly commences as a circumscribed tumor of small size, at°first perhaps smooth and round, hard and indolent in its character, with little or no pain; it is readily movable, may be situated in one lobe, and at- 48 754 DISEASES OF THE BREAST. tached perhaps to the rest of the gland by a distinct pedicle. As it increases in size, it becomes hard, knobbed, and irregular, perhaps presenting a finely- granular feel, and becoming fixed to the gland and subjacent parts. When the disease begins as scirrhous infiltration of the breast, the gland is from the first, hard, rugged, irregular, nodulated, and heavy; often somewhat square in shape, and early accompanied by adhesions to subjacent parts. In other cases again, the development of the scirrhous mass is accompanied by a corresponding atrophy of the mammary gland, which becomes shrivelled and disappears en- tirely. In some instances rather large cysts may form in connection with these scirrhous masses. In a woman, whose breast I lately removed, for what was supposed to be cystic sarcoma, but proved after the operation to be a scirrhous tumor, the mass contained several cysts as large as cherries, filled with dark or greenish fluid, and projecting from its surface; and in a lady who is at present under my care for scirrhus of the breast, a tumor as large as a pigeon's egg, containing sanguinolent fluid, formed on the surface of the tumor. As the swelling increases in size, it has a tendency to become more fixed to the subjacent parts, becoming adherent to the pectoral muscles, and incorporated with the cellular tissue at the border of the axilla. The tumor also begins to form a distinct external projection, becomes more irregular in shape, is the seat of severe pain, more particularly at night, and is usually covered by a plexus of blue and dilated veins. The ordinary symptoms of cancerous cachexy now begin to set in, and the disease then makes still more rapid progress. The tumor may in some cases remain for a great length of time without im- plicating the skin, but most commonly after it has existed for a few months this tissue becomes more or less involved in the morbid action. Instead of being loose and movable over the surface of the tumor, it will be found, on being pinched up between the fingers, to dimple at one part, where it may be felt to be attached by a kind of cord-like process to the tumor beneath it. After a time, that portion of the skin which first became fixed in this way, acquires a reddish or purplish color, and is covered with thin, scaly, epidermic desquama- tions, and becomes permeated by a number of small ramifying vessels. A crack or fissure eventually forms in this; a small exudation of a mucous fluid takes place, which dries into a scab; under this, ulcerative action sets in, which spee- dily assumes the ordinary characters of a scirrhous ulcer, having hard, elevated, and everted edges, a greyish-green or foul surface, and discharging a quantity of very fetid pus. In some cases ulceration may take place at several points, and thus the whole surface of the breast become converted into one immense chasm, which may even extend up into the axilla. The skin, when affected, often assumes a red, glazed, hard, and brawny cha- racter, being shining, and as if greasy upon the surface, having its pores en- larged, and enveloping the side of the chest in a kind of stiff, solid casing, attended usually by much pain, considerable oedema of the arm, and an aggra- vated form of constitutional cachexy; ulceration at last takes place in this har- dened mass, and then speedily destroys the patient. In other cases, the integu- ments covering the breast become early contaminated by the cancerous matter assuming a hard, leathery character, or feeling brawny and infiltrated; often without discoloration, but presenting a hypertrophied appearance, the pores being enlarged, and the interspaces between them increased. In other cases the infiltrated skin assumes a brownish or purplish color. The pain is in many cases but trifling in the early stages of the affection, so much so indeed, that it is the tumor, often accidentally noticed, that first excites alarm; as it increases, however, the suffering becomes severe, more par- ticularly at night, is greatly aggravated by handling the diseased mass, and chiefly extends up to the shoulder and down the arm. The pain usually be- comes most severe about the time when the skin is first implicated; but as the CANCER OF THE BREAST. 755 cutaneous infiltration goes on, it gradually lessens, owing probably to the destruction of the cutaneous nerves. Retraction of the nipple commonly commences about the same time that the skin is implicated; it appears to be owing to the glandular substance becoming involved in the mass of the tumor, and thus giving rise to shortening of the lac- teal ducts, in consequence of which, by the projection forwards of the general mass of the breast, the nipple appears to become completely buried This sign has, I think, received more importance than it deserves in connexion with can- cer, as it does not occur in all cases of malignant disease, and is occasionally met with in simple mammary tumors. The axillary glands usually become enlarged early in the disease, and may attain a greater size than that of the original tumor, and on close examination a kind of indurated cord may be felt extending in the course of the absorbents, from the edge of the pectoral muscle to the axilla. After a time the supra or sub-clavicular glands may likewise become complicated. In fact, the whole of the glandular structures in the vicinity of the shoulder undergo cancerous infil- tration. When this is the case, the pressure that is exercised upon the axillary vein may occasion oedema of the arm and hand. The glandular infiltration usually increases rapidly after the skin has become implicated. As the scirrhus extends, it gradually affects the subjacent muscles, cellular tissue, the ribs, and at last the pleura, commonly giving rise eventually to hydro- thorax or secondary visceral deposits. In many instances, however, the disease proves fatal by the induction of exhaustion. The constitutional cachexy is in many cases not very distinctly marked, until after the skin has become involved; but then it rapidly increases, more especially when ulceration takes place. In- deed the cancerous degeneration of the skin may be looked upon as an epoch of peculiar importance in scirrhus of the breast, as it is at this period that the pain increases, that the lymphatic system becomes infected, and that the constitution becomes distinctly poisoned. The duration of life after the occurrence of scirrhus of the breast, varies greatly, so much so that the disease may be considered as assuming an acute and a chronic form. The acute variety principally occurs in ruddy and plethoric women, and commonly proves fatal in a few months. In those who are of a more feeble and delicate constitution, the disease, as a general rule, takes a slower course. Sir A. Cooper states that the disease, on an average, is from two to three years in growing, and from six months to two years in destroying life, after being fully formed. In this estimate, which is probably correct, Dr. Walshe agrees, so that the average duration of life in cancer of the breast would probably be about three years. As a general rule, the progress of scirrhus is slower in old people, in whom it occasionally gives rise to a kind of atrophy of the breast, with shrinking and induration of the tumor. There are many instances on record, however, in which cancer of the breast has existed for a far longer period than has just been mentioned, for ten, twelve, or even as in a case related by Sir B. Brodie, for twenty-five years. After removal, scirrhus of the mamma presents considerable variety in appear- ance. In the majority of instances it occurs as a peculiarly hard knobbed and irregular mass, creaking under the knife when cut, and presenting on section a greyish or bluish-grey, semi-transparent surface, traversed in various directions by bands of a more opaque character, and exuding on pressure a thin reddish juice. In many instances masses of an opaque character, and yellowish tint, may be seen in the midst of the tumor. These, which look like tuberculous deposits, consist in reality of fatty degeneration of the scirrhous structure. In other cases again, on pressing the tumor, small drops of a thick creamy fluid will appear to exude at various points. This appears to be the inspissated and altered secretion of the gland retained in the ducts. Cysts are occasionally, though rarely, met with in scirrhus of the breast; these are usually small, and 756 DISEASES OF THE BREAST. contain clear fluid, being deeply imbedded in the substance of the tumor; in other cases again, they may be large and globular, and filled with a bloody or dark-green liquid. The microscopical characters of scirrhus of the breast, are such as are represented in fig. 148. Encephaloid of the mammary gland is by no means of such common occur- rence as scirrhus, but yet all the varieties of this form of cancer have been met with in the breast; and fungus haematodes has been seen to spring from the bottom of cystoid growths previously developed in this region. Encephaloid of the breast may sometimes acquire a considerable size; thus, Cruveilhier relates a case in which the tumor weighed nearly twelve pounds. The structure of this disease does not differ from that of the same affection in other situations; both the hard and the soft varieties may be met with, and in some advanced cases the true fungous growths occur. Encephaloid usually begins deeply in the substance of the breast, as a soft globular tumor, which rapidly increases in bulk; the integuments covering it are not at first adherent, but are usually pushed before it, and speedily become permeated by a largely ramified net-work of veins. The mass feels as if cdmposed of several soft and rounded tumors, which communicate an obscurely fluctuating sensation, causing perhaps the sur- geon to mistake the growth for a cystic formation, or an abscess. The breast now rapidly assumes a very prominent and conical form; the skin covering it at its most projecting part becomes thinned and reddened, and at last gives way, leaving a large circular ulcer, from which a fungous mass of greyish or reddish- brown color speedily sprouts up, with a good deal of discharge of' a foul, bloody, and offensive character. From this, disintegrated masses are occasionally detached by a kind of sloughing action, and cases may even occur in which the whole of the fungous protrusion sloughs away, and cicatrization taking place, a tolerably perfect cure may result. These cases, however, are so rare, as scarcely to influence our prognosis of the necessarily fatal character of the affection. Implication of the glandular structures in the vicinity of the tumor, followed by constitutional cachexy, occurs in this as in true scirrhus of the breast. The progress of the disease is always extremely rapid, more particularly in young and otherwise bealthy subjects. Colloid cancer and melanosis of the breast occur so rarely, and only in con- nection with the other varieties of the disease, that they can merely be looked upon as presenting points of pathological interest. The causes of cancer of the breast are usually of an extremely obscure character. The most marked circumstance that influences its occurrence is certainly sex, it being, as is well known, almost entirely confined to women; yet instances in which this affection is met with in the male breast occasionally occur. Its pecu- liar frequency in the female may possibly be owing to the great and sudden alternations of the functional activity of the breast in women. The changes that are impressed upon this organ at puberty and during pregnancy, the various alternations it undergoes, and inflammatory affections to which it is subject during lactation, the frequent irritation to which it is exposed by sympathizing with uterine derangement, and the diminution in its vital activity that takes place at the change of life, are sufficient to explain the great liability of this organ to disease generally; and may not improbably give a clue to the reason why it is so peculiarly the seat of cancer in women. The age at which cancer of the breast most frequently occurs is between the thirtieth and fiftieth year. According to Birkett, it is most commonly met with between the ages of forty- five and fifty; a period of life that is popularly looked upon as specially ob- noxious to this malady. At these ages, cancer of the breast usually affects the form of scirrhus. When occurring, as it very rarely does, in early life, it more frequently assumes the encephaloid character. I have, however, removed a scirrhous breast from an unmarried woman of twenty-three years of age. In elderly women, scirrhus also is the prevalent form, though I have seen two or DIAGNOSIS OF CANCER OF THE BREAST. 757 three instances of encephaloid at an advanced period of life; one case, in a woman upwards of seventy years of age. Indeed, cancer, in either form, may affect this organ up to the latest periods to which life is prolonged. Married women are said to be more liable than single ones to cancer of the breast; it may, however, fairly be doubted whether they are proportionately so, and it is a common belief, founded, I believe, in some degree on truth, that the disease is most common in those women who have not borne children. Injuries inflicted upon the breast, such as blows, squeezes, &c, are commonly referred to, and are greatly dreaded by women, as the causes of cancer. That they might be so in constitutions otherwise predisposed to the affection, does not appear improbable, and that they are so in reality, I have not the least doubt. The number of instances that have fallen under my observation, in which a blow or squeeze of the breast has speedily been followed by the appear- ance of a cancerous tumor in it, leave no doubt whatever on my mind of the truth of the popular belief that associates the injury with the disease, in the relation of cause and effect. Lacteal inflammations are likewise frequently supposed to tend to the production of cancer of the breast. Of this doctrine I think that we do not possess at present sufficient proof, though it appears to me highly probable that disturbances of the functions of the organ during lactation may predispose to the occurrence of this disease. The diagnosis of cancer of the breast from other diseases affecting this organ, is of the first importance, and is attended by corresponding difficulties. The great point is to determine whether the tumor of the breast is of a cancerous character or not; beyond this it matters little in practice that the surgeon should go — and, indeed, except in some of the forms of cystic disease of this organ, few practitioners would feel disposed to endeavor to carry their diagnosis beyond this point. The great and essential difficulty in determining the nature of a tumor of the breast consists in the fact of the same signs being more or less common to many growths in this region; a hard, circumscribed, indolent mass, chronic in its progress, with a certain amount of pain, being the usual characteristics presented by all solid mammary tumors; and though in nine cases out of ten, a tumor presenting these characters, which has existed for a year or more, in an elderly woman, and has resisted ordinary absorbent and alterative treatment, is of a scirrhous character, yet instances of the reverse occasionally occur. Nothing can better exemplify the difficulty of diagnosis in tumors of the breast, than the circumstance, which is not unfrequently witnessed, that after the removal of the diseased mass, its section, and careful examination, surgeons of equal experience will differ as to whether it is malig- nant or not, and to what class of affections to refer it; and, indeed, in many of these cases it is impossible to ascertain its precise nature without having recourse to microscopical observation. It is extremely difficult to lay down any definite rules of diagnosis, by which the question as to the malignancy of a tumor of the breast can be solved. In the majority of cases of cystic growth in this region there is little difficulty; the existence of cysts of sufficient size to be readily felt or seen through the skin, being generally characteristic of the malignant cystic growths. It must be borne in mind, however, that cases, such as one to which allusion has already been made, may occur in which cysts are conjoined with cancerous development. The diagnosis between cystic sarcoma and some forms of cystic cancer of the breast is not always easy, indeed may be impracticable, and can only be deter- mined after removal by microscopical examination. I have lately had a patient in the hospital fifty-nine years of age, in whose breast a hard tumor, as large as half an orange, had existed for five years; it was perfectly and freely movable, unconnected in any way with the skin, there was no retraction of the nipple, and no lancinating pains. On its upper side, several large cysts could be felt, and seen through the skin. On examination after removal, it was found to be 758 DISEASES OF THE BREAST. encysted scirrhus, with large cysts, the size of cherries, containing bloody and yellow fluid. The only very suspicious circumstances here were the age of the patient, and the existence of one small indurated gland in the axilla. In these cases of doubt, the safer plan is always to make an exploratory puncture, and, if necessary, to examine under the microscope the contents with- drawn by the groove in the needle or by the trochar; indeed, if there is the slightest doubt as to the nature of the tumor, this exploratory puncture should never be omitted before its removal is determined upon. I have more than once seen tumors pronounced positively to be scirrhous, and for which ampu- tation of the breast had been recommended, turn out to be cystic, and disappear entirely as their contents were withdrawn. KON-MALIGNANT tumors. SCIRRHOUS TUMORS. Feel. — Moderately hard, nodulated, irre-gular in shape, occasionally more or less lobed, not very distinctly circumscribed, sometimes elastic in parts. Mobility is considerable, though occa-sionally there is a deep pedunculated attachment. Skin of the natural color throughout, though thinned and expanded, with the tumor lying close beneath it. Only implicated in the advanced stage of cystic sarcoma. Nipple usually not retracted. Veins of the skin not much dilated. Pain often moderate, if severe, continuous or of a neuralgic character, much in-creased by handling. Axillary glands of usual size, or but slightly enlarged and movable. Lymphatics not affected; supra-clavicular glands not affected. No constitutional infection. Feel of a stony hardness, knobby and distinctly circumscribed, or else some-what square, and occupying the whole of the substance of the gland. Mobility at first considerable, but soon becomes fixed to the deeper structures by a broad attachment. Skin becomes early implicated — at first dimpled, then red or purple, and in other cases brawny and leather-like, so that it does not admit of being pinched up into folds, or nodulated, purpled-red masses form in it. Nipple usually retracted. Veins of the skin very greatly dilated. Pain severe and lancinating, especially at night after handling, and when the skin is implicated, but not continuous. Axillary glands enlarged, indurated, and fixed. Indurated mass of lymphatics under and parallel to edge of the pec-toral, stretching into the axilla; supra-clavicular glands enlarged. Constitutional cachexy as disease advances. Between cancer and the ordinary solid tumors of the breast, the diagnosis is often extremely difficult, but we may arrange the chief signs of the two forms of disease in distinct groups, when, by comparing them together, the differences may be more clearly seen. (See Table, above.) Treatment of cancer of the breast.—In cases of cancer of the breast, the first question that presents itself to the surgeon, is whether any plan of treatment short of the removal of the tumor holds out a prospect of cure, or even of relief; and if not, whether the extirpation of the cancerous breast can be undertaken with the prospect of ridding the patient of an otherwise fatal dis- ease; or at least of prolonging her existence. To these questions the remarks made at page 406 et seq., on the general treatment of cancer, may be considered applicable. The management of cancer of the breast, however, involves so many special considerations of importance that it becomes necessary to consider its bearings somewhat in detail. No constitutional means appear to be of the slightest service in arresting, and still less in removing, cancerous tumors of the breast. The advantages stated to have been derived from the use of arsenic, conium, iron, and various preparations of mercury, have not been borne out by experience; and indeed it TREATMENT OF CANCER OF THE BREAST. 759 may be stated generally that these and all other known remedies are perfectly valueless in the curative treatment of this disease. Compression by various means, whether by plasters, as employed by Young; by agaric, as used by Recamier; by the spring-pads of Tanchou, or the slack air-cushion of Dr. Arnott, has been much praised, not only as a palliative, but as a curative means of treatment in this disease; and cases are recorded, which, however, even the warmest advocates of this plan of treatment are forced to admit to be altogether exceptional, in which the employment of this means has been stated to have effected a complete removal of the tumor. But although I am not prepared to deny that hard and chronic tumors of the breast may have become absorbed during the employment of this treatment; and indeed I have had occasion to observe this in my own practice, in cases of chronic mammary growth; I think that evidence is altogether wanting to show that an undoubted case of cancer of the breast has ever been cured by this means. And notwithstanding the high authority with which some of these alleged cases of cancer have been brought before the profession, no positive proof has been adduced to show that the tumor that was observed was really and truly of a cancerous character, and that it may not have been either a chronic mammary tumor, or an encysted abscess of the breast. Every practical surgeon well knows that it is utterly impossible in the present state of science to diagnose in many cases with complete certainty the true nature of a tumor of the breast, and must frequently have witnessed cases in which, after extir- pation, the morbid growth has been found to be of a different character to what had originally been supposed. I am acquainted with at least eight or ten cases in which some of the most experienced surgeons, both in this country and in Paris, have amputated the breast, for supposed scirrhus, when after removal, it was found simply to have been the seat of a chronic abscess, with very dense walls. And with regard to hard, chronic, and indolent tumors of the breast, few surgeons will hazard a positive diagnosis, as to whether it is of a scirrhous character or not, until they have actually seen a section of it; and even then how often does it not happen that men of equal experience will differ in the judgment they pronounce as to its nature. For these reasons it is impossible not to receive with the utmost hesitation the cases of supposed cancer of the breast reported as cured by the advocates of compression, and not to suspect that the cases recorded by these gentlemen as instances of the successful employment of this plan of treatment, may have been other chronic tumors of the breast, than those of a cancerous character. But though I think that there is no evidence before the profession to prove the utility of compression as a curative agent in cancer of the breast, I think that when practised with Dr. Arnott's slack air-cushion, or Tanchou's spring- pad, it is of considerable value as a palliative in some of the earlier stages of this disease; when it may undoubtedly occasionally arrest its progress for a time, diminish the size of the swelling, and lessen the violence of those attacks of lancinating pain which are so distressing to the patient. In conjunction with the pressure, much relief to suffering may be afforded by the use of bella- donna plasters, or of atropine or aconite inunctions, together with the internal exhibition of conium. In the advanced stages of the disease, however, when the skin is involved, the pressure is often unbearable, increasing the pain, and acting as a source of irritation to the patient. In some cases of this kind, in which the slack air-cushion could not be borne, I have seen relief afforded by moderate pressure with thick layers of amadou, supported by an elastic bandage, belladonna or conium in powder being dusted on the innermost layer of amadou. A very thin gutta-percha shield, moulded to the part, may sometimes be advan- tageously applied over this, and kept on by turns of an elastic roller. AVhen the skin is implicated and very tender, the application of bread poultices made with belladonna and lead lotion is of use. When the disease has run into an 760 DISEASES OF THE BREAST. ulcerated stage, the internal administration of conium, so as to blunt the sensi- bility, and the local application of chlorinated lotions to lessen the fetor, together with the application of the watery extract of opium or of belladonna are of much use. In such cases as these, the application of caustics has been greatly vaunted, and portions of the diseased surface may be cleansed or removed by these means. Caustics employed in accordance with the principles laid down at p. 407 may occasionally be advantageously employed in the treatment of cancer of the breast, when excision is not practicable. The constitutional and ordinary local treatment of cancer of the breast being thus, at the most, of a palliative character, the question of operation always presents itself at last. The objects proposed by an operation are in the fir^t place, by the extirpation of the diseased breast, to prevent constitutional infec- tion, and thus permanently to free the patient from her necessarily fatal affec- tion ; or, failing in this, to retard the progress of the constitutional infection, and thus at least to prolong existence. How far these objects are attained by amputation of the cancerous breast is a subject of important inquiry to the surgeon. The operation has of late been discountenanced by many excellent pathologists; not so much from any intrinsic danger it may possess, for although occasionally fatal from erysipelas or some similar accidental complication, there is nothing specially hazardous about it; nor from its being now, as formerly, open to the objection of subjecting the patient to unnecessary pain, all suffering during its performance being prevented by anesthetics, and little inconvenience being experienced at subsequent dressings, which are usually of a nearly pain- less character; but the great objection lies in the fact of the disease, in many cases, returning with equal, and in others perhaps with greater rapidity after the operation, than if none had been performed. The principal points in connection with the operation appear to resolve them- selves into two questions:—1st. Whether, in any cases of cancer of the breast, constitutional infection may be prevented by amputation of that organ; and if so, under what circumstances this will most probably happen ? And, 2d. Although the disease may eventually return in the part or elsewhere, whether excision may not arrest the rapidity of the fatal termination ? In answer to the first question, it is not easy to give a very definite reply. Nothing shows more clearly the worthlessness of so-called surgical statistics than the discrepancy that exists between those that have been published as exhibiting the liability to relapse of cancer after operation. Thus, Hill states, that out of 88 cancers on which he had operated at least two years before the return was made, there were only 10 relapses, and 2 deaths; whilst Alexander Munro states, that out of 60 cancers which he had seen removed, in only 4 patients was there no relapse at the end of the second year. Boyer only saved 1 in 25, and Macfarlane gives a still more unfavorable account of his practice; for he says, that out of 32 cases of cancer operated upon by himself, there was not one instance of radical cure; and of 80 other cases that he was acquainted with, the result was in every instance unfavorable. Warren, on the other hand, saved one in 3; and Cooper 1 in 4. Amidst such conflicting statements as these, it is clearly impossible to eliminate more than the general fact which is well known to every surgeon, that in a large number of the cases of cancer that are operated upon, there is a tolerably speedy return of the disease. In these cases there are, however, many points to be taken into account, that gross statis- tics can take no cognizance of; much being necessarily dependent upon the skill with which the operation is performed, as well as upon the care employed by the surgeon to cut widely of the disease, and to extirpate completely not only the whole of the morbid mass, but those tissues in its neighborhood that might be supposed to be implicated. In many of the cases, also, it is by no means improbable that the practice, at OPERATION IN CANCER OF THE BREAST. 761 one time pretty generally followed, may have been adopted, of merely extir- pating the tumor without removing the whole of the breast. I am, therefore, disposed to look upon any deductions based upon the statistics of such men as Hill, Macfarlane, and Benedict as of very little value when applied to the surgery of the present day. It would, however, appear from the result of those inquiries, that in a certain proportion of cases, whatever the precise ratio be, and this is still undetermined, the disease may be effectually removed by extirpation of the breast. As the second question, — whether as a general rule life may not be pro- longed by the performance of the operation,—it would appear, if the statistics collected by Leroy D'Etiolles are accurate, that hitherto it has not. Dr. Walshe comes to the conclusion that the operation cannot as a general rule be regarded as a means of prolonging life, but that in the majority of cases death is hastened by such interference. Sir A. Cooper and Sir B. Brodie both agree that in the majority of cases, the disease returns in two or three years after the operation, and then kills the patient. But though the general result of a statistical inquiry into this subject, based upon the imperfect materials and probably very incorrect figures at present before the profession, leads to the conclusion that operations for cancer of the breast, when indiscriminately performed, have hitherto not only failed to cure the disease, but actually in a great number of cases hastened its fatal termina- tion, yet it must be borne in mind that instances do occur in which life is cer- tainly prolonged by this means considerably beyond its average duration in cancer of the breast. Thus, Callaway operated on a case in which no return took place for twenty-two years. Velpeau states that he has removed encepha- loid tumors of the breast, and that the patient has remained free from the dis- ease for eight or ten years. Sir B. Brodie and other surgeons relate similar instances in which the patient's life has been prolonged after the performance of the operation; and the experience of the most eminent practical surgeons is decidedly in favor of having recourse to it under certain circumstances. The only reliable statistics that we possess on the relative duration of life in cases of cancer of the breast, with or without operation, are those collected by Mr. Paget. He states that of 139 cases, 75 were not submitted to operation; of these the average duration of life was 48 months. Of 64 operated on the corresponding average has been a little more than 52 months. In the first two years of the disease the proportion of deaths was much less in those operated on than in those who were left, — being in the former less than 11 per cent., in the latter more than 30 per cent. The longest duration of life in a case not operated on was 18 years; in those operated on, a little more than 12 years. There is, however, another point of view from which these operations may be considered; for even if they do not prolong life, they may greatly improve the patient's condition, and place her in a state of comparative comfort during the remainder of her existence. Thus she may be suffering so much pain from the local affection, or if it be ulcerated, be so much affected by the fetor of the dis- charges, that she may be placed in a position of far greater comfort by having the local source of disease and irritation removed; and though she die eventually of cancer, it may be with much less suffering to herself and others for her to be carried off by secondary deposits in the lungs or liver, than to be worn out by the external affection. In considering the propriety of operating in cancer of the breast, it is of the utmost importance to determine those cases in which the operation may possibly be the means of preserving or prolonging life, from those in which there is no prospect of its being of any service, or in which indeed it must inevitably hasten the patient's death. Whatever the value of statistics may be in determining the question as to whether in cases of cancer of the breast generally, the opera- 762 DISEASES OF THE BREAST. tion will effect a cure or prolong life, they are not equally valuable in their application to individual cases. When a surgeon is called for his opinion re- specting the propriety of amputating the breast of the patient before him, it is not sufficient for him to be able to state what the general result of the opera- tion may be, but he must be able to satisfy himself whether the particular in- stance under consideration may not be one of those cases, exceptional perhaps, in which there is a fair probability of the operation extirpating the disease entirely from the system, or at all events prolonging the patient's existence. In order to do this it is necessary to endeavor to lay down some rules that may guide us in selecting those cases in which the operation may be advantageously done, and in setting aside others in which we know that it will almost to a cer- tainty hasten the patient's death. And indeed it is the absence of all such con- siderations in general statistical investigations into the results of operation for cancer, that deprives them of much of their value as guides in actual practice. Though nothing can be more unsurgical or improper than the indiscriminate extirpation of all cancerous tumors of the breast from every patient who may present herself, in whatever stage of the disease; and though such a practice would doubtless be followed by fully as disastrous results as those that occurred to Macfarlane, Benedict, and others; yet there can be little doubt that a sur- geon who would employ a certain principle of selection, would obtain a very different and far more successful result in his practice. Sir B. Brodie has very clearly and succinctly pointed out the most important circumstances by which the question as to the propriety of operating in these cases should be deter- mined. Before doing so, he very justly dwells on the fact that in many cases the operation may fail, and the disease speedily recur through the negligence of the surgeon in leaving behind portions of the gland, slices of the tumor, or contaminated tissues, and that thus the operation may receive discredit, for what is in reality the fault of the surgeon who performed it. With reference to operations, cancerous diseases of the breast may be divided into three classes: — 1st. Those in which it is the duty of the surgeon to dis- countenance excision; 2d. Those in which operation is of doubtful expediency; and 3d. Those in which it is the duty of the surgeon to recommend it. 1st. Cases unfit for operation. — In this class we may include the following conditions: (1) Those cases in which there is strongly-marked constitutional cachexy; (2) When both breasts are involved; (3) When there are secondary deposits in internal organs; (4) When the glands under, and especially above the clavicle are much enlarged; (5) If the tumor be adherent to the ribs and intercostal muscles; (6) When the skin is hard, brawny, and infiltrated, of a reddish-brown color, having a hard, leathery feel, or a greasy, glazed appearance; (7) If the tumor is rapidly growing in a patient with a strong hereditary taint; (8) If extensively ulcerated and fungating. 2d. Doubtful cases. — (1) If the patient is aged, weak, or anemic, and the tumor large, it is seldom expedient to operate, as the shock may destroy life; (2) When the skin is merely dimpled in by a kind of pedicle passing from the tumor to its under surface, an operation may be performed unless other circum- stances should contra-indicate it, but in such cases it is necessary widely to ex- cise the integument surrounding the attached point. The cancer cells, as I have more than once had occasion to observe, will be found to have diffused them- selves extensively through the neighboring skin, which, to the naked eye and to the touch, has a perfectly healthy appearance, the tumor being surrounded by a kind of halo or atmosphere of cancer infiltration; (3) When there is but moderate enlargement of the axillary glands, which are so situated as to admit of removal, the operation may be performed; (4) When the cancer is ulcerated, it is seldom proper to operate, but if all other conditions are favorable, this even need not in some special cases be a bar. As Sir B. Brodie has pointed out, the OPERATION IN CANCER OF THE BREAST. 763 patient's existence may sometimes in these cases be prolonged, and her comfort materially increased, by the removal of the diseased and ulcerated mass. 3d. Cases admitting of operation. — The exclusion of all the cases that fall under the preceding categories will necessarily limit very materially those in which an operation may be undertaken; it can, however, be performed with every prospect of its being advantageous to the patient, if the tumor be of moderate size, slow or nearly stationary in its growth, unconnected with or at least merely attached by a pedicle to the skin, pretty distinctly circumscribed, movable on the subjacent parts, and not complicated by enlarged glands in the axilla or elsewhere. The patient has an especially good prospect of recovery, according to Brodie, if the disease be seated in the nipple. In all cases when an operation is undertaken, the whole of the breast should be removed, and the contiguous tissues pretty widely excised. The integuments being loose in this situation, readily come together even after considerable loss of substance. When the tumor is pediculated, only being attached to the gland at one point, some surgeons have recommended that it alone should be extirpated, the breast being left. This practice, however, is not a safe one; I have seen it followed by a speedy relapse, and should certainly always be disposed to extirpate the whole of the organ in this, as in every case of cancer of the breast. When once a tumor of the breast has been ascertained to be of a cancerous character, the sooner it is removed the better, unless one of the special reasons adverse to operation that have just been adverted to should exist. I cannot conceive that any good can come of delay in these cases. The disease (for reasons stated at p. 410) appears in the early stages often to be entirely local; there is no evidence of constitutional infection, but if the operation be delayed the skin speedily becomes implicated, the axillary glands enlarge, and cancerous cachexy sets in. When the operation is performed, the whole of the breast and the surrounding cellulo-adipose structures should be freely removed, as there is often a halo of cancer deposit around the morbid mass, in tissues apparently healthy. Relapse of cancer after operation may take place in two ways; either in the vicinity of the part operated upon, or in some internal organ. When recurring in the neighborhood of the previously affected part, it is probably owing to the cancer-cells having diffused themselves so widely into the skin, the subcutaneous cellular tissue and muscles, or neighboring lymphatic glands, that after the removal of the tumor these cells become the germs of new growths. Under these circumstances it may recur in the cicatrix and then implicate the glands; or, in the glands, without the cicatrix having been previously affected. In local relapse of this kind, it often happens that the disease so reproduced, runs its course more rapidly than if no operation had been done; the increased action set up in the part during the healing process appearing to give augmented force to the reproductive energy of the cancerous growths. In some cases it even returns in the cicatrix before cicatrization is completed, the ulcerated surface then assuming the ordinary character of the cancerous ulcer. In other cases some weeks or months after the cicatrix is fully formed, it assumes a dusky red or purplish tinge, becoming hard, stony, and nodulated at points; these nodules being round or oval, often very numerous, and varying in size from a pin's head to a pigeon's egg, studding the whole length and breadth of the cicatrix, and at last running into true cancerous ulceration. Under such circumstances as these the only hope of prolonging the patient's life lies in the speedy excision of the whole of the diseased structures, provided there be no deep affection of the glands, or evidence of internal secondary deposit. But if the axillary glands be much enlarged, either alone or together, with recurrent disease in the cicatrix, or if there be any sign of internal cancer, further operations will be improper. 764 DISEASES OF THE BREAST. AMPUTATION OF THE BREAST. The operation for the removal of a breast, whether affected with cancer or other disease, may be performed in the following way:—The patient should lie upon a table, with the arm hanging over the side, and held by an assistant. If the tumor be large, and the loss of blood a matter of much consequence, another assistant should compressJlie subclavian artery on the first rib. If the veins about the part be much dilated, measures should be taken to arrest tho flow of blood from them, as it may sometimes be dangerously profuse; indeed, South relates the case of a patient who died from this cause, during the opera- tion. An oblique elliptical incision, of sufficient length, should then be made, first below, and next above the nipple, so as to include a sufficient quantity of integument. The dissection should then be rapidly carried down, by a few strokes of the scalpel, to the pectoral muscle, and the breast removed from the cellular bed in which it lies. Some surgeons extirpate the breast by a perpen- dicular, others by a transverse incision. I think that an oblique incision fol- lowing the course of the fibres of the great pectoral is most convenient, as it enables the surgeon, if necessary, to extend the cut into the axilla for the removal of enlarged glands, and after cicatrization, allows of the movements of the arm without undue traction. After the removal of the diseased breast, it and the tumor, as well as the whole interior of the wound, must be carefully examined, in order to ascertain that no slices of morbid tissue have been left behind; if so, they must be freely cut out, and if, as sometimes happens, the growth is rather firmly adherent to the pectoral muscle, or subjacent structures, portions of these must also be removed. Should it be found that there are any enlarged glands in the axilla, they may be extirpated, either by extending the wound upwards in this region, or by making a separate incision into the axilla, and carefully dissecting them out. In doing this, the edge and point of the scalpel should be very carefully used, and the glands rather teased out with the handle of the knife and fingers, so as to avoid the risk of hemorrhage, which is apt to be troublesome in this situation. The extirpation of enlarged axillary glands is the most troublesome part of operations on the breast, as they often extend much higher into the axilla, and under the edge of the pectoral than would at first appear. When exposed, they may be seized with a double hook or artery-forceps well drawn down, and then enucleated as far as practicable with the fingers, aided by a few cautious touches with the edge of the knife. The less the point is used deep in the axilla, the better for the patient. Should the glandular mass extend high up, coming into close relation with the axillary vessels, it would not be prudent to attempt its complete extirpation with the knife, but having been separated as far as practicable in the way already men- tioned, it should be well drawn down, and then tied tightly as high as possible with a piece of whipcord, all that portion below the noose being then cut off. In this way the two great dangers that attend the extirpation of tumors in this locality, that are deeply situated and out of sight, viz., hemorrhage and the entry of air into dilated veins, may be avoided, and the ligature being applied beyond the diseased mass, that which remains of it will slough away when the thread separates. During the operation itself all hemorrhage may be controlled by pressure on the subclavian above the clavicle. It occasionally happens that tumors are met with in the axilla as a primary disease, unconnected with any malignant or other morbid action, either in the upper extremity or the breast. Such masses may either be of a strumous or cancerous nature, and require extirpation. When strumous, they are readily enough enucleated; but when cancerous, they become so widely and deeply adherent that their removal cannot be undertaken without much danger. In TAPPING THE CHEST. 765 such dissections as these, I have had occasion to expose the axillary and sub- scapular vessels to some extent. After any bleeding vessels have been ligatured, the incision through which the breast was taken out may be brought together by a few points of suture, and supported by a bandage, so as to prevent bagging of matter. In many cases it will unite by the first intention, for, owing to the yielding nature of the parts in this situation, the lips of the cut come into very good apposition, even though a considerable mass has been removed. By some it has been supposed that relapse of cancer is less liable to take place if the wound unite by granu- lation, than if it come together by more speedy union; of this, however, there is at present no proof with which I am acquainted, though it is by no means improbable that the suppurative action may eliminate cancer-cells from the neighboring tissues. The male breast, though very rarely the seat of disease, may occasionally become affected in a somewhat similar manner to the mammary gland in the female; being in some instances hypertrophied, in others, the seat of an abnor- mal secretion of milk, and, in other cases, affected by the formation of cysts, encysted, and scirrhous tumors. These growths require removal by the same kind of operative procedure that is adopted when they affect the female breast, though of a less extensive character. TAPPING THE CHEST. Paracentesis thoracis may best be done with an ordinary trochar of moderate size, and the most convenient spot for the puncture is usually the side of the chest in the fifth intercostal space, at the line of insertion of the serratus magnus. The skin having been punctured with a scalpel, the trochar should be pushed over the upper margin of the sixth rib into the middle of the space, so as to avoid the intercostal artery, and must then be thrust sharply and boldly Fig. 304. into the pleural sac, so as to make sure of perforating any false membranes that may line its interior, and which, if the instrument he pushed slowly on, might be carried before it, and thus prevent the escape of the fluid. Air may in this operation gain entrance into the pleura, and, decomposing the pus, become a source of irritation. In order to obviate this inconvenience, the instrument figured in the accompanying sketch (fig. 304) will be found useful; the trochar having been introduced, and the stop-cock shut, as the piston-stylet is withdrawn a bladder is attached to the end of the canula, and when this has been filled the stop-cock is again closed, the bladder emptied and reapplied (fig. 305). In this way as much of the fluid as is desired may be removed. After the withdrawal of the canula, the puncture is closed by a pad of lint, strapping, and bandage. After tapping, the lung will either expand, and fill up the cavity previously occupied by the fluid, or if adhesions prevent this, the thoracic parietes will gradually collapse. In hydrops pericardii, the pericardium may be tapped by making an incision 766 HERNIA. Fig. 305. through the skin and cellular tissue in the fifth intercostal space, and then puncturing the membrane with a fine trochar at that point where palpation and auscultation have indicated the greatest amount of fluid. The trochar should be passed obliquely. DISEASES OF THE ABDOMEN. CHAPTER LIII. HERNIA. By hernia, in its widest sense, is meant the displacement of any organ from the cavity in which it is naturally contained, by being protruded through an abnormal or accidental opening in its walls; when, however, it escapes through one of the natural outlets of the part, it is not considered hernial. Thus, the protrusion of the brain through an aperture in the cranium, or of the lung through one in the thoracic walls, or of a portion of intestine through the abdominal parietes, is termed a hernia of these organs; but the descent of the bowel through the anus does not come under this designation. Here, however, we have only to consider the hernial protrusions that occur in the abdomen — the common situation of this disease. A hernia may occur at almost any part of the abdominal wall, though it is far more liable to do so in some situations than in others, being commonly met with at those points where the muscular and tendinous structures are weakened to allow the passage of the spermatic cord in the male, and of the round liga- ment in the female; or for the transmission of the large vessels to the lower extremity; hence the inguinal and crural canals are the common situations of this disease. It may, however, occur in various other situations, as at the um- bilicus, the thyroid foramen, the sciatic notch, in the vagina, the perineum, through the muscular portions of the abdominal wall, the diaphragm, etc. In whatever situation it occurs, a hernia is composed of a sac and its contents. The sac is the prolongation of that portion of the perineum which overlies and corresponds to the aperture through which the hernia protrudes, and is in all CONTENTS OF SAC. 767 cases composed of a neck and body. The neck is usually narrowed, though in some old herniae it becomes wide and expanded: it is commonly short, consfstino- indeed of a sudden constriction of the sac in this situation, as happens in many forms of femoral hernia; but in other cases it is elongated, narrowed, and thick- ened, and even vascular in its structure. The neck of the hernial sac usually becomes greatly thickened, and of an opaque color, in consequence of the depo- sition of plastic matter in or upon it, from the irritation to which it has been subjected by the pressure of the hernial tumor or the truss, from the incorpo- ration of the subserous cellular tissue that lies external to it, or by the pucker- ing together of its folds, which have been compressed by the aperture in which it lies. The body of the sac varies greatly in shape and size, being usually glo- bular or pyriform, sometimes elongated and cylindrical; it may vary from the size of a cherry to a tumor as large as the head. When recent, it is usually thin and transparent, though in some cases it becomes greatly thickened, having arborescent vessels ramifying on it, and being almost laminated in structure; this is especially the case in old femoral herniae. In other instances, however, it becomes thinned and atrophied as the tumor expands, so that the contents become visible through it. This is especially the case in old umbilical herniae, in which I have seen it as thin as the finest gold-beater's skin. In some cases the hernial sac undergoes degeneration, becoming converted into a fibrous or even calcareous layer. The sac, though usually forming a perfect inclosure to the hernial contents, occasionally constitutes but a partial investment to them, more particularly in such organs as the ccecum or bladder, which are naturally partially uncovered by the peritoneum. In other instances, again, it may be ruptured, or altogether absent; more rarely a double hernial sac is met with, one being protruded into or placed behind the other. There are instances of three sacs occurring toge- ther, and Sir A. Cooper even relates a case in which six were met with in the same person. The abdominal parietes outside the sac undergo important changes. The aper- ture through which the hernia protrudes usually becomes circular; after a time, indurated and rounded at the edge, and considerably enlarged; when situated in the movable portions of the abdominal wall, as in the inguinal regions, it becomes displaced in old herniae, being dragged down by the weight of the pro- trusion, usually towards the mesial line. The subserous cellular tissue always becomes greatly thickened, often indurated and fatty, so as to constitute one of the densest investments of the sac, and, in some old cases of hernia, closely to resemble omentum. The more superficial structures, such as the integument and fascia, become much elongated and stretched; often tense, but not unfre- quently hanging in folds; they are usually thinned, but if a truss has been long worn, they become thickened and condensed by the pressure of the pad. The contents of the sac vary greatly, every viscus except the pancreas and stomach having been found in hernial tumors. Most frequently a portion of the small intestine, more particularly of the ileum, is protruded, constituting the form of hernia called enterocele. The quantity of intestine within the sac may vary from a small section of the calibre of the gut, the whole diameter not being included, to a coil several feet in length, with its attached mesentery. After a portion of the intestine has once descended, the protruded part tends to increase in quantity, until, as in some large and old herniae, the greater portion has been known to lie in the sac. The large intestine is rarely found in a her- nia, though the ccecum is occasionally met with. When intestine has been long protruded, it usually becomes thickened in its coats, and narrowed, greyish on the surface, and more or less deranged in its functions. The corresponding mesentery becomes thickened, hypertrophied, and vascular. Omentum is often found in hernial sacs, together with intestine, but is not unfrequently met with alone, constituting the disease called epiplocele. After 768 HERNIA. having been protruded for some time it becomes thickened, brawny, and laminated, losing its ordinary cellulo-adipose texture, and becoming indurated. Its veins usually assume a somewhat varicose condition, and the mass of omentum acquires a triangular shape, the apex being upwards at the abdo- minal aperture, and the base below broad and expanded. In some cases it can be unfolded, in others it is matted together into a cylindrical mass. Occasion- ally apertures form in it, through which a coil of intestine may protrude, thus becoming secondarily strangulated within the sac. In other instances cysts are met with in it containing fluid; or into which the intestine may even slip. When intestine and omentum together are found in a hernia, the disease is termed an entero-epiplocele, and under these circumstances the omentum usually descends before, and occasionally envelops the intestine. Besides these the ordinary contents of herniae, the stomach, liver, spleen, sigmoid flexure of the colon, bladder, uterus, and ovaries, have all been found in them. Adhesions commonly form within the sac in old standing cases. These may take place between the contained viscera merely, as between two coils of intes- tine, or between these and the omentum; or they may form between the wall of the sac and its contents, either by broad bands, or else by bridging across from one side to the other, and enclosing a portion of the viscera. In recent cases these adhesions are soft, and may readily be broken down; but when of longer duration they are often very dense, and are especially firm about the neck of the sac. Besides the viscera, the hernial sac always contains a certain quantity of fluid secreted by and lubricating its interior. In most cases this is in but small quantity, but in some instances, when the sac is in- Fig. 306. flamed, or the hernia strangulated, a very considerable bulk of liquid has been met with; I have seen as much as a pint escape from a large hernia in an old man. When abundant, it is generally of a brownish color, though clear and transparent, and is met with in largest quantities in inguinal herniae. In some in- stances this fluid becomes collected in a kind of cyst within the sac formed by the omentum contracting adhesions to its upper part, and leaving space below for the fluid to collect, in which this accumulates be- tween the omentum above and the wall of the sac below; this condition, represented in the annexed figure (306), has been called hydrocele of the hernial sac, and constitutes a somewhat rare form of disease. The fluid is often in considerable quantity; in a case which I tapped some years ago, nearly three pints of dark brown liquid had thus accumulated, and were drawn off. If we limit the term hydrocele of the hernial sac to those cases in which there is a slow and gradual accumulation of fluid at the bottom of an old hernial sac, which has been cut off from all communication with the peritoneum either by the radical cure of the hernia, or by the adhesion of intestine or omentum to the upper part and neck of the sac, it must be considered a disease of unfrequent occurrence, and but few cases are recorded by surgical writers. Mr. Curling, in his work on the Testis, states that during his connection with the London Hos- pital, he has seen only one case; and the only others with which I am acquainted, besides one that occurred in my own practice, are two related by Pott, two by Pelletan, one by Boyer, and one by Lawrence. This disease must not be con- founded with the accumulation of fluid, in whatever quantity, in strangulated hernia, or in hernial sacs that communicate with the peritoneal cavity. Its distinguishing feature is the accumulation of fluid in a sac that has been cut off from all communication with the cavity of the peritoneum. CAUSES OF HERNIA. 769 The symptoms of hernia, though varying considerably according to the con- tents of the sac and the condition in which it is placed, present in all cases many points in common. Thus there is an elongated or rounded tumor at one of the usual abdominal apertures, broader below than above, where it is often narrowed into a kind of neck; usually increasing in size if the patient stands, holds his breath, coughs, or makes much muscular exertion. It can be pushed back into the abdomen on pressure, or goes back readily if the patient lies down, but reappears when he stands up. On coughing, a strong and distinct impulse may be felt in it. When the hernia is altogether intestinal, it is usually smooth, gurgling when pressed upon, and sometimes tympanitic and rumbling. It may be returned into the cavity of the abdomen with a distinct slip and gurgle; it has a well-marked impulse on coughing, and is usually accompanied by various dyspeptic symptoms, and often with a good deal of dragging uneasiness. The omental hernia is usually soft and doughy, returning slowly on pressure into the abdomen, feeling irregular on the surface, and having an ill-defined outline. It occurs most frequently on the left side, and is rare in infants, in whom the omentum is short. In entero-epiplocele there is a combination of the two conditions and their signs; but these are usually so uncertain, that few surgeons care to predict before opening the sac what the probable nature of the contents may be. Cecal hernia necessarily only occurs on the right side. It is a large, knobby, and irregular tumor, irreducible, owing to the adhesions contracted by that portion of ccecum which is uncovered by peritoneum. The peculiarity of these hernise consists in the sac being absent, or only partial in the majority of cases, owin°- to the peritoneum stripping off as the gut descends. When these herniae are Large, and partially invested by serous membrane, a sac usually exists at their upper aspect, into which a portion of small intestine may fall, and which may in some cases constitute a second hernia lying above or before the coecal one, which will be found situated at the posterior wall when this hernial pouch is opened. Occasionally the vermiform appendix and the caput-coli are found in the sac, but can rarely be returned. The rule of ccecal herniae only having a partial peritoneal investment, does not hold good in all cases; and instances have occasionally been met in which this portion of intestine lay in a distinct sac. Hernia of the bladder or cystocele is of very rare occurrence; and, like that of the ccecum, is usually enclosed in a partial peritoneal investment, though it is not necessarily so. South states that there is a preparation at St. Thomas's Hospital, in which the fundus of the bladder, with its peritoneal covering, has passed into a distinct sac. In some instances the cystocele is accompanied by an enterocele. These herniae are always irreducible, and are attended by a good deal of difficulty in urinating, with varying tension, according to the quantity of fluid they contain; by squeezing them, urine may be forced out through the urethra, and fluctuation has been felt in them. Urinary calculi have been formed in these tumors, and have been removed by incision through the scrotum, or have ulcerated out. The causes of hernia are usually sufficiently well marked. In some instances, the disease is congenital, arising from preternatural patency of the abdominal apertures; in other cases, again, it occurs at a later period of life, in consequence of some forcible effort, as in lifting a heavy weight, jumping, coughing, strain- ing at stool, or in passing water through a tight stricture. It is especially apt to occur from such causes as these in tall and delicate people, more particularly in those who have got a natural disposition to weakness, or bulging of the groins The displacement of the abdominal viscera by a gravid uterus, will also occasionally give rise to the disease. Hernia is especially apt to occur from a combination of causes: thus, if an aged person, one with a feeble organization, 49 770 HERNIA. or whose abdominal apertures have been patent in consequence of rather sudden emaciation, makes a violent effort, a hernial protrusion is very apt to occur. Amongst the most frequent predisposing causes of hernia are certainly sex, age, and occupation. Men are far more liable to this disease than women. Thus, according to Malgaigne, in France one man in thirteen and one woman in fifty-two, are the subjects of hernia. But, though men are more generally liable to hernia than women, they are less so to certain forms of the disease, especially to the femoral and umbilical. It is to the inguinal that they are par- ticularly subject, although old women very commonly suffer from this form. According to Mr. Lawrence, out of 83,584 patients who applied to the City of London Truss Society, 67,798 were males, and 15,786 females; for the inte- resting statistical account of the relative frequency of the different kinds of rup- ture, deduced from the foregoing figures, I would refer to Mr. Lawrence's most excellent Treatise on Hernia, 5th ed. p. 11. Age exercises a very material influence upon the frequency of hernia. Malgaigne, who has carefully investigated this subject, finds that in infancy the disease is sufficiently common, owing to the prevalence of congenital hernia at this period of life; and, that in the first year after birth hernia occurs in the proportion of 1 in every 21 children. It then goes on decreasing in frequency, there being 1 in 29 at the second year; 1 in 37 at the third year; until, at the thirteenth year, it has fallen to 1 in 77. Shortly after this, its frequency begins to rise again, and then goes on progressively increasing until the close of life; thus, at the 21st year, there is one case in 32; at the 28th year, 1 in 21; at the 35th, 1 in 17; at the 40th, 1 in 9; at 50, 1 in 6; from 60 to 70,1 in 4; and from 70 to 75,1 in 3. In women, hernia most frequently occurs from the 20th to the 50th years. Those occupations in which the individual is ex- posed to violent muscular efforts, more particularly of an intermitting character, predispose strongly to the occurrence of hernia, and in these employments the tendency to the disease is often greatly increased by the injurious habit of wearing tight girths or belts round the waist, which, by constricting the abdo- men, throw the whole pressure of the abdominal contents upon the inguinal regions. The conditions in which a hernia may be found, are very various, and entail corresponding differences in the result and treatment of the affection. When first formed, most herniae may be said to be incomplete, being for a time retained within the orifice of the canal through which they eventually protrude; when they have got altogether beyond the abdominal walls, they are said to be complete, and this is the condition in which they are usually presented to the surgeon. A hernia is commonly at first reducible, that is to say, it may readily be pushed back into the cavity of the abdomen, protruding again when the patient stands up, holds his breath, or makes any exertion, and having a distinct and forcible impulse on coughing. Though the hernial contents, in these cases, are reduced into the abdomen, the sac is not; it almost immediately contracts adhesions to the cellular tissue, by which it is firmly fixed in its new situation, though in some particular cases, as we shall hereafter see, it may be pushed back. In the treatment of a reducible hernia, our object is by the application of a proper truss, to retain the protrusion within the cavity of the abdomen. In order to do this, the patient must be provided with a proper kind of truss, adapted to the particular nature of the hernia. Amongst the best are, I think, Salmon and Odys', or Tod's, for inguinal hernia, and the Mocmain for the femoral. In umbilical and ventral ruptures, an elastic pad and belt may most conveniently be used. In selecting these trusses, care should be taken that the spring is of proper strength, adapted to the size and power of the individual, and that it be properly shaped, so that it does not touch any part of the abdo- minal wall, but merely bears upon the points of pressure and counter-pressure. RADICAL CURE OF HERNIA. 771 The pad should be convex, and firmly stuffed, and of sufficient size to press not only upon the external aperture, but upon the whole length of the canal. Be- fore applying the truss, the hernia must be reduced, by placing the patient in the recumbent position, relaxing the muscles by bending the thigh upon the abdomen, and pressing the tumor back in the proper direction; the truss should then be put on, and be worn during the whole of the day; indeed, the patient should never be allowed to stand without wearing it. At night, it may either be left off altogether, or a lighter one applied. In some cases the skin becomes irritated by the pressure of the pad; under these circumstances, an elastic air- cushion may be used, or the parts subjected to pressure may be well washed with spirit lotion. The truss may be known to fit by testing it in the following way. The patient should be made to sit down on the edge of a chair, and then extending his legs, opening them widely, and bending the body forwards, cough several times. If the hernia do not slip down behind the pad on this trial, we may be sure that the truss is an efficient one, and will keep the rupture up under all ordinary circumstances. Radical cure of Hernia.—Various means have been devised in order to effect the radical cure of a reducible hernia. The only plan that is at the same time perfectly safe and permanently successful is by the compression of a well-made truss. In this way it not unfrequently happens that the hernias of infants be- come radically cured; the same result however seldom occurs at a more advanced period of life. In order that compression should succeed in this way, it is necessary that it should not only be applied to the external aperture through which the rupture escapes, but to the whole of the canal. It must also be con- tinued for a very considerable time, for at least a year or two, and care should be taken that during the treatment the rupture is not allowed to descend; every time it comes down, any good that may have been derived is necessarily done away with, and the treatment has to begin, as it were, anew. After the cure is supposed to have been effected in this way, the application of the truss must be continued for a very considerable length of time, lest by any unfortunate move- ment the rupture descend again. The operations that have been devised for the radical cure of hernia are all founded on one of two principles, viz., the excitation of such an amount of peritonitis in the sac, or its neck, as to secure its obliteration, or the plugging of the hernial aperture by invagination of the integumental tissues. If the accomplishment of these conditions would always prevent the recur- rence of the rupture, the radical cure might frequently be undertaken. But it is impossible to look upon the agglutination of the walls of the sac, or the closure of the abdominal aperture, as the sole conditions required. To accom- plish the radical cure, it would be necessary in many cases to effect changes in the shape and connections of the abdominal contents, to alter the size of the abdominal cavity, and indeed to modify in various ways many conditions inde- pendently of those immediately connected with the hernial protrusion. Many of the means of radical cure, by which obliteration of the interior of the sac or its neck is sought to be effected by the application of sutures or ligatures, the introduction of caustics, its excision, scarification, puncture, or injection with tincture of iodine, are attended with so much danger from peritonitis, and so seldom by any good results, that their consideration need not detain us here. The same remark applies to the attempt to obliterate the canal through which the hernia protrudes, by invaginating and stitching into it a portion of the neighboring integument, which operation, though much cried up, especially by some of the continental surgeons, who have extensively practised it, has been found very seldom to be attended by any permanently beneficial results; the invaginated portion of tissue speedily yielding to the outward pressure of the viscera, allowing recurrence of the hernia to take place. Of late years, how- ever, Wiitzer, of Bonn, has adopted a plan of radically curing reducible inguinal 772 HERNIA. herniae, which combines the two principles on which the older operations were founded, viz., the agglutination of the neck of the hernial sac by the exci- tation of inflammation in it, and the closure of the inguinal canal by the inva- gination of the scrotum; and he carries out these objects in a safer and more successful manner than by any of the methods previously employed. This plan of treatment consists in introducing a plug of the scrotum into the inguinal canal, and fixing it there by exciting adhesive inflammation in the neck of the sac. The details of the operation are as follow: The patient lying on his back, and the hernia being reduced, the surgeon pushes his index-finger up the in- guinal canal as high as the internal ring, carrying before it a cone of the scrotal tissues; a box-wood hollow cylinder, about four inches long (fig. 307 C), well Fig. 307. /A B G c oiled, is then pushed up as the finger is withdrawn, so as to occupy its place in the inguinal canal. Along the interior of this cylinder a flexible gilt-steel needle (A), fixed in a movable handle, is then pushed, so as to traverse the inva- ginated scrotum, the hernial sac, and the anterior abdominal wall, through which its point is caused to protrude. A concave box-wood case (B) is then passed over the projecting point of the needle, and fixed by the other end by a screw apparatus to the cylinder (C), so as to compress the inclosed tissues. The apparatus so fixed is left in situ for six or eight days, when some discharge being established, it is withdrawn, and the invaginated scrotal plug supported by lint introduced up its interior, and by a spica bandage. The patient is kept quiet for a fortnight longer, when he is allowed to move about, wearing a light truss for three or four months. This method of treatment is easy of execution, and appears to be more suc- cessful than any that has preceded it. And yet it is open to the objections that attend all plans for the radical cure of hernia, viz., the possible excitation of a dangerous amount of peritonitis, and the want of adhesion between the lower part of the scrotal plug and the corresponding part of the inguinal canal and ring. It should of course not be employed indiscriminately, but only in those cases in which, from the laborious nature of the employment and the otherwise good health of the patient, the radical cure may fairly be attempted. Irreducible herniae are usually of old date, and large size. They generally contain a considerable quantity of thickened omentum, as well as intestine and mesentery. In many instances, a rupture of this kind is partly reducible, the greater portion remaining behind. It is usually the gut which slips up, and the omentum that cannot be returned. The irreducibility of a rupture may either be owing to its shape, to the existencejof adhesions, or be dependent on its very nature. If the sac become the seat of an hour-glass contraction, ot its neck become elongated and narrowed, the hernial contents may continue permanently protruding. So also the expanded condition of the lower part of the omentum, and the narrowing of its neck may prevent a return of the rup- ture. The existence of adhesions, either between the sac and its contents, or between protruded intestine and omentum, will commonly render a hernia irre- ducible; and most frequently these are associated with changes in the shape INFLAMED AND INCARCERATED IRREDUCIBLE HERNIA. 773 of the sac or the omentum. Herniae of the ccecum and bladder can never be returned, on account of the anatomical conditions, to which reference has already been made. An irreducible hernia is usually a source of great inconvenience; it has a tendency to increase if left to itself, until at last it may contain, as in some ex- treme cases it has been found to do, the greater portion of the abdominal viscera, forming an enormous tumor, inconvenient by its size and weight, in which the penis and scrotum are buried. Even when the irreducible hernia is of small size, it gives rise to a sensation of weakness in the part, with dragging pains, and is very frequently accompanied by colicky sensations and dyspeptic derange- ments. The patient also, under these circumstances, is in a state of considerable danger, lest the rupture becomes strangulated by violent efforts, or injured and inflamed by blows. For these reasons, it is necessary not only to protect a rupture of this kind from external violence, but to endeavor to prevent its increase in size. This may best be done by letting the patient wear a truss with a large concave pad, which supports and protects it provided the rupture be not of too great a size for the application of such an instrument. If its magnitude be very considerable, it must be supported by means of a suspensory bandage. Mr. Bransby Cooper has recommended that an attempt should be made to convert the irreducible into a reducible hernia, by keeping the patient in bed for several weeks, on low diet,, with the continued application of ice to the tumor; and if it contain much omentum, giving small doses of blue pill and tartar emetic, so as to promote the absorption of the fat. This plan, which appears to have answered well in some cases, certainly deserves a further trial. The occurrence of inflammation in an irreducible hernia is a serious compli- cation, and one that simulates strangulation very closely. When this complica- tion occurs the part becomes swollen, hot, tender, and painful; there is not much tension in the tumor which is seldom increased beyond its usual magnitude; there is a good deal of pyrexia, and symptoms of peritonitis spreading from the vicinity of the inflamed rupture set in. In some cases there is vomiting, but it is not constant, and never feculent, occurring generally early in the disease, and consisting principally of the contents of the stomach, being apparently an effort of nature to get rid of an indigestible meal. If there is constipation, as usually happens in all cases of peritonitis, it is not complete, flatus occasionally passing per anum, together with a small quantity of fluid faeces. It is of importance in these cases to observe that the inflammation commences in the body of the sac, and extends into those parts of the abdomen that are contiguous to its neck; the stomach and intestinal derangements being secondary to this condition. The treatment of an irreducible hernia must be directed to the peritonitis which attends it; the application of leeches to the sac and its neck, the free administration of calomel and opium, the employment of enemata, with strict antiphlogistic regimen and rest, will usually speedily subdue all inflammatory action. An irreducible hernia occasionally becomes obstructed, then constituting the condition termed incarcerated hernia. This condition principally occurs in old people, by the accumulation of flatus, or of undigested matters, such as cherry stones or mustard seeds, in an angle of the gut. In these cases there is con- stipation, with eructation, and perhaps occasional vomiting. There may be some degree of pain, weight, or uneasiness about the tumor, but there is no tension in it or its neck, and the symptoms altogether are of a chronic and subacute character. The treatment of such a case as this should consist in the administration of a good purgative injection; the compound colocynth enema is the best, thrown up as high as possible by means of a long tube. Ice may then be applied to the tumor for about half an hour, and then the taxis, as will immediately be described, may be used under chloroform. The ice may be omitted in those cases in which, on handling the tumor, gurgling can readily 774 STRANGULATED HERNIA. be felt; but the taxis should always be used, as by it the incarcerated gut may be partially emptied of its contents; or if any additional protrusion should have happened to have slipped down, this maybe returned. After these means have been employed, an active purgative, either of calomel or croton oil and colo- cynth should be administered, and if any inflammation ensue, this must be treated as already described. STRANGULATED HERNIA. A hernia is said to be strangulated when a portion of gut or omentum that is protruded is so tightly constricted that it cannot be returned into the abdo- men ; having its functions arrested, and if not relieved speedily, running into gangrene. This condition may occur at all periods of life, being met with in infants a few days old, and in centenarians. It commonly arises from a sudden violent effort by which a fresh portion of intestine is forcibly protruded into a previously existing hernia, which it distends to such a degree as to produce this strangulation. But though old herniae are more subject to this condition than recent ones, it may occur at the very first formation of a hernial swelling, the gut becoming strangled as it is protruded. There are, therefore, two dis- tinct kinds of strangulation. One which may be said to be of a passive kind, chiefly occurring in elderly people, the subjects of old and perhaps irreducible hernias, which in consequence of some accidental circumstance become distended by the descent of a larger portion of intestine than usual, and this, undergoing constriction and compression at the neck of the sac, gradually becomes strangu- lated. The other kind of strangulation is most frequent in younger individuals; in it the symptoms are of a more active character, the bowel becoming pro- truded in consequence of violent exertion, and undergoing rapid strangulation, the tension of the parts not having been lessened by the previous long exist- ence of an irreducible hernia. The mechanism of strangulation has been attributed either to a spasmodic action of the walls of the aperture through which the hernia protrudes, or else may be considered as dependent on changes taking place in the protruded parts, subsequent to and occasioned by their constriction by the tissues exter- nal to them. The strangulation cannot, I think, with justice, ever be regarded as of a spasmodic character, the aperture in the abdominal wall, through which the hernia escapes, being tendinous, or fibrous, and certainly not in any way contractile, though the action of the abdominal muscles may undoubtedly in- crease the tension of its sides; the continued and permanent character of this strangulation, when once it has taken place, would also discountenance this opinion ; those forms of hernia, indeed, as the ventral, which occur in purely muscular structures, being very rarely strangulated, and when they are so, the constriction being generally occasioned by the formation of dense adventitious bands upon or within the sac, and not by any muscular agency. Strangulation certainly appears in all cases to be the result of congestion of the protruded parts, induced by the constriction to which they are subjected; the mechanism being as follows: — A knuckle of intestine, or bit of omentum is suddenly protruded during an effort of some kind. This immediately be- comes compressed by the sides of the narrow aperture through which it has escaped; the return of its venous blood is consequently interfered with, and swelling and oedema rapidly ensue, together with stagnation of the blood in it. If the constriction be excessively tight, the walls of the ring being very hard and sharp, the part that is so strangulated maybe deprived of its vitality in the course of a few hours. If the strangulation be less severe, the congestion will run into inflammation, the changes characteristic of this condition speedily supervening. In proportion as the congestion augments, and the inflammation STRANGULATION. — SEAT OF STRICTURE. 775 comes on, the return of the protruded parts is necessarily rendered more diffi- cult by the increase of their swelling. The stricture is most commonly situated outside the neck of the sac in the tendinous or ligamentous structures surround- ing it; not unfrequently in the altered and Fig. 308. thickened subserous cellular tissue. In other cases again, and indeed with great frequency, it is met with in the neck of the sac itself (fig. 308), which is narrowed, elongated, and tubular, or constricted by bands that are incorporated with it. More rarely it exists in the body of the sac, which may have assumed an hour-glass shape. In some cases it would appear as if this particular shape were owing to an old hernia having been pushed down by a recent one above it. The stricture is sometimes, though by no means frequently met with inside the sac, con- sisting of bands of adhesions stretching across this, or of the indurated edge of an aperture of the omentum through which a portion of the gut has slipped. The changes induced in the strangulated parts result from the pressure of the stricture and the consequent interference with the circulation through them. If the strangulation is acute, that portion of intestine which lies immediately under the stricture will be seen to be nipped or marked by a deep sulcus, which is occasioned partly by the pressure to which it has been subjected, and partly by the swelling up of the congested tissues beyond it. The changes that take place in the protruded intestine rapidly increase in proportion to the length of the continuance of the strangulation. The tightness of the stricture and the acuteness of the strangulation have, however, more to do with these changes than even the time that it has lasted. I have seen the bowel so tightly nipped that, though the strangulation had only existed eight hours when the ope- ration was performed, the vitality was lost in the part constricted (fig. 307); and in other cases I have known the strangulation to have lasted for five or six days before the operation was performed, and yet the part recover itself. The first change that takes place in the protruded parts in a case of strangu- lated hernia is their congestion; this rapidly ruus on to inflammation, and speedily terminates in gangrene. The protruded bowel becomes, at first, of a claret, maroon, or purplish-brown color, sometimes ecchymosed on the surface, with thickening and stiffening of its coats, owing to effusion into their sub- stance ; some liquid is also usually poured out into its interior. In this stage, that of congestion, the omentum will also be found with its veins a good deal congested. When inflammation has set in, the bowel preserves the same color as in the congested condition, but usually becomes coated here and there with flakes of lymph, which give it a rough and villous look; the omentum has a somewhat rosy tinge, and there is usually a good deal of reddish fluid poured out into the sac. When gangrene occurs, the bowel loses its lustre and polish, becoming of an ashy grey, or dull black color, soft and somewhat lacerable, so that its coats readily separate from one another; the serous membrane espe- cially peeling off. The omentum is dark purplish, or of a kind of dull yellowish- grey, and there is usually a considerable quantity of dark, turbid serum m the sac, the whole contents of which are extremely offensive. Most usually when gangrene occurs in a strangulated rupture, inflammation of the sac and its coverings takes place, accompanied, after a time, by a reddish-blue or congested appearance and some tenderness on pressure, and if the part is left unreduced, eventually emphysematous crackling. If the case is left without being relieved, 776 STRANGULATED HERNIA. gangrene of the skin will at last take place, the sac giving way and the fa?cal matters being discharged through the softened and disintegrated tissues. Under such circumstances as these, which, however, are very rarely met with at the present day, the patient usually eventually dies of low peritonitis by extension of the inflammation to the serous membrane. No effusion, however, of feculent matter will take place into the peritoneal cavity even under such unfavorable conditions; the portion of bowel immediately within the stricture becoming adherent by plastic matter to this on its internal surface, and thus the escape of any extravasation into the cavity of the abdomen being prevented. It does not always follow that there is any external evidence of the occurrence of gangrene within the sac; and the bowel is frequently nipped to such an extent as to pre- vent its regaining its vitality without any unusual condition being presented until the sac is actually laid open and the intestine examined. In the more advanced cases of strangulated hernia, the peritoneum always becomes inflamed, usually to a considerable extent, the disease affecting a diffuse form, accompanied by the effusion of turbid serum, often of a very acrid and irritating character, and mixed with flakes of lymph, sometimes to such an extent as to give it a truly puriform appearance. This glutinous lymph mats together contiguous coils of intestine, often appearing to be smeared over them like so much melted butter. The symptoms of strangulation are of two kinds: 1st, as they affect the tumor; and 2d, as they influence the constitution generally. 1st. The tumor, if the hernia be an old one, will be found increased in size, or it may appear for the first time when strangulated. It will generally be found to be hard, tense, and rounded, more particularly if it be an entrocele. When the hernia is in a great measure omental, it is, however, not unfre- quently soft and doughy, though strangulated. It seldom increases in size after strangulation has occurred, as no fresh protrusion can take place below the stricture, but I have known it to be greatly augmented in bulk after the strangulation had existed for some hours, by the effusion of serum into the sac. If the hernia have previously been reducible, it can no longer be put back, and there is no impulse in it, or increase in its size on coughing, the stricture pre- venting the transmission of the shock to the contents of the tumor; and in this way, as pointed out by Mr. Luke, the situation of the constriction may sometimes be ascertained by observing at what point the impulse ceases. 2d. So soon as the strangulation has occurred, the patient becomes uneasy and restless. If the constriction be of an active character, he will be seized with acute pain in the part, which speedily extends to the contiguous portion of the abdomen, assuming the characters of peritoneal inflammation. The first thing that happens when intestine is strangulated, whether a large coil be con- stricted, or a small portion only of the diameter of the gut be nipped, is an arrest of the peristaltic movement of the part implicated, the occurrence of obstruction to the onward course of the intestinal contents, followed by consti- pation, vomiting, and colicky pains. The constipation is always complete, nei- ther feces nor flatus passing through; the bowels may sometimes act once after the strangulation has occurred from that portion which lies below the seat of constriction, but they cannot, of course, empty themselves thoroughly, or from above the strangled part. Vomiting usually sets in early, and is often of a very severe and continuous character, with much retching and straining; at first con- sisting of the contents of the stomach, with some bilious matters, but afterwards becoming feculent, or stercoraceous, owing to inverted peristaltic action extend- ing as far down as the constricted part of the gut. These symptoms are attended by colicky and dragging pains about the navel. They are more severe in their character when the strangulation is acute and the hernia is intestinal, than when it is passive, and the rupture omental. They occur equally in the incomplete as in the complete forms of the disease; indeed, it not unfrequently happens DIAGNOSIS OF STRANGULATED HERNIA. 777 that the hernial tumor may be so small as to have escaped observation; the occurrence of the above symptoms being the first indication of the probable nature of the mischief. Hence, it is well always to examine for hernia when called to a patient suddenly seized with constipation, vomiting, and colicky pains, even if told that no tumor exists. After the strangulation has existed for some time, the inflammation that occurs in the sac extends to the contiguous peritoneum, accompanied by the ordinary signs of peritonitis, such as tension of the abdominal muscles, tender- ness, with lancinating pains about the abdomen, and tympanitis. The patient lies on his back with the knees drawn up, has a small, hard, quick, and perhaps intermittent pulse, a dry tongue, which speedily becomes brown, and a pale, anxious, and dragged countenance, with a good deal of heat of skin, and inflammatory fever. In some cases, this is of a sthenic type, but, in the majority of instances, especially in feeble subjects, it assumes the irritative form. When gangrene of the rupture takes place, hiccup usually comes on, with sudden cessation of pain in the tumor, an intermittent pulse, cold sweats, pallor, anxiety, rapid sinking of the vital powers, usually with slight delirium, and speedy death. The symptoms just given are those that we usually meet with in strangulated hernia. They may, however, be modified in some important respects. 1st. There may be little or no tension in a strangulated hernia, the tumor continuing soft and lax; this is especially the case when the hernia contains omentum, and in congenital herniae when strangulated. It may also occur in the case of double herniae on the same side, in consequence of the outer sac being empty, or merely filled with serum, and the posterior one being protruded against this and strangulated; but its tension being masked by the lax state of the outer one. 2d. Vomiting sometimes does not take place from first to last, there being at most a little retching; at other times the patient vomits once or twice, and then there is no recurrence of this symptom so long as he remains quiet. 3d. Extensive peritonitis with copious effusion of a puriform liquid may occur without any pain, and with but little tenderness; the anxiety of counte- nance and sharpness of pulse being the only symptoms that lead to a suspicion of its existence. 4th. Death may result from exhaustion consequent on vomiting and peri- tonitis, without any sign of gangrene in the constricted portion of intestine. Strangulated hernia requires to be diagnosed — 1st. From an obstructed irreducible hernia. In this there are no acute symptoms, and the rupture will generally be found to be a large one of old standing. It may become somewhat tense and swollen, but is not tender to the touch, and always presents a certain degree of impulse on coughing. There is no sign of peritonitis. There may be constipation, but there is no vomiting, or if there be any, it is simply of a mucous and bilious character, consisting of the contents of the stomach. The speedy restoration of the intestinal action, by the treatment already indicated as proper in these cases, will remove any doubt as to the nature of the affection. 2d. From an inflamed irreducible hernia. Here there is great tenderness and pain in the tumor, with pyrexia, and some general peritonitis, but there is no vomiting; or if the patient have vomited once or twice, he does not continue to do so with that degree of violence, or in the same quantity, as he would if the peritonitis were the result of strangulation. Then, again, the constipation is not absolute and entire, but flatus and liquid faeces will usually pass. _ ^ 3d. From general peritonitis conjoined with hernia, the diagnosis is often extremely difficult, more especially if the hernia be an irreducible one. In these cases, however, it will be observed that the peritonitis may be most intense at a distance from the sac; that there will be little or no vomiting, or if there 778 STRANGULATED HERNIA. be, that it is simply of mucus, and the contents of the stomach; and that the constipation is by no means obstinate or insurmountable by ordinary means. 4th. In the case of double hernia, one tumor may be strangulated and the other not, though irreducible. Under these circumstances it may at first be a little difficult to determine which one is the seat of constriction. This, how- ever, may be ascertained, as in a case that was lately under my care at the Hospital, by observing greater tension and tenderness about the neck of the strangulated, than of the unconstricted one. Besides these various conditions of hernia, which may be confounded with strangulation, there are other tumors which may likewise be mistaken for this disease, but these we shall have to consider when speaking of the special forms of hernia. The treatment of strangulated hernia, is one of the most important subjects in surgery The object sought to be accomplished is the removal of the con- striction from the strangled hernial tumor. This is effected either by the reduction of its contents or the division of the stricture. The reduction of the hernia is effected by the employment of the taxis, by which is meant the various manual procedures employed in putting the rupture back. The taxis, when properly performed, is seldom attended by any serious consequences to the patient. I have never known it followed by death, and out of 293 cases of hernia reported by Mr. Luke, as having been reduced by the taxis in the London Hospital, none died. It is not unfrequently followed, however, by rather a sharp attack of peritonitis, which might probably, in some instances, prove fatal; in one instance I have seen it followed by very abundant hemor- rhage from the bowel, probably owing to the rupture of some of the congested vessels of the strangled portion of the gut. In using the taxis, great care should in all cases be employed, and no undue force should ever be had recourse to. No good can ever be effected by violence, the resistance of the ring cannot be overcome by forcible pressure, and a vast deal of harm may be done by squeezing the tender and inflamed gut up against its edge, causing it to overlap, and thus to be bruised or even perhaps torn. The taxis should not be pro- longed beyond half an hour; if properly employed for this time, the hernia, if reducible, will probably go back. If it be employed, as it is often very impro- perly, for a lengthened period, and by several surgeons in succession, the pro- truded part becomes ecchymosed, irritated, and disposed to inflammation, and the chances of recovery after a subsequent operation are much lessened. When the parts are much inflamed, the taxis should be employed with great caution; and if it have been fairly and fully used by another surgeon it is better not to repeat it. When gangrene has occured, it should never be employed, as the putting back of the mortified gut into the abdomen would be followed by extravasation of faeces and fatal peritonitis. In using the taxis, it should be borne in mind that there are two obstacles to overcome; the resistance of the parts around the ring, and the bulk of the tumor. The first may be somewhat lessened by relaxing the abdominal muscles, and consequently diminishing the tension exercised upon the tendinous apertures and fasciae of the groin. In order to effect this, the patient should be placed in a proper position, the body being bent forwards, the thigh adducted, and semi-flexed upon the abdomen; the surgeon may then, by employing steady pressure on the tumor, endeavor to squeeze out some of the flatus from the strangled portion of intestine, and thus to effect its reduction. In doing this, the neck of the sac should be steadied by the fingers of the left hand; whilst, with the right spread over the tumor, the surgeon endeavors to push it backwards, using a kind of kneading motion, and sometimes in the first instance drawing it slightly downwards, so as to disentangle it from the neck of the sac. The direction of the pressure is important; it should always be in the line of the descent of the tumor. These means may be employed as soon as the patient is seen by the surgeon, when, by steadily carrying on the taxis for a few THE TAXIS IN STRANGULATED HERNIA. 779 minutes, he will perhaps hear and feel a gurgling in the tumor, which will be followed by its immediate reduction. If the patient is thin, and the outline of the aperture through which the hernia escapes, tolerably defined, I have suc- ceeded in reducing the protrusion, after failure of the taxis in the ordinary way, by passing the tip of my finger or the nail under the edge of the ring, and pulling this firmly and forcibly on one side so as to steady and at the same time dilate it, pressure being kept up on the tumor with the other hand. This manoeuvre can be practised with more facility and success in femoral hernia, where the upper edge of the saphenous opening is sharply defined, but may also successfully be had recourse to in inguinal and umbilical protrusions; should, however, reduction not ensue, it will be desirable to have recourse at once to further means, the object of which is by relaxing the muscles and lessening the bulk of the tumor to enable the hernia to be reduced. The means to be employed must be modified according to the condition of the strangulation, whether it be of the active or passive kind. If it be very acute, occurring in a young, robust, and otherwise healthy subject, the patient may have about twelve or sixteen ounces of blood taken away from the arm; he should then be put into a hot bath, where he may remain for twenty minutes or half an hour, or until he feels faint, and whilst in the bath in this condition the taxis should be employed. If it do not succeed, he should be taken out, wrapped up in blankets, and have chloroform administered. When fully under the influence of this agent, which is certainly the most efficient that we possess for relaxing muscular contraction, the taxis may be tried once again. Should it still fail, the operation should be immediately proceeded with. No good can possibly come of delay in these cases, and repeated attempts at the taxis should be carefully avoided. If the hernia does not admit of reduc- tion in the early stage of the strangulation, it will necessarily be much less likely to do so when tbe parts, by being squeezed and bruised by much manipu- lation, will have their congestive condition greatly increased. The frequent employment of the operation without opening the sac, of late years, very pro- perly renders surgeons much less averse to early division of the stricture than was formerly the case. When the strangulation is less acute, or occurs in a more aged or less robust subject, it is well to omit the bleeding, and to trust to the warm-bath and the chloroform. When the strangulation is of a passive character, and occurs in feeble or elderly people, other measures may be adopted with the view of lessening the bulk of the tumor, which, rather than the tension of the parts, offers the chief obstacle to reduction in these cases. Under such circumstances, especially when the tumor is large, and not very tense, I think it is well to dispense with the hot-bath, which has sometimes a tendency to increase any congestion that may already exist in the hernia; I have in more than one case seen a strangulated rupture enlarge considerably after the employment of the bath. In such cases as these, more time may safely be spent in attempts at reduction than in very acutely strangulated herniae. It is, I think, a useful practice to commence the treatment by the administration of a large enema, which, by emptying the lower bowel, will alter the relations of the abdominal contents, and may materially facilitate the reduction of the tumor. The best enema is one of gruel and cas- tor-oil, with some spirits of turpentine added to it; it should be injected through a full-sized tube, and passed high up into the gut, and with a moderate degree of force. In administering it, care must be taken that no injury be done to the bowel. It would scarcely be necessary to give such a caution as this, were it not that I was summoned, some years ago, by two very excellent practitioners to see a woman with strangulated femoral hernia, to whom an enema of about two quarts of tepid water had been administered; and as this had not returned, and did not appear to have gone up the bowel, they suspected that it must have 780 STRANGULATED HERNIA. passed out of the rectum into the surrounding cellular tissue. As the patient, however, did not seem to be suffering from this cause, and as the symptoms of strangulation were urgent, I operated on the hernia. Death suddenly occurred, apparently from exhaustion, in about eight hours, and on examining the body it was found that the rectum had been perforated, the fluid injected into the meso-rectum, separating the gut from the sacrum, and had thence extended into the general sub-peritoneal cellular tissue, which contained a quantity of the liquid; some of the water also appeared to have got into the peritoneal cavity. In the large herniae of old people in which there is a good deal of flatus, after the enema has been administered, a bladder of ice may be applied for three or four hours with excellent effect. Chloroform may then be given, and the taxis employed under its influence. Of late years, indeed, I have been in most cases in the habit of trusting almost solely to chloroform as a relaxing agent, and have often dispensed with-the use of the warm-bath, and the other means just detailed. I put a patient with strangulated hernia at once under chloroform, and then try the taxis for a few minutes, not exceeding half an hour; if this fail, I then at once proceed to the operation without any further attempts at reduction, which are not only useless, but injurious, by bruising the protruded parts. After the reduction of a strangulated hernia, constipation and retching, with nausea, may occasionally continue; and the tumor, if the hernia have been small and deep-seated (more particularly if femoral), may continue to be felt, though less tense than before; consisting simply of the sac thickened and in- flamed, with serous fluid in it. Under these circumstances we must be careful not to operate. I have, on two or three occasions, seen an empty sac operated on, to the annoyance of the surgeon and danger of the patient. The mistake may be avoided by observing that the symptoms gradually lessen in severity by waiting, and that the tympanitis subsides, the abdomen becoming more supple. The length of time that the congestive condition of the bowel will continue after a strangulated portion of intestine has been reduced is very considerable. In a case of strangulated femoral hernia which was some time ago under my care, reduction was effected, but strangulation recurring at the end of twelve days an operation became necessary; this was performed, and the patient died on the eighth day after it, or the twenty-first from the first strangulation. On examination, the small intestine was found congested in two distinct portions, each of which was about eight inches in length, and had several feet of healthy gut intervening. One of these congested portions lay opposite the wound, and was evidently the intestine that was last strangulated. The other was alto- gether away from the seat of operation, but was equally darkly congested, being almost of a black color, and was clearly that portion which had been constricted some time previously; and which, although twenty days had elapsed, had not as yet recovered itself. After the taxis has been fairly employed for a sufficient time, and has not succeeded in reducing the hernia, the operation must be proceeded with. It is impossible to lay down any definite rule as to the time that it is prudent to con- tinue efforts at reduction, but it may be stated generally that after the different adjuvants of the taxis the surgeon may think it desirable to apply, have been fairly tried and have failed, the operation should be undertaken without further delay. There are few surgeons who will not at once acknowledge the truth of the remark of the late Mr. Hey of Leeds, — that he had often regretted per- forming this operation too late, but never having done it too early. It is true that cases are occasionally recorded, in which after four or five days of treatment the hernia has gone up; but how rare it is to meet with such cases in practice; and in all probability in delaying the operation in the hope of finding one such case, the lives of dozens of patients would be sacrificed. Mr. Luke has shown as the result of the experience at the London Hospital, that the ratio of mor- OPERATION FOR STRANGULATED HERNIA. 781 tality increases greatly in proportion to the length of time that the strangulation is allowed to continue. Of 69 cases of strangulated hernia operated upon within the first 48 hours of strangulation, 12 died, or 1 in 5-7; whilst of 38 cases operated on after more than 48 hours had elapsed, 15 died, or 1 in 2-5. Indeed, one chief reason of the greater mortality from operations for hernia in hospital than in private practice, probably arises from the fact that much valuable time is frequently consumed before assistance is sought, or in fruitless efforts to reduce the swelling before the patient's admission. Not only is time lost in this way, but the bowel is often bruised and injuriously squeezed, so that inflammation already existing in it is considerably increased. Fig. 309. OPERATION FOR STRANGULATED HERNIA. The operation for strangulated hernia may be performed in two ways; either by opening the sac, exposing its contents, and dividing the stricture wherever it is situated, from within ; or, it may be done by divid- ing the stricture outside. without opening the sac. In either case the great object of the operation, the division of the stric- ture by the knife, is the same; but the mode in which it is effected is dif- ferent. We shall first de- scribe the operation in which the sac is opened —afterwards that in which it is not; and then briefly compare the two pro- cedures. Operation. The patient having been brought to the edge of the bed, or placed on a table of convenient height, the bladder should be emptied, and the parts that are the seat of operation shaved. An incision of sufficient length is then made over the neck of the sac; this may be best done by a fold of skin being pinched up, transfixed by pushing the scalpel across its base with the back of the instrument turned towards the hernia, and then cutting upwards (fig. 309); a linear incision is thus made which may be extended at either end if necessary; the dis- section is then carried through the superficial fascia and fat with the scalpel and forceps. If any small artery spout freely, it had better be tied at once, lest the bleeding obstruct the view of the part in the subsequent steps of the operation. As the surgeon approaches the sac, more caution is required, more particu- larly if the sub-serous cellular tissue is dense, opaque and laminated. The surgeon must pinch this up with the forceps, make a small incision into it, introduce a director, and lay it open upon this, or on the nnger (fig. 310). If it is thin and not opaque, so as to admit a view of the subjacent Fig. 310. 782 STRANGULATED HERNIA. parts, he may dissect it through with the unsupported hand. In this way he proceeds until the sac is reached, which is usually known by its rounded and tense appearance, its filamentous character, and by the arborescent arrange- ment of vessels upon its surface. In some cases the surgeon thinks that he has reached the sac, when in reality he has only got upon a deeper layer of condensed cellular tissue in close contact with it; here the absence of all appear- ance of vessels, the dull and opaque character of the tissue and its more solid feel, together with the absence of the peculiar tension that is characteristic of the sac, will enable him to recognize the real state of things. In other cases again it may happen that the sac is so thin, and the superficial structures so little condensed, that the surgeon lays it open in the earlier incisions before he thinks he has reached it. Under these circumstances a portion of the intes- tine protruding might be mistaken for the sac. This dangerous error may be avoided by observing the peculiar smooth and highly polished appearance presented by the dark and congested gut; the absence of arborescent vessels and the non-existence of any adhesions between its deeper portions and the tissues upon which it lies. If the sac is prematurely opened and omentum protrudes, the granular appearance and peculiar feel of this tissue will at once cause its recognition. The sac having been exposed, must be carefully opened; this should be done towards its anterior aspect; and if it be a small one, at its lower part. It may best be done, if the sac be not very tense, by seizing a portion of it between the finger and thumb, and thus feeling that no intestine is included; a small portion of it is then pinched up by the forceps, and an opening is made into it by cutting upon their points with the edge of the scalpel laid horizontally. If the sac be very tense, it cannot be pinched up in this way, and then it may best be opened by introducing the point of a fine hook very cautiously into its substance, raising up a portion of it in this way, and then making an aperture into it. There is little risk of wounding the gut in doing this, for, as the tension of the sac arises from the effusion of fluid into it, a layer of this will be interposed between it and the gut. In these cases, the fluid sometimes squirts out in a full jet, and occasionally exists in a very considerable quantity. I have seen at least a pint of slightly bloody serum escape on opening the sac of an old strangulated ingui- nal hernia. Most frequently, however, there is not more than half an ounce to an ounce, and sometimes the quantity is considerably less than this. In some instances, scarcely any exists, and then it becomes necessary to proceed with extreme caution in opening the sac, as the gut, or omentum, is applied closely to its inner wall. In such cases as these the sac is not unfrequently sufficiently translucent to enable the surgeon to see its contents through it, and he should then open it opposite to the omentum or to any small mass of fat that he may observe shining through it. The opening once having been made into the sac, Fig. 311. may be extended by the introduction of a broad director (fig. 311), upon which it is to be slit up to a sufficient extent to admit of the examination of its contents. The next point in the operation is the division of the stricture; and this requires considerable care, lest injury be done to the neighboring parts of im- portance, or the gut be wounded. Vessels and structures in the vicinity of the stricture are avoided by dividing it in a proper direction, in accordance with ordinary anatomical considerations, which will be described when we come to speak of the special forms of rupture. All injury to the intestine is prevented by introducing the index-finger of the left hand up to the scat of stricture, OPERATION FOR STRANGULATED HERNIA. 783 insinuating the finger-nail underneath it, and dividing the constriction by means of a hernia knife, having a very limited cutting edge (fig. 312). If a Fig. 312. director be used to guide the knife, the intestine will be in considerable danger, as the instrument may be slid under that portion of it which lies beneath "the stricture, or the tense gut, curling over the side of the groove, may come in contact with the edge of the knife. These accidents are prevented by usin«t+hp *>lmno-p The suro-eon knows when he has entered an old false passage by the change that takes °pTace in the direction of the instrument, by its not reaching the 886 DISEASES OF THE URETHRA. Fig. 345. bladder, and by the rough sensation communicated to it, very different from that afforded by the smooth lining of the urethra. The patient is often conscious of the existence and of the entry of the instrument into the false passage, and will warn the surgeon of it. If the surgeon is aware that he has made a false passage, he, if possible, should at the time of the accident pass a larger cathe- ter into the bladder, and leave it there for a few days until the laceration has healed. If there be an old false passage, he must be careful, by keeping the point of the instrument away from it, not to enter it, lest during the introduc- tion of the catheter he raises with the point of the instrument the valvular angle that intervenes between it and the urethra; every time that this is opened up=it tends to lessen the chance of a closure of the aperture, whilst overlapping the urethra it interferes with the onward passage of the instrument into the bladder. By withdrawing the instrument, and changing its direction, the false passage may often be avoided, and the bladder reached. Should there have been much difficulty in getting it in, the better plan will be to retain it for two or three days, when the canal may possibly close. It has already been stated that in certain forms of stricture, dilatation does not succeed in effecting a permanent cure. In these cases two plans of treat- ment have been recommended, the destruction of the stricture by caustic, and its division by the knife. 2d. In the treatment of stricture by caustics two objects are endeavored to be attained; the first is the destruction of the stricture; the second, the diminu- tion of the sensibility of the surrounding mucous membrane, so that the irrita- bility and spasm of the canal may be lessened. The following is the way in which the caustic is applied. A wax bougie, well-oiled, is passed down to, but not through the stricture ; the surgeon then with the thumb-nail, makes a notch on that portion of the instrument opposite to the meatus. Another bouo-ie of similar length and size is then taken, and armed by a piece of potassa fusa, about the size of a small pin's head, being placed in a depression at its end. A mark is now made on it, at a point corresponding to the notch on the first bougie, it is then passed rapidly down until this mark comes opposite to the meatus, and then pressed firmly for two or three minutes against the stricture, upon which the caustic exercises its action. This appli- cation, which is followed by a gleety discharge, is to be repeated every seconder third day, until a proper sized bougie can be in- troduced ; and then the dilatation may be proceeded with in the usual way. This practice, stigmatized by Mr. Liston as " most atrocious," has now but few advocates, and indeed there appears to be nothing that it effects but what can be accomplished much more safely and easily by a catheter or sound in an ordinarily skilful hand. The division of the stricture may be practised either from within the urethra or from without, through the perineum. The division from within may be performed in two ways, 1st. By passing a concealed steel stylet down to the stricture, and then pushing for- wards the lancet-like knife, attempting to perforate the obstruc- tion. This plan is only applicable with safety to those strictures that are situated in that part of the urethra anterior to the scro- tum, where the canal is straight. In the deeper and more curved parts, any attempt at perforation would be fraught with danger; for as it would of course be impossible for the surgeon to guide the stylet exactly in the direction of the urethra, it would be as likely to perforate the walls of this canal as to pass through the stric- ture. In hard and resisting contractions, however, in the straight portion of the canal anterior to the scrotum, this instrument may occasionally be used with advantage. The most convenient form of cutting OPERATION FOR PERMEABLE STRICTURE. 887 stylet is the one figured here, which has a probe end, that is introduced through the stricture, and serves as a guide to the blade, which is projected and caused to retract into its cylinder by the action of a spring (fig. 345). Another mode of dividing strictures from within the urethra, is to pass a catheter containing a stylet through the stricture, and then projecting the stylet as the instrument is withdrawn, notching the obstruction. As the stricture how- ever must be of considerable size to admit of such an instrument as this; it is usually sufficiently amenable to other modes of treatment, and will therefore render such a procedure necessary. The internal division of the stricture has always been a favorite method of treatment in* France, and of late years not a few complicated and dangerous machines have been invented, by which a pro- cess of cutting or lacerating the division of the stricture is sought to be effected. Such contrivances are only mentioned in order to be condemned as in the last degree dangerous and improper. The division of the stricture from without by incision through the perineum, may be performed by two distinct operations: the one being only applicable to those strictures that are pervious to an instrument; the other to those which are impermeable. In the first case, a grooved staff is passed through the stricture and the section made upon this. In the second case the surgeon attempts to cut into and through the stricture, without any guidance except such as his anato- mical knowledge may afford him. Fig. 346. OPERATION FOR PERMEABLE STRICTURE. The first of these operations introduced by Mr. Syme as urethrotomy, and com- monly called the "perineal section," is a comparatively simple procedure. The instruments required for its performance are a staff, a No. 8 silver catheter, a pointed scalpel, and a broad director. The staff should vary in size from No. 1 to No. 6, according to the tightness of the stricture; it should be grooved along its convexity, either the whole of the way, or better, merely for *he lower third (fig. 346). The stem being smooth and of full size, and joining into the lower grooved part by a distinct shoulder, which being passed down as far as the stricture forms by its projection a guide to that part of the urethra requiring division. In those cases in which there are false passages a hollow staff may be advantageously used of the same size and shape; the flow of urine through it indicating with certainty its passage into the posterior part of the urethra. The operation is performed as follows: —The staff having been passed well through the stricture so that the shoulder rests against the upper part of the constriction, the patient is tied up as tor lithotomy, and the surgeon seating himself in front, pushes the scalpel, with the back of the blade downwards, into the mesial line of the perineum a little ahove the rectum, and cuts upwards for an inch or more in the raphe. The dissection is carried on very carefully exactly in the median line until the staff is reached, when the, knife, nms be entered into its groove behind the stricture, and carried forwards through this. The staff having then been pushed on to ascertain that all is free must be with- drawn, and a No. 8 catheter introduced which is to be kept :n for forty-e ght hours it must then be taken out, and at the end of ^\?**^^™^ dilated by the introduction every second day of a full-sized sl™ ^^J Urine escapes for some little time by the perineal »oi*on, b£ ** ^sheals by granulation, the flow of fluid gradually lessens and at last ceases entirely. The principal points to be attended to in this operationare - 1st. To see that the staff is fairly through the stricture, and to be especially careful in determining this if false passages exist. 888 DISEASES OF THE URETHRA. 2d. To cut carefully in the median line, where, as Mr. Syme has observed, a kind of septum exists even in the deeper structures of the perineum, and where there can be no danger whatever of dividing any artery of magnitude, which might happen if any lateral deviation of the knife took place. The only vessel indeed which is at all endangered is the artery of the bulb, and this may always be avoided by carefully keeping in the raphe, as it lies towards the side of the incision. 3d. To enter the point of the knife behind the stricture, and to divide that by cutting forwards in the groove of the staff. 4th. Not to turn the edge of the knife downwards; if this.be done the deep perineal fascia may be opened and danger of pelvic infiltration and inflammation incurred. 5th. Much difficulty has occasionally arisen in the introduction of the cathe- ter into the bladder after the division of the stricture. This may always be avoided by adopting the suggestion of Mr. Henry Thompson, of passing a broad director, with the groove turned up, into the posterior part of the urethra after the stricture has been cut, but before the staff is withdrawn. As the catheter is passed down the canal its point will infallibly be guided by this onwards into the bladder. When there are more strictures than one, the division of the deepest is usually alone necessary. Although fatal cases of perineal section have occasionally been recorded, yet this is nothing more than we must expect to happen from time to time in any operation that is performed on the urinary organs whilst diseased, more particu- larly if there be a granular condition of the kidneys, a state of things in which I have known the simple introduction of the catheter followed by death in six or seven hours. If I understand Mr. Syme right, it is with the view of pre- venting the ulterior inevitable fatal consequences of all intractable strictures that he has proposed this plan of relieving the obstruction, by dividing it from without, in those cases in which ordinary methods notoriously fail, and in which there is no alternative but to perform urethrotomy, or to leave the patient to his fate. In order that this operation should be successful we must not wait for the occurrence of those changes that are the result of the chronic obstruction, such as disease of the bladder and kidneys, and which must inevitably increase the danger of any operation; but we must divide the stricture with a view of pre- venting them. The most important question in connection with this operation, is in what class of cases it should be practised. That most strictures may be cured by dilatation, there can be no doubt; most practitioners holding with Liston, that whenever a catheter can be got through a stricture, its cure by dilatation is in the surgeon's hands. Though this may be generally true, instances not unfre- quently occur, however, in which dilatation fails to effect a cure; the stricture, as I have already remarked, being highly contractile, and not admitting of expansion beyond a certain point, relapsing whenever the dilating means are removed. In other cases also the patient suffers so much pain and irritation whenever an instrument is passed, that he cannot bear the repeated introduc- tions which are necessary if the stricture be complicated with fistulae in perineo or false passages, and which render its cure by dilatation tedious and almost im- practicable. In such cases as these the surgeon, being unable to benefit his patient materially by dilatation, must choose between the employment of ure- throtomy and palliative means. There are four classes of cases in which urethrotomy may be advantageously employed. 1st. In very old dense cartilaginous strictures, often of traumatic origin, which admit an instrument with great difficulty, and cannot be dilated beyond a certain point, owing to the conversion of the urethral structures into a kind of dense, PERINEAL SECTION. 889 fibrous, almost cicatricial tissue, that neither admits of expansion nor of absorp- tion by the pressure of instruments; and in which a considerable extent, half an inch or more, of the urethra is involved. 2d. The same kind of stricture complicated with fistulae in the perineum or scrotum, with perhaps considerable plastic infiltration of these parts. 3d. Very tight strictures accompanied by excessive sensibility of the urethra; in which each introduction of the instrument is attended by intense suffering, spasmodic movements of the limbs and rigors, so that the patient cannot be induced to submit to a proper course of bougies. 4th. Very elastic, though perhaps narrow strictures, that can be dilated readily enough, even up to the admission of full-sized instruments; but which when the treatment is discontinued immediately begin to contract again, so that the patient is never out of the surgeon's hands and sees no prospect of cure. The whole value of the " perineal section" will at last depend on the liability of the stricture to return after its division, and this point has not as yet been by any means satisfactorily determined. The ultimate result of the cases in which it has been practised has not as yet been fully laid before the profession, and until this has been done we cannot consider the utility of the operation as established, except as a means of temporary relief in cases of the kind just men- tioned. Much will certainly depend upon keeping up dilatation of the urethra for some months after the division of the stricture, a catheter of full size being passed once in a week or ten days. If this precaution be neglected, relapses will often occur; and even when scrupulously attended to they are, I believe, by no means unfrequent. In order to perform the perineal section it is necessary that the stricture should be pervious to a grooved staff, however small this may be; and this it might be supposed would limit materially the cases in which the operation can be performed. But complete obliteration of the urethra cannot take place except as the result of sloughing, usually consequent on injury; indeed "im- permeable" strictures, though frequently spoken of, are very rarely met with. Mr. Syme, indeed, denies their existence, and states that if urine can escape through a stricture, a bougie can be got in. A surgeon may often be foiled in his first attempts in getting an instrument through a very tight stricture, but 1 believe that with patience, by attention to constitutional treatment, so as to lessen urethral irritation, and especially by the administration of chloroform, he will usually at last succeed in getting an instrument of some kind through the very worst strictures. In the first case in which I performed the perineal sec- tion, almost all the urine had for twelve years been discharged through fistulous openings in the perineum and scrotum; and the principal portion escaped through a large hole on the inside of the left thigh, a few drops merely occa- sionally passing out by the lips of the urethra. No instrument had been passed for four years, though repeated attempts had been made by different surgeons Being foiled in getting a catheter into the bladder the first time I tried, I kept the patient in the hospital for two or three weeks, attending carefully to his constitutional condition, but without making any further effort He was then placed under chloroform, when I succeeded in passing No. 1. Ihe urethia was then dilated up to No. 5, beyond which no instrument could be passed when the perineal section was performed. The patient made an excellent erne he fistukms openings closing, and the urine being discharged by the natural^channel In another^ case* which I attended with Mr. Bryant, persevering attempts had been made for five years to get an instrument into the b adder ^ ^out uc cess, the stricture not only being excessively tight, but the urethra.acutely sensitive; under chloroform I succeeded in getting No^ 1 f™™****'?* the bladder, and speedily cured the patient In a case of ^™U°ne°J_u™ following stricture, consequent on injury of the perineum, sent to me by Mr Corrie of Finchley in which no catheter had been introduced for eight years, it 890 DISEASES OF THE URETHRA. was found after death that although the urethra had been converted into a mass of cicatricial tissue at the part injured, yet that it was permeated by a narrow tortuous passage, through which the urine had escaped. The influence of anaesthetics in facilitating the passage of instruments through apparently impermeable strictures, is very marked. Shortly after the introduc- tion of ether as an anaesthetic agent, Mr. Liston was going to cut through a stricture that had resisted all attempts made by his most dexterous hand at get- ting an instrument into the bladder; but no sooner was the patient put oh the table and fairly rendered insensible, than the No. 8 silver catheter, which had been passed down as far as the stricture, and the point of which was to serve as a guide to the knife, slipped into the bladder, and thus rendered a dangerous operation unnecessary. But yet no surgeon can doubt that cases do occasionally though rarely occur, in which, in consequence of extravasation of urine and old inflammatory action, the urethra has become so tortuous and narrow, and the perineum so indurated and disorganized, that an instrument cannot be got through, even though urine pass out readily. It must be borne in mind that a stricture may be permeable to urine, but impermeable to a catheter, even in the most dexterous hands. It does not follow necessarily, that because a fluid will trickle out of a narrow and tortuous channel, that a catheter or solid sound can be passed into it from without. Hence cases will occasionally occur in which the perineal section is not practicable. In the event, therefore, of a stricture being so tight and tortuous that no instrument can be got through it, or where a portion of the urethra having sloughed away, its canal is obliterated, neither the cure by dilatation nor urethrotomy can be performed, and it may then be necessary to have recourse to incision of the stricture without a guide. OPERATION FOR IMPERMEABLE STRICTURE. This operation is performed as follows: A No. 8 silver catheter is passed down to the stricture, the patient is then tied up as if for lithotomy, and the surgeon sitting in front, pushes a bistoury, with the back turned towards the rectum, into the raphe of the perineum as far as the apex of the prostate, so as, if pos- sible, to open the dilated urethra behind the stricture. He then cuts forwards through the stricture on to the point of the catheter, and thus having opened a passage, endeavors to pass that instrument on into the bladder. It is often extremely difficult to find the posterior part of the urethra; but in some cases this part of the operation may be facilitated by passing a grooved director or straight female catheter into it to act as a guide. When the tissues of the perineum are hard and gristly, altered by the effusion of plastic matter, and condensed by repeated attacks of inflammation and the existence of fistulae, it is a most difficult matter to dissect through such an altered mass and hit the urethra beyond it; and the difficulty is still further increased by the bleeding, which is often profuse. This operation, I have no hesitation in saying, is per- haps the most troublesome in surgery. I have more than once seen the most skilful operators foiled in their endeavors to accomplish it, and compelled to relinquish the operation without concluding it, or only succeed after prolonged and most painful attempts. Fortunately this operation is now scarcely ever necessary; with patience, and under chloroform, the surgeon may almost inva- riably get a staff, however small, into the bladder; he then has a sure guide upon which to cut, by following which he must certainly be led through the stricture into the urethra beyond it. In all cases, therefore, urethrotomy should, if practicable, be substituted for the division of the stricture without a guide. COMPLICATIONS OF STRICTURE. 891 COMPLICATIONS OF STRICTURE. 1st. Retention of urine has a tendency to occur in all tight strictures, by the gradual and progressive contraction of the canal. It most usually, however, takes place in consequence of a congestive or spasmodic condition being super- added to the organic constriction. It commonly happens that a patient having a moderately tight organic stricture commits an excess, or becomes exposed to cold and wet, and thus gets such a congested condition superadded, that the urine will not pass at all, or only in such small quantity by drops, and with so much pain and straining, that the bladder cannot be completely emptied. In these cases, the retention always eventually becomes complete; the bladder speedily fills, rises up above the pubes, with much distress and constitutional disturbance; and, if relief be not afforded, the distended portion of the urethra behind the stricture will ultimately give way, and extravasation of urine ensue. Under these circumstances, it becomes imperatively necessary to empty the patient's bladder as speedily as possible. The treatment to be adopted varies with the severity of the symptoms and irritability of the patient. If the retention have not continued very long, and if the patient be not very irritable, an endeavor might be made at once to give relief by passing a small catheter into the bladder. In this the surgeon may often succeed more readily than might have been expected, the stricture fre- quently yielding before an instrument, more easily when there is retention than when this condition does not exist. Even if the catheter do not enter the bladder, its point or that of a catgut bougie merely being got well into the stricture, it will generally happen, as Sir B. Brodie has pointed out, that on the withdrawal of the instrument, the urine will follow in a full stream; but it a sufficiently small catheter be used—in many cases not larger than halt ot JNo. 1 is admissible —the instrument may usually be got fairly into the bladder, it the patient be very irritable, it is better, before attempting the introduction of the instrument, to give him an opiate enema, consisting of £j 0* laudanum in about §ij of starch, and to put him in a warm hip-bath; the introduction of the catheter may now be attempted, and will very generally succeed Should it still fail, the effect of the inhalation of chloroform should be tried, when it almost invariably may be made to pass without the employment of anygr eat or dangerous degree of force. There are no cases in surgery in which chloroform I of more value than in these; under its influence it is Beldoin indeed Aat the catheter will not pass. After the instrument has been got into the bladder it should be left there, being tied in by means of tapes passing from^its rings under the patient's thighs, to a bandage that is passed round his waist. Anti- phlogisti Remedies must'then be employed in rather an active manner a free Lr-e leeches to the perineum if there be tenderness in this region, and salines with antimony The catheter will be found to be loosened at the end of forty- Tight hTs when it should be withdrawn, and the cure by dilatation proceeded WilV^rlWsu'rCTeon is unable to introduce a catheter in the ordinary way^^^ pass it down to the, t™ure and h n by-,*~ *• .P ^ „ ""V1: the v£caS 7uTh™e point of the instrument into the tissues Troundlh neckof the-'bladd-er or the prostate, and thus mduetng great, and 892 DISEASES OF THE URETHRA. perhaps even fatal, mischief in these regions. If he should, by some fortunate accident, get into the bladder, it is not by any skilful, though forcible, expan- sion of the stricture, but rather by perforating the urethra, and burrowm" through the corpus spongiosum and prostate, " tunnelling," as it has been termed, until he again enter that canal, or in some such way reach the neck of the bladder. 2d. In the kind of retention of urine that we are now discussing, the safest mode of affording relief after the failure of the catheter, is to make an incision into the middle line of the perineum, and to open the urethra behind or through the stricture. In doing this there is often much less difficulty in cases of retention than when the bladder is empty. In consequence of the urethra being distended by the accumulation of urine, and by the straining of the patient, it sometimes attains a considerable magnitude, though, if this be not the case, the operation may prove a very serious and difficult one. The operation, which is essentially the same as that described at p. 890, for impermeable stricture, is performed by passing a catheter down to the stricture; opening the distended sinus of the urethra beyond this; cutting upwards through the stricture upon the end of the instrument; and then passing the instrument on into the bladder, or allowing the urine to flow from the aperture thus made in the peri- neum. In doing this, care must be taken to keep strictly in the direction of the mesial line, so as not to wound vessels of importance. One advantage of this operation is, that the stricture may by it be cured at the same time that the retention is relieved; and as the incisions do not extend into the bladder, but are limited to the urethra, there is less danger to the patient than when that viscus is opened. Another advantage of the perineal incision in these cases is, that it not unfre- . quently happens that urinary abscess has begun to form, or the extravasation of a few drops of urine has taken place sooner than the surgeon may have had any idea of; and if so, the incision through the perineum will afford an exit for any extravasated matters, at the same time that it relieves the patient from the distress and danger of the retention. Should any mischief of this kind have taken place, it is not necessary to be so particular about opening the urethra with the knife, for an aperture having already been established in it, the urine will readily flow through the artificial channel thus formed by free incision into the inflamed or suppurating perineum. 3d. The relief of retention from stricture may also be obtained by puncturing the bladder through the rectum. After emptying the bowel by means of an enema, the surgeon passes the left index finger well into the gut, feeling for the posterior margin of the prostate; he then carries the trochar and canula, which are long and somewhat curved, upon this as a guide, and when the extremity of the instrument has reached the posterior edge of the prostate, pushes it upwards into the bladder (fig. 340,6). In introducing the instrument into the rectum, the surgeon should withdraw the point of the stylet into the canula, so as to avoid wounding the gut, and not push it forwards until he has the end of the canula fixed against the spot where he intends to make the perforation. After withdrawing the stylet and emptying the bladder, the canula should be tied in by means of tapes, and left for a few days until means can be taken to restore the passage through the stricture, when it must be withdrawn and the aperture left to close. In performing this operation the surgeon perforates the bladder in that portion of its fundus which is uncovered by peritoneum, being bounded behind by the reflection of the serous membrane, anteriorly by the prostate, and on either side by the vesiculae seminales. In order to avoid wounding any of these structures, he should keep strictly in the mesial line, and puncture immediately behind the prostate. This operation has the advantage of being far easier of performance than the last, and may doubtless occasionally be required in those very rare cases of EXTRAVASATION OF URINE. 893 retention from stricture in which.there is no sign of abscess or extravasation in the perineum, in which the urethra appears not to be dilated behind the stric- ture, in which the prostate is not enlarged, and in which, under chloroform, and with patience, a catheter cannot be got into the bladder, a combination of cir- cumstances that will but very rarely indeed occur to a surgeon skilled in the use of his instruments. 2d. Extravasation of urine.—In consequence of the ulceration or disorgani- zation of the coats of the urethra, this canal may give way behind the stricture, and the urine become infiltrated into the surrounding tissues. The part of the urethra that gives way is invariably the membranous portion of the canal, just anterior to, or between the layers of the triangular ligament, where it is weak, being least supported by surrounding structures, and usually most dilated and attenuated by the pressure to which it has been subjected. This circumstance is a strong argument in favor of the opinion that stricture of the urethra never occurs at or behind the deep perineal fascia; did it do so, we should necessarily have extravasation of urine in a deeper situation than we do. Were it possible for the urethra to give way altogether behind the deep perineal fascia, the urine would become effused into the cavity of the pelvis. But as it is, the connection of the triangular ligament with the rami of the pubes and ischium prevents the extension of the infiltrated urine in that direction, and the manner in which the superficial fascia of the perineum is connected with the deep fascia uniformly causes the fluid to take a course forwards into the perineum, scrotum, and up- wards upon the external organs of generation, the groins, and the anterior abdominal wall; ascending contrary to its gravity rather than soaking back into the more dependent parts of the body, as it would do, were it not for the particular connection of the fasciae that has just been alluded to. I have, how- ever, known the superficial fascia to give way, and the urine then gravitating backwards give rise to extensive sloughing in the ischio-rectal fossae and about the nates, denuding the rectum. The effects of urine that has become acrid and concentrated by long retention are most deleterious upon those tissues with which it comes in contact. The vitality of whatever portion of cellular tissue it infiltrates is immediately de- stroyed by it, the tissue becoming converted into a kind of putrid stringy slough, intermixed with and soddened by a quantity of fetid dark-colored acrid pus and urine. The ravages of extravasated urine are often extensive; the urethra giving way suddenly behind the stricture, the fluid is driven with all the force of the vital and physical contractility of the over-distended bladder into the perineum, and thence rapidly finds its way through the scrotum upwards. In other cases, again, the extravasation occurs more slowly; a few drops appear first of all to escape from the urethra through a small rent or ulcer in it; these give rise to inflammation in the surrounding structures, by which the progress of the extravasation is for a time limited. It is especially upon the cellular tissue of the scrotum that the effects of the extravasation manifest themselves in their full intensity, causing great distension and rapid sloughing of it. The skin speedily participates in this action, becoming of a dusky-red or purple color, and then falling into a state of gangrene. In this way the testes may become denuded, and the cords exposed. It is remarkable, however, if the patient survive these destructive effects, with what rapidity the reparative action goes on in this region. It is seldom that infiltration extends higher than the groins, or the anterior portion of the abdominal wall; but it may run up as high as the costal cartilages before proving fatal. When the extravasation is deep, the urethra being opened between the layers of the triangular ligament, the patient experiences a sensation as if something had o-iven way in the perineum, with much throbbing and pain; there may be but little swelling for a day or two, but then a doughy diflused intumescence takes place, with rapid extension forwards. When the rupture is altogether 894 DISEASES OF THE URETHRA. anterior to the deep perineal fascia, then rapid swelling and infiltration take place, partly urinous, partly inflammatory, of the scrotum and penis; these parts become enormously distended, oedematous, crackling, and emphysematous, with the local signs that have already been mentioned. The constitutional disturb- ance is always considerable; at first of an irritative type, but speedily followed by asthenic and typhoid symptoms, by which the patient is at last carried off. The treatment consists in making a free and ready outlet for the urine as early as possible. This should be done as soon as the extravasation is known to have occurred, by a deep incision into the middle of the perineum. So soon as any pain and throbbing, with diffused swelling, occur in the perineum, the sur- geon should introduce his left index finger into the rectum, so that the gut may not be wounded, and then pushing a long sharp-pointed bistoury deeply in the raphe of the perineum, cut upward to a sufficient extent into the extravasation, and in the direction of the urethra. A catheter should then, if possible, be introduced and secured in the bladder; in this way no further effusion can occur, an outlet will be afforded to matters already effused, and the greater part of the urine will commonly be found to escape after a time by the aperture thus made. Should the case not be seen until extravasation has spread widely, a free inci- sion should not only be made into the perineum, but also into the scrotum on either side of the septum, into the penis, and wherever else swelling is observed. The sole chance of safety for the patient lies in making these free incisions, through which the parts may, to a certain extent, empty themselves. How- ever extensive the infiltration and serious the mischief may be, we need not despair of the patient if a free outlet can be obtained for the acrid and putres- cent urine and effused matters, and in order to secure this, the infiltration must be followed by incisions as high as it extends. The parts must, at the same time, be covered with chlorinated and yeast poultices, and the constitutional powers of the patient must be supported by good nourishment and a sufficient supply of stimulants. If the patient survive the immediate impression upon the system produced by the gangrene and the urinary infiltration, he must be prepared to go through a severe trial to his constitutional powers, in the separation of the sloughs, the profuse discharge, and other sources of irritation that are set up. During this period he will require abundant support; the brandy-and-egg mixture, ammonia and bark, with any nourishment that he can take; and much attention should be paid to the removal of the sloughs, the giving a ready outlet to the dis- charges, and to keeping the patient as clean and as free from all local irritation as possible. 3d. Urinary abscess may be considered in many cases as a limited effusion of urine mixed with pus, and circumscribed by plastic matter that is deposited in the tissues with which the urine comes in contact. It is generally occa- sioned by the irritation of the passage of instruments, but may arise simply as the effect of stricture, or from inflammation of some of the urethral follicles. From some cause of this kind a small abrasion or aperture forms in the urethra, a drop or two of urine escapes into the subcutaneous cellular tissue, this becomes bounded or circumscribed by plastic deposit around it, so that extravasation does not occur. Such an abscess as this may form at any part of the urethra, but it is most frequently met with in the perineum, appearing to take its origin from the bulb or membranous part: such an abscess is rarely dangerous, but is chiefly of consequence by being commonly followed by urinary fistula. A urinary abscess is indicated by the formation of a small, somewhat circum- scribed, hard, and painful tumor, situated in the neighborhood of the urethra. It is usually unattended by constitutional disturbance, unless it attain any con- siderable bulk, when some pyrexia may ensue. It is principally in the perineum that it attains any degree of magnitude, then constituting a perineal abscess, characterized by a deeply-seated, hard, tense tumor, brawny and without fluctu- URINARY FISTULA. 895 ation; attended by considerable weight and throbbing in this region. It does not readily point, owing to the manner in which it is bound down by the super- ficial fascia. In the treatment of these abscesses early incision is required; when occurring in the scrotum or anterior to it, the surgeon should wait for fluctuation; but when they are seated in the perineum, he need not do so, making a free incision into the hard, brawny mass, which must then be well poulticed. 4th. Urinary fistulae commonly form in the perineum and scrotum as the result of abscess in these regions communicating with the urethra; occasionally, however, they are met with in other situations, as in the groin, the anterior abdominal wall, or the inside of the thigh. They usually communicate with the bulb, or membranous portion of the urethra, but occasionally occur anterior to this. In number they vary considerably; when occurring in the scrotal and penile portions of the urethra, they are usually single; but when in the perineal, they are often pretty numerous; several apertures being occasionally met with about the perineum, scrotum, and nates. In one case Civiale found as many as fifty-two. Their size also differs considerably, some only admitting the finest probe, whilst others are large cloacae. In a case recently under my care the patient had a tunnel of this kind in the groin that would readily admit three fingers. They are usually tortuous, elongated, and narrow, sometimes con- stricted externally and more widely dilated behind. The surrounding parts are greatly condensed, the whole of the scrotum and penis enormously enlarged, indurated, and almost cartilaginous in structure. The urine may escape almost entirely through them, scarcely any being discharged through the urethral orifice; or there may be but a slight exudation from the fistulous openings. The treatment of urinary fistula varies according as it is complicated with stricture, and as it is situated in the anterior or posterior parts of the canal. If there be a stricture, this, as the cause of the fistula, will require removal either by dilatation or the perineal section. If the stricture is not very tight and hard, dilatation commonly succeeds; the instrument being introduced every second or third day, until the urethra is dilated to its normal size, when the fis- tulous tracks will in many cases close. In some instances, however, the fre- quent introduction and withdrawal of the catheter is a source of irritation, and then it had better be left in. When this practice is adopted a moderate sized elastic catheter should be used. If this be too small, the urine will flow between it and the sides of the urethra, and thus escape through the fistulae; if too large, it stretches the urethral orifice of the fistula injuriously. If the stricture be very tough and irritable, the better plan is to perform urethotomy at once, as in this way we remove all obstruction and give free exit to the urine, which instead of escaping by tortuous and sinuous passages, finds its way out readily through the new aperture that has been made. The fistulae, especially if small and recent, will sometimes heal kindly enough after the removal of the obliteration, but if extensive, old, and cartilaginous they are of course little disposed to take on reparative action; and although the cause that in the first instance gave rise to them may be removed, yet they constitute an independent affection which requires special treatment for its cure. The special treatment for urinary fistula, must vary according to the size of the canal, but more particularly with regard to the part of the urethra with which it communicates; whether it is a perineal, scrotal, or penile, fistula. If the fistula is perineal, and of small size, a probe coated with melted nitrate of siver, or a wire made red-hot in the ordinary way, or by the galvanic current, and passed down it occasionally, may cause its contraction If large, a gum-catheter should be kept in the bladder, and the edges of the fistula freely rubbed with the nitrate of silver, or deeply pared and brought together by ^When^hefistula is scrotal it often requires to be laid open, and to be made , 896 DISEASES OF. THE URETHRA. Fig. 347. Fiq. 348. to granulate from the bottom, when it may be found to communicate with large sloughy and ill-conditioned cavities in this situation. When penile, the fistula is usually much more troublesome to heal, its edges are thin, and the track is short and shallow. Urethroplasty may in such cases be advantageously prac- tised. Operations of this kind require for their success very careful management and minute attention to detail; they very commonly fail in consequence of a small quan- tity of urine or of mucus es- caping through the wound, and thus interfering with union of its lips. Urethroplastic operations must be varied according to the situation and the size of the fistula. In all cases a full- sized gum catheter should be passed into the bladder and properly secured there. It should be left without a plug, so that no distension of the bladder, and consequent like- lihood of escape of urine be- tween the urethra and the instrument may take place. In order to prevent urinous diffusion over the integuments of the penis and scrotum, a vulcanized india rubber tube should be attached to the end of the catheter, by which means the flow of the urine is directed away from the patient. If the fistula be in the perineum or scrotum, the parts around being thickened, and indurated, its closure may often be attained, by freely and deeply paring the edges, and then bringing them together with the quilled suture. When the fistula is penile, there is not sufficient thickness of parts for ready union. In these cases Nelaton has recommended the following operation, which I have successfully practised. The edges of the fistula having been pared, the skin around to the extent of about one inch must be dissected up sub- cutaneously (fig. 347) through an opening made below the fistula, the edges of which must then be brought together by a few points of suture. The displacement of the skin causes granulations to spring up by which the fistula is closed. This procedure may sometimes be advantageously modified by paring the edges of the fistula, making lateral incisions, and then passing across but underneath the flap a slip of india rubber to prevent contact of the urine disturbing the adhesions (fig. 348). URINARY VAGINAL FISTULAS. Preternatural communications between the urinary passages and the vagina commonly arise from injurious pressure upon and consequent sloughing of the anterior wall of this canal, to a greater or less extent during parturition. They may, however, occur from idiopathic abscess, or from malignant disease involving these parts. Urinary vaginal fistulae are essentially of two kinds, according as the com- munication is established between the urethra or the fundus of the bladder and the vagina. Hence they may be divided into urethral and vesical. TREATMENT OF V E S I C O-V AG I N AL FISTULA. 897 The urethrovaginal fistule are, so far as my observation goes, of most common occurrence, and this is readily explained by the fact that the urethra passes along the anterior aspect of the vagina for some distance before it terminates in the bladder, and occupies that portion of the vaginal wall that is most likely to be compressed during labor, under the arch of the pubes. These fistulae are usually of small size and linear. The vesico-vaginal fistule establish a communication between the neck or fundus of the bladder and the vagina. They are consequently situated further back than the other, and are usually larger and more ragged. The existence of a urinary fistula in the vagina, is always a source of serious discomfort and distress to the patient. The dribbling of urine through the preternatural aperture is generally continuous, although if this be situated far back behind the orifices of the ureters it might be somewhat intermittent, a flow taking place as the lower portion of the bladder fills. The incontinence of urine thus produced, gives rise to irritation and excoriation about the external parts, and occasions a strong ammoniacal odor to hang about the patient. The precise seat and extent of the fistulous opening, are best ascertained by examination with a bivalve speculum, or with a conical one having a slit made at its upper part, at the same time that the introduction of a bent probe, or of a female catheter into the urethra, will guide the surgeon to the artificial opening in the urinary passage. Treatment.—The cure of one of these vaginal fistulae can only be effected by causing a coalescence of their sides. When small and urethral, this may some- times be effected by touching the walls of the aperture with the electric cautery or a red-hot wire, introduced between the blades of an open speculum, and repeating this application once a fortnight or three weeks, until a cure is effected. When the fistula is larger, and especially when vesical, its cure can only be accomplished by paring the edges, and bringing them together with sutures, and thus attempting to procure union by the first intention. In effecting this, however, two difficulties present themselves: — The sutures either cutting their way out too soon, or the trickling of urine between the freshly pared edges, in- terfering with adhesion. In order to overcome these difficulties, a variety of ingenious contrivances have been introduced by different surgeons. The most useful of these are, in my opinion, Mr. Brookes' bead sutures, and the " clamp suture " of Dr. Marion Sims. The treatment recommended by Dr. Marion Sims leaves little to be desired in the management of these cases; Dr. Sims uses a suture of fine silver wire, well annealed, which after being introduced across the lips of the wound, is properly fixed to leaden or silver cross bars; these sutures are introduced by passing a silk thread by means of a nevus or corkscrew needle, about half an inch from the freshened edge of the fistula, and bringing it out through a cor- responding point on the other side of the fistula, without having transfixed the mucous membrane of the bladder. As many threads as necessary having been passed in this way, a piece of silver wire about eighteen inches long is attached to the silk, which is then drawn out, leaving the wire to occupy its place, so that its centre corresponds to the fissure, and both ends hang out of the vagina. The uppermost free ends are then passed through holes made in a narrow silver or leaden bar, and clamped by having split shot fixed upon them in the same way as is done on a fishing line. The undamped wires are now drawn down until the bar is pulled close to the upper suture holes, and a second clamp is then fixed to these ends, and is pushed up against the lower suture apertures. In this way the edges of the fistula are brought and held together by a clamp on either side, which may be allowed to remain in from seven to ten days. These may then be removed by clipping off the flattened shots from the anterior 57 898 DISEASES OF THE URETHRA. clamp, which is thus detached from its bed. The posterior one, with the wires attached, may then be hooked up, pushed backwards, and lifted out of the vagina with forceps. In the after-treatment, especial attention is required; and here the great point is to prevent the contact of the urine with the edges of the fistula. With this view a catheter should be introduced, and worn in the bladder, so that no urine may collect in this organ. For this purpose, Dr. Sims has in- vented a very ingenious Fig. 349. catheter, represented in the annexed cut (fig. 349), which may be worn with more comfort, and with less chance of slipping than the ordi- nary instrument. After the patient has been put to bed, and the catheter introduced, a full opiate should be given, and continued throughout the treat- ment, with the view of preventing the action of the bowels, a point on which Dr. Sims lays much stress, and to which the success of his operations may be in a great measure attributed. It is very seldom that they are required to be opened for ten or fifteen days, provided the patient be kept on a rigid diet. During this treatment the catheter may be removed once or twice a day, in order to be cleansed and to be kept free from phosphatic or mucous accumulations, and free ablutions of the external genitals by sponge or syringe and warm water should be practised during the whole of the treatment. After the removal of the sutures, Dr. Sims advises that the catheter should be continued, and great care exercised not to move too soon, lest the weak cicatrix be strained. More recently a very simple and successful mode of closing these fistulae has been invented by Dr. Bozeman, of Alabama, by what he terms the " button suture." After paring the edges of the fistula, and passing silver wires across in the usual way, he draws the parts together by passing both ends of the wire Fig. 350. Fig. 351. through an aperture in a steel rod, which, being carried along them, closes the opening. A thin silver or leaden plate, " the button," properly perforated down the middle, is then slipped along the wires so as to cover the fistula (fig. 350), and split shot having been pushed along their free extremities, are pressed tightly against the button, the wires are then properly nipped, and the apparatus is left on for about ten days (fig. 351). TUMORS OF THE URETHRA. Small polypoid tumors are not unfrequently met with inside the urethral orifice. They have occasionally a gonorrheal origin, though they commonly arise irrespective of such disease. They are always very vascular, and are most frequently met with in or around the female urethra, where they are of a bright red color, have a florid hue, bleed freely when touched, and are composed of a URINARY DEPOSITS. 899 spongy kind of erectile tissue; they are commonly conoidal or oval, encir- cling the urethral orifice on one side, or even forming a complete zone around it. They grow slowly, and seldom attain a larger size than that of a raspberry. They are not unfrequently accompanied by a vast deal of sympathetic irritation, great pain in micturition, attended by an admixture of mucus or pus in the urine, uneasiness of the lower part of the abdomen, and often aching in the loins. These vascular tumors are far less frequent in the male than in the female urethra. When they occur in men, they usually constitute a small granular florid mass inside the orifice of the canal. When seated in or around the female urethra, these tumors not unfrequently give rise to very great and continuous irritation; much pain during and after making water, radiating through the whole pelvic region, and in fact many of the symptoms of stone; so that patients laboring under this affection are often sounded on the supposition of there being calculus. Vascular urethral tumors may be removed in four ways: — by excision, liga- ture, caustics, or the actual cautery. 1st. Excision. When situated within the male urethra, they should be snipped off with a fine pair of curved scissors. When situated in or around the female urethra, if of small size and pediculated, they may readily enough be removed by the scissors or dissected away, the canal of the urethra being encroached upon as little as possible. This operation is, however always attended or fol- lowed by very considerable and continuous arterial hemorrhage, which has even in some instances been of a fatal character. Hence when the tumor is of large size, and the patient weakly, excision should be practised with much caution. If it be done, the hemorrhage may be arrested by the introduction of a catheter into the urethra, and by firm pressure on the bleeding surface by means of a pad of lint supported by a "f" bandage. 2d. The Ligature is not a convenient mode of removing these growths, being difficult of application, very painful and tedious. 3d. Caustics, more particularly the strong nitric acid or the potassa cum calce may be very conveniently employed where the tumor is of small size and very vascular. In applying them, the upper wall of the canal must be protected by a broad director introduced along it. 4th. The actual Cautery is the most convenient agent for the removal of these growths from the female urethra. By it they are at once destroyed with- out hemorrhage, and the eschar that is formed protects the subjacent raw sur- face from the irritation of the urine. If situated deeply within the urethra and of small size, the galvanic cautery or a red-hot wire will most easily reach them; but if at or around the orifice, I always employ a small olive-shaped cautery. During its application the surrounding parts must be protected from the action of heat by spatulse, and the urethra by a director or silver catheter, which should be retained after the operation. CHAPTER LVIII. STONE IN THE BLADDER The urine is liable to the deposit of various solid matters which when amor- phous and impalpable are termed sediments; when crystaHine they cons^ute aravel and when concrete, form calculus or stone These deposits wbatever form they assume, are always the result of constitutional causes; and these con- 900 STONE IN THE BLADDER. stitutional conditions giving rise to them are commonly called diatheses. Of these, surgeons usually recognize three: the lithic, oxalic, and the phosphatic; besides these, however, others doubtless exist, the precise characters of which have yet to be determined. The lithic acid diathesis chiefly occurs in individuals of robust habit of body and florid looking, who have lived high and suffer from irritable gastric dyspep- sia. It is often associated with a gouty or rheumatic tendency, or with some of the more chronic forms of skin disease, especially psoriasis. It is charac- terized by scanty and acid high colored urine, which deposits on cooling two kinds of sediment, a yellow and a red. According to Lehmann, these sediments consist of urate of soda; but Golding Bird, and, I believe, most of the chemists in this country, regard them as lithates of ammonia. The yellow sediment, con- taining an admixture of the coloring matter of the urine, is usually dependent on slight disorder of the digestive organs and skin, coming and going under the influence of very trivial causes. The red sediment, owing its color, according to Bird, to an admixture of purpurine, a highly carbonaceous ingredient, and indicative of imperfect assimilation, is met with in persons of full habit, who live too freely. A variety, or rather an admixture of these sediments, consti- tute the lateritious deposit so common in gout and rheumatism. The red sand or gravel is a crystallized variety of the lithic acid sediment. It may be com- pared, in general appearance, to cayenne pepper, and under the microscope pre- sents the characters seen in fig. 352. It is not unfrequently met with in Fig. 352. Fio. 353. Lithic Acid. Litbate of Ammonia. children of a strumous habit, who are allowed more animal food than they can well assimilate. Occasionally crystals of lithic acid are found intermixed with these deposits, presenting the characters figured in 352. The calculi that occur in this diathesis are of two kinds; the lithic acid, and the lithate of ammonia. The lithic acid calculus is usually of small or moderate size, varying from a pin's head to a pigeon's egg; it is oval, somewhat com- pressed and flattened, smooth on the surface, and of a fawn color. On section it is seen to be laminated and to present various shades of a light brown or fawn tint. The lithate of ammonia calculus is of very rare occurrence; when met with, it is chiefly in children, and is composed of concentric rings, having a fine earthy appearance, and being clay-colored. The treatment of the lithic acid diathesis must be directed to the removal of the prime causes of this condition, viz., mal-assimilation, defective oxygenation of the blood, and the ingestion of too large a quantity of stimulating food. All this may be remedied by attention to ordinary hygienic measures; the patient OXALIC AND PHOSPHATIC DIATHESIS. 901 must live sparely, should avoid fermented liquors, especially red and effervescent wines, and abstain from sweets, pastry, &c. He should take plenty of out-door exercise, and keep the skin in healthy action by warm or vapor bathing, and the use of horse-hair gloves. The bowels must also be carefully regulated by means of saline and other aperients, with occasional alterative doses of Plum- mer's or blue pill; to which, if the constitution be peculiarly rheumatic or o-outy, some colchicum may advantageously be added. A very good aperient for general use in these cases, is 3j of Bochelle salt in giss of the compound decoction of aloes, taken at night or early in the morning; or a dessert-spoonful of the following powder every morning: R Pulv. Rhei, |ss., Potass, tartrat. gj., Mao-nesiae ustae, £ij., Pulv. Zingiberis, £j.; f. pulvis. The patient may also be directed to drink some of the natural alkaline waters, as those of Vichy or Fachingen. The Vichy waters, containing as they do a large quantity of car- bonate of soda, with free carbonic acid, are extremely serviceable for the correction of this diathesis. If they cannot be procured, a very good alkaline drink consists of 9 j of bicarbonate of potass and 5 grains of nitre dissolved in a tumbler of cold or tepid water, to which about 5 grains of citric acid, or a table- spoonful of lemon-juice may be added, and taken early in the morning or in the middle of the day. When lithic acid calculus has actually formed, it is not well to give the alka- line remedies too long, or in too large quantity, lest the stone rapidly increase in size by becoming encrusted with phosphates. The oxalic diathesis is characterized by the formation of oxalate of lime in the urine. It generally occurs in individuals in whom there is defective assimi- lation, dependent upon exhausted nervous energy, arising from over work, mental anxiety, or venereal excesses. The patient is usually pale and hypochondriacal, suffers from dyspepsia, acidity of stomach, and disturbed sleep. In these cases there is often loss of sexual power; a state of debility of the generative organs, con- nected either with the want of erectile vigor, or too speedy emissions. The urino is usually very pale, abundant, and acid, and there is heat and smarting during its passage along the urethra. In this dia- thesis there is no sediment or gravel pro- perly speaking, but the crystals float in the urine, subsiding however when it stands, but not occurring in sufficient quantity to constitute a true sediment (fig. 354). The oxalate of lime or mulberry cal- culus is usually of a dark brown or almost black color, moderate in size, being seldom larger than a walnut, and round; it is always rough, tuberculated, and sometimes almost spiculated on the surface. . . , .. • _ppp„-rv In tht treatment of this diathesis when there is no calcu ui; is n cessary to nut the natient upon a light and nourishing diet, especially fish, as recom- mended by Dr BirdTcautionlng him to avoid sweets and all fermented liquors, S the exception of a moderat! quantity of brandy. Tomes, -gcM rhP mineral acids iron, zinc, and quinine may be given, and the residence, n OT^Sr»^X^^^54.budte,«1^og ^T^V^t^^cteV ooeurs in old persons, or in those who are Fiq. 354. 902 STONE IN THE BLADDER. Aramoniaco-Magnesian Phosphate. prematurely aged, with a broken constitution and an anemic condition of the system. In this diathesis the sediment and Fia. 355. calculi may occur in three distinct forms. 1st. Triple or ammoniaco-magnesianphos- phate. 2d. The Phosphate of Lime, and 3d. The mixed phosphates, consisting of a mixture of the preceding varieties. The triple phosphates (fig. 355) usually occur in urine that is copious, pale and barely acid, sickly to the smell, and soon decom- posing and becoming very offensive. In other cases it is dark, alkaline, and mucous. This condition especially occurs in old people, is associated with much debility, irritability of mind, pallor, and anemia. The phosphate of lime sediment is not of such common occurrence; it usually occurs in pale, and offensive, readily putrescent urine, mixed with much mucus, and in some cases apparently produced by the mucous membrane of the bladder. The mixed phosphates commonly occur after injuries of the spine as the result of general impairment of the health, or in advanced cases of prostatic disease. They are occasionally met with in large quantity, forming a kind of mortar-like sediment in the bladder. The phosphatic calculi are very common, the most frequent is the mixed, or fusible calculus as it is termed, on account of the ready way in which it melts when exposed to heat. This calculus is friable, laminated, and has a chalky, or earthy look. The calculus composed of phosphate of ammonia and magnesia is not so common, it resembles the preceding pretty closely in its general charac- ters, but is whiter and has a more chalky look; the phosphate of lime calculus is extremely rare — it is laminated and harder than the other varieties. The treatment of the phosphatic diathesis consists principally in improving the digestive powers, and restoring the general strength of the patient by the administration of good food, wine, or beer. The exhibition of tonics, especially of nitric acid, should be attended to, and exercise in the open air enjoined. As there is usually much pain and irritability of Fia. 356. system in this diathesis, opium may advanta- geously be administered. Besides the calculi mentioned, various other kinds of concretions form in the urine, each of which doubtless represents a diathesis; the characters of which, however, are not so dis- tinctly marked, or so well recognized as those that have just been described. Cystine is one of the rarer forms of morbid product occasionally met with in the bladder. It differs from all other in- gredients, in containing a large quantity— about 26 per cent. — of sulphur. It is very rarely seen as a sediment in the urine, but when it occurs in this form it presents the Cystine. microscopic characters seen in fig 356, being composed of hexagonal laminae. Calculi con- taining cystine have occasionally been met with. Dr. G-olding Bird states in his work, that in Guy's Hospital Museum there are eleven composed of this peculiar STRUCTURE OF CALCULI. — RENAL CALCULI. 903 animal matter; and in the Museum of University College we have some good specimens. Cystine in calculus has a peculiar yellowish or greenish and waxy look, very different from any other ingredient met with in urinary concretions. Xanthine, uric, or xanthic oxide, was first noticed by Dr. Marcet, and has since been observed by Laugier, Langenbeck, and others. It is of extremely rare occurrence, and has only been found in a few recorded instances in the form of calculous concretions. These have generally been of small size, with the exception of the one removed by Langenbeck, which weighed 388 grains. For the chemical characters and constituents of this substance I must refer to Dr. Bird's work. Carbonate of lime has occasionally been met with as an amorphous powder in alkaline or very faintly acid urine. I am not aware of any calculus of this composition having ever been found, but Dr. Bird states that he has detected carbonate of lime as forming a distinct stratum in some phosphatic calculi. Structure of calculi.—Calculi, though sometimes composed throughout of the same deposit, are not unfrequently made up of layers or strata, differing in chemical composition from one another, and then usually go by the name of alternating calculi. Most frequently the nucleus consists of lithic acid or lithates; next in the order of frequency comes the oxalate of lime; and then the phosphatic nucleus. It is very seldom that the nucleus is absent; but concretions have occasionally been met with in which none could be detected, or in which it was even replaced by a cavity. The nucleus is usually as nearly as possible in the centre of the calculus, and is generally pretty regular in shape; occasionally, however, it is branched or curiously radiated, and then the concretion generally affects a corresponding outline. Calculi containing two or three nuclei have sometimes been found, consisting probably of an equal number of concretions agglomerated together. The body of a calculus having the uric acid nucleus is usually composed of some of the lithates; but not unfrequently these are incrusted by a deposit of phosphates. In other instances again, the body may be wholly composed of some of the earthy phosphates, which more rarely alternate with the oxalate of lime or the triple phosphates. An oxalate of lime nucleus usually has a body of the same constitution; but in some cases it is incrusted by phosphates or urates. When the nucleus is phosphatic, the concretion is always of the same constitution. Vesical calculi may be formed either in the kidneys or the bladder; those that contain a nucleus of the urates or oxalates are probably renal m their origin; whilst those that have a phosphatic nucleus are usually vesical from the first; renal nuclei being rarely met with of this composition. Renal calculi—When a stone forms in the pelvis of the kidney, it usually gives rise to pain in the loin. When of small size it may descend into the bladder with but little suffering to the patient; but, if large enough to irritate the ureter and to pass with some difficulty, it then gives rise to a peculiar train of symptoms that will immediately be described. In some cases the calculus attains a very large size, occupying the whole of the pelvis of the kidney, ex- tendino- into the calices and ureter, and being moulded, as it were, to the shape of the parts amongst which it lies; it then gives rise, by its pressure to absorp- tion of the substance of the kidney, and occasions, by the magnitude that it attains, excessive pain and irritation in this region, the patient usually eventu- ally chins, worn out by constant suffering, and the irritation of incurable kidney disease. In some instances, stone in this situation has been known to give rise to abscess in and around the kidney, and has even been discharged through an ^InThos: cts^n whichtrenal calculus descends into the bladder, the patient is seized with pain in the loin that has been the seat of previous irritation. ThTs pain is usLlly of the most agonizing character, extending into the cord 904 STONE IN THE BLADDER. and testis and down the thigh of the affected side. There is retraction of the testicle, with constipation and vomiting; frequently accompanied by the passage of scanty, high-colored, and bloody urine, and great constitutional disturbance. This pain usually continues of a somewhat remittent character, until the calculus enters the bladder, when, unless expelled, it gives rise to a peculiar train of symptoms, depending on its presence in that organ. During the descent of a renal calculus, which always occupies many hours, and perhaps some days, the patient should have full doses of opium adminis- tered, be put into a warm hip-bath, and have mustard poultices applied to the loin, or be cupped in this situation, if necessary; the bowels should also be thoroughly emptied by enemata. It is well to bear in mind that a somewhat similar train of symptoms to that induced by the descent of the calculus, may be excited by some forms of irritation or flatulent distension of the ccecum and descending colon, which will require appropriate treatment. Vesical calculi.—Though vesical calculi occasionally owe their origin to the descent of a stone from the kidney, yet it not unfrequently happens that there is no evidence of their coming from such a source, but every appearance of their being deposited in the bladder; a nucleus being originally formed in this viscus by the aggregation of some sabulous matters, around and upon which fresh deposits take place, until a true calculus is formed. In some instances, vesical calculi have been found deposited upon, and incrusting foreign bodies accidentally introduced into the bladder, such as a piece of straw, a pin, a bit of bougie, &c. The number of calculi in the bladder varies considerably; most commonly only one is encountered; but in about one-fifth or one-sixth of the cases ope- rated upon, several will be found: from two to six or eight are by no means uncommonly met with. Occasionally several dozens have been detected, and there are even instances on record in which some hundreds of distinct and separate calculi have been found in one bladder. The most remarkable case of this kind is one, in which Dr. Physick re- moved from a judge in the United States, upwards of a thou- sand calculi varying in size from a partridge-shot to a bean, and each marked with a black spot. Several calculi may become matted together in one large concretion, as in the annexed representation of a calculus that I removed last year from a . child (fig. 357), which is formed of eleven distinct lithic acid calculi soldered together in this way, besides which three others were lodged in the bladder. When there are several calculi in the bladder, the attrition of one against the other usually causes the opposing surfaces to become smooth, thus consti- tuting facets. In some cases, however, the calculi are numerous, and there are no signs of attrition. In a patient of mine who had fifteen calculi in his blad- der, all the stones were round, about the size and shape of marbles, without any signs of rubbing. Calculi have been occasionally known to undergo spontaneous rupture in the bladder, by a kind of concussion against one another, or, as Civiale supposes, by the contraction of a hypertrophied bladder, by which one stone may be broken into a number of fragments. In some instances these have agglome- rated together, by the deposit of a quantity of phosphatic matter upon and around them. In other instances the different fragments may each form the nucleus of a fresh calculus, so that the bladder may afterwards contain several concretions. The size of calculi varies from that of a hemp-seed or a pin's head to a con- cretion of immense magnitude. One of the largest with which I am acquainted is a calculus removed by the high operation by Dr. Uytterhoeven of Brussels, which I saw some time ago in his possession, and of which he has been obliging enough to give me a cast; it is of pyriform shape, and measures 16^ inches in VARIETIES AND CAUSES OF CALCULUS. 905 its longest circumference, and 12^ inches round at its broadest part, being 6^ inches long, and about 4 wide. In the celebrated case of Sir W. Ogilvie, Cline attempted, but failed, to extract a calculus measuring 16 inches round one axis and 14 round the other. It weighed 44 ounces, and must have been about the size of Dr. Uytterhoeven's. These enormous concretions are happily rarely met with, the usual size of stones removed by operation being from about one to two inches in the longest diameter, somewhat narrow, and perhaps flattened. The weight of calculi commonly varies from a few grains to several ounces; the commonest size is from three drachms to about an ounce or two in weight, occasionally from three to six; from this they may range upwards until several pounds are reached. Thus, in Cline's case the stone weighed 44 ounces, Des- champs saw one of 51 ounces, and Morand one weighing 6 lbs.: none of these admitted of removal. The largest calculi are usually composed of phosphates, in greater part if not in whole. The hardness of calculi varies considerably; the oxalate of lime is the hardest; the lithates come next in consistence, and are often very hard, though brittle; the phosphates are always comparatively soft and friable. The shape of calculi presents great variety; most commonly, however, they have an ovoid figure. Concretions of urate of ammonia and uric acid are gene- rally pretty regularly ovoidal, smooth, and disc-like. Those composed of oxa- late of lime are usually somewhat globular or square-shaped, and generally rough, nodulated, or spiculated upon the surface. The phosphatic calculi present usu- ally the most irregular outline; most commonly, it is true, they are ovoid or globular, but not unfrequently branched as if moulded to the interior of the kidney, constricted, or of an hour-glass shape. The cystine calculi are gene- rally tolerably oval and regular in outline. Most frequently calculi lie loose in the bladder; but occasionally they may be fixed in this viscus, owing either to their being encysted, and then lying in one of the sacculi that have already been described within the walls of the bladder (figs. 358 and 359), or by being fixed in and embraced by one of the ureters, and in other cases by being deposited upon, and partly included in fungous growths. Fio. 358. Fig. 359. Exterior of bladder containing an encysted cal- culus at a. Interior of the same bladder, showing small orifice leading into cyst at a, ureter b. The causes of calculi are somewhat obscure. There can be little doubt, it is true, that the different forms of concretion are connected with the varieties of diathesis that have already been described, and we may look upon the forma- tion of a calculus as an indication of the existence, in a greater degree of 906 STONE IN THE BLADDER. intensity than usual, of the same causes that, under ordinary circumstances, give rise to sediments or gravel; but why, in particular cases, the aggregation into a calculous mass takes place, it is impossible to say. Age appears to exer- cise considerable influence upon the production of calculi; for though stone may occur in the bladder at all periods of life, and even, according to Stahl, be congenital, it is certainly more frequent amongst children a few years old, and at advanced periods of life, than during middle age. Mr. Coulson has collected 2972 recorded cases of lithotomy from various sources; of these, 1466 occurred under the age of ten, 731 from eleven to twenty, 205 from twenty-one to thirty, 264 from thirty-one to fifty, and 306 from fifty-one and upwards. It would appear that in some parts of the world calculus is a far more com- mon disease than in others. It is generally more frequently met with in cold than in warm climates; indeed, in tropical countries I believe the disease is scarcely known. The Negro race also is remarkably exempt from this affection. It is a singular fact that in some parts of the same country calculous disorders are of far more frequent occurrence than in others. Thus it is well known that the inhabitants of the east coast of England and Scotland are peculiarly liable to these disorders, and that in Norfolk, stone occurs with especial frequency; this district furnishing, in all probability, as many cases as the half of the rest of England. In America also, it would appear that the inhabitants of certain states are peculiarly obnoxious to this affection; and I understand that in some districts of Germany the disease may be said to be almost unknown, whilst in others it is of common occurrence. To what these differences are owing it is impossible to say. Peculiarity of race, of constitution, and of diet, with exposure to prevalent easterly winds, have all been assigned as reasons for them, but probably not on very sufficient grounds. Sex influences materially the occurrence of stone, which is far more frequent in the male than in the female. The symptoms of stone in the bladder vary somewhat according as the cal- culus lies loose in the cavity of the viscus or is encysted. They also vary con- siderably according to the size and shape of the stone, the condition of the bladder, and the constitution of the patient. Most commonly the severity of the symptoms are in proportion to the magnitude of the calculus. This, how- ever, is not always the case. In a patient whom I recently cut, the most intense suffering and repeated attacks of cystitis had been occasioned by a small but sharp-pointed calculus, not weighing more than gj ; and some years ago I saw a patient in whose bladder five calculi were found after death, nearly as large as chestnuts, though their presence had never been suspected during life by the different surgeons under whose care he had been for stricture, so little distress had they occasioned. In some cases the symptoms of stone very suddenly declare themselves, and then the surgeon finds on examination that the patient has a largish calculus, which must have been a long time forming without attract- ing attention. Rough calculi usually give rise to more severe symptoms than smooth ones, owing to their inducing a chronic form of cystitis; and, as the constitution is usually a good deal shattered and the nervous system very irri- table in those conditions of the system in which the phosphates are deposited, phosphatic calculi are usually attended by more suffering and constitutional dis- turbance than other forms of the disease. The symptoms induced by stone may be divided into the rational and physi- cal. The rational signs, consisting of pain, increased frequency in micturition, the occasional stoppage of the urine, and various morbid conditions of that fluid. The physical signs are those by which alone the surgeon can positively deter- mine the presence of the calculus, feeling it with the sound. The pain in calculus is usually the first symptom that attracts attention; it is not only experienced in the region of the bladder and the perineum, but radiates widely in the course of the sacro-lumbar nerves. The patient complains SYMPTOMS OF CALCULUS. 907 of a heavy and dragging sensation in the groins, extending down the outside or back of the thighs, and not uncommonly experienced in the soles of the feet. The penis likewise is the seat of a good deal of uneasiness, frequently of a sharp and cutting pain in the glans. This is especially noticed in children, in whom attention is often attracted to the complaint by their constantly squeezing and pulling the organ to relieve the distress they suffer in it. The pain is much increased by any movement by which the stone is jolted about in the bladder, as in driving, riding, or jumping; and is especially severe in those cases in which cystitis occurs. It is always most severe towards the termination of, or immediately after micturition, as there is then a tendency for the calculus to roll forwards towards the neck of the bladder, where it comes in contact with and is grasped by the most sensitive part of that organ. Hence it is not unfre- quent in cases of calculus occurring in children to find that the little patient instinctively lies upon its back or side whilst making water, and thus escapes much of the agony that it would otherwise suffer. In adults in whom the pros- tate happens to be enlarged, the calculus usually lies in a depression behind this gland, and hence, being prevented coming in contact with the neck of the bladder, occasions less suffering than in other cases. An occasional stoppage commonly occurs in the flow of urine before the bladder is emptied, owing to the stone being impelled against its neck, and thus block- ing up the urethra; but on the patient lying on his back or on his side the stream flows again, the situation of the calculus being changed. In consequence of the irritation set up in the bladder occasioning chronic inflammatory action of the mucous membrane, there is an increased frequency of micturition. The urine is passed in small quantities, and usually contains some mucus or pus, and is occasionally tinged with blood. The occurrence of blood in the urine of children leads strongly to the suspicion of stone, and should always induce the surgeon to make an examination of the bladder with the sound. If the kidneys are irritated, the urine is commonly albuminous. As a result of the straining and general irritation about the genito-urinary organs, prolapsus of the anus, accompanied by tenesmus, is by no means uncom- mon, and in some cases there is very troublesome priapism. When a stone is encysted, those symptoms that depend upon its being loose and rolling about in the bladder, are necessarily absent; thus there is no stop- page in the water, the urine is seldom bloody, and the pain is not materially increased by jolts and rough movements, though there is weight and pain in the usual situations, and increased frequency of micturition from the pressure and irritation of the calculus. The existence of stone is FlG- 36°- finally determined by sound- ing the bladder. A sound is a solid steel instrument shaped like a catheter, but shorter in the curve, so that it may ex- plore more thoroughly all parts of the bladder, espe- cially those behind the pros- tate. It should also have rather a wide and smooth steel handle. The operation of sounding should be con- ducted as follows : — The 908 STONE IN THE BLADDER. to contain three or four ounces of urine. The surgeon then using his left hand, or crossing over to the patient's right side, whichever he finds most convenient, carefully directs the beak of the instrument towards the back of the bladder, turning it from right to left over the whole of that region (fig. 360); he next draws it forwards on one side as far as the neck, tapping as it were gently with its beak; he repeats the same manoeuvre on the other side, and lastly directs the end of the instrument by raising its handle into the lower fundus, which he carefully explores. Should he not detect the calculus in any of these situations, he depresses the handle between the thighs, and tilts up the beak so as to examine the subpubic portion of the organ (fig. 361). Fig. 361. In the event of his not meeting with a stone, he may direct the patient to stand up, and then explore the bladder, first upon one side, then on the other. Should the rational signs of stone be well marked, though no calculus be struck, the surgeon must not give a decided opinion in the negative after the first exploration, but should examine the patient again a few days later, with the bladder in dif- ferent states as to its contents. In making this second examination, I have found it of great service to use a hollow steel sound, by which the organ can be injected or emptied at pleasure (fig. 362). The patient should on this occasion have his bladder injected through such an instrument as this, with four or six ounces of tepid water, so as to dis- tend the organ slightly, and prevent the folds of mucous membrane overlapping any concretion that may exist in it. Its interior is then carefully explored in Fia. 362. the way already described, and if the stone cannot then be detected, the con- tents of the bladder are gradually allowed to escape through the sound, and the patient desired to stand up whilst the exploration is being proceeded with. In this way, by examining a patient in different positions and in different con- ditions of the bladder as to capacity, a calculus is sure to be detected if one exist. A lithotrite may occasionally be advantageously used as a sound for the detection of small calculi lying behind the prostate, a situation more readily reached by its short beak than by an instrument of larger curve. These exami- nations must not, however, be too protracted; the time occupied should not exceed above five minutes, lest cystitis be induced. When a stone is struck by the sound, there is not only a characteristic and distinct shock communicated to the instrument, but there is a tolerably loud click heard, which can be detected by the by-standers, and frequently by the patient as well as by the surgeon. By conducting the sounding properly, the surgeon may usually ascertain not only the existence of a stone, but its size, and hardness; whether it is single, if it be encysted, and the general state of the bladder, all of which it is of im- SOUNDING FOR STONE. 909 portance that he should be acquainted with before undertaking any operation. A good deal of this information may be elicited by the ordinary sound, but some of the points can only be accurately determined by sounding with the lithotrite. The hardness of the stone may usually be judged of by the more or less clear ringing character of the click; a lithic acid or oxalate of lime calculus giving a sharper sound than a phosphatic concretion. A calculus may generally be known to be encysted if the sound strikes it at times, but not at others (fig. 363); if the stone always appears to be fixed in Fio. 363. one situation; and if the beak of the instrument cannot be made to pass round it, so as to isolate it, but feels a kind of tumor projecting through the walls of the bladder, around or on one side of the point where the calculus is struck. The fasciculated, roughened, and sacculated condition of the bladder may generally be detected by the way in which the beak of the instrument grates and rubs over the organ. The size of the calculus is best determined by a lithotrite. It is true that a surgeon may sometimes come to a decision as to the bulk of a calculus by ob- serving the extent of surface along which the sound is in contact with the stone as the instrument is being withdrawn. But a very rough guess only can be arrived at in this way, and I have frequently seen very experienced surgeons deceived in their estimate of the size of a calculus, mistaking perhaps several small ones lying together for one large one. By introducing a lithotrite and seizing the calculus gently between its blades, a correct estimate of its size may always be arrived at. In order to determine that several calculi exist in the bladder it is sometimes sufficient for the surgeon to feel that the beak of the sound comes in contact with a stone on either side of the organ, or that it can be distinctly insinuated between two concretions. In some cases, however, these points cannot clearly be made out; and then the surgeon introducing a lithotrite and seizing the first calculus that he meets with should hold this between the blades of the instru- ment, and whilst it is so fixed move it and the lithotrite from side to side, when, if a click is heard and felt, he may be sure of the existence of another S Errors occasionally occur in sounding; the surgeon mistaking a hardened and fasciculated bladder, having its ridges perhaps incrusted with sabulous matter, for a calculus; this is especially apt to happen in children. In thesepeases, however, the mistake may usually be guarded against by the absence of a dis- tinct click, though a rough grating sensation be experienced, and by the sur- geon being unable to isolate a stone. Yet the difficulty in some cases is great; Velpeau states that he is acquainted with four instances, and S. Cooper with 910 STONE IN THE BLADDER. seven, in which patients have been cut and no calculus found; and when we reflect that these accidents have happened to such men as Cheselden, who on three occasions cut a patient and found no stone; to Crosse, to Roux, and to Dupuytren, it is easy to understand that in some cases the difficulty of coming to a correct decision must be very great. In women the symptoms of stone closely resemble those met with in men, and the detection of the calculus is usually very easy, owing to the shortness of the canal and the facility with which the stone may be tilted up by introducing the fingers of the left hand into the vagina. The sound used in these cases should be shorter and less curved than that employed for the detection of calculus in the male bladder. After a stone has existed for some time in the bladder it induces serious pathological changes in the whole of the urinary apparatus. The urethra usually becomes slightly dilated, and the prostate not unfrequently somewhat enlarged and irritable, in consequence of which a kind of pouch is formed behind it, in which the calculus is apt to lodge. The most important changes, however, take place in the bladder and kidneys. The bladder becomes extremely sensitive, especially about its neck, and is consequently unable to contain as much urine as usual; hence it becomes contracted. In some rare instances, however, as will be more especially noticed when we come to speak of lithotrity, it falls into an atonic condition, and then is apt to become rather largely dilated. The mucous membrane is commonly a good deal inflamed and irritated by the pre- sence of the calculus, and the muscular coat becomes thickened and hypertro- phied, so as to give it a very fasciculated or columnated appearance. Cysts occasionally form containing sabulous matter and fetid pus or urine, and in some cases lodging a concretion, which then constitutes an encysted calculus lying altogether outside the cavity of the bladder, with which it merely communicates by a very narrow aperture, as in figs. 358 and 359, representing a case that was under my care some years ago, and which is fully described in the Journals for March, 1853. The kidneys are usually irritated, often congested, frequently in a state of granular degeneration, and ultimately become the seat of such struc- tural changes as are incompatible with life. When death occurs as the conse- quence of stone, the patient usually sinks, worn out by protracted suffering and kidney disease. OPERATIONS FOR THE REMOVAL OF STONE FROM THE BLADDER. _ Calculus may be removed from the bladder by two distinct operations. By lithotomy, or the cutting operation; and lithotrity, or the crushing one. We shall first consider lithotomy, as the more ancient, and perhaps even yet the more common, operation of the two. It is not my intention to enter into the general history of lithotomy—an operation that has been practised from the earliest ages; and a sketch of the gradual modifications of which, that have at various times been introduced, from the rude attempts of the Greek and Roman surgeons to the barbarous and unscientific procedures adopted by the itinerant operators after the revival of letters, would occupy much space and be attended by but little advantage. For all this I would refer the reader to the classical works of Deschamps and of John Bell. The operation, as now generally practised in this country, is essen- tially that introduced by Cheselden, and modified more or less according to the peculiar views of particular surgeons. Hence there are a variety of ways in which it is performed, though surgeons generally are agreed upon the great principles involved in it. It is in carrying these out that they differ — as in the direction and extent of the incisions, and in the instruments employed, which have been much varied to suit the taste of particular operators. This detail would be foreign to this scope of the work: I shall, therefore, in a great LATERAL OPERATION OF LITHOTOMY. 911 measure confine myself to the description of that particular modification of Cheselden's, or the lateral operation introduced by the late Mr. Liston, most skilfully practised by him, and now very generally adopted by most of the best surgeons of the day in this country. Before subjecting a patient to operation, his general health must be properly attended to; and, indeed, if we find the constitution much broken by prolonged suffering, the bladder or kidneys seriously diseased, as indicated by the exist- ence of pus or albumen in his urine in large quantity, it will be wise to postpone the operation for a time, or perhaps even to defer it altogether. Supposing, however, that the stone is of moderate size, that the patient's health is in a pretty good state, that the urine is either healthy or contains but a moderate quantity of pus or albumen, and that there is no visceral complication to prevent the performance of the operation, it will only be necessary to subject him to proper preparative treatment for a short time, so as to allay or remove irritabi- lity of the urinary organs, before proceeding with it. With this view, he should be kept as quiet as possible for about a week or ten days preceding the opera- tion ; his diet should be properly regulated, but not be of too low a kind; pain lessened by the administration of opiates or henbane, and the bowels properly relieved. On the day preceding the operation, a dose of castor-oil or some other aperient should be administered; and, on the morning of the operation, the rectum must be emptied by means of an enema. LATERAL OPERATION OF LITHOTOMY. The surgeon must see that the table is firm and of a convenient height, so that, when he sits on rather a low stool, the patient's nates will be on a level with his breast; a few blankets doubled should be laid upon the table, covered by a piece of tarpaulin hanging over the end, and a tray of sand placed under it on the floor. The instruments necessary are the following: a pair of lithot- omy tapes, a sharp and a probe-pointed scalpel, a staff, forceps, and scoops of various sizes, and a tube. To these may be added a searcher, and a brass injecting syringe. The tapes should be of coarse flannel, about three yards long, by three inches broad. The scalpel for the adult may be of the size and the shape represented (fig. 364); for children it may be made proportionately small. A probe-pointed Fig. 364. Fig. 365. c— lithotomy-knife should also be at hand, of the size and shape here represented (fig. 365). ., . . The staff should have a deep groove on its left side, occupying nearly one- third of the instrument; it should be well curved, of as large a size as the urethra will admit, and have a roughened handle (fig. 370). The forceps must not be too heavy, but should be of a good length in the handles, and have the joint well set back; the inside of the blades, as recom- 912 STONE IN THE BLADDER. mended by Mr. Liston, should be lined with linen, to prevent the stone slipping (fig. 366). Mr. Coxeter has lately made them with open blades, but lined with linen as heretofore (fig. 372); in this way, as there is less metal, the weight is Fig. 366. Fig. 367. Fig. 368. Fig. 369. Fig. 370. Fig. 371. iWJ diminished, and the diameter of the instrument with a stone in its grasp is materially lessened. The ordinary forceps are straight, but it is advantageous to be provided with some that are curved (fig. 367). The handles should be made with a loop on one side and a ring on the other; the ring Fia. 372. for the reception of the thumb should be placed somewhat obliquely. The scoops of different sizes, and curved, can most conveniently be used when fixed in a roughened handle (figs. 368 and 369). The tube should be of gum-elastic, well rounded at the end, and provided with silver rings. The searcher is a slightly curved sound having a bulbous extremity (fig. 371). The syringe presents nothing peculiar. In describing the operation of lithotomy, we shall first of all consider the different steps seriatim of an operation that presents no unusual complication or difficulty; we shall then consider the difficulties that may be met with during the operation, the accidents that may occur, the principal sources of danger, and the causes of death. Ordinary lateral operation.—The patient should be desired to hold his water for two or three hours before the operation, but if he has not done so, and the bladder is empty, it must be injected with about six ounces of tepid water, in order to steady it and to facilitate the seizure and extraction of the stone. After chloroform has been administered, the surgeon should introduce a full-sized staff, which he uses as a sound, in order to feel for the calculus If he detects it, he proceeds with the operation; if he cannot detect it, it is usually recommended that he should withdraw the staff and introduce a sound, with which he examines the bladder, and in the event of his still failing to discover its presence, the operation must be deferred, for it is an imperative rule in surgery that lithotomy should never be performed unless the stone can be felt at the time that the patient is actually on the table. It is, however, safer not to proceed with the operation unless the stone can be LATERAL OPERATION OF LITHOTOMY. 913 felt with the staff^lest the point of this, though apparently in the bladder, be actually engaged in a false passage. The patient is then to be firmly tied up and brought to the end of the table, so that his nates project beyond it, where he is to be securely held by an assistant on either side, who grasps the foot in his hand, places the patient's knee under his arm, and draws the limbs well aside, so that the perineum may be fairly exposed. It is desirable that the perineum be thus fully exposed to the surgeon. In a patient, however, on whom I once operated, this could not be done, owing to the left hip being stiffened by chronic rheumatic arthritis; but I did not experience any particular difficulty in the operation, though somewhat inconvenienced by the position of the limb. The surgeon then seating himself before the patient, shaves the perineum — if this have not already been done — and introduces his finger into the rectum to see that the gut is empty. He then gives the staff in charge of a trusty assist- ant, who stands on the patient's left, and who raises and draws aside the scro- tum with the left hand whilst he holds the staff in the right (fig. 373). The surgeon then sees that the staff is held in the way in which he prefers it. There are two ways in which it may be held; it may either be drawn well up into the arch of the pubes, or it may be pushed somewhat down, and slightly turned towards the left of the perineum. Liston always employed the first method, which I certainly think is the best, as it tends to increase the space between the urethra and the rectum, and consequently lessens the danger of wounding that gut, which more than counterbalances the advantage of the other method — that of approaching the membranous portion of the urethra to the surface. The external incision is made by entering the knife in the raphe of the peri- neum one inch and a half above the anus, and carrying it downwards and out- wards until it reaches a point that is just below the anus, but Fia. 373. about one-third nearer to the tuberosity of the ischium than to the margin of the anal aper- ture (fig. 373). It is useless to prolong the incision beyond this, as any freer division of the structures of the scrotum and on the nates cannot facilitate the extraction of the stone; but it must occupy the extent indi- cated, otherwise considerable difficulty may be experienced in the later steps of the operation. The depth to which this incision should be carried must vary according to the obesity of the subject, usually from about three- quarters of an inch to an inch. By this incision the skin, superficial fascia, and subcutaneous fat are divided. After it is completed, the knife is introduced again towards the upper part of the wound, and the blade run lightly down- wards over any resisting structures, the left fore-finger being placed at the middle of the wound so as to protect the rectum. In this way the transversalis perinei muscle is divided together with some cellular tissue and small vessels, and the triangular space is opened between the accelerator unnae and erector penis muscles; the knife is then withdrawn, and the left index finger pushed deeply into this space until the edge of the nail is lodged in the groove of the staff (fio-. 374), which can be felt just anterior to the prostate, thinly covered by the membranous portion of the urethra. The point of the knife is then 58 914 STONE IN THE BLADDER. pushed through the urethra at its membranous part into the groove of the staff, above the index finger, which protects and presses to the right, the rectum lying beneath it (fig. 375). When the knife is felt to be well lodged in the groove, its handle is slightly depressed so that the point Fig. 374. may be raised, at the same time the blade should be somewhat lateralized, so that its side lies parallel to the ramus of the ischium. If the edge is turned too directly downwards towards the mesial line the rectum may be wounded, and if directed too much outwards the internal pudic artery will be endan- gered (fig. 377); hence the mid course is the proper one. The surgeon keeping the knife steadily in this position and pressing the point firmly against the side of the groove of the staff, which he must never for a moment lose, pushes it forwards through the deep perineal fascia, a few fibres of the levator ani, and the prostate, and thus makes an entry into the bladder (fig. 376); he then withdraws the knife by keeping its back against the staff so as not to enlarge the extent of the incision in the prostate. Through this, and along the staff, he then pushes his left index finger until it reaches the bladder, when he endeavors to feel the calculus with its tip. Should his finger be short, the perineum deep, or the pros- tate enlarged, he may be unable to reach the bladder in this way; and must then introduce a blunt gorget, as recommended by Cheselden and Martineau, in order to dilate the aperture in the prostate. K he uses his finger for this purpose, he gives it a twist or two after passing it through the prostate so as to expand and dilate the aperture through which it is entered. Having made sure that it is in the bladder, and having felt the stone, he directs the assistant to withdraw the staff from the urethra. Here let us pause and examine the principal points in this the first and second stages of the operation. It will be observed, that in accordance with the best authorities upon the subject, and with my own experience, I have recom- mended the external incision to be free, the rectum to be protected by the left index finger, and the knife to be somewhat lateralized during and after the opening of the urethra. 1st. The position of the knife must be carefully attended to, especially during the deep or second incision. At this stage of the operation the edge should be lateralized, that is, directed about midway between the horizontal and perpen- Fig. 375. LATERAL OPERATION OF LITHOTOMY. 915 dicular position, so that the surface of the blade lies nearly parallel to the ramus of the ischium. The manner of holding the knife has been much discussed, Fia. 376. and necessarily and naturally varies with different surgeons. I believe it signi- fies little how the handle of the instrument is held between the surgeon's Fig. 377. Fig. 378. fino-ers provided the edge is never turned upwards, but is always kept well lateralized, and the point steadily pressed into the groove of the staff. 916 STONE IN THE BLADDER. Provided a surgeon knows what he is about, he may safely hold his knife as best suits his own convenience. In the first Fig. 379. incision, most operators, I believe, hold the knife under the hand, as represented in fit:. 379, a position that that excellent lithotomist and accomplished surgeon, Mr. Fergusson, preserves throughout the operation. Mr. Liston, in the early part of his career, appears to have held the knife, in the second stage of the operation, above the hand; and in all the representations, published as well as unpublished, that he has left of his operation, has depicted the knife and hands in the position as shown (fig. 380), which, in the last edition of his Practical Surgery, he describes as a correct sketch of " the position of the hands and knife" at the commencement of the second stage of Fig. 380. the operation. There can be no doubt, however, as Mr. Fergusson has pointed out, that in actual practice, at least after his first few years as an operator, he held the knife under the hand with the index finger upon the side or the back of the blade. For my own part, I believe that every surgeon will hold the knife in the way which he finds most convenient, and as it were natural to him. If any rules are to be laid down on this point, I should say, that when operating on a child, or on an adult with a shallow perineum, the knife is most conveniently held as represented in fig. 379. But if the patient be fat and the perineum deep, then 1 think that it is a question whether greater steadiness may not sometimes be secured by holding the knife somewhat in the manner of a gorget, with the index finger, perhaps, a little more upon the side of the handle (figs. 376 and 381); Fig. 381. in this way the point is firmly pressed into the groove of the staff, _^J^v out of which it cannot slip, as it is """ v^^ ^'^F>r!l*«%Sl' secured and supported by the index "■"^ -k"~* --j t , mi.......'■"'——fr^1- >^ finger being somewhat under it. k^ i „^k_^ "^^e sect*on 0I> *he prostate is thus *i!ij|«gj|p*ifc""*^ made by a steady push or thrust J of the knife forwards, and not by any cutting movement downwards. No danger can result in the deep incision from pushing the point of the knife up into the groove of the staff; but there is great risk of missing the bladder, and getting into the recto-vesical space, if it be at all depressed and the handle raised, though this cannot always be avoided if the staff be pushed deeply into the bladder. 2d. The incision into the prostate should be of very limited extent: on this point all surgeons, I believe, of the present day are agreed. Scarpa advises that the incision into it should not exceed 5 lines in adults and 2 in children. It is difficult to measure the extent of the incision: it is sufficient to say, that it should be as limited as possible; and if care be taken to push the knife in, with the point well pressed against the groove, and the blade forming but a limited angle with the shaft of the staff, and especially in withdrawing it that it be brought carefully back over the finger and still in contact with the instru- LATERAL OPERATION OF LITHOTOMY. 917 ment, there will be no danger in cutting too widely, or in doing more than merely notching the apex of the prostate (fig. 378, a). The danger, however, it must be borne in mind, does not consist in the section of the gland itself,__ which is in reality a structure of but little importance,—but in cutting beyond it into the reflections of the pelvic fasciae, which will be opened up if the base of the prostate be cut, and the wound of which will, almost to a certainty, be followed by urinary infiltration and diffuse inflammation. In the section of the prostate then, two points have specially to be attended to: one is, that the knife in entering be not pushed forwards at too great an angle with the staff, so as to cut widely; and the other is, that in its with- drawal the blade be kept steadily in contact with the staff; indeed, I believe there is more danger of doing mischief in the withdrawal than in the entry of the knife, for if it leave the staff for a moment all guide is lost and the edge may sweep downwards through the base of the prostate and its investing cap- sule. As the knife is withdrawn, the left index finger is pushed forwards into the aperture in the prostate, which is then dilated by its pressure to a sufficient extent for the introduction of the forceps, which are slipped in as the finger is withdrawn, and the extraction of the stone. This part of the operation may very conveniently be performed, as was usually done by Mr. Liston, at the moment the surgeon is stooping down, engaged in selecting his forceps. It is readily effected; for the prostate, though dense, is friable, and breaks down easily under somewhat forcible pressure by the finger. In this way, by a mere notching of the prostate, — by a slight section of its apex or urethral surface, followed by simple dilatation with the finger, — sufficient space will be obtained for the extraction of all moderate-sized calculi, without the employment of any violence, or the infliction of any bruising upon the tissues. [In the performance of the lateral operation for lithotomy Dr. Pancoast, of Philadelphia, has for many years been in the habit of dividing the prostate gland and neck of the bladder by a manoeuvre of a different character from that described in the text. The staff employed by Dr. Pancoast in his operation, is one of considerable curve, and is held by an assistant so that the convexity of the instrument shall bulge somewhat forward in the perineum. The knife which he prefers is an ordinary scalpel slightly concave on the back. This is made to reach the groove by the usual incision, and the blade being lateralized, is held like a gorget, with its point in the groove of the staff. The operator then takes the handle of the staff in his left hand, and as he brings it down, carries by the same motion the blade of the knife and the curved portion of the staff upwards in the direction of the longitudinal axis of the bladder. The edge of the knife in its transit will thus effect the necessary division of the prostate gland. The peculiarity of this manoeuvre depends upon the fact, that the position of the knife with regard to the staff, is not changed during the execution of the process just described. The point of the blade held fixed in position enters the cavity of the bladder synchronously with the curve of the staff against which it rests; and it is not thrust forwards along the groove of the latter, according to the usual custom. ^ _ The advantages possessed by this procedure are, in the estimation of Vr. .Fan- coast, the facility and quickness with which it is performed^ the diminished risk of injury to the rectum, and the comparatively limited division of the pro- state gland. In consequence also of the upward movement of the knrie, an absolute degree of immunity is afforded to the base of the bladder so fre- quently wounded by the horizontal thrust" of the instrument through the pro- state gland, which, it must be remembered, is often depressed by the staff, nearly to the level of the lower fundus. . In the opinion of Dr. Pancoast there is also much less risk of hemorrhage as the circular movement of the knife divides to a less extent, the vascular and 918 STONE IN THE BLADDER. dilatable parts anterior to the prostate, for the protection of which the angular knife of Blizard was devised.] But another obstacle exists which will prevent the dilatation of the neck of the bladder to any very material extent, without an amount of bruising, or laceration, or even rupture that would probably prove fatal to the patient. This obstacle consists of a tissue, which has been described by Mr. Tyrrell as " an elastic ring" surrounding the neck of the bladder; by Mr. Liston, as " a fibrous or ligamentous band surrounding the orifice of the bladder, into which the muscular fibres of the organ are inserted." If this band be ruptured, either by the finger or by the expansion of the forceps, fatal consequences will ensue; but if it be divided, the other tissues, as Mr. Liston observes, will yield to an inconceivable extent, without injury to the ilio-vesical fascia. In thus describing the mode of incising the prostate and neck of the bladder, I have, generally, used the term " dilatation;" and I believe, that by a simple pro- cess of dilatation or expansion of these parts, and without any violence what- ever, small calculi of or under an inch in diameter may be extracted. In fact, for the removal of such stones, no force whatever is required, either in opening up the prostate or in withdrawing the calculus. But in removing stones of greater magnitude than this, I believe that the process of expansion of the pro- state and neck of the bladder, whether effected by the finger, a blunt gorget, or the opening up of the blades of the forceps, is a process of laceration rather than of dilatation, as I have frequently had occasion to observe in experiments on this point made on the dead subject. This laceration is, however, confined to the substance of the prostate, and does not extend through its capsule, or into the fasciae of the pelvis, without the employment of an extreme degree of violence, which would probably prove fatal. 3d. The next stage of the operation consists in the extraction of the stone. A pair of forceps of sufficient length and size, proportioned to that of the cal- culus, and previously warmed by immersion in tepid water, must be slid along the index finger, which is kept in the wound, and by which the neck of the bladder should be drawn somewhat down so as to meet the instrument. In this way, also, the stone may often be fixed by the point of the finger, and its posi- tion thus accurately determined. The forceps having been introduced closed, the finger is withdrawn, when a gush of urine will usually take place through the wound, if that fluid have not already escaped at the time that the incision is made through the pro- Btate. By this gush the calculus may, as Mr. Fergusson observes, sometimes be carried into the grasp of the instrument; most com- monly, however, the stone requires to be felt for with the closed for- ceps. When its posi- tion has been ascer- tained, usually at the inferior fundus, the blades are opened, and by pushing one against the wall of the bladder and giving it a slight shake,the calculus gene- rally drops between them, though occasionally it is somewhat troublesome to seize, and this indeed often constitutes the most tedious and annoying part of LATERAL OPERATION OF LITHOTOMY. 919 the operation. The forceps having the stone in their grasp are then closed and the stone drawn downwards through the wound. If it be small, it may be extracted at once without any difficulty; if of moderate size, the finger should be introduced along the blades, in order to feel whether it is in a proper posi- tion for extraction. If its long axis lie across the wound, this must be changed, and it must then be withdrawn by a kind of to and fro movement in the direction of Fig. 383. the axis of the pelvis (fig. 382). Should the stone be broken, or should there be several small calculi, they may generally be best removed by means of the scoop (fig. 383). In the event of fracture occurring, ^gRaT^ it would be necessary to wash out the bladder with tepid water, injected by means of a brass syringe, through a tube introduced by the wound. In children, and indeed in most cases in which the perineum is not very deep, so that after the introduction of the finger the stone can be felt and hooked forwards, the scoop is a most convenient instrument for its extraction, and in these cases I usually employ it in preference to the forceps. After the calculus has been removed it must be examined for facets, or the interior of the bladder explored by means of a searcher; and if other stones be found they must be dealt with in the same way as the first. The gum-elastic tube may then be introduced, and secured with tapes to a band round the patient's abdomen. This tube must be kept free from coagula by the introduction into it, from time to time, of the feather of a pen. By means of this tube a ready outlet is given to the urine, and the chance of infil- tration is lessened. The patient must then be removed to a bed, which should be properly ar- ranged by having a large square of Macintosh cloth put across it. On this a folded sheet should be laid, which must be rolled up on the further side so that as it becomes wetted by the escape of urine, it may be drawn across from under the patient. This must be changed frequently in order to keep him clean and dry. A full dose of tincture of opium in barley water should then be given; a warm flannel laid across the abdomen; plenty of barley or gum water allowed for drink, and nothing but rice-milk or light pudding for diet during the first three or four days. After this some broth may be allowed, and the quality of the food gradually increased. Occasionally, however, it may be necessary to depart from this rule. I have, indeed, on several occasions found it necessary to depart from the routine system of dieting the patient after lithotomy, and have with great advantage allowed wine, and even brandy, a day or two after the operation. In an old man, on whom I recently operated at the hospital, there was so great a tendency to depression, that it became necessary to ad- minister the brandy-and-egg mixture freely from the first, and to this I believe he owed his good recovery. At the end of thirty-six or forty-eight hours the tube may be removed, the sides of the incision by that time having become glazed over, and little danger of infiltration existing. The water continues to flow entirely through the wound for the first four or five days. About this time it frequently suddenly ceases to do so, escaping by the urethra. This is owing to the prostate be- coming turgid by inflammatory action, and thus blocking up the aperturein it; but as this swelling goes down, in the course of a day or two, the urine usually escapes by the wound again, and continues to do so in gradually de- creasino- quantities until the aperture is finally closed, which usually happens at about the end of fourteen or eighteen days; though in patients who suffer from phosphatic calculus it sometimes takes a longer period, owing to the broken state of the general health. After the operation appropriate constitutional 920 STONE IN THE BLADDER. treatment should be continued for some time in order to prevent a recurrence of the disease. Lithotomy in children is performed much in the same way as in the male adult; though it is worthy of note that the urethra will commonly be found larger than might be expected from the age of the child, readily admitting a No. 8 or 9 staff. The perineum also is usually proportionately more vascular in consequence of the irritation and straining. The most important point, however, is, that in the child the bladder lies high, being rather in the abdomen than in the pelvis; hence, it is of importance to raise the point of the knife somewhat more than in the adult in making the deep incision, and to be careful that it does not slip into the recto-vesical space, which may happen unless this precaution is taken. I have known this occur in several instances to hospital surgeons; the forceps being passed into this space under the supposition of its being the bladder, and in every case the patient died unrelieved. This accident is the more likely to happen, because in children the parts are very yielding, and readily admit of being pushed before the knife or finger, and the finger may thus pass between the neck of the bladder and the pubes, or into the loose cellular tissue of the recto-vesical space. The urethra being opened urine escapes, and the surgeon gets his finger into a distinct cavity, which he believes to be the interior of the bladder, but which is not so, but the recto-vesical space. DIFFICULTIES DURING AND DANGERS AFTER LITHOTOMY. The difficulties during the operation are two-fold; — getting into the bladder, and extracting the calculus. The difficulty of getting into the bladder is rarely experienced. It may, how- ever, arise in consequence of the surgeon neglecting to keep the point of the knife well lodged in the groove of the staff, and thus letting it slip into the recto-vesical space, the tissue of which being broken up, leaves a kind of cavity that he mistakes for the interior of the bladder. If the perineum is very deep and the prostate enlarged, he may also experience some difficulty in reaching the bladder, but he can scarcely fail to do so if he push the knife well on in the groove of the staff, and dilate the incision in the prostate with a blunt gorget, if his finger fail to reach the cavity beyond it. If, after the groove in the staff has been exposed, care is not taken to insin- uate, as it were, the nail into the opening in the urethra thus made, the mem- branous portion may be torn across, and the neck of the bladder may easily be pushed away from the surface, receding before the finger, the surgeon failing in reaching its cavity. When the road is once lost in this way, there is the very greatest difficulty in finding it again. The course that should be pursued is, I think, as follows: If the staff has not been withdrawn, the surgeon must again place the knife in its groove, and carefully push it on towards the neck of the bladder, notching that structure and passing the finger cautiously along the groove, and hooking down, as it were, the parts with his nail until he reach the inside of the bladder. Should the staff have been withdrawn, the surgeon must endeavor to pass it again; if he succeed in this, he may act as just stated; but if he cannot succeed in introducing the staff fairly into the bladder, he must, on no account whatever, endeavor to open that viscus, or continue his attempts at the extraction of the calculus, but should at once abandon the operation until the parts have healed, and then repeat it. The great danger in these cases arises from the surgeon losing his presence of mind, and endeavoring to enter the bladder without a guide, a procedure that must be unsuccessful, and can only end in the destruction of the patient. In adults, the difficulty is to get out the stone; in children, to get into the bladder. Difficulty in seizing the stone not unfrequently occurs. This is likely to DIFFICULTIES IN LITHOTOMY. 921 happen in all those cases in which, whether from the depth at which the bladder is from the surface, or the peculiar position of the calculus, the stone cannot be felt with the finger after the incisions have been made into the neck of the bladder. This is especially apt to happen if the patient is old and fat, and has a deep perineum, with perhaps some enlargement of the prostate, which consti- tutes the greatest difficulty in this respect, the calculus resting behind it in the deep fundus of the bladder. In such cases as these, long and curved forceps should be used. So, also, if the stone is very round, it is usually more difficult to seize than when flat or elongated. Flat, disc-shaped calculi, however, occa- sionally fall into the fundus of the bladder behind the prostate, and then cannot be readily reached by the forceps, which pass over them. Under these circum- stances they are best extracted by the curved scoop. Difficulty in extracting the calculus is far more frequently met with than in reaching the bladder. This may be owing to a variety of causes. The position of the stone may be such that it can scarcely be reached with the forceps; thus, when it is situated in the upper fundus of the bladder above the pubes, it is altogether out of the axis of the incision, and in such a case can only be extracted with great difficulty. Key recommends that in such cases the abdomen should be compressed, and thus the calculus pushed down into reach. This suggestion is a very useful one; and it was only by employing this manoeuvre, and using a very curved scoop, that I could remove a calculus lodged above the pubes, in a patient whom I cut at the hospital some years ago. The calculus may be lodged in the lower fundus, behind an enlarged pros- tate. Here the best plan is to use a much-curved pair of forceps, and to tilt the bladder up by introducing the finger into the rectum, and thus bringing the stone within reach. Difficulty in extraction may occur in consequence of the stone being in some way fixed to, or retained in the bladder; thus, a small calculus may be envel- oped by the folds of the mucous membrane, and in this way elude the grasp of the forceps. Under these circumstances, there is nothing for the surgeon to do but patiently to try to disentangle and remove the calculus by means of the finger and scoop, if it can be so reached; if not, by expanding the forceps in the bladder, to try to push aside the mucous membrane that surrounds it. In consequence of spasm of the bladder, it has occasionally happened that a calculus is so firmly fixed as not to admit of the application of the forceps, the blades of which cannot be introduced between the walls of the viscus without using an improper degree of force, and giving rise to the danger of rupturing the neck of the bladder. Under these circumstances, I think it would be safer for the surgeon to desist from the operation, and in the course of a few hours or the following day, when the spasm might possibly be relaxed, complete the extraction, and thus perform the operation " a deux temps" of Deschamps. The stone may be so fixed between hypertrophied fasciculi in the interior of the bladder, as to be detached with considerable difficulty. In such cases as these the scoop will be found to be the most useful instrument. When the calculus is encysted, its extraction will probably be impracticable, or attended with the most dangerous consequences. Hence, it is expedient not to operate in cases of encysted calculus that are known to be such. If, however, the surgeon has been unfortunate enough to cut into a bladder containing an en- cysted calculus, he must be guided in the course he should adopt by the condi- tion in which he finds the stone. If the aperture leading into the cyst be very small, as in fig. 359, the better plan will be to proceed no further with the opera- tion, as it would be clearly impossible to remove the stone. If, on the other hand, the aperture into the cyst be large, he might feel disposed to make an effort to extract the calculus. With this view he might adopt the plan pursued by Sir B Brodie in such a case, and endeavor to enlarge the orifice of the cyst by means of a probe-pointed bistoury cautiously applied, and then finish the ex- 922 STONE IN THE BLADDER. traction by means of a scoop. Such a proceeding, however, is in the highest degree hazardous, on account of the readiness with which the section might extend into the peritoneal cavity; as well as difficult in execution, from the depth at which the parts are lying. I believe that a calculus may occasionally be encysted, or rather encapsuled, in another way, — by being covered in by a kind of false membrane whilst lying on the floor of the bladder. This condition I found in a child that I cut for stone some years ago. After removing a calcu- lus about the size of a pea, I felt, with the end of the finger, a hard, irregular body, covered apparently by mucous membrane, lying at the inferior fundus of the bladder. On scraping through the membrane covering this with the point of the nail and a curved scoop, I exposed the calculus (fig. 357), and removed it, with a cyst attached to it. On examining the structure of this cyst, which was about the thickness of ordinary writing-paper, of a reddish color, and re- sembling a piece of mucous membrane, it was found to be a false membrane, composed of organized fibro-cellular tissue. The patient made a good recovery, with the exception of a slight attack of secondary hemorrhage which occurred on the eighth day after the operation. The principal difficulty in extracting a calculus generally depends upon the shape and size of the stone. Very flat, broad calculi, those that are round, egg- shaped, or branched, are the most difficult to remove, even though their size be not very great. As a general rule, however, it may be stated that the larger the calculus, the more difficult is its extraction. This arises not so much from the outlet of the pelvis being too narrow, but from the necessity of making the internal incisions through the prostate to a very limited extent. There will always be considerable difficulty experienced in extracting calculi weighing six or eight ounces and upwards, though cases are recorded by Cheselden, Klein, and others, in which calculi from twelve to fifteen ounces in weight have been extracted by the lateral operation. Any calculus above one-inch and a quarter in its shorter diameter will present considerable difficulties in being extracted through an incision in the prostate of the ordinary size; viz., about eight lines in length, even though this be considerably dilated by the pressure of the fin- gers ; and, I think it may be safely said, that a calculus two inches and upwards in diameter, can scarcely be removed by the ordinary lateral operation with any degree of force that it is safe to employ. In the facility with which the calculus is extracted, however, much will depend upon the make of the forceps. As Liston most truly observes, " There can be no more fatal error than to attempt the extraction of a large stone with short and shabby forceps." In these cases, I think the open-bladed forceps (fig. 372) will be found useful, the absence of metal in the most convex part of the blade lessening materially their diameter when grasping a stone. In the event of the calculus being too large to be extracted by the ordinary lateral operation, what course should the surgeon pursue ? Three are open to him : 1st. The division of the right side of the prostate from the interior of the wound. 2d. Crushing the calculus in the bladder, and then removing it; and 3d. The performance of the high or supra-pubic operation. The incision of the right side of the prostate gives considerable additional space, and is suffi- cient for most ordinary purposes; very large calculi being fortunately very rarely met with. This section may be made by introducing a probe-pointed scalpel (fig. 365) into the wound, guided by the index finger, and cautiously divi- ding the right side of the prostate downwards and outwards, in the same way that the section of the left has been made. This procedure must be carefully done, with due regard to the important parts in the neighborhood of the gland In two cases I have seen Mr. Liston do this. In one the patient recovered, in the other he died of diffuse cellular inflammation of the pelvis; and I had occasion recently to practise it on a patient whom I cut at the hospital, and who made an excellent recovery. The second plan, that of crushing the calculus DIFFICULTIES IN LITHOTOMY. 923 Fia. 384. in the bladder through the wound in the perineum, would certainly be a very hazardous procedure. The irritation that would necessarily be set up by the large lithotrite or crusher (fig. 384) that has been invented for this purpose, by the presence of the fragments of stone, and by the necessary difficulty and delay of clearing them out of the viscus, would probably be fatal to the patient. In the event of its being impossible to extract the calculus through the perineum, I think it would be safer to adopt the third course, and to perform the high operation, which will presently be de- scribed. The principal accidents that may occur during the performance of the lateral operation of lithotomy are hemorrhage; wound of the rectum; cutting the bulb, or missing the membranous portion of the urethra. Hemorrhage during lithotomy may occur from three sources: — 1st. The superficial arteries of the perineum; 2d, the deep arteries of this region; and, 3d, the prostatic veins. Hemorrhage from the division of the superficial or the transverse artery of the perineum is sel- dom of a very serious character, though occasionally if these vessels are of larger size than usual, they may furnish a serious quantity of blood; under such circumstances their ligature would be • » i. i required, and might be practised either before or after the extraction of the cal- culus It is better, if possible, to wait until the completion of the operation, lest the ligature be pulled off during the removal of the stone. The division of the deep arteries of the perineum, that of the bulb and the internal pudic, will be attended by far more serious and perhaps even fatal consequences; as, from the depth at which the vessels are seated; it would almost be impossible to apply a ligature to them unless the patient be very thin, and the perineum propor- tionately shallow. In the event of a ligature not being applicable, the surgeon would have to trust to plugging the wound around the tube, or to the pressure of an assistant's fingers continued for a considerable time. The pressure of the fingers of relays of assistants, kept up for a considerable length of time is per- haps the surest mode of arresting the hemorrhage. The pressure must be kept up for many hours; thus South relates a case in which it was maintained for fourteen hours, and Brodie one in which, after twenty-four hours, it succeeded. The assistants should not be changed more frequently than necessary, each keep- in* up pressure for two or three hours, and removing his fingers as cautiously as possible It is, doubtless, very rare for these arteries to be wounded when they follow their usual course, though such accidents ^W^^j£^ ft some of the most skilful lithotomists, such as Home, Bell, Roux, and .Desault. It waTthe opinion of the late Mr. Key that the artery of the bulb was generally Z dnrinSTithotomy, but in this I believe he was mistaken so far as its trunk s concerned, though doubtless in many cases the bulb itself may be wounded, and the S 0f twigs in which the vessel terminates divided; but this would Totyie d an alarming°hemorrhage. The trunk of the artery of the bulb would, 924 STONE IN THE BLADDER. however, be endangered by opening the urethra too high up, and lateralizing the knife too early, and might bleed very freely. The internal pudic artery, bound down by a strong fascia and under cover of the ramus of the ischium, runs but little risk unless the knife be lateralized too much, and the incision be carried too far outwards. It is in some of the anoma- lous distributions of these vessels that the greatest danger would be occasioned. The artery of the bulb, the inferior hemorrhoidal, the dorsal artery of the penis, or the internal pudic may take such an anomalous course that their division must be inevitable; and as the surgeon has no possible means of knowing beforehand whether the distribution of the arteries is regular or not, and as his incisions are all planned on the supposition that they are, he is not to blame in the event of a vessel being accidentally divided when taking an abnormal direction, which it is impossible to be acquainted with until after the accident has occurred. Venous hemorrhage of an alarming and even fatal extent has been known to occur from division of the prostatic plexus. This is especially apt to happen in old people, in whom these vessels not only become greatly enlarged, but do not readily contract on account of the rigidity of the neighboring parts. Plugging may avert this. A wound of the bulb is not of very uncommon occurrence in lithotomy, and I believe is of no consequence beyond furnishing a small additional quantity of blood. Indeed, the bulb is so situated, in many cases overlapping the mem- branous portion of the urethra, that this can scarcely be opened without wound- ing it. In other cases, again, the surgeon may go into the opposite extreme, and open the urinary passages altogether beyond the membranous portion of the canal. I was present some years ago at the post-mortem examination of a fatal case of lithotomy, in which perhaps the most skilful operator of that day had opened the bladder beyond the prostate, leaving the urethra altogether untouched. Wound of the rectum may occasionally occur either in consequence of the staff being too much depressed, the edge of the knife turned too directly down- wards, or the rectum being distended and overlapping the sides of the prostate*. If the aperture in the gut be but of moderate size, it will probably close as the wound granulates and fills up. If, however, the incision be more extensive there will be the risk of a recto-vesical fistula being induced; under such circumstances, treatment such as recommended for that disease should be adopted; or, perhaps it might be better at once to meet the difficulty by laying open the rectum through the sphincter into the wound. SOURCES OF DANGER AND CAUSES OF DEATH AFTER LITHOTOMY. Lithotomy, even in healthy subjects, is always a dangerous operation, and though the rate of mortality doubtless depends greatly upon the dexterity and skill of the operator, more is, I believe, due to the constitution and age of the patient. Sir B. Brodie most justly says, " Success in lithotomy most un- doubtedly depends in a great degree on the manual skill of the surgeon, and on the mode in which the operation is performed; but it depends still more on the conditions of the patient with respect to his general health, especially on the existence or non-existence of organic disease." That the mere cutting into the bladder is not a very dangerous proceeding, provided that viscus and the kidneys are healthy, is evident from the fact that in those cases in which surgeons have had to extract bullets, bits of catheter, &c, from this organ, bad consequences have rarely occurred, though the operations have often been tedious; but in lithotomy the case is different, for here the bladder is not only usually in a state of chronic irritation, but the kidneys are frequently diseased, and these conditions influence more materially the result of these operations I DANGERS OF LITHOTOMY. 925 than any other circumstances. Hence an operator may have a run of unsuc- cessful cases; or by a fortunate concurrence of favorable cases it has occasion- ally happened that a surgeon has cut 20 or 30 patients in succession without losing a single one; but several deaths then occurring, though the operation was performed in the same way and with the same care as before, his average falls to about the usual level. The late Mr. Lynn had cut 25 patients without losino- one, and he said that he thought he had at last discovered the secret of performing lithotomy with success; but, he added, the Almighty punished him for his presumption, for he lost the next 4 cases that he cut. Mr. Liston, during a period of six years, in which he operated 24 times, lost no patient from lithotomy at University College Hospital; but out of the whole 37 cases which he cut during the period of his connection with that Institution there were 5 deaths; reducing the average to 1 in 7-2. This success was, however, very "Teat when it is taken into consideration that most of these cases occurred in adults, and that many of them were of a very serious character. I find on reference to the Hospital Records, that only 7 of the patients were under 10 years of age, whilst 14 were above 50; of these, two were 80 years of age, of whom one died and the other recovered. I believe that Mr. Liston only lost one patient under 60 years of age, and that was a lad of 18 in whom he found it necessary to divide the right side of the prostate as well as the left, and who died of infiltration of urine. Thirty-eight patients, successively operated on at the Norwich infirmary, recovered; but the average rate of mortality in that Institution, calculated from 704 cases, has been 1 in 7|.' Cheselden only lost 1 in every lOf; and according to Mr. South at St. Thomas's, the mortality has not amounted to more than 1 in 9f; but a good many of these patients were probably children. Sir B. Brodie states, that of the 59 cases operated on in all the London Hospitals in the year 1854, 10 died; making the mortality as nearly as possible 1 in 6. According to Mr. Coulson the average mortality in England deduced from 1743 cases of the lateral operation is 1 in 693 cases; whilst in France it is 1 in 5-7; and for Europe generally 1 in 5-14. Age exercises a marked influence on the result of lithotomy; which may be looked upon as one of the most successful operations in surgery at early periods of life, a hazardous one at middle age, and an extremely dangerous one at advanced age. At the Norwich Hospital lithotomy has been found to be four times as fatal in adults as in children. Mr. Coulson finds on analyzing 2972 cases of lithotomy that the mortality at each successive decennial period is as follows. Below 10 years it is 1 in 13, and thence gradually augments from 10 to 80 years to 1 in 9, 1 in 6, 1 in 5, 1 in 4, 1 in 3-65, 1 in 3-23, 1 m 2-71. The shock of the operation occasionally proves fatal, though probably much less frequently so since the introduction of chloroform, than was formerly the case. Yet, even now, patients occasionally die from this cause, induced eithe by a very much prolonged operation, or by the system being weakened, and hiving lost its resisting power in consequence of disease of the kidneys perhaps of a latent character A prolonged operation, even under chloroform dangerous, and although it is certainly not well to operate against^ tame, yet is undoubtedly advantageous to finish the operation ^ » ^J^JJ M * consistent with the safety of the patient even though he .be ««*f ^ Hemorrhage does not so often prove fatal, either shortly after the operation or atTkter period, as might be expected from the great vascularity of the ar Ltd. "Secondary hemorrhage*; of a dangerous oreven a al character may, however, come on six, eight or ten days aftei^ the^operation 1 have not givmg any externa evidence oi d ith or hnt hemorrhage will usually cease on piugain0 926 STONE IN THE BLADDER. soaked in alum solutions. Should it prove serious, however, the actual cautery may be advantageously employed. In a case that occurred to me on the ninth day, the bleeding was stopped by wiping out the wound with the actual cautery, a practice that Mr. A. Dalrymple informs me was occasionally successfully practised by that excellent lithotomist, his father. Diffuse inflammation of the cellular tissue of the pelvis, especially of those layers around the neck of the bladder, between it and the rectum, and that extend from thence under the peritoneum, is the most frequent cause of death after lithotomy. This inflammation, which is always of the diffuse or erysipeloid kind, followed by rapid sloughing of the textures that it invades, may arise from two causes. 1st. From the urine getting infiltrated into the cellular tissue, in consequence of the incision extending beyond the limits of the prostate, into the loose layers of tissue that surround that gland. 2d. In consequence of the bruising and laceration to which the neck of the bladder, the prostate and the textures between it and the rectum are subjected, in prolonged attempts to extract a large calculus from the bladder. The danger of cutting beyond the limits of the prostate has already been ad- verted to. In the extraction of calculi of ordinary size there can be no neces- sity to extend the internal incision; but when the calculus is of considerable magnitude, the surgeon, wishing to get as much space as possible, may inadver- tently carry his knife beyond the prostate; or, if he make a cut into the right side of this gland, he may perhaps prolong it a little too far, and thus open the loose cellular tissue or fascia that surrounds it, and that is continuous with the pelvic and sub-peritoneal planes of cellular membrane. By dilating the incision in the prostate downwards and outwards, either with the finger or with a blunt gorget, the dense envelope surrounding the gland is not divided, and injury to this tissue is prevented. If the incision extends beyond the prostate, the urine, as it escapes through the wound, sinks into the meshes of the loose cellular tissue over which it flows, and thus gives rise to infiltration, followed by rapidly extending inflammation and sloughing, which speedily involve the whole of the neighboring textures. This mischief generally occurs within the first forty-eight hours, and is indi- cated by the patient being seized with rigors, followed by dry heat of skin, a quick pulse, which, after a time, may become intermittent, and a dry and brown tongue. At the same time he will complain of some tenderness about the lower part of the abdomen, and in the groins; the belly becomes tympanitic, the body covered with a profuse sweat; hiccup comes on, the pulse becomes more weak and fluttering, and death usually occurs about the fourth or fifth day after the operation. In some cases there are more decided signs of peritoneal inflamma- tion ; but, as Brodie very truly remarks, this is not the primary disease, but is only induced secondarily by the inflammation and sloughing of the cellular tissue of the pelvis spreading to the contiguous serous membrane. The treatment of such cases must be conducted on the ordinary principles that guide us in the management of diffuse inflammations. It is only by admi- nistering ammonia with such a quantity of wine or brandy as the state of the system may indicate, together with such nourishment as the patient can take, that life can be preserved. The disease is a depressing one, and requires a stimulating plan of treatment. Brodie has recommended that in these cases a free incision should be made through the sloughy tissues about the wound into the rectum, in accordance with the general principles that guide us in the ma- nagement of similar affections elsewhere. In one case of the kind that occurred under his care, he saved the patient by passing a curved probe-pointed bistoury into the wound to its furthest extremity, to the left side of the neck of the blad- der; he then pushed it through the tunics of the rectum, and, drawing it down- wards, divided the lower part of the gut together with the sphincter; thus laying HIGH OR SUPRA-PUBIC OPERATION. 927 the wound and the rectum into one. The relief was immediate, and the patient recovered. This plan of treatment certainly seems rational and worthy of trial in similar cases. Diffuse inflammation of the cellular tissue around the neck of the bladder and prostate arising from bruising and over distension of the parts during the ex- traction of a large calculus is, I believe, a more frequent occurrence than infil- tration of urine, and fully as fatal. This sequence of lithotomy is especially apt to occur in those cases in which, in consequence of diseased kidneys, or the existence of other organic mischief, the patient is more than usually liable to the supervention of diffuse or erysipeloid inflammation; indeed it is in this indi- rect way that I believe diseased kidneys constitute such a formidable obstacle to the safe performance of lithotomy. In the extraction of large calculi, considerable traction is required and force must be exerted, hence undue bruising and pressure are very apt to be inflicted upon the parts that constitute the line of incision. It is in this way that the danger of lithotomy increases almost in exact proportion to the size of the cal- culus : for here the surgeon is often placed between the horns of a dilemma. He must either cut beyond the limits of the prostate and thus incur the risk of inducing urinary infiltration of, or diffuse inflammation in, the pelvic fasciae; or else by limiting his incision to the margin of the gland, and thus having, per- haps, an aperture of insufficient size, inflict severe injury by the bruising and laceration of parts during forcible and possibly prolonged efforts at extraction. It must, however, be borne in mind, that the larger the stone the more proba- bility is there of the existence of old-standing disease of the bladder or kidneys, and an unfavorable result from this cause. Mr. Crosse, of Norwich, has drawn up a table that shows the influence of the weight, or in other words, the size of a calculus on the results of lithotomy. He found that when the stone was one ounce and under in weight, the deaths were in the proportion of 1 in 11-25 cases. When from 1 to 2 ounces in weight there was 1 death in 6-61 cases. When from 2 to 3 ounces 1 death in 2-18 cases. When from 3 to 4 ounces 1 death in 1-57 cases. When from 4 to 5 ounces 1 death in 1-66 cases. This table, which has been constructed on the results of 703 cases, illustrates very clearly the fact, that the operation for the removal of a large calculus, is far more dangerous than that for the extraction of a small one. The symptoms of diffuse inflammation of the cellular tissue arising from the cause now under discussion, very closely resemble those from infiltration of urine, and the treatment must be conducted on precisely similar principles. HIGH OR SUPRA-PUBIC OPERATION. Although the lateral operation for lithotomy is perhaps the safest for the ex- traction of stones of small or moderate size, yet there can be no doubt that its results are extremely unfavorable, as has already been shown, when the calculus exceeds a certain magnitude; and under these circumstances it may be deemed expedient to perform the high operation in preference to it. It is fortunate, however, that large calculi are comparatively rarely met with. Thus of the 7Ud Norwich cases, that form the basis of Mr. Crosse's tables, and indeed of our chief information on these points, 529 were under 1 ounce in weight; liy weighed from 1 to 2 ounces; 35 from 2 to 3; 11 from 3 to 4; 5 from 4 to 5; and only 4 were above this size. Hence if we confine the high operation to those instances in which the calculus is above such a size as will readily admit of extraction through the perineum, we shall seldom have occasion to perform it; but yet instanced occasionally occur in which no other method of extracting the calculus presents itself. Thus, by this method, M. Uytterhoeven succeeded in extracting a calculus, of which he has kindly given me a cast which rnea- sured 16* inches in one circumference, and 12* in the other, which was per- 928 STONE IN THE BLADDER. fectly moulded to the shape of the inside of the bladder, and which clearly could not have been removed by any incisions through the perineum, as the outlet would have been insufficient for its extraction. The patient survived the ope- ration eight days. But not only may the high operation be required on account of the size of the calculus, it may be rendered necessary by the existence of such rigidity about the hips in consequence of rheumatic disease, as would prevent the proper exposure of the perineum; or, that region might be the seat of disease that would interfere with any operation being practised through it. The high operation consists in making an incision through the abdominal wall, above the pubes, and opening the anterior part of the bladder under- neath the reflexion of the peritoneum that passes upwards from its superior fundus. In performing this operation, it is necessary that means should be taken to raise up the fundus of the bladder, so that it may project above the pubes, and thus admit of being safely opened. With this view various contrivances have been invented, such as catheters containing sliding stylets, which can be pushed through the bladder when that viscus is exposed. These instruments, though ingenious, are not necessary, for the end of an ordinary catheter introduced through the urethra, and made to project above the pubes, would serve as a sufficient guide. In performing the operation, an incision about four inches in length should be carried from the pubes directly upwards in the mesial line. The pyramidales are then to be cut across near their origin, the linea alba exposed, cautiously opened near the pubes, and divided upwards some little way. The peritoneum must next be pushed back and the dissection carefully carried through the cellular tissue above the bone, until the instrument previ- ously introduced can be felt through the bladder, when, if it contain a sliding and pointed stylet, this may be pushed through the coats of the bladder; if not, an incision must be made down upon it, and the aperture in the organ enlarged downwards towards the neck of the bladder by means of a probe-pointed bistoury, so as to admit the fingers. The forceps must then be introduced, and the calculus extracted. After the operation there will always be risk of urinary infiltration into the cellular tissue around the margins of the wound. In order to prevent this, the older surgeons kept the bladder empty by making incisions through the perineum into the membranous portion of the urethra or neck of the bladder, thus complicating seriously the operation; but this accident may best be prevented by introducing a gum-elastic catheter into the urethra, and leaving it there for a few days until consolidation has taken place and the wound shows a disposition to close, pressure being at the same time kept up on the lips of the incision. Another cause of danger in this operation is wounding the peritoneum, which may occur in consequence of the contracted state of the bladder, causing it to lie low in the pelvis, and thus preventing the proper introduction of instruments to carry it up above the pubes. Mr. Humphrey, of Cambridge, has collected 104 cases in which this opera- tion has been performed; of these 31 proved fatal, chiefly from peritonitis and urinary infiltration, the mortality amounted consequently to 1 in 3£; and M. Son- berbielle, one of the greatest modern advocates of this operation, lost 1 patient in 3. The general result, therefore, is by no means satisfactory, though, as in many instances the operation was performed in cases in which the lateral me- thod was not applicable, we cannot with justice compare the two procedures. MEDIAN LITHOTOMY. The median operation of lithotomy is that procedure by which a stone is extracted through an incision in the raphe of the perineum, extending into the MEDIAN LITHOTOMY. 929 urethra behind the bulb. An external incision having been made, and the ure- thra opened, the membranous and prostatic portions of the canal were forcibly dilated or rather lacerated by specially constructed instruments, until a suffi- ciently large aperture was made for the introduction of the forceps and the removal of the stone. This operation, under the name of the " Marian," from Sanctus Marianus, one of its inventors, or "the operation of the apparatus major," from the complexity of the instruments used, held its ground in Europe for two centuries, until its tediousness, the terrible pain attendant upon its per- formance, and the mortality following it, caused it to give way to the lateral operation. It has, however, under various modifications, kept its ground in some schools of surgery, in that of Paris more especially, and has of late years been reproduced in a simplified manner in Italy by Borsa and Mauzoni, and in this country by Mr. Allarton. With the old Marian operation, which has justly been discarded from surgi- cal practice, we have now nothing to do, but its modern modification deserves some attention. The steps of the median operation as modified by Mr. Allarton are as follow:— The patient having been placed in the proper position for lithotomy, and a staff deeply-grooved along the convexity introduced into the bladder, the surgeon passes the left index finger into the rectum, and feels for the prostate. He then pushes a long sharp-pointed bistoury, with the edge turned directly upwards, into the mid line of the perineum, a little above the anal aperture, so as to open the membranous portion of the urethra immediately in front of the apex of the prostate. The finger in the rectum serves as a guide to this part of the canal, and prevents the point of the knife wounding the gut, warning the surgeon of its too near approach. When the staff is reached the incision is carried upwards to a sufficient extent. A steel ball-probe is then passed along the groove into the bladder, and the staff withdrawn. The surgeon, using the probe as a guide, now proceeds gradually to insinuate his left index finger along it into the pros- tatic portion of the urethra and the neck of the bladder, dilating these passages as he proceeds. Having got his finger into the bladder and felt the stone, he withdraws the probe, introduces the forceps, and extracts the calculus in the usual way. This operation is said by its advocates to possess several advantages over the lateral one, being more simple and easy of execution, attended by less hemorrhage, by the dilatation and not the section of the prostate, and admitting of the easy extraction of the stone. . Let us briefly examine these supposed advantages, and compare the mesial and lateral operations. ...,.,, As to simplicity and ease of execution, there can be little doubt that that ope- ration will be easiest of execution which a surgeon is most in the habit ot per- forming, and in this respect the mesial and lateral appear to me to be much on * With regard to the avoidance of hemorrhage, the mesial has certainly the advantage. If the surgeon carefully cut in the middle line no blood-vesse of importance can possibly be divided, and even though the bulb be freelypoised, we know that, as in the perineal section, no bleeding of ^sequence likely to ensue, whilst in the lateral, the artery of the bulb, if not Ae internal pudic, must always be in some danger; and even from the superficial vessels the bleed- ^e^e^j difference in the treatment of the prostate^s dihata tion in the mesial, and its section in the lateral, I believe it to be m man, c,es more imaginary than real. In the lateral operation most «™^» »f*^£ that the internal or deep incision should be as limited as P,°«f ^ ™Vv fte ing the apex of the prostate, and that dilatation ^ould be effec ed Jy the pressure of the fingerf so in the mesial, the apex of theprostate is notehed and dilatation is effected with the finger. In both cases I believe that the so 59 930 STONE IN THE BLADDER. called dilatation is in reality a partial laceration, a breaking down or opening out of the structure of the prostate rather than a true expansion of its sub- stance. I have often examined the prostate in the dead subject after it has been subjected to this process of dilatation, and have always found it more or less torn. The next point for comparison is as to the relative facilities presented by the two operations for the manipulation of the forceps and the extraction of the stone. In the adult, the main difficulty of lithotomy does not lie in getting into the bladder, but in getting out the stone. And the difficulty and danger increase in proportion to the size of the calculus; the tissues between the neck of the bladder and the perineal integuments must either be widely cut or exten- sively torn and bruised to allow of the passage of a large stone. No amount of simple dilatation of which these tissues are susceptible can make a passage through them that will allow of the extraction of a stone H or 2 inches in diameter; such a stone must either be cut or torn out. Now what space have we in the median operation for the introduction of the forceps and the extrac- tion of a large stone ? Here, I think, is the weak point of the modern opera- tion. In it the incision is made, and all the manipulation is practised towards the apex of the narrow triangle formed by the rami of the pubes. The base of this triangle is represented by a horizontal line corresponding to the level of the membranous portion of the urethra, and consequently does not occupy the widest part of the perineum, and is formed by the transverse muscles of the perineum and the lower portion of the deep fascia, supported and filled up by the rectum and the tissues which are attached to and support the gut on either side, and which form a rigid wall or barrier stretching across the perineum, which cannot be depressed, and which requires to be divided laterally into the ischio-rectal fossa, before a stone of any considerable magnitude can be removed. It was in consequence of the extensive bruising and laceration of these struc- tures, and the difficulty experienced in getting the stone through them, that the old Marian operation fell into disuse. This difficulty, however, is only met with in the extraction of calculi of large size. Small flat or elongated calculi, foreign bodies, such as bits of broken catheter, pencils, etc. may very readily, conve- niently, and safely be removed through the narrow space in which the incision of the median operation is carried. In summing up the comparative merits of the modern median and the lateral operations of lithotomy, I think it may be said that the great advantage pos- sessed by the median is in the absence of all serious danger from hemorrhage, but that the great objection to it consists in the triangular space in which it is performed being too narrow to allow of the extraction of large calculi. In the lateral operation there is undoubtedly more danger from hemorrhage, but this is more than counterbalanced by the greater facility for extracting the stone. In conclusion, I should say that in all cases in which the calculus is large, the lateral operation should be performed; but when of small size, and especially if narrow, whether single or multiple, the median operation, as recommended by Mr. Allarton, might be substituted, provided it be not thought advisable, as is now generally done, to subject such cases to lithotrity; and that, in cases of the lodgment of foreign bodies, especially of pieces of broken catheter, the median possesses advantages over the lateral operation. In the case also of cal- culi which are too large to be successfully subjected to lithotrity, but which, if removed by the lateral operation, are attended by a frightful rate of mortality, it seems to me that the median operation might possibly be advantageously com- bined with lithotrity. The stone having been broken up at one sitting, the fragments might at once be extracted through a limited incision, in the mesial line of the perineum. The bi-lateral operation of Dupuytren is a modification of the median. In LATERAL AND MEDIAN LITHOTOMY COMPARED. 931 made across the perineum, half an inch above the Fio. 385. it a transverse incision is anus, the horns of the incision extending to two- thirds of the distance be- tween the anus and the tuber ischii on either side (fig. 385). The dissection is carefully carried down to the central point of the perineum, and the mem- branous portion of the urethra is opened on a grooved staff previously introduced; along this the double lithotome cache* is passed (fig. 386), the blades expanded to a pro- per distance, previously regulated, and both lateral lobes of the prostate divided to a corresponding extent downwards and outwards in withdrawing the instrument. The extrac- tion of the stone is then effected in the usual way. This operation appears to me not to have received the attention from surgeons in this country that it deserves. By it the prostate is divided equally on both sides in its greatest diameter; if the expansion of the lithotome is care- fully guarded, there is no danger of going beyond the limits of that organ, or of wounding the internal pudic arteries, and the interior of the bladder is reached by the most direct and the readiest passage. In withdrawing the lithotome, its concavity should be turned downwards and the handle well depressed. The median and bi-lateral operation might, I think, be advan- tageously combined, and thus the chief objections to both be got rid of. This kind of operation I have often practised on thedead subject, and it appears to me to be one well deserving a trial on the living. It is easy of execution, seems likely to be attended by little nsk of hemorrhage, of urinary extravasation, or of pel- vic inflammation, and opens the bladder at the part where it is nearest the perineal surface. It may be performed as follows: The patient having been tied up, and a staff deeply grooved along the convexity passed into the bladder, the urethra is opened at the membranous part with the edge of the knife turned upwards, as described in the median operation; the double lithotome is then slid along the staff into the bladder, its concavity turned downwards, the blades expanded to but a limited extent, and the prostate and the soft structures between it and the surface incised as it is withdrawn. If the stone is of but moderate size, the in- cision may be confined to one side only, and made with a probe- pointed bistoury. It will be found that sufficient space is obtained by the perpendicular incision in the skin, whilst the limited transverse^cut re- ufoves that tension and resistance of the deeper structures which inhe ™li- nary median operation interfere seriously with he ^^^^^^ and the extraction of the stone, and by the division of both sides of the prostate to a limited extent abundance of space is obtained. 932 STONEINTHEBLADDER. URETHRAL CALCULUS. Calculi are not unfrequently met with in the urethra, especially in children, passing from the kidney perhaps into the bladder, and from thence into the urinary canal, through which they occasionally escape, but in other instances lodge, more especially at the bulb or in the navicular fossa. These calculi are commonly of the lithic acid, lithate of ammonia, or oxalate of lime varieties; they are frequently round, but not uncommonly elongated or spindle-shaped. There is reason, however, to believe that calculi Fig. 387. may form in the urethra. One of the most re- markable instances of this kind is represented in the annexed cut (fig. 387), taken from a drawing in Sir R. Carswell's collection at University College. In cases of tight stricture, sabulous or calculous concretions may occasionally be formed behind the constriction. The presence of a calculus in the urethra may always be determined by the difficulty that is occasioned in micturition, by the possibility of feeling the stone through the walls of the canal, or detecting it by introducing a sound into the urethra. The removal of these calculi may be effected either by extraction or excision. When situated towards the anterior part of the canal, a urethral calculus may frequently be extracted by passing a long and very narrow-bladed pair of forceps down to it, by which it is seized and drawn forwards; occasionally when it has reached the navicular fossa, it cannot be got through the urethral orifice without dilating this by incision with a probe-pointed bistoury. If the calculus is too large to be extracted in this way, and appears to be firmly fixed, an incision may be made down upon it, through the urethra, by which it may be removed. It is a good rule not to make this incision in any part of the urethra anterior to the scrotum, for in consequence of the coverings of the penile portion of the urethra being very thin, the aperture will probably not be closed, but a fistulous opening left. When the stone is situated in the scrotal portion of the urethra, there would be some risk of abscess and of urinary in- filtration if the incision were made through the lax tissues of the scrotum. Hence, it is better, if possible, to push the stone back towards the membranous portion of the canal, to cut down upon, and extract it here. This operation may readily be done by passing a staff, grooved, along its convexity, or an ordi- nary director as far as the calculus, and making an incision upon the end of this, so as to lay open the urethra; the staff is then removed, and the calculus ex- tracted by means of a slender pair of forceps. A catheter should next be passed into, and retained in the bladder for a few days, in order to lessen the tendency to the formation of urinary fistula. It may happen that the calculus, which is impacted in the urethra, is only one of several that are lodged in the bladder. In order to ascertain this, the surgeon should, after removing the calculus for which the operation has been performed, pass a sound into the bladder, so as to ascertain whether any other concretions exist in that organ; and if so, they should at once be removed by extending the incision made into the membranous portion of the urethra into the bladder, by the lateral operation of lithotomy. In this way I once saw Mr. Liston extract two vesical calculi after having removed one that had blocked up the urethra. PROSTATIC CALCULI. — LITHOTRITY. 933 PROSTATIC CALCULI. Prostatic calculi differ from all other urinary concretions in situation and composition, being formed in the ducts of the prostate gland, and composed principally of phosphate of lime and some animal matter; usually about 85 per cent, of the phosphate, to 15 of the organic ingredient. They generally occur in old people, though they may sometimes be met with in young subjects. From a lad of nineteen, whom I cut for vesical calculus, I extracted two of these prostatic concretions. They are usually of a grey or ashy color, somewhat triangular in shape, smooth and polished (fig. 388); having facets, being very hard, and seldom much larger than a cherry or plum-stone; though they may occasionally attain a considerable bulk, having been met with as Fig. 388. large as a hen's egg, and then presenting a branched or irregular appearance. Though usually but one or two exist, which are sometimes deposited in a kind of cyst in the gland, as many as thirty or forty have been met with, its whole tissue being studded with them. Prostatic calculi give rise to a sense of weight, pain, and irritation in the perineum, and often occasion a tolerably free secretion of mucus from the gland. On introducing a sound this passes over them, striking the calculus with a distinct click before its beak enters the bladder. This is increased by the finger in the rectum pushing the gland up, and thus bringing the stone in more direct contact with the sound. In some cases the stone may be felt through the coats of the rectum. The treatment consists in introducing a grooved staff and cutting down upon the prostate in the mesial line, until the calculi are reached, when they may be extracted with the forceps or scoop. When complicated with vesical calculus the lateral or modified median operation should be performed, and the stones removed as they present themselves. LITHOTRITY. The operation of lithotrity, by which the stone is crushed in the bladder and the fragments expelled through the urethra, is of modern, and indeed, of very recent invention; for notwithstanding that various rude and incomplete attempts may at different times have been made with this view, it was not until about the years 1818 or 1820 that the subject began to attract serious attention. About this time Civiale, followed by Amussat, Leroy, and others, began constructing instruments, which though very imperfect, yet were sufficient to break down a calculus in the bladder. From this period the system made rapid progress, and the successive improvements made by the surgeons whose names have just been mentioned, together with the ingenious mechanical adaptations introduced by Weiss, Heurteloup, Costello, and Charriere, enabled the surgeon to attack the stone with certainty and effect. It is, perhaps, principally due to the labors of Civiale and Amussat in France, and of Brodie and Liston in this country, that the system has been reduced to its present state of perfection. Before proceeding to the operation of lithotrity, it is necessary that the patient's constitution should be carefully attended to, and especially that all local irrita- bility about the urinary organs should be subdued by ordinary medical treatment. This is even of much greater importance in lithotrity than in lithotomy. In lithotrity we must always expect that any existing irritation or inflammation of the bladder will be increased by the necessary introduction of instruments and the presence of sharp fragments of calculus in the bladder, and their passage aloncr the urethra; but in lithotomy all source of irritation is at once removed 934 STONE IN THE BLADDER. by the extraction of the stone. Before determining to perform lithotrity then, it is necessary to examine very carefully the condition of the urinary organs, and if these be diseased, it will probably be requisite to abandon the operation. The conditions that the surgeon has principally to look to before lithotrity is determined on are, 1st, the characters of the stone; and, 2d, the state of the urinary organs. In order that lithotrity should be successful, it is necessary that the stone should not be above a certain size, that it be not too hard, and that more calculi than one do not exist. The urinary organs must also be in a healthy state and free from irritation. 1st. As to the characters of the stone. With regard to the size of the cal- culus, it may be stated generally, that the smaller it is, the greater will be the success of the operation. As a general rule, it is not well to attempt to crush a calculus above an inch or an inch and a half in diameter. It is not that a large stone cannot be broken; because in most cases, this might readily enough be done; but because the quantity of fragments resulting would be so great that the bladder would in all probability not be able to get rid of them; or, the necessary operations for their disintegration and removal would occasion a dan- gerous amount of irritation. The size of the calculus may always be readily ascertained by seizing it in the lithotrite, and then measuring it by the gradu- ated scale upon the handle of the instrument. If there are several stones, lithotrity is not a very successful procedure; for although each calculus may be a small one, yet the aggregate of the whole is considerable; and besides this, the small calculi will each require a separate operation, as it were, and may each contain a hard and possibly very resisting nucleus. The hardness of the calculus influences materially the question of lithotrity. If the concretion is very hard, especially if composed of oxalate of lime or lithic acid, giving a very clear and ringing sound, the case will not be a veiy favorable one for crushing. For not only may the density of the calculus be such as to cause it to resist any force that it may be safe to bring to bear upon it; but if broken, it will splinter into sharp and angular fragments which cannot readily be ground down, but will greatly irritate the bladder, and will probably escape with difficulty through the urethra. The most favorable calculi for crushing are those that are soft and friable, as the different forms of phosphatic concre- tions ; though in this diathesis the shattered state of system and irritable con- dition of the urinary organs often counterbalance the advantage that would other- wise have been derived from the character of the stone. 2d. The conditions of the urinary organs that influence the propriety of per- forming lithotrity have reference to the state of the urethra, of the prostate, the bladder, and the kidneys. If the urethra be the seat of stricture, or is very irritable, lithotrity, which may require the frequent introduction of instruments and will entail the con- tinued passage of fragments of calculus, cannot be performed. If the prostate be enlarged, more particularly if the third lobe is very promi- nent, the introduction of the lithotrite will be attended by considerable difficulty, and a dependent pouch will be found at the lower fundus of the bladder, into which the fragments of the crushed stone are apt to fall, and from which they cannot be expelled; hence such a condition of the gland as this, is a serious, though perhaps not an insuperable bar to the performance of any crushing operation. The state of the bladder deserves especial attention; the circumstances con- nected with it that principally militate against lithotrity are a very irritable con- dition of it; its being contracted, hypertrophied, or sacculated. A very irritable and sensitive bladder not only will be the seat of severe suffering, but may not admit of holding sufficient water to make the operation a safe one, and may readily become dangerously inflamed in consequence of the repeated introduc- OPERATION OF LITHOTRITY. 935 tion of instruments, and the presence of angular fragments. Hence, if the ordi- nary operation of sounding occasion much distress; if the patient cannot hold his water long, and passes it in small quantities; if it be bloody, or much loaded with viscid mucus, he will scarcely be able to bear the procedures necessary for the operation. In some instances, however, the irritability of the bladder may be overcome by keeping the patient in bed, and, as Sir B. Brodie recommends, daily injecting tepid water. At the same time it must be borne in mind that the bladder may be in an opposite condition in cases of stone, having fallen into a state of atony; and this, as Civiale has pointed out, may be a source of great danger after lithotrity, the organ not possessing sufficient expulsive power to rid itself of the fragments with which it is encumbered. A sacculated condition of the bladder is also a serious objection to lithotrity, as not only are the fragments likely to lodge in the sacculi, but these cysts become filled with an offensive puriform fluid, and thus may occasion low or typhoid cystitis, followed perhaps by pyemia. Lastly, the condition of the kidneys merits special attention. If these organs be much irritated, as indicated by the presence of casts of tubes, or of a consi- derable quantity of albumen in the urine, or in any other way, the performance of a series of operations in the bladder would be likely materially to increase the mischief in them, and consequently ought not to be undertaken. The ao-e also of the patient must be taken into account, though lithotrity can doubtless be performed at all periods of life. The small size of the urethra before puberty is such as scarcely to admit of the ready introduction of the necessary instruments, or of the escape of fragments of calculus; and hence it is rarely had recourse to at this period of life. So also at advanced ages the irritable state of the urinary organs, the tendency to the supervention of low cystitis, and the condition of the prostate, are usually such as to prevent the performance of the operation. _ . Supposino-, however, that a case is met with in which the calculus is ot mo- derate size, single and not too hard, the urinary organs healthy, and not over sensitive, and the patient an adult but not too aged, the surgeon may have recourse to lithotrity with every prospect of readily and permanently Seeing the patient of his calculus. In performing the operation in such a case but little preparatory treatment is needed, though it is well to keep the patient quiet for a few days, and to regulate his bowels before anything is done Operlton of Lithotrity. -The instruments required for lithotrity^ are.the following An ordinary sound with a short beak to examine the condition of he bladder Ahollow steel sound, through which the bladder may, if neces- ary be iniectfd after or during sounding, without the necessity of changing he^ bstrument rfit 362). This I have found of especial service in the later tag« of™: opSion for detecting small foments. A£j«^ synnfe fitted with rin«s and havino- a large piston rod, so that it may work easily, this stiouia Idmit of ad^tation to ih? follow sound. A ^"f-d sdver cathet Wlth large round o oval eyes and^^^^^^^2^ ^Isy^ fragments consist of Weiss' lithotrite as represer^ed in the an^ «ed ™t (^ 389) ; or a similar instrument worked by a rack «d pm^on , his ^oweve the d sadvantage of possessing less power than the tra ^fcjcrew _L trite must be m'ade of well-tempered steel i^^^^^T^a^ tt ^zHs'^ 936 STONE IN THE BLADDER. the case with some cheap instruments, be made of a plate of this metal, turned up at the edges; as such a one possesses too little strength to be used with safety. The scoop may, however, be so constructed without danger. Fig. 389. The scoop, such as is represented (fig. 390) and invented by Civiale, has a double action, enabling the surgeon to work it either by the hand or a screw; it is furnished with a kind of spoon-shaped beak, which is somewhat flattened, and admits of the extraction of a certain quantity of detritus. Of late, this instrument has been improved by Mr. Coulson, by being made more solid and strong, and having a fenestrum in its beak, so that it can be used as a litho- trite. Besides these instruments, a small lithotrite is occasionally used for crushing fragments in the urethra; and another instrument, shaped like that represented (fig. 131), for withdrawing them from that canal. Fig. 392. The operation of lithotrity may be divided into three stages. 1st. The intro- duction of the instrument. 2d. The search for and seizure of the stone. 3d. The crushing of the stone. These we shall consider successively. 1st. Lithotrity may be performed with the patient either lying on his back upon a hard mattress, or a couch or table; or it may be practised, and in some cases most conveniently, in the sitting posture. The surgeon, standing on the right side of the patient, carefully introduces the hollow sound or catheter, and OPERATION OP LITHOTRITY. 937 draws off the urine; he then slowly and very cautiously injects the bladder by means of the brass syringe, with from four to eight ounces of tepid water. The use of drawing off the urine is to make sure of the bladder holding the proper quantity of fluid when it is afterwards injected, and the object in injectino- it is to distend it with fluid to such an extent as to prevent the mucous membrane being seized in the grasp of the lithotrite, or injured by the splintering of the stone. The instrument is then withdrawn after the situation of the stone has been detected by it, and the lithotrite is introduced. As this is straight, with a sharp elbow near the beak, some little skill is required in passing it. In doing so, the surgeon must keep his eye upon the short curved beak of the instrument, the direction and position of which must be constantly observed or rather judged of, and especial care must be taken in carrying it under the pubes, not to injure the urethra by pushing the beak of the lithotrite forwards too suddenly, instead of winding it, as it were, under the arch of that bone. In doing this, the instrument should first be introduced nearly parallel to the abdo- men, the penis being held between the left fore and middle finger and drawn over it. As the lithotrite passes down, it must be gradually raised to the per- pendicular position ; and as its curve passes under the pubes, the handle should be depressed between the thighs. The direction of the curve is the thing to bear in mind, and the position of the handle must be varied in accordance with the course that this takes. The lithotrite should be well greased with olive- oil, so that the branch and screw may work smoothly. Lard or ointment should not be used for this purpose, as it is apt to clog and to entangle gritty bits of calculus. 2d. The next point is to search for the stone, which will generally be found in the situation where its pressure was detected during the sounding of the bladder; most frequently at the right side or at the inferior fundus. Should it be situated in a sacculus or depression in this region, it may most readily be seized by introducing a finger into the rectum, and raising up the lower part of the bladder. Sir B. Brodie strongly advises that the lithotrite should never be used as a sound to ascertain the position of the stone; by doing so, the patient suffers pain, the bladder is irritated, the water expelled, and the stone not readily seized. In seizing the calculus, a good deal of tact is required; this Fig. 393. part of the operation may generally be best done by pushing the female blade of the lithotrite against the inferior fundus of the bladder, pressing gently down 938 STONE IN THE BLADDER. with it so as to make a conical depression in this situation, and then inclining the beak towards the stone, drawing back the male blade with the thumb (fig. 393); with a slight shake or jerk, the surgeon then tries to get the calculus between the blades at the same time that the male branch is being pushed for- wards to seize it. In this manoeuvre the female blade should be moved as little as possible, but the stone must be seized by pressing the thumb upon the half circle of steel fixed on the male branch. In this way the stone may often be seized at the first attempt, but in other cases it is not grasped until after several efforts have been made to fix it; the calculus, especially if round, slipping awav from between the blades of the instrument, and being merely scraped by thenl'. In these manoeuvres all rough handling must be most carefully avoided, and the instrument should be turned about as little as possible. It is far safer to desist in the operation if there be any difficulty in seizing the stone, than to persevere in repeated and fruitless attempts, by which the bladder may be severely injured and inflamed. Bather than do this the patient should be allowed to get up and move about for a few minutes, when the position of the stone may be so far altered that it admits of being seized. 3d. When the stone has been seized, it is gently raised in the grasp of the lithotrite, so as to be placed about the middle of the bladder, and it is then crushed. This important step of the operation, like all the others, requires to be deliberately and carefully done (fig. 394). If Civiale's improved lithotrite be used, the stone, if small, may readily be crushed by the pres- sure of the hand alone, without the action of the screw (fig. 392). If, by the ordinary lithotrite, it should not be effected by suddenly and forcibly screwing up the instrument, but the screw should be gradually worked by a series of short and sharp turns, so as to consti- tute almost percussive movements (fig. 391). In this way, the calculus is generally made to crumble down, rather than to fly asunder, and as it yields, the screw must be worked tightly home. The blades of the in- strument may then be opened again, a fragment of the broken calculus seized and crushed in the same way as before, and thus the disintegration of the stone is in a great measure effected and sometimes com- pleted at one sitting. It is of the greatest moment, however, that too much time be not consumed at one sitting. Nothing is more dangerous than the long- continued contact of instruments with the interior of the bladder; in this way great irritability, or an ato- nic condition of this organ, terminating in low cystitis and pyemia, is apt to be produced, and death may thus result. The shorter the sittings, the more likely will the case do well. The first sitting should not exceed ten minutes, and the subsequent ones five. In the repetition of the sittings, the surgeon must be guided by the effect produced on the stone and on the bladder. The calculus may be entirely destroyed in one sitting, but most commonly from three to five or six are required; these should, if possible, be conducted at intervals of three or four days, though this must depend upon the amount of irritation induced by them. Usually at the first sitting, it is sufficient to break up the stone; the frag- ments being left to be dealt with subsequently. In crushing these, especially when they lie behind the prostate, M. Civiale turns the concave part of the Fig. 394. ACCIDENTS OP LITHOTRITY. 939 beak downwards, and seizes the fragment in this position. In doin°- this, however, great care must be taken not to nip the mucous membrane of the bladder. Before withdrawing the lithotrite, the surgeon must be careful to see by the scale on the handle, that the male blade is well home. If this be not the case, and the instrument be enlarged by any fragments or detritus being entangled between the blades, laceration of the neck of the bladder or urethra might occur in attempting to withdraw it. After the stone has been crushed, but little detritus will usually escape during the first twenty-four hours, but after this it begins to be expelled; in some cases* in considerable quantity each time the urine is passed. In others, it does not escape so readily, and then the surgeon requires to introduce the scoop (fig. 390), by which he can seize the smaller fragments, crush them up, and screw- ing the instrument home, extract the beak filled with detritus. In usino- this instrument, care must, however, be taken not to get hold of too large a frag- ment, for in breaking this up, whether by the hand or screw, the beak may be clogged with the detritus in such a way that it does not readily close, and then there might be considerable difficulty in withdrawing it. Should this accident occur, the scoop may be emptied by passing its beak back into the bladder, tap- ping sharply upon the instrument, and moving the male branch to and fro. After each sitting, the bladder should be washed out by injecting it with tepid water through a catheter with large eyes; or, what is better, a double- current catheter. In using the latter instrument, the point of which should be directed towards the inferior fundus, a considerable quantity of water may sometimes with advantage be pumped through the bladder by adapting a flute- valve syringe to it. When the surgeon believes that he has pretty well emptied the bladder of the detritus, he must carefully explore the organ by means of a short-beaked or hollow sound; and if he detect any fragment, however small, it must be seized, crushed, and removed with the scoop. During the whole of the treatment, it is necessary to adopt means to allay irritation; with this view the patient should be kept in bed, or on a couch; a moderate diet only should be allowed, plenty of demulcent drinks given, such as barley-water, soda-water, or milk, and opiates or henbane, if necessary, exhibited. ACCIDENTS AND DANGERS OF LITHOTRITY. In considering the accidents of lithotrity, I put out of consideration those that may arise from the surgeon acting carelessly or with improper force, and thus occasioning laceration of the urethra, or injury to the coats of the bladder; so also accidents occurring from the bending or breaking of the instruments will scarcely happen if these have been properly tested on a piece of sandstone grit before being employed in the bladder. The most dangerous accident arises from the impaction of some of the angular fragments of stone in the urethra. They are especially apt to lodge about the bulb and there give rise to a very great degree of irritation, and even of fatal mischief producing great constitutional disturbance of an irritative and asthenic'type. When the fragments are impacted low down in the urethra, it is absolutely necessary to remove them from the canal as speedily as possible, 940 STONE IN THE BLADDER. lest the constitutional disturbance occasioned by them prove fatal to the patient. This may be done in various ways; it has been proposed to push them back into the bladder with a soft bougie, or by injecting a stream of water into the urethra through an open-ended catheter; but these devices are not very likely to be successful, and may give rise to risk of laceration of the urethra. It has been proposed to crush them in the urethra with a small lithotrite (fig. 395); but this plan is somewhat hazardous, as it is very difficult to avoid pinching up the mucous membrane of the canal with the bit of stone. Fig. 396. The safest practice seems to be, either to extract them through the urethral orifice, or to cut them out through the perineum. Extraction through the urethral orifice may be effected by the forceps (fig. 396), or by Civiale's instrument (fig. 131). Should this means fail, or should the fragment be very deeply seated, as in the membranous portion of the urethra, the better plan would be to make an incision directly down upon it, and to remove it through the perineum. If such an operation as this be required, the surgeon might possibly feel disposed to extend the incision a little, and empty the bladder of any remaining detritus by means of a scoop. The principal dangers in lithotrity arise from the state of the bladder and kidneys; — by the induction of cystitis of a low form, atony of the bladder, or renal irritation, or by the occurrence of pyemia, with much constitutional disturbance of a low type. Cystitis may occur in consequence of the increased irrita- tion to which the bladder is subjected. When it sets in it speedily assumes a low form, and is apt to prove fatal by the induction of typhoid symptoms; even if it do not do so, its occurrence is an insuperable obstacle to the further crushing of the stone, and in such cases as these, the best course that could be pursued would be, after getting the patient into as favorable a state as possible, to remove the fragments by lithotomy. Atony of the bladder is one of the most dangerous con- ditions that can occur in lithotrity. This state of things happens usually in elderly people, in whom the urinary organs may appear to be in a peculiarly quiet and favorable condition before the operation, the patient being able to hold his water for six or eight hours, and to bear the injection of ten or twelve ounces of fluid. Under these circumstances the surgeon should be upon his guard, for the danger of this condition is, that the bladder does not possess sufficient contractile power to expel the fragments. These consequently accumulate in the lower fundus, and irritate the mucous membrane, and thus the foundation may be laid for fatal cystitis, which in these cases always assumes a typhoid type. The atony of the bladder appears to arise partly from that natural want of expulsive power, which is not unfrequent in old people, and partly from a kind of paralysis of the organ, induced by the contact of the instruments and the pressure of the fragments; this happened in a patient whom I lithotrized at University College Hospital some years ago, and who died with severe constitutional depression, and with pyemic symptoms. When atony of the bladder has come on, it is essential that the surgeon should rid the patient of the fragments which he is unable to expel. This may sometimes be done by means of the scoop, assisted by washing out the bladder through the double-current catheter, but the safer plan would probably be to get the patient into as good a condition as possible, and then cut him. This I LITHOTOMY AND LITHOTRITY COMPARED. 941 once did in an interesting case under my care at the hospital; the patient, an old man, had been lithotrized by a surgeon out of doors a few weeks before admission, but no fragments had passed; on sounding him, I found a moderate- sized calculus, with what appeared to be a large mass of soft concretion, of the nature of which I was not aware until after its removal; the patient having concealed the fact of his having been lithotrized. On cutting him in the usual way, I removed a lithic acid calculus about as large as a pigeon's egg, and a handful of fragments of another calculus of the same composition, which had been crusted over and matted together by phosphatic deposit. The patient made a very good recovery. Irritation of the kidneys, giving rise to suppression of urine, occasionally occurs. In such cases, cupping the loins, .and the warm hip-bath, would be the proper treatment to pursue. Very considerable constitutional depression occasionally follows the operation of lithotrity, the pulse becoming quick, feeble, and intermitting; the skin hot and dry; and the tongue brown. This condition is apt to prove fatal either directly or by intercurrent visceral mischief; it appears to arise in many cases from causes independent of the operation, or that are called into activity by the shock and slight constitutional disturbance induced by it. This is more especially apt to happen when there is latent disease of the kidneys. In other instances, again, it is more directly dependent on the irritation induced by the operation being the result of the formation of abscess in the neighborhood of the prostate, or around the neck of the bladder; and in other instances, again, from the supervention of unhealthy suppuration in some of the sacculi that are occasionally met with in this organ; — from whatever cause arising, this condition is usually eventually fatal by the supervention of pyemia. COMPARISON BETWEEN LITHOTOMY AND LITHOTRITY Lithotomy and lithotrity differ so entirely from one another in principle and detail, that it is useless to attempt to establish a comparison between the different steps of these two operations. It is, however, a question of very considerable importance and interest to ascertain by which operation a patient can most safely have a calculus removed from his bladder. In determining this point, it is not only necessary to make a comparison between the general results of cases that have been subjected to the two procedures, but more especially to determine those circumstances that influence the result of either operation in particular cases — to determine, in fact, in what cases lithotomy, and in what lithotrity, holds out the best prospect to the patient. It is, I think, in the highest degree unpractical to enter into a discussion as to which should be the general method of treatment in cases of stone. Both operations have been reduced to great simplicity and certainty; but neither should be exclusively practised. It is undoubtedly the duty of the surgeon to make himself familiar with the practice of both, and to adopt that one which promises best in the particular instance with which he has to do. If, however, I were called upon to say which operation I consider most generally applicable, then I should unquestionably answer lithotomy. But yet there can be no doubt that there are many cases in which lithotrity is the preferable method; and in those in which lithotomy or lithotrity may be done with an equal chance of success, the preference should, I think, be given to the crushing over the ^Th^stoStoT'that are before the profession do not represent the true state of the question, so far as a general comparison between the operations is con- cerned For it must be borne in mind that those cases that are lithotrized have invariably been picked cases; whilst lithotomy has been performed on almost all patients as they have presented themselves. It has already been stated 942 STONE IN THE BLADDER. (page 934) that for lithotrity to be successfully done, it is necessary that the stone be of moderate size, single, not too hard, and that the urinary organs be in a healthy state and free from irritation. x\nd this is the state in which most of the cases have been in which crushing has been done. In lithotomy cases, on the other hand, the surgeon has had to contend with all the difficulties of large or multiple calculi, diseased bladders, and bad constitutions. Hence on comparing the statistics of the results of lithotrity with those of lithotomy, we compare the statistics of the results of operations performed under the most favorable circumstances on a series of selected cases, with those of cases taken indiscriminately and often presenting most unfavorable conditions. Another cause of uncertainty with regard to the statistics of lithotrity is, that those we possess are chiefly from a professed lithotritist, M. Civiale, the accuracy of which has been denied in a very decided and emphatic manner by many of the leading surgeons in Paris, who have inquired fully into the matter; and the conclusions from which must necessarily be received with much hesi- tation in this country, where it is difficult to arrive at the real truth of the state- ments advanced on either side. If we compare Civiale's statistics of lithotrity with those of lithotomy, as practised by the most skilful surgeons, Cheselden, Liston, and the Norwich ope- rators, we should at once decide in favor of the crushing method; for Civiale states that out of 591 operations he had but 14 deaths, or 1 in 42-2; whilst, as we have seen, the most skilful lithotomists in this country, where the results of the cutting operation have been far more successful than elsewhere, can only boast of such a rate of mortality as 1 in 7-9, or at most in 10. But though the success is thus stated by Civiale to have been great in his own cases, the accu- racy of this statement has been denied by other French surgeons, and it is cer- tainly very different to what has occurred elsewhere. Thus of 162 cases ope- rated upon by lithotrity by various surgeons in Paris, Civiale states that death resulted in 38, and a cure in 100 instances; the results of the remaining cases being unknown, or the cure incomplete. In this country it is impossible to say, even approximately, what the average mortality after lithotrity has been; those surgeons who have had most experience in this operation not having published any account of their cases; but I believe there is a pretty general feeling that in the different London hospitals in which it has been performed, lithotrity has not been a very successful operation. The same remark appears to hold good with regard to the Parisian hospitals; Malgaigne estimates the mortality from lithotrity in those institutions at 1 in 4, while he calculates that of private cases at 1 in 8. The difference between the results of this operation in hospital and private practice can easily be accounted for by the difference in the constitu- tions of the patients, and by their applying for relief in private in a less advanced form of the disease than in hospital practice. We find the same hold good with regard to the results of lithotomy. Thus Mr. Coulson states that Dr. Dudley lost only 1 in 36 of the private patients that he cut; Dr. Mettauer, 1 in 36£; Mr. Martineau, 1 in 42; and Dr. Mott, 1 in 50. These results are fully as favorable as Civiale's statistics of lithotrity, and show the influence that the constitution of the patient, and a proper selection of cases may exercise upon the results of the cutting operation. The only statistics of lithotrity that we at present possess are those given by Sir B. Brodie, as the result of his practice, chiefly on private patients. That eminent surgeon states, that out of 115 cases of lithotrity,—not all, however, on different individuals, the operation having been repeated more than once on several of the patients,—he lost 9. Of these, death was directly attributable to the operation in 5 instances, and in the remaining 4, appeared to be dependent on organic disease, brought into activity by the shock of the operation. Lithotrity, as has already been stated, cannot be applied to all cases of stone, but in many that are unsuited to this operation, lithotomy may be done with LITHOTOMY AND LITHOTRITY COMPARED. 943 success. In some cases, however, no operation can be practised in consequence of serious disease of the genitals, bladder, or kidneys, or of some visceral mis- chief that would necessarily interfere with the performance of any capital ope- ration. The necessity of selecting cases of lithotrity is well instanced by a state- ment that Civiale has given with reference to this point. This dexterous litho- tritist considered that of 838 calculous patients that applied to him during a series of twenty years, only 548 were fit cases for lithotrity, and 290, or more than one-third, were not operated on by this method; of the last 332 cases included in this list, 241 were lithotrized, 1 in 3-6 being considered unfit for that operation. Of the 91 cases not crushed, 28 were cut, and in 8 others litho- trity and lithotomy were combined. Of these 36 cases subjected to lithotomy, M. Civiale lost 18, or exactly one-half. These figures show that lithotrity cannot be considered the general operation for stone; but must, even in the hands of the most dexterous and successful practitioners, be in many instances replaced by the cutting operation. The circumstances that must chiefly determine the surgeon in the selection of the particular operation that is to be performed are, 1st, the age of the patient; 2d, the size and character of the stone, and 3d, the conditions of the urinary organs. 1st, the age of the patient is an important element. As a general rule it may be stated, that it is at the middle and advanced periods of life that lithotrity is most successful, whilst at early ages lithotomy is the preferable operation. The success of lithotrity at advanced periods of life is as good as in middle age, and has been very great in the hands of some surgeons. Thus, Segalas states, that of 14 octogenarians whom he lithotrized he did not lose one; and of 27 septu- agenarians, but two. Lithotomy, on the other hand, is extremely fatal in aged persons. In children, under or about the age of puberty, lithotrity is a difficult operation, though it may be performed even at very early periods; but the small size of the urethra and the restlessness of the child interfere materially with the success of this operation. Lithotomy, on the other hand, is so successful an operation in children, that the surgeon would probably gain nothing by sub- stituting lithotrity for it. Thus, of 35 children under ten, operated on by Cheselden, but one died; and of 58 cases of children operated on at St. Tho- mas's, but one proved fatal, and the average mortality in them is not more than about 1 in 14 cases. Hence, lithotomy, being probably equally safe and far speedier, should be preferred to lithotrity in all cases under about twenty years of age. 2d. The size and character of the stone influence in a very important manner the choice of an operation. Surgeons generally recognize the fact that a small stone is more favorable to lithotrity than a large one, and that the operation should not be undertaken if the calculus exceeds one and a half inch in dia- meter Below one inch in diameter all calculi may be crushed, provided other circumstances are favorable. Much, however, will depend upon their composi- tion. Phosphatic calculi of larger size may even readily be crushed, and thus be got rid of Lithic acid concretions, the fragments of which do not disinte- grate, but split up into sharp and angular spiculae and scales do not, it large, admi of lithotrity. Oxalate of lime calculi occurring as they do chiefly-in young people, comparatively rarely require lithotrity, but, when crushed break ud verv readily, and, as there is usually a co-existing healthy state of the un- narv organs the cases have a favorable issue. Some of the French hthotrizers Le in the habit of breaking up friable phosphatic calculi from fifteen to twenty line o more in diameter; but stones of this size are, I think, usually and more prudently subjected to lithotomy in this country. The existence of several calcuU, even when small, though not a bar, is yet an objection to lithotrity, for rea^sons^aheady^ate ^ ^ ^.^ ^^ ^ ^^ ^ ^^ importance thaQ 944 STONE IN THE BLADDER. the size and character of the stone. As a general rule, it may be stated that the greater the irritability and inflammatory tendency of these parts, the less successful will lithotrity be. The repeated introduction of instruments, how- ever carefully and skilfully conducted, the presence of fragments of calculus and their tendency to impaction or entanglement in the urethra, necessarily dispose to inflammation even in the most favorable cases, and very readily excite it, if there be any tendency to such action existing in the parts. If, however the stone be of small or moderate size, friable, the bladder healthy, and with good contractile power, the urethra capacious, and the patient of sound consti- tution and quiet temperament, the stone may often be broken up and the frao-- ments expelled with remarkably little suffering. In fact, under a combination of favorable circumstances such as these, lithotrity ought unquestionably to be preferred to lithotomy. If, however, the bladder be very irritable, or if the patient's constitution is an excitable one, so that he does not bear the introduction of instruments well; and more particularly if it be found that this local and constitutional sensitive- ness, instead of being blunted by the methodical introduction of sounds or bougies, is rather increased by them; and especially if the stone be of a medium or large size, so that several sittings would be required before the fragments could be expelled,— lithotomy should be had recourse to. The existence of organic disease, however, about the urinary organs, consti- tutes the greatest obstacle to lithotrity, and when extensive must form a com- plete bar to the performance of that operation. It is not easy, however, to determine the amount of local disease that should thus be held to contra-indicate lithotrity. On this point the opinions of surgeons differ much, and it is par- ticularly in the management of these cases that the advantage of that tact and dexterity in the use of the crushing instruments, which habit can alone give, is so well exemplified. Organic disease of the kidneys is a more serious obstacle to lithotrity than to lithotomy, on account of the prolonged nature of the operation, and the greater liability to sympathetic or propagated irritation in these organs, giving rise to purulent nephritis. It is not only by the operation increasing the renal mischief that harm might result, but rather in consequence of the tendency to low and diffuse inflammation, to pyemia, etc. that always co-exists with kidney disease. A chronically inflamed state of the bladder, more particularly if the organ is thickened and fasciculated, so that it will not bear the injection of a few ounces of tepid water, seriously interferes with the success of lithotrity. If the blad- der be sacculated, there will be a still greater risk of an unfavorable result, these sacculi not only retaining fragments of calculus, but also becoming the seats of unhealthy inflammation, in consequence of which typhoid cystitis of a very serious character, followed by pyemic symptoms and metastatic abscesses, may result. In such cases as these, lithotomy offers the only chance to the patient. The existence of a moderate amount of vesical catarrh, if the bladder is other- wise healthy, is no objection to lithotrity. Atony of the bladder is a serious inconvenience, and a great source of danger in lithotrity. It cannot well be positively ascertained, though it may be sus- pected if the patient can hold his water for a great many hours, and can bear without complaint the injection of a large quantity — eight or ten ounces — of fluid, the interior of the bladder feeling large and smooth to the sound. This condition chiefly occurs in old men of feeble habit of body; and, if ascertained, should call for the performance of lithotomy. In encysted calculus, lithotrity is for obvious reasons inadmissible. Moderate enlargement of the prostate, such as is habitually met with in elderly people, does not necessarily prevent the performance of lithotrity, though it undoubtedly complicates the operation and increases its difficulties, RECURRENCE OP CALCULUS. 945 the fragments having a tendency to become lodged in the lower fundus behind the enlarged gland. This more especially happens if the middle lobe is en- larged, and, under these circumstances, though the stone may undoubtedly be crushed, yet the fragments would probably require to be removed by the scoop; the operation would consequently be very tedious and prolonged, and lithotomy would probably be found to answer best. Any inflammatory disease or abscess of the prostate must necessarily prevent the performance of lithotrity. Stricture of the urethra does not prevent the performance of lithotrity, but only retards the operation until the constriction can be properly dilated. Should this, however, not be practicable to the full extent of the urethra, lithotomy on a small staff must be practised. I have said nothing, in this comparison between lithotrity and lithotomy, of the comparative painfulness of the two operations; for, as chloroform may be administered with equal advantage in both sets of cases, there is little difference in this respect, except that perhaps the advantage lies on the side of lithotomy, as being the shorter proceeding. From all that precedes, then, it would appear that useful as lithotrity unques- tionably is in many cases, it cannot be looked upon as a general means of treat- ing stone in the bladder; being only applicable under very favorable circum- stances; and that a large number of cases will always be left in which lithotomy offers the sole means of relief. . Recurrence of calculus after operation may take place from three distinct causes—1st, in consequence of a continuance of the constitutional condition, or diathesis, under the influence of which the calculus was originally formed; 2d, from the descent of a renal calculus; and 3d, from a fragment of calculus having been accidentally left behind. % . Relapse from the first cause is probably not very common, but its occasional occurrence shows the necessity of continuing constitutional treatment adapted to the particular diathesis, after the removal of the calculus from the bladder. It is relapse from this cause that probably occurs in cases of lithotomy, though even in this operation a fragment of calculus may accidentally be broken off durin- extraction, and left behind. Yet such an accident is not very frequent; for if°the calculus happens to be broken during extraction, the fragments, it not completely cleared out of the bladder, will usually be washed away through the wound by the flow of urine. The registers of the Norwich Hospital show 1 relapse in 58 cases; and those of Luneville, 1 in 116 cases of lithotomy ^In^thotrity, on the other hand, relapse is far more common. In the prac- tice of M. Civiale it has occurred about once in every tenth case This must evidently arise from some fragment of calculus having escaped^ detection and beino- left behind, thus constituting a nucleus for a fresh formation. Ihe fre- quency of the occurrence of secondary calculi after lithotrity, even in such pSed hands as M. Civiale's, certainly constitutes an objec ion, to tiua opera tion, and shows the necessity of the surgeon most carefully examnmg the bladder before he pronounces the patient cured; and even then watching him forborne^length o/time, in order to meet the calculus at its first formation, and tolf l^nt^tSnd^Senlu. forming, whether after lithotomy or lithotr tv most surgeons would feel disposed to extract it by the cutting opera- 5oT& iXlT/Lve previously b-P^ ^geon thG T\ M? LiS's dvicTJfeu troughthe'right shle of the perineum on may adopt Mr. Liston s aavice °xity. As this procedure, however, & St ft WtiiathSrr h left hand forcutting and extracting, most surgeons U 7 think prefer either the operation through the site of the old wound Trie' U^eS^tio*. Whatever procedure, however, is adopted, it should 60 946 STONE IN THE BLADDER. be borne in mind that the rectum may have become pretty firmly adherent to the membranous portion of the urethra and the apex of the prostate, in conse- quence of the contraction of the old cicatrices, and may thus be endangered. CALCULUS IN THE FEMALE. Stone is of rare oecurrence in women; in London, certainly, I believe it is not often met with. Thus, South states, that during a period of twenty-three years, 144 males were operated on for stone at St. Thomas's Hospital, and only 2 females. In some districts, however, stone would appear to be more common in women than this:—Thus, according to Mr. Crosse, at the Norwich Hospital, the proportion has been about 1 woman to 19 men. Civiale states, as the result of his researches, that in the North of Italy, the proportion is as 1 to 18; and in France, as about 1 to 22. Calculus in women is most frequently deposited upon foreign bodies, accidentally or purposely introduced into the bladder, such as pins, pieces of pencil, &c. At the University College Hospital we had not had a case of stone in the female for many years until 1855, when three came under my care in the course of a few months. The symptoms of stone in the female closely resemble those that occur in the male, and its presence may usually be easily detected by means of a short and nearly straight sound, or a female catheter. It is often simulated very closely by the irritation occasioned by a vascular urethral tumor, or by an irritable bladder, but exploration of the viscus will always determine the diagnosis. Calculus in the female bladder, if allowed to remain unrelieved, will not only occasion the various morbid conditions in the urinary organs^ that have been described as following the long-continued presence of stone in the male, but will give rise to diseased states peculiar to the female. Thus the stone may be spontaneously discharged through the urethra: if of small size, without any bad results following; but if large, by a process of ulceration, in consequence of which permanent incontinence of urine will remain; or it may slough through into the vagina; or lastly, it might offer a serious obstacle during parturition to the descent of the foetal head, when if it could not be pushed aside to be dealt with afterwards, it must be cut out or craniotomy be performed. A stone may be extracted from the female bladder by one of three methods: 1st, lithectasy, through a dilated urethra; 2d, by lithotomy; 3d, by lithotrity. These different operations cannot be employed indiscriminately, but each one is more especially adapted to certain kinds of calculus. 1st. Lithectasy may be performed in two ways—either by simply dilating the urethra by means of a sponge tent or dilator, or else by incising the mucous membrane at the same time that the canal is being expanded. a. Simple dilatation of the urethra may be effected quickly by the mtroduc- tion of a tent of compressed sponge, or a three-bladed dilator which is rapidly screwed up. In this way in from two hours to a few minutes the canal may be easily dilated sufficiently to admit of the introduction of a pair of forceps, and the extraction of a calculus of moderate size. Some surgeons prefer a slow process of dilatation, continued through many hours; but this appears to me to possess no advantage over the more rapid expansion, and has the very decided disadvantage of prolonging the patient's sufferings. The plan that I have adopted with most success is to introduce a sponge tent two hours before the intended extraction, and then, when the patient is under chloroform, to dilate the urethra to the required extent, with a two or three bladed dilator. |3. Incision may be employed conjointly with dilatation, in order to prevent injurious stretching of the urethra, and consequent laceration of its mucous membrane. The incisions recommended with this view should be made after the urethra has been dilated to some extent; a probe-pointed bistoury being in- LITHOTOMY AND LITHOTRITY IN THE FEMALE. 947 troduced by the side of the canal, and the mucous membrane divided. Brodie makes an incision directly upwards, Liston downwards and outwards on either side; on the whole, I think, the best direction for the incisions, as more space may thus be obtained. By dilatation, either alone or with incisions of the mucous membrane, small stones may readily be extracted; but in the removal of moderate-sized calculi, the great objection to this operation is the liability to incontinence of urine re- sulting from it. It is difficult to say to what extent the urethra may be dilated without incontinence resulting; this must necessarily vary in different individ- uals. It certainly can be expanded sufficiently to admit of the introduction of the index finger, and to allow of the extraction of a stone eight or ten lines in diameter, without any evil resulting. The incontinence of urine that may be left after the removal of larger calculi than this may not be by any means com- plete ; but a weakened state of the sphincter of the bladder results, so that the patient cannot hold her water for more than an hour or two at the most. 2d. Lithotomy in the female may be performed in a variety of ways. There are, however, only two modes of practising this operation that appear to me to deserve serious attention, viz., the supra-pubic and vaginal. The supra-pubic or high operation in women differs in no very material respect from the same procedure in men; except that it requires additional care in consequence of the difficulty there is in causing the female bladder to retain a sufficient quantity of urine to make the viscus rise sufficiently above the pubes. The extraction of the stone is easy, as it can be raised into the grasp of the forceps by being pushed up from the vagina. Vaginal lithotomy is an operation easy of performance. It may be practised by passing a straight grooved staff into the bladder, pressing the end wett down against the anterior wall of the vagina, and fixing it there with the left index- finger. A scalpel is then pushed through the anterior wall of the vagina and inferior fundus of the bladder into the groove in the staff, which it is made to enter just behind the urethra, and is then run backwards for about 1£ inch; through the aperture thus made the forceps are passed, and the stone extracted. This operation is necessarily followed by a yesico-vaginal fistula, which will be required to be closed by a subsequent plastic procedure. Of these two methods the high operation is, I think, the preferable. With care, there would be but little risk of injuring the peritoneum, and the chance of urinary infiltration, which is a serious objection in the male, may be prevented in the female by the introduction of a syphon catheter into the urethra. The vaginal operation, though easier of performance, is open to the objection of leavino- a permanent urinary fistula. It may, however, be the only alternative. In a case recently under my care, I extracted a calculus measuring eight inches by six in circumference, from the bladder of a young woman, by this method. The stone havino- by its size offered so serious an obstacle to the descent ot the foetal head during parturition, that craniotomy had been rendered necessary; the anterior vaginal wall had been a good deal bruised, and I feared that sloughing of it might take place, hence I extracted the stone by the vaginal ^M Lithotrity in the female requires to be practised on the same principles as in "the male. The details of the operation differ, however in some important naviculars The chief difficulty in the performance of the operation in the frmalP consists in causing the bladder to retain urine or water that is injected f„To t In consequence of this there is not only great difficulty in seizing the tone the bladderqc0llapSing and falling into folds around it, but also danger finVrin^ the mucous membrane with the lithotrite. In order to cause he bidder toVetain the necessary quantity of urine, the pelvis must be well tilted up and the urethra compressed against the lithotrite. It is well not to dilate 948 DISEASES OF THE PENIS AND SCROTUM. the urethra before the introduction of the instrument, as the incontinence is thereby increased. The ordinary male lithotrite is not a very convenient instrument to use in the female bladder, the handle being awkwardly long. This is especially the case in female children. Hence I have found it convenient to have a shorter instrument constructed, with which it is far more easy to manipulate in the female bladder. If urine or water cannot be retained, the calculus may more safely be seized and crushed by means of a small and strong-bladed pair of for- ceps; or if the stone be larger, a crushing instrument, made of the shape of that depicted (fig. 384), but smaller and lighter. After the stone has been crushed, the urethra (unless this has previously been done) may be dilated by means of the two-bladed instrument to a moderate degree, and the larger fragments removed by means of a pair of slender for- ceps. The shortness and wide capacity of the female urethra will readily allow of the escape of the detritus. For all calculi in the female bladder, except those of the very largest size, this operation is the most applicable. By it the stone may be removed piece- meal as it were, without the necessity of dilating the urethra to such a degree as to incur the risk of incontinence of urine resulting. Lithotrity may be had recourse to at all ages, in the very young as well as the old; I have crushed and successfully removed a large calculus in a child three and a-half years of age. Although the urethra of a female child is not very dilatable, yet it can readily, by means of a sponge tent, be enlarged sufficiently to admit a from 11 to 12 lithotrite. CHAPTER LIX. DISEASES OF THE PENIS AND SCROTUM. The penis is liable to certain malformations. Thus it occasionally happens that there is an arrest of union in the mesial line, so that a slit or fissure is left communicating with the urethra. This gap commonly occurs on the under surface of the organ, constituting hypospadias, and is confined to the glans and anterior part of the penis, though it occasionally extends backwards to the root of the organ, and then may be associated with some of those kinds of malforma- tion that are erroneously considered as examples of herma- Fig. 397. phroditism. These conditions are mostly incurable, though plastic proceedings have occasionally been devised for their relief. The upper surface of the penis is less frequently fissured; only, I believe, in cases of extroversion of the bladder. This condition, termed epispadias, may be looked upon as incurable. The prepuce is not unfrequently the seat of malformation or disease. That condition of it in which it is so much elongated that it extends beyond and covers in the glans, and at the same time so much contracted that it prevents the proper exposure of this portion of the organ, is termed phymosis. This may be either congenital, or acquired, as the result of inflammation or disease. In the congenital phymosis the penis is usually somewhat atrophied, and the development of the glans prevented by the pressure of the PHYMOSIS. — CIRCUMCISION. 949 Fig. 398. narrow prepuce. In the majority of cases this condition is simply a source of inconvenience, but it may become a source of disease from the retention of the sebaceous secretion of the part, setting up irritation and repeated attacks of in- flammation (fig. 397). Congenital phymosis especially becomes a source of inconvenience if any gonorrheal or venereal disease is contracted, as it renders the exposure of the diseased part difficult or impossible, and interferes with the necessary treatment. Phymosis that is acquired has usually resulted from repeated attacks of inflam- mation, or of specific disease in the part, giving rise to solid oedema, or false hypertrophy of the prepuce. The treatment of phymosis, when not congenital, must be conducted in accord- ance with its cause; thus, if resulting from inflammation, that must be subdued ; if from venereal disease, that must be remedied, when perhaps the contraction and elongation will gradually subside. If, however, the phymosis be congenital, or if it be acquired, but permanent, it must be subjected to operation, and indeed, I think, that all cases of congenital phymosis in children should be operated upon with the view of" preserving the health and cleanliness of the parts in after-life. Operations for phymosis may be conducted on two plans; the elongated and con- tracted prepuce may be slit up, or circumcision may be performed. Slitting up of the prepuce, whether upon its upper or under surface, is always, I think, an objec- tionable procedure, leaving the prepuce of its abnormal length, and more or less- fissured and knotted. In all cases I prefer circum- cision, as the simplest and speediest operation, and as leaving the most satisfactory rpmilt" Circumcision may most conveniently be performed in the following way (fig. 398) : —The surgeon draws the elongated prepuce slightly forwards, until that portion of it which corresponds to the back of the glans is brought just in front of that structure. He then seizes the projecting prepuce with a pair of nar- row-bladed polypus-forceps, which he gives to an assist- ant, who must hold them tightly. With one sweep of the bistoury he cuts off all that portion of integument which projects beyond the forceps, which are then taken away. It will now be found that he has only re- moved a circle of skin, but that the mucous membrane linino- it, still tightly embraces the glans; this he slits up, by introducing the point of a pair of scissors at the preputial orifice; and then, trimming off the angles of the flaps of mucous membrane and snipping across the frenum, he turns back the mucous membrane, and attaches it to the edge of the cutaneous incision by five points of suture, two on Fig. 399. each side and one at the frenum. Before introducing 950 DISEASES OF THE PENIS AND SCROTUM. these he will generally find it necessary to ligature a small artery on either side of the penis, and sometimes one in the frenum. Union readily takes place by simple dressing, and a very narrow line of cicatrix is left by which the patient is by no means inconvenienced. In some cases, I have found adhesions between the prepuce and the glans which require to be dissected through, but no incon- venience results from this slight addition to the operation. If sloughing of the prepuce have occurred, allowing the glans to protrude as in fig. 399, circumcision must be practised. PARAPHYMOSIS. In paraphymosis the prepuce has been forcibly drawn back behind the glans, which becomes strangled by the pressure exercised by the preputial orifice, so that the parts cannot be replaced in proper relation to one another (fig. 400). This accident principally occurs in Fig. 400. boys, or in individuals who have natu- rally got a tight prepuce, and who on uncovering the glans find it difficult to get this part of the organ back again. This difficulty is speedily and greatly increased by the swelling from conges- tion that is set up in the constricted glans. The treatment of this condition is sufficiently simple. The surgeon should first try to reduce the swollen organ. He may often succeed in doing this by seizing the body of the penis between the index and middle fingers of either hand, and then endeavoring to draw the prepuce forwards, at the same time that he compresses the glans between the two thumbs and pushes it back (fig. 401). Should reductions not be effected in this way, the constricted and strangulating pre- putial orifice must be divided. In doing this, the surgeon will observe that the glans is separated from the body of the penis by a deep and narrow sulcus, which is especially evident on the upper part of the organ (fig. 400, a). This sulcus, which is overlapped on one side by the glans and on the other by a fold of in- tegument, corresponds to the inner mar- gin of the preputial orifice, and it is by the division of this, in which the stricture is situated, that immediate relief will be given. This operation may readily be done by drawing the glans forwards, then passing the point of a narrow-bladed scal- pel into the sulcus on the dorsum of the penis, and making a perpendicular inci- sion about one-third of an inch in length through the integuments at the bottom of the groove directly across it. In consequence of the great stretching of the parts, the incision will immediately gape widely, so that instead of being longi- tudinal it will appear to be transverse, and then reduction of the glans may readily be effected. Fig. 401. C^ r BALANITIS.— CANCER PENIS. 951 BALANITIS. Inflammation of the prepuce commonly occurs as the result of local irritation not unfrequently set up by a gonorrhea. When confined to the prepuce, and constituting balanitis, that structure is much swollen, infiltrated, and reddened and while the inflammation lasts, continues in a state of phymosis. When the mucous membrane of the glans is affected as well, constituting posthitis there is a good deal of irritation and smarting, together with muco-purulent discharge. The disease requires to be treated on ordinary antiphlogistic principles; the continued application of lead lotion, with the internal administration of salines will generally remove it; but in many instances the most effectual plan will be found to consist in rapidly sweeping the inflamed surfaces with a stick of nitrate of silver passed down between them on one side of the frenum, and carried round to the opposite side. Herpes of the glans and prepuce is characterized by the formation of small vesicles or excoriated points upon the mucous membrane of this region, attended by much smarting and itching, and chiefly occur- ring in persons of a gouty habit of body, with an irritable mucous membrane. This slight affection is often very rebellious to treatment. In many in- stances, local means alone will not suffice; for though relief may be obtained by powdering the part with the oxide of zinc, by using slightly astrin- gent and cooling lotions, yet no permanent benefit will be derived unless constitutional irritation be removed by treatment of a cooling or alterative character, modified according to the circumstances of the case. Hypertrophy of the prepuce not unfrequently oc- curs as the result of chronic irritation or disease; it is usually of limited extent, and requires no spe- cial interference on the part of the surgeon; but in some instances it may become so extensive as to demand operative interference. Thus Vidal has related and figured a case that had attained such an enormous size, that the organ reached to below the knees, and was as large as a thigh. This monstrous growth was successfully excised. Warts on the penis have already been described. They may attain a very large size, as in fig. 402, and are best treated by excision. CANCER OF THE PENIS. The penis is liable to cancerous disease, which commonly assumes the schir- rhous form, and usually springs from the sulcus behind the glans, and may thence invade the neighboring portion of the organ or the prepuce. It may assume the primary form either of a tubercle, of infiltrated cancer of the glans, or of a cancroid ulcer. It has been supposed, and with some show of reason, that congenital phymosis predisposes to the affection, probably by confining the secretions, and thus keeping up irritation of the part. Hey found that of 12 patients with this disease, who came under his observation, 9 had congenital nhvmosis • and Travers states that the Jews who are circumcised are seldom subiect to this affection. But as they are a limited community in this country, and as the disease is rare, we cannot draw any conclusive inference from this observation The affection, however, can occur in individuals who have not suffered from phymosis; of this we have had several instances at the University College Hospital. 952 DISEASES OF THE PENIS AND SCROTUM. The progress of the disease is usually somewhat slow; the organ enlarging and hardening, without any very great degree of pain. If it form as a tubercle, it may, after a time, give rise to a large irregular and sprouting mass, having a granular fungous appearance, bleeding with much fetid discharge, enveloping and at last implicating the glans, prepuce, &c. In other cases it may commence as a hard scirrhous mass, of a pale reddish-white color, situated on the glans, or between the prepuce and the glans. This increases in size, at last cracks, and allows a serous fetid discharge to exude. Ulceration then rapidly takes place. Sometimes this scirrhus appears to be very distinctly localized; but after its removal it will always present the character of an infiltrated cancer. It is, I believe, always primarily situated at the anterior extremity of the penis, not occurring in the body of the organ, except as a secondary deposit. Cancer of the penis requires to be diagnosed from warts of a fungoid charac- ter. This may usually be done readily enough by comparing the indurated state of the malignant, with the soft and lax condition of the non-malignant affection. From chancrous induration, the history of the case and the way in which it is influenced by treatment, will enable the surgeon to effect a diagnosis. In in- durated plastic effusions into the corpus spongiosum, no pain is experienced, and the disease remains in a stationary condition. The treatment of cancer of the penis must be conducted on the principles that guide us in the malignant affections wherever situated, viz.: to remove the dis- eased organ, provided the affection is localized, the glands not implicated, and the constitution not poisoned. In the case of cancer of the penis, this may readily be done by an operation that is simple in its execution and devoid of danger. In many cases, doubtless, a return may take place, and that speedily, either in the part itself or in the neighboring lymphatic glands; but yet, even if this occur, it is clearly the duty of the surgeon to rid the patient of a loath- some disease, and to put him in a state of comparative comfort for some months; the more so, as there can be no doubt that, in some instances, the disease may be entirely extirpated from the system, evincing no tendency to return. In some of Hey's cases, which continued under his observation, there was no recur- rence of the disease for several years; and I have lately seen a gentleman who had his penis amputated for cancer more than twenty years ago, and in whom no return has taken place. The fact is, that we see and hear of those cases in which a recurrence takes place; but those patients who remain free from a re- turn of the infection, do not divulge their infirmity; and it is exceedingly rare in hospital practice to find a patient come back with recurrent cancer in the stump of the penis or the lymphatic glands, which he would certainly do if relapse took place. In those cases in which the operation is not successful, it generally happens that the disease has already implicated the lymphatic glands. Amputation of the penis must always be performed towards the root of the organ, so as to get well clear of the disease; at the same time care must be taken not to remove it too near the pubes, lest the stump retract under that bone. The operation may readily be done by the surgeon putting the penis upon the stretch, drawing the integument well forward, and then severing the organ at one stroke of the bistoury. It is well not to leave too much skin, lest the flap, falling over the face of the stump, makes the search for any bleeding vessels somewhat difficult, and afterwards may pucker inconveniently. There are usually five arteries requiring ligature; the dorsales penis, one in each corpus cavernosum, and one in the septum. In securing these, trouble is not unfre- quently experienced in consequence of the retraction of the stump that is left. The liability to this, however, is lessened by passing a hook through the root of the organ before the operation is commenced, or by directing the assistant to hold it firmly between the fingers, and then to prevent the retraction of the stump, which may otherwise draw back and be buried almost in the perineum. Should it do so and oozing continue, a female catheter must be passed into the DISEASES OF THE SCROTUM. 953 urethra and a firm compress applied with a *]" bandage. During and after cicatrization, the urethral orifice has a tendency to contract. This may, how- ever, be prevented by drawing forwards the mucous membrane, making four cuts in it with a pair of scissors, and then stitching it to the edge of the cut skin. If the amputation be performed high up, this may be somewhat difficult, and then it may be safer to introduce an elastic catheter before the operation, to perform the amputation upon this, and to leave it in during cicatrization. After the operation, the urine will not be projected forwards, but always passes directly downwards between the legs. Any inconvenience in this respect may best be avoided by adopting Ambrose Pare's advice of adapting a funnel, which may be made of metal or ivory, to the pubes over the stump, and thus carrying the urine clear of the person. DISEASES OF THE SCROTUM. Inflammatory edema of the scrotum is an erysipeloid inflammation of this reo-ion, which derives its chief peculiarity from the circumstances of its giving rise to great effusion into, and swelling of the cellular tissue, with a tendency to the rapid formation of slough in it, by which the integument may likewise become affected to such an extent that the testes and cords speedily become denuded. This disease usually originates from some local source of irritation, as fissures, cracks, or urinary extravasation. The treatment consists in elevating the scrotum, fomenting it well, and making early and free incisions into it, more particularly at the posterior and dependent parts, with the view of relieving the tension to which the tissue is subjected by the effusion into its cells; and thus preventing the liability to sloughing. Should this occur, the case must be treated on ordinary principles, when cicatrization will speedily ensue, however extensive the denudation of parts may be; the constitutional management must always be conducted in accordance with those principles laid down in the first division of this work, and with especial atten- tion to the maintenance of the patient's strength. Hypertrophy of the scrotum seldom occurs in this country, though Mr. Liston once had occasion to remove such a mass weighing 44 lbs.; but in some tropical regions more particularly India and China, it is of frequent occurrence, and may eo on until it attain an enormous bulk, forming a tumor nearly as large as the trunk, and perhaps weighing 60 or 70 lbs. These enormous growths are of a simple character, and constitute the disease termed elephantiasis of the scrotum. Tumors of this kind necessarily require extirpation, and in performing such onerations there are two points that demand special attention: the first is the nrese ^ on of the penis and testes, which will usually be found buried towards the upper part of the mass, and which may be done if the tumor is of small £ and thesecond is to endeavor to prevent the hemorrhage Deing of too refuse^a character. With this view the operation ought not on£ to he> per formed as rapidly as possible, but the suggestion made by Mr. D. t errall ot eleXrthe turner above the level of the body, for some time before its removal so Is to empty it of its blood, may be advantageously adopted. If the growth be very Ztfit will be better not to make any attempt at saving the testes or nenls which could only be dissected out by a long and tedmus operation, in the penis, ^1^h.C°hUthere would be danger of the patient dying from hemorrhage. ^^^S^dL^e occasionally affects the scrotum, and as it prin- Cancerous or Cd'1L. sweeT)erg it has been appropriately enough termed cipally ooou^ ohmney-Bwe per. i ^P ^ ^ ^ tZTSn* in th? folds of the scrottTm, and is a very common form of ™„ 1 dise°aseD It commonly commences as a tubercle or wart, which at last ■ ZTt crack or ulcerate, presenting the ordinary characters of cancerous ulceration After a time the inguinal and pelvic glands will be seen to be 954 DISEASES OF THE TESTES AND CORD. affected, and the patient, if deprived of his covering of soot, will be found to be cachectic looking. The treatment consists in excising widely the diseased portion of the scrotum, provided the inguinal glands be not involved, or the patient's constitution poisoned. The disease has a great tendency to return, and it is seldom that the patient long escapes with life when once he has been affected by it. CHAPTER LX. DISEASES OF THE TESTES AND CORD. MALPOSITION OF THE TESTIS. The testis may be situated in the inguinal canal, not having properly descended into the scrotum, and then may become inflamed, as will presently be noticed; or it may become affected in this situation by malignant disease, rendering its extirpation necessary. The testis may be met with in other abnormal situations; thus, some time ago I saw a case in which one of these organs was situated in the perineum close by the anus, and cases have occurred in which they have been met with in the interior of the pelvis. The organ may sometimes be turned hindside forwards, being retroverted, so that the epididymis is placed in front. In a case of this kind that I had an opportunity of examining after death a few years ago, the epididymis and vas deferens were considerably larger than natural. If a hydrocele form in such a case it will be seated behind the testis. NEURALGIA TESTIS. A painful or irritable condition of the testicle may occur without any actual disease of the organ; the pain being either seated in the epididymis, which is the part naturally most tender, in the body of the testis, or stretching along the cord to the loins and groins. It is usually paroxysmal, and is accompanied by great tenderness, and commonly by some fulness of the organ, which feels soft and flaccid; but it is difficult to make a proper examination on account of the agony that is induced by touching the part. This disease chiefly occurs in young men of a nervous and excitable temperament, and is frequently associated with great mental disquietude and despondency, often amounting to a suicidal tendency. The causes are obscure; in many cases the disease appears to be connected with a neuralgic temperament, but in others it is associated with some dyspeptic disorder, or may be dependent upon local irritation; thus external piles, or the pressure of a varicocele, will often give rise to it. The disease is usually of a very chronic character. In some instances, how- ever, it ceases spontaneously, after having lasted for weeks or months. When dependent upon constitutional causes, the treatment is extremely unsatisfactory. The administration of tonics, such as iron, zinc, or quinine, the local application of sedatives, as of atropine ointment, or the tincture of aconite, may be of ser- vice. In other cases, cold bathing or douching will be beneficial, and in all, keeping the part supported with a suspensory bandage will be advantageous. In the event of there being any local irritation, that should be removed; thus I INFLAMMATION OF THE TESTIS. 955 have known the disease cease after the excision of external piles; and when it is connected with varicocele, proper measures must be adopted for the relief of that affection. In extreme cases, Sir A. Cooper recommends castration; but such a proceeding is altogether unjustifiable in a disease that is either constitu- tional or dependent on local causes readily removable. INFLAMMATION OF THE TESTIS. Inflammation of the testicle, considering the organ as a whole, may be of two distinct kinds, varying as to seat and as to cause. Thus it may be seated in the body of the organ, constituting orchitis, or the epididymis may alone be affected. As to cause, it may be gonorrheal or not. The seat of the inflammation, at the commencement of the disease, depends greatly upon whether its cause is seated in the urinary passages or not. Irrita- tion in any part of the urethra, whether occasioned by the passage of instru- ments, the lodgment of calculi, or the existence of gonorrheal inflammation, usually causes the epididymis to be primarily affected, and the body of the oro-an to be inflamed in a secondary manner. When, on the other hand, the inflammation comes on from injuries, blows, strains, or other causes acting gene- rally, the body of the testis is usually first affected. To all this, however, excep- tions will often occur, and orchitis may supervene as the result of gonorrhea, or epididymitis, from a blow; the orchitis in such cases being in all probability a kind of constitutional affection, intimately associated with inflammation of other fibrous tissues, especially with gonorrheal rheumatism; the inflammation of the epididymis, arising from gonorrhea or other irritation of the urinary passages, appearing to result from direct extension of morbid action along the vas deferens. The symptoms necessarily vary to a certain extent, not only according as the disease is of an acute or chronic character, but as it primarily affects the body of the testis or the epididymis. When commencing in the latter structure it is the inferior globus that is commonly first affected, which becomes swollen, hard, and tender. The disease may be confined throughout to this part, but most frequently it invades the whole of the organ, which becomes uniformly enlarged and somewhat ovoid, frequently accompanied by a good deal of effusion into the tunica vaginalis, then constituting the acute hydrocele of Velpeau. As the inflammation subsides, the different characters presented by the enlargement of the two constituents of the organ again become apparent. The swelling is therefore due partly to general enlargement of the organ, but in some cases to inflammatory effusion into the tunica vaginalis, which may either be of a purely serous, or partly of a plastic character. The pain is always very severe, with much tenderness and a sensation ot weio-ht, and commonly extends up the cord into the groin and loin It is gene- rally oreatest when the body of the testis is affected, owing probably to the enveloping fibrous tunic preventing the expansion of the organ. Hence it 1S often spasmodic and paroxysmal, extending up the course of the cord, lhere is usually a good deal of swelling and redness of the scrotum, with turgescence of the scrotll veins, and a congested state of the cord, with sharp pyrexia, "^^S^^SS^^^e testis first resumes its normal charac- ter and shape, the epididymis often continuing hardened and enlarged for a considerable period. In fact, the induration that forms in the epididymis may ssum" aomeXt permanent character, owing to the effusion of plastic matter hitoTt! leaving a hardened mass, and implicating the whole or a portion of its ^Sutac1™orchitis usually comes on with the same symptoms, though in a less markedI form than in the acute variety. The swelling, however, is considerable, 956 DISEASES OF THE TESTIS AND CORD. though of a softer kind. When the disease is chronic, the testis often becomes permanently enlarged and hardened, assuming an oval shape, being smooth, heavy, and uniformly expanded, with a sensation of weight, dragging and severe pain, and a good deal of tenderness on pressure. This form of orchitis occa- sionally occurs in old people. The treatment of inflamed testicle, whether local or constitutional, is essen- tially antiphlogistic. Blood should be abstracted from the part by puncturing the veins of the scrotum, a far better method than applying leeches, the bites of which are apt to become irritated. This little operation may be very effectu- ally done by directing the patient to stand up and to foment the scrotum for a few minutes with a hot sponge, so as to distend the veins; these may then be punctured at various points with a fine lancet, and the parts well fomented after- wards, so as to encourage the flow of blood. In this way six or eight ounces may be taken in the course of a few minutes; when enough has escaped, the further flow may be arrested by laying the patient down and elevating the part. The patient should be kept in bed with the testis raised on a small pillow between the thighs, poppy fomentations being diligently had recourse to. If there is much effusion into the tunica vaginalis, constituting acute hydrocele, relief may be afforded by puncturing this sac with the point of the lancet. The constitutional treatment during the acute stage consists in the adminis- tration of salines and antimony, with henbane in full doses, so as to give an ape- rient, a diaphoretic, and a sedative together; when this begins to act, great relief is usually afforded. As the inflammation subsides, the treatment must be changed. When there is merely a swelling and hardness left, with but little pain or tenderness, the testis may advantageously be strapped with adhesive plaster, so as to give good support and to promote absorption of plastic matter. Fricke of Hamburg has strongly recommended strapping in the acute stage, but I cannot say that I have ever seen any advantage derived from it at this period of the disease, though I have many times seen it tried; it has usually appeared to me to increase, and sometimes very considerably, the pain in the part and the general uneasiness. In subacute orchitis much benefit is usually derived by a short course of Do- ver's powder and calomel, with early strapping of the testis. When the organ has become enlarged and indurated, as the result of chronic inflammation, it may be advantageously strapped, either with simple plaster or with one com- posed of equal parts of the Emplast. Ammoniaci cum Hydrargyro and soap- plaster; mercury in small doses, more especially the bichloride, being continued for some length of time, until the plastic matter is absorbed and the hardness disappears. In strapping a testicle, the scrotum should be shaved, and then drawn tightly upwards on the affected side. The surgeon should next pass a long strip of plaster, about an inch broad, above the enlarged testicle and round the corres- ponding side of the scrotum, so as to isolate it, as it were. Another strip is now passed from behind, in a longitudinal direction, over the lower end of the testis, and upwards upon the anterior part of the scrotum; and thus, by a suc- cession of horizontal and vertical strips, neatly overlapping and drawn tightly, the organ is completely enveloped and compressed. Abscess, as the result of inflammation of the testis, is of rare occurrence: sometimes, however, the scrotum inflames at one point, where fluctuation be- comes apparent, with thinned skin and evident signs of suppuration; a puncture should here be made, and the pus let out as soon as formed. Sometimes abscess may occur in another way; inflammation is set up in the tunica albuginea, adhesion takes place between the testis and the scrotum, abscess forms under the fibrous coat, and this giving way, the pus gets vent externally through the HYDROCELE. 957 integuments. Into the aperture that necessarily results, a portion of the secre- ting tissue of the gland sometimes projects, and, becoming inflamed, forms a red, granular, and fungous mass, protruding through and overlapping the edges of the aperture. The treatment of this condition will be considered when we come to speak of the scrofulous testicle. Inflammation of the testis in the inguinal canal may sometimes take place, even in adults, when the organ has not descended through the external ring, giving rise to a train of symptoms of a somewhat puzzling character, and that closely resemble those of strangulated incomplete hernia, with which, however, it must be borne in mind that it may be associated (p. 799). On examination, in these cases, a large, irregular tumor, in some parts hard, in othe*rs soft, very tender to the touch, and occasioning a sickening sensation when pressed, will be found in one of the groins, in the situation of the inguinal canal. There i3 usually a tendency to vomiting, and some constipation, with coliky pains in the abdomen. These symptoms, however, are generally not very persistent, and the constipation readily yields to the administration of purgatives. On examining the scrotum, it will be found that the testis on the affected side is absent, and, on passing the finger into the external ring, the organ can be felt to be lodged in the canal. In consequence of the proximity of the peritoneum to the in- flamed testis, this membrane occasionally becomes involved in the morbid action, and, as the result of the constriction of the tendinous and aponeurotic tissues in this situation, sloughing has occasionally occurred. Either of these condi- tions may lead to a fatal termination. The treatment should be actively antiphlogistic. Leeches must be freely applied over the part, and blood should be taken from the arm if the patient is young and strong; salines with antimony being at *he same time administered, and fomentatidns diligently persevered in. In some cases the inflammation of the testis may extend, or the disease may from the first be limited to the cellular tissue of the cord, giving rise to tumefaction, with a good deal of pain and tenderness along it, and eventually the formation of abscess, accompanied by the usual signs of suppuration. The treatment of such a case must be conducted on ordinary principles — early discharge for the pus being secured. HYDROCELE. By hydrocele is meant an accumulation of serous fluid, formed in connection with the testis or cord. Most frequently the fluid occupies the sac of the tunica vaginalis, constituting a true dropsy of it; in other instances, it appears to be formed in distinct cysts, situated either in connection with the testis, or upon the cord. Hence, hydroceles are commonly divided into those that affect the tunica vaginalis, and the encysted variety. Hydrocele of the tunica vaginalis may occur as the result of acute orchitis the inflammation of the testis causing the effusion of a quantity of limpidflu id into its serous investment. This, however, is not he kind of hydrocele that is commonly met with; the fluid so poured out as the result of active mflamma- Z ^llTbeSoming absorbed as the parts recover their normal condition. The^Xary hydrocele occurs as a chronic disease, without any signs of inflam- LTtiZ nf the testicle or, at most, slight tenderness of that organ. It is most C^Shidividu^^t the middle period of life, and generally in personl of feeble power, or in those of a cachetic or gouty constitution, com- TnCtts^^ - ^y\r ff^wn forms- either the ordinary one, similar to what occurs in adults in i^tSav i constitutes a closed sac filled with fluid; or a less Slo?vS^i"^ the accumulation of fluid in the tunica vaginalis 958 DISEASES OF THE TESTIS AND CORD. communicates, by the persistence of a cavity or canal in the funicular prolonga- tion of the peritoneum investing the cord, with the general cavity of that mem- brane. This form of hydrocele is congenital, and the fluid in it occupies the same position that intestine does in a congenital hernia. It may readily be recognized by the fluid being made to flow back into the general peritoneal cavity, by raising or squeezing the tumor. But although this may be considered to be the true congenital form of hydrocele in infants, the other variety of the disease also occurs in them when but a few days old, and very possibly even at the time of birth. The symptoms of hydrocele are tolerably evident. The disease begins with a degree of swelling and weight about the testis, which may at first be soft, but after a while becomes hard and tense, or it may be so from the very commence- ment. Whatever its original condition, the tumor soon becomes oval or pyriform in shape, being narrowed above, rounded and broad below; it is smooth and uniformly tense and hard, often having a semi-elastic feel. It reaches upwards along the cord, towards the external abdominal ring, which, however, is never invaded by it, and the cord is usually distinctly to be felt above the upper margin of the tumor. Most commonly the size varies from that of a hen's egg to a small cocoa-nut, but sometimes it may attain a considerably greater magni- tude than this, and will then cause much deformity of the parts, as it reaches up close to the external ring, and drags over the penis, causing that organ to be buried in it. The most characteristic sign of hydrocele is its translucency by transmitted light. This may always be detected, by the surgeon grasping the posterior part of the tumor with one hand, so as to put the integuments on the fore part on the stretch, then placing the edge of the other hand along the most prominent part of the swelling, and having a lighted candle held close behind. On making this examination, the tumor will appear transparent; if, however, the walls of the sac be thick, or the fluid dark, the transmission of light through it may not be perceived unless the examination be conducted in a darkened room. We have already seen that the ordinary hydrocele of the tunica vaginalis may vary as to size; it may also differ as to shape; in some cases being globular, in others constricted in the middle, or of an hour-glass shape. The quantity of liquid varies considerably; there is usually from six to twelve or twenty ounces, but I have known a hydrocele contain more than one hundred and twenty ounces. The fluid is generally clear and limpid, and of a straw color; but in very large and old hydroceles it may become of a dark-brownish or chocolate hue, owing to the admixture of disintegrated blood; and will then be found to contain flakes of cholesterine. The sac is usually thin, but in some old cases becomes thick and dense, lined by a kind of false membrane, and divided by septa or bands, occasionally to such an extent as almost to separate it into distinct compartments. When the sac is thick, and the fluid opaque and turbid, there may be considerable difficulty in detecting the translucency. The testis is generally somewhat enlarged, especially about the epididymis, and frequently slightly tender, more particularly in the early stages of the com- plaint. It is almost invariably situated at the posterior part of the sac (fig. 403), but may sometimes be found towards its anterior part. When this is the case, the epididymis will be found turned towards the front, owing to the organ being retroverted. The coverings of a hydrocele are the same as those of testis. Besides the integumental structures, aponeurotic prolongations from the intercolumnar and cremasteric fasciae may be traced over the surface of the swelling (fig. 404). The treatment of hydrocele is divided into the palliative and curative. By the palliative treatment the surgeon simply seeks to relieve the patient of the annoyance induced by the bulk or weight of the tumor; but the curative has for its object the permanent removal of the disease. TREATMENT OF HYDROCELE. 959 The palliative treatment consists in the use of a suspensory bandage and cooling lotion, or of tapping with a fine trochar. These simple means, how- Fia. 403. Fig. 404. ever will sometimes succeed in effecting a radical cure. Thus, m infants it will happen that the application of evaporating and discutient lotions may re- move the effused fluid; and indeed it is seldom that any other plan of treatment than this is required in young children. The best lotion for the purpose con- sists of one composed of SJ of muriate of ammonia, §j of spirits of wine to 5viii of water; with this the scrotum should be kept constantly wetted, and it there be a communication with the peritoneum, a truss should be< kept applied over the external ring. In adults it occasionally happens that simple tapping oT^mOThaSaffeltedaradioal cure. Some years ago a gentleman from Cuba consulted me for a small hydrocele which had been forming for several months I tanped it with a fine trochar, and drew off about five ounces of fluid. Swas foKed by a radical cure. 'This case bears out a remark made by SbB^rodKattLfewinBtenoes in which he had known simple tapping poduce a radical cure occurred in West Indians. This simple operation is not alto^eher however, destitute of danger; I have known an od man die from ffimatonr *dem» of the scrotum after being tapped. After tapping it uZhjr havens that the hydrocele slowly forms again, attaining its former bulk at f Tit fhvdreceto ^precautions are necessary, the principal being In tapping a hydrocelea re P f h gcrotal veins. in the to avoid injuring the test s or ^ ^ back ^ the d ■ majority of caJ^ ^e jesaB troch .f ^ is introduced as it quently altogether out of the Y ^ ^ ^ ^ Qn should be, ty *e ^J.Pd witg his left band, and then pushing the trochar stretch by g^P^f^.^ddllthird in front, carrying the instrument at first into the lower part of its miuaie t , j^ perforated the sac, direct- directly backwards (fig. 405 «), butw soo ^^ ^P^ f^ ^ ^.^ ing its point; upwardsU,n ;• ^^ ^^ wh it may some. 960 DISEASES OF THE TESTIS AND CORD. behind. Before using the trochar, it is well to see that the canula fits closely round the neck of the stylet, and above all that the instrument is not rusty by having been carelessly put aside after Fig. 405. use on a previous occasion. The curative treatment has for its object the excitation of a sufficient degree of inflammation in the tunica vaginalis to restore the lost balance between secre- tion and absorption; but it is not neces- sary that the serous cavity should be obliterated by adhesions between its op- posite sides, though these not unfre- quently take place. The means by which the surgeon sets up this inflammation are either by the introduction of a small seton into the tunica vaginalis, or by throwing a stimulating injection into that cavity after tapping it. Which- ever plan is adopted, a certain amount of inflammation ought to be set up. This is always attended by considerable swelling of the testis, and by the effusion of a fresh quantity of fluid into the tunica vaginalis. As this is absorbed, the part gradually resumes its normal bulk, and the disease will probably not return. In order that the radical cure, in whichever way undertaken, should be safe and efficient, it is necessary, in the first instance, that the disease should have been allowed to get into a chronic condition, more particularly if the hydrocele have been of rapid growth. In order to prevent its attaining too large a size, it will be well to adopt palliative tapping once or twice before attempting the radical cure. Care must also be taken to remove all inflammation and tender- ness about the testis, before having recourse to this means of treatment. If attention be not paid to this, recurrence of the hydrocele will probably ensue. After the proper amount of inflammation has been set up, it will be well to treat the patient as if he were suffering under an ordinary attack of orchitis, con- fining him to bed or to the couch for a few days; indeed, I look upon care in the after-treatment as of very considerable importance in securing a favorable result to the case. The cure by the introduction of a seton, though formerly much employed, is seldom practised at the present day, chiefly on account of the danger of exciting too much inflammation. It may, however, conveniently be had recourse to in the true hydroceles of children, and in some of those cases in which the injection fails, if practised in the manner that will immediately be described. The treatment by injection is the one that is commonly employed; it consists in tapping the tumor in the usual way, and then throwing a sufficient quantity of stimulating fluid into the tunica vaginalis through the canula, so as to excite a proper amount of inflammation in it. The liquids that are employed are generally either port-wine or a solution of the sulphate of zinc of the strength of ^i to ^xii, or most commonly the tincture of iodine. If the port-wine or solution of the sulphate of zinc are employed, a sufficient quantity partly to distend the sac should be injected from an india-rubber bottle or brass syringe that can be adapted to the canula; six or eight ounces are commonly required for this purpose, and it should be allowed to remain in for some minutes before being evacuated. The tincture of iodine, originally introduced by Mr. Martin whilst practising at Calcutta, is now commonly preferred as a more certain and a safer mode of treatment than any other. It is usually sufficient to inject about 31 or ^ii of the pure tincture. It should be left in for a few minutes, in proportion to the RADICAL CURE OF HYDROCELE. 961 amount of pain it occasions, and then allowed to escape. A good deal of in- flammation will usually be set up, on the subsidence of which, the cure will be found to have been effected. Useful as the iodine injection is, it sometimes fails in producing a radical cure of hydrocele; this is attributable to two causes: the first is, that in some cases sufficient inflammation is not set up to induce that condition of the tunica vaginalis which is necessary for a radical cure. It is well known that when a hydrocele is radically cured by injection, it is so, not by any adhesion taking place between the two opposite surfaces of the tunica vaginalis and a consequent obliteration of its cavity, but by the inflammation that is artificially induced, exciting such a modification of this membrane as to restore the balance between the secretion and absorption of the fluid, by which it is naturally lubricated. Now in some cases sufficient inflammation is not induced by the introduction of the irritating fluid, to restore the natural balance between these two functions of the membrane; and the tunica vaginalis gradually fills again after the injec- tion, as it would after the simple operation of tapping. It occasionally happens that the patient may suffer excruciating agony at the time of the injection, from the contact of the stimulating fluid with the surface of the testis, and yet little or no inflammation be excited. The amount of suffering, therefore, at the time of the operation, is by no means proportionate to the amount of consecutive in- flammation likely to be set up. Indeed the reverse would appear to be the case in many instances; and I have often observed that in those cases which progress most steadily to a radical cure, there is but a moderate amount of pain expe- rienced at the time of the injection. There is a second way in which injections would appear to fail; a consider- able amount of inflammation is excited, effusion takes place into the tunica vagi- nalis, which, in the course of three or four days becomes distended to the same size, or nearly so, that it had attained previously to the operation; but this effused fluid, instead of being absorbed by the end of the second or third week, remains unchanged in bulk, or absorption goes on to a certain point, and then seems to be arrested ; the tunica vaginalis remaining distended with a certain quantity of fluid. The proportion of cases in which the iodine injection fails to bring about a radical cure of the hydrocele is variously estimated by different surgeons; thus Mr. Martin states that in India the failures scarcely amount to 1 per cent. Velpeau calculates them at 3 per cent. I am not aware that any statistics of this mode of treatment in this country have been collected; but the general opinion of surgeons would appear to be decidedly in its favor as being the; most successful, as well as the safest plan of treatment that has yet been introduced In this opinion I fully coincide : but yet I think it by no means improbable that the success of the iodine injection in this country might not prove to be quite so great as is generally believed. I have, during the last few years, seen aeon- sidfrable number of cases of simple hydrocele of the tunica vaginalis, both in hospital and private practice, in which a radical cure had not been effected although the iodine injection had been had recourse to by some of the most careful and skilful surgeons of the day as well as by myself.. . There can be no doubt that, as a first remedy, the iodine injection is prefer- able to the seton, in the treatment of hydrocele; but when the injection has Sd and this from no want of care on the part of the surgeon, or of attention the' aftt-treatment of the case, but apparently from insufficien Uj-, action havine been set up in the tunica vaginalis to restore the lost ba ance between Jecretion and absorption in this membrane, the seton will, I think be found to he7themost certain means of accomplishing our object. It is true found to be tne: mos ^ q{ ^ getoQ jt requires h ^^^fj^^a^ofally apt to excite a dangerous amount of in- fla^atfontn S^ tZ of tl scrotum; and these objections are to my 61 962 DISEASES OF THE TESTIS AND CORD. mind sufficiently valid to prevent our employing it as the ordinary treatment for the radical cure of hydrocele. But it must be remembered, that the particular cases to which I am now alluding are those in which ordinary means have proved insufficient to excite proper action, and in which, consequently, it would appear as if a greater amount of irritation could safely be borne. Indeed, nothing is more remarkable than the difference in the intensity of the inflammation that is set up in different individuals by the means that are commonly employed in the treatment of hydrocele. In some cases the most irritating injections may be thrown into the tunica vaginalis, or a seton be drawn through the scrotum and left there for days, not only without giving rise to any injurious inflammation, but without setting up sufficient action to bring about a cure of the disease; whilst in other instances simple tapping may effect a radical cure, or may give rise to such an amount of irritation as to terminate in fatal sloughing of the scrotum. The seton that I employ in these cases is composed of one or two threads of dentists' silk. It may be introduced by means of a nevus needle, the fluid of the hydrocele being allowed to drain away through the punctures thus made; or, far better, by tapping the hydrocele, and then passing a needle, about six inches long armed with the seton, up the canula, to draw it through the upper part of the scrotum, and then removing the canula, and cutting off the needle, to knot the thread loosely (fig. 138). The thread should not be removed until the scrotum swells and becomes red, with some tenderness of the testis and effusion into the tunica vaginalis. When these effects have been produced, it may be cut and withdrawn, and the case treated in the same way as when the radical cure has been attempted by iodine injection, viz., by rest and antiphlo- gistic treatment. The length of time that is necessary for the seton to be left in before sufficient, or even any inflammatory action is produced varies very considerably. In most instances the proper amount of inflammation is excited in from twenty-four to thirty hours; but in other cases it may be left in for ten or twelve days, giving rise to but little inflammation, although a radical cure may result. ENCYSTED HYDROCELE. In this variety of the disease the fluid does not lie in the tunica vaginalis, but is contained in a cyst which projects from the surface of the epididymis or testis, and pushes the serous investment of the gland before it. These cysts are much more frequently found connected with the epididymis, than with the body of the testicle. Indeed, Mr. Curling has pointed out the fact, that small pedunculated cysts about the size of currants, and composed of a fine serous membrane, lined with tesselated epithelium, are very fre- quently found beneath the visceral tunica Fig. 406. vaginalis covering the epididymis. They are very delicate in structure, contain a clear limpid fluid, and are very liable to rup- ture. They are met with at all ages after that of puberty. According to M. Gosselin, after the age of forty, they occur in at least \ two-thirds of the testes examined with this / view. Cysts, such as these, may remain sta- tionary, of small size, and not be detected during life, being merely pathological pheno- mena; they may rupture into the tunica vagi- nalis; or, they may enlarge and become developed into tumors of considerable mag- nitude. The fluid of these cysts possesses the remarkable characteristic discovered by HYDROCELE OF THE CORD. — HEMATOCELE. 963 Mr. Liston, of containing spermatozoa (fig. 406); an observation that has been fully confirmed by many subsequent observers. Though spermatozoa do not always exist in this fluid, yet they are usually met with sometimes in small quan- tities, at others so abundantly as to give a turbid or opalescent appearance. This admixture of spermatozoa, with the clear fluid of the cyst is probably due, as pointed out by Mr. Curling, to the accidental rupture of a seminal duct into an already existing cyst. Spermatozoa have also, but very rarely, been found in the fluid of an ordinary hydrocele of the tunica vaginalis, and then probably their presence was due to the rupture of one of those cysts into the tunica vaginalis. Hence their presence in the fluid of a hydrocele may in most cases be consi- dered as characteristic of the encysted variety of the disease. The symptoms of encysted hydrocele differ in some respects from those pre- sented by the ordinary form of the disease. The tumor of the encysted variety being smaller, more irregular in shape, and not enveloping the testis completely, but being situated behind it, and rather in connection with the epididymis. The treatment consists in injecting the sac with tincture of iodine, or, in incising the tumor and allowing it to granulate from the bottom. The injection by iodine, though successful in some cases, is not so frequently so in this as in the last variety of the disease, but usually deserves a trial; if it fail, the incision of the tumor will always effect a cure. HYDROCELE OF THE CORD. This disease is characterized by the presence of a round or oval tumor, situ- ated on the cord, below or within the inguinal canal. It is smooth, elastic, and if of sufficient size may be semi-transparent on examination by transmitted light. It can be pushed up into the abdomen, but receives no impulse on coughing, and does not alter in size by being steadily compressed. It appears to be formed, in some cases, by the funicular portion of the peritoneal investment of the cord beino- imperfectly closed and consolidated at points; though it is possible that in other instances it arises as a distinct cystic growth. These tumors may occur at all ages, but are chiefly met with in the young, and are not unfrequent amono-st5 children. The obliteration of the cyst is best conducted by passing a seton°through, or making an incision into it, and letting it granulate from the The diffused hydrocele of the spermatic cord consists in the infiltration of it with serous fluid, contained in rather distinct cells, and giving rise to an oval or oblong irregular circumscribed tumor, extending below and into the inguinal canal The treatment consists in the application of blisters, or of counter-irritant plasters; should the disease prove very troublesome, an incision might be made down to and into the swelling, so as to let out the fluid and allow the cyst to become consolidated. HEMATOCELE. Bv hematocele is meant an accumulation of blood in the tunica vaginalis, dis- tending that sac, and compressing the testis. It is of two kinds, traumatic: and spontaneous. The traumatic is the most common form of the disease usually Sin- from a blow on, or a squeeze of the testis by which one °f the veins Sying on the surface of the gland is ruptured and blood poured into th unica vaginalis. It may also arise in tapping a hydrocele from the point of the rechar be ng pushed too directly backwards and puncturing the testis The nontaneons hematocele is a disease of rare occurrence, arising apparently from he rupture of an enlarged spermatic vein into the tunica vaginalis It attains a larZ size and is altogether a more formidable affection than the traumatic hematocele In whatever way occurring, a hematocele slowly but gradually increases in size, until it attains about the magnitude of a duck's egg, or even 964 DISEASES OF THE TESTIS AND CORD. that of a cocoa-nut. It is seldom that it becomes larger than this, but cases are recorded in which these tumors have attained an enormous magnitude. I lately operated in a case in which a spontaneous hematocele had existed for six years; it was as large as a good sized melon, and contained besides about a quart of dark thin blood, a handful of partially decolorized and tough fibrine, the greater portion of which was firmly adherent to the inside of the greatly thickened tunica vaginalis in filamentary and laminated masses, with here and there nodules interspersed. The whole of the interior of the tunica vaginalis closely resembled an aneurismal sac. The fluid contained in the hematocele, when the disease is recent, consists of pure blood, but when of old standing, is of a dark and grumous character, owing to disintegration of the blood corpuscles. It then usually contains an admixture of cholesterine. The blood so effused will continue fluid for years; but at last it may decompose and set up fatal inflammatory mischief; in some rare instances the tumor becomes partly solidified by the deposit of masses of fibrinous coagulum, lining the interior of the tunica vaginalis, which are some- times decolorized and arranged, as in the case just referred to, and in one recorded by Mr. Bowman, in a laminated manner, like the contents of an aneu- rismal sac. The symptoms of a hematocele are generally sufficiently obvious. The occur- rence of the tumor subsequently to a blow, strain, or injury when traumatic, its gradual increase in size, somewhat heavy but semi-elastic feel, its pyriform shape, and the absence of transparency, together with the freedom of the cord above, and the want of impulse in it on coughing, will indicate its true character. The treatment of hematocele must vary with the size and duration of the tumor. When small, recent, and having fluid contents, the surgeon may try the effect of tapping it, when it is possible that after the evacuation of the blood, closure and obliteration of the tunica vaginalis will take place. This happened in a case lately under my care, in which, though the disease had existed for three years, a complete cure followed the operation of tapping. Such simple treatment as this, however, cannot be depended upon; and it usually becomes necessary to lay the sac open, and to get it to contract and to granulate from the bottom, when the obliteration of the cavity of the tunica vaginalis necessarily results. If the tumor were of very large size, Fig. 407. and the tunica vaginalis much thickened, hard- ened and parchment-like, with adherent and laminated fibrine, castration might possibly be required. In the instance to which I have already referred, and which has been figured (fig. 407), this was rendered necessary in conse- quence of these conditions, and was successfully done. Hematocele of the spermatic cord has been ob- served by Pott, Curling, Bowman and others; it is a rare disease, and usually occurs in the form of a tumor of considerable magnitude, sud- denly arising after a strain or some violent exer- tion. It commences in the inguinal canal, and thence extends downwards along the course of the cord, through the abdominal ring into the scrotum, but it does not surround or implicate the testis, which can be felt free and movable at its lowest part. On incising such a tumor as this, a quantity of blood, partly fluid and partly coagulated, has been found, sometimes contained in a cavity, occasioned by the laceration and separation of the tissues of the cord. The most remarkable case of this kind on record, is one related by Mr. Bowman, in which the tumor, after existing for ten years, had attained so enormous a size, that it reached to VARICOCELE. 965 the patella, and was so heavy as to require both hands and a considerable effort to raise it from its bed. In this case, death appears to have resulted from decomposition of the contents of the tumor. In its early stages, hematocele of the cord would run considerable risk of being confounded with an inguinal hernia. The more diffused character of the swelling, however, its irregular feel and semi-fluctuating sensation, might enable the diagnosis to be made. Hematocele of the cord may always be dis- tinguished from an accumlation of blood in the tunica vaginalis, by the testicle not being implicated in the former case, but surrounded by the fluid in the latter instance. The treatment of this disease must consist in incising the tumor, turning out the contents, and allowing the parts to suppurate and granulate. VARICOCELE. Varix or enlargement of the spermatic veins, is a disease that is commonly met with from the age of puberty to about the thirtieth year, seldom commenc- ing later than this. It usually occurs in feeble individuals having the scrotum lax and pendulous, and in some cases appears to have been brought on by vene- real excesses. The spermatic veins, extending as they do from opposite the upper lumbar vertebrse to the plexus pampiniformis, which constitutes the base of the pyramidal tumor formed by a fully developed varicocele, are necessarily subject to considerable outward pressure from the weight of so long a column of blood as that contained within them, to which they may eventually yield, becoming much dilated and tortuous. The left spermatic veins are far more frequently affected than the right, partly owing to their compression by feculent accumulations in the sio-moid flexure of the colon, and partly to the obstacle at the mouth, occa- sioneof by their pouring their contents into the left renal vein, at right angles to the current of blood flowing through that vessel into the vena cava. The rio-ht spermatic veins are rarely affected, and never, I believe, without those on the left side participating in the disease. In these cases of double varicocele the left is almost invariably the most seriously affected, but I have seen excep- tions to this in one or two instances in which the veins on the right side formed the largest tumor. . [A careful study of the anatomy of the parts concerned in varicocele will, we think clearly show, that the frequent occurrence of this disease upon one side of the body, and its comparative rarity upon the other, is not in reality due to the causes ordinarily assigned. As the result of numerous and careful examin- ations of the spermatic veins, upon the dead body, we have shown that at the termination of the right spermatic vein in the vena cava, there is always to be found a well marked valve, previously undescribed, formed by the lining mem- brane of the vein, and sufficient to prevent all regurgitation of blood from the vena cava. No such valve exists upon the left side, at the point where the left spermatic empties into the renal vein # As has been already observed by Nelaton, the true causes of varicocele are as vet unknown. The greater length of the left spermatic vein is trivial, at most but half an inch; and moreover the vein is protected from the pressure of the colon by a species of fibrous arch thrown across it, at the alleged point of pres- ure It must be remembered, also, that the disease most frequently originates between the ages of fifteen and thirty, a period of life during which constipation is noteenerally met with. With regard to the impeded circulation on the left de Nelaton remarks, that the obstacle" fc more fancied than real since the side, iNeiaton ie , .^ contents into the renal vein in a vein from *e testicle curves ^ in ^ ]atter dl WeWh d SSSd^po^SB of verifying the facts stated by the French nn \nd we beHeve that the immunity of the right side from the disease in^^t^aUydae to the presence of the valve, whose existence we have 966 DISEASES OF THE TESTIS AND CORD. pointed out; and that the frequency of the affection on the opposite side is mainly attributable to the absence of any such valvular conformation. We would further state that a similar arrangement exists in the ovarian veins of the female; and in the opportunities we have had of examining the diseases of the veins of the right side, we have always found, either that the valve has been absent altogether, or else imperfect in character.—See American Journal of the Medical Sciences for July, 1856.] The symptoms of varicocele consist of a tumor of pyramidal shape having a knotted or knobbed feel, owing to the irregularly swollen and convoluted condi- tion of the veins, with its base upon the testis and the apex stretching up to the external ring. The swelling increases when the patient stands up, if he takes a deep inspiration, coughs, or makes any violent exertion. Its size varies from slight fulness of the veins to a large mass, several inches in circumference at the base. When the patient lies down it goes up to a certain extent, but imme- diately returns to its former magnitude when he stands up again. It is attended by a sensation of weight and sometimes of pain, which is occasionally very acute, of a severe and neuralgic character, even in the scrotum, the groins, and the loins, more particularly when the tumor is unsupported. This pain is greatly increased on the patient walking or riding; so much so, that in some cases he is almost debarred taking necessary exercise, and is prevented following any active occupation. Debility of the generative organs, with a tendency to seminal emissions, frequently accompany varicocele. The diagnosis of varicocele is always sufficiently easy; its peculiar feel, its broad base and narrow apex, the manner in which it goes up when the patient lies down; and returns again when he stands up, are sufficient to distinguish it from all other scrotal tumors. From inguinal hernia the disease may be distinguished by attention to the test described at page 800. The treatment of varicocele must be conducted with reference to the severity of the symptoms occasioned by it, and the extent of the disease. When, as is usually the case, it gives rise to but slight inconvenience, palliative treatment is fully sufficient; but if, as occasionally happens, the disease is a source of very intense suffering, or tends to the induction of atrophy of the testis, or to generative debility, with much mental disquietude or hypochondriasis, then the surgeon may feel disposed to endeavor to cure the varicocele radically. The palliative treatment of varicocele resolves itself into means of various kinds, having for their object the support of the testis and the diminution of the length, and of the consequent pressure, of the column of blood. This is usually most conveniently done by supporting the scrotum in a well-made sus- pensory bandage, or pressure may be made upon the part, as well as support given, by enclosing the testis in an elastic bag. In other cases, support may be afforded by drawing the lower portion of the scrotum on the affected side through a ring made of soft metal, covered with leather. And with the same object, the excision of the lower portion of the scrotum has been recommended, so that by the contraction of the cicatrix, the testis may be pressed up against the ring, and the cord thus shortened. This plan, however, is somewhat severe, and though it might be attended by temporary benefit, the advantage accruing is not likely to be very continuous. The pressure of the pad of a truss on the spermatic cord, as it issues from the external ring, will break the length of the column of blood in its veins, and may thus be of service in some cases, though many patients cannot bear the irksome pressure of the instrument. In addition to these mechanical means, the part may be braced by cold douching, sea-bathing, and the general strength improved by the administration of iron. The radical cure of varicocele consists in the obliteration of the enlarged veins by compressing and exciting inflammation in them, on the same principle that guides us in the management of varix in other situations. As these TREATMENT OF VARICOCELE. 967 operations cannot be undertaken on the spermatic veins without very consider- able risk of inducing an undue, and perhaps dangerous, amount of inflammation in them, and in the loose cellular structures of the scrotum and cord, they should not be had recourse to, unless the disease be a source of very serious inconvenience and pain to the patient. The operation for the obliteration of the spermatic veins may very conveniently be done by using the ordinary hare- lip pins and twisted suture, as figured at page 472. In introducing the pins behind the veins, care must be taken to separate the plexus from the vas deferens. This is best done by letting the patient lie down so as to empty the vessels, when the vas can be distinguished by its firm and corded feel; this must be carefully drawn to one side, and there held between the finger and thumb of an assistant. The surgeon then passes the pins between it and the veins, and including as little skin as possible, applies the twisted sutures in the usual way. Three pins are usually required. A good deal of redness and swelling of the scrotum usually ensue, but after the removal of the pins at the Fig. 408. end of eight or ten days, all irritation will subside, and the disease be permanently cured. The patient should afterwards wear a suspensory bandage. A very ingenious mode of obliterating the veins has been recommended by Vidal, and which, as it does not induce compression of the skin, and only Fig. 409. Fig. 410. iwuires the introduction of one pin, is attended by less irritation than the former method. It consists in passing a steel or silver pin, having a movable head (fi- 408 a) behind the veins, between them and the vas deferens, in the 968 DISEASES OF THE TESTIS AND CORD. usual way. A fine silver wire is then carried, by means of a needle having a slit to receive it (fig. 408 b), in front of the veins, but underneath the integu- ments, being introduced and carried out through the same apertures by which the pin is passed. In this way the plexus of vessels lies between the pin behind and the silver wire in front (fig. 409). The point of the pin having now been removed, compression is made by twisting the ends of the wire round either end of the pin, and is gradually increased by the surgeon every day rolling up the pin so as to twist another turn or two of the wire round it. In this way the veins are not only compressed but rolled up and shortened, and the process is carried on usually for eight or ten days, until they are obliterated by plastic deposit, without being necessarily cut through (fig. 410). Vidal speaks very favorably of this plan, not only as effecting the obliteration of the veins with less risk of inflammation of the scrotum than attends the other method, but as leaving a better result; and I can corroborate his statement, as I have of late employed this practice in several cases with very excellent results. Nelaton has proposed to obliterate the veins of the testis by applying the " Vienna paste" in a grooved pair of forceps across the neck of the scrotum, taking care to isolate the vas deferens. Inflammation is thus excited, and this extending to the veins these vessels become plugged. TUMORS OF THE TESTIS. All solid tumors of the testicle are classed together under the generic term of sarcocele, and when these are conjoined with fluid accumulations in the tunica vaginalis, are termed hydro-sarcocele. Sarcocele is usually divided into the simple, the syphilitic, the tuberculous, the cystic, and the malignant: which, indeed, Comprise so many distinct diseases of the testis, requiring separate study. 1st. Simple sarcocele is a chronic enlargement of the testis, resulting from inflammatory mischief in the organ. A testicle affected by this disease feels hard, smooth, solid, though perhaps slightly elastic at points, is ovoid in shape, and usually about as large as a duck's egg. It is heavy, and but slightly painful. The cord is usually somewhat thickened, and, as well as the groin, is the seat of pain of a dragging character. The tunica vaginalis not unfrequently contains serous fluid lying in front of and obscuring the tumor of the testis, constituting the affection termed hydro-sarcocele. The disease can usually be distinctly attri- buted to a blow, squeeze, or other injury, by which inflammation had been excited in the organ. The scrotum is always healthy. On making a section of a testicle thus diseased, it will be found to be com- posed of a quantity of firm and hard bluish-grey fibro-plastic matter, effused within the organ and between the tubuli, and also surrounding the gland, often in a series of solid and very firm glistening layers. In the midst of this, opaque yellow spots or masses, cutting smooth and firm, will be seen. These have been mistaken for tubercles, but are in reality masses of plastic deposit that have undergone fatty degeneration. In the treatment of this disease, strapping and the administration of an alter- ative course of the bichloride may be tried. If the testis do not diminish in size by these means, or is a source of much inconvenience to the patient, it must be removed. 2d. Tuberculous sarcocele or scrofulous testicle. —This disease, although occa- sionally met with in individuals otherwise strong and healthy, chiefly occurs in those of a feeble or cachetic constitution, usually in early manhood, and is very commonly associated with a tendency to phthisis. It is essentially characterized by the deposition of tuberculous matter in the testis. These tubercles may be infiltrated or encysted, varying in size from a pin's head to a cherry or plum- stone. When encysted, they are of a bright-yellow color, tolerably firm and SARCOCELE. 969 laminated, contrasting strongly with the inflamed gland, in the midst of which they are deposited. Their presence between the tubuli gives rise to inflamma- tion, and eventual disorganization of the structure of the testis with which they become mixed up, so as to form a pultaceous cream or cheesy mass of a dirty i buff color. The symptoms of scrofulous testis are well marked. The patient perceives that without any very evident cause, or perhaps as the result of an injury, gonorrheal inflammation, or venereal excesses, the testes gradually and slowly enlarge, often attaining a very considerable bulk, and usually becoming at the same time nodulated and irregular, hard and craggy; the hardness being con- fined to the nodules, the gland feeling soft between them, and hydrocele occa- sionally co-existing. The epididymis is most commonly the part that is first affected in this way, though not unusually it is the body of the organ that suffers. Though the disease commences in one testis, both almost invariably eventually suffer, either simultaneously or successively. One of the nodulated masses in the affected testis usually gradually increases in size, the skin cover- ing it becomes red, shining, and thinned, and at last, adhesion forms between it and the testis, indolent suppuration takes place, and on the discharge of the abscess a fistulous open- Fig. 411. ing is left. Through this aperature a fungus spee- dily protrudes, which grows sometimes slowly, at others rapidly, perhaps attaining a very consider- able size (fig. 411). As the fungus increases, the organ atrophies. This fungus is not a new growth, but is a granular mass composed essentially of the tubuli testis and lymph. It is in the form of a pale reddish-yellow granular mass, and is composed of an exuberant outgrowth of the tubuli testis, in- flamed and mixed with lymph and tuberculous mat- ter. If the fungus continues small and firm, it may become a very chronic complaint; but, if large, ra- pidly-growing, and loose-textured, it speedily des- troys the testis. It is, however, surprising how long the functions of this organ will continue, though its tissue is in a great measure destroyed, and its structure traversed by suppurating fistulae. Occa- sionally, however, strumous disease of the testis developes in a different manner the organ enlarging, generally feeling hard and semi-elastic, but uniform and smooth; in fact, like ordinary sarcocele. In examining such a testis, the stru- mous matter, mixed with debris of tubuli, may be found filling up the tunica vaginalis, into which it has protruded, or with which the true envelopes of the testis are incorporated. , The treatment of strumous testis, beibre the fungus has protruded, must be conducted on the general principles laid down when speaking of scrofula : alter- atives, tonics, especially the iodide of iron, with cod-liver oil, and general hygie- nic means calculated to improve the health, must be steadily persevered in for some length of time. The best local treatment will consist in the application of leeches from time to time, followed by discutient iodine lotions, or the iodide of lead ointment. . „ , When the fundus has protruded through one of the fistulous apertures, means must be taken to°repress or remove this, lest it go on to complete destruction of the testis. If it be of small size, the better plan will be to sprinkle it with the red oxide of mercury, and to strap it tightly down with a piece of lint and strapping If larger, it may be shaved off, and the cut surface then dressed with the red oxide of mercury ointment, care being taken, during cicatrization, to repress the granulations below the level of the surrounding integument by strappino- and pressure. Mr. Syme has recommended that the pressure should 970 DISEASES OF THE TESTIS AND CORD. be effected by the integument of the part; an elliptic incision being made round the fungus, the edges of this depressed down, and then brought over the fungus, and retained there by stitches. This operation I have practised with success. 3d. Syphilitic sarcocele, both in its simple and strumous character, has already been considered (page 452), to which I would refer the reader. 4th. Cystic disease of the testis, or cystic sarcocele, may be of two kinds, simple and malignant; when simple, it is a disease somewhat analogous to the cystic sarcoma of the breast. The testis becomes much enlarged, indurated, of a yellowish-white and opaque appearance, and studded Fig. 412. with a multitude of cysts that vary in size, from a pin's head to a cherry, containing clear, amber-colored, or brownish fluid (fig. 412). This affection, consisting in the alteration and condensation of the orchitic structure, with the formation of these distinct inde- pendent cysts, must not be confounded with the acci- dental occurrence of a cyst or two in a scrofulous testis. It is a local affection, and although the organ may attain a considerable bulk, it never gives any in- dication of malignancy. This affection has been carefully studied by Sir A. Cooper, who, with great justice, adverts to the diffi- culty of distinguishing it from other diseases of this organ, more especially from hydrocele. The points to be especially attended to in distinguishing the cys- tic sarcocele, are its want of translucency, the more globular shape of the organ, its weight, and the en- larged and varicose state of the veins of the cord. If there is any doubt, an exploratory puncture will resolve this, and should always be practised. According to Mr. Curling cystic disease of the testicle is the result of mor- bid changes in the ducts of the rete testis, when of an innocent character the cystic disease is characterized by the presence of tesselated epithelium in the cysts, when malignant, by the presence of nucleated cancer cells. In addition to this enchondroma may be met with in both forms of cystic disease, and al- most invariably in old cases of the innocent variety. Cystic sarcocele requires removal of the diseased organ. Occasionally cystic tumors of the testicle are met with, in which the substance of the organ is atrophied or absorbed, and its place occupied by one or more large thin-walled sacculi containing fluids of different color and consistence, dark or fatty. One of the most remarkable of these anomalous tumors of the testis that I have seen was under the care of my colleague, Mr. Marshall, at the hospital. The diseased organ, which was about the size of an ostrich's egg, and felt partly solid and partly fluid, was found after removal to be com- posed of a large cyst filled with an oily fluid, like melted butter, which solidi- fied on cooling. After removal, Mr. Marshall found that the sac contained some foetal debris, and was doubtless of an embryonic character. The patient, who was about thirty years of age, had been affected with the tumor from early infancy. 5th. Malignant sarcocele, or cancer of the testicle, not unfrequently occurs, and almost invariably assumes the encephaloid character. It is, indeed, a ques- tion whether any other form of cancer ever occurs in the testicle. Dr. Walshe a°rees with most observers in doubting the existence of the other varieties of malignant disease in this organ. Cancer of the testicle most commonly occurs in the first instance in the body of that organ, rarely affecting the epididymis primarily. The ordinary charac- CASTRATION. 971 ters of encephaloid, are always well marked in this affection, which eventually assumes a softened-down, pulpy, and fungous character. Intermixed with the encephaloid are commonly found masses of a bright yellow color, which have sometimes been regarded as tuberculous, but, I believe, erroneously so; for in those instances in which I have had an opportunity of examining them I have found them to consist, as in the simple sarcocele, of plastic matter that was un- dergoing fatty degeneration. A malignant testicle may rapidly attain a very considerable magnitude, becoming as large as a cocoa-nut in a few weeks or months. When of this size it is, of course, abundantly supplied by blood-ves- sels; consequently the spermatic artery and accompanying veins will be found a good deal dilated. The lymphatic glands in the neighborhood speedily be- come enlarged, those in the iliac fossa especially, as may be ascertained by deep pressure in the flank. The inguinal glands do not in general become affected until the skin has become implicated by the progress of the disease. It is then also that the cancerous cachexy rapidly develops itself. The symptoms of ^encephaloid testicle are usually somewhat obscure in the early stages, although they become clearly and distinctly developed as the disease progresses. The patient first begins to complain of some degree of dragging pain and weight in one of the testes, which on examination will be found to be indurated and enlarged, though preserving its normal shape. The enlargement continues until the testicle attains about the size and shape of a duck's egg, being somewhat tense and elastic, but smooth and heavy. As it increases in size, which it usually does with rapidity, it becomes rounded and somewhat doughy or pulpy in feel in parts, where, indeed, it may almost be semi-fluctuating, though in others it continues hard and knobbed. This alte- ration in feel is (partly due to softening of the substance of the tumor, and partly to its making its way through the tunica albuginea. The scrotum is much distended, reddened, and purplish, and becomes covered by a net-work of tortuous veins; the cord may be felt somewhat enlarged, hard, and knotty. As the disease advances, the scrotum becomes adherent at some of the softened parts, ulceration takes place, and a fungus projects, which presents all the characteristic signs of fungus haematodes; it does not commonly happen, how- ever, that the disease is allowed to go so far as this before removal. The pain is not very severe at first, but after a time assumes a lancinating character, ex- tending up the cord and into the loins. The only treatment of any avail in encephaloid testicle, is the removal of the diseased organ. This operation is not performed so much with the view of curing the patient of his disease, which will probably return in the iliac glands, or in some internal organ, but as a means of temporary relief from the suffer- ing and incumbrance of the enlarged testicle. It is therefore an operation of expediency, and should only be done in those cases in which the disease is limited to the testicle, the cord being free and the lumbar glands not involved; so that if recurrence takes place it may not be a very speedy one. OPERATION OF CASTRATION. This operation may be required for the various non-malignant affections of the testicle that have resisted ordinary constitutional and local treatment, and have become sources of great annoyance and discomfort to the patient; in the earlv forms of malignant disease it may also be advantageously practised. The operation may be performed in the following way The patient, having had the pubes shaved, should lie upon his back with the legs and thighs hanging over the end of the table. The surgeon should then take his stand in front of the patient between his legs, and grasping the tumor at its posterior part with his left hand make the scrotum in front of it tense. If the mass to be re- moved be of small size he makes a longitudinal incision over its anterior sur- 972 DISEASES OF THE TESTIS AND CORD. Fig. 413. face; if of large size, a double elliptical incision, enclosing a portion of the scrotum. The incision should commence opposite to the external abdominal ring, and be carried rapidly down to the lower part of the scrotum. By a few touches with a broad-bladed scalpel or bistoury, whilst the skin is kept upon the stretch, the tumor is now separated from its scrotal attachments and merely left connected by the cord, which must then be divided. In some cases it will be found advantageous to expose and divide the cord in the first instance before dissecting out the tumor from the scrotum, as in this way a better command over it is obtained. The division of the cord constitutes the most important part of the operation, whether this be done first or last; as unless care be taken it may be retracted through the abdominal ring into the inguinal canal, where it is extremely difficult to follow it, and where the cut stump may pour out a large and even fatal quantity of blood, infil- trating the cellular tissue, and be- tween the muscles of the part and into the flank. This accident is pre- vented by giving an assistant charge of the cord before its division, and directing him to hold it tightly be- tween his finger and thumb (fig. 413), or, what is better, by passing a sharp hook through it, and thus fixing it. After the removal of the testicle, two or three arteries in the cord will generally require ligature, as well as a few bleeding branches in the scrotum. Sutures are not required, the edges coming into ap- position of themselves; the wound must then be lightly dressed, and allowed to heal by granulation; bag- ing in the lower part being prevented during the after-treatment. In cancer of the testicle it is of great consequence to divide the cord as high up as possible for obvious reasons. It will not, however, be safe to do this oppo- site the abdominal ring in the way that has just been described, as there would not be sufficient space for the assistant to hold the cord above the part to be divided. In such cases as these I have found it a good practice to expose the cord by dissection up to the abdominal ring; then to draw it well down and to include the whole in a strong whipcord ligature, tied round it as tightly as pos- sible. The section is then made a quarter of an inch below this, and the ope- ration completed as usual; the cut stump of the cord may retract into the ingui- nal canal, but cannot bleed if properly tied, and would always be under command by drawing upon the whipcord. This plan of tying the cord, en masse, was at one time generally adopted in all cases of castration, but is not now commonly employed. The objection to it' is, that by compressing the spermatic nerves with the ligature the after-pain is increased; but this certainly does not always happen, for in three instances in which I have done it at the hospital, but little pain was complained of; and the practice in malignant disease of the testicle has the advantage of enabling the surgeon to divide the cord at a higher point than he otherwise could; which advantage is still further increased by the parts within and below the ligature sloughing away, and thus eventually carrying the section to a level with the point tied. GENERAL DIAGNOSIS OF SCROTAL TUMORS. 973 GENERAL DIAGNOSIS OF SCROTAL TUMORS. Fig. 414. The diagnosis of scrotal tumors is not only of considerable importance, but is often attended with very great difficulty. The more so as they are frequently associated with one another, so that much tact and care are required to discri- minate their true nature; thus it is not uncom- mon to find a hydrocele and a hernia,—a hydro- cele and a varicocele, — or, these affections co- existing with a solid tumor of the testicle. In other cases again, as in the annexed figure (414), an encephaloid tumor may co-exist with a hydro- cele of the tunica vaginalis, and with an encysted hydrocele of the cord. Tumors of the scrotum may, in a diagnostic point of view, be divided into two distinct classes:—the reducible and the irreducible. The reducible tumors are hernia, congenital hydro- cele, diffuse hydrocele of the cord, and varico- cele ; in all of which the swelling can be made to disappear more or less completely by pressure, and by the patient lying down; reappearing on the removal of the pressure, or on his assuming the erect posture. The mode in which the tu- mor disappears tends greatly to establish its diagnosis; though the general char- acter of the swelling, and the history of the case, afford important collateral evidence on this point. In hernia there are the ordinary signs of this affection, such as impulse on coughing, &c. On reducing the tumor it will be found that its return into the abdomen is accompanied by a gurgling noise, and by the sudden slip upwards of evidently a solid body. In the other reducible tumors, the diminution and eventual disappearance under pressure are more gradual, and there is no reduc- tion of the mass as a whole. The gradual squeezing out of the contents of a congenital hydrocele, together with its translucency, and the early age at which it occurs, will establish its true In the diffuse hydrocele of the cord, there is a uniform semi-fluctuating swell- ing in and near the ring; in which, however, there is no gurgling, &c, no com- plete and sudden disappearance as in hernia. It is also less defined, and has a less distinct impulse on coughing. j-fa^ntt^ Varicocele may always be distinguished by its pyramidal shape, and its knotted soft, and irregular feel. After being reduced when the patient lies down it will when he stands up, fill again, even though the surgeon compress the exter- nal ring with his fingers. This sign, which distinguishes it from a hernia occurs also ^hydrocele, from which, however, the varicocele may be distinguished by the absence of translucency, the want of fluctuation, and the general feel of the ^reducible scrotal tumors are of various kinds such as omental hernia hydro cele hematocele, the various forms of sarcocele, and cancer of the testicle. TW tumor. thou-h presenting certain characters in common, yet differ some- wha tin thrPredomi„aPnce of particular signs; thus the shape of the tumor is usually pyriform in hydrocele, globular in hematocele, and oval in sarcocele titoth this is subject to much variation. The weight is least in hydrocele and though this is soj fcionately to the siZe of the tumor. The characters ^iuS^e^tUnde^le«itono«ilboi»ig smooth and tense in hydro- 974 DISEASES OF THE FEMALE GENITAL ORGANS. cele and hematocele; often irregular, hard or knotted in the other varieties. The rapidity of the formation of the tumor is greatest in hematocele. An irreducible scrotal hernia may be recognized by its irregular feel, its im- pulse on coughing, its occupation of the canal, and by the testicle being dis- tinctly perceptible below it. A hydrocele of the tunica vaginalis is always cognizable by its translucency; and the amount of opacity conjoined with this will enable the surgeon to dis- tinguish the degree of enlargement of the testis, and how far there is a sarcocele conjoined with it. In hematocele the tumor is of sudden or speedy formation, somewhat globular, opaque, but not very heavy or hard, and smooth upon the surface. In sarcocele generally the tumor is heavy for its. size, frequently globular or irregular in shape, sometimes knobbed, and usually attended by a good deal of dragging pain in the groin, and frequently by some enlargement of the cord. The point of most importance in the diagnosis of sarcocele is to distinguish the malignant from the non-malignant varieties. In the malignant, the rapidity of the growth, the softness and the elasticity of the tumor, the implication of one testis only, and the early enlargement of the cord with its indurated and knobbed condition are important signs, especially if the disease occur in young men. In a more advanced condition, the softening of the swelling at parts, with a tuberous condition of the rest, and the occurrence of fungus, with speedy constitutional cachexy, will point to the malignant nature of the tumor. In cases of much doubt and difficulty an exploratory puncture may be made, when the contents of the groove in the needle or the fine canula will probably deter- mine the character of the growth. In more than one instance, in which there was much obscurity attending the diagnosis, I have seen the true nature of the disease cleared up in this way. CHAPTER LXI. DISEASES OF THE FEMALE GENITAL ORGANS. Some of the more important surgical affections of these organs, such as vagino-vesical and recto-vaginal fistulae, lacerated perineum, and the various forms of syphilitic disease to which they are liable, have already been discussed; the remaining affections, implicating the vagina, the uterus, and the ovaries, are of considerable practical interest, but as their full consideration would lead me far beyond the limits that can be assigned to them in this work, I must content myself with a brief indication of the principal points deserving attention. INTRODUCTION OF THE SPECULUM VAGINA. Vaginal specula of various shapes and materials are commonly used by sur- geons. When the os and cervix of the uterus require exploration, the most convenient instrument is certainly the cylindrical reflecting glass speculum (fig. 415), which, being coated with a layer of tinfoil, covered by India rubber, always presents internally a mirror-like surface, by which a strong body of light is thrown into the bottom of the tube. It has the additional advantage of being very cleanly, and not stained by any caustics that may be used in it. These INTRODUCTION OF THE FEMALE CATHETER. 975 Fig. 416. Fig. 416. Bpecula should be of different sizes, and may be sometimes advantageously bevelled off at the inner end. When the wall of the vagina requires examina- tion, as in some operations of fistula, a bivalve speculum (fig. 416), or a cylindrical one, pro- vided with a sliding side, may advantageously be used. These are generally made of some plated metal, or of pewter. The introduction of the specu- lum may readily be effected with- out any exposure of the person, under the dress or bed-clothes. There are two positions in which the patient may conveniently be placed for this purpose. In the first, she lies upon her back, with the nates well raised or brought to the edge of the bed or couch, her legs separated, and her feet resting on two chairs; the surgeon standing or sitting in front of the patient, introduces the fore and middle fingers of his left hand into the vagina, dilates its walls, and passes the speculum well greased, gently and steadily between and under them. This position is the most convenient, when caustics require to be applied, but is often objectionable to the patient, as it appears to entail much exposure, though in reality it need not do so. Another mode of intro- ducing the speculum, and that which should always be adopted when practicable, consists in placing the patient on her left side across the bed, with the knees drawn up, and the nates near the edge; the instrument is then introduced in the same way as before, the surgeon sitting by the patient's side. In whichever way the speculum is used, no force should ever be employed; the patient should be placed opposite a good light, and care should be taken that it be introduced fairly to the uterus, the position of which may have been previously ascertained by tactile examination. INTRODUCTION OF THE FEMALE CATHETER. The use of the female catheter is often required in various diseases and operative procedures about the genito-urinary organs of women It should be introduced without exposure by the aid of the touch alone. This may readily be done, as the patient lies in bed, under the clothes The surgeon standing on her left side, passes his left index finger downwards between the nymph* until he fee s the projection of the meatus urinarius, immediately above the entrance into the vagina; keeping his finger just below this, he uses it as a guide to direct the point of the catheter into the canal. DISEASES OF THE EXTERNAL ORGANS AND VAGINA. The vulva and the nymphse are the seats of numerous morbid conditions, nrincipaUy consisting of hypertrophy or of verrucous growths from them, or the formation of cysts in their substance. 976 DISEASES OF THE i'EMALE GENITAL ORGANS. Hypertrophy of the labia to a limited extent is not unfrequently met with, one labium hanging down considerably below the other. In these cases it will often be found that the enlargement is due to a kind of solid oedema, originally dependent perhaps upon a fissure or ulcer of the part. In other cases again, large fibro-cellular tumors form as outgrowths from the natural structures in this region; these may require removal by simple excision. Large condylomata or verruce are often met with here, as the result of gonorrheal or syphilitic disease, forming at last irregular pendulous masses, which require extirpation, either by knife or scissors. I have had occasion also to remove a large nevus by ligature from this situation, and in fact almost any growth that occurs in the fibro-cellular tissue may be met with here. Cystic tumors are not unfrequently met with in the labia, and may sometimes resemble pretty closely the ordinary forms of inguinal hernia, for which, how- ever, their incompressibility, irreducibility, and the absence of impulse on coughing will prevent their being confounded. These cysts which require removal by a little simple dissection, usually contain a dark, turbid, or san- guineous fluid, and sometimes atheromatous matter. Tolerably free hemorrhage may follow their removal, the excitable tissues of the labia being cut into. This may however always be arrested by pressure and a "f bandage. Occasionally they project from the inside of the vagina, and then require removal by dissec- tion or ligature, as can be best practised. An imperforate vagina is occasionally met with in young children, and occa- sions a good deal of anxiety to the parents. This condition, however, may always be very readily and speedily removed by tearing up the canal as it were, by dragging upon its walls in opposite directions and breaking through the adhesions, which are little more than epithelial, with the thumb nail, a blunt probe, or the handle of a scalpel, and then introducing a small pledget of greased lint. An imperforate hymen has occasionally been met with, causing great incon- venience by the retention of the menstrual secretion, which may accumulate to an immense extent, and become converted into a kind of chocolate-colored gru- mous fluid; in these cases, incision of the membrane is the only remedy. Occa- sionally the surgeon's advice may be sought by married women, for a rigid and only partially perforate hymen, when incision with a probe-pointed bistoury, and dilatation with a sponge tent may be required. Absence of the uterus and ovaries with imperforate vagina is occasionally met with in women, otherwise perfectly well developed. In such cases as these the true condition may be detected by an examination per rectum, and especially by the introduction of a catheter into the bladder whilst the finger is in the rectum, when the point of the instrument will be felt thinly covered through the gut. In a case of this kind in which I was lately consulted, there had been monthly epistaxis. No surgical interference can be of any avail in such cases, and an attempt to restore the vagina might lead to the opening of the peritoneal cavity. Hypertrophy of the clitoris is occasionally met with; this organ becoming en- larged, elongated, and pendulous, and in some cases attaining an enormous size. When enlarged, it may give rise to a good deal of irritation, and require excision, an operation that would probably be followed by rather troublesome hemorrhage. Removal of the clitoris, even though not much enlarged, has of late years been recommended as a means of cure in some forms of erotomania. I per- formed the operation for this purpose on a patient of Dr. Horsbrugh's, and found some difficulty in stopping the bleeding, which at last required the application of the actual cautery before it could be arrested. The operation was I believe followed by marked improvement in the young lady's mental condition. Tumors of various kinds are met with in the interior of the vagina, springing UTERINE DISCHARGES, DISPLACEMENTS, ETC. 977 from its walls. These may be of a cystic character, but occasionally true mu- cous polypi are found dependent and projecting from the side of this canal. These may most readily be removed by transfixing their base by a double whip- cord ligature, and then strangling it. In performing this operation, however, when the tumor grows from the posterior wall, care must be taken to ascertain by proper digital examination, that a portion of the rectum has not been dragged down into its base. Prolapsus of the anterior or the posterior wall of the vagina may occur, giving rise in the first instance to protrusion of the bladder or cystocele, in the next, to a rectocele; in either case, but especially in the first, occasioning very serious and troublesome consequences, amongst which, chronic irritation of the mucous membrane of the bladder, with perhaps phosphatic deposits in the urine, are the most marked. These protrusions may be supported by the use of pro- perly constructed belts or pessaries. In some cases the surgeon may feel dis- posed to undertake plastic operations, having for their object the narrowing of the vao-inal orifice by freely paring the opposite portions of its walls, bringing too-ether the freshened surfaces by means of the quilled suture, and thus pro- curing narrowing of the canal and permanent support to the protruded part. The success of such operative proceedings will greatly depend on attention to detail. The mucous membrane at the orifice of the vagina should be dissected off from about half an inch below the meatus on one side, to a corresponding part on the other, in a strip about three-quarters to an inch wide; the dissec- tion being carried well up posteriorly in the fourchette. Two or three deep, and as many superficial sutures should be passed; the deep being left in for about five, the superficial for seven days. Great attention should be paid to cleanliness, the patient lying on her side with a catheter in the bladder commu- nicating with an india-rubber tube to carry off the urine, and the bowels con- fined by opium. Various discharges connected with the female organs of generation fall under the observation of the surgeon; these may bccur from the external organs, from the mucous membrane covering the cervix uteri, or from the interior of the cavity of that organ. These discharges, when proceeding from the mucous membrane covering the external organs or lining the vagina, are frequently, thouo-h not necessarily, of a gonorrheal character; and then require to be treated in the way that has been mentioned at page 876. When of a simple nature, proceeding from mere hypersecretion of these parts, astringent injections, and attention to the general health will usually succeed in effecting a cure. _ When these discharges proceed from the cervix or the interior of the os uteri, they will commonly be found to be dependent upon a chronica ly inflamed or congested condition of the organ, or upon a papillated, granular, fissured or ulcerated condition of the mucous membrane, often connected with more or less local thickening and induration of subjacent structures These various con- ditions often of a very persistent, insidious, and destructive character, have of kte vears been fully recognized by the labors of some of the French surgeons, mt^rt^ ^B1^ TdY BeT natholoev has been greatly elucidated by Simpson and Bennett lo JJr. Ren- netespecial is due the great credit of having pointed out the true pathology of vSs uterine diseases that were previously but imperfectly recognized, and of S shown that many of the so-called functional diseases of the uterus are k[rJLity decent on congestion, inflammation, and other structural lesions of this organ. „„„11T.r;no- nsnallv as the result of chronic inflam- These uterine discharge ;; occurring«suayaB &g ^ 7^ "to ^T^^^de* by various symptoms indicative of the urethra, throat, or eye ^ more iall 1Q 1'S1 X$*%Z£*& -d ™n'a g00d deal of 8jmpatheti0 con- 62 978 DISEASES OF THE FEMALE GENITAL ORGANS. stitutional irritation, terminating in impaired digestion, malnutrition, and ane- mia. It is in this condition of the system that many of the so-called hysterical affections are so apt to arise; and the surgeon will often find that the most inve- terate case of neuralgia of the joints, the spine, the hip, or the breasts — amau- rotic, and other obscure affections connected with nervous irritation — are primarily dependent on chronic uterine disease, and it is only by attacking and removing this that he will remedy the secondary mischief. On examining the condition of the cervix and os uteri in these cases, by means of the speculum, various morbid changes will be observed in them; the cervix is perhaps thick- ened, indurated, or knobbed on one side, the os is frequently patulous, and the mucous membrane covering these parts will be observed to be erythematous, congested, and perhaps excoriated; not unfrequently in a granular condition, closely resembling what may be observed in some forms of granular conjuncti- vitis. In other cases, again, true ulceration may exist both upon the cervix and within the os. These ulcers, abrasions, excoriations, or by whatever term they may be designated, are unquestionably a fruitful source of mischief in this situation, giving rise to considerable thickening of subjacent structures, usually to abundant muco-purulent discharge and much sympathetic irritation. Their characters closely resemble corresponding forms of disease met with on the mucous surface in other situations, not attended by loss of .substance, but by the development of small pointed granulations or papillae, from which the dis- charge is poured forth. The treatment of these various affections of the uterus has been materially simplified since their pathology has been better understood, and practitioners are now generally agreed as to the necessity of the employment of energetic local measures for the removal of these morbid states. To the surgeon wbo is in the habit of managing local disease on other mucous surfaces, and of remov- ing the structural lesions that result from chronic inflammation in other organs, the treatment of these cases can present little difficulty, as it is conducted on precisely the same principles that guide him in the management of similar affections elsewhere. The employment of caustics is of essential service in these various forms of chronic uterine disease. In cases of simple ulceration or excoriation, the nitrate of silver in stick applied every third or fourth day will frequently be found to effect a speedy cure. For this purpose, the hinge caustic-holder will be found a useful instrument (fig. 417). If there be much chronic induration Fig. 417. conjoined with the affection of the mucous membrane, the potassa cum calce, fused into narrow sticks, may very advantageously be used. In doing this, however, care must of course be taken that the caute- rizing action do not extend too far. Hence the surgeon, after lightly touching the diseased part, whether this be on the cervix or inside the os, should immediately inject some weak vinegar and water, so as to neutralize the alkali. After these applications, which should only be repeated at lengthened intervals, the patient must be kept quiet for some time, and any inflammatory symptoms that may be excited, combated in the usual way; it very rarely happens, however, that anything untoward will result. After the removal of the local disease in the way pointed out, any remaining congestion may be got rid of by the application of leeches to the cervix. During the time that these local measures are being adopted, proper constitutional treatment must be had recourse to, with the view of improving the general health on ordinary medical principles, which need not be detailed here, but for a full exposition of which, as well as for a vast deal of important information on the surgical management of uterine affections, I would refer the reader to the last edition of Dr. H. Bennet's work on the Uterus. UTERINE DISPLACEMENTS, TUMORS, AND POLYPI. 979 The various displacements to which the uterus is liable, whether downwards, constituting prolapsus, or in the direction of the axis, being twisted, and either retroverted or anteverted, are causes of much local suffering and con- stitutional disturbance, and commonly require surgical treatment. These various conditions will frequently be found dependent on inflammatory congestion of the fundus, in consequence of which the organ becomes as it were top-heavy, and is tilted to one side, or descends bodily in the pelvis. The treatment, under such circumstances, must have reference to the removal of the local turges- cence by the application of leeches, the employment of astringents, hip-baths, and the recumbent position; occasionally assisted, perhaps, in twist of the organ, by attempts at replacing it by introducing the uterine sound into its cavity, or, when it is prolapsed, by supporting it with appropriate pessaries and the abdominal bandage. Tumors of the uterus are of various kinds. The most common are those of a fibrous character; these are often of considerable size, and have been found weighing many pounds; they may occupy almost any portion of the uterus, either projecting into the peritoneal cavity, occupying the interior of the organ, or dependent into the vagina. These tumors seldom occur before the age of thirty or forty, and are not very amenable to treatment. In some cases, how- ever, considerable benefit results from attention to position, the occasional appli- cation of leeches to the cervix, so as to lessen the congestion of the organ, and the introduction into the vagina every night of a ball composed of equal parts of strong mercurial ointment, wax, and lard, or one containing iodine, or the iodide of lead, with the view of acting as an absorbent on the morbid tissue. Polypi are not unfrequently met with growing from the inner surface of the uterus, usually from the posterior aspect or fundus. These growths are gene- rally oval or pyriform, smooth, hard, and insensible, and the cause of repeated hemorrhage; and it is a remarkable fact, that in many cases the most violent bleedino- proceeds from the smallest tumors. In other cases, the tumors of the uterus are of a soft fibro-cellular, vesicular, or mucous character, attended, like the harder ones, by free hemorrhage. The treatment of polypi of the uterus is best conducted by ligaturing their pedicle. This may usually be readily enough effected by means of a whip-cord lio-ature applied by Gooch's double canula, which has been variously modified and a good deal improved by different surgeons. The ligature should be gra- dually tightened, and usually cuts its way through in from three to five days; the tumor swelling, decomposing often with a good deal of fetid discharge, which requires to be carefully syringed away by means of dilute chlorinated lotions It is a useful precaution not to apply the ligature too near the uterine end of the pedicle, as cases have occurred in which, by so doing, the surgeon has given rise to serious and even fatal inflammation of the womb. Any portion of pedicle that is left will gradually undergo absorption < The cauliflower excrescence from the uterus attended by copious discharge, is a rare and dangerous affection. The only treatment that appears to be of any avail is to draw down the neck of the uterus by means of a vukellum, and then to excise the tumor with the surface from which it grows. This operation is not attended by any very serious hemorrhage, and succeeds in ridding the natipnt effectually of her disease. . Malianant affections of the uterus usually commence in the form of scirrhous tuberelfor ulceration of the cervix, attended by the ordinary local and consti- tational symptoms of this affection; there is much offensive discharge, and cancerous cachexy speedily sets in. palliative character- the ThP treatment of these cases must be of a purely palliative character, tne administration of opiates and the use of chlorinated lotions must be principally Id on Excision of the diseased cervix has been recommended, and was 980 DISEASES OF THE FEMALE GENITAL ORGANS. formerly a good deal practised; but this is a barbarous procedure, and one contrary to every principle of good surgery, as it is impossible to rid the patient of scirrhous disease by the partial removal of the affected organ, and its com- plete extirpation cannot be thought of. Tumors, however, of a simple character requiring removal are occasionally met with springing from the cervix; they must be excised by putting the patient in the position for lithotomy, drawing the uterus well down with forceps and removing them with the knife; this has been done during pregnancy, and even during parturition, with good effects. OVARIAN TUMORS AND DROPSY. Ovarian tumors of a cystic character are commonly met with. The cysts may be uni- or multi-locular, and vary greatly in the nature of their contents. These may be either solid or fluid, — often a combination of the two. If fluid, the liquid is usually more or less viscid, albuminous, dark, and variously colored. Ovarian tumor invariably tends to progress to a fatal termination; in some cases, rapidly, in most, gradually, occupying many years in its course. The treatment of ovarian tumor may be conducted :—1st, by medical means; 2d, by tapping; 3d, by tapping, conjoined with auxiliary measures; 4th, by injection; 5th, by extirpation. 1st. Medical means exercise no influence in curing, and but little, if any, in retarding the progress of ovarian tumors. Specific treatment by means of mercury or iodine, has always appeared to me to hasten the progress of the malady by breaking down the constitutional powers of the patient; and attempts at promoting the absorption of the fluid by purgatives, diuretics, &c, are invariably unsuccessful. An ovarian cyst is a rasitic growth, the tissues of which are not influenced to increased power of absorption by the action of deobstruents on the system generally. The utmost that can be done by medical means in such cases, is, to attend to the general health and to support the tumor by a belt. 2d. Tapping in ovarian dropsy, may be done as for ascites, through the linea alba; but not unfrequently the tumor presents more distinctly at some other part of the abdominal wall, and may be emptied through the linea semi-lunaris, or, if multilocular, may require the trochar to be inserted at different points into its separate compartments. The paracentesis of ovarian cysts should, unless the disease be very acute, always be deferred as long as is compatible with the comfort of the patient, as it is not only followed by speedy re-accumu- lation of the fluid, and often by rapid exhaustion, few patients surviving the first operation more than three or four years; but is attended by certain special dangers, such as the risk of induction of peritonitis, or possibly even the puncture of the bladder, or of a coil of small intestine, which is sometimes adherent to the anterior wall of the ovarian cyst, and may be met with where little expected. 3d. Tapping, conjoined with other means, has occasionally succeeded in effecting a cure of the disease. These auxiliary means are of various kinds:— firm pressure; incision of the cyst; excision of a portion of its wall, plugging the aperture in it with a tent; the introduction of a catheter or tube; the establishment of a fistulous opening leading into the interior of the cyst, either through the anterior abdominal wall or through the vagina, have all been adopted in addition to simple tapping; and however much these different procedures may vary in detail, they are all conducted on one principle, viz., that of causing the gradual contraction of the cyst and the cohesion of its walls, a principle of treatment which is only applicable to unilocular cysts, and OVARIAN TUMORS AND DROPSY. 981 hence can only be had recourse to in a small number of, and those the simplest cases of ovarian tumor. 4th. The injection of tincture of iodine has, of late, been successfully em- ployed both in this country and on the continent. After the tumor has been tapped, from four to six ounces of the tincture should be injected through a catheter passed down the canula and left in. In some cases no constitutional disturbance follows; in others, a severe febrile paroxysm; and in others again, peritonitis has resulted. This method of treatment has been very successful in many cases, and is well deserving a more extended trial than it has as yet received. It is only applicable, however, to non-adherent unilocular cysts. 5th. Ovariotomy. Ovarian cysts and tumors may require removal, either on account of their large size and the consequent inconvenience occasioned by it, or from their rapid growth exhausting the patient, and threatening a speedy extinction of life. These operations have of late years been frequently performed with success, and their introduction into surgical practice has been mainly due to the labors of Drs. F. Bird and Clay. Much discrepancy of opinion has existed amongst practitioners as to the propriety of performing these operations, which have been chiefly condemned on the grounds that as the disease for which they were performed, was not necessarily fatal, or at all events not incompatible with long life, it was not proper to subject the patient to a hazard- ous procedure for its removal; and that the mortality from the operation was so high as not to justify a surgeon in performing it. With regard to the first objection, it may be stated that ovarian disease is attended by very great discomfort and inconvenience in all cases; and that it is not generally compatible with prolonged existence so soon as it attains such a size as to require tapping. Mr. Stafford Lee states that of 46 patients with ovarian disease, who were tapped, 37 died, and only 9 recovered; and that of the 37 who died, more than one-half did so in four months from the first tapping, and 27 out of the 37 within a twelvemonth, and of these 18 were only tapped once. In those who survive, repeated tappings are required, the interval between each decreasing as they are repeated. The second objection can have little weight with any practical surgeon. The mortality after ovariotomy is not so high as that after many operations, which no surgeon would hesitate for a moment in performing. Dr. Lyman, of New York, in a valuable essay on this operation, has collected from various sources the particulars of 300 cases; and of these the operation was completed by the removal of the tumor in 208> or about two-thirds of the cases. /In one case the result is not stated; but of the 299 cases in which it is, 120 died, or at the rate of 40 per cent.}; of the 208 cases in which the operation was completed, 89 died, or nearly 43 per cent. Out of the whole 300 cases, therefore in 119, or 39 J per cent., was the operation successful in the removal of the disease and the recovery of the patient. Of the 88 cases in which the operation was abandoned, in 68 instances this arose from adhesions ; in 8 cases no tumor was found; and in the remainder the tumor was not ovarian. Of the whole of the cases in which the operation was unfinished, 27 died. # . . The mortalitv after ovariotomy is increased by the existence ot adhesions. When these complicated the operation, 47 per cent, of the cases died; when they did not exist, 32 per cent, were fatal. The mortality is greater in early life; smaller between the ages of 50 and 60 When we compare these returns with the rate of mortality after primary amputation of the thigh, amputation at the hip, that following the ligature of the innominate or subclavian arteries, or indeed even in strangulated hernia in hospital practice, we cannot consider it as of a magnitude to interfere with the performance of the operation if other circumstances justify it. 982 DISEASES OF THE FEMALE GENITAL ORGANS. It has further been objected to ovariotomy, that it has not unfrequently happened that after the operation has been commenced, it has been found impossible to complete it, owing to the existence of adhesions between the tumor and the contents of the abdomen. This objection is certainly a grave one; but 1 believe that with care in examining the tumor, ascertaining its mobility during respiration, the existence or not of crackling under the abdo- minal wall during the respiratory movements, the absence of connection with the uterus, as determined by finding that organ floating on the introduction of the uterine sound, and the previous non-occurrence of peritonitis, this mis- take is not now so likely to happen as formerly, when the liability to it was not suspected. It is not my intention to enter into the difficult subject of the diagnosis of ovarian tumors. From pregnancy, ascites, tumors of the uterus and omentum, enlargements of the liver, kidney, spleen and stomach, hydatids, hysterical tympanitis, fat in the omentum, stercoraceous accumulations, distension of the bladder, spinal curvature, abdominal and pelvic abscesses, the diagnosis has carefully to be made, and that this is a matter of no slight difficulty is evident from the numerous cases in which errors have happened and are constantly occurring to most experienced practitioners. It is impossible for the surgeon to be too cautious in effecting a diagnosis before he proceeds to open the abdo- minal cavity in any supposed cases of ovarian disease. There is, however, one form of disease that so closely resembles an ovarian cyst, that I may refer to it; it is a dilated state of the fallopian tube, containing fluid,— in fact, dropsy of that tube. This condition may generally be recognized by the tumor being of moderate size, wholly fluid, having deep pelvic adhesions, displacing the uterus and bladder, and drawing up the vagina into a pouch. The displacement is often very remarkable and considerable. I have seen the bladder flattened out and drawn up as high as the umbilicus—the top of the vagina above the pubes. In these cases the abdominal wall is not so much thinned and expanded as in true ovarian disease. The tumor, which cannot of course be extirpated, is never pediculated. Operation. — On the day preceding the operation a dose of castor-oil should be administered, and on the morning of it an enema, so that the bowels may be completely emptied. The room having been raised to a temperature of at least 75° or 80° F., chloroform administered, and the bladder emptied by the cathe- ter, the patient must be placed upon a table covered with blankets, in such a way that the legs hang over the end of it, and the abdomen is fairly and evenly exposed. The surgeon, taking his stand between the patient's legs, makes an incision, about four inches in length, from the umbilicus downwards, directly in the mesial line; by a few touches of the knife, the structures, which are usually much thinned, are divided along the linea alba, and the abdominal cavity opened. There has been much discussion as to the length to which the incision in the abdominal wall should be made, some practitioners recommending that this should be of very limited extent, others that it should reach from the ensiform cartilage to the pubes. No definite rule can be laid down upon this point. The incision must be proportioned in extent to the size and nature of the tumor, and the existence or not of adhesions. If the tumor be cystic, and not adhe- rent, it may be readily enough extracted by making an incision an inch or two in length, in the mid-line, tapping it through this, and then drawing the emp- tied cyst forwards by means of a vulsellum. If, on the other hand, the ovarian growth be chiefly solid, a larger incision, from four to six inches in extent, will be required. Should adhesions exist, it may even be necessary to go beyond this, though I cannot believe that it is ever necessary to rip up the abdomen OVARIAN TUMORS AND DROPSY. 983 from the sternum to the pubes, for the removal of any tumor, however large or adherent. If it be found that the adhesions are so extensive and firm that the tumor cannot be removed, it must be tapped, and the wound in the abdominal wall closed. The tumor now comes into view: if cystic, it must be tapped with a large trochar and the fluid evacuated. Should this be very thick and viscid, the aperture in the sac may be enlarged with a probe-pointed bistoury, and thus its contents let out. In this way the size of the tumor may be so much lessened as to admit of its more ready extraction. If cystic and emptied, it may now perhaps be drawn out through the incision in the abdominal wall without further difficulty. If solid, or if there be any adhesions, the surgeon must introduce his hand, and thus assist in removing the mass, or gently break down any connections it may have formed with adjacent parts. These will chiefly be found at the anterior part, between it and the abdominal wall; seldom or ever posteriorly, or to any of the abdominal viscera, except the uterus. During the withdrawal of the mass from the abdomen, an assistant on either side must press upon the sides of the incision with their hands or with soft napkins, so as to prevent the protrusion of the intestines. This some- times occasions considerable trouble, especially if the patient have taken chloro- form and begin to vomit, when it may be necessary to discontinue the operation for a time. The separation of the pedicle is the next step, and perhaps the most important one in the operation. This may best be done by drawing the tumor well forwards, transfixing the pedicle with a nevus-needle carrying a strong whip-cord ligature, tying it firmly on either side, and then cutting it across above the constricted portion. In doing all this, a few points require attention. Care should be taken that the needle does not transfix any large artery or vein. This may generally be avoided by spreading out or unravelling, as it were, the pedicle and examining its structure before passing the ligature. After it has been transfixed, and before the cord is tied, it is well to dissect off that portion of the peritoneal investment of the pedicle which corresponds to the line that will be constricted by the ligature. In doing this great care must, however, be taken not to wound the vessels, especially the veins, which are very thin-walled. In this way there will, I think, be less risk of peritonitis, as there is less chance of any slough of the pedicle falling into the peritoneum; and I attribute much of the success that attended the removal of an ovarian tumor, partly solid and partly cystic, weigh- ing about fifteen pounds, which I extracted from a lady, sixty-five years of age, to the adoption of this precaution. After the ligature of the pedicle, it should be divided about half an inch above the part tied. If it be cut across nearer the ligatures than this, there will be danger of the stump retracting under them, and thus inducing secondary hemorrhage, which has proved fatal in no less than 23 per cent, of the deaths after this operation. _ The next point in connection with the pedicle is fixing it properly out of the peritoneal cavity, so that it may not be drawn back into this, as it always has a tendency to do, and thus excite undue inflammation by the presence of the li-atures and resulting slough in the serous membrane. I have found the most convenient way to fix it is to close the lower part of the incision in the abdomi- nal wall by a hare-lip pin passed across it, about half an inch above its angle, and drawin- the stump of the pedicle well out of the abdomen through this, to retain it there by twisting the whip-cord ligature with which it has been tied, in the usual figure of 8 manner, round the pin; in this way it cannot possiby be retracted, and there is no chance of any of the slough or ligature falling into the peritoneal cavity. 984 DISEASES OF THE FEMALE GENITAL ORGANS. The incision in the abdomen must be closed by a series of interrupted sutures passed across from one lip to the other, and the abdominal wall must be still further supported by broad and long shps of plaster, and a laced napkin round the body. The after-treatment of the case will require the most careful attention. The patient should be kept in bed, in a high and uniform temperature. Nothing but ice- and barley- or Seltzer-water should be allowed for several days, and opium must be given in sufficient and repeated doses, to keep the system slightly influenced by it. The urine must be drawn off thrice in the twenty-four hours, but the bowels should be left unrelieved for at least ten or twelve days, and then merely opened by an enema. As no solid food should be given during the whole of this time, little inconvenience results. If peritonitis comes on, it must be treated in accordance with the rules laid down when speaking of strangulated hernia. INDEX. Abdomen, contusions of, 325 injuries of, 325 tapping the, 849 wounds of, 326 Abdominal injuries, treatment of, 327 Abscess, 341 diagnosis of, 344 in groin, diagnosis of, 642 iliac, 643 ischio-rectal, 831 knife, 346 psoas, 642 treatment of, 345 urinary, 894 varieties of, 342 Acetabulum, fracture of, 222 Acromion, fracture of, 212 Adenitis, 465 Adhesion, primary, 112 Air in veins, 143 causes of, 145 treatment of, 146 Air-passages, foreign bodies in, 312 Ala nasi, restoration of, 695 Amputating instruments, 37 Amputations, 36 at ankle, 57 of arms, 57 breast, 764 in burns, 339 Chopart's, 55 in contused and lacerated wounds, constitutional gangrene, 359 for disease, 44 of fingers, 47 foot, 54 forearm, 51 in frostbite, 340 of great toe, 54 in gunshot wounds, 128 of hand, 49 how influenced, 43 Hey's, 55 at hip, 63 for injury, 44 in joint diseases, 636 at knee, 61 of leg, 60 of little toe, 55 metacarpus, 50 metatarsal bones, 54 mortality after, 42 Amputations — continued. in necrosis, 592 Pirogoff's, 58 in popliteal aneurism, 527 primary, 45 results of, 44, 45, 46 secondary, 45 in fractures, 203 hemorrhage after, 173 in senile gangrene, 360 of shoulder, 52 special, 49 statistics of, 44, 45, 46 subastragaloid, 58 Syme's, 57 synchronous, 40 through tarsus, 55 of thigh, 61 thumb, 49 toes, 54 varieties of, 37 Vermale's, 61 of wrist, 50 Anaesthetics, 29 local, 33 Anchylosis, 618 treatment of, 619 Anemia, 141 Aneurism, 482 accidents alter operation for, 501 amputation in, 528 by anastomosis, 564 arterio-venous, 167 of axillary artery, 552 bone, 604 brachial artery, 562 carotid, 537 cause of, 494 circumscribed traumatic, 166 dissecting, 484 diagnosis of, 492 duration of, 487 femoral, 520 of forearm, 562 fusiform, 482 gangrene in, 506 of iliac arteries, 515 inguinal, 514 ligature in, 497 medical treatment of, 495 mode of death in, 491 recurrent pulsation in, 501 (9 85> 986 INDEX. Aneurism — continued. popliteal, 520, 526 pressure-effects of, 486 sacculated, 483 secondary, 501, 503 structure of, 486 spontaneous cure of, 490 of stumps, 41 subclavian, 546 suppuration and sloughing of, 504 surgical treatment of, 497 symptoms of, 488 terminations of, 490 of tibial arteries, 629 traumatic, 166 treatment of, 495 by compression, 507 galvano-puncture, 513 injection, 514 manipulation, 512 Valsalva's treatment in, 496 varicose, 169 varieties of, 482 Aneurismal varix, 168 Aneurisms of innominata, 529 distal ligature in, 532 Angeioleucitis, 464 Ankle, amputation at, 57 dislocation of, 268 excision of, 634 fractures near and through, 233 Antiphlogistics, 86 Antrum, diseases of, 709 suppuration of, 709 tumors of, 710 Anus, artificial, 789 operation for, 820 cancer of, 829 fissure of, 829 fistula of, 832 imperforate, 823 malformation of, 823 prolapse of, 845 spasmodic contraction of, 831 ulcer of, 829 Aorta, ligature of. 519 wounds of, 325 Aphonia, 724 Arachnitis, erysipelatous, 381 Arm, amputations of, 51 contractions of, 677 Arteries, arctation of, 474 atheroma of, 476 bruised, 149 calcification of, 477 changes in, after ligature, 161 degenerations of, 476 diseases of, 473 dissection of, 159 t femoral, wounds of, 182 of forearm, wounds of, 181 hand, wounds of, 181 injuries of, 148 of leg and foot, traumatic aneurisms of, 182 leg and foot, wounds of, 183 ligature of, 156 Arteries — continued. mode of exposing, 158 mode of ligaturing, 168 occlusion of, 474, 480 spontaneous ligature of, 480 structural disease of, 476 torsion of, 156 torn, 149 ulceration of, 480 wounded, treatment of, 164 wounds of, 149 Arterio-venous wounds, 168 Arteritis, 473 Artery, axillary, ligature of, 561 traumatic aneurisms of, 177 wounds of, 177 brachial, ligature of, 563 traumatic aneurisms of, 180 wounds of, 180 carotid, wounds of, 176 distal ligature of, 533, 543 ligature of, 540 traumatic aneurisms of, 177 common iliac, ligature of, 518 external iliac, ligature of, 517 femoral, ligature of, 523 iliac, ligature of, 515 innominata, ligature of, 547 internal iliac, ligature of, 520 subclavian, ligature of, 549, 552 distal ligature of, 532 wounds of, 177 tibial, ligature of, 529 Arthritis, 610 chronic rheumatic, 659 traumatic, 238 Atheroma, 476 Artificial respiration, 310 Asphyxia, 308 from irrespirable gases, 311 secondary, 311 Astragalus, compound dislocation of, 271 dislocation of, 269 excision of, 633 Atheromatous tumors, 389 Axilla, removal of tumors from, 764 Balanitis, 951 Bandage, plaster of Paris, in fractures, 197 starch, in fractures, 194 Bed sores, 360 Bladder, catarrh of, 851 diseases of, 850 extroversion of, 857 puncture of, in cases of stricture, 892 fasciculated, 852 inflammation of, 850 irritability of, in gonorrhea, 871 irritable, 851 in women, 853 paralysis of, 854 puncture of, 864 rupture of, 333 sacculated, 852 stone in, 899 tumors of, 853 Blepharoplasty, 700 INDEX. 987 Blood, changes of, in inflammation, 70 extravasation of, within skull, 292 transfusions of, 142 Blood-vessels, injuries of, 140 Boils, 365 Bone, abscess of, 581 aneurism's of, 604 bending of, 185 cancer of, 601 cystic tumors of, 598 diseases of, 579 fractures of, 185 hydatids in, 600 hypertrophy of, 593 injuries of, 184 mode of sawing, 38 pulsating tumors of, 604 rebreaking of, 581 softening of, 594 structural changes of, 598 suppuration of, 580 tubercle of, 596 tumors of, 590 Brain, extravasations on, 292 foreign bodies in, 290 inflammation of, 275 injuries of, 272 treatment of, 277 irritation of, 275 wounds of, 289 Breast, abscess of, 748 amputation of, 764 cancer of, 753 treatment of, 758 chronic mammary tumor of, 749 cystic sarcoma of, 752 tumors of, 750 diagnosis of tumors of, 757 diseases of, 743 encysted abscess of, 748 hypertrophy of, 745 inflammation of, 746 neuralgia of, 744 tumors of, 749 Bridles, 102 Bronchocele, 742 Bubo, 438 Buffer accidents, 325 Bullet extractors, 127 BuDion, 663 Burns, 335 amputation in, 339 treatment of, 338 Bursae, diseases of, 663 Calcaneum, excision of, 632 fractures of, 234 Calculus (see Stone) Callus, 190 ossification of, 191 Cancer, 399 of bone, 601 causes* of, 405 caustics in, 407 cells, 401 chimney-sweeper s, 953 compression in, 409 Cancer — continued. congelation of, 410 diagnosis of, 406 epithelial, 414 operation for, 415 treatment of, 415 excision of, 410 operations for, 411 of skin, 462 removal of, by ecraseur, 415 by ligature, 416 treatment of, 406 Counter-irritants, 85 Cancrum oris, 364 Carbuncle, 365 Caries, 582 operations for, 583 syphilitic, 451 Carpus, dislocation of, 258 Cartilage, disease of, 611 Cartilages, loose, in joints, 638 Castration, 971 Catheter, caustic, 871 female, introduction of, 975 prostatic, 862 Catheters, 882 Caustics in cancer, 407 in epithelial cancer, 416 Cauteries in hemorrhage, 155 Cautery, 85 Cellulitis, 372 Cephalcematoma, 281 Cerebral disturbance, 273 Chancres, 427 diagnosis of, 430 treatment of, 436 of urethra, 430 varieties of, 428 Cheeks, diseases of, 687 injuries of, 301 Cheiloplastic, 694 Cheloid, 394 Chest, hemorrhage into, 322 injuries of, 318 tapping the, 765 Cholesteatoma, 395 Chloroform, 29 administration of, 29 caution in using, 30 dangers of, 31 death from, 32 mortality after, 29 overdose of, 32 in shock, 32 treatment of overdose of, 32 Cicatrices, 102 changes in, 101 faulty, 116 indurated syphilitic, 437 structure of, 102 Cicatrization, 102 Circulation, collateral, 162 Circumcision, 949 Clavicle, dislocation of, 247 excision of, 625 fractures of, 210 Cleft palate, 715 988 EX. Clitoris, hypertrophy of, 976 Cloacae, 588 Club-foot, 669 Coagulum in wounded arteries, 151 Cold as an anaesthetic, 33 effects of, 340 in hemorrhage, 155 Collateral circulation, 162 Collodion, 115 Colloid, 400-404 Columna nasi, restoration of, 694 Coma, 274 diagnosis of, 293 Compress, graduated, 156 Compression in aneurisms, 507 of brain, 274 Concussion, 273 effects of, 274 Condylomata, 448 Congestion, 66 treatment of, 67 Conservative surgery, 629 Contractions, 665 causes of, 666 Contre-coup, 283-290 Contusions, amputation in, 119 degrees of, 109 diagnosis of, 109 treatment of, 110 varieties of, 109 what constitutes, 109 Coracoid process, fracture of, 213 Corns, 456 Coronoid process, fractures of, 217 Counter-opening, 347 Coxalgia (see Hip-disease) Cranium, necrosis of, 592 Croup, spasmodic, 731 Cuboid, excision of, 634 Cut throat, 305 Cystine, 902 Cystitis, 850 Cystocele, 977 Cysts, 389 compound, 392 multilocular, 392 sanguineous, 393 Deformities, 667 Delirium, inflammatory, 108 irritative, 108 traumatic, 108 treatment of, 108 Determination of blood, 68 Diathesis, hemorrhagic, 569 Diet after operations, 35 before operations, 28 Disarticulations, 36 Dislocations, 239 of ankle, 268 astragalus, 269 carpus, 254 clavicle, 247 compound, 244 congenital, 265 of elbow, 253 finger, 259 Dislocations — continued. foot, 268 with fracture, 244 of hip, 260 jaw, 246 knee, 266 metacarpus, 258 metatarsus, 271 patella, 265 reduction of, 242 of scapula, 272 shoulder, 249 Bpine, 300 spontaneous, 245 of tarsus, 271 thumb, 259 treatment of, 241 of vertebrae, 301 wrist, 257 Dissection wounds, 138 Dressing of wounds, 34 Drowning, 308 Dura mater, 679 Ear, diseases of, 681 Ears, bleeding from, 284 foreign bodies in, 302 injuries of, 302 serous discharge from, 284 Ecraseur, 415 Ectropium, operation for, 701 Elbow, dislocation of, 253 excision of, 625 fractures near, 216 Emphysema, 319 of abdominal wall, 327 Empyema, 320 Encephalitis, traumatic, 275 Encephalocele, 679 Encephaloid, 400-404 Enchondroma, 398 Enterotome, 791 Entropium, operation for, 701 Epicanthis, operation for, 701 Epididymitis, 955 Epispadias, 948 Epistaxis, 683 Epithelioma, 414 Epulis, 708 Erysipelas, 366 causes of, 368 cellular, 373 cellulo-cutaneous, 370 contagion of, 369 cutaneous, 370 external, 369 of fauces, 379 fingers, 377 head, 877 infants, 376 internal, 379 of larynx, 380 phlegmonous, 370 of pudenda, 377 scrotum, 377 serous membrane, 381 treatment of, 374 INDEX. 989 Ether, administration of, 33 Excision of ankle, 633 of astragalus, 633 calcaneum, 632 clavicle, 625 cuboid, 634 elbow, 625 foot, 630 great toe, 632 in gunshot wounds, 128 of hip joint, 656 joints, 620 knee, 635 hand, 628 lower jaw, 713 radius, 628 scapula, 625 shoulder joint, 623 ulna, 628 upper jaw, 712 wrist, 627 Exostosis, 598 Extravasation of blood in abdomen, 329 of fasces, 329 Eyeball, cancer of, 681 Extirpation of, 681 injuries of, 303 Eyelids, operation on, 700 tumors of, 680 Eyes, gonorrheal inflammation of, 875 wounds of, 303 Face, injuries of, 301 plastic surgery of, 692 False passages, 885 Fatty tumors, 394 Feet, deformities of, 669 Femur, fractures of, 322 Fever, hectic, 95 hemorrhage, 141 after operations, 27 surgical, 27 Fibrine, 90 Fingers, amputation of, 47 dislocation of, 260 enchondroma of, 399 erysipelas of, 377 fractures of, 221 Fistula, 348 aerial, 308 in air passages, 308 ano, 833 operation for, 833 entero-vaginal, 848 in perineo, 894 lachrymalis, 680 rectal, 848 recto-vaginal, 849 vesical, 848 salivary, 302 urethro-vaginal, 897 urinary, 895 vesico-vaginal, 897 Flaps, 38 Foot, amputations of, 54 conservative surgery of, 631 disarticulation of, 57 Foot — continued. dislocations of, 268 fractures of, 234 Forceps, artery, 158 cutting, 591 Forearm, amputations of, 51 fractures of, 217 Foreign bodies in bladder, 333 in brain, 290 rectum, 334 vagina, 334 Fractures, 185 accidents in treatment of, 197 of acetabulum, 222 acromion, 212 amputations in, 203 near ankle, 233 badly set, treatment of, 204 of base of skull, 282 calcaneum, 234 causes of, 185 disunion in, 205 of clavicle, 210 complicated with dislocation, 199 complications of, 199 compound, 200 compound, 199 of leg, 232 treatment of, 201 of coracoid process, 213 costal cartilages, 235 coronoid processes, 217 displacement in, 189 near elbow, 216 of femur, 222 treatment of, 228 fingers, 221 foot, 234 forearm, 217 great tubercle of humerus, 215 humerus, 213 hyoid bone, 210 leg, 232 lower end of humerus, 216 lower end of radius, 217 lower extremity, 221 lower jaw, 209 malar bones, 209 maxillary bones, 209 metacarpus, 221 nasal bones, 208 neck of femur, 222 humerus, 213 olecranon, 217 pelvis, 221 patella, 230 re-setting of, 204 of ribs, 235 sacrum, 222 scapula, 212 near shoulder, 212 signs of, 188 simple treatment of, 192 of skull, 282 spine, 299 treated by starch bandage, 194 ununited, 204 L 990 INDEX. Fractures — continued. ununited, treatment of, 206 union of, 190 varieties of, 188 of vertebrae, 298 zygoma, 209 Frost-bite, 340 Fungus, cerebri, 290 of dura mater, 679 Galvanic cautery, 348 Ganglion, 664 Gangrens, 352 from arrest of circulation, 354 arteritis, 474 in fractures, 197 inflammatory, 103 treatment of, 104 line of demarcation in, 104 separation in, 104 after ligature, 174 causes of, 175 treatment of, 176 after operation for aneurism, 506 from occlusion of arteries, 481 senile, 355 amputation in, 360 treatment of, 357 spontaneous, 355 traumatic, 117 amputation in, 120 varieties of, 353 Gastrotomy, 819 Genu-valgum, 672 Glands, lymphatic, diseases of, 465 Glossitis, 702 Gonorrhea, 866 complications of, 870 sequences of, 871 treatment of, 868 in women, 875 Gouge forceps, 591 Granulations, 100 vascularization of, 100 Gums, diseases of, 708 Gunshot injuries, period of amputation in 129 wounds, 121 amputations in, 128 apertures of, 123 excisions in, 129 immediate attention to, 125 peculiarities of, 122 symptoms of, 125 treatment of, 125 Hematoma, 393 Hand, amputations of, 47 conservative surgery of, 629 deformities of, 678 Hanging, treatment of, 312 Hare-lip, 688 treatment of, 689 Head, diseases of, 679 injuries of, 272 Heart, rupture of, 324 wounds of 323 Hectic, 95 Hematocele of cord, 964 spontaneous, 963 traumatic, 963 Hematuria, 854 Hemorrhage, 141, 149 arrest of, 150 in gunshot wounds, 126 arterial, 141 constitutional effects of, 172 after operations, 27 permanent arrest of, 152 secondary, 171 secondary, treatment of, 173 from stumps, treatment of, 173 surgical treatment of, 154 venous, 140 Hemorrhagic fever, 141 Hemothorax, 319 Hernia, 766 accident in operation for, 788 adhesions in, 787 causes of, 769 cerebri, 290 congenital, 802 director, 782 diaphragmatic, 812 femoral, 804 diagnosis of, 806 operation for, 807 infantile, 803 inflamed, 773 inguinal, 796 diagnosis of, 799 operation for, 801 irreducible, 772 obturator, 811 knife, 783 omentum in, 787 operation without opening sac, 792 perineal, 811 pudendal, 812 radical cure of, 771 reduction in mass, 794 state of intestine in, 785 sciatic, 812 strangulated, 774 diagnosis of, 777 operation in, 781 stricture in, 775 structure of, 767 taxis in, 778 umbilical, 809 treatment of, 770 vaginal, 812 ventral, 810 Herniary peritonitis, 784 Hip, amputation at, 63 statistics, 66 disease, 650 treatment of, 655 varieties of, 652 dislocations of, 260 joint, excision of, 657 rheumatic arthritis of, 650 Horns, 390 Hospital gangrene, 361 INDEX, 991 " Housemaid's " knee, 662 Humerus, fractures of, 213 lower end, fracture of, 216 Hydatids in bone, 600 Hydrarthrosis, 608 Hydrocele, 957 congenital, 958 of cord, 963 coverings of, 958 diffused, of cord, 963 encysted, 962 radical cure of, 960 spermatozoa in, 963 tapping, 959 Hydrophobia, 134 Hydrosarcocele, 968 Hymen, imperforate, 976 Hyoid bone, fracture of, 210 Hypospadias, 948 Ice as an anaesthetic, 33 Impotence, 872 Incisions, 34 Increased vascular action, 67 Inflammation, 68 active, treatment of, 78 adhesive, 89 asthenic, 87 bloodletting in, 80 causes of, 77 changes of blood in, 70 chronic, treatment of, 83 coagulation of blood in, 71 cold in, 79, 82 curative treatment, 79 duration of. 77 effects of, 76 effusive, 88 extension of, 77 fomentations in, 83 gangrenous, 103 gangrenous, arrest of, 104 causes of, 103 treatment of, 104 guides to bloodletting, 80 heat in, 82 local bleeding in, 81 signs of, 72 low treatment of, 87 mercurials in, 80 metastasis, 76 phenomena of, 69 preventive treatment of, 7$ punctures in, 81 secondary, forms of, 88 state of vessels in, 69 stimulants in, 85 suppurative, 92 symptoms of, 71 termination of, 76 ulcerative, 97 Inflammatory effusions, 88 fever, 74 Injury, effects of, 106 Insects, stings of, 132 Instruments, amputating, 37 Intestines, obstructions of, 813 Intestine — continued. state of, in hernia, 786 wounded, treatment of, 329 wounds of, 327 in hernia, 788 Iritis, syphilitic, 451 Irrigation, mode of applying, 79 Issues, 85 Jaw, dislocations of, 246 fractures of, 209 lower, diseases of, 713 excision of, 713 necrosis of, 593 subluxation of, 247 upper, excision of, 712 diseases of, 709 Joints, diseased, amputation in, 637 diseases of, 607 excision of, 620 in gunshot wounds, 128 false, 204 treatment of, 206 hysterical, 666 inflamed, incisions into, 616 treatment of, 615 inflammation of, 610 injuries of, 236 loose cartilages in, 638 neuralgia of, 639 stiff, 618 strumous, disease of, 617 traumatic arthritis, 238 wounds of, 237 Knee, amputation at, 61 anchylosis of, 673 compound dislocations of, 267 contractions of, 672 deformities of, 673 dislocations of, 266 excision of, 635 stiff, forcible extension of, 674 subluxation of, 267 Knot, clove hitch, 242 reef, 158 Labia, cystic tumors of, 976 hypertrophy of, 976 Lachrymal gland, extirpation of, 68] sac, puncture of, 680 Laryngitis, 722 oedematous, 724 Laryngotomy, 734 advantages of, 738 Larynx, chronic irritation of, 724 diseases of, 722 erysipelas of, 380 nervous affection of, 731 tumors in, 732 topical medication of, 725 ulceration of, 730 Leg, amputation of, 59 fracture of, 232 Leucorrhea, 977 Ligature, 156 accidents after, 171 992 Ligature — continued. in aneurisms, 497 application of, 157 immediate effects of, in arteries, 1 introduction of, 156 kinds of, 157 mode of tying, 158 in nevus, 567 Ligatures, 39 Limbs, artificial, 40 Lip, cancer of, 691 Lipoma, 395, 684 Lips, diseases of, 687 fissures of, 687 hypertrophy of, 687 tumors of, 687 Lithectasy, 946 Lithotome cache", 931 Lithotomy, 910 dangers in, 924 bilateral, 930 causes of death after, 924 in children, 920 difficulties of, 920 hemorrhage in, 923 lateral, 911 instruments, 911 and lithotrity compared, 941 Marian, 929 median, 928 median and lateral compared, 929 supra-pubic, 927 in women, 947 Lithotrity, 933 accidents of, 939 cases requiring it, 934 instruments, 935 stages of, 937 in women, 947 Liver, rupture of, 326 Lung, hernia of, 322 wounds of, 318 Lupus, 459 exedens, 460 non-exedens, 459 structure of, 460 Lymph, 89 development of, 89 Lymphatic glands, diseases of, 465 Lymphatics, diseases of, 464 Lymphatitis, 464 Mad animals, bites of, 134 Mollities ossium, 594 Melanosis, 400-405 Mercury in syphilis, 431, 442 Metacarpus, amputation of, 50 dislocation of, 258 Metatarsal bones, amputation of, 54 Metatarsus, dislocation of, 271 "Miner's" elbow, 662 Mortification, 352 Mummification, 352 Mumps, 740 Muscles, diseases of, 665 injuries of, 183 ruptures of, 183 INDEX. Nails, diseases of, 457 ingrowing, 458 removal of, 458 Necrosis, 585 of special bones, 592 in stumps, 40 syphilitic, 451 Neck, hydrocele of, 742 tumors of, 741 Needles, extraction of, 131 Nerves, inflammation of, 570 injuries of, 140 Nevus, 565 treatment of, 566 Necrosis forceps, 591 Neuralgia, 571 of joints, 639 Neuroma, 573 Nipple, cracked, 746 diseases of, 746 Nodes, 450 Nose, cancer of, 684, 686 diseases of, 683 gonorrheal inflammation of, 874 polypi of, 684 restoration of, 695 Nostrils, foreign bodies in, 302 plugging of, 683 Obstruction, intestinal, 813 (Edema, inflammatory, 377 ffisophagotomy, 318 (Esophagus, diseases of, 720 injuries of, 319 structure of, 720 Olecranon, fracture of, 216 Omentum, state of, in hernia, 787 Onychia, 457 malignant, 458 syphilitic, 447 Operation, Amussat's, 820 Anel's, 498 for aneurisms, 497 blepharoplastic, 700 for cancer of breast, 761 caries, 584 of castration, 972 causes of death after, 27 cheiloplastic, 699 of excision, 620 hemorrhage after, 27 for hernia, 781 Hunterian, 498 for impermeable stricture, 890 on lower jaw, 713 for necrosis, 690 permeable stricture, 887 Petit's, 792 preparations for, 29 rhinoplastic, 694 on tongue, 705 of resection, 620 results of, 25 in scrofula, 424 shock after, 27 on tumors, 416 Tagliacotian, 695 INDEX. 993 Operation — continued. treatment of, after, 35 on upper jaw, 712 vaginal fistulae, 897 for varicose veins, 471 Wardrop's, 499, 532 on windpipe, 731 Wutzer's, 771 Operations, 25 Ophthalmia, gonorrheal, 873 Orbit, injuries of, 303 Orchitis, 955 Osteitis, 579 Osteo-aneurisms, 604 cancer, 601 Osteomalacia, 594 Osteo-myelitis, 580 Osteo-pyelitis, 580 Osteotrite, 584 Otitis, 681 Ovaries, dropsy of, 980 treatment of, 980 Overlaying, 311 Oxygen, use of, in asphyxia, 311 Palate, fissures of, 715 Palmar arches, wounds of, 181 Parotid, diseases of, 740 duct, division of, 302 tumors of, 740 Patella, dislocations of, 265 fractures of, 231 necrosis of, 593 Pelvic viscera, injuries of, 332 Pelvis, fractures of, 221 injuries of, 325 necrosis of, 592 Penis, amputation of, 952 cancer of, 951 diseases of, 948 herpes of, 951 warts on, 951 Pericardium, tapping the, 765 Perineal section, 890 Perineum, laceration of, 335 Periostitis, 579 syphilitic, 450 Peritonitis, herniary, 784 erysipelatous, 381 traumatic, 332 Phagedena, 361 Pharyngotomy, 318 Pharynx, diseases of, 720 scalds of, 316 Phlebitis, 467 Phymosis, 948 Piles, 835 caustics in, 844 operation for, 843 treatment of, 841 Plasters, 114 Plaster of Paris bandage, in fractures, 191 Plastic surgery, 692 Pneumocele, 322 Pneumonia, traumatic, 320 Polypi, 394 uterine, 979 63 Polypi — continued. nasal, 684 Posthitis, 951 Paraphymosis, 950 operation for, 950 Prepuce, disease of, 948 hypertrophy of, 951 Pressure in hemorrhage, 155 Probang, for larynx, 725 Prolapsus ani, 845 operation for, 847 Prostate, abscess of, 857 cancer of, 865 chronic, inflammation of, 858 diseases of, 857 hypertrophy of, 859 inflammation of, 857 section of, in lithotomy, 915 stone in, 933 tumors of, 859 Ptosis, operation for, 701 Purulent injections, 382 Pus, 92 characters of, 94 diagnosis of, 94 within cranium, 277 Pyemia, 382 causes of, 384 changes of blood in, 384 treatment of, 386 Pyrexia, 74 Rabies, 134 Radius, excision of, 628 fractures of, 218 impacted fracture of, 218 Ranula, 707 Rectocele, 977 Rectum, cancer of, 828 malformation of, 823 stricture of, 825 Resection of bones, 620 in necrosis, 592 Resections (see Excisions) Respiration, artificial, 310 Rheumatism, gonorrheal, 875 Rhinoplasty, 694 Ribs, fractures of, 235 necrosis of, 593 Rickets, 593 Rupture of abdominal organs, 326 of bladder, 332 Sacro-iliac disease, 645 Sacrum, fractures of, 222 Salivary fistula, 302 Sarcocele, 968 cystic, 970 malignant, 970 strumous, 969 syphilitic, 452 Sarcomatous tumors, 394 Saw, Butcher's, 623 for necrosis, 591 Saws, amputating, 38 Scabbing, 111 Scalds, 335 994 Scalds — continued. of pharynx, 316 Scalp, contusions of, 280 excoriations of, 282 extravasations under, 281 injuries of, 280 wounds of, 280 Scapula, excision of, 625 fractures of, 212 lower end of, dislocated, 272 necrosis of, 592 Scars, 101 Scirrhus, 400, 402 Scrofula, 418 causes of, 422 operations in, 425 treatment of, 423 Scrotum, cancer of, 953 diseases of, 953 erysipelas of, 377 hypertrophy of, 953 inflammatory oedema, 953 tumors in, diagnosis of, 973 Serre-fine, 114 Sequestrum, 587 Setons, 85 Shock, 106 chloroform in, 32 after operations, 27 treatment of, 107 Shoulder, amputation of, 52 dislocations of, 249 fractures about, 212 joint, excision of, 622 Sinus, 348 Skin, cancer of, 462 surgical diseases of, 456 syphilitic diseases of, 446 Skin, tumors of, 458 ulcers of, 458 Skull, base of, fracture of, 284 concussion of, 282 depressed fractures of, 286 extravasation within, 292 fractures of, 282 by contre-coup, 283 injuries of, 282 punctured fracture of, 286 simple fracture of, 283 Sloughing phagedaena, 361 Sloughs, separation of, 104 Snake-bites, 132 Sounding for stone, errors in, 909 Sounds, 907 Speculum ani, 829, 845 vaginae, 975 Spermatorrhea, 872 Sphacelus, 352 Spina bifida, 649 ventosa, 599 Spinal cord, divisions of, 297 wounds of, 297 Spine, angular curvature of, 640 caries of, 640 concussion of, 296 diseases of, 640 dislocations of, 300 INDEX. Spine — continued. fractures of, 299 injuries of, 296 lateral curvature of 645 Splints, use of, 194 Sprains, 183, 236 Squint, 667 Staphyloraphy, 716 Starch bandage, in fractures, 194 Sternum, necrosis of, 592 Stomach, rupture of, 326 Stomatitis, 364 Stone in bladder, 899 causes of, 905 encysted, 905 in kidneys, 903 operations for, 910 in prostate, 933 secondary, 945 sounding for, 907 spontaneous rupture of, 904 structure of, 902 symptoms of, 906 in urethra, 932 in women, 946 Strains, 183, 665 Stricture, complications of, 891 of urethra, 876 Stumps, structure of, 40 aneurisms of, 41 conical, 41 degeneration of, 42 dressing of, 39 fatty, 42 malignant, 42 morbid conditions of, 40 necrosis of, 41 neuralgic, 41 secondary hemorrhage from, 173 spasmodic, 41 strumous, 42 Styptics, 155 Suppuration, 92 Surgeon, responsibilities of, 28 Sutures, 34, 113 beaded, 114 continuous, 114 figure of, 34, 114 interrupted, 114 quilled, 114 twisted, 114 in wounded intestine, 331 Symblepharon, operation for, 701 Synovitis, 607 Syphilides, 446 Syphilis, 426 of bones, 450 throat, 449 consecutive, 437 constitutional, 440 of hair, 447 infantile, 453 inoculation of, 427 of iris, 451 larynx, 450 local secondary, 446 mercury in, 435-442 INDEX. 995 Syphilis — continued. of muscles, 453 nose, 450 primary, 426 treatment of, 431 secondary, 440 treatment of, 443 simple treatment of, 432 of skin, 446 testis, 452 tongue, 449 in women, 430 Talipes calcaneo-valgus, 672 calcaneus, 670 equineo varus, 671 equineus, 669 varus, 670 valgus, 672 Tapping the abdomen, 849 chest, 705 pericardium, 765 Tarsus, amputation through, 55 caries of, 584 dislocations of, 271 Taxis, 778 Tendo-achillis, ruptures of, 184 division of, 669 Tendons, ruptures of, 183 Tenotome, 666 Tenotomy, 666 Testis, cancer of, 970 cystic disease of, 970 gonorrheal inflammation of, 872 inflammation of, 955 undescended, 95.7 malposition of, 954 neuralgia of, 954 scrofulous, 969 tumors of, 968 Tetanus, 575 state of nerves in, 577 Thigh, amputation of, 61 fractures of, 222 Throat, injuries of, 305 wounds of, 305 Thumb, amputations of, 49 dislocations of, 259 Thyroid gland, diseases of, 742 Toes, amputations of, 54 excision of, 632 Tongue, abscess of, 703 cancer of, 703 diseases of, 702 inflammation of, 702 ligature of, 705 operations on, 705 prolapse of, 702 psoriasis of, 703 removal of, 706 syphilitic tubercle of, 703 tied, 702 Tonsil-guillotine, 719 diseases of, 718 removal of, 719 Torsion of arteries, 156 Torticollis, 668 Tourniquets, 154 Trachea tubes, 738 forceps, 736 hook, 735 Tracheotome, 736 Tracheotomy, 734 difficulties in, 734 and laryngotomy compared, 738 Transfusion, 142 Trephining of bone, 581 in extravasated blood, 294 in fracture of skull, 288 operation of, 295 for pus within cranium, 277 results of, 296 Trochar for tapping chest, 765 suction, 344 Tubercle, 421 of bone, 596 subcutaneous, 574 Tumors, 387 cartilaginous, 398 encysted, 389 fatty, 394 fibro-cellular, 395 fibro-plastic, 397 fibrous, 396 fibro-vascular, 458 myeloid, 397 non-malignant, 389 operations for removal of, 416 recurring fibroid, 397 sarcomatous, 394 varieties of, 388 Ulcer, healthy, 349 hemorrhagic, 351 indolent, 349 inflamed, 350 irritable, 350 sloughing, 350 varicose, 351 varieties of, 349 weak, 349 Ulcers, 349 Ulceration, 97 treatment of, 102 Uterus, absence of, 976 Ulna, excision of, 628 Union by first intention, 111 by second intention, 113 ^f wounds, 35, 111 Urethra, diseases of, 865 laceration of, 334 stricture of, 876 treatment by caustics, 886 by dilatation, 882 division, 886 vascular tumors of, 899 stone in, 932 Urethritis, 865 Urethroplasty, 896 Urethrotomy, 887 Urine, deposits in, 899 extravasation of, 893 J incontinence of, 856 retention of, 855 996 INDEX. Urine — continued. from enlarged prostate, 862 in stricture, 891 Uterus, cancer of, 979 discharges from, 977 displacements of, 979 polypi of, 979 tumors of, 979 ulceration of, 978 Uvula, elongated, 717 excision of, 719 Vagina, diseases of, 975 imperforate, 976 prolapsus of, 977 walls of, 977 Varicocele, 965 operations for, 967 treatment of, 967 Varix, 469 aneurismal, 168 ligature of, 472 Veins, air in, cases of, 145 canalization of, 145 diseases of, 407 entry of air into, 143 treatment of air in, 146 varicose, 469 wounds of, 142 Vertebrae, dislocations of, 360 fractures of, 299 Vulsellum scissors, 718 Warts, 393, 456 venereal, 440, 448 Wens, 394 White swelling, 617 Whitlow, 377 Wind contusions, 124 Wounds, 110 arterio-venous, 168 of arteries, treatment of, 164 contused, 116 amputation in, 119 treatment of, 118 dissection, 138 dressing of, 34 gunshot, 178 incised, 110 treatment of, 113 lacerated, 116 poisoned, 132 punctured, 131 union of, 35, 111 of veins, 142 Windpipe, operations in, 732 Wrist, amputation of, 50 dislocations of, 257 excision of, 027 fractures near the, 218 Wry-neck, 668 Xanthine, 903 THE END. i?jr5'~ , :«•» ■•d********* NATIONAL LIBRARY OF MEDICINE NLM Q320bflb3 b -Vfxsr: NLM032068636