VESICO-VAGINAL FISTULA; ♦ ITS HISTORY AND TREATMENT. BY D. HAYES 2GNEW, M. D., ABBISTANI LBCiURER ON CLINICAL SURGERY, ANT) DEMONSTRATOR OF ANATOMY IN THE UNIVERSITY OF PENNSYLVANIA; SURGEON TO THE PENNSYLVANIA HOSPITAL; SURGEON TO WILLS OPHTHALMIC HOSPITAL; MEMBER OF THE COLLEGE OP PHYSICIANS AND SURGEONS, ETC., BTC. PHILADELPH I A: Published at the Office of the Medical and Surgical Reporter. 1 8 6 7. Dr. D. S. Lamb, 7 PARK PLACE, V Street, west of Thirteenth. HISTORY AND TREATMENT OF VESICOVAGINAL FISTULA, Mauriceau, in his work, published in 1712) lays down the following aphorism; “L’issue in- voluntaire de Furine caus6e par une fistule qui s’est femme, est ordinairement incurable si elle duze plus si trois mois.” No operation does he propose, but only looks for a cure, when it does occur, as a purely natural or spontaneous result. There is much consoling in the thought that, An most of the diseases and accidents incident to the body, the sufferers are not debarred the so- ciety, sympathy, and entertainment of friends. Such considerations greatly mitigate and sustain, under the severest physical distress. But there is one accident liable to occur in the female—and that, too, in the exercise of the highest function of her nature—which dooms her to isolation and 'seclusion, renders her presence intolerable to friends, and compels her to exist in an atmos- phere repugnant in the highest degree to her own sense. HISTOBY. Hoffman, in 1724, describes the accident, and refers it to the proper cause: “Quando enim librae sub diuturnoribus partus laboribus ad infantis capiti, ad os pubis compressae diu manet fieri deinde solet ut infiamentur, atque in ab- scessum abeant, aliquot denum a partu diebus consummandum; unde fluxus, et stillicidium urinae per vaginam tertio demum, vel quarto die contingit.” It is quite evident, too, the art of the Genevan embraced no means of repairing the accident. Until a very recent period, the unfortunate vic- tim of vesico-vaginal fistula was obliged to con- front her situation under the conviction that her case was absolutely hopeless, and has, in some instances, sought refuge from the mental suffer- ing by self-destruction. One of the grandest triumphs of American surgery—for it is all her own—has been to step in and lead such forth into the light of day, and restore them to the bliss of family and social life. Astruc, physician to the King of France in, 1776, has no notice whatever of the affection in his work. Smellie, in his publication of 1776, although he describes an operation for this form of fistula, had evidently never performed one himself or even witnessed it performed, as he adds, “I wish the operation may not be found impracticable.” Antecedent to the discovery of the forceps, such accidents must have been of very frequent occurrence, although comparatively little is said in medical or surgical works on the subject, as such, were, by common consent, regarded to be beyond the resources of obstetric surgery. Denman alludes to ulceration and sloughing of the vagina after difficult labor, but suggests no remedy. Burns, in his work on midwifery, edited in 1820, by James, describes the lesion, and advises a catheter to be worn for some time, under the conviction nothing else could be done. Hippocrates speaks of a discharge of urine through the vagina sometimes following difficult labors, with some unimportant remarks in re- gard to cleanliness; no hint is anywhere thrown out, leading to an inference that such cases ad- mitted of cure. Without disturbing the repose of ancient medical record, it may not prove unin- teresting to interrogate a few comparatively modern authorities. Conquest, in his Outlines of Midwifery, pub- lished in London in 1820, insists on the propri- ety of attempting a cure by an operation, but does not designate any particular method, nor does he intimate a knowledge of any cures hay- ing been effected. 5 6 James, in his System of Midwifery, of 1813, not only takes notice of this form of fistula, but advises the employment of an elastic catheter, and adds, perhaps it may heal. The same author also speaks of the use of caustic when the open- ing is small, and freshening the edges when it is large, conjoined with the use of the catheter. and while the subject of fistula in general is cussed, this form is not even mentioned. lleister mentions it as incurable. Samuel Cooper, in his Surgical Dictionary, speaks of dilferent kinds of fistula, but does not in any way allude to the one under considera- tion. In 1808, in the Ist volume of his Surgery, some methods of operation for the cure of such fistulas are described, but he evidently doubts their practicability. Ashwell, quite a prominent practitioner and writer in London, in 1828, has no allusion to the subject whatever. William Campbell, of Edinburgh, in 1833, appears to have given unusual attention to the subject. The opening is clearly described, and its most common location, near the neck of the bladder. In his experience, the catheter and recumbent position perseveringly employed has, wThen pronounced by others utterly hopeless, per- manently relieved cases: the phraseology, it will he perceived, will not allow the conclusion that such were cured. Mr. Liston asserts that an operation only makes the patient worse, by converting a small into a large opening, and adds, “There is little hope in a case of any size.” To the same conclusion tend the testimony of Mr. Earle and Mr. Lawrence, both of whom state a successful operation im- practicable. Chelius says the prognosis is always very un- favorable. Miller believes a favorable result by any means improbable. Gooch, in 1831, alludes to a case having got well by a gum-elastic bottle, with a sponge at- tached, being pressed into the vagina and kept opposite the opening. This solitary case of re- ported cure is treated as a very unusual and extraordinary event. Velpeau asserts of all the eases reported as cured, there were few free from doubt. Pirrie has not a word upon the subject. The subject is not introduced by name into the works of Dorset or Gibson. Desault, in his Treatise on the Urinary Or- gans, confines himself simply to the palliative treatment. The cases reported as cured by Lallemande, Phillips of Rheims, and Vidal, in 1834, Vel- peau most positively asserts were not cures. Dupuytren only hoped, by cauterization, to effect something. .Blundell, in his work published in 1834, dis- poses of the subject in a most summary manner by stating, a slough of the vagina may lay open the bladder. Mr. Earle, after thirty operations, succeeded in curing one case; no wonder he pronounced the operation the most difficult or unsatisfactory one in surgery. Ramsbotham, writing as late as 1841, does not treat of the subject. Nelaton, as late as 1854, talked of autoplastic processes and the cautery. These are hut a few of the names which might be introduced. Davis, in 1841, describes the manner in which such an opening is made, with the additional statement, “it is almost a universal fact, that they never do heal.” In 1839, Dr. Hayward, of Boston, succeeded in curing a case by freshening the edges, and approximating them with a thread suture. In 1840, two additional cases were treated, with a similar result, and although twenty operations were performed in attaining these three cures, yet, in a prospective point of view, their value cannot be overestimated. Dewees, in his work on midwifery, makes no mention of it. Churchill, in 1844, speaks of all such open- ings as being perfectly hopeless. Simpson, in his work published in 1865 and ’66, when describing the result of long-continued pressure by the foetal head against the vesico- vaginal septum, speaks of the slough separating and leaving an incurable fistula. In 1847, Dr. Pancoast, Professor of Anatomy in the Jefferson Medical College, reported two cases, cured by a tongue, and groved incision, the wound being adjusted by his silk-thread plas- tic suture. In the same year, Dr. Mettauer, of Virginia, gave to the profession the history of a case successfully treated by vivifying the edges, and uniting the same with leaden threads. Such occasional cures doubtless tended to inspire a hope of the ultimate curability of this disgust- Revbard, in 1856, published a paper on the palliative treatment of this form of fistula, be- lieving the affection incapable of cure. Let us now interrogate a few of the eminent surgeons abroad and at home, and ascertain with what voice they testify on this subject. Ambrose Fare’s great work bears date 1582, 7 granulation. A very singular case occurred in the East London Lying-in Institute, reported in the January number of the French Lancet for 1838, of a woman who, in consequence of a chronic retention of urine, had acquired sufficient dexterity to catheterize herself. From some cause, being without the usual instrument, she extem- porized the catheter with the stem of a clay to- bacco pipe. On one occasion it was broken, a portion remaining in the bladder, and which, in time, not only passed into the vagina, but finally into the uterus, from which it was extracted. ing disease; but it was not, however, until about 1852, when Dr. I. Marion Sims, then of Mont- gomery, Alabama, gave to the profession the fruit of his labor and observation, by which this oper- ation was removed from the category of proba- bilities, and crowned with a success which com- pared favorably with any of the established op- erations in surgery. For this he has placed the civilized world under a debt of gratitude. Among the causes inducing this lesion maj be enumerated: Causes. Third. Carcinomatous and other forms of ul- ceration.—Almost every work treating of the dis- eases of the female genitalia, furnish examples of malignant growths, involving the uterus, and gradually invading, by destructive ulceration, the vagina and rectum, until they become converted into a common cavity. Phsegedenic chancre may produce a similar result. Two cases of this na- ture came under my own observation in the wards of the Philadelphia Hospital, rendering the poor, unfortunate outcasts, objects of the pro- foundest commiseration. First. The. Pessary.—When this instrument is out of proportion, and fitting badly, or corroded, or encrusted with saline matters, it may induce ulceration of the vagino-vesical septum. Profs. Beirards and Liseranc each relate a case of the bladder and rectum both being opened, by a pes- sary; one of the patients died of peritonitis [Jour. Nouv. Held. de Med., t. 1, page 263.) A case of Dupuytren, in the Hotel Dieu, is recorded in the Diet, des Sciences Med., t. vii., p. 47, of a young country woman, whose rectum, vagina, and bladder freely communicated in consequence of wearing a badly adapted instrument; both of these were produced by stem pessaries. A case of this kind is also cited by Desqrmeaux, a French physician. In most of them, doubtless, the ulceration was brought about by saline de- posit on the exterior of the instrument, the angu- larities of which matter would very soon produce destruction of tissue. Other cases might be in- troduced in illustration of the same point. In earlier times it is probable such accidents were common, when a great variety of extraordinary materials were employed, not only for mechani- cal support, hut as means of introducing remedial agents into the organs of generation; at present, improvements in the form and substance of me- chanical supports will not be likely to furnish us a case illustrative of the condition under consid- eration. Fourth. Wounds of the Vagina-vesteal wall in the legitimate and illegitimate use of instruments. Enderthe first maybe enumerated the careless employment of the obstetrical vectis or lever, bruising or lacerating the tissues by long-con- tinued efforts to modify a foetal position, or the slipping of a perforator in cases of craniotomy. The forceps has come in for a large share of ani- madversion, but they have little agency in pro- ducing such an accident; their earlier, and more frequent employment, particularly in educated hands, would have prevented many which have occurred. Under the second head may be ad- duced the violence committed by those ignorant scoundrels who flourish in every great city in their criminal attempts to procure abortion. Fifth. Pressure of the foetal head.—This, above all others, is the most common cause of vesico-vaginal fistula. It is probably not going too far to say 90 per cent, of such occurrences are due to the prolonged pressure of the foetal head. The testimony of almost all authors harmonizes in this particular. It was so regarded by Mau- riceau; yet singular enough, he was greatly opposed to the use of instruments, whereby a tedious labor might be brought to a close. This prejudice it is said was due to the failure of Chamberlayne to deliver a woman in Paris after a public boast. Not being aware of the existence of a deformed pelvis he had torn the vagina and uterus in several places in his ineffectual efforts to extract the child with the forceps of which he Second. Foreign substances in the bladder.— Under this head may be mentioned vesical-cal- culi, examples of which are by no means rare. Fa'bricius Hildanus relates an instance of this nature. Sir Benjamin Brodie another, in which the stone made its way into the vagina by ulcer- ation ; and a third is given by Sir Astley Cooper. Dr. Dunlap, of Norristown, in this State, exhib- ited to me a calculus as large as a hen’s egg, which he extracted from th’e vagina of a female, who had long suffered from the disease, and which had perforated the vesico-vaginal septum, A most interesting fact connected with this case, was the perfect restoration of the parts subsequently by 8 was the inventor. Denman attributed the lesion to long-continued compression of the soft parts. Davis expressly declares that it does not result from the use of instruments, but delayed labor. Dr. Simpson stops to fortify a similar opinion by stating “these abnormal openings, if produced by instruments, should appear at once, while it is known they only occur several days after their use.” Smellie, Colombat, and Churchill, all describe the fistula to protracted pressure during labor, and an opinion of similar import is enter- tained by Professors Hodge and Meigs. Doctors Sims and Boseman, whose opportunities for ac- quiring accurate information on this subject have been extensive, testify to the same fact, and ex- cept in a single case my own observation accords with these gentlemen. Third. At the has-fond; the opening involving: the inferior fundus of the bladder. Fourth. Vesico-utero-vaginal; where the open- ing communicates with the bladder, vagina, and cervix, or body of the uterus. Fifth, Fortunately quite rare where the entire vesico-vaginal wall is destroyed, and it may be the urethro-vaginal also. The relative frequency of these varieties, as they have come under my own notice, is as fol- lows: First, at the vesical triangle; second, at the bas-fond; third, in the urethro-vaginal sep- tum; fourth, the utero-vesical; and last, the one attended with a destruction which includes the first four classes. This, I think, accords with the experience of most observers. Dr. Boseman, I believe, states, according to his observation, the vesico-utero-vaginal is the most common. I have never but in a single instance seen an example of this kind. If the foregoing statements be correct, what is the modus—the manner in which the lesion takes place? The head in passing through the pelvic cavity presses the anterior wall of the vagina toward and against the posterior face of the pubic bones. If in consequence of failure of the uterine expulsive efforts, or a dispropor- tion between the pelvis and the head, or a want of accord between the diameters of the two, the head long remains thus engaged, the vitality of the soft parts so compressed and bruised will be destroyed, either by the formation of a slough or by inflammation and ulceration. It is asserted by some that a fold of the vagina is caught and pressed against the pelvic bones until its death is insured; but it does not seem probable any such folds would exist when the canal is so greatly distended. The period when the opening occurs varies in different cases; in some as early as the fourth or fifth day, and in others the event may be prolonged—as in one which came under my own observation (case 4)—until the twenty-first day after confinement. When the parts are so injured as to induce ulcerative inflammation, a longer time is required to penetrate the vagino- vesical wall than where they are killed outright, and drop out as a slough. These fistules may be transverse, oblique, or longitudinal; determined, it may be presumed, in a great degree by the particular part of the foetal head impinging, or the exact manner in which the vaginal parieties may be caught. The trans- verse variety has most frequently come under my own notice. Direction. The configuration or form of such openings may be oval, round, linear, angular, and eliptical; the last most common. A careful study of the muscular component of the vagina will explain this. Its fasciculi are disposed longitudinally and circular; the former the most numerous and dis- tinct; and of these, those on the lateral parieties are so associated with the levatores ani that they contract less when divided than those occupying an intermediate position, and hence the ovidal or eliptical form of most fistula. The dimensions of the opening also vary from an aperture so small as barely to admit the introduction of an ordinary probe, to one through, which might be passed a good-sized egg. So far as the patient’s comfort is concerned, the small opening is quite as bad as the large one; in either case the urine will be constantly passing the vagina. Form, Size, and Condition. Classification. These fistula! may occur at any point from the middle of the urethra to the termination above of the anterior wall of the vagina, but practi- cally the classification of Sims or that of Dr. Boseman, the two differing very little, answers every purpose. The condition of the borders of the fistula—like its size and form—differ much. Sometimes they are, especially the upper one, thin, inverted, quite pale and smooth; in other instances thick, soft, spongy and vascular; and again of almost carti- lagenous consistence, inextensible and sparsely supplied with blood vessels. The mucous mem- brane of the bladder often projects through the opening, forming a red, erectile-looking tumor, First. Urethro-vaginal; the opening being be- tween the urethra and vagina. Second. In the trigone vesicate; the opening being situated at the cervix of the bladder. 9 Dr. Gross gives a remarkable ease—in his work on the urinary organs—of the entire bladder es- caping through such a fistulous orifice into the vagina. The condition of the edges as to thick- ness, density, and vascularity, is a matter of great practical moment in the cure of disease. but the one on the side answers every end, and Is more in consonance with her feelings of modesty and propriety. With the aid of the speculum no doubt need exist; without it no examination is complete. I have been called to cases said to be vagino-vesical fistula;, but which on occular in- spection proved to be incontinence from defect in the muscular endowments of the vesical cervix allowing the urine to find its way back into the vagina after escaping passively from the urethra. Diagnosis. It is not usually a difficult matter to ascertain the existence of this affection. If inquiry be made as to the state of the bladder immediately succeeding the labor, the patient or her attendant will state that for two or three days there was an inability to evacuate its contents, with some pain or uneasiness, requiring perhaps the use of the catheter; after this a stillicidium of urine through the urethra; or this last condition may have been present from the first. At some period, however, varying from five to twenty days from the labour, the incontinence is complete, the urine escaping entirely from the vagina. The patient sometimes describes this state as being preceded by a sense of something giving away. The labile, inner surface of the thighs, perinmum, and the buttocks being constantly bathed in the secretion become red, inflamed and covered with a crop of pustules, which sometimes form ulcers of considerable depth. The genitalia and surface of the vagina frequently become encrusted with a saline deposi- tion (urates)', and a strong urinous odor is emitted from her person and clothing. These may be re- garded as the rational signs of the disease. Al- though they do not in themselves establish or justify the conclusion that a fistula exists, they form a strong presumptive proof of the fact. Only upon a physical exploration of the parts can we ascertain with certainty the accident. With this view let the patient be placed in bed, on her side, with the limbs well drawn up, and the hips on the edge of the same, before the win- dow, with a good light. Introduce the duck bill speculum into the vagina, and draw the perineum well back toward the sacrum until the entrance of the air distends the vaginal cavity. If the lesion exists it will most likely be at once detected, un- less it should be so small as to escape observation. That it be not thus overlooked, a pocket-case probe should be introduced into any suspicious pockets or depressions, and moved carefully about until their nature and extent are determined. Where the aperture is so sfhall as not to be readily found, it has been advised to inject through the urethra into the bladder some colored liquid, dis- tending its walls, and carefully noting if any can be discovered passing into the vagina. Some prefer having the patient on her elbows and knees, others on the back in making the examination, Complications. tinder this head may be enumerated stricture of the vagina, recto-vaginal fistula, obliteration of the urethra, and malignant disease of the uterus or rectum. Treatment. The treatment of vesico-vaginal fistula includes the preparation of the patient, the operation, and subsequent management. Preparation. No woman can be in the best condition to undergo an operation for her cure, until after the lapse of at least eight or ten weeks from her confinement. I have operated as early as the fifth week, and with complete success, but, nevertheless, do not think so early a date should be fixed as a rule in practice. It requires at least two months before the system has completely recovered from the perturbating influences of the parturient act, and her secretions duly established. The moral and physical suffering induced by the existence of the fistula tend to put the woman out of health. If we find her pale, feeble, with loss of appetite, and harassed by a train of ner- vous symptoms, it may require several months of preparation; during which time a carefully regu- lated nutritious diet will be demanded, fresh air, attention to the intestinal and other secretions, conjoined with the use of tonics, such as the pre- parations of iron or infusions of the bitter vegeta- ble class. It is certain, no one familiar with the treatment of this form of fistula, will be rash enough to subject his patient to the inconveni- ence of such an operation, before attending to these preliminary measures. There is no operation in surgery which de- pends so much for its success on healthy consti- tutional conditions as the one under consideration, nor must we overlook the local treatment. All inflammation must have subsided, the connective tissue component of the parts must be well ma- tured, and sufficiently dense to withstand the traction of the sutures, the edges of the opening should have considerable thickness and a good supply of bloodvessels. All this will be favored by due attention to cleanliness, injecting tepid or cold water, with the addition of a little palm 10 soap, or a decoction of*oak bark into the vagina every day. Should the edges continue pale and thin, they must he subjected to a special treat- ment, with a view to make them more volumi- nous. This is best accomplished by making a few shallow' incisions parallel to their long diam- eters, and rubbing into each a little nitrate of sil- ver. The caustic should be used about every third day. In the course of a few weeks, the requisite change will have taken place. The saline mat- ters, which so commonly encrust the margins of the fistula and other parts of the genitalia, pro- ducing much uneasiness, may be counteracted by the internal administration of nitro-muriatic acid, as a good tonic. The excoriation due to the uri- nous stillicidium, is best relieved either by an ointment of the precipitated carbonate of zinc, or by a mixture of the black wash and glycerine. Attention must also be given to her catamenial pe- riod, three or four days after its accomplishment being the most fitting time for the operation. If done during the latter half of the month, the irritation of the parts, together with the prolonged etherization, are prone to produce premature men- struation. The day previous to the operation, a gentle cathartic should be administered, after the action of which, one grain and a half of opium, in pill, should be given to quiet all intestinal irri- tation. is effected by either graduated bougies or sponge tents. I have practised each method, and am confident the last is the most certain and least painful. This is divided into the palliative and radical. If, in consequence of extensive destruction of tis- sue, or the presence of malignant disease, an oper- ation is contra-indicated, we may resort to some means to palliate the distressing situation of the patient. These chiefly point to the collection of the urine so as to defend her person against ex- coriation, and offensive emenations. There is no task so difficult, and unsatisfactory as this. Many recepticles, and obturators, and other con- trivances have been devised; such as a bag of gum elastic worn partly within, and partly with- out the vagina, styled by Colo meat the “ iron d' enfer” of Feburier; or a gum bottle with a sponge on its anterior face, introduced into the canal; or tampons of fine linen, or soft sponge so adjusted as to occlude the opening. Of all these devices the metallic shield of Prof. Meigs answers the best purpose, yet it must be confessed, all are but sorry contrivances, and will be soon aban- doned. A rigid attention to cleanliness, by fre- quent ablutions, and the use of an inter-femoral napkin or diaper, will perhaps give the most sat- isfaction. Fabricius Hibdanus, as related by Colombat, furnishes an instance of a case which was cured, after eight months, by vaginal injec- tions, consisting of barley-water, and the mucil- age of quince seeds; the following passage, in his quaint style, narrates the event, “Ilia autem continue usa medicamentis (ut dixi) conglutinan- tibus, et per intervalla etiam purgantibus, intra menses octo, non sine admiratione omnium eorum quibus res cognita plane curata fuit, adeo nunc Dei optimi maxima gratia ne guttula quidem urinse involuntarise affluat, sed a vesiefi colligatur, retineatur et excernatur non aliter ac si antea nunquam male affecta fuisset.” Treatment. Should the fistule be the result of carcinoma- tous ulceration, any operation will be futile, as everything tends to a fatal termination. When it co-exists with a recto-vaginal opening, the escape of purulent matter into the vagina will be unfavorable to healing; yet, if the peristaltic movements can be sufficiently controlled by opium or some of its preparations, there is no reason why the vagino-vesical fistula should not be closed, before undertaking that, between the vagina and intestine. The complication most commonly met with is stricture of the vagina, and, as the opening is usually above it, nothing can be done for its re- lief until the dimensions of the canal are properly restored. Three methods may be employed for this purpose. First. Incisions of the stricture through the mucous and submucous tissues, fol- lowed by dilatation. Second. A submucous di- vision of the contracted bands, and subsequent dilatation; and third, dilatation alone. Choose which we may, there is a strong tendency in the stricture to return. If incision be selected, the reformed parts have the same vicious tendency to contract, and although this is true of dilatation, it is less so than either of the others, and should be selected as best adapted for our purpose. It Radical treatment.—lt was only about the be- ginning of the present century any attempts for the cure of this distressing malady were thought of, and only within the last fifteen years that any encouraging results have been attained. At pre- sent we approach the management of a case of vesico-vaginal fistula with the same degree of con- fidence as that of stone, or hydrocele. The his- tory of the various methods practised for its cure— although most of them have passed into history— will be presented, as they furnish the most re- markable example of untiring, undismayed perse- verance in the face of the most unpromising re- sults, and of a fertility of professional resource to 11 be found in no other department of medicine. These methods may he arranged under the follow- ing heads: ATo., 1824. Colombat speaks favorably of this plan, provided the edges be first cauterized. It is probable any such cases reported as cured, recov- ered, not from the but from the perse- vering use of the catheter. The could exert no influence whatever in pressing together the sides of the fistula, but just the reverse, by unfolding the rugae or plications of the canal by distension. Let any one notice how a fistule gaps when the speculum is introduced, and the canal distended with air, and then, in withdrawing, how the sides collapse, and the demonstration will be clear. Ist. By the catheter. 2d. By the catheter, conjoined with the lam- poon. 3d. By cauterization 4th. By the uniting apparatus. sth. By galvanism. 6th. By transplantation. 7th. By the suture. First. By the Catheter.—-It is important to as- certain, at the earliest moment, the existence of a fistula, as a little well-timed attention may pro- cure a cure without an operation. There are cases in which there exists a strong tendency to to spontaneous cure, and advantage should be taken of this, and a catheter placed at once in the bladder, and worn for three or four weeks, the patient being confined to the recumbent position, and due attention to cleanliness observed. A number of such cases terminating successfully have been placed on record, by Fabricxus Hilda- nus, Blundell, Ryan, Sedillot, Campbell, of Edinburgh, Nelaton, and others; and I doubt not similar ones may be recalled by many prac- titioners extensively engaged in obstetric medi- cine. Third. Cauterization.-—Of this, Colombat said, “It is the best method we can oppose to vesico- vaginal fistula.” The agents employed were either the nitrate of silver, or the actual cautery. The former was conveyed to the fistula by fixing a stick in a porte-crayon, and conducting it to the opening through a fenestrated speculum in- troduced into the vagina, and repeated every four or five days, followed by emollient injections to relieve pain. After the edges begin to assume a swollen, or raw appearance, a catheter, according to Colombat, should be placed in the bladder. A few successful cases by this mode of treatment have been reported by Dupuytren, Delpech. McDowell, of Kentucky, Liston, Colles, and Ferrall, When the cautery was used, a bean- shaped stillet, heated to a white heat, was applied to the opening, a fenestrum shielding the vagina being first introduced—and the parts lightly touched so as to induce a superficial slough. The advocates for caustics have been Chelius, Yacca, Berlinghien, Czeekiersky, Ehrman, Monteggia, Guthrie, and Colombat ; for the hot iron, Dupuy- tren, Delpech, Bellini, McDowell, Liston, Blasius, and Dieffenbach. The caustic treat- ment was somewhat modified by Lallemand, principally, who conjoined with it a uniting ap- paratus. This surgeon was so particular as to take an accurate cast of the fistule with a very plastic wax. After the edges were made suffi- ciently alive by the caustic, he adjusted his in- strument, one portion of which acted as catheter, and through its openings hooks were made to protrude, penetrating the posterior lip of the fis- tula on its vesical surface. A roll of lint, or charpie, was next placed against the under surface of the urethra, and pressed upward toward the vagina by a moveable plate connected to the an- terior extremity of the catheter, the object being to press the lower lip of the fistula toward the other or upper lip impaled by the hooks. Dupu- tren attempted the same thing by a peculiarly constructed catheter. Langenbeck very properly Second. Catheter conjoined with the Tampon. This is usually described as the method of De- sault, although it more properly belongs to Boyer—the name of the former having doubtless become connected with it in consequence of the truss-like apparatus which he devised to sustain and retain the catheter. A large-sized elastic catheter is introduced into the bladder, and its end slipped through an open- ing in a curved rod, one end of which is to be opposite the urinary meatus, and the other se- cured to an oval plate which rests on the pubes, and is in turn securely attached to a truss-spring surrrounding the pelvis. This controls the cathe- ter, by which means the urine is removed as rapidly as deposited. The margins of the fistula were next pressed toward each other by a round tampon, or plug, made of fine linen filled with lint, well oiled, and pressed into the vagina. It does not appear, of the many cases thus treated by Boyer, more than a single one recovered. With a very slight modification of the vaginal plug, others—as Baines, Guthrie, Young, and Barnes—have reported cures, the treatment con- tinuing from six to twelve months. Those, cu- rious to peruse these cases, will find most of them in the Med. Chir. Trans., Vol vi., page 582; and the Edinburgh Med. and Surg. Journal, April 12 pronounces such devices as complicated, and de- void of practical value. was kept constantly in the bladder during the treatment. In one case the growth of hair, the follicles of which were in the flap, induced a vagi- nitis, and also interfered with the execution of the conjugal act.' In one case the material to form this fleshly obturator was taken from the buttock and thigh, and proved altogether success- ful in effecting a permanent cure. The results of four cases reported, furnish us with one cure, two failures, and one death. Where a large part of the vaginal-vesical septum has been destroyed, the operation of Jobert might answer a valuable purpose. Fourth. The Uniting Method.—Laugier, in order to bring the edges together, invented a pair of claw-forceps, the blades of which could be in- troduced separately, and after being implanted on opposite sides of the fistule, secured together, by which the coaptation was effected. Quite re- cently, an instrument, acting on the same princi- ple, has been invented by Dr. Betancourt, while pursuing his studies in the University of Pennsyl- vania. Fig. 1. Seventh. By Suture. The introduction of the suture marks an important epoch in the history of vaginal fistulas. It was a step in the right di- rection. The credit of its introduction is due to Roonhtjysen, a distinguished obstetrician at Ams- terdam, who proposed its use in 1663. It was violently opposed long after by the celebrated Petit, who asserted that incising and introducing a thread in parts so situated was a task almost incapable of execution. The operation of Roonhuysen consisted in fresh- ening the edges by means of a knife, scissors, or cutting forceps, operating through a speculum, then pushing across the opening needles, formed from the quill of the swan, and binding the parts together by winding about these novel pins, thread as we apply the twisted suture. Lews- inski, long after, in 1802 proposed the suture. It formed the subject of a thesis before the Faculty of Medicine in Paris. His instrument for placing the ligature was a catheter, carrying a needle which had a spring attached, and bearing a thread. This instrument was passed into the bladder, the spring pushed forward, making the needle to pierce the posterior wall, afterward the anterior wall, and securing by a serre-noeud. Mg. 1 is two light metallic plates connected by a hinge ; their margins are scalloped, and support sharp hooks, designed to sieze the margins of the fistula. In one plate are two eyes, and in the other, two moveable posts with shoulders, which are intended to pass through the eyes and hold the plates together. These processes, unlike the others, act on the vaginal surface of the opening. As to their value, it may bo said of all of them, what Langenbeck pronounced of Lallemand’s mode, “ they are theo- retical, and devoid of practical value.” Lallemand, as far as I can ascertain, never re ported more than a single case of cure, and even this Velpeau declares proved a failure. Laguier confesses he had not succeeded in a single instance with his uniting forceps. Yolter recommended after pairing the edges to coaptate by the interrupted suture. To exe- cute this he used curved needles, threaded with waxed silk, and passed them at short intervals through the margins of the fistulas, securing each by tying in a knot. Fifth. Galvanism.—The attempt to cure this malady by galvanism, is due to Mr. Marshall, of the University College, London. The impression was to be made by bringing the poles of a battery in contact with the sides of the opening, and was only another phase of the cautery. It only serves to demonstrate the straits into which men are thrown when they resort to such chimerical expe- dients. Xagele’s method consisted in removing the circumference of the opening with a knife or scissors, the edge of which was guarded by a shield, moveable at pleasure; then introducing the thread sutures by a peculiar needle, one end of which was supported on a ring, through which the finger could be slipped, and near to the other extremity or the point was an eye for the thread. The point was guarded by the finger while being carried to the fistulas, and after the sutures were passed the parts were drawn to- Sixth. Transplantation.—A very ingenious operation was devised and executed by Jobert; it was by transplantation of tissue. The circumfer- ence of the fistula being drawn down, was fresh- ened, a flap was raised from the inner surface of the labium, and being turned into the opening, was secured by a number of stitches; a catheter gether, by twisting their ends together and allow- ing them to hang out of the vagina. Not the least important part of his plan was the use of the silver catheter; but singular enough its utility was destroyed in a great measure by the attach- ment of a stop-cock, only allowing the urine to flow at particular times. The same authority proposed the use of gilt or silver pins, and around them silk threads. He employed likewise the glovers suture: and for stitching a watch-spring, with a needle point, and concealed in a la forest catheter. retained by twisting the wires. To keep the bladder empty an elastic catheter was worn, and the patient requested to lie on the b) east. It is worthy of notice here that this surgeon, in execut- ing his operation placed, his patient on her elbows and knees. Kilian separated the walls of the vagina with blunt hooks; used a silver catheter, curved, simi- lar to the male instrument, to bring the fistula forward for incising; and with curved needles, directed by a Wutzer needle-holder, passed the requisite number of threads, which were secured by Desault’s knot tightener. Flamant manifested most concern about par- ing the edges of the fistulas, to accomplish which he advised the use of a knife guarded at the point to protect the adjoining parts. The atten- tion of Le Roy was most directed to the same subject; and hence we find him proposing differ- ent forms of cutting instruments, and also a fenestrated speculum, with hooks to unite the sides, as a substitute for the suture. Blasius advised a grooved suture. The mar- gins of the fistula were fashioned with a sharp- pointed knife, as follows: Taking hold of one side with a hook or forceps, It was split longitudinally, or parallel with the long axis of the opening; then seizing the other and everting it, the knife was applied to its surfaces in such a manner as to give it a cuneiform or wedge-shaped form; nee- dles armed with thread sutures were next passed, drawing the wedge-shaped side into the gutter or slit of the opposite, constituting a tongue and groove (as he calls it) adjustment. He claims for this a more extended apposition or contact of raw surfaces. freshened the edges with a pair of curved scissors; deposited wax threads by means of curved needles, supported on a needle-holder, and made them secure by introducing the ends through a rosary of small wooden balls or beads, and making them fast by tying over a little cross- piece. The same surgeon used the glovers suture. Lewzisky’s operation consisted in inserting the stitches by means of a canula, traversed by a watch-spring, supporting a needle bearing a thread. This instrument was carried into the bladder, and the needle made to project from the canula, puncturing the septum from the vesico toward the vaginal side. By repeating this pro- cess above and below the opening, the ends of the sutures were all brought into the vagina, and se- cured on that side. This operation is similar in ■most respects to that of Nrgle, and includes the entire thickness of the vesico-vaginal wall. Luke employed a bivalve speculum to expose the parts, angular knives to incise the borders of the fistula, hooks to draw it down, and curved needles to deposit the sutures. Malagodi used a leather thimble, which he placed on the left index finger, and hooking it under the margins of the openings pared the edges when thus stretched, the approximation being made by silk threads introduced by curved needles, manipulated in the grasp of a needle- holder. To prevent urinary infiltration a ca- theter was worn in the bladder, and the vagina stuffed with lint or chapie. Colombat furnishes us with an operation much more remarkable for its ingenuity than utility. The chief novelty of his method consists in using a spiral needle, not unlike a corkscrew, (Fig. 2.) Ehrman recommended scarifying or cauteriz- ing the edges, and then bringing them together with sutures, passed by curved needles, managed with a porte-aiguille. When he used cauteriza- tion a tube was inserted into the vagina, and through it a brush, dipped in a mineral acid, was carried up to the fistulous opening. The specu- lum he employed was a tri-valve, and his sutures were inserted by curved needles. Fig. 2. Colombat Needle. having a steel-point, with an eye for the thread. At the other extremity, where it combines with the handle, there is a second eye, through which the ends of the thread are passed, after being wound about the spiral of the instrument. After vivifying the edges with a pair of cutting forceps, the needle is made, by a rotatory movement, to pierce one side of the fistula; then the other, Gosset, surgeon at one time to Newgate, Lon- don, operated successfully in 1884 on a case by the following method: The edges were carefully pared; metallic threads, well gilded, were intro- duced by curved needles, passed with a needle- holder, and the sides brought together and so 14 and so on, just as one would bore a gimlet, until its entire length was traversed, when by reversed turns it was removed, leaving the thread in its track, as represented in Figs. 3 and 4. This is a Dieffenbach, to expose the fistula, used a hi valve speculum; seized the margins with a hook or long forceps while they were being pared, and united them with the interrupted suture. The position which he preferred having the patient for the operation, was on the back, and the cathe- ter was used continuously to drain the bladder. In his hands, the results were most discouraging. On one woman he operated eighteen times, and then failed to effect a cure. So great was his interest in the subject, that he had gathered wards full of women afflicted with this malady, from all parts of the country, but, as he states himself, making very few cures. Fig. 8. Fig. 4. Glover’s suture. The ends of his threads were twisted together and secured with sealing-wax. Dieffenbach very facetiously remarks, this in- strument only needs a clockwork attachment to go right. Beaumont, after paring the edges, introduced double threads; through the loops on one side was inserted a cylinder of some round substance parallel with the border of the opening, and along the other side a second, over which the free ends of the sutures were tied, forming a quilled suture. Deybers employed a wooden catheter, intro- duced through the urethra, to control the edges of the opening, while being subjected to the knife. The stitching he effected by means of a curved tube enclosing an eyed stilet for the thread, and which was controlled by a spring protruding or withdrawing the point at pleasure. The sutures he used were either silk or lead-wire. Thus far the fistula under consideration has proved more than a match for the skill of the ablest of the old world, and now we turn to American surgery to have our hopes revived and faith strengthened. In 1839, Dr. George Hayward, of Boston, re- ported a case, (see p. 7,) which he had succeeded in curing. His patient was a lady, aged 34 years, in excellent health, and who had been delivered 15 years previous with instruments after, being in labour three days, during which time no urine had been drawn from the bladder. A slough was the consequence, opening a communication be- tween the vagina and bladder. Attempts had been made with the catheter, and also by cauteri- zation to close this fistula, but without success. Dr. Hayward operated on the 10th of May. The patient was placed on the edge of the table, upon her back, very much as in the position for lithoto- my ; the parts well dilated, (he does not state how); a large bougie passed into the bladder, and carried back to the fistula, by which he was able to bring it into view. Thus fixed, an incision was made round the opening with a scalpel, and after the bleeding ceased, the membrane of the vagina was dissected away from the bladder to the extent of three lines. Three silk threads were next intro- duced by curved needles through its sides, drawn together and knotted firmly down; a short silver catheter, prepared for the purpose, was placed in the bladder, and the patient put to bed. In five days she was examined, the stitches cut away, and the parts found to be solidly united. In 1851, Dr. Hayward published an account of eight additional cases, making in all nine cases, three Roux fixed the edges with a long pair of for- ceps while they were being incised; passed across them silver pins, and drew the wound to- gether by winding about them threads similar to our twisted suture. Wuther incised the fistula with either curved scissors or a sickle-shaped knife, fixing it first with a hook, and used sometimes long-stemmed needles, sometimes short curved ones passed with a needle-holder like that of Roux’s; and at other times insert-pins, surrounded with threads to bind the edges together. His patients during the operation kneeled, or were kept on their hands and knees, and the vagina exposed by introduc- ing a hook speculum—really an instrument simi- lar to the Sims’ speculum. In order to defend the wound against the action of the urine, and keep the bladder empty, the organ was opened above the pubes, a catheter introduced, and the patient kept upon her belly, buckled to a leather cushion in which a hole was cut out. On the sixth day, his ligatures were removed, injections of cold water having been thrown into the bladder, through the catheter, and the vagina, through an oesophagus tube, every half-hour. In eighteen operations, three cases were reported cured; a success pronounced extraordinary, and greater than than that of any other surgeon. 15 of whom had been cured after twenty opera- tions. There can be little doubt that Dr. Sims reached this important combination of improvements, quite independent, perhaps, of foreign aid ; yet, by reference to the historical enumeration of methods which I have detailed, it will be found almost all have been conceived and executed by predecessors. In illustration of this, let them be examined in detail. In these cases of Dr. Hayward there was nothing new, unless it was the peculiar catheter; it had often been practised before, but in his hands was crowned with a success, calculated to inspire confidence in the curability of the affection. In 1847, Prof. Joseph Pancoast succeeded in effecting two cures. The posterior or upper lip of the fistula was exposed by a Charriere speculum, and split one half inch deep in a longitudinal di- rection ; with a pair of scissors and bistoury, the lower lip was next pared into a wedge-shaped form, and this tongue of raw tissue, drawn into the grove in the upper border, by what he called his plastic suture. The bladder was kept empty by a gum elastic catheter, and after the second day, injections of zinc were thrown into the vagina to give tone to the parts. On the fourth day a solution of the nitrate of silver was applied over the line of apposition, to favor union by granulation, where that by the first intention failed. In this method, we have a repetition of the plan of Blasius. First, the position. This was recommended and practiced both by Chelius and Walter; the later of whom employed a blunt hook for open- ing the vagina, which executed in a good mea- sure, the office of the duck-bill speculum. Second, the suture apparatus. In 1834, Gos- set, of London, emplo}md the metallic thread; Devber, also; the former gilded wire; the latter lead. Beaumont carried his sutures around lit- tle cylinders, placed one on the other side of the fistula; thus resembling the clamps. Third, the self-retaining catheter. Dr. Met- taper employed, in his case, a short instrument which was worn in the bladder during the cure, so that really all these novelties, have, at some time or other, engaged the notice of surgeons, during the long years of experiment and device which have marked the history of vaginal fistula. Still, however, the undivided honor of combining, modifying, and utilizing, all belongs, and only belongs to Dr. Sims. In the same year, Dr. John P. Mettauer, pub- lished in the American Journal of Medical Sciences for July, the history of a fistula, which he cured by inserting leaden sutures, after par- ing its circumference. The bowels were kept closed for eight days, and the stitches allowed to remain thirteen days, during which time a short catheter was worn in the bladder. The metalic thread used by the operator in this instance, was undoubtedly the procuring cause of so fortu- nate a result. Just at this point commence the most important facts in the history of our subject. Position of the Patient. A table is selected, 2j by 4 feet, covered with folded comfortables; on this the patient is placed, resting on her elbows and knees, the latter separated six or eight inches, the pelvis being elevated, and the shoulders depressed. An assistant on either side placing a hand in the fold between the nates, the fingers extending quite to the greater labite, simultan- eously draw them asunder. The viscera gravita- ting toward the thorax, and the air rushing into the vagina on the separation of the walls of the vulva, distend the canal so as to offer a very com- plete interior view. To increase its capacity for a more thorough exploration, the Sims speculum (Fig. 5) is next introduced, and drawn back to- Dr. Sims’ Operations. In 1852, Dr. J. Marion Sims, of Alabama, solved the whole difficulty, and placed this vexed and perplexed operation, on a solid and substan- tial foundation. The discoveries which he ad- vanced as peculiary his own, were the following: Ist. A method by which the vagina could be thoroughly explored, its capacity greatly in- creased, and the fistula made readily accessible. 2d. The introduction of a suture, which would remain a long time, without inducing either irri- tation or ulceration. Fig. 5. 3d. A mode of keeping the bladder drained of the urine. The first was accomplished by placing the patient on the knees and elbows, the hips being elevated, and using a speculum, which from its form is called the duck-bill speculum. The second, by substituting the ordinary thread with a metallic (silver) one, aided by leaden clamps; and the thin, by a self-retaining catheter. Vaginal speculum similar to Sims’—Bozerman’s pattern. 16 ward the sacrum by one of the assistants. (Fig. 6.) along, sharp-pointed bistoury is applied (Fig 8) vesical mucous membrane concealed the margin of the fistula, interfering with its proper manage- ment, a soft sponge should be passed through the opening into the bladder, and allowed to re- main until the stitches are ready for adjusting. To remove the blood from the parts during the freshening of the parts. The lining membrane of the bladder he does not disturb, unless it pro- Fig. 6. Fig. 8. Exhibits the speculum in situ, with the relative position of the organs. If the illumination is not sufficient, a mirror (Fig. 7) may he used to reflect the light into the canal. Fig. 7. Mirror to throw the sunlight into the vagina. Paring the Fistula. For this purpose, a small sharp hook, or tenaculum, is passed iuto the cir- cumference of the fistula, and while thus brought into proper position, and made sufficiently tense Tenaculum fastened into the fistula, and the bistoury applied to its circumference. 17 trades through the opening in excess. When the fistula was very small he hooked the tenaculum through both sides, and raising it up, cut out a circular portion with the bistoury. During the operation, little mops (Fig. 9) should be on hand. These are readily made by securing small bits of sponge to whalebone or rods of wood. across the wound, and bringing it out half an inch above the raw margin of the opposite side; taking care not to include the mucous membrane of the bladder. As the needle passes through the distal side, the tissues will require support, that they press not away from the instrument; and thus counter-pressure is supplied by a blunt hook behind the needle (Fig. 11.) Application of the Clamp Suture. This may may be divided into three stages: the introduc- tion of the silver wires; the attachment of the clamps; and the approximation of the wound, with the securing of the apparatus. Fig. 11 First. Introduction of the Sutures. In the ex- ecution of this he passed a silk thread through the eye of along, awl-shaped needle (Fig. 10), and Fie. 9, Fig. 10. The blunt hoolv between the needle and tissue to favor its passage. A sponge mop. Needle for passing sutures. entering it half an inch from the freshened edge of the opening, carried it downward, and forward, 18 thread the wire is towed into its place-, the threads being only designed to favor the insertion of the wires. In this process a difficulty very naturally occurs, that of the thread, or the wire as it may be, cutting into, or even tearing out of the tissue, on the distal side of the wound, as they are pulled upon. To counteract this he employs a crescent-shaped fork to push the suture above the orifice while traction is being made (Fig. 13.) The silver sutures being all passed, As soon as the needle emerges, and the thread comes fairly into view, a long tenaculum is hooked into the loop, and one end drawn through (Fig. 12), Fig. 12. Fig, 13. Exhibits the tenaculum drawing the thread through. after which the needle is withdrawn, leaving the suture in its track. In this manner the requisite number of threads are deposited across the wound. The next step consists in substituting the silver threads for the silk, which is readily accomplished by binding the end of the former into a crook or link, and making fast to it the distal end of the latter. By drawing on the proximal end of the A silver thread secured to the silk one, with the fork in situ to favor the passage through the upper puncture. 19 the second stage of the process consists in the Attachment of the Clamps. Two little bars of silver or lead, a trifle longer than the fistula, are perforated with a number of holes, corresponding to the number of sutures. Through these the upper end of each wire is passed, and fastened by winding it about the bar, or passing it through a shot. (Fig. 14.) This completed, the lower the apparatus in position,* a perforated shot is passed down each wire, and being pressed against Fig. 15. Fig. 14. Tig. 16. Both clamps on the wires, and per- forated shot behind the proximal one. Upper clamp attached. The adjusting fork. ends of the wires are drawn upon, when the clamp will be carried into the vagina, and take its place above and parallel with the upper bor- der of the wound. During this adjustment, a fork of another kind (Fig. 15) is used as a pulley, to prevent the wires cutting into the flesh. In the same manner, the other ends of the wires are passed through the second clamp. (Fig. 16.) the clamp, is then fastened by compression with a strong pair of forceps. (Fig. 17.) The wires are next cut olf short, and bent over the shot. Fig. 17. The Adjustment. The proximal ends of the wires being drawn upon, and the clamp pushed up with the fork at the same time, the raw sur- faces are brought in contact with each other, in doing which, care and judgment are requisite that they be pressed together sufficiently tight to prevent gaping, and yet not so forcible as to en- danger strangulation or ulceration. To maintain The appearance of the wound, when adjusted, Shot compressor. 20 with the suture apparatus in position, is repre sented in Fig. 18. Dr Sims’ Later Operation. Fig. 18. To the clamp there are objections, and these were soon discovered by Dr. Sims, and the opera- tion so modified as to add greatly to its simplicity and perfection. The modifications consist in the introduction of the metallic threads without those of the silk, and dispensing entirely with the clamps, adjusting the wound and securing the wires by twisting alone, which he accomplishes by drawing, with a pair of forceps, the ends of the wire through the slit at the end of his ad- juster, (Fig. 20,) and then, while thus firmly held, the forceps, by a rotary movement, twirls the wires about each other, so as to make them secure. Fig. 20. Exhibits the wound adjusted with the suture apparatus. The After-Treatment. The operation being com- pleted, the patient is placed in bed, on the back, a self-retaining catheter placed in the bladder, (Fig. 19,) and a full dose of opium administered; Fig. 19. to be repeated as often as may be necessary to keep the bowels quiet. The diet is to consist of crackers, and coffee or tea. During the progress of the case, the vulva and other portions of the external genitalia are to be bathed with cold water, a bed-pan being placed under the nates, to collect the fluid as it runs from her person. The urine is to be received on old cloths, as it drops from the catheter. On the ninth or tenth day, the clamps and sutures are to be removed, and if well, the patient required to wear the catheter for several days longer. About the twelfth or fifteenth day, the bowels should be opened by some mild cathartic. fcelt-retaluiDg cauueusr of Sims. Such are the general features of Dr. Sims’ ope- ration, and from this dates the successful surgical management of vesico-vaginal fistula. Sims’ method of coaptating and securing -wires by an adjuster an.t forceps. 21 Operation of Dr. Nathan Bozeman, Formerly of Alabama. done, the requisite number of silk threads are introduced with short, straight, spear-pointed needles, from half an inch to one inch in length, grasped in the jaws of a needle holder. (Fig, 27.) The needle is entered some distance from the freshened border, and carried obliquely through, first the proximal side of the fistula, penetrating as deep as the vesical mucous membrane, and then, after being adjusted to the needle-holder, through the distal side, being drawn through with a pair of long forceps, counter-pressure being- made with a blunt hook, similar to Sims! in- strument. The threads being all passed, each one is securely fastened by its lower end to a sil- ver wire, and as the one is drawn out, the other The name of Dr. Bozeman is well known, both in this country and abroad, in connec- tion with vesico-vaginal fistula. Several pa- pers from his pen have appeared on the subject, all proving unusual dexterity and success as an operator. The chief novelty in his method is what he terms the button suture, (Fig. 21,) eom- Fig. 21. Bozeman’s lead button. posed of a piece of thin lead cut to fit the opening, and having in it small holes answering to the number of wire sutures employed; also leaden crotchets to secure the button. The patient is placed in the position recommended by Sims- a duck-bill Bozeman speculum introduced; and M hile the parts are controlled by a long tenacu- lum or forceps, the edges are pared by straight and curved bistouries; sometimes using the curved scissors. See Figs 22, 23, 24, 25, 26? This Fig. 27. Fig. 22. Fig. 23. Fig. 24. Fig. 25. Fig. 26. Bozeman’s needle hold- claws °nig?*tem’ with*wo with n lts extremity, 7““ a. canula to slide up and down, closing and opening the jaws. Also examples of the Bozekik- needle. 22 takes its place, a fork being used, as in Sims’ method, to guide the sutures and support the soft parts. on wires and button. The operation is finished by cutting off the wires a short distance above the crotchets, and turning an end down on either side. (Fig, 32.) The patient is placed in bed, on her back, the catheter introduced, the bowels kept closed by opium, and an unirritating diet al- lowed. The next step consists in passing both ends of each suture through an instrument called an adjuster, (Fig. 28,) and drawing on the wire, as it is run down, the wound is brought to- Fig. 28. Adjuster. Fig. 29. The sutures alter being passed through the adjuster. Fig. 30. Bozeman’s instrument, having an angular and concave extremity, to model the button to the surface of the vesico-vaginal septum. gether and a set given to the thread, which contributes to so maintain it. (Fig. 29.) The wires are next passed through the perforations in the lead button, and the latter pressed down upon the line of approximation, and made to conform to the surface against which it rests by means of an instrument represented in Fig. 30. To secure the button firmly in place, pieces of lead or crotchets are run down the wires (Fig. 31) and compressed, by a pair of strong forceps, both Operation of Dr. J. Hunter McGuire, Formerly of Philadelphia. The patient being placed in the position re- commended by Sims, the edges are to be pared with a long-handled bistoury, and brought to- gether with the instrument delineated in (Fig. 33.) Fig. 33. Fig. 31. Fig. 32. Button and crotchets adjusted, wires cut and turned down. Exhibits the crotchets being passed down the wires. Representing McGuire’s instrument for yesioo- yaginal fistula. 23 This consists of a plate of silver, having a hole near each extremity, and three needles, slightly curved; soldered to its front surface a second silver plate, of the same size and shape as the first, having fastened to each end a thread-screw? and three holes corresponding in position to the three needles on the other plate, and lastly, two female screws. Fie. 34. Fie. 35. Fro. 36. Application. With a strong pair of forceps the plate supporting the needles is grasped, their points passed through the posterior lip of the fis- tula, and brought out through the anterior one. Through the perforations at either end of this plate are next passed the thread-screws of the other plate, and through its perforations the extremities of the needles. The female screws are next run down the thread, forcing the clamp together, until the edges are in close contact. Operation of Dr. J. Y. Simpson, Of Edinburgh. The operation of this distinguished Scotchman, certainly one of the representative medical men of the age, differs chiefly in substituting, for the Bozeman button, a wire splint, prepared as fol- lows : He takes ten or fifteen strands of metallic thread, and twists them into a cord, the ends of which are then doubled over each other, and plaited round into the form of a circle, which may, being very flexible, be pressed into any figure desired. With an awl, or any sharp- pointed instrument, the required number of holes may be made, by passing it through among the wires. These perforations are for the iron thread sutures. For the introduction of the sutures, Dr. Simpson uses an ingenious needle (Fig. 34), to- gether with a crotchet (Fig. 35), and a hook (Fig. 36.) The needle consists of a hollow tube, with a needle point, one opening being near the end, and the other near where the handle and shank join. The mode of using is readily understood. The wire thread being pushed within a short distance of the upper orifice, the needle is carried through both sides of the fistula, after which, the thread is thrust forward. As soon as it appears, it is to be seized with a pair of forceps, and held while the needle is being withdrawn, thus leaving the suture in situ. By a repetition of this process the requisite number are introduced. He prefers the iron wire, as more easily managed than silver. His sutures are next passed through the Dr. Simpson’s needle, -with a wire inserted. Simpson’s crotchet and hook. 24 openings in the wire splint (Fig. 37), the latter being pressed down over the line of apposition, and the wires secured by twisting with his wire The ends of the metallic threads are next clip ped off close to the splint (Fig. 40), and the after- treatment conducted on the same principle as that of other operators. Fig. 37. Fig. 40. Simpson’s splint adjusted, wires secured, across the lower bar. For paring the fistula he uses straight and an- gular knives; for the passage of the metallic sutures, Simpson’s needle; and for securing the threads, little crotchets or clamps of lead, run down, and compressed with a strong pair of for- ceps. Flis operation dates 1860. Operation of Dr. Isaac Baker Brown. Simpson’s wire sp nt, the threads being carried through the openings in it. twister (Fig. 38), constructed on a plan which was suggested by Dr. Coghill. Fid 369. Fig. 38. Operation of Dr, Robert Battey. The peculiarity of Dr. Battey’s method con- sists in a metallic (lead) button (Fig. 41), having Fig. 41. Battey’s button. a series of holes on one border, and on the other a corresponding number of slits. The upper ends of the wire after being inserted are passed through the holes, the other ends forced into the slits, and both fastened by twisting them about each other. He claims for it a water-tight adjustment. Operation of Collis, Of Dublin. This method, described in 1862, consists in splitting the vesico-vaginal septum along the en- tire circumference of the fistula; turning the vesical side toward the bladder, and the vaginal side toward the vagina; the sutures he employs are silk, and introduced as double threads, with Liston’s needles secured on long handles. When the threads are all inserted, there will be a row of loops on one (the upper) side, and two free ends on the other side of the fistula. A vulcanized quill is next passed through the loops above, and a second placed along the lower border of the opening, and the approximation effected by tying the free ends of the threads firmly around it; it is a quilled suture. Simpson’s "wire twister. The same, with the wire in, and partly twisted. 25 Operation of Dr. Alfred Meadows, Physician-Accoucheur to the General Lying-in Hospital, London, think its exhibition more imperative than in va- ginal fistula. The position and exposure are cal- culated to shock the feelings of any female pos- sessed of ordinary sensibility, and I have in all cases administered this agent with the most sat- isfactory result. The novelty of this method consists in allowing the patient, after the parts are pared, and closed with silver threads, to rise and go about as usual, dispensing altogether with the catheter. He publishes two cases, which it is alleged were treated successfully in this way. I should not feel disposed to subject a patient to such a treat- ment without some further accumulation of data. Assistants. There will be required four as- sistants ; one for the sponges, one for each lower extremity, and one for the anaesthetic. As such an operation is rarely completed in less than half an hour, and may be prolonged to even two hours, the assistant having charge of the anaes- thetic, should be perfectly familiar with his duty. Agnew’s Operation. Having presented the various operations in his- torical succession, I proceed to state the plan of treatment practised by myself for several years, with results the most satisfactory. Nothing ori- ginal is claimed for the method. Except in a few particulars, it does not differ from modes pursued by others. Time to Operate. As a good sunlight is all important to the successful execution of this ope- ration, the forenoon of a clear day should be se- lected, and a room whose windows have an east- ern or southern exposure. Arrangements for the Operation. Among the first things to be attended to is the bed on which the patient is to lie. This should be a firm mat- tress ; but should the circumstances of the pa- tient be such as not to command this, a feather bed may be well beaten down and covered with two or three comfortables, so as to give it a cer- tain degree of solidity. Over that part where the hips are to rest there should be spread a strip of oil-cloth, and over this a folded sheet, the ob- ject being to protect the bed. A low stool should be procured and turned upon its side, over which should be placed one or two folded blan- kets, and over these again a piece of oil-cloth, the whole to be secured by a few turns of a roller. (Fig. 42.) This forms an excellent sup- port, across which the patient is to be turned. Instruments. The instruments which have been and are still being invented for this operation constitute a most formidable armamentarium. I shall content myself by presenting a list of such as compose my own case, and which I have found to answer every purpose. A duck-bill speculum (Fig. 43); two long-han. died scalpels (Fig. 44); one pair of long rat- toothed forceps, slightly curved, with an attach- ment at the end of the handle, embodying the adjustor, for running down the wires and the crotchet to favor by counter-pressure the passage of the needle through the distal side of the fis- tula (Fig. 45); a needle-holder which can with one hand be detached from the needle, or again made to grasp it, and by which the needle can be introduced at any angle (Fig. 46); one pair of long scissors, curved a little on the flat (Fig. 47); a shot compressor (Fig. 48); this instrument, to be efficient, should have strong handles, and the articulation less than half an inch from their ex- tremities; a shot perforator (Fig. 49); two sig- moid self-retaining catheters (Fig. 50); the open- ings in which should be very small, otherwise the mucous membrane of the bladder will insinu- ate itself through them, and become strangulated, rendering its withdrawal impossible without tear- ing the incarcerated portions; one dozen of nee- dles; these should be -constructed with great care, seven-eighths of an inch in length, slightly curved for one-fourth of an inch at the extremity, the cutting-edge confined only to the extent of the curve, and sufficiently wide to allow the proximal part to pass without tugging and pull- ing, as is too often the case. The eye should be well sunken, so as to bury the thread, and the whole so tempered as to bend, rather than break; fine silver wire; some No. 3 shot, and twelve or Fig. 42. Stool covered, over which to place the patient. There will be required two basins, one bucket for cleansing, and another for the bloody water, sev- eral mops or sponges; readily formed by securely tying small pieces of soft clean sponge to the ends of sticks or pieces of whalebone; a six or eight-ounce syringe, and some pieces of ice. There is some difference of opinion as to the ex- hibition of an amesthetic. In no operation do 1 26 Fig. 43, Fig. 44. Fig. 45. Fig. 46. Fig. 47. Fig, 48. Fig. 49. Fig. 50. 27 fourteen inches of light gum-elastic tubing, to slip over the end of the catheter, and thus convey the urine to a bottle or other vessel, placed be- tween the patient’s limbs. over to assistants. The operator now takes the speculum, smeared with oil, and introducing it into the vagina, commits it to one of the assist- ants having charge of the limbs, who draws it firmly toward the rectum, when the air, entering the vagina, expands the tube in the most satisfac- tory manner. (Fig. 51.) The surgeon now takes his seat in a position to command a full view of the fistula, and seizing its lower margin with the forceps, enters the knife from three-eighths to half an inch from the opening, bringing it out just short of the vesical mucous membrane, and by successive sawing movements, paring away, until the entire circumference of the fistula has been freshened. Should the mucous membrane of the bladder protrude, a piece of sponge may be press- ed through the opening to keep it out of the way. The greatest difficulty in executing this part of the operation will be experinced at the angles, or commissures of the opening; and too much care cannot be observed, that no point be over- looked. If it is properly done there should be at least three-eighths of an inch, or more, of oblique raw surface, visible everywhere around the fistu- lous opening. The tendency to inversion of the vagino-vesical septum is so great, that unless a considerable extent of tissue is removed, there will be danger of not having a sufficient amount of raw surfaces apposed to secure adhesion. There will be cases and situations in this freshening process, where the scissors come in more advan- tageously than the knife; such will naturally occur to the surgeon as he proceeds. Where the fistula is very small, receiving, for instance, only the end of an ordinary probe, some advise trans- fixing with a long awl-shaped instrument, and, raising the sides, by a single stroke of the knife cut out a sufficient amount of tissue. There is a very ingenious instrument (the author of which I cannot recal), (Fig. 52), with a conical ex- tremity standing at an angle with the shank, the The patient having removed all her clothing, save a chemise and night-gown, lies down upon the bed, and is brought under the influence of the anaesthetic, nothing having been communi- cated to her about the position in which she is to be placed. When sufficiently unconscious, the stool, prepared as directed, is placed across the foot or side of the bed, and the patient carefully lifted, and placed over it, resting on her abdomen, two or three pillows being laid under her breast and head in such a way as to form an inclined plane. The head must be turned on one side, and a free access of fresh air admitted to her face. The person having charge of the anaesthetic must take his position so as to have a full command of the pulse and countenance, keeping her perfectly passive, without profoundly impressing her. There are periods in the operation when very little need be given, as when the surgeon is wait- ing for the bleeding to cease; and again, when the apposition and adjustment are being effected 5 at such times very little pain is inflicted. The legs, being next flexed upon the thighs, are given Operation. Fig. 51. Fig. 52. base of which is surrounded with sharp teeth, designed for controlling the edges of such fistulas. The apex of the cone is inserted into the opening, and pressed through; then, by withdrawing it, the teeth become fixed into the circumference, when the knife may readily excise at a stroke the included tissue. Exhibits the -woman resting on her abdomen oyer the stool placed across the bed, and the assistants supporting the limbs, one of them also holds the speculum, which has been passed into the yagina. There is another instrument, (Mr. Hilliard’s, of Glasgow,) designed to secure the edges of large fistulas while being pared, and which con- 28 gists of a long shank, with a small thread at its extremity, on which may be secured yarious sized forks for transfixing, and on this shank a sliding rod, bearing a bar which may be pushed forward, and then drawn back between the forks, so as to compress and secure the included tissue. Figs. 53 and 54, exhibit the instrument and its application. There is no objection to having all as the following, will indicate such an apposi' tion; as when the fistula runs to any great extent longitudinally; or when it is low, and either so great a loss of substance, or so unyielding a char- acter of tissue, as to make too much traction when brought together on the lower wall of the urethra, endangering a subsequent incontinence of urine. Fig. 53. Fig. 54. Introduction of the Sutures. This is regarded by many as the most difficult part of the operation. The needle bearing the wire is placed in the grasp of the needle-holder, and whilst the proxi- mal border of the fistula is steadied by the for- ceps, is entered at the middle of the wound, three-eighths of an inch from the freshened sur- face, brought out at the mucous membrane of the bladder, (not including it,) carried across the opening, made to enter the opposite side, and emerge the same distance above its raw surface. The needle-holder is now disengaged from the needle, by simply pressing the upper blade of the instrument while the spring is being pressed for- ward by the thumb, made to seize the extremity now through the upper border of, the fistula, and while the parts are supported, by applying to them the hook at the end of the forceps, (Fig. 55,) the needle is drawm through, turned and Fig. 55. these instruments, if the taste and the circum- stances of the surgeon allow it; but that such are essential, or even necessary to the proper exe- cution of the operation, is certainly not correct. Arrest of Hemorrhage. The bleeding which follows the foregoing process is not generally very profuse, stopping under the application of cold water, or a lump of ice inserted into the vagina, or even under the styptic influence of the atmosphere; but occasionally cases will be met with where the discharge of blood proves both copious and persistent. To control such irregu- larities, I have found a small stream of cold water, steadily directed on the parts from a large syringe, singularly efficacious. Should this not succeed, the stitches should be inserted, and the edges drawn firmly together, when it will cease, just as the approximation in a case of hare lip arrests the hemorrhage. The Direction of Approximation. Most ope- rators favor an approximation of the sides of the fistula transversely, yet there are no reasons why they may not be closed longitudinally, base 15 is an example in point. Such conditions Needle in the grasp of the needle-holder carried through the fistula, and the hook at the end of the forceps placed between the tissues and its point, to favor its passage by counter-pressure. brought out of the vagina. When the sides of the opening- are too wide apart, the needle cannot be made to penetrate both at once, and therefore it must be drawn through them in succession. In this manner the requisite number of threads are inserted, the distance between them being a trifle less than one-fourth ol an inch, (1 ig. 56.) drawn, the blood sponged away, and the patient placed on her back, on the bed prepared for her reception, after which the catheter is to be intro- duced into the bladder, and carefully watehed, to see if the urine flows freely through its canal. In order to keep the clothing of the patient and the bed perfectly dry, a light piece of gum elastic tubing may be drawn over the end of the cathe- ter, and its other extremity inserted into a bottle, which shall lie between the patient’s limbs; or a small earthen vessel or cup may be placed be- neath the instrument, and receive the urine as it drops from its extremity. Fig. 56. After Treatment. Too much importance can- not be attached to the after management of the case, as on this will depend, in a great degree, the success of the operation. The nurse should understand the manner of introducing and re- moving the catheter; if she does not, five min- utes instruction, by showing her the mode, will suffice to enable her to do so, unless she be un- usually dull of apprehension or imitation. It should be examined frequently to see that no obstruction exists, that it does not become mis- placed, and that the urine drops freely. This is imperative, for it often happens for the first twelve or twenty-four hours, that small coagulse of blood are expelled from the bladder, and which may obstruct the instrument. Two catheters should be always on hand, so that one may be introduced immediately on the withdrawal of the other. After thirty-six or forty-eight hours, twice a day will be sufficient to change the in- strument, in the morning, and at bed time; and it can best be cleared of mucus, and other mat- ters, by inserting the nozzle of a syringe into one end, and forcing through it a stream of water. If the bladder is kept perfectly empty, the col- lapsed state of its walls will prevent all tension on the sutures, and diminish greatly the chances of urine getting between the edges of the wound, an accident which will almost always defeat the union. The position best suited to the patient is that on the back, although there are no objections to her turning for a short time on the side to re- lieve a sense of weariness or discomfort. As each is deposited in its proper place the needle is to be removed, the ends of the wire twisted together, and given in charge of one of the assist- ants supporting the thighs. Exhibits the threads passed. Adjustment. In the important stage of adjust- ment, the wire first inserted is separated from the others, and the ends passed through the hole of the adjuster at the end of the forceps. As the latter is slid down, the wire is drawn upon until the edges of the wound are brought into accurate contact. The set which the wire thus obtains, is sufficient of itself temporarily to maintain the apposition. All of the threads are subjected suc- cessively to this process, and while being done, care must be observed that the edges be properly everted, so as to secure the contact of raw sur- faces, and also, that no clot be permitted to lie between them. The next step is to secure the sutures perma- nently, and for this purpose it has been my almost uniform practice to use perforated pellets of shot. These are run down the wires, then seized with the strong compressing forceps, and while the metallic threads are being drawn upon, pressed firmly against the line of adjustment, and then compressed so as securely to maintain their position. The sutures are next cut off, close to the shot, leaving no projecting ends to irritate the soft parts, (Fig. 57,) the speculum with- The next important thought is to lock up the bowels, and keep her free from all pain and un- easiness. For these ends we have no better agent than opium. One or two grains should be given as soon as she is adjusted in bed, after which, from a third to half a grain, three times a day, for five or six days, will answer. From this, until the removal of the stitches, the fourth of a grain, morning, noon, and night, will maintain the effect produced. Ido not think there is any ad- Fig. 57. Exhibits the edges of the wound apposed, the shot com- pressed on the wires, and the latter cut off. 30 vantage in exhibiting this drug, beyond what is just sufficient to keep the bowels quiet; more than this tends to impair the digestion, disturb the secretions, and destroy the appetite. Occa- sionally the patient will be seized with an un- controlable desire to bear down, or an involuntary contraction of the bladder, often driving the ca- theter from the urethra; in such conditions we must resort to enemata, consisting of two or three tablespoonfuls of flaxseed tea, or starch-water, with forty drops of laudanum, repeated once or twice in the twenty-four hours, if necessary. No injections of Avater into the vagina should be practiced, as directed by some; nor any explora- tions with the finger; the vaginal mucus which collects about the wound, and the sutures, does no harm whatever. Should the patient be an- noyed with tympanitic distension of the abdomen, ■which not occurs, a little camphor- water and aromatic spirits of ammonia may he given, or a little turpentine in mucilage of gum acacia, from time to time. Diet. The patient should he allowed a liberal hut unirritating diet. Milk, soft-boiled eggs, cream toast, chicken, or beef broth, mutton chop, with coffee and tea, offer a sufficient list from which to select her food. Removal of the Sutures. On the eighth or ninth day after the operation, the stitches should be removed, and for this purpose the patient may be placed on the side, her limbs well drawn up, and hips over the edge of the bed, before a good light; or she may rest on her knees and elbow. The removal of the sutures not being painful, the ad- ministration of an anaesthetic is unnecessary, un- less the patient be timid, and shrink from the ex- Fig, 58. Shows the suture seized with the forceps and being clipped by the scissors. From Simpson’s work on Diseases of Women. 31 posure; in which event it should be given. The number of assistants requisite for the object in view will be determined by the taking or not taking an anaesthetic. In the former, there will be needed one to take charge of the ether or chloroform, and two to support the limbs and manage the speculum. In the other case, a sin- gle assistant will be sufficient. The catheter be- ing removed, the patient is placed in position, and the speculum inserted and given to the as- sistant. The parts being satisfactorily exposed, the surgeon clears away the mucus from the sutures with a piece of moistened sponge; then taking hold of a shot with the long forceps, lifts it from the parts until the wire is distinctly seen, and with the scissors clips it on the proximal side, (Fig. 58,) straightening the end at the same time by pressing it outward with the blade of the instrument. This done, plant the blade of the scissors against the loop on the distal side, and drawing on the shot with the forceps, the suture will come away by revolving about the blade of the scissors as a point d'appui, (Fig. 59.) several weeks to become distended. Should the union not have taken place, and a considerable portion of the fistula remain unclosed, the cathe- ter may be removed at once, the bowels opened, and the patient allowed to rise and go about as usual. When it is discovered that union has taken place save at a single point, so small, for instance, as to be readily closed by a single stitch, introduce at once that stitch, scarify well the edges, and approximate as before; con- tinuing the management of the case in all re- spects as in the primary operation for six or eight days longer; the probabilities are it will succeed. In one of my cases, (Case 3,) it was so done, and with complete success. No apprehension need be entertained in regard to keeping the bowels so long confined. Causes of Failure. These will be found refer- able to some one of the causes enumerated below. Ist, imperfect freshening of the margins of the fistula; 2d, mal-adjustment; 3d, insufficient tis- sue from loss of substance, thereby rendering the permanency of the sutures uncertain; 4th, diar- rhoea accompanied with tenesmus; sth, soft state of the tissues, permitting the sutures to cut through readily; 6th, enfeebled state of the health; 7th, thin condition of the sides of the opening; Bth, proximity to the cervix uteri. Fig. 59. In regard to the first and second, the fault he- wing with the operator, can only be remedied by care and experience. The third is not always in- capable of being remedied; much may be done by deep stitches, incisions to relieve tension, and rather than abandon the case as hope- less, a plastic operation as practised by Jo- bert, taking a flap from the inner surface of the labium. Should these fail, then it would be better, rather than allow the woman to remain in so miserable a condition, to freshen the outlet of the vagina, and close up the canal, making a common cavity of it and the bladder. The fourth complication (diarrhoea and tenes- mus) will be best met by enematas of laudanum, or suppositories of opium. The sixth (feeble health) by tonics, nutritious diet, and pure air. Seventh, (thin edges of the fistula;) these may be greatly improved by scarifications, and the appli- cation of the nitrate of silver every three or four days to the circumference of the opening. Eighth, (proximity to the cervix uteri); when the fistula is situated in or extends to the cul de sac between the vagina and the anterior part of the cervix, any operation for its closure, including only the vesico-vaginal septum, will be likely to prove abortive. To obviate this difficulty when the or- dinary method falls, the anterior semi-circum- Exhibits one of the stitches after its removal, with the shot attached. The loop should be represented move open. The detail given in what may seem a very sim- ple matter will be appreciated when the reader who has not, may have occasion to perform the opera- tion. If neatly executed, it will save the patient some sharp pain, and not endanger the laceration of the cicatrix. The stitches being all removed, after the manner just explained, the result will be revealed; if favorable, the patient is to be re- placed in bed and the catheter again introduced. After two or three days the bowels should be opened by administering a teaspoonful of castor oil, or a seidlitz powder every four or five hours until a free evacuation is procured. The object in thus exhibiting the cathartic is to thoroughly liquefy, or soften the foecal accumulations, and prevent tension or straining during defeca- tion. This result may be promoted by the em- ployment of an enema of tepid water just before the evacuation. For five or six days after the re- moval of the stitches, the patient must continue in bed, and wear the catheter, in order to take off all tension from the cicatrix, and allow it to at- tain considerable consolidation. After this, the instrument may be removed and she may be al- lowed to walk about, remembering to pass the urine frequently, and not allow the bladder for 32 ference of the cervix should be freshened, and the veslco-vaginal, similarly treated, stitched to it, thus turning the os into the bladder. In one of my cases, (Case 2,) such a plan was suc- successfully adopted, and the women continue to menstruate regularly through the bladder with- out any inconvenience whatever. was tried, two or three weeks subsequently, with a similar result. The operation adopted was, I presume, that of Dr. Sims, with the addition of the Bozeman button, as she described the em- ployment of silver wires, and a lead plate. Since the accident, she informs me she has not men- struated ; but alleges, that when the period comes round, a very copious flow of urine takes place, and continues for two or three days. I was in- vited to see her, July Ist, 1859, by Dr. R. K. Smith, Chief Resident Physician; and in com- pany with himself, and Dr. Elwood Wilson, made an examination. An extensive transverse rent was discovered, extending from one side ot the vagina to ihe other, and situated at the has fond of the b’ad ler. Through this protruded a considerable mass of the mucous membrane of the bladder. At the request of Dr. Smith, and her own earnest entreaty, I consented to attempt her relief by an operation. Failure ought not in any way to discourage either patient or the surgeon. The rule is to operate until the case is cured, as such a consummation is certain, unless there be some unusual state of things present. One caution is necessary here: The operation should not be repeated until at least six weeks have elapsed. Sequels. There sometimes follows a successful closure of the fistula a certain degree of inconti- nence of urine, which is due generally to one of two causes. First, loss of power in the sphincter vesicm, permitting the urine to escape when the bladder is distended, or during coughing, sneez- ing, or even laughing. This condition may fol- low when fistula -has been at the neck of the bladder. The second cause is shortening of the lower wall of the urethra, with a patulous condi- tion of the meatus—as in cases where the open- ing is low down, with such a loss of substance that when the stitches are inserted, and the parts drawn together, the traction produces the effect already stated on the urinary canal. On the 23d of August it was performed in the presence of Drs. Smith, Wilson, Levis, McClellan, Darby, Nichols, and the inter- nes of the house, the bowels having the day pre- vious been well emptied. The steps of the opera- tion consisted in placing the patient under the in- fluence of ether, turning her over, supported on the arms and knees, and exposing the fistula by inserting rectangular or lever speculm along the walls of the vagina, which enabled the assistants to draw the parts well asunder. The edge of the fistula was next seized with a pair of long rat- toothed forceps, and well pared by means of a long-handled straight bistoury. As soon as the bleeding ceased, nine stitches of silver thread were inserted, the needles being guided by the needle- holder of Mr. Gemrig, (see Fig. 46, page 273.) The wires being brought out of the vagina, the opening was drawn together by passing the two ends of each through an adjustor, which was slid down to the wound, while the threads Avere firmly maintained between the fingers. Not being alto- gether satisfied rvith the principle of the Bozeman button, as it prevented the operator seeing the approximation, I had a fenestrated one construct- ed out of lead (Fig. 60.) Through the perfora- To remedy these defects, tonics, cantharides, and strychnia have been prescribed; yet, after all, time is the great restorer, as the parts tend gradually to assume their original condition. Should the incontinence be so great as to produce much discomfort, an elastic ring pessary may be passed within the orifice of the vagina. In one case, (No. 14,) I had to resort to this, with the most complete success. Keport of Cases of Vesico-Vaginal Fistula Suc- cessfully Treated, and which have furnished the basis of the previous papers. Case 1. F. H. was admitted into the Philadel- phia Hospital, Blockley, suffering from a vesico- vaginal fistula. The folloAving account of the ac- cident Avas obtained from the patient: In Jan- uary, 1858, she gave birth to a child. Her labor was exceedingly difficult and prolonged, to aid which ergot was freely administered by her med- ical attendant. After delivery, for several days she was unable to pass urine; Avhich, continuing to accumulate, and not being relieved by instru- mental interference, she suddenly felt a large gush of vrater escaping from the vagina, since which time the urine continued to fIoAV by this route. In May, 1858, her physician performed an operation for her relief. This failing, a second Fig. 60. tions in its centre-bar the wires Avere next passed, the button run down over the line of adjustment, and there maintained by passing the ends of each suture through a perforated shot, which, being slipped down in contact with the button, was there secured by compressing it between the blades of a strong pair of forceps. The wires were next collected together, brought out of the vacina, and wrapped with adhesive plaster to prevent excoriation 5 and finally, the patient placed in bed, on her side, a catheter (Sims’) was introduced into the bladder, and the urine recieved on cloths placed beneath the end of the instrument. Half a grain of opium was directed to be given tAvice daily, and the diet to consist chiefly of arrow-root and cream. The catheter was to be closely watched that it should not become obstructed, to obviate which, it Avas to be removed once or tAvice a day, and cleansed. No consti- tutional disturbance occurred, nor was there any local soreness experienced. On Wednesday after- noon, September Ist, being ten days after the operation, I proceeded to remove the button and sutures, when the union Avas found to be com- plete. As a precautionary measure the catheter was directed to be Avorn eight days longer. On the twelfth day her bowels were opened, and again locked up for five or six days. Ten days after the removal of the ligatures she was al- lowed to rise from her bed and walk about. Hospital, under my charge, where, after some preliminary treatment to improve her general condition, she was operated on by my usual me- thod, seven silver sutures being required to close it properly. On the eighth day the stitches were taken out, and the Avound found to be only about one-half closed. On carefully examining the parts, and reflecting over the former failure, I thought I discovered the true source of difficulty, which subsequent events confirmed. The prox- imity of the fistula to the cervix uteri, the latter organ being somewhat retroverted, prevented an accurate adjustment; indeed the os was turned into the fistulous opening, and pressed toward the bladder. Profiting by this observation, at the second operation, undertaken nine Aveeks subse- quently, I determined to turn the os into the opening permanently. With this end in view, the inferior semi-circumference of the fistula was well pared. Next the posterior half of the cervix uteri, after which eight silver sutures were intro- duced, and secured by the shot, the ends of the wire being cut off close to the latter. The os uteri was by this method turned into the bladder. Nothing worthy of note transpired during the subsequent progress of the case. On the eighth day following the operation the parts Avere exam- ined with a view to remove the ligatures, which were found in such excellent position, Avithout any surrounding irritation, that, at the sug- gestion of Dr. E. Wilson, who rendered me valuable service in both operations, I was in- duced to allow them to remain for two days longer. On the tenth day they Avere clipped out, and to our great satisfaction the fistula closed. Since that time this woman has menstruated re- gularly through the bladder; enjoyed comfortable health; been able to support herself as servant to a private family, and certainly rid of a most dis- tressing and disgusting malady. Two years after I operated on this same patient for strangulated umbilical hernia, from Avhich she recovered with- out any unusual symptoms. It is not often we meet Avith an example of so many grave acci- dents, operations, and good recoveries, in one person, as are presented in the narrative of this poor, friendless Irish-woman. Case 2. A. M., an Irishwoman, about thirty years of age, during a severe labor with a first child, ruptured her uterus, the child escaping into the abdomen. The foetal head had not passed below the superior strait of the pelvis, the diameters of which were contracted. The case being under the care of the medical officers of the Nurses’ Home, Dr. E. Wilson was immedi- ately summoned to her aid by the attending phy- sician, Dr. Scholfxeld. The propriety of the abdominal section admitted of no question. The operation was accordingly performed by Dr. Wm. Byrd Page, the child removed through the pari- eties of the abdomen, and the life of the mother preserved. Sometime afterward it was discovered the rent in the uterine walls had extended through the cervix and involved the vagino-vesical septum, giving rise to a fistula. After the restoration of the woman’s general health, she was placed in St. Joseph’s Hospital, and at considerable in- tervals three unsuccessful attempts were made to close up the orifice, which was situated near the cervix uteri, and running in an oblique direc- tion, about three-quarters of an inch in extent. Two of these operations were skilfully performed by the Bozeman method, employing as a reten- tive mechanism a lead plate or button. The pa- tient was afterward placed in the Philadelphia Case 3. Catherine , a young woman aged 19 years, was seized with labor-pains, September, 1858, at the Philadelphia Hospital. In conse- quence of the great size of the foetal head, it became completely impacted in the pelvic cavity. After ineffectual efforts to deliver with the for- ceps, the operation of craniotomy was resorted to by Dr, R. K. Smith, Chief Resident Physician, and the child readily removed. In consequence, however, of the prolonged pressure sustained by the anterior wall of the vagina, a slough in a few days separated, opening a communication be- tAveen that cavity and the bladder, through which the urine flowed. An examination, some weeks after, showed not only the existence of this fistula, but the canal of the urethra closed by inflammatory deposit. A trocar was at once carried through the obstructing material into the bladder, followed by a catheter, which Avas re- tained for eight days, only being removed for the purpose of cleansing. In this manner the ure- thra Avas restored. bled with for some time previous to the operation, harassed her so much, notAvithstanding the free administration of opium, as sometimes to drive the catheter out of the bladder. On December the 27th, ten days after the ope- tion, the sutures were removed, and the wound found to have united, save at one single point, which was subsequently and permanently closed by a single stitch. The catheter was kept in the bladder a few days longer, in order not to en- danger the cicatrix. This patient was watched with great care by Drs. Darby, Richardson, and Taylor. On the 16th of December following, the parts having become sufficiently callous, an operation was performed for her cure; her bowels being well opened the day previous, after Avhich It grains of opium were administered. Case 4. Mary II , aged 25 years; unmar- ried, temperate, and a Philadelphian by birth, was received into the Philadelphia Hospital in September, 1858, pregnant. This was her second pregnancy. In her first labor, she states she Avas brought to bed on Monday morning, and delivered the folloAving Thursday morning of a still-born child; the delivery being brought about, as she says, by the physician in attendance using 11 forcing powders.” She Avas placed under the influence of a mix- ture of ether and chloroform, turned upon her abdomen, over a stool Avell protected, the limbs being supported by two assistants, and the parts exposed by a Sims’ speculum. The fistula, which was transverse through the trigone vesicce, and exceeding an inch in its greatest diameter, could now be Avell seen. The edges were seized with the long rat-toothed forceps, and with a long, straight, sharp-pointed bistoury, pared in their whole extent. Seven needles, slightly curved at their points, each armed with a silver thread, were carried successfully, by means of the needle holder figured in cut No. 46, through the edges of the wound, down to, but not into the vesical mucous membrane. These sutures being brought out of the vagina, Avere passed through the adjus- tor, in succession, and draAvn upon as the latter was passed down, thus approximating the edges very completely. Perforated shot were next run down over the wires, and clamped by means of the compressor. The sutures Avere noAv tAvisted together, and passed through a small tube of rubber to protect the parts, and the catheter car- ried into the bladder, to which was attached a flexible piece of gum elastic tubing, designed to convey the urine into a bottle, properly placed between the limbs of the patient for its reception. The patient being placed in bed, an anodyne was administered; the Avhole time consumed, includ- ing etherization, did not exceed one hour. Everything progressed favorably until the third day, when, notwithstanding opium had been given to keep the bowels in a quiescent state, diarrhoea, attended AArith considerable straining, came on, but which was at length controlled by enemata of laudanum. To make the case more embarrassing, a cough, which she had been trou- On the 29th October, 1858, at ,A. M., labor commenced. At 6 o’clock, P. M., it was suffi- ciently advanced to establish the existence of a breech presentation in the first position. At 2, P. M., the foetus was expelled as far as the um- bilicus; the limbs being much discolored from long-continued pressure in the pelvic cavity. The delivery of the head was delayed by the chin leaving the breast, requiring finally the agency of the blunt hook to bring it down; the labor being completed at 5 o’clock, making from its commencement thirty-seven hours and a half. Alarming hemorrhage followed, which was ar- rested by the removal of the placenta, frictions OArer the hypogastrium, and ice. The child AATeigh- ed 9J pounds, and measured 22 inches in length. For twenty days the woman passed her urine naturally, and without pain or difficulty. On the tAventy-first day it commenced to Aoav through the vagina; a slough having separated, and formed the fistula. Its situation was at the tri- gonum vesicce, and about six lines in its greatest diameter. On the 14th of February, 1859, the parts hav- ing attained the requisite healthy conditions, the operation for cure was executed. An aperient was given the day previous. The Avoman was placed under an anaesthetic of ether and chloro- form, (three parts of the former to one of the latter, by weight,) turned over the padded stool on her abdomen, the hips being well elevated, and the fistula being exposed by introducing into the vagina the duck-bill speculum. The edges were next extensively denuded, and after the bleeding ceased, five silver sutures were inserted, and their ends brought out of the vagina, and the edges closed by the adjuster. Over each was passed a shot, and the stitch made secure by the compressor clamping it on the wires. The su- tures were gathered together, and passed through a piece of elastic tubing; the woman placed in bed, and the catheter at once inserted into the bladder, over the end of which was slipped the light gum-elastic tube, to oonvey the urine into a bottle properly placed in the bed. The bowels were controlled by opium, one-half grain, three times a day, for two days; after which, the one- third of a grain three times a day. The diet consisted of nutritious broths, with some fari- naceous articles. Nothing unusual occurred; and on the eighth day the stitches were removed, and the cicatrization found to be complete. The bowels were gently open on the ninth day, and the catheter continued five days longer. On the sixteenth day she was allowed to sit up, and on the twentieth day permitted to exercise in the ward. in the bladder, and carefully watched that it should not become obstructed with mucous or blood. This girl proved to be a very self-willed and troublesome patient. On the ninth day after the operation the stitches were taken out, and the fistula, as we believed, closed. She was kept in bed with the catheter in the bladder for five days longer, after which she was allowed to sit up, the instrument being used four times daily, and worn at night for three days more, when it was laid aside, and the patient allowed to walk about. She was retained in the house for two weeks longer, and then dis- charged well. About four months later this young woman re- turned, seeking admission, alleging that the fis- tula had re-opened. She had evidently, from her own statements, been leading a very irregular life. On carefully inspecting the parts, a small open- ing, admitting the end of a probe, was detected in the middle of the cicatrix. There could be no doubt this fistula had opened during her ab- sence, as the bladder was perfectly retentive, and the urine passed voluntarily in a full stream for the two weeks previous to her leaving the hospi- tal. Four operations were performed unsuccess- fully to close this small hole, at intervals of eight weeks, and requiring but three stitches when freshened. I was satisfied there was something wrong, as there was nothing in the case which could explain this indisposition to heal. I sus- pected the woman was more anxious to have a home than to get rid of her disease, and doubt- less, at night, in the absence of the nurse, with- drew the catheter, introducing it herself before her morning visit. Accordingly, on discovering my failure in the fourth operation, without wait- ing for some time to elapse, the parts were again denuded, and two sutures inserted; relays of nurses were kept night and day by her bed, and on the eighth day the parts were examined, and the sutures taken out. The opening was closed. The bowels had been confined for 17 days, and after wearing the catheter four days longer, she was allowed to dispense with its use. This case was reported in detail, by Dr. Darby, in whose care the patient was, Med. and Surg. Reporter, vol. 1, page 435. Case 5. K. D., a Scotch girl, unmarried, 20 years of age, was admitted into the Philadelphia Hospital in April, 1859, pregnant. Her labor, which occurred in September, was difficult and prolonged, the head presenting, although the position is not known. She was finally delivered by the forceps, of a dead child, at the full term. One week after, the urine was observed trickling from the vagina, and, on examination, some three weeks subsequent, a fistula was discovered, about seven lines long, and situated at the vesicle tri- angle. Two months after her parturition she was transferred to the Woman’s Surgical Ward, and prepared for an operation, by washing out the vagina every day with a solution of tannic acid, to give some tone to the parts; regulating the diet, and improving her condition by tonics. After the lapse of another month, she was con- sidered well enough to justify an operation. This was performed in the presence of the house resi- dents, in the manner already detailed in the pre- vious cases. Seven silver threads were intro- duced (the patient being under the influence of ether and chloroform), and these stitches secured with the usual clamp of shot. Instead of bring- ing the wires out of the vagina after the adjust- ment, they were cut off close to the pellets of shot. Opium was administered in doses sufficient to keep the bowels closed, and the catheter kept My surmises in regard to the cause of failure were corroborated by her own confession. One year after, this po'or unfortunate girl applied again for admission, not on account of the fistula, which remained well, but evidently dying from tuberculosis, induced by a life of dissipation. Case 6. Ann II , a native of Ireland, aged 33 years, and a resident of Delaware County, Pennsylvania, was admitted into the Philadelphia Hospital on the 24th of January, 1860, with a vesico-vaginal fistula, situated three-quarters of an inch below the upper extremity of the vagina, four lines in length, and running oblique to the longitudinal axis of the canal. About ten months before her admission into the institution she had been delivered by instrumental means of a child, after a difficult labor of thirty-six hours duration. I believe this was her second child. A few days succeeding this she discovered her urine dribbling away, without being able to exercise any control over its escape. As the avoid an’s health was by no means good, the first attention Avas directed to its improvement, which, under the employ- ment of mineral tonics, and a good diet, AAras, in a few weeks, in a good measure restored. The last of the succeeding month (February) the op- eration Avas performed, while under the influence of ether and chloroform as an anaesthetic. Four sil\7er sutures were introduced, and secured by means of a Avire tAvister. The wires were next cut off very near to the wound, and the ends turned doAvn in such a manner as not to irritate the posterior wall of the vagina. The catheter was worn uninterruptedly, and the bovrels locked up with opium. The case progressed without any unfavorable symptoms Avhatever, and on the eighth day the stitches Avere removed, and the union found to be complete. The patient was retained in the hospital nineteen days longer as a precautionary measure, during four of which she was obliged to wear the catheter. catheter was introduced into the bladder, and the patient placed in bed, with directions to adminis- ter the usual pills of opium. Difficulty was expe- rienced in keeping the catheter clear, it becoming obstructed with clots of blood for three or four days. She suffered also, throughout the whole treatment, with flatulent colic and some diarrhoea ; the last Avas controlled by enemata of starch- water and laudanum, morning and evening. Her appetite failed, and her stomach became irrita- ble, for the relief of Avhich alkalies were pre- scribed with benefit. At the expiration of nine days, the sutures wese examined, without being at all sanguine as to a favorable result. Several had ulcerated out, and no disposition was exhibit- ed at any point to heal. They were all removed, and the patient, in a few days, ordered out to take exercise in the open air. Yegetable tonics, with an occasional mercurial, followed by the tincture of the chloride of iron, wrought a wonderful change in her condition, so that in six Aveeks after, avc deemed her health sufficiently good to undertake a second operation. The edges of the fistula had changed. Instead of being spongy and soft, they had become firm. There Avas no more than the ordinary bleeding after the application of the knife in vivifying the margins. Six metallic threads Avere introduced, secured each by the shot-clamp, and the usual treatment pursued. Not a single untoward symp- tom occurred, and after eight days the stitches were removed, and the union found complete. Dr. Recio, one of the resident-physicians of the hospital, Avas unremitting in his care of this pa- tient. Case 7. Matilda L., aged 24 years, was sent from Wilmington, Delatvare, by Dr. Pepper Nor- ris, She entered the hospital August, 1860. An examination proved the existence of a vesico- vaginal fistula at the has fond, transverse in di- rection, and about six lines in length. It fol- loAved her first labor, which Avas sufficiently difficult to demand delivery of the child (dead- born) by the forceps. The presentation was a cephalic one, and she heard nothing said about anything being wrong. A few days after, she could not state lioav many, the urine began to Case 8. K. C., born in Ireland, recently from the vicinity of Bordentown, N. J., aged 28 years, entered the hospital in the spring of IB6o*, with a vesico-vaginal fistula situated a short distance above the neck of the bladder, oblique in position, and about five lines in extent. The entrance to the Amgina was much constricted, rendering the exposure of the fistula difficult. The accident occurred about eighteen months before, in a first labor, in Avhich a dead female child was deliv- ered by instruments. She is not certain that the head presented. Difficulty Avas experienced in adjusting the instruments, and she felt as though the vagina had been torn at the time. As the fistula was seated above the stricture, it became necessary to institute the preliminary treatment of dilatation, Avhich Avas effected by gum-elastic bougies, after two weeks. This i flow from the vagina. The woman was pale, ctamemic, and had but little appetite. She was bplaced on a regimen of tonics and nutritious food, Tin order to improve her health. Some progress atwas made, but by no means equal to our expecta- htions, and after Availing five weeks, I concluded to make an attempt for her cure. On paring the edges the bleeding became very profuse, and continued, notAvithstanding the application of ice and a stream of cold Avater from the nozzle of a syringe. To arrest this, seven stitches were in- serted, and the edges draAvn firmly together. Even these did not entirely control the haemor- rhage, some considerable oozing continuing. The * The record of this case being lost, I am unable to refer with certainty to the date of her admission, my own notes only con- taining the details of the operation. 37 accomplished, the operation was performed in the presence of the medical residents, the patient being under the influence of the usual anaesthetic of ether and chloroform. After the edges were sufficiently denuded, six metallic (silver) threads were introduced, the parts brought in contact by passing each suture in detail through the adjus- tor, and securing the apposition by the shot- clamp. The rigid character of the vaginal walls, in consequence of the amount of cicatricial tissue, rendered all manipulations difficult. Penrose, Drs. La Roche and Boardman. Nine silver threads were inserted and secured by the shot-clamp. The usual course in regard to opium, catheter, and diet was observed. No- thing unusual occurred, worthy of' note, during the treatment. On the ninth day the stitches were removed, and the wound found united. The catheter was continued five days longer, the bowels being gently moved on the twelfth day after the operation. This patient I saw over two years after, when she stated she remained per- fectly well, and was about four months advanced in her second pregnancy. From this until the ninth day following, no- thing of importance occurred. The threads were on this day removed, and the fistula found about two-thirds closed. She was allowed two months’ respite, occasionallly having a large-sized bougie introduced to counteract the persistent tendency to contraction of the vaginal canal, after which a second operation was executed, in which four stitches were inserted. A good deal of bleed- ing from the bladder followed for two days succeeding this, rendering it difficult to keep the catheter unobstructed. On the third day it ceased, and the case progressed very favorably during the remaining period of her treatment. The stitches were cut out on the ninth day, the union having taken place throughout. This wo- man, after getting about, complained of some in- continence, and I was disposed to believe some minute orifice must still exist, although undis- covered. Since, however, the nurse informs me, this disappeared, and she left well. Case 10. L. L., aged 35 years, from Pennsyl- vania, was admitted to the Philadelphia Hospital in the month of April, 1864, suffering from a transverse vesico-vaginal fistula, three-quarters of an inch in extent, and situated in the has fond, with the complete destruction of the ure- thra. She was married at the age of 17 years, and 15 months after fell in labor with her first child at full term. She knows the child pre- sented by the vertex. After being in labor forty- eight hours the forceps was applied, and after one hour the child was extracted dead, a male, and more than ordinarily large. Her urine, she states, was not drawn off, and she was never con- scious, after delivery, of passing her water the natural way. This fistula was therefore over seventeen years’ standing. The vagina had un- doubtedly sustained much injury, as it was greatly narrowed in its whole extent. Her health was poor, and in no condition for an operation. She was placed on a tonic course of treatment, with some improvement, and on the 9th of June, 1864, I concluded to make an attempt for her relief. The edges were pared, and fifteen wire threads inserted, securing each with the shot, which closed the vesico-vaginal rent satisfactorily. A catheter was placed in the bladder, and worn for nine days, when the stitches were removed; no attempt even at union seemed to have occur- red. Increased attention was now given to her general health, and on the 28th of the following October, a second attempt was made, twelve stitches being inserted, and with an unsuc- cessful result, union having taken place only to the extent of one-third of an inch. On the 3d of March, 1865, a third operation was executed, nine sutures being used, and the result again unfavorable, On the 2d of June a fourth opera- tion was performed, in which, nine threads were employed, and this time with complete success. During the period she had been suffering from this fistula she had five miscarriages, all occur- ring at the fourth month. It is contemplated to - Case 9. Mrs. GL, an Irish woman, aged 40 years, who married late in life, fell in labor with a first child January, 1863. She states her pains commenced on a Friday, and gradually increased in severity until the following Sunday, when she became so exhausted as to render the application of the forceps necessary to complete delivery. The child, a male, head presentation, was born dead. The bladder had not been catheterized. At no time after that had she a sensation like urine passing by the urethra. Her getting upwas slow, and it was many weeks before she was able to walk, in consequence of a feeble state of the limbs, with diminished sensibility. In No- vember, 1863, she was kindly referred to me by Prof. F. G. Smith, of the University of Pennsyl- vania, to whose care, she had been sent from the country. On examination, a fistulous opening was found between the vagina and bladder, situ- ated at the has fond, three-fourths of an inch in extent, and transverse in direction. On the 10th of November, I operated in my usual manner, assisted by Profs. F, G, Smith, 38 attempt next the formation of a urethra for this patient. lowed some to escape, and advised the use of tonics, with the extract of nux vomica, and not to allow the urine to accumulate. The difficulty was not relieved, and, on a second careful exami- nation, an opening, of almost capillary dimen- sions, was discovered at one angle of the cicatrix. The part was denuded, and two stitches inserted, which completed the cure, as she has since been perfectly well. Case 11. Mrs. H., aged 28 years, residing in an adjoining State, fell in labor with a first child. Her parturition was slow, vertex presentation, and becoming exhausted, the forceps was applied for her relief, and the process completed by the removal of a dead female foetus at full terra. Four or five days following, her urine was dis- covered dribbling over the genitalia, and on in- quiry, by her physician, little doubt was enter- tained that a fistulous opening existed between the bladder and vagina. On the 24th of May, 1865, eight weeks after recovery, I visited her, and on examination discovered the opening situ- ated near the cervix vesicae, oblique in direction, and about three-quarters of an inch in extent. She was placed under an anaesthetic of ether, and after freshening the margin of the opening, it was brought together by six sutures of silver wire, and clamped with shot, the usual detail of treatment being observed. In consequence of some pleuritic symptoms occurring about the eighth day, the stitches were not removed until the tenth day, when the wound was found thor- oughly united. Case 13. Mrs. •, aet. 30, a small delicate lady from a distant land, in a first labor, greatly protracted, discovered, after five days, her urine running from her without control. She was in- formed that a fistula existed, and was for some time treated by cauterization. Becoming in the meantime pregnant, all remedial measures were suspended. Her confinement took place in Phil- adelphia, under the care of Dr. Stroud, seven weeks after which, I was invited by the Doctor to visit her and examine the case. The fistula was quite small, and situated in the vesicle tri- angular space. On Sept. 12th, 1865, assisted by Drs. Stroud, Hunt, Rodman, and Townsend, I performed the usual operation, inserting, after the edges were properly denuded, four silver su- tures, and securing them with shot. The subse- quent treatment was conducted by Dr. Stroud. The only troublesome symptom arising in the progress of her case was occasionally a violent spasmodic contraction of the bladder, expelling the catheter, but which was overcome by enemata of a little thin starch-water with laudanum. On tho ninth day I removed the sutures, the opening being successfully closed. Yery recently I have heard from this patient, who continues to enjoy perfect health. Case 12. Mrs M., of Philadelphia, aged 30 years, applied to be relieved of a vesico-vaginal fistula. A few months previous she had been delivered of a dead child (her first), after being in labor forty-eight hours. It was a breech pre- sentation, and after the extrusion of the body, the head was retained for several hours. At what time after, the opening occurred she could not determine, as she had no sensations decisive of the accident, but believes the urine dribbled ever after her labor. Case 14. Mrs. G., mt. 29, residing in a neigh- boring village, went into labor -with her first child. Her pains were severe and exhausting. The head of the child presented, and after thirty- six hours, the forceps were applied and the child extracted, dead. Her urine had not been re- moved during labor, and she thinks that, four days after, it commenced escaping from the va- gina. On the 24th of November, 1864, I operated, assisted by Drs. McLerny, Wilson, and Allen. The opening was situated about three-quarters of an inch above the cervix vesica;, transverse in di- rection, and about six lines in extent. It was freely freshened, and closed with eight silver sutures. Nothing unusual occurred during the subsequent course of the case, and on the ninth day the sutures were removed, the opening to all appearance closed. After getting up she was under the impression all was not quite right, as she was conscious of an unusual moisture at the outlet of the vagina, and her clothing had a urinous odor; still she was able to pass her water in a fair stream. On examination I failed to de- tect any opening, although the bladder was not injected, the cicatrix looking so perfect. I was disposed to believe the urethra or neck of the bladder had not entirely recovered tone, and al- When I first visited her, she informed me a year and a half had elapsed since the accident, and that three operations had been attempted without success. On examination a double fistula was discovered, each running transversely through the vesical triangle, and separated from each other by about three-eighths of an inch. This condition was easily explained by referring to the previous operation—the middle of the wound uniting, and the extremities remaining open. Assisted by Drs, Morton, Sutton, Agxevv, and 39 Weightman, I operated a few days after, by par- ing the edges of each, and closing one with five, and the other with four sutures. Everything progressed well until the third day, when she was seized with pain in the abdomen, with free Heeding from the vagina, which at first I was disposed to believe was a copious menstruation. Her bowels also became disturbed, and her ap- petite failed. Opium and warm fomentations re- lieved her pain and diarrhoea, but the bleeding continued for seven days. On the ninth day, the threads were removed, one fistula being found closed, and the other open. After this the wo- man became pale and dyspeptic, and in no con- dition to justify an operation. Under a properly regulated diet and tonics, she improved rapidly in general health, and in the meantime became again pregnant. Two months after her confinement, on the 4th of November, 1865, assisted by Drs. Patterson, Hall, and Townsend, I operated, closing the opening with nine metallic threads. Not an unpleasant symptom occurred, and the sutures were removed on the ninth day following, the wound proving to be closed soundly in its entire extent. An interesting fact connected with this case was the disposition, if she allowed her blad- der to become too much distended, to some in- continence. To correct this an elastic-ring pes- sary was introduced, which, by its pressure on the neck of the organ, effectually relieved the dif- ficulty. Mortox, Hem'son, and the hospital residents, I executed the operation described in the previous cases. As the neck of the uterus formed one side of the fistula above, the os looking into the bladder, it was necessary to freshen it, and secure it to the opposite side. The opening was closed longitudinally with thirteen sutures. Not an unfavorable symptom followed the operation, and on the ninth day these stitches were taken out, and except at a single point, where the vaginal wall blends with the cervix uteri, a solid union secured. To close this a second operation was performed, eight weeks after, requiring three Stitches, and resulting in complete closure. Anomalous Symptoms.—Death.—Pyeexnio Peri- tonitis. Reported by Dr. William Pepper, Resident Physician. Case 16. Cornelia Augusta Handy, mt. 24, color- ed, was admitted to Pennsylvania Hospital April 14th, 1866, suffering with a vesico-vaginal fistula of very great size, resulting from prolonged second stage in her first labor, six months ago. She has been for years in delicate health, though evincing no positive sign of organic disease'. Hr. Agnew operated upon her, Thursday, Apx-il 19th, 1866, the edges being pared and brought to- gether, antero-posteriorly, by thirteen silver sU- tures, clamped with shot. The two upper stitches including the involved anterior lip of the os uteri. A full opiate was administered, and a self-retain- ing catheter introduced. The urine came readily through catheter, and the woman did well until the afternoon of Saturday, April 21, 1866, when she had a very slight chilly sensation, followed by scarcely any fever or sweat. The following morning I found her with a dry hot skin, rest- less, lying on her back with legs drawn up, com- plaining much of abdominal tenderness. The entire abdomen was sensitive to pressure, rather more markedly so in the hypogastric region than elsewhere. There had been very little hemor- rhage, and the catheter remained quite clear. She was at the time under mild opiate influence— having taken gr. i. twice daily. Bowels consti- pated. Opium and emollient applications to ab- domen were ordered, but during the day she had four or five thin serous stools, and vomited a number of times, the abdominal symptoms re- maining unabated. No recurrence of chill. Case 15. S. G., aged 25 years, a native of Ire- land, was admitted into the Pennsylvania Hos- pital, October the 10th, 1865, suffering from a vesico-vaginal fistula since the April previous. It occurred as a consequence of a tedious labor with her second child, forty-eight hours having elapsed before it was delivered. Her physician stated to her it was a cross-birth. No instru- ments were used, but the leg of the child was broken in two places. Of course the foetus was dead. The time she passed her urine first through the vagina, she could not determine, but thinks before the second day after her confinement. At the expiration of two weeks she got up, but found herself so weak on her limbs as to be unable to walk. Her first labor was not difficult. After her recovery, two operations were performed for the closure of the fistula, by her physicians, both unsuccessful. On examination, after her admis- sion, the fistula was found to extend longitudi- nally from the neck of the bladder to the os uteri, and inclining to the left of the cervix passed along its entire length. April 23d. Much the same. Diarrhoea and vomiting persisting. Complains of abdominal tenderness. Tongue furred in centre, merely dryish. Pulse rapid and small. Catheter runs freely, but little blood passing. No chill or chilly sensation. Opii, gr. J, calomel, gr. ss., q. t. h. Hop-poultice to abdomen. Light diet. On the 24th of October, assisted by Drs. Hunt, 40 April 24. Expresses herself as feeling better Less abdominal tenderness; Belly not'distended No vomiting. Less diarrhoea. There is, how- ever, extreme huskiness of voice, and mental de jection. deeply stained of a yellowish hue. The blood in the cerebral veins was clotted, as it was in most of the vessels of the body. Thorax. Lungs anaemic, congested postero- inferiorly, but contained no pysemic deposits. Bronchial glands not enlarged. Heart contained no fluid blood, and a very small, quite firm coagu- lum in right ventricle, extending into pulmonary artery, but by no means filling its calibre. Healthy in structure, though these organs, as all the others, were stained yellow. April 25th, 26th, 27th, 28th. Remained in much the same condition, excepting that great jaundice came on, the conjunctive being deeply yellow, and the jaundice-tinge showing through the dark skin. The vomiting has not recurred; but, despite the free use of opium, she had several thin stools daily. The calomel and opium were suspended after sixty hours, as the abdominal tenderness disappeared almost entirely; the pulse became less frequent, and the skin less parched and dry; and Huxham’s tincture of bark, with nitro-muriatic acid and a small amount of stimu- lus, were ordered. There was nothing like a chill or intermission in the febrile movement. The voice remained very husky and feeble, and she evinced great hpbitude. Abdomen. On opening the abdominal walls, there was a gush of thick yellowish, ochre-colored fluid, identical in thickness, color, and smell, with the fluid so often seen in pyasmic pleurisies, and upon examining the cavity of abdomen, it con- tained at least Oij. of this fluid. All of the vis- cera were coated more or less with yellowish cheesy-looking lymph, although the spleen, greater omentum, and ilium were so to a most marked degree. Upon stripping off this lymph, the sub- jacent peritoneum seemed almost entirely healthy, not having even an excoriated appearance. In no place had any adhesion formed between two portions of this deposit. April 29th. Expressed herself as feeling more comfortable. Had some appetite. Pulse not more than 110. Jaundice somewhat decreased per- haps. Bowels more quiet. Tongue dryish and coated. Abdomen not sensitive, rather retracted. No cough. Heart sounds healthy. No delirium or brain symptoms. Voice extremely feeble, but is a little more animated. The liver was of normal size and consistence, but deeply stained with the same yellowish tinge as wore the other organs. April 30th. Stitches removed by Dr. Agnew. The anterior half of fistula found to have healed, this being the twelfth day. The vagina was coated with yellowish layers of lymph, mixed ap- parently with urinary salts. Condition very much the same. Gall-bladder pale and almost empty. Spleen slightly enlarged and rather soft. Pancreas healthy. Kidneys apparently healthy. There was an increase of these appearances over the bladder and rectum, and upon opening bladder, it was found merely much discolored by chronic congestion. It was somewhat thickened, but no evidence of any recent inflammation. May Ist. Much the same. Pulse small, but not so frequent. Skin not harsh. Tongue dry- ish. Jaundice marked. Considerable hebitude, but perfectly rational, and expresses herself af feeling more comfortable and stronger. Her ap- pearance, however, belies her, as she was evi- dently emaciating rapidly. Her voice Avas al- most extinct. She seemed to be more easy when lying on her side, and yet Avas almost unable to turn over. Made no complaint of pain. Had no diarrhoea or vomiting. Took nourishment quite Avell, and passed the day mjich as usual, but about 10, P. M., after having spoken to the night nurse five minutes previously, she was found dead, lying quietly in the same position—on right side. The uterus was of fair size, firm, and on sec- tion, presented a normal appearance. The mu- cous membrane of its cavity was dark and some- what thickened. No evidence of inflammation of uterine veins. Eallopian tubes healthy appa- rently ; calibres free. The fistula Avas found, as stated, reduced in size. Edges presenting a pale granulating sur- face encrusted with phosphates. The neck of uterus, avc have seen, Avas turned into the blad- der, and the highest stitches almost passed through tissue of the os, but no evidence existed of any uterine inflammation, or of the peritonitis having started from this point. Post Mortem, fifteen hours after death. Quite marked rigor mortis. Body emaciated. Spine not examined. Stomach and intestines presented nothing to account for gastro-intestinal symptoms, excepting some softening and thinning of the mucous mem- brane. Brain presented no abnormal condition, save that it, like all other parts of the body, was Urine could not, of course, be obtained. 41 The fluid In abdomen contained granular cor- puscles, with single or double nuclei, some with none apparent, large nucleated cells, a little has- matin. After addition of acetic acid, a few cor- puscles showed trefoil nuclei. Most of the cor- puscles, however, had but one or two. Some coagulation of mucus. The whole being evidently cacoplastic lymphy fluid. The blood, bistre tinted, pale and thin, clotting imperfectly, though quite rapidly, forming large dark clot, full of white corpuscles. No attempt at formation of rouleaux. Red corpusles crena- ted. Quite numerous flakes of hasmatin. loose, with dyspnoea and a sensation of choking; also some tympany; pulse 100. Beef essence, and an enema of tinctures opii gtt. L. in a little starch water. Bth. Eruption made its appearance over the abdomen, resembling that of typhoid fever; belly tympanitic; tongue dry and brown; dyspnoea less; pulse becoming more frequent; twelve of the stitches removed by Dr. Agnew, with the assistance of Dr. Hunt, the union appeared complete, save a small point at the upper ex- tremity of the wound. The removal was dictated by the feeling, thht, possibly, they might have kindled up inflammation, which had extended to the serous lining of the pelvis and abdomen. Ten drops of oil of turpentine, in mucilage, di- rected every two hours; beef essence; milk punch. There was no enlargement of inguinal, pelvic, dr lumbar glands. (Reported by Dr. Andrews, Resident Physician.) Case 17. M. S., set. 38 years, a native of Ire- land, was admitted into the Pennsylvania Hospi- tal, February 13th, 1866, suffering with vesico- vaginal fistula. She was a woman of good habits, but living in a miserable house, in the vicinity of one of our suburban towns. The accident hap- pened with her fifth child; was delivered with instruments, after being in labor two days. Pre- sentation, head. In her former labors she had experienced no trouble. The fistula, on examina- tion, proved to be longitudinal, and quite two inches and a half in length. The tissues ap- peared healthy. After a few days of preparation, consisting in regulating the diet and opening the bowels, the operation for her cure was performed by Dr. Agnew, in presence of Drs. Hunt, Mor- ton, and the Resident physicians of the hospital. The patient being under the influence of ether, the edges were extensively pared, and fourteen silver stitehes inserted, which were secured by the shot- clamp ; the approximation being effected longitu- dinally. She was now placed in bed, a catheter placed in the bladder, and one grain of opium ordered morning and evening. For four days everything went on well; all the urine passing by the catheter, appetite good, pulse normal, and abdomen soft. On the sth she was taken with a severe chill, followed by headache, vomiting, and mental aberration. As she had suffered from chills before entering the hospital, it was hoped this might be nothing more than a return of the intermittent attack, and accordingly quinine was prescribed in antiperiodic doses, 6th. Vomiting continued; bowels loose; deli- rium increased; eyes inflamed; tongue dry and crisped. Lime water and milk administered; also camphor water, with liq. morph, sulphatis. 7th. Some abatement of vomiting; stomach retains a little liquid nourishment; bowels very 9th. Patient exceedingly exhausted; pulse'very frequent; muttering delirium; diarrhoea; enema of laudanum; continue stimulants and nourish- ment. 10th. Died. Post-mortem, six hours after death. Adhesions between the margins of the fistula had given way, and were coated with a dirty lymph; no inflam- mation of bladder or uterus. The viscera of the abdomen were much congested, though not in- flamed. Peyer’s patches healthy; no signs of ul- ceration; no peritonitis; no metastatic abscesses. The lungs somewhat congested, (hypostatic); the pulmonary pleura covered with soft lymph. During life, a blowing sound emitted with the first sound of the heart was noticed, but no lesion of the organ appeared on examination. The blood was remarkably fluid. In all probability, had this patient been operated on outside of the hospital, the termination would have been other- wise. A number of cases of pyaemia having occurred in the wards, the atmospheric conditions were beyond all doubt unsafe. The same may be asserted of Case 16. Case 18. Rose , an Irish-woman, aged about 33 years, was admitted into the Pennsyl- vania Hospital in June, 1866, for vesico-vaginal fistula. On examination, a stricture of the vagina was found about the middle of the canal, the opening not exceeding a quarter of an inch in extent. The tissue around was dense, almost cartilaginous in consistence, and the vagina greatly diminished above. It was, of course impossible to see just where the communication with the bladder existed, but of the fact no doubt existed, as the urine all passed throuoh the vagina. The accident occured in a first labor which had been tedious, lasting two days. Thinks no instruments were used. Did not understand 42 anything was wrong. It was of eight years’ standing, and had once been operated on by a sur- geon without success. Her health was tolerably good, though she was exceedingly nervous. I con- cluded to vivify the edges of the vaginal stricture, and unite them with the metallic threads, thus converting the narrow upper part of the vagina and the bladder into a common cavity. This course was resolved upon, as the thickening and extensive rigidity of the vaginal walls would have made the process of dilatation very slow and unsatisfactory. This was accordingly done, and four sutures inserted, secured in the usual way. The bladder was kept drained with the self- retaining catheter, and everything passed satis- factorily until the fourth day, when she com- plained of great abdominal distension, with severe paroxysms of pain. All of this was due to accu- mulation of flatus, and nothing seemed to control it. Her appetite failed, and she was harassed with nausea. On the ninth day the stitches were taken out, but no union had occurred. She left the hospital with the understanding she should return, with a view of giving her some prelimi- nary general treatment before another operation should be undertaken. ERRATUM. Page 10, 2d column, first line after (Fig. 8), read as follows • to freshen the parts. The lining membrane of the bladder he does not disturb, unless it pro- trudes through the opening in excess. When the fistula was very small he hooked the tenaculum through both sides, and raising it up, cut out a circular portion with the bistoury. When the vesical mucous membrane concealed the margin of the fistula, interfering with its proper manage- ment, a soft sponge should be pressed through the opening into the bladder, and allowed to re- main until the stitches are ready for adjusting. To remove the blood from the parts during the operation, little mops (Fig. 9) should be on hand. These are readily made by securing small bits of sponge, to whalebone, or rods of wood.