Supplement to “The Medical World,” Philadelphia. THE URINE IN DISEASE. 17 Arranged by LOUIS LEWIS, M.D, M.R.C.S., England. Healthy Urine has an Average Specific Gravity of 1020*, and an Acid Reaction! About 45 oz. are daily excreted.J Is of a transparent amber tint.§ , —— ' . = ABNORMAL INGREDIENTS. SPECIFIC GRAVITY. REACTION (WITH LITMUS). QUANTITY. CHARACTERS. TESTS (QUALITATIVE.) REMARKS. • THERAPEUTICAL NOTES. i ALBUMEN. 1015 (and lower). Alkaline (as a rule). Diminished. Smoky, brownish, or blood-red hue. Often odorless. • Heat and Nitric Acid. If albumen be excessive, Heat alone coagulates it. If in small quan- tity, Nitric Acid is required. Excess of Nitric Acid alone coagu- lates it. Bichloride of Mercury, in solution, coagulates it. A small piece of Glacial Acetic Acid dropped into Albuminous Urine, will produce a cloudiness. This test is delicate and reliable. Sulphuric Acid causes a deposit of Carbon (black) in warm Albuminous Urine. .. Picric Acid. A saturated solution causes a pre- cipitate in a thin layer, when carefully added to the Urine. Persistent presence indicates structural Disease of the Kidney : in Bright’s Disease, casts are also found.- Temporarily present in urine containing Pus or Blood; as in inflammatory diseases of the urinary mucous membrane ; also in Intermit- tents, Rheumatic Fever, Pneumonia, Scarlatina, Cholera, etc. Chlorate of Potash, Carbolic Acid and Lead, taken internally, give the same reaction as Albumen. Phosphorus, Cantharides and Turpentine pro- duce Blood. In the various forms of Albuminuria, the following drugs are used : Tincture of Perchloride of Iron, Gallic Acid, Ergot of Rye, Senega, Nitro Glycerine, etc.; also Turkish and Vapour Baths. Gallic and Tannic Acids reduce the amount of Albumen. 2 SUGAR. 1030 (and higher). Acid. Increased. Pale and frothy, with Cider-like Odor. Attracts flies. A deep brown color on boiling with an equal quantity of Liquor Po- tassae. (Moore’s Test.) Fermentation, on addition of yeast, after standing, at a raised tem- perature. A Solution of Sulphate of Copper and Liquor Potassae produces a blue tint, which becomes reddish or orange on the application of Heat. (Trommer’s Test.) Deep green tint on boiling with an alkaline solution of Bichromate of Potash. in extreme cases the odor of burnt sugar is evolved when the Urine is heated over a spirit-lamp on a spatula. Always present in Diabetes. Often associated with Cataract. Temporarily present under the adminis- tration of Ether, Chloroform and Nitrite of Amyl. The Urine of patients taking Salicylic Acid gives the same reaction as Sugar. Dietetics are of first importance. Dilute Phosphoric and Gallic Acids, Tincture of Perchloride of Iron, Permanganate of Potash, Jaborandi, etc., have been variously used. Arsenic and its Bromide, Codeia (in gr. y2 doses), Bromide of Potasium, Salicylate of Soda, Cod Liver Oil, Opium (in large doses), and Sulphide of Calcium are useful in Diabetes Meilitus. Liquid Elxtract of Ergot, Valerian, and Opium are employed in Diabetes Insipidus. Carlsbad and Vichy Waters are also useful. 3 BILE. Slightly increased. Alkaline. Normal. Dark greenish color. Bitter taste. Nitric Acid produces a brownish tint. A purple hue, on addition of Sul- phuric Acid, and a little sugar. (Pettenkoffer’s Test.) Hydrochloric Acid causes a green- ish tint. After shaking up the suspected Urine with the white of an egg, and adding a little nitric acid a green- ish coagulum is produced. Present in Hepatic Derangements. In Jaundice, the Urine imparts a yellow stain to the linen. . - Chloride of Ammonium, Phosphate of Soda, (0 1 doses), Sulphate of Potash, and Tar- axacum, are recommended in Jaundice. Dilute Mineral Acids, Hydrargyrum cum j Creta, Bromide of Potassium, Podophyllin, etc., are used in Hepatic Obstructions. 4 EXCESS OF PHOSPHATES. 1020 (and lower). Alkaline, or neutral. Increased. Cloudy, or ' Pale yellow, with Fetid Odor. Earthy Phosphates (Lime, Magnesia) are precipitated by Aqua Am- monias, Alkaline Phosphates (Soda, Am- monia) are not precipitated by Aqua Ammonias. ' Nitric and Hydrochloric Acids dis- solve earthy and alkaline Phos- phates. Heat precipitates earthy Phosphates, but they are instantly dissolved by Nitric Acid. - . Mostly derived from the food. Excess indicates dis- integration of tissues, and occurs in P’ebrile, In flammatory and Dyspeptic conditions, organic Urinary diseases, and in diseases of the Central Nervous system. Benzoate of Ammonia and Dilute Phosphor- ic Acid are advisable in excess of Phos- phates from ordinary causes. In Rickets, Phosphates of Lime and Iron, and Cod Liver Oil are best. 5 EXCESS OF UREA. 1030 (and higher). Acid (usually). Normal. High color, with strong Urinous Odor. By partly evaporating the urine, and adding an equal quantity of strong Nitric Acid, crystals of Nitrate of Urea are produced. ' AC N • A concentrated solution of Oxalic Acid will produce crystals of Oxalate of Urea, after evapora- tion. Excessive in Acute Inflammatory Fevers. Deficient in organic diseases of the Kidney, Diabetes, Anaemia and ITystencal Conditions. Urea and Uric Acid are products of destruction of Tissues. These are the forms in which Nitrogen is eliminated from the system. Alcohol, Cinchona, Caffein, Lead, and Tea reduce the excretion of Urea, and conse- quently lessen destructive metamor- phosis of tissues. Potash Salts and Chlo- rides of Ammonium and Sodium increase the elimination of Urea. 6 EXCESS OF URIC ACID. 1020 (and higher). Very Acid. Diminished, or Normal, Pligh color, and clear. Hydrochloric Acid, added to urine which has been standing a few hours, throws down a reddish sediment. By adding Glacial Acetic Acid to the Urine, m a watch glass, and leaving some filaments of silk therein. Uric Acid crystals will be deposited in 24 or 48 hours. Increased in Gout, Rheumatism, Pneumonia, Cal- careous Diseases, Diseases of the Liver and some Inflammatory Fevers. In Gout and Rheumatism the increase is especially marked in the Blood. Phosphate of Ammonia, Bicarbonate of Pot- ash, and especially Citrate of Potash, and small doses of Mercury are recommend- i ed, and Hunyadi Janos, Freidrichshall, Carlsbad and Vichy as Mineral Waters; In Gout Colchicum, Citrate of Lithia, Tinc- ture of Iodine (in m.x. doses), Iodide of Potassium, etc. Equal parts of Oil ot Ca- juput and Collodion as a paint; also Poppy i and Soda fomentations. j ' * After drinking freely about 1005 (“ Urina Potus”); after food, about 1030 (‘ Urina Chyli"). f After vegetable diet, Alkaline Reaction; after animal food, Acid Reaction. Excretion diminished when skin acts freely; increased by Digitalis, Scoparius, Squill, Potash Salts, Cantharides, Turpentine, Calomel in small doses frequently repeated, Paraldehyde, etc. §Color heightened by perspiration, and vice versa ; Carbolic Acid darkens it ; Santonin renders it orange ; Beet-root reddens it. A Red Sediment indicates Uric Acid, if crystalline ; otherwise Urate of Ammonia. A White Sediment indicates Phosphates, if soluble in heat ; otherwise, Urate of Ammonia. A Pink Sediment indicates Urate of Soda and osphate of Ammonia. Oxalic Acid is present both in health and disease, and is easily detected by the microscope. Its excess is best treated with Nitric or other mineral acids. Copyright, 1884, by C. F. Taylor. ■ 1 • / {All rights reserved.)