SPOTTED OR CONGESTIVE FEVER. SPOTTED OR CONGESTIVE EEVER. By C. B. COVENTRY, M. D., Of Utica, N. Y. ALBANY: VAN BENTHUYSEN & SONS' STEAM PRINTING HOUSE. 1867. SPOTTED OR CONGESTIVE FEVER. During the past season (1865 and 1866), a disease made its appearance in the county of Oneida, which was new in that sec- tion of the country, though it had formerly prevailed in some of the New England States, and more recently appeared in some places in Pennsylvania and different parts of our own State, and which, during its prevalence in Massachusetts and Connecticut, was known by the name of spotted fever. The name of spotted fever no doubt arose from the circumstance that in many cases the body assumed a spotted or mottled appearance. These spots were not always present, and varied much in their character. The only work on the»subject which I have been able to find is a small volume published by Elisha North, in 1811, and several articles in the medical journals and papers about the same time.* In an article by Dr. Samuel Woodward, first published in the American Mercury, a newspaper published at Hartford, Ct., and republished in this work of Dr. North, he says: "At a meeting of the councillors of Massachusetts Medical Society, held on the 7th day of February, 1810, it was voted that a committee be appointed to collect information respecting the history and treatment of a malignant disease, commonly called spotted fever, which is now prevailing in the county of Worcester, and which has prevailed within five years past in Hartford, Connecticut, and Providence, Rhode Island." Dr. Fisk, a member of the committee, says: "Upon the appearance of any new disease, every reflecting physician will endeavor to class the non-descript with some disease which he has seen, and by comparing its leading features, be enabled to adopt a practice which gives some promise of suc- cess. How far it has been done in this disease I know not, as I have seen no treatise on the subject. If it has been attempted, the result I apprehend has proved fallacious." "In a close atten- tion to it for fourteen days, at Rutland and elsewhere, I have been led to the opinion that though no class yet identified will claim * Since the above was written, several articles have appeared in the Journals, and an article by Dr. Burr in the Transactions of the New York State Medical Society. 4 the monster, yet under some genus it may find a settled affinity." Our standard works on practice have little or nothing on the sub- ject, or if mentioned at all it is simply referred to as a form of typhus or typhoid fever. It is sufficient to say that no intelli- gent physician who had a personal acquaintance with the disease, could possibly confound it with either typhus or typhoid fever. It is only in the few cases where the disease is long protracted and the system exhausted that there is any resemblance to typhus or typhoid fever. Different writers have differed materially as to its classification, some, as has been seen, speak of it as a form of typhus, and term it typhus petechialis. North considers it as a new form of fever. Dr. Fisk says it has a strong analogy to scarlatina anginosa. By some it was considered a malignant remittent fever. A similar disease is described as prevailing in Geneva, Switzer- land, where it was known by the name of malignant cerebral fever-not contagious. In this disease it is said, with the greater number of patients who died in twenty-four hours, the body was covered with violet spots at the moment of death or a little after, and sometimes before death. On opening the bodies of the dead no morbid alteration of the viscera was found, only a turgidity of the cerebral vessels. There can be no doubt the same disease was prevalent during the last two or three years in this country under different names, sometimes confounded with cerebro-spinal meningitis, sometimes designated as congestive chills. Dr. Burr* © © © describes the disease as it prevailed at Carbondale, Pa., in the winter and spring of 1861, under the name of cerebro-spinal meningitis, or spotted fever. Cerebro-spinal meningitis, as we shall see, is one of the many and perhaps the most fatal form of this Protean disease, inflammation of the meninges of the brain and spinal cord is but one of the many forms of the disease, and we must look for some more com- prehensive term by which to designate it. If we look alone at the symptoms, I apprehend it would be impossible to place it in any known nosological arrangement. If, however, we look at the pathology, I think there could be no hesitation in placing it in the class of congestive fevers, so ably described by Dr. Armstrong. Congestion is the one prominent condition, always present, but confined to no one organ, and the symptoms, as we shall see, vary- ing with the organ affected and the severity of the attack. In all * Transactions of the Medical Society of the State of New York, 1865. 5 severe congestions the function of the part or organ affected is impaired, and if not promptly relieved, and the patient survives, it is followed by inflammation anti fever. If the brain and spinal marrow is the seat of the congestion, we have spasms, coma, and delirium, and if not relieved, followed by inflammation and all the symptoms'of cercbro-spinal meningitis; if the stomach, we have obstinate vomiting; if the intestines, we have diarrheea or obstinate constipation; if the heart and large blood vessels, we have irregu- larity of the pulse, oppressed breathing and general distress; if the limbs are the seat of the congestion, we have pain, swelling, tenderness, resembling / phlegmasia. As has been seen, the symptoms vary, not only with the organ affected, but with the severity of the attack, from a slight indisposition to a disease causing death in six, twelve or twenty-four hours^ogib 'mlimig A Dr. Woodward says: "The disease appeared in Winchester, Ct., in April, 1809. Young people under twenty-one were most liable to it, and among adults, females were more liable than males; no age or sex was, however, free from attacks. It assumed in different subjects all grades of disease, from a mild fever to a £ ooidi io owl Iasi odi gnimb inolnvoiq 11 The symptoms were various according to its inveteracy. It attacked with chills, lassitude, great prostration of strength, eyes red and watery, pupils dilated in some cases, in others, small, as in dying persons. Often delirium, with exquisite pain in the head, great anxiety at the stomach, with tossing of the body, nausea, and often troublesome vomiting. A pain and lameness of the limbs often ushered in the disease; there was soreness of the flesh and generally spots on the skin."^)nB 9£{j lo asmiinsm odi lo Dr. Bestor says: "The patient is for the most part attacked with a sense of extreme coldness, sometimes with shivering, at other times with rigors, accompanied with pain in the head, usually over one or both eyes, severe pain in the extremities- sometimes in a toe or finger, but most commonly in the legs, knees, thighs or arms. An alarming prostration of strength, delirium or coma. The eyes often red or suffused, pupils enlarged, double or triple vision, in some patients a total blindness for the first twelve or twenty-four hours: difficult deglutition, distressing pain and anxi- SYMPTOMS. *Note.-North on Spotted Fever. Page 112. 6 ety of the stomach, attended with nausea, and for the most part with vomiting." Dr. North says: "The disease may be divided into two varieties, the distinction, however, is in the severity of the disease." If there is any one symptom which may be regarded as premonitory of the disease in all its forms, it is a sore throat. I have observed this in so many cases and found so few exceptions, that were it not an attendant on so many diseases I should consider it a pretty sure premonitory sign of this complaint, and yet this affection is so slight that few patients mention it unless they are questioned about it. The symptoms of the first species are a great and surprising loss of strength, which is a constant and prominent symptom. A cold surface, sometimes accompanied with chills, sometimes not. The extremities in the cold stage appear of a purplish or leaden color. Violent pain of the head, and many times of the limbs, are among the first symptoms, sometimes the one, sometimes the other, are first attacked. When the pain commences in the limbs it soon mounts up to the head. Distress about the precordia, violent and extreme; also numbness of the extremities are often added to the above list of symptoms. The breathing is pften laborious and attended with frequent sighing. Syncope sometimes occurs. The pulse in this and all the varieties and stages of the complaint is soft, weak, and never hard, though it is sometimes slow, even slower than in health; it is often intermitting, fluttering or totally absent, even in cases in which the patient has ultimately recovered. The tongue is usually covered with a white coat, but in some bilious cases it is of a brownish hue; sometimes it has been observed to have a bloodless appearance. The urine deviates but little from health, except a hysterical flow, which sometimes has been observed to happen. There is loss of appetite, sickness at the stomach and vomiting. The worst form the disease assumes, particularly in children, is that of coma, or cholera morbus. It frequently assumes the form of violent mania at the time or within a few hours of the attack. Sometimes delirium is among the first symptoms, some- times coma, and many times petechia. Unless the patient recovers, he usually dies within the first twelve, twenty-four or forty-eight hours. In those who recover, the disorder puts on, cither before or soon after forty-eight hours, the form of a mild typhus of uncer- tain duration. Among the more unusual symptoms are mentioned dilatation of the pupil, blindness, double vision, a drawing back 7 of the head, with a kind of clonic spasm of the muscles of the neck, an erysipelatous inflammation of the limbs, swelling-like rheumatism of the joints, paralysis of an arm or leg, or both, car- buncles and buboes, strangury and violent pains in the fingers and ... Vf.rn UUJ 1' • / luJi 111. >ll£ J I Oi DtJU IfrMH 1 .III V I.III III11 I Jj if itiis i ill / > j 11 i t • irrrn r Let us compare the above with the symptoms of congestive fever, as given by Dr. Armstrong : oa at oonronB Bia® Jo-£ dhb janiiqmoo emj io ngia yioimomsiq General WJ] jj ( 1. More or less reduction of the heat of the skin. 2. More or less prostration of the muscular strength. 3. Diminution or oppression of the heart's action. 4. More or less lassitude and torpor. 5. Disturbance of the function of some important organ. The functions of the skin are disturbed. The internal organs undergo certain changes, and these take place in the following order: 1. Heart and large adjacent vessels. ,X; j j mi nanom 2. The lungs and mucus membrane of the bronchia. 3. The brain or spinal marrow; odT .gfnoiqm^e 'io toil ovodn 4. The liver and vessels associated in its circulation. * Particular Symptoms. ^nB fli Suppose the congestion to exist in, first, the heart and large blood vessels, it is Uien denoted by the following symptoms : 1. Some uneasiness in the region of the heart. ° , navoo vlmuaw ei ougnot 2. A deficiency of power in breathing, ^gj^^d £ q0 g- p . 3. A small, weak and irregular pulse, or oppressed pulse. If it exist in the lungs or bronchial lining, it is characterized , . Hbirg^mrnwos n^rnw tvfoiiTii9iiwavd uiqooxo jlfucni by : jrn jjhk n .LHioJr. qilj jb d^onnoia ,9iiJ9qqB io eaol sr aiadT .noqqjvL of 1. A peculiar color of the lips and cheeks. The lips are either of a violet color, a plum color or leaden color. r.-innwwn rr ^uoTorn irmonaio tnmoo io Judi si fn9ibhd9 2. A labored or short, weak and frequent respiration. nTOir Jo omn jpsioiv io nrioi oil! It the congestion is in the brain or its appendages, we have : 1. Confusion, immobility or indifference to surrounding objects, .i;rrrooFiq mif vinminnB jmSbo abinir or giddiness, with pain. . , . . - ® * • . , 1 ifc'irt odi mdiiw ^9ib vllnneu sd 2. An intoxicated or stunned or alarmed expression. 3. A blanched state of the conjunctiva, with watery appear- ance of the eye,. ci« 25 . ,, qy-i lira £ io cmoi adt ,8iuod Jdgio-vrioi i9Jie nooa It in the spinal cord or its membrane, we may have : jirormjn n wqmt8 adj giionrA .iioWwb nmi 1. General convulsions and partial spasms. Symptoms of Congestive Fever. 8 2. Wandering'pains and tenderness on the surface of the body. If in the live? and associate vessels, wo have : 2. dullness with fliiftilence in the epigastric region. 3. Some unoaMy sensation of a load or tightness or fullness in the region of the 1^¥.°^°* 81 rbovonoi ^liqmoiq ion li Dr. Armstrong says, this is an extremely dangerous affection, that he has knoWn some casbs to terminate fatally in one hour, in three hours, in four hours, and very often in twenty-four hours. He says, if you have produced a sttltb of excitement, the patient is generally going on well, if properly managed. If the conges- tion continue, and the brain, stomach and lungs are disturbed, the case will generally terminate fatally. If the excitement is imper- fect and the case put on the congesto-inflammatory character, it is very serious. If the*trunk bo hot while the extremities remain cold, with great disturbance of the lungs, the brain and liver, the case is mostly very serious. If the excitement is perfectly developed, the fever is 'either simple or inflammatory, and prog- nosis is to be given accordingly. It is most dangerous in infants, in old persons, and in women after delivery, and in persons labor- ing under much mental excitement. The disease, as it has pre- vailed in the city of Utica, has been comparatively mild, but few deaths occurring, and those mostly among children. It has, how- ever, been sufficiently severb and fatal to indicate the true character of the disease. In home parts of tile county it has been more severe, and 'MonsCqubntly the mortality greater. The symptoms were various; one of the most frequent and often the first to attract attention, was obstinate vomiting, particularly in children; frequently^here was slight indisposition 6f one or two days, when the patient was'suddenly "soiled"with most excruciating pain, often in the head,r but Sometimes in the chbst, ol' abdomen, or in a leg, foot or hand. ^Frequently they would wake from sleep, and cry out," Oh, my head* head 1" and'seem on the point of going into convulsions. In adults, if the attack is not severe, they often complain of severe pain in the head, which they represent as dif- ferent and more intolerable than anything they ever before experienced. At the same time the surface is cool and moist, the tongue covered with a slight, moist, whitish mucuS; the pulse is often nearly natural a^ ' to fbequehby, but soft and easily com- pressed. If the throat bo examined, the mucous membrane of the 9 pharynx will be found redder than natural, and the vessels con- gested, though the patients seldom complain of the throat unless their attention be drawn to it. Whatever may be the seat of the congestion, general prostration is a prominent symptom. When the meninges of the brain and spinal cord are the seat of conges- tion, if not promptly relieved, it is followed by inflammation, with all the symptoms of cerebro-spinal meningitis. Whether cercbro-spinal meningitis ever prevails as an epidemic independent of this complication is uncertain; it is, however, certain that it often occurs as one of the forms of this protean malady. We seldom find all the symptoms mentioned as occurring in any single case: the following which was the first case I met with, will illustrate some of them: On the evening of February 3, 1866, I was called to the child of Mr. R , about nine months old; I found her suffering from vomiting, with but little disturbance of the circulation-the child was teething. I made the ordinary prescription; next morning I was surprised to find that the vomit- ing still continued. I cut the gums, applied mustard over the stomach, and bathed the feet and legs in warm water, and directed some small powders of calomel and calcined magnesia. The next morning I was informed that my patient had a restless night. On visiting her in the morning, I was surprised to find she had great nervous excitement, general tremor as if on the point of going into convulsions, and the appearance of great agony. The pulse had become very frequent and irregular, the head was drawn back, the muscles of the neck rigid. On the third day the knees became swollen and inflamed. She died on the fourth day. Pathology. But few " post-mortem " examinations have been made in spotted fever, but those few are sufficient to show the identity with the post mortem appearances found in congestive fever, as described by Dr. Armstrong. Dr. Burr, in his account of the disease as it prevailed at Carbondale, Pa., says: "The principal lesion observed was intense congestion of the blood vessels of the brain and its covering, with evident traces of meningeal inflammation; the spinal cord was not examined." If the patient dies within a few hours, the only lesion found is intense congestion. If twenty-four or forty-eight hours have elapsed, there may be effusion combined with the congestion. Still later, there will be traces of inflamma- tion and deposition of coagulable lymph, and if the patient has Art. 7. 10 survived to a still later period, there will be softening and disor- ganization. Dr. Armstrong says the morbid appearances dis- played by dissection after death in fatal cases of congestive fever, are two, and sometimes a third occurs. 1st. An over accumulation of venous and arterial blood in the part, the function of which has been disturbed during life, and especially the veins, or 2d. An effusion of mucus or serous fluid according to the struc- ture of the part. In the brain and spinal cord, a serous effusion, in the bronchial lining, a mucus effusion, and in the intestines both a serous and mucus effusion. 3d. Sometimes there is an effusion of blood. Danielson and Mann* relate five cases of post-mortem examina- tions of spotted fever, but, unfortunately, they give no history of the cases, or state at what stage of the disease the patients died. The first was a boy ten years of age, whose case was strongly marked, and terminated in 22 hours; examination seven hours after death. On removing the cranium and dividing the dura-mater, there was discharged, by estimate, half an ounce of serous fluid. The dura-mater and pia-mater, in several places, adhered together, and both to the substances of the brain. The veins of the brain were tinged with a fluid resembling that discharged from between the membranes; and the substance of the brain itself was remarkably soft. In the stomach there were six ounces of fluid resembling coffee grounds, and its villous coat was nearly in a state of disso- lution. " The lungs •were darker than usual, otherwise all the viscera were in a healthy condition." The second examination was made twelve hours after death on the body of a girl five years old. Between the dura and pia-mater Was effused a substance resembling pus, both over the cerebrum and cerebellum, the veins of the brain tinged with blood and the hemispheres adhering together with considerable strength. The appearance of the stomach differed in nothing from the preceding case, only that the villous coat was not so tender. In the three other cases examined there was nothing peculiarly morbid, except that the veins and sinuses of the brain were found remarkably tinged with a very dark-colored blood. Dr. Burrf says not many post-mortem examinations were made during the epidemic. The principal lesion discovered waS intense •North on Spotted Fever, page 89. t Transactions of the New York State Medical Society for 1865, page 43. 11 congestion of the blood vessels of the brain and its coverings, with evident traces of meningeal inflammation. The spinal cord was not examined. Dr. Budlong, of Cassville, Oneida county, where the disease first appeared in the county, made a post-mortem examination of a case where the patient had lingered several months. He found softening and disorganization of the medulla, oblongata and base of the brain. Cause. It is probable that sporadic cases of spotted fever have occurred, but if so, they were confounded with some other disease. It is only when prevailing as an epidemic that the attention of the pro- fession has been called to it as a distinct disease; it consequently follows, that whenever it occurs in an epidemic form, there must be some general cause, which predisposes to this particular form of disease. Dr. North thinks it is attributable to the state of the seasons, and says "the seasons have been unusually cold and wet since the prevalence of the epidemic." Some have thought it had a malarious origin. Dr. Burr says, " Of the cause of this epidemic we know literally nothing." It is not contagious. In truth, it is like all epidemic diseases, though we suppose there must be some general cause; yet what it is we do not know. In regard to the immediate existing cause we have more evidence. Everything that weakens and exhausts the system tends to develop the dis- ease; hence we find that children and women, and persons exhausted by dissipation or disease, are the most frequent victims. Diagnosis. So varied and multiform tire the symptoms of this disease that no description, however graphic, will enable the practitioner to recognize its presence. To be known it must be seen; but the observant practitioner, having once seen and recognized this dis- ease, will not mistake it. No doubt sporadic cases have often been mistaken for other affections. I have known a well marked case of this disease, where, of three or four different physicians who had seen it, each gave it a different name. One said it was inflamma- tion of the brain, another called it apoplexy, another paralysis. When, however, it is known that the disease is prevailing as an epidemic, other diseases will be more likely to be taken for the one under consideration than the reverse. The most striking charac- teristics are the suddenness of the attack, the excruciating pain, * vfohjo? dioY w*>X odl lo spoilt)ctqxhT t 12 often shifting, sometimes in the head, sometimes in the hand or foot, and this with a moist, cool surface, and soft, compressible pulse. In some cases there will be petechia. I have seen it at the commencement of the disease, at other times later, and often not at all. When it affects the brain and spinal marrow, the symptoms arc more strongly marked: often spasms, the head drawn back and the muscles of the neck rigid, with a general expression of agony. Prognosis. When it prevails as an epidemic, this is undoubtedly a very malignant and dangerous disease. As it prevailed in the New England States in 1810 and 'll, it was not inaptly compared to the plague. Dr. Burr tells us that in the village of Carbondale, Pa., in the winter and spring of 1864, there were *400 deaths out of a population of 6000^ Dr. Elisha North, speaking of the dis- ease as it prevailed in Winchester, in 1807, says, "According to the best of my information, one-third of those who had it died." In reference to the prognosis in individual cases, much will depend upon the stage of the disease. If seen within the first 12, 24 or 48 hours from the attack, we may hope, even in the most violent cases, by prompt and judicious treatment, to save our patient, whilst on the contrary, if the first stage has been neglected or injudiciously treated, even the mildest cases may end fatally. If the vomiting is controlled, warmth and moisture restored to the general surface, the pulse becoming fuller and stronger, with a gradual abatement of the severe pain, we may consider our patient as doing well. If, on the contrary, the distribution of warmth is irregu*lar, the body becoming hot whilst the extremities remain cold-if, notwithstanding our ri n uotruiiiir noi OHffifO up ilk'ii "Of f f Hol r i r means, the disturbance of some important organ, as the stomach, the brain or lungs, continue, the case will usually prove fatal. If the excitement be perfectly developed, the disease cither subsides or assumes the form of simple inflammatory fever. If the excite- ment is imperfect, the congestion being but partially removed, the patient sinks into a typhoid condition of very uncertain duration. It is the fashion of the present time to deride the influence of med- icine and laud the efforts of nature, and this by some members of our own profession. In the disease under consideration, the expectant treatment will not answer. Active, energetic treatment is demanded, if you wish to save your patient. The prognosis is 13 influenced by the importance of the organ principally involved- that of the brain and spinal cord being most dangerous; also by the age of the patient, and his previous condition, it being most fatal in infants, in old persons, in women soon after delivery, and in persons depressed by mental anxiety dr deficient nourishment. Treatment. The treatment must depend upon the violence of the attack, the importance of the organ or organs implicated, and the period of the disease. The first or early stage of the more severe form of the disease, s ylbEddn^rtW.pimabiqo BB-simvoiq Ji mm/T ' is characterized by the tollowing symptoms: 1. A cold skin with a sense of chilliness, sometimes an actual qOoisqmoa yliqaai joa saw dr fITom; UIol ui gomTo Chill. . * rr zr .^birodWJ-iQ.onBiliv oni nt dead au sllod Tina-Ml - .oirmq odd 2. By a small, weak and easily compressed pulse, sometimes an absence of pulsation at the waist; the pulse when present often irregular. ® od d 'W 3. By a feeble and oppressed respiration. i.bafb di bud onw oedod lo-Dimd-uno r non# anoint vin io deed oat 4. By great prostration ot muscular strength. 5. By great topical disorder, which may be seated in the head, heart, lungs, bronchial lining, m the liver, stomach or intestines. ' • v x- vcpMia odTmoiI &mod -ip 4; The indications are to restore the balance ot the circulation nvcg ot TgpmjBOij auoimbm bim.mmo'ig vd (8o&bo motor/ Jeoni ohj between the venous and arterial system, and the surface and jmoa and omda Jain .oaT ii .vwao& pdjjjo. dalidw -.dhounq tuo internal organ; to relieve the pain and suffering, and try to cor. X -I t I X rrV • T k i rect the local derangement. Ibis is accomplished- i -n -P +k x- r +k i c i r i c 1. By exciting the action of the heart by stimulants. ... W odd Roaring inionoa.odi ot _boiotaoi 2. By exciting the skin by the external application ot caloric. _ _/ „ .end lo .JiioniOT/idA TbAdbis jrTIjrw. ,TO2aoiJa ban 3. By alleviating pain and topical derangement by anodynes. mk t + i i k Ji ti v c ' " The heart can be excited by the exhibition ot- 1. Diffusible stimulants; the best is a tumbler of hot camphor . , . . . fdon Jf-blot) amraoi 1 iulep, giving halt an ounce every ten or fifteen minutes, an mfu- . 1 19 an -naaio mmioqmr qiuog do oon&hudgm oar .aanoin sion ot spearmint or peppermint; more active stimulants, as brandy or wine, may be required. Jbrom twenty (20) to thirty . i jiliio osnogib odd ,Ijoifo 1 avob vijooftocr ofi-rnojii jjioxo odd (30) drops ot laudanum, or an equivalent portion of opium or mor- mirozo mlf.il ..iovoi vioJBaimBmii oiqcmOo anol odd aoaiuagB io prune may be given at the same time with the stimulants. 2. Hot drinks when the patient is thirsty-cold drinks should onodumb amHoonn vimi ipaipiimaQo biqdqvd apdrn axing dnoiduq not be allowed even if desired by the patient. In extreme cases, and particularly when the stomach rejects all drinks, brandy may do eftKirnoni o$ob vd ardd him mqiiiarr io ano Up odd IpmlBini oaroi be given pure, dropped on a little sugar, in doses of a teaspoon- r 11 X Ax ' X X I' LV x xT T full- every ten or fifteen minutes, watching its effect on the heart . r ,. , . ^lowatm fon mvz JaomiBoid imiiooqxb and respiration, and withholding it as soon as warmth and general ai odl .inormq inorovBg of daivr uov ii .boDimiaob gf circulation is restored. 14 3. The administration of a warm, stimulating enema for this purpose; a strong infvision of ginger is preferable: if, however, the stomach is so irritable as not to retain any stimulants or medi- cine, or the muscles of the throat paralyzed so that the patient cannot swallow, more stimulating injections must be used, as a tablespoon-full of brandy with a teaspoon-full of laudanum, re- peated from time to time, according to circumstances. 4. With these means should be combined the application of external warmth when the patient is able to sit up; a warm foot bath of water and mustard, continued for 15 or 20 minutes. When not able to be up, hot fomentations, with cloths rung out of hot water, applied as warm as the patient can bare them, and repeated from time to time. Warm mustard cataplasms, hot bricks or billets of wood soaked in hot water, and applied along the body and limbs, bottles of hot water, and where it can be done, the hot air bath. 5. Regulating the temperature of the room. This should be from 70Q to 80^; but fresh air should, if possible, be freely admit- ted, and the covering should be sufficient, but not excessive. 6. Regulating the position of the patient. In severe cases the patient should not, on any consideration, be permitted to rise from a horizontal position. 7. All company and visitors should be excluded, and no person admitted except the necessary attendants. In addition to the above general directions, particular symptoms require some modification of the treatment. If the pain subsides, warmth returns to the surface, and free and general perspiration is produced, the stimulants should be gradually withdrawn; exces- sive sweating would tend to weaken the patient, if too long con- tinued. Anodynes may be given in some other form, but I am accustomed to give a powder composed of camphor, grs. ij., calomel, grs. ij., opium, gr. ss., ipecac, gr. ss., repeated every four hours. Dr. Fisk says, " If we were bold and liberal in the use of any thing, it was calomel; this combined with camphor and ipecac, with opium sufficient to prevent the cathartic effect of the medi- cine, was diligently administered to most until a slight affection of the glands was observed." Mercury is admitted to be the most general stimulant known-stimulating the secretions generally, and is the most efficient agent in preventing and removing local congestions. I have not, however, usually found it necessary to 15 carry it to the extent of producing ptyalism or any perceptable effect on the gums. When the head is prominently affected with severe pain, or delirium, or coma, or convulsions, sinapisms should be applied to the back of the neck and spine, but if the severe symptoms are not promptly relieved, blisters should be substitu- ted. Vomiting which is often a very troublesome symptom, is best relieved by small doses of calomel, comphor and opium, in form of pill, repeated from time to time, with a mustard plaster over the stomach. If the patient is unable to swallow on account of paralysis of the muscles of the throat, we must not abandon him, but endeavor to sustain the system by stimulating and nutritious encmata. If the pain centers in one of the extremities, the best means is the application of a blister in addition to the other gene- boilqqe buc 'loinw foil ni bodnoa boow 'io afollid io The practitioners should be guarded against the administration of cathartics in the early stage of the disease, but if the bowels arc not moved on the second or third day, a mild cathartic of castor oil, or rhubarb and magnesia should be given to remove any irritating matter. If we are successful in removing the local pain and disturbance, restoring general excitement and free and general perspiration, the patient is usually out of danger, and with proper care we may hope for a speedy recovery, If on the other hand, the reaction is imperfect, if the local, disturbance and pain still continue, if the extremities remain cold whilst the heart or chest becomes hot, if the pulse becomes more frequent and the tongue hot and dry, we may be sure the disease has passed into the congestive inflammatory stage. Active stimulants must be abandoned; warm applications should be continued tp the feet if cold, and cold applications to the head if hot, counter-irritation by blisters, mild diaphoretic drinks, mild nourishment, and a persistance in the alterative powders, until some evident effect is produced. If the patient survives for forty-eight hours without material relief, he will probably sink into a typhoid condition, and must be treated accordingly. When the disease is less violent it is sufficient to confine the patient to the bed, give the powder of calomel, camphor and opium for twenty-four hours, with some warm'diaphoretic drink, and counter-irritation, followed by a mild cathartic of rhubarb and magnesia or castor oil. The foregoing article was prepared to be read before the medical society of the county of Oneida, at its annual meeting, July, 1360. APPENDIX. 16 Jt was my d^ign to present the views of others who had had more exp^rjenpq .than myself, rather than any of my own. Subsequent and more ample experience, has not, however, produced any change ip my teWx spotted fever is objectionable as it refers to a symptom of the disease, which conveys no idea of its character, and which though sometimes present is often wanting; while on the other hand it is frequently present in other diseases. The name of " cerebro-spinal meningitis " is still more objectionable in as much as it applies only tp one of the many forms of this protean malady, but carries the idea of an inflammatory affection, thus overlooking the first and most important stage, viz., that of congestion. I have therefore ventured to suggest a new name for the disease, viz: that of congestive fever, which it is believed wi|l apply to all forms of the disease, and at the same time designate its character. It may indeed be questioned whether the term fever can properly be applied to the disease, as in the first stage there is an absence of all those phenomena described as character- izing fever. > r . . . ■ ( .. ] I have subjoined from North's work, on spotted fever, the treatment adopted by several different writers. Dr. Woodward says: ° Having no guide but experiment; bleed- ing, vomiting, purging, sweating and stimulants were all tried; Sweating appeared to give the most relief. The methods to procure it were various, but that which proved the most certain and easy was by the application of external heat with internal stimulants. Fomentation with hot cloths, the application of hot blocks, hot bricks or stones, and a column of steam conveyed into the bed by a funnel wore all tried, but the steam preferred. Laudanum, brandy, wine, essence of peppermint, hot sling, hot herb tea, as pennyroyal, peppermint, rue, saffron and many other kinds of warm teas by themselves, or with spirits, were used according to the habits of the patients and other circumstances. When herb teas would sit on the stomach and produce sweat I thought them preferable to ardent spirits, as not so apt to produce headache and delirium. Sweating produced by any hot application, not essen- tial what, seemed to answer the desired purpose, and after this method was adopted the disease proved much less fatal. Those who died, chiefly went off with the lowness which took place early in the disease, some in five or six hours, but they generally died hid .wb udj no oi W9iv b djivz ton .iiTPWrbvd ots TREATMENT. 17 between twenty-four and forty-eight hours after the attack. If they survived forty-eight hours the disease Assumed the typo of fever and became manageable like othdt febrile' diseases. Some •. T if "t I HP * I died at a later period, but no more than are commonly carried off by Dr. North says: "If I am called to a patient attacked with spotted fever and find him attended with violent pain of the head, drawing back the head, tossing about the limbs', sighing, dis- tress for breath, coldness of the extreme parts, sickness at the stomach, great distress and agony, comatdsd, with an involuntary running of tears, lividness of the lips, or with delirium or mania; with a low or feeble pulse, or perhaps none at all, I conclude that there is no time to be lost; that he is in danger of dying in a few hours, either by syncope or pulmonary congestion, or otherwise. I put the patient to bed after having bat hed his feet in warm water, and then apply a blister to the back of his neck, give tinctura opii, hot brandy sling, heated wine and warm teas. I also apply hot blocks wrapped in cloths near the patient in bed; also bottles of hot water or similar blocks to his feet. In some cases 1 Have given oil of peppermint, essence of peppermint, tiuct. castor, comp., camphor, &c., taking carertp jj^fowd the stomach or excite vomiting. Generally as soon as the patient gets warpa he is relieved; not always, however, until he sweats." Dr. Bestor says, "My practice has been when I found a patient extremely cold, much pained with symptoms of great debility, derangement of intellect, feeble pulse, nausea and retching, with- out any particular evidence of biliousness predominating, the tongue being covered with a white coat, to immediately give, if an adult, from forty to sixty drops of tincture of opium in pennyroyal tea, with half a gill of brandy, apply a blister to the back of the neck and pained extremities, sometimes to the stomach if much pained, hot bricks or stones, or billets of wood taken out of hot water and wrapped in cloths, to be applied to the feet, legs, thighs and sides of the patient. The warm teas to be repeated as the stomach will bear; a glass ot brandy every hour, the tincture \ ■ n p J J of opium to be repeated in dpse^ of twenty drops every two hours, if the stomach can retain it, if not, a teaspoon-full to be given by injection every three or four hours, and continued until sweat breaks out, and the patient is relieved within three or four hours from the attack. I usually give from eight to ten grains of sub- mureate hydrargyri, not with a view to purge on the first day, but 'Art. 7. 18 to act as a stimulus to the system and prepare the bowels to be moved by injection the next day, if the stimulants have had the desired effect, and the excitement of the system is such as to admit of an evacuation.