27383. Adulteration and misbranding of Tincture Cinchona Comp. and Powdered 
Extract JTnx Vomica. IT. S. v. Burrougrh Bros. Manufacturing: Co. Plea 
of guilty. Fine, $50 and costs. (F. & D. no. 38045. Sample nos. 70131-B, 
70140-B.)
These products were sold under names recognized in the United States 
Pharmacopoeia and differed from the standard established by that authority.
On April 16, 1937, the United States attorney for the District of Maryland, 
acting upon a report by the Secretary of Agriculture, filed in the district court 
an information against the Burroughs Bros. Manufacturing Co., a corporation 
at Baltimore, Md., alleging shipment by said company in violation of the Food
and Drugs Act on or about April 30, 1936, from the State of Maryland into the 
District of Columbia of quantities of Tincture Cinchona Comp. and Powdered 
Extract Nux Vomica that were adulterated and misbranded. The articles were 
labeled in part: "Tincture Cinchona Comp. U. S. P. X (Tincture Cinchonas 
Composita) Standard: Each 100 cc. contains not less than 0.4 Gm. and not 
more than 0.5 Gm. of Alkaloids"; "Powdered Extract Nux Vomica U. S. P. X 
Strychnos Nux Vomica Contains 15.2 to 16.8% of Alkaloids * * * Burrough 
Bros. Mfg. Co.    *    *    *   Baltimore, Md."
The articles were alleged to be adulterated in that they were sold under and 
by names recognized in the United States Pharmacopoeia and differed from the 
standard of strength, quality, and purity as determined by the tests laid down 
therein in the following respects: The Tincture Cinchona Comp. contained in 
each 100 cubic centimeters less than 0.4 gram of alkaloids of cinchona, whereas 
the pharmacopoeia provided that tincture of cinchona compound should contain 
in each 100 cubic centimeters not less than 0.4 gram of the alkaloids of cin- 
chona ; and the Powdered Extract Nux Vomica yielded not more than 10.97 per- 
cent of the alkaloids of nux vomica, whereas the pharmacopoeia provided that 
extract of nux vomica should yield not less than 15.2 percent of the alkaloids 
of nux vomica; and the standard of strength, quality, and purity of the articles 
was not declared on the containers thereof. The articles were alleged to be 
adulterated further in that their strength and purity fell below the professed 
standard and quality under which they were sold in that they were represented 
to conform to the standards laid down in the United States Pharmacopoeia, 
tenth revision, whereas they did not conform to the standards laid down in 
said pharmacopoeia, tenth revision; and the Tincture Cinchona Comp. was 
represented to contain in each 100 cubic centimeters not less than 0.4 gram 
of the alkaloids of cinchona, whereas each 100 cubic centimeters of the article 
contained not more than 0.352 gram of the alkaloids of cinchona; and the 
Powdered Extract Nux Vomica was represented to contain not less than 15.2 
percent of the alkaloids of nux vomica, whereas it contained not more than 
10.97 percent of the alkaloids of nux vomica.
The articles were alleged to be misbranded in that the statements, "Tincture 
Cinchona Comp. U. S. P. X * * * Each 100 cc. contains not less than 0.4 
Gm. * * * of Alkaloids", and "Powdered Extract Nux Vomica U. S. P. X 
* * * Contains 15.2 to 16.8% of alkaloids", borne on the bottle labels, were 
false and misleading.
On May 20, 1937, a plea of guilty was entered on behalf of the defendant and 
the court imposed a fine of $50 and costs.
M. L. WILSON, Acting Secretary of Agriculture.