Three Years’ Experience with the Electrical Treatment of Fibroid Tumors of the .Uterus WITH A REPORT OP FORTY-POUR CASES W. L. BURRAGE, A.M.. M.D., Electrotherapeiittstr Free Hospital for Women; Surgeon to Diseases of Women, St. Elizabeth’s Hospital; Gynecol- ogist to Out-Patients, Carney Hospital; Clinicallnstructor in Gynecology, Har- vard University, Boston, Mass. REPRINTED FROM The American Journal of Obstetrics Vol XXIX. No 3,1804. NEWYORK WILLIAM WOOD & COMPANY. PUBLISHERS 1894 THREE YEARS’ EXPERIENCE WITH THE ELECTRICAL TREATMENT OP FIBROID TUMORS OP THE UTERUS.1 WITH A REPORT OP FORTY-FOUR CASES. May 9th, 1891, I had the honor to read before this Society a paper on the technique of the Apostoli method of treatment, and announced at that time my purpose later of reporting results. In a paper published in the Boston Medical and Sur- gical Journal for June 16th, 1892, I gave some results in the treatment of pelvic inflammation. I wish now to give results in the treatment of fibroids. My interest in this subject was especially aroused by a visit to Apostoli at his clinic in Paris in the summer of 1889. Al- though I treated several cases of fibroids with electricity during the following year, it was not until the establishment of the electrical clinic at the Free Hospital for Women in this city, in October, 1890, that the opportunity was afforded me to apply electricity to any considerable number of patients. It is now ten years since Apostoli first called the attention of the profession to the electrical treatment of fibroids. The sub- ject is still under judgment, and it is my purpose in presenting this paper to add my mite toward the determination of the place that electricity should hold in the treatment of this very com- mon disease with which women are afflicted. I approached my task in an unprejudiced frame of mind, having read, on the one hand, Apostoli’s articles, and also the Keiths’ book, in which they declared their intention to lay aside the knife in favor of electricity; and, on the other, the attacks of Lawson Tait and •other abdominal surgeons on this therapeutic measure. I have tried not to be biassed and to give the treatment a fair trial— to see facts as they are, and not as I should like to have them. 1 Read by invitation before the Obstetrical Society of Boston, January 13th, 1894. 2 BURRAGE .* ELECTRICAL TREATMENT OF The diagnoses are my own, though sometimes I have had the corroboration of such men as Drs. W. H. Baker, F. 11. Daven- port, J. B. Swift, F. W. Johnson, and the late Dr. C. P. Strong, all of whom kindly sent me cases. I want here to express my obligations to them and to the many other practitioners who have referred cases for treatment. The diagnoses have been confirmed by repeated examinations extending over months and often years, and under varying conditions. During the three years from October 18th, 1890, to October 18th, 1893, I have seen in hospital and private practice ninety- eight cases of fibroid tumor of the uterus. Forty-four of these were treated with electricity and received at least six treat- ments each. I present the chief facts as to these forty-four cases in tabular form to-night. The cases treated with less than six applications have been excluded from consideration. Ho men- tion is made, also, of the cases of doubtful diagnosis. A number were treated tentatively, and it has been only in those instances where the diagnosis was reasonably sure after numerous exami- nations that they have been included in the tables. In an ex- perimental way were treated two cases of ovarian cystoma (dia- gnosis confirmed by celiotomy in one); a cyst of the broad ligament (celiotomy); a case of cancer of the uterus (micro- scopic examination of piece removed for diagnosis) ; a fibroid with malignant degeneration; and many cases of pus tubes, several verified by subsequent operation. I satisfied myself in these cases that electricity had no effect except in a majority to relieve pain. In a considerable number of the cases included in the tables I was favored in making a diagnosis by an ether examination, and in a few by an ether examination at the begin- ning and another at the end of treatment. At the Free Hospital electrical clinic there were made during the three years 2,176 applications of electricity. Hot all of these were to fibroids, as the clinic is for the application of electricity in the diseases of women. For the details of treatment you are referred to my paper on the technique before spoken of. It was published in the Bos- ton Medical and Surgical Journal for Hovember 26th, 1891. I have followed Apostoli’s methods rigidly, except in one particu- lar, and that is, I have given vaginal galvanism in certain cases where experience taught favorable symptomatic results were to be expected, and where it was an anatomical impossibility to FIBROID TUMORS OF THE UTERUS. 3 give intra-uterine treatment or impossible or inexpedient to puncture. The treatment was usually begun with vaginal ap- plication. Apostoli, as you know, claims that vaginal galvanism is useless. A word as to instruments used. For battery, Law cells, forty- eight at the hospital and sixty-five at my office ; for faradism, Waite & Bartlett’s three-coil Dubois-Reymond apparatus ope- rated by four Law cells; for galvanometers, the Gaitfe and Mclntosh; for rheostats, the Bailey and Massey ; for clay plate, that manufactured by Waite & Bartlett—clay in muslin, ten by twelve inches; for intra-uterine electrodes, platinum tips, one- inch and two-inch; for vaginal electrodes, a brass ball covered with thick layers of absorbent cotton and gauze; for faradism, the vaginal and intra-uterine bipolar electrodes of Apostoli; for puncture, the gold-tipped Apostoli needle. The measure- ments, both uterine depth and circumference of the abdomen, have all been made with the same steel tape graduated in centimetres. Measurements of the abdomen were in every case taken with the patient lying on the back with knees bent and all clothing loosened. The following measurements were taken: Circumference at umbilicus ; circumference at largest part; distance from tip of ensiform cartilage to the umbilicus, from umbilicus to pubic symphysis, and from umbilicus to the anterior superior spine of the ilium on each side. And here let me say it has been a constant source of regret that exact measurements of the size of fibroid tumors cannot be made. The condition of fulness or emptiness of the intestines, bladder, and rectum, the varying thickness of the fat of the parietal walls and omentum, and the changing shape of the tumor with accompanying alteration in direction and length of the uterine canal, effectually prevent accurate measurements with calipers or otherwise. We have to be governed by tactile sense, and by repeated examinations under as nearly similar conditions as possible, before deciding on the relative size of a given tumor. The fact that fibroids are smaller just after the catamenia and larger during and just before, and also that they vary in size from day to day owing to temporary engorgement or depletion, has been forcibly im- pressed on me since I have followed up this subject. The intra-uterine measurements were taken with the greatest possible precision, careful attempts being made to get the ex- 4 BURRAGE : ELECTRICAL TREATMENT OF treme depth in every instance ; measurements with the steel tape direct from the sound or probe. The treatments have been made twice a week as a rule, and of an average duration of from four to eight minutes. Cleanliness and antisepsis have been the practice. For de- tails I must refer to my former paper already alluded to. It has been my custom to give personal attention to tbe details, and I have myself examined all the cases and kept track of them from the beginning of treatment. My aim has been to follow up the patients for as long a time as possible, in order to gain reliable information as to the per- manency of results. Three years seems to be a reasonable length of time for an investigation of this sort. In the tables the ° mark means milamperes. Unless other- wise specified, the treatments are with galvanism, P is for positive, IS" for negative. F, M, and C are for fine, medium, and coarse coils. The faradism is bipolar vaginal, unless some other form is indicated. In analyzing the results I shall con- sider the cases first from an anatomical standpoint—the increase or decrease in size of the tumor; and, second, from a symptoma- tic point of view—the effect on pain, hemorrhage, and general liealth. Although forty-four cases are included in the tables, we shall consider only thirty-five in our analysis of anatomical results, for the reason that nine of tbe forty-four have either not had suffi- cient intra-uterine application, or have not been under observa- tion what, to me, seems a proper length of time. The nine cases are JS"os. 36 to 44 inclusive. Each of the thirty-five cases has had at least six treatments with galvanism, either intra-uterine or by puncture, and with intensities rising fifty milamperes, and in addition has been under observation at least four months from the beginning of electrical treatment, a majority from one and a half to two years. When possible, and in most instances, I purposely refrained from prescribing tonics or any other treat- ment, local or general, so that the results might be fairly attri- buted to the electricity. In speaking of the symptomatic re- sults I include the entire forty-four cases, except in estimating permanent benefit, where a minimum of four months under observation will be adhered to, thus limiting the number to thirty-five. First, anatomical results—the effect of galvanism on the size FIBROID TUMORS OF THE UTERUS. 5 of fibroids. Of thirty-five cases, nine, Nos. 1, 3, 7, 10, 14, 16, 16, 19, and 27, showed a decrease in size at the end of periods ranging from one to eight months from the beginning of treat- ment. But in six of these nine, Nos. 1, 10, 14, 16, 19. and 27, at the end of periods of time varying from one and a half to twro and a half years the tumor was as large as at the beginning, or larger: Nos. 1, 10, 16, and 19 were larger, Nos. 14 and 27 were the same size. The other three, Nos. 3, 7, and 15, were lost track of in eight months, four months, and eight months respec- tively. That is to say, we have no positive evidence that any of the tumors were permanently lessened in size as a result of electrical treatment—a showing not at all in accordance with the published results of Apostoli and others. Seven out of thirty-five, Nos. 1, 4, 9, 10, 12, 16, and 19, were a little larger at the end of one and a half to two and a half years. Four of these were treated with galvano-puncture : No. 9 by puncture through the abdominal walls with two steel needles by Dr. Baker, a current of one hundred and twenty-five milamperes for ten minutes being used ; the other three were treated by vaginal puncture after the method of Apostoli. The seven cases had treatments in number as follows : No. 1, 50 ; 4, 49 ; 9, 40 ; 10, 18 ; 12, 20 ; 16, 13 ; and 19, 41. No. 4 increased a little in size in eight months and then remained stationary for a year and a half. In No. 10 a myomectomy was done and opportunity of- fered to measure the fibroid nodule exactly. Myomectomy was also done in No. 33 of my series. In No. 16 a hysterectomy was performed, the tumor proving to he rather soft from a pre- dominance of the muscular elements. Deducting from thirty- five the seven cases in which the tumor became larger and the three cases in which it was smaller when the patient was last seen, and we have left twenty-five as the number of cases in which the tumor remained of the same size. It has been my experience that galvanism clears up pelvic inflammatory exudate and improves the physical condition of inflamed tubes and ovaries, unless there is pus present. A fib- roid uterus, fixed and immovable, after treatment with galvan- ism becomes free ; a mass in the pelvis made up of tube, ovary, and exudate disappears. Such a result was noted in seven of my cases, Nos. 1, 5, 8, 23, 27, 29, and 31. The only other change in the physical conditions that seemed to be due to electrical 6 BUEEAGE 1 ELECTEICAL TEEATMENT OF treatment was an increase in the panniculus adiposus of the abdominal j>arietes. The uterine measurements show very little change as a result of treatment, in this respect varying from some of the results reported by other observers. Every effort was made to take the uterine depth always in the same manner. Fractions of a centimetre must be allowed for the tip of the probe going into a horn of the uterus, for its catching on a projection in the canal, and for uneven pressure on the crown of the cervix by the registering finger or forceps. Intra-uterine applications of galvanism, positive, have a tem- porary curative effect on the endometritis of fibroids, but not a permanent effect. An illustrative case is ISTo. 27, who had the most thorough intra-uterine treatment with positive galvanism. The large gas-carbon electrodes and high intensities were used with prolonged applications, the uterine cavity being accessible and carefully gone over from fundus to external os. One year after the electrical treatment I curetted her and obtained abun- dant tissue, which Dr. F. B. Mallory, the pathologist, examined microscopically and said was from hyperplastic endometritis. F7o. 16, the case of hysterectomy, is another instance. When I laid open the tumor at the close of the operation, abundant soft, pink, velvety tissue, easily scraped off a glistening white sur- face, lined the entire uterine cavity; and, by the way, neither the pathologist nor I, after a careful search, could find any evi- dence of a cicatrix in the mucous membrane of the canal. Cervical stenosis following high intensities has occurred in many of my cases. It prevents subsequent treating the interior of the uterus with large electrodes. It has not caused dysmenor- rhea in my experience, and the stricture has never been so tight as to prevent the passage of a probe. In using high intensities it has been my aim to get the tip of the electrode as near the fundus as possible, to obviate the annoyance that might result from a stricture low down. Second, the symptomatic results. It has seemed simplest and best first to classify the thirty-five cases under four headings, as follows: 1,, those that were relieved of pain permanently; 11., those that were relieved of flowing permanently; 111,, those in whom there was improvement of general strength and ability to work; and, IY., those that experienced no permanent benefit. Of I. (those relieved of pain) there were eleven cases, FIBROID TUMORS OF THE UTERUS. 7 Hos. I, 2, 4, 9, 14, 15, 18, 19, 21, 22, and 25, out of nineteen cases in which pain was a prominent factor. Of 11. (those relieved of flowing) there were seven cases, Nos. 4, 5, 8, 12, 30, 31, and 32, out of twenty-three cases in which flowing was a promi- nent symptom. Of 111. (those improved in general health and ability to work) there were twenty-one, Hos. 1, 3, 4, 5, 6, 9, 11, 12, 15, 17, 18, 20, 21, 22, 23, 24, 27, 29, 30, 31, and 32, out of twenty-five cases where relief was possible. Adding these figures together, and subtracting twelve for numbers inserted more than once, and we have twenty-seven as the number that received symptomatic benefit. The remaining eight of the thirty-five, Hos. 7, 10, 16, 26, 28, 33, 34, and 35, come under heading IY. as having received no permanent benefit. If we analyze the eight cases of IY. we find that four of them may be classed as having received temporary relief. Hos. 10, 26, and 33 were relieved while under treatment, but became as bad as ever when the treatment was stopped. Ho. 7 complained only of sterility. Looking now at temporary symptomatic benefit, we may in- clude the entire forty-four cases in the tables. Of the thirty- five just considered we found there were four who were not benefited at all either permanently or temporarily. In the remaining nine of the forty-four, Hos. 36 to 44 inclusive, three received no benefit (they were Hos. 39, 41, and 44), and six, Hos. 36, 37, 38, 40, 42, and 43, were benefited. That is, thirty- seven out of forty-four cases treated, or eighty-four per cent, experienced relief of some sort as a result of electrical treat- ment. It must be taken into account, in a discussion of these figures, that the patients were treated for the most part at an out-patient clinic. Many of them, better treated at home, were obliged to travel long distances and await their turn for treat- ment, and then go home, often after a tedious ride in the cars and in inclement weather. To sum up, seventy-seven per cent of the thirty-five cases re- ceived permanent symptomatic benefit, and eighty-four per cent of the forty-four cases received temporary symptomatic benefit. As regards particular symptoms, two patients, Hos. 23 and 43, were afflicted with a profuse watery drain that was constant and required the use of a napkin. The electrical applications failed to relieve this permanently in either instance. In one, Ho. 23, it relieved temporarily. One patient, Ho. 24, has developed a 8 burrage: electrical treatment oe watery leucorrliea lately, a year after ceasing electrical treat- ment. Nos. 23 and 33 suffered with the uterine cough spoken of by French writers ; galvanism relieved this in a very marked degree in both. No. 23, who had been in the care of a promi- nent practitioner in town, had made use of nearly every known remedy without result; the cough was entirely cured by gal- vanism. Palpitation, a common symptom in fibroid cases, and not confined to those suffering with anemia from loss of blood, is favorably affected by galvanism. Glancing over the results obtained, from an anatomical stand- point I confess to a feeling of disappointment. I have main- tained a constant sharp lookout for miracles in the way of sud- den disappearance of tumors and marked diminution in size, but as yet have failed to observe any. I do not deny that fibroids sometimes undergo rapid absorption without the aid of electricity. It has been my lot not to see any such. I have, however, seen masses of inflammatory exudate disappear under electrical treatment with a celerity that was almost miraculous. Twenty-five of my cases, or seventy-one per cent, remained stationary in size. Assuming that fibroids if untreated will in- crease in size, we are justified in the conclusion that galvanism has an inhibitory effect on the growth of a majority of tumors. Until we know more of the conditions that favor increase or diminution in the size of these tumors, the laws of their patho- logical growth, we cannot say more. Temporary decrease in size was noted in nine cases, or 25.7 per cent. The decrease was proved to be temporary in six, and the remaining three were lost sight of in four, eight, and eight months respectively. The tumors in my series that increased in size were mostly large multiple growths, and dense rather than soft. They were seven in number, or twenty per cent. The increase in size was in no instance very great. Those that remained of the same size were interstitial and softer.] I have seen individual nodules reduced a third in size follow- ing puncture—e.g., No. 3. Large fibroids are seldom single. Looking over the symptomatic results, we see a highly satis- factory showing. Of the cases in which pain was a prominent symptom sixty per cent were permanently cured and a con- siderable portion of the remaining forty per cent were tempo- rarily relieved. Of those in which flowing was an important FIBROID TUMORS OF THE UTERUS. symptom, only thirty per cent were permanently cured, al- though a much larger percentage were temporarily benefited. I am aware that this low percentage of cures in the hemor- rhagic cases does not coincide with the results obtained by other observers. It seems to me that galvanism affects flowing in fibroids in two ways: first, by its tonic effect on the blood ves- sels and nerves of the pelvis; and second, by direct effect on the endometrium. As regards the first, galvanism is of great benefit in my experience. It generally regulates the flow in time, but in most tumors is not potent enough to check a de- cided hemorrhagic tendency. As to the second, we have seve- ral factors to consider—the size and shape of the electrodes, the duration of the treatments, whether the electrode shall be moved about, and, if so, how often, the intensity of the current, etc. But chief and foremost is tbe possibility of making a dry- ing galvano-caustic application to the entire bleeding surface ; for it is taken for granted that the source of hemorrhage in fibroids is a condition of endometritis of the entire uterine cavity—a thick, spongy, bleeding membrane or an atonic, thin membrane filled with venous radicles. Now, with a patulous os externum and a straight canal of only three inches in length, it is, in my experience, an impossibility to go over every portion of the walls of the uterine cavity with any electrode or series of electrodes made. When the uterine canal makes a sharp turn and is from four to eight or nine inches in length, the absurdity of trying to reach all parts of the interior is at once apparent— this even supposing the external os to be large; if it is small the difficulty is increased. It is a mechanical impossibility to guide the tip of a flexible electrode after it has gone round a corner in a tight canal; a rigid electrode cannot be passed. A con- siderable portion of fibroid tumors are so distorted that no intra- uterine treatment can be given. To this fact in part may be attributed the comparatively small percentage of cures of flowing in the cases presented. The cases that were treated most care- fully, with approved electrodes and high intensities, had a return of endometritis, just as we find is the case in those fibroids that have been curetted. Intra-uterine treatment with galvanism, where feasible, has the advantage over curetting that it does not subject the patient to the discomfort and risks of etherization, and is followed by no systemic reaction, which is often observed after curettement, especially in large tumors. Where the uterine 10 BURRAGE ; ELECTRICAL TREATMENT OF interior is easily accessible cnrettement is more thorough; where it is not, electrical application is, in my opinion, the best means of local and general treatment. It far outranks topical applications of carbolic acid, iodine, etc., and is more effective and preferable to ergot and hydrastis, as it has a beneficial in- stead of a deleterious influence on the digestive organs and the system at large. Many of my cases were helped by galvanism after months of fruitless dosing with ergot and other drugs. Galvanism relieves for about the same time as curetting, allow- ing for its diminished thoroughness. I want to call special attention to Case No. 8. Here a submucous, pedunculated fibroid, one and a half inches in diameter and having a pedicle three eighths of an inch through, springing from the fundus uteri, was made to present at the external os as a direct result of two intra-uterine galvanic treatments of eighty and eighty- five milamperes positive. The pedicle was then cut, the tumor delivered, and the patient recovered from her flowing. She had previously had a trachelorrhaphy performed at one of our leading hospitals, and later on had been curetted by a well-known operator, without the presence of the polyp being detected. Here is a good place to speak of the alleged danger of electri- cal treatment. Some abdominal surgeons have said that it causes abscesses and adhesions. It has done neither in my experience. It is contra-indicated in but two conditions, and those are preg- nancy and the presence of acute inflammation. In a paper on the treatment of pelvic inflammation with electricity, pub- lished in the Boston Medical and Surgical Journal of June 16th, 1892,1 cited a case of acute pelvic inflammation that I once treated experimentally with galvanism. She had salpingitis, confirmed by abdominal section. Her symptoms were aggra- vated by the electrical treatment. The proper application of electricity in the diseases of women is absolutely without danger, even in the presence of pus in the pelvis. I have treated a num- ber of cases with such a condition for months, and later operated on them and removed the disease. I recall one case in particular, and with your permission will outline it in brief. M. P., 39 years old, the mother of two chil- dren, proved on operation to have disorganized tubes and ovaries with abscesses on both sides. She was much benefited temporarily by both intra-uterine galvanism and bipolar vaginal faradism. She was under treatment a year, and had sixteen treatments FIBROID TUMORS OF THE UTERUS. 11 ■with galvanism (P. 8, N. 8, 40°-70°) and seven treatments with faradism (M. 70°-100°), and then consented to operation. Some of the patients having pus in their Fallopian tubes are very sensitive to galvanism, but they are not, in my experience, uniformly so, and I cannot agree with Apostoli that electricity is of value in diagnosing this condition. I shall refer to this matter again. A word as to the claim that electricity causes adhesions. By reference to my records I find that I have opened the abdomen in eight patients whom I had previously treated for longer or shorter periods with galvanism. In six of the eight, well- defined adhesions were to be made out by bimanual examina- tion before the patients were treated with electricity, and the adhesions were found when the abdomens were opened. I have found just as extensive and as strong adhesions in patients on whom no electricity had been used. Of the other two cases, one, No. 10 in my tables to-night, showed no vestige of an adhesion. The other was most interesting for two reasons : there were no adhesions, and, although extremely sensitive to galvanism, there was no pus present. The facts are these : I. F., 29, married and the mother of three children, had a lacerated cervix and prolapsed tubes and ovaries. There was great tender- ness on light pressure in the region of the right tube, this symp- tom having been present two years before, previous to the birth of her last child. I had seen her myself at that time and had noted the condition carefully. She was treated with vaginal galvanism for two months, receiving treatments as follows: N. 5, 20°-25° ; P. 1, 25° ; bipolar vaginal faradism F. 2, 40°. Hav- ing at that time just read Apostoli’s article on the diagnostic value of sensitiveness to galvanism as an indication of the pre- sence of pus in the tubes, I was on the lookout to test the prin- ciple. Here seemed to be a suitable case. Mrs. F. could not tol- erate the galvanism, even in the small dose of 20°; she was not relieved of great pain in the lower abdomen by faradism, except very temporarily. I diagnosed pus tube and operated. On opening the abdomen I found small, prolapsed, cystic ovaries, and tubes that to every appearance were perfectly normal. There was no adhesion of any sort. She was entirely cured by curet- ting the uterus, free puncture of the ovarian cysts, and hystero- pexy. (Continued on page 20.) 12 BDRRAGE : ELECTRICAL TREATMENT OF | Case No. N ame, age, social condition. Pregnancies. ■ Description of tumor. 1 Depth of uterus at 1 beginning, in cm. Flowing. Pain. 1 M. L., 35, m. 3 children, 1 abortion. Multiple, nearly filling pelvis; hard; a nodule at each cornu; mobil- ity limited; lacerated cervix and perineum. 11.5 Profuse at regular periods; 17 nap- kins. Constant pain in right groin for 6 years; dys- menorrhea. 2 E. M., 34, m. 1 child, 13 years. 0 abortion. Small, in posterior wall; retroversion; mobil- ity limited. (Ether examination.) 7.9 Scanty; periods regular. Constant pain across abdo- men; cramps first day or two of catamenia. 3 E. H., 32, s. Multiple, rising out of pelvis; hard; nodules to right and behind; fundus in front and to left. (Ether examination.) 10.2 Regular; 5 days; 6 to 10 napkins. Pain across ab- domen for sev- eral months; cramps with catamenia. 4 D. F., 24, m. 0 children, 1 abortion at 3 mos. 3 years ago. Multiple, nearly to um- bilicus; large masses behind; fundus in front and to right. 12.2 Profuse, every 3 weeks, since abortion 3 years ago; irregular. Dysmenorrhea 3 years; constant pain in left low- er abdomen. 5 M. L. P., 46, s. Small, interstitial; sym- metrical; retrover- sion; uterus fixed. 9.2 Excessive flowing with periods for 5 years; irregular; 3 weeks; 50 to 75 napkins; lasting two weeks. Cramps with flow 6 M. F., 48, m. 5 children, youngest 8 years; 1 miscar- riage at 6 months. Small, interstitial; fun- dus forward on blad- der; cervix in hollow of sacrum and ante- flexed; symmetrical. 10.5 Severe flowing at periods for 1 year; 2 weeks’ flow; 12 napkins. No pain.. 7 H. S., 43, m. 0 children, abortion at 6 weeks 9 mos. ago. Multiple; size of a co- coanut; 2 lobes; mo- bility good. (Ether examination.) 8.5 Regular; 12 nap- kins. 8 C. S., 40, m. 7 children, youngest 6 years; 0 abortion. Small, interstitial; also pedunculated submu- cous If inches by 1) inches; salpingitis right side. (Ether examination.) 9. Bad flowing spells for 2 years, a sheet at a time. Pain in right groin and low- er abdomen for 7 months. 9 A. C., 27, s.; col- ored. Interstitial, cocoanut; rising out of pelvis; rather soft; symmet- rical. (Ether examination.) 9.5 Scanty; regular... Cramps across abdomen. 10 M. McK., 40, s. Small, in anterior wall, size of marble; ante- flexion. (Ether examination.) 7. Scanty; regular; 1 day. Constant pain in back and ab- domen for 10- years; dysmen- orrhea. FIBEOID TUMOES OF THE UTEEUS. 13 General condition. Number of months under observation. Number of months from first to last treatment. Number of treat- | ments. Description of treatments. Results. Depth of uterus at end, in cm. Of stout build; ner- vous ; a great suf- ferer with pain. 30 23 50 Intra-uterine, 60°- 130°; P. 28, N. 19. Vaginal faradism, F. 3. Much relieved of pain; not per- manently. At end of 1 year tumor a little smaller and mo- bility good; one nodule pedun- culated. At end of 24 years tumor larger, slightly. Flow- ing about the same. 12.8 Fair 5 5 8 Intra-uterine, N. 5. 32°-55°; P. 3, 55°-70°. Flowing increased. Dysmenor- rhea relieved. Constant pain relieved for 3 weeks at a time. 7.6 Mental depression; an inmate of in- sane asylum. 8 8 21 Intra-uterine, N. 19, 50°-120° Vaginal punc- tures, N. 26° 6 minutes, N. 80° 5 minutes. At end of 8 months mass re- duced one-third. Mental con- dition improved. Pallor and anxious expression of countenance; a great sufferer; chronic constipa- tion; girth of ab- domen, 80 cm. 24 16 49 Intra-uterine, N. 13, P. 18, 60°- 1T5.° Vaginal punc- tures, N. 14, P. 1. 65°-120°. Vaginal faradism, F. 3. Intra-uterine, P. 29, N.2,50°-125°. At end of 8 months uterus mea- sured 14 cm. and girth of ab- domen 81.5 cm. At end of 2 years exactly the same mea- surements. Flowing less. Pain and dysmenorrhea relieved. Catamenia regular. 14. In bed for 2 or 8 days with each flowing; unable to go up-stairs; iron and ergot for 8 months made her worse. 34 10 31 In 2 months had the best period in 5 years. In 3 months had gained 20 pounds in weight and not confined to bed with flow; able to go up- and down-stairs. 1 year, flow of 20 napkins; uterus freely movable; no cramps 3 years, flow of 20 napkins; regular to a day; has to keep still 2 days. 8.9 Of large frame; poorly nour- ished; unable to work; had taken ergot for 9 mos. without effect. 25 6 16 Intra-uterine, P. 13, 40°-125°; N. 3, 30°-60°. After three treatments could do all her work except the wash- ing. After 6 months, flow re- duced one-half. MenopauseIn 1| years. Sterility her only complaint. 4 3 16 Intra-uterine, N. 16, 50°-125°. At end of 4 months mass not as large. 7.5 Blanched and weak; trachelor- rhaphy 6 months ago and curet- ting 1 month ago. 25 4 2 5 Intra-uterine, P. 2, 80°-85°‘ P. 2, 60°-120°; N. 3, 15°-100°. After 2 positive intra-uterine treatments the pedunculated fibroid appeared at os exter- num and was removed with scissors. Salpingitis the im- portant factor. Refused ope- ration. Too weak to take elec- trical treatment. After 1 year flow regular, not profuse. General strength very good. 8.8 Unable to stoop; had noticed lump in abdomen for 4 years; girth of abdomen, 68 cm. 26 23 40 Intra-uterine, N 39, 60°-90Q. Abdominal punc- ture, 125° 10 minutes. F. 1, 40 F. 4 min- utes. At end of It months girth of ab- domen 69.5 cm.; at end of 16 months girth of abdomen 74.5 cm.; at end of 24 months girth of abdomen 74.3 cm. Patient much stouter, however. Tu- mor, I think, same size. Re- lieved of cramps. Able to stoop. 11.3 A great sufferer with dysmenor- rhea; frequency of micturition. 13 1 18 Intra-uterine, N. 6, 48°-70°. Vaginal, N. 12, 45°-80°. At end of 1 month fibroid small- er and dysmenorrhea some- what relieved. Dudley’s ope- ration for anteflexion. 1 year after cessation of treatment fibroid larger, dysmenorrhea worse. Myomectomy. 14 BITERAGE : ELECTRICAL TREATMENT OF | Case No. Name, age, social condition. Pregnancies. Description of tumor. Depth of uterus at beginning, in cm. Flowing. Pain. 11 ◄ 2 children, youngest 26 years. Subserous; cocoanut; from left wall; dense; salpingitis. (Ether examination.) 9. Regular; 3 to 6 days; 6 to 10 nap- kins. Pain in left side and back for 6 months; severe dysmenorrhea. 12 A. R. N., 39, s. Multiple, nearly filling pelvis; one mass size of small cocoanut on left, another, size of orange, on right; mo- bility good. (Ether examination.) Bad hemorrhage 1J years ago; flow increased for 3 years; irregular; 9 days; 50 nap- kins. Slight dysmenor- rhea. 13 M. B., 42, m. 2 children, 13 and 11 years; no abortions. Interstitial, fetal head; asymmetrical; larger on right; mobility good; lacerated cer- vix. 10.8 Periods every 3 weeks; more flow every other peri- od; not profuse. Constant severe pain in back; dysmenorrhea. 14 M. H. L., 50, w.; colored. 1 child, 1 abortion. Multiple, filling pelvis; dense; immovable; cervix so distorted that probe cannot be passed more than li inches. Profuse flowing at periods for 4 years; 8 days’ flow every 2 weeks; 8 nap- kins a day. Constant severe pain in back, worse on walk- ing; also pain in abdomen. 15 E. A., 30, m. 2 children, 1 abortion. Interstitial, fetal head; dense; symmetrical; mobility good; lace- rated cervix; salpin- gitis. Flow rather pro- fuse every other month; regular. Pain in left side and back; bear- ing-down feel- ing; dyspareu- nia. 16 E. F., 33, m. 1 child, 7 years. Interstitial, cocoanut; rather soft; more on left; mobility good. 10.2 Rather profuse and prolonged; regu- lar; 28 days. Constant bear- ing-down pain in abdomen; 3 attacks of bad abdominal pain in last 10 months. 17 S. T., 41, m. 3 children, 1 abortion. Large interstitial, ris- ing above umbilicus; umbilical hernia. 20.5 Profuse; regular; watery leucor- rhea; 10 napkins a day and 4 nap- kins a night. 18 S. H., 38, m. 4 children, 13 to 5 years; 0 abortion. Interstitial, cocoanut; dense; freely mov- able; lacerated cer- vix. 13 Profuse flowing for l£ years; a nap- kin every hour when bad; of 9 days’ duration; regular every 26 to 30 days until li years ago. Dysmenorrhea for l.i years, in- creasing in se- verity. 19 K. C., 32, m. 0 children, 1 abortion at 9 weeks 2 years ago. Subserous, orange; to right and behind fun- dus; mobility good. 7.8 Rather profuse; regular. Constant pain in left side and back for years. 15 FIBROID TUMORS OF THE UTERUS. as a. A « "S 4-> c3 o ei St >1-1 <1> o a o General condition. SS-g «h co a of-® s 4-3 o Description of treatments. Results. 2 O' V a O S ■§ X? Cl B S S22 |§ ia’2- Sz; £ Q Fat and hysterical; 14 9 39 Intra-uterine, N. Unable to determine exact size unable to do 17, 35°-65°. of tumor at end of treatment much work; hy- persensitive. Vaginal. N. 7, P. without anesthesia; think it 2, 35°-50°. Vaginal faradism, F. 13, F. 50°-100°. was the same. Sensitiveness relieved temporarily. Dys- menorrhea relieved. Able to Anemic; of stout 24 do more work. 11 20 Intra-uterine, P. Flow relieved; 20 napkins; not build; confined 2, N. 7, 40°-70°. Vaginal puncture regular. Able to work after 3 to bed with each months’ treatment. At end of flowing. under ether by 1 year tumor larger; at end of Dr. Baker, 125°, 2 years tumor larger. N. 15. Vaginal gal van- ism, N. 8, 35°- 60°. Fair; constipated.. Faradism 3, F. 70. 18 17 61 Intra-uterine, P. Periods regular every 4 weeks. 11. 36, 60°-90°; N. 19, 40°-75.° Bipolar vaginal faradism, F. 6, Flow a little increased in amount. Pain in back uni- formly relieved for 2 days af- ter each treatment, then to Weakness from ex- 100.° return. Tumor same size. 18 18 29 Intra-uterine, P. After 8 months tumor smaller, cessive flowing; 19, N. 3,50°-100°. after li years tumor same size painful micturi- Vaginal, P. 4, 50°- Flowing, 8 napkins a day for 3 tion and defeca- 60°. or 4 days instead of 8 days tion. Bipolar vaginal faradism, F. 3, every 3 weeks. Constant pain relieved. Of stout build; neu- 75°-100°. 8 7 13 Intra-uterine, N. At end of 8 months tumor re- rotic. 7, P. 2, 40°-70. Vaginal, P. 2, N. 1, duced to size of large orange. Flow as before. Pain relieved. 40°. Improved strength. Faradism, F. 1, 60°. Intra-uterine, N. Much pulled down 18 3 13 At end of 3 months tumor small- 12.2 by attacks of 11, 40°-70°. er. Flow decreased, but every 3 weeks. Pain relieved. No abdominal pain; Vaginal, P. 1, 35°. frequency of mic- Faradism, M. 1, attacks of abdominal pain. 50°. At end of 1 year tumor larger. Flow profuse. One attack of abdominal pain. Very mise- rable. Hysterectomy (Baer’s Annoyed by size of 18 4 26 Intra-uterine, P. method). Recovery. At end of 5 months girth of ab- tumor; watery 17,100°-175°; N. domen 108 cm.; at end of 1| drain and gene- ral weakness; girth of abdomen 9, 75°-200°. years girth of abdomen loi cm. Increase of fat in parie- tes; had worn an umbilical 103 cm. truss for 6 months. More room in abdomen. Increased strength. Watery drain and flow same. Increased pain for S weeks after Large, stout; very 12 2 8 Intra-uterine, N 4, P. 2, 60°-100°. nervous; easily last treatment. At end of 1 startled; alco- Vaginal, P. 3. 15°- year tumor same size. Flow- holic (?). 70°; F. 3, 70°. ing and pain 4 months after cessation of treatment; an abortion 6 months after. Pe- riods regular (26 to 30 days) 4 to 6 napkins, since. Able to Fair work more. 18 15 41 Intra-uterine, P. At end of 6 months tumor small- 9^ 23, 35°-150; N. er; at end of 1) years tumor larger. Flow increased in 11, 50°-100°. Vaginal, N. 2, 50°- 80°. amount and periods prolonged Pain relieved for a few days at Puncture, N. 1, a time. On the whole mnoh 50°; F. 4. less pain than years ago. 16 BIJRRAG-E : ELECTRICAL TREATMENT OF Case No. ! Name, age, social condition. Pregnancies. Description of tumor. Depth of uterus at beginning, in cm. Flowing. Pain. 20 A. R. H„ 38, s. Subserous; goose egg, from right side of fun- dus. (Ether examination.) 8.2 Rather profuse; regular. Dysmenorrhea; moderate. 21 J. S. R., 43, m. 2 children, 19 and 17 years; 0 abortion. Multiple and intersti- tial, filling cavity of pelvis; large lobe be- hind. 8.6 Regular; normal.. Frightful cramps with periods, causing her to give up work for 6 years. 22 F. M. S., 36, s. Subserous; hen’s egg, in left lateral wall of uterus; retroversion; mobility good. (Ether examination.) 9.5 Profuse for2 years; catamenia every 23 days; 50 nap- kins. Constant pain in back; unable to turn over in bed. 23 M. H. H., 40, m. 0 children, 0 abortion. Interstitial, cocoanut; mobility limited. (Ether examination.) 9.3 Menorrhagia for 6 years; flow every 3 weeks; 30 to 40 napkins; shreds and clots; a clear watery discharge between periods. Dysmenorrhea for first 3 days. 24 M. A. S., 36, s. Multiple, large, to edge of ribs; 2 lobes, large, and smaller above and between. (Ether examination.) 19. Menorrhagia for 2 years; every 3 weeks; 21 nap- kins. Dysmenorrhea.. 25 N. O’H., 30, m. 1 child, 10 years; 0 abortion. Interstitial, orange; tu- mor more on left; mobility good. 8.4 Menorrhagia for 2 years; every 30 to 32 days; 5 days; 20 napkins. 26 M. C., 38, m. 4 children, youngest 12; 0 abor- tion. Interstitial, small; sym- metrical, except slightly larger on left. (Ether examination.) 8.9 Profuse flowing every 4 weeks for 9 months; 40 nap- kins; 4 to 5 days. 27 E. P. C., 35, m. 3 children, youngest 9; 0 abor- tion. Interstitial, small; mostly in posterior wall; retroversion; la- cerated cervix; mass in cul-de-sac (tubo- ovaritis). (Ether examination.) 9.2 Profuse flowing off and on for 7 years; nearly constant; free- dom for 3 mos. once during that time. 28 H. B., 43, m. 3 children, youngest 15; 1 abor- tion at 8 months. Interstitial, small; in posterior wall from external os to one-half inch of fundus; lace- rated cervix and peri- neum; retroversion. (Ether examination.) 9. Profuse flowing for 3 months; me- trorrhagia; cata- menia always profuse. FIBROID TUMORS OF THE UTERUS. 17 General condition. £ P is o O c3 s t <4-1 o XJ u || A § jg jS lo as-g ■geg a cj£ 822 A