719. Adulteration of Estromone.    U.  S. v. Endo Products, Inc.    Plea of guilty.
Fine, $250.     (F. D.  C.  No.  2967.     Sample Nos.  20916-E,  24259-E,  28450-E,
34073-E, 46129-E to 46131-E, incl., 46133-E, 46134-E, 86212-E.)
On February 20, 1942, the United States attorney for the Eastern District
of New York filed an information against Endo Products, Inc., Richmond Hill,
N. Y., alleging shipment within the period from on or about December 28, 1939,
to on or about November 20, 1940, from the State of New Tork into the
States of North Carolina, Pennsylvania, Maryland, and New Jersey of quan-
tities of Estromone which was adulterated.
The article was alleged to be adulterated in that its strength differed from
or its quality fell below that which it purported or was represented to possess
since (1) six of the shipments consisted of tablets which were represented to
possess a biological, activity equivalent to that of 2,000 International Units of
estrogenic hormone; whereas the tablets in five shipments were found to
possess a biological activity equivalent to that of not more than 600 International
Units of estrogenic hormone and those in the sixth shipment possessed a bio-
logical activity equivalent to that of not more than 900 International Units
per tablet. (2) One shipment consisted of tablets which were represented
to possess a biological activity equivalent to that of 4,000 International Units of
estrogenic hormone per tablet; whereas they possessed a biological activity
equivalent to that of not more than 1,800 International. Units of estrogenic
hormone. (3) The remaining shipments were represented to consist of estro-
genic substances in oil possessing in each cubic centimeter a biological activity
equivalent to that of 5,000, 10,000, and 2,000 International Units, respectively,
of estrogenic substance; whereas they possessed a biological activity equiva-
lent to the activity of not more than 1,990, 1,740, and 1,325 International Units,
-respectively, of estrogenic substance.
On April 29, 1942, a plea of guilty was entered on behalf of defendant and
the court imposed a fine of $250.